H. Ariga

发表

DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex.

T. Niki, K. Takahashi-Niki, T. Taira, 2003, Molecular cancer research : MCR.

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

M. Yutsudo, T. Taira, H. Ariga, 2000, Nucleic acids research.

Knockdown of legumain inhibits cleavage of annexin A2 in the mouse kidney.

H. Ariga, H. Ogita, R. Hachisu, 2013, Biochemical and biophysical research communications.

Ku antigen binds to Alu family DNA.

T. Taira, H. Ariga, T. Mimori, 1998, Journal of biochemistry.

A novel DNA replication origin identified in the human heat shock protein 70 gene promoter

T. Taira, H. Ariga, S. Iguchi-Ariga, 1994, Molecular and cellular biology.

A Novel Signaling Pathway Mediated by the Nuclear Targeting of C-Terminal Fragments of Mammalian Patched 1

H. Ariga, H. Kawahara, Hiroki Kagawa, 2011, PloS one.

The Slp Homology Domain of Synaptotagmin-like Proteins 1–4 and Slac2 Functions as a Novel Rab27A Binding Domain*

K. Mikoshiba, H. Ariga, M. Fukuda, 2002, The Journal of Biological Chemistry.

Functional domains involved in the interaction between Orc1 and transcriptional repressor AlF-C that bind to an origin/promoter of the rat aldolase B gene.

H. Ariga, Y. Saitoh, K. Tsutsumi, 2002, Nucleic acids research.

Protease activity of legumain is inhibited by an increase of cystatin E/M in the DJ-1-knockout mouse spleen, cerebrum and heart

H. Ariga, Y. Nakano, Yoshio Yamamoto, 2017, Biochemistry and biophysics reports.

MM-1, a Novel c-Myc-associating Protein That Represses Transcriptional Activity of c-Myc*

T. Taira, S. Iguchi-Ariga, H. Ariga, 1998, The Journal of Biological Chemistry.

AMY-1, a c-Myc-binding Protein, Is Localized in the Mitochondria of Sperm by Association with S-AKAP84, an Anchor Protein of cAMP-dependent Protein Kinase*

T. Taira, S. Iguchi-Ariga, H. Ariga, 2001, The Journal of Biological Chemistry.

Pim‐1 translocates sorting nexin 6/TRAF4‐associated factor 2 from cytoplasm to nucleus

S. Iguchi-Ariga, H. Ariga, K. Tamai, 2001, FEBS letters.

PAP-1, a novel target protein of phosphorylation by pim-1 kinase.

H. Ariga, K. Tamai, M. Ikeda, 2000, European journal of biochemistry.

Membrane cofactor protein (CD46) protects cells predominantly from alternative complement pathway-mediated C3-fragment deposition and cytolysis.

H. Ariga, J. Atkinson, T. Seya, 1993, Journal of immunology.

CHFR Protein Regulates Mitotic Checkpoint by Targeting PARP-1 Protein for Ubiquitination and Degradation*

Tesshi Yamada, M. Toyota, Hiromu Suzuki, 2012, The Journal of Biological Chemistry.

Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice

K. Takata, Y. Kitamura, T. Taniguchi, 2009, Neurochemistry International.

Induction of truncated form of tenascin-X (XB-S) through dissociation of HDAC1 from SP-1/HDAC1 complex in response to hypoxic conditions.

H. Ariga, Ken-ichi Matsumoto, T. Endo, 2008, Experimental cell research.

A novel G1-specific enhancer identified in the human heat shock protein 70 gene.

T. Taira, H. Ariga, S. Iguchi-Ariga, 1997, Nucleic acids research.

ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1

A. Brice, H. Ariga, E. Duplan, 2013, Journal of Cell Science.

PAPA-1 Is a nuclear binding partner of IGFBP-2 and modulates its growth-promoting actions.

H. Ariga, P. Cohen, J. Pintar, 2009, Molecular endocrinology.

Triglyceride accumulation and altered composition of triglyceride‐associated fatty acids in the skin of tenascin‐X‐deficient mice

H. Ariga, K. Kabayama, Ken-ichi Matsumoto, 2004, Genes to cells : devoted to molecular & cellular mechanisms.

DJ-1 associates with synaptic membranes

N. Hattori, T. Hatano, H. Ariga, 2011, Neurobiology of Disease.

High levels of DJ-1 protein and isoelectric point 6.3 isoform in sera of breast cancer patients

T. Ishikawa, H. Ariga, O. Matsubara, 2015, Cancer science.

Distinct localizations and repression activities of MM‐1 isoforms toward c‐Myc

T. Taira, S. Iguchi-Ariga, H. Ariga, 2006, Journal of cellular biochemistry.

MSSP, a protein binding to an origin of replication in the c‐myc gene, interacts with a catalytic subunit of DNA polymerase α and stimulates its polymerase activity

T. Niki, H. Ariga, I. Galli, 2000, FEBS letters.

Modulation of complement regulatory function and measles virus receptor function by the serine-threonine-rich domains of membrane cofactor protein (CD46).

H. Ariga, T. Seya, K. Iwata, 1994, The Biochemical journal.

Distinct glycosylation in interstitial and serum tenascin-X.

H. Ariga, Ken-ichi Matsumoto, T. Kinoshita, 2007, Biological & pharmaceutical bulletin.

Repression of the c‐fms gene in fibroblast cells by c‐Myc‐MM‐1‐TIF1β complex

T. Taira, H. Ariga, Sanae M.M. Iguchi-Ariga, 2004, FEBS letters.

ORC1 interacts with c‐Myc to inhibit E‐box‐dependent transcription by abrogating c‐Myc–SNF5/INI1 interaction

T. Taira, S. Iguchi-Ariga, H. Ariga, 2000, Genes to cells : devoted to molecular & cellular mechanisms.

Transcriptional regulation of the N-myc gene: identification of positive regulatory element and its double- and single-stranded DNA binding proteins.

H. Ariga, T. Nakagawa, S. Iguchi‐Ariga, 1993, Biochimica et biophysica acta.

DJ-1 cooperates with PYCR1 in cell protection against oxidative stress.

S. Shuto, T. Niki, H. Ariga, 2013, Biochemical and biophysical research communications.

Possible function of the c‐myc product: promotion of cellular DNA replication.

H. Ariga, Sanae M. M. Iguchi-Ariga, S. Iguchi‐Ariga, 1987, The EMBO journal.

c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication.

H. Ariga, M. Yamaguchi, S. Iguchi‐Ariga, 1987, Nucleic acids research.

An initiation site of DNA replication with transcriptional enhancer activity present upstream of the c‐myc gene.

H. Ariga, T. Okazaki, Y. Sato, 1988, The EMBO journal.

Protection against oxidative stress-induced neurodegeneration by a modulator for DJ-1, the wild-type of familial Parkinson's disease-linked PARK7.

K. Takata, Y. Kitamura, D. Yanagisawa, 2009, Journal of pharmacological sciences.

A major cellular substrate for protein kinases, annexin II, is a DNA‐binding protein

H. Ariga, M. Svetlova, N. Tomilin, 1994, FEBS letters.

A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus*S⃞

J. Daniel, H. Ariga, E. Ferber, 2008, Journal of Biological Chemistry.

Trypsinogen hL expressed in the human lung is a new member of the trypsinogen family.

H. Ariga, H. Kido, Y. Okumura, 2003, Biological & pharmaceutical bulletin.

Initiation of simian virus 40 DNA replication in vitro

S. Sugano, H. Ariga, Hiroyoshi ARIGAt, 1983, Journal of virology.

Epidermal growth factor-dependent activation of the ERK pathway by DJ-1 through its direct binding to c-Raf*

K. Takahashi-Niki, H. Ariga, Izumi Kato-Ose, 2015 .

Epidermal Growth Factor-dependent Activation of the Extracellular Signal-regulated Kinase Pathway by DJ-1 Protein through Its Direct Binding to c-Raf Protein*

K. Takahashi-Niki, S. Iguchi-Ariga, H. Ariga, 2015, The Journal of Biological Chemistry.

Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress.

H. Ariga, T. Suda, S. Matsuoka, 2014, Blood.

Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism.

T. Niki, T. Taira, H. Ariga, 2003, Acta crystallographica. Section D, Biological crystallography.

A split luciferase-based reporter for detection of a cellular macromolecular complex.

H. Ariga, K. Tomita, H. Maita, 2014, Analytical biochemistry.

Comparative study of hydrogen peroxide- and 4-hydroxy-2-nonenal-induced cell death in HT22 cells

T. Taira, H. Ariga, S. Shimba, 2008, Neurochemistry International.

Serum DJ-1 level is positively associated with improvements in some aspects of metabolic syndrome in Japanese women through lifestyle intervention.

H. Ariga, M. Saito, M. Matsushita, 2014, Nutrition research.

DJ-1 restores p53 transcription activity inhibited by Topors/p53BP3.

T. Niki, T. Taira, S. Iguchi-Ariga, 2005, International journal of oncology.

Extracellular matrix tenascin‐X in combination with vascular endothelial growth factor B enhances endothelial cell proliferation

K. Matsumoto, H. Ariga, Ken-ichi Matsumoto, 2000, Genes to cells : devoted to molecular & cellular mechanisms.

Inhibition of c-myc gene expression in murine lymphoblastoma cells by geldanamycin and herbimycin, antibiotics of benzoquinoid ansamycin group.

H. Ariga, H. Yamaki, S. Iguchi‐Ariga, 1989, The Journal of antibiotics.

Negative transcriptional regulatory element that functions in embryonal carcinoma cells

H. Ariga, K. Ariizumi, H. Takahashi, 1989, Molecular and cellular biology.

New class of polyomavirus mutant that can persist as free copies in F9 embryonal carcinoma cells

H. Ariga, K. Ariizumi, 1986, Molecular and cellular biology.

Identification and characterization of an oocyte factor required for development of porcine nuclear transfer embryos

H. Ariga, N. Binh, Satoshi Tsukamoto, 2011, Proceedings of the National Academy of Sciences.

Characterization of mouse serum tenascin-X.

H. Ariga, Ken-ichi Matsumoto, T. Kinoshita, 2006, DNA and cell biology.

Dihydrotestosterone inhibits tumor necrosis factor alpha induced interleukin-1alpha mRNA expression in rheumatoid fibroblast-like synovial cells.

K. Miyazawa, H. Ariga, Yuka Itoh, 2007, Biological & pharmaceutical bulletin.

Human mucus protease inhibitor in airway fluids is a potential defensive compound against infection with influenza A and Sendai viruses.

H. Ariga, H. Kido, T. Towatari, 1997, Journal of biochemistry.

Neuroprotective Function of DJ-1 in Parkinson's Disease

T. Niki, K. Takahashi-Niki, S. Iguchi-Ariga, 2013, Oxidative medicine and cellular longevity.

Induction of matrix metalloproteinase-2 by tenascin-X deficiency is mediated through the c-Jun N-terminal kinase and protein tyrosine kinase phosphorylation pathway.

H. Ariga, Ken-ichi Matsumoto, Y. Orba, 2004, Experimental cell research.

Structural analysis of mouse tenascin-X: evolutionary aspects of reduplication of FNIII repeats in the tenascin gene family.

T. Ikemura, K. Matsumoto, H. Ariga, 1998, Gene.

Molecular cloning of the mouse AMY-1 gene and identification of the synergistic activation of the AMY-1 promoter by GATA-1 and Sp1.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2003, Genomics.

AMY-1 is a trigger for the erythrocyte differentiation of K562 cells.

T. Taira, H. Ariga, M. Furusawa, 2000, International journal of oncology.

Molecular cloning of MSSP-2, a c-myc gene single-strand binding protein: characterization of binding specificity and DNA replication activity.

H. Ariga, Y. Nishita, S. Iguchi‐Ariga, 1994, Nucleic acids research.

The upstream region of the mouse N-myc gene: identification of an enhancer element that functions preferentially in neuroblastoma IMR32 cells.

H. Ariga, Y. Imamura, Sanae M. M. Iguchi-Ariga, 1992, Biochimica et biophysica acta.

c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of alpha-smooth muscle actin gene in chicken visceral smooth muscle cells.

H. Ariga, K. Sobue, K. Kimura, 1998, Nucleic acids research.

Prefoldin Subunits Are Protected from Ubiquitin-Proteasome System-mediated Degradation by Forming Complex with Other Constituent Subunits*

S. Iguchi-Ariga, H. Ariga, Sanae M. M. Iguchi-Ariga, 2011, The Journal of Biological Chemistry.

Characterization of an element positively regulating the transcription of MSSP gene-2 which encodes C-MYC binding proteins.

H. Ariga, M. Fujimoto, S. Iguchi‐Ariga, 1998, Gene.

BOX DNA: a novel regulatory element related to embryonal carcinoma cell differentiation

R. Tsujita, H. Ariga, Y. Negishi, 1993, Molecular and cellular biology.

Effect of silencer on polyomavirus DNA replication

H. Ariga, K. Ariizumi, H. Takahashi, 1989, Molecular and cellular biology.

A Splicing Reporter Tuned to Non‐AG Acceptor Sites Reveals that Luteolin Enhances the Recognition of Non‐canonical Acceptor Sites

H. Ariga, H. Maita, M. Chiba, 2016, Chemical biology & drug design.

Rabring7 Degrades c-Myc through Complex Formation with MM-1

S. Iguchi-Ariga, H. Ariga, Sanae M. M. Iguchi-Ariga, 2012, PloS one.

MM-1 facilitates degradation of c-Myc by recruiting proteasome and a novel ubiquitin E3 ligase.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2007, International journal of oncology.

Transcription regulatory complex including YB-1 controls expression of mouse matrix metalloproteinase-2 gene in NIH3T3 cells.

H. Ariga, Ken-ichi Matsumoto, S. Abiko, 2005, Biological & pharmaceutical bulletin.

CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.

S. Iguchi-Ariga, H. Ariga, Sanae M. M. Iguchi-Ariga, 2005, Experimental cell research.

Rapid and simple purification of lysozyme from the egg shell membrane.

H. Ariga, Tsutomu Inoue, T. Yamane, 2015, Journal of nutritional science and vitaminology.

Viral DNA synthesis in vitro with the inclusions isolated from adenovirus 12-infected cells.

H. Ariga, H. Shimojo, K. Yamaguchi, 1976, Japanese journal of microbiology.

Mitochondria-independent induction of Fas-mediated apoptosis by MSSP.

S. Iguchi-Ariga, H. Ariga, Ken-ichi Matsumoto, 2005, Oncology Report.

Positive regulation of Fas gene expression by MSSP and abrogation of Fas-mediated apoptosis induction in MSSP-deficient mice.

S. Iguchi-Ariga, H. Ariga, Ken-ichi Matsumoto, 2005, Experimental cell research.

Replication of cloned DNA containing the Alu family sequence during cell extract-promoting simian virus 40 DNA synthesis.

H. Ariga, 1984, Molecular and cellular biology.

Distribution of extracellular matrix tenascin-X in sciatic nerves

H. Ariga, Ken-ichi Matsumoto, Y. Orba, 2002, Acta Neuropathologica.

Transcription and replication silencer element is present within conserved region of human Alu repeats interacting with nuclear protein

H. Ariga, N. Tomilin, Sanae M.M. Iguchi-Ariga, 1990, FEBS letters.

Prefoldin Plays a Role as a Clearance Factor in Preventing Proteasome Inhibitor-induced Protein Aggregation*

K. Takahashi-Niki, S. Iguchi-Ariga, H. Ariga, 2013, The Journal of Biological Chemistry.

A cleavage product of the adenovirus DNA binding protein is active in DNA replication in vitro.

A. Levine, H. Ariga, M. Horwitz, 1980, Virology.

Truncated form of tenascin-X, XB-S, interacts with mitotic motor kinesin Eg5

H. Ariga, Ken-ichi Matsumoto, T. Endo, 2008, Molecular and Cellular Biochemistry.

Stimulation of SV40 DNA replication by the human c‐myc enhancer

S. Iguchi-Ariga, H. Ariga, T. Nakagawa, 1992, FEBS letters.

Inhibition of simian virus 40 replication by kanamycin derivative.

H. Ariga, H. Yamaki, N. Tanaka, 1986, The Journal of antibiotics.

Incorporation of uracil into the growing strand of adenovirus 12 DNA.

H. Ariga, H. Shimojo, 1979, Biochemical and biophysical research communications.

Initiation and termination sites of adenovirus 12 DNA replication. II. Analysis of pulse-labeled oligonucleotides derived from 5' termini in the DNA strand.

H. Ariga, H. Shimojo, 1978, Virology.

Initiation and termination sites of adenovirus 12 DNA replication.

H. Ariga, H. Shimojo, 1977, Virology.

Comparison of the compositions of phospholipid-associated fatty acids in wild-type and extracellular matrix tenascin-X-deficient mice.

H. Ariga, Ken-ichi Matsumoto, J. Inokuchi, 2004, Biological & pharmaceutical bulletin.

Modulation of collagen fibrillogenesis by tenascin-X and type VI collagen.

H. Ariga, Ken-ichi Matsumoto, H. Sawa, 2004, Experimental cell research.

Deficiency of spermatogenesis and reduced expression of spermatogenesis-related genes in prefoldin 5-mutant mice

K. Takahashi-Niki, S. Iguchi-Ariga, H. Ariga, 2015, Biochemistry and biophysics reports.

Transcription factor Sp1 activates the expression of the mouse tenascin-X gene.

K. Matsumoto, H. Ariga, T. Minamitani, 2000, Biochemical and biophysical research communications.

Specific cleavage of the terminal protein from the adenovirus 5 DNA under the condition of single‐strand scission by nuclease S1

H. Ariga, K. Miura, H. Shimojo, 1979, FEBS letters.

Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells.

Tomoya Kinumi, Hiroyoshi Ariga, E. Niki, 2004, Biochemical and biophysical research communications.

The Actin-Binding Domain of Slac2-a/Melanophilin Is Required for Melanosome Distribution in Melanocytes

Mitsunori Fukuda, Hiroyoshi Ariga, H. Ariga, 2003, Molecular and Cellular Biology.

Expression and cellular localization of contraception-associated protein.

H. Ariga, S. Shivaji, V. Sundareswaran, 2000, Journal of andrology.

Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress

Hiroyoshi Ariga, T. Niki, T. Taira, 2005, Free radical research.

DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice.

T. Niki, T. Taira, S. Iguchi-Ariga, 2002, Biological & pharmaceutical bulletin.

DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras.

T. Taira, H. Ariga, K. Tamai, 1997, Biochemical and biophysical research communications.

Immunocytochemical localization of DJ‐1 in human male reproductive tissue

H. Ariga, Yoko Sato, T. Iwamoto, 2003, Molecular reproduction and development.

Inhibition of SV40 DNA replication in vitro by 1-N-acyl-3"-N-(trifluoroacetyl) kanamycin.

H. Ariga, H. Yamaki, N. Tanaka, 1986, Biochemical and biophysical research communications.

Identification of the replicative intermediates in SV40 DNA replication in vitro.

H. Ariga, 1984, Nucleic acids research.

Hepatitis C virus ARFP/F protein interacts with cellular MM-1 protein and enhances the gene trans-activation activity of c-Myc.

S. Iguchi-Ariga, H. Ariga, Ta-Wei Lin, 2008, Journal of biomedical science.

Deficiency of tenascin-X causes a decrease in the level of expression of type VI collagen.

H. Ariga, Ken-ichi Matsumoto, T. Minamitani, 2004, Experimental cell research.

Cross-family interaction between the bHLHZip USF and bZip Fra1 proteins results in down-regulation of AP1 activity

Hiroyoshi Ariga, Philippe Pognonec, H. Kato, 1997, Oncogene.

TOK-1, a Novel p21Cip1-binding Protein That Cooperatively Enhances p21-dependent Inhibitory Activity toward CDK2 Kinase*

S. Iguchi-Ariga, H. Ariga, H. Ugai, 2000, The Journal of Biological Chemistry.

Autonomous replicating sequences from mouse cells which can replicate in mouse cells in vivo and in vitro

H. Ariga, S. Iguchi‐Ariga, T. Itani, 1987, Molecular and cellular biology.

A Novel Transrepression Pathway of c-Myc

T. Taira, S. Iguchi-Ariga, H. Ariga, 2001, The Journal of Biological Chemistry.

MM-1, a c-Myc-binding Protein, Is a Candidate for a Tumor Suppressor in Leukemia/Lymphoma and Tongue Cancer*

T. Taira, S. Iguchi-Ariga, H. Ariga, 2001, The Journal of Biological Chemistry.

Reciprocal Regulation via Protein-Protein Interaction between c-Myc and p21 cip1/waf1/sdi1 in DNA Replication and Transcription*

H. Yoshikawa, S. Iguchi-Ariga, H. Ariga, 2000, The Journal of Biological Chemistry.

AMY‐1, a novel C‐MYC binding protein that stimulates transcription activity of C‐MYC

Takako Onishi, Katsuyuki Tamai, Hiroyoshi Ariga, 1998, Genes to cells : devoted to molecular & cellular mechanisms.

Stimulation of SV40 DNA replication and transcription by Alu family sequence.

H. Ariga, I. Galli, Y. Saëgusa, 1993, Biochimica et biophysica acta.

DJ-1 Positively Regulates the Androgen Receptor by Impairing the Binding of PIASxα to the Receptor*

Hiroyoshi Ariga, Kazuko Takahashi, T. Niki, 2001, The Journal of Biological Chemistry.

Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2009, International journal of oncology.

Cloned mouse DNA fragments can replicate in a simian virus 40 T antigen-dependent system in vivo and in vitro

Z. Tsuchihashi, H. Ariga, M. Yamada, 1985, Molecular and cellular biology.

The Role of Vpr in the Regulation of HIV-1 Gene Expression

H. Ariga, K. Khalili, S. Amini, 2006, Cell cycle.

Transcriptional Activation of Low-Density Lipoprotein Receptor Gene by DJ-1 and Effect of DJ-1 on Cholesterol Homeostasis

T. Niki, K. Takahashi-Niki, S. Iguchi-Ariga, 2012, PloS one.

Human DJ-1-specific Transcriptional Activation of Tyrosine Hydroxylase Gene*

T. Niki, K. Takahashi-Niki, T. Taira, 2010, The Journal of Biological Chemistry.

Oxidative Status of DJ-1-dependent Activation of Dopamine Synthesis through Interaction of Tyrosine Hydroxylase and 4-Dihydroxy-l-phenylalanine (l-DOPA) Decarboxylase with DJ-1*

T. Niki, K. Takahashi-Niki, T. Taira, 2009, The Journal of Biological Chemistry.

DJ-1 interacts with HIPK1 and affects H2O2-induced cell death

T. Niki, T. Taira, S. Iguchi-Ariga, 2006, Free radical research.

Structure and characterization of AAT-1 isoforms.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2005, Biological & pharmaceutical bulletin.

PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor.

S. Iguchi-Ariga, H. Ariga, C. Inglehearn, 2004, Experimental cell research.

A novel nucleolar protein, PAPA-1, induces growth arrest as a result of cell cycle arrest at the G1 phase.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2004, Gene.

Co-localization with DJ-1 is essential for the androgen receptor to exert its transcription activity that has been impaired by androgen antagonists.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2004, Biological & pharmaceutical bulletin.

AMY-1 Interacts with S-AKAP84 and AKAP95 in the Cytoplasm and the Nucleus, Respectively, and Inhibits cAMP-dependent Protein Kinase Activity by Preventing Binding of Its Catalytic Subunit to A-kinase-anchoring Protein (AKAP) Complex*

Hiroyoshi Ariga, T. Taira, S. Iguchi-Ariga, 2002, The Journal of Biological Chemistry.

AAT-1, a Novel Testis-specific AMY-1-binding Protein, Forms a Quaternary Complex with AMY-1, A-kinase Anchor Protein 84, and a Regulatory Subunit of cAMP-dependent Protein Kinase and Is Phosphorylated by Its Kinase*

T. Taira, S. Iguchi-Ariga, H. Ariga, 2002, The Journal of Biological Chemistry.

AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2002, Biochimica et biophysica acta.

Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter.

T. Taira, H. Ariga, S M Iguchi-Ariga, 2001, Gene.

Identification of the initiation region of DNA replication in the murine immunoglobulin heavy chain gene and possible function of the octamer motif as a putative DNA replication origin in mammalian cells.

S. Iguchi-Ariga, H. Ariga, S M Iguchi-Ariga, 1993, Biochimica et biophysica acta.

A eukaryotic nuclear protein of 130 kDa binds to a bacterial cAMP responsive element.

H. Ariga, F. Kihara, 1991, Biochimica et biophysica acta.

Transrepression of the N-myc expression by c-myc protein.

H. Ariga, S. H. Kim, Y. Kubota, 1989, Biochemical and biophysical research communications.

The adenovirus type 12 early-region 1B 58,000-Mr gene product is required for viral DNA synthesis and for initiation of cell transformation

H. Ariga, K. Shiroki, Y. Fukui, 1986, Journal of virology.

DJ-1-binding compound B enhances Nrf2 activity through the PI3-kinase-Akt pathway by DJ-1-dependent inactivation of PTEN

T. Niki, K. Takahashi-Niki, S. Iguchi-Ariga, 2019, Brain Research.

Free radicals impair the anti-oxidative stress activity of DJ-1 through the formation of SDS-resistant dimer

T. Niki, S. Iguchi-Ariga, H. Ariga, 2017, Free radical research.

Transcriptional Regulation of DJ-1.

T. Niki, K. Takahashi-Niki, S. Iguchi-Ariga, 2017, Advances in experimental medicine and biology.

DJ-1 activates SIRT1 through its direct binding to SIRT1.

T. Niki, K. Takahashi-Niki, S. Iguchi-Ariga, 2016, Biochemical and biophysical research communications.

Common mechanisms of onset of cancer and neurodegenerative diseases.

H. Ariga, 2015, Biological & pharmaceutical bulletin.

Identification of the recognition sequence and target proteins for DJ‐1 protease

T. Niki, K. Takahashi-Niki, H. Ariga, 2013, FEBS letters.

Oxidized DJ-1 Inhibits p53 by Sequestering p53 from Promoters in a DNA-Binding Affinity-Dependent Manner

K. Takahashi-Niki, S. Iguchi-Ariga, H. Ariga, 2012, Molecular and Cellular Biology.

Stimulation of vesicular monoamine transporter 2 activity by DJ-1 in SH-SY5Y cells.

T. Niki, K. Takahashi-Niki, H. Ariga, 2012, Biochemical and biophysical research communications.

Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats

Y. Kitamura, K. Takahashi-Niki, H. Ariga, 2011, Molecular Neurodegeneration.

DJ-1-Mediated protective effect of protocatechuic aldehyde against oxidative stress in SH-SY5Y cells.

S. Iguchi-Ariga, H. Ariga, T. Yamane, 2011, Journal of pharmacological sciences.

DJ‐1, an oncogene and causative gene for familial Parkinson's disease, is essential for SV40 transformation in mouse fibroblasts through up‐regulation of c‐Myc

H. Ariga, Sanae M.M. Iguchi-Ariga, H. Kitaura, 2010, FEBS letters.

Correlation between DJ-1 levels in the cerebrospinal fluid and the progression of disabilities in multiple sclerosis patients

H. Ariga, H. Sasaki, M. Hirotani, 2008, Multiple sclerosis.

Protection against nonylphenol-induced cell death by DJ-1 in cultured Japanese medaka (Oryzias latipes) cells.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2006, Toxicology.

Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1.

Takeshi Iwatsubo, Hiroyoshi Ariga, T. Iwatsubo, 2006, Biochemical and biophysical research communications.

Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities

T. Niki, K. Takahashi-Niki, T. Taira, 2006, Cell Death and Differentiation.

Expression profiles of genes in DJ-1-knockdown and L166P DJ-1 mutant cells

K. Takahashi-Niki, T. Taira, S. Iguchi-Ariga, 2005, Neuroscience Letters.

Induction of reactive oxygen species by bisphenol A and abrogation of bisphenol A-induced cell injury by DJ-1.

T. Taira, S. Iguchi-Ariga, H. Ariga, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients.

T. Niki, K. Takahashi-Niki, T. Taira, 2004, Biochemical and biophysical research communications.

DJ‐1 has a role in antioxidative stress to prevent cell death

T. Niki, T. Taira, H. Ariga, 2004, EMBO reports.

The Crystal Structure of DJ-1, a Protein Related to Male Fertility and Parkinson's Disease*

T. Niki, T. Taira, H. Ariga, 2003, Journal of Biological Chemistry.

Complementation of the temperature-sensitive defect in H5ts125 adenovirus DNA replication in vitro.

J. Hurwitz, H. Ariga, L. Kaplan, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Multiple rounds of adenovirus DNA synthesis in vitro.

H. Ariga, M. Horwitz, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Novel Role of Phosphatidylinositol 3-Kinase in CD28-mediated Costimulation*

M. Kubo, H. Ariga, C. June, 2001, The Journal of Biological Chemistry.

EWS/ETS fusions activate telomerase in Ewing's tumors.

T. Taira, H. Ariga, S. Kyo, 2003, Cancer research.

Molecular cloning of the complementary DNA for the mouse pyruvate kinase M-2 gene whose expression is dependent upon cell differentiation.

H. Ariga, A. Manabe, F. Kihara-Negishi, 1995, Biochimica et biophysica acta.

Secretion of DJ-1 into the serum of patients with Parkinson's disease

H. Ariga, H. Sasaki, I. Yabe, 2008, Neuroscience Letters.

Association of PAP-1 and Prp3p, the products of causative genes of dominant retinitis pigmentosa, in the tri-snRNP complex.

S. Iguchi-Ariga, H. Ariga, H. Kitaura, 2005, Experimental cell research.

Improvement of blood glucose levels and obesity in mice given aronia juice by inhibition of dipeptidyl peptidase IV and α-glucosidase.

H. Ariga, Y. Nakano, T. Yamane, 2016, The Journal of nutritional biochemistry.

DJ‐1‐binding compounds prevent oxidative stress‐induced cell death and movement defect in Parkinson’s disease model rats

Y. Kitamura, T. Taira, H. Ariga, 2008, Journal of neurochemistry.

Pyrroloquinoline quinone prevents oxidative stress-induced neuronal death probably through changes in oxidative status of DJ-1.

S. Iguchi-Ariga, H. Ariga, K. Nunome, 2008, Biological & pharmaceutical bulletin.

Efficient Targeted Mutagenesis in Medaka Using Custom-Designed Transcription Activator-Like Effector Nucleases

H. Ariga, R. Takahashi, Takashi Yamamoto, 2013, Genetics.

Primary structure, genomic organization and expression of the major secretory protein of murine epididymis, ME1.

K. Matsumoto, H. Ariga, T. Minamitani, 2000, Gene.

Induction of apoptosis in HeLa cells by MSSP, c-myc binding proteins.

T. Taira, H. Ariga, M. Iida, 1997, Biological & pharmaceutical bulletin.

Identification and cDNA cloning of single-stranded DNA binding proteins that interact with the region upstream of the human c-myc gene.

H. Ariga, K. Tamai, I. Galli, 1994, Oncogene.

H. Ariga, Y. Iwadate, M. Kitagawa, 2011 .

c-myc protein complex binds to two sites in human hsp70 promoter region.

T. Taira, H. Ariga, Y. Negishi, 1992, Biochimica et biophysica acta.

AMY‐1 (associate of Myc‐1) localization to the trans‐Golgi network through interacting with BIG2, a guanine‐nucleotide exchange factor for ADP‐ribosylation factors

S. Iguchi-Ariga, H. Ariga, Hye-Won Shin, 2006, Genes to cells : devoted to molecular & cellular mechanisms.

Diversity of Sites for Measles Virus Binding and for Inactivation of Complement C3b and C4b on Membrane Cofactor Protein CD46 (*)

H. Ariga, M. Okabe, Y. Yanagi, 1995, The Journal of Biological Chemistry.

Prefoldin Protects Neuronal Cells from Polyglutamine Toxicity by Preventing Aggregation Formation*

M. Maeda, S. Iguchi-Ariga, H. Ariga, 2013, The Journal of Biological Chemistry.

Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains.

K. Mikoshiba, H. Ariga, M. Fukuda, 2002, Biochemical and biophysical research communications.

Adhesive defect in extracellular matrix tenascin-X-null fibroblasts: a possible mechanism of tumor invasion.

H. Ariga, Ken-ichi Matsumoto, T. Minamitani, 2002, Biological & pharmaceutical bulletin.

Invasion of Melanoma in Double Knockout Mice Lacking Tenascin‐X and Tenascin‐C

A. Yoshiki, M. Kusakabe, H. Ariga, 2002, Japanese journal of cancer research : Gann.

Tumour invasion and metastasis are promoted in mice deficient in tenascin‐X

H. Ariga, N. Nakatsuji, Ken-ichi Matsumoto, 2001, Genes to cells : devoted to molecular & cellular mechanisms.

Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4‐phenylbutyrate, a chemical chaperone

Kazuyuki Takata, Shun Shimohama, Takashi Yanagida, 2007, Journal of neurochemistry.

PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson’s disease rat model

Kazuyuki Takata, Shun Shimohama, Takashi Yanagida, 2006, Neurobiology of Disease.

Oxidative stress induction of DJ-1 protein

K. Takata, Y. Kitamura, D. Yanagisawa, 2017 .

Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury

K. Takata, Y. Kitamura, D. Yanagisawa, 2009, Oxidative medicine and cellular longevity.

Expression of a hybrid complement regulatory protein, membrane cofactor protein decay accelerating factor on Chinese hamster ovary. Comparison of its regulatory effect with those of decay accelerating factor and membrane cofactor protein.

H. Ariga, T. Seya, K. Iwata, 1994, Journal of immunology.

Establishment of specific antibodies that recognize C106-oxidized DJ-1

S. Iguchi-Ariga, H. Ariga, Sanae M. M. Iguchi-Ariga, 2006, Neuroscience Letters.

DJ-1 Protects Pancreatic Beta Cells from Cytokine- and Streptozotocin-Mediated Cell Death

H. Ariga, D. Eberhard, E. Lammert, 2015, PloS one.

Simian virus 40 DNA replication in vitro: purification and characterization of replication factors from mouse cells.

H. Ariga, 1986, Nucleic acids research.

DJ‐1, a causative gene product of a familial form of Parkinson's disease, is secreted through microdomains

H. Ariga, Ken-ichi Matsumoto, Sanae M.M. Iguchi-Ariga, 2008, FEBS letters.

Expression of a cloned gene segment of poliovirus in E. coli: Evidence for autocatalytic production of the viral proteinase

B. Semler, E. Wimmer, H. Ariga, 1984, Cell.

Effect of tenascin-X together with vascular endothelial growth factor A on cell proliferation in cultured embryonic hearts.

K. Matsumoto, H. Ariga, K. Matsumoto, 2001, Biological & pharmaceutical bulletin.

Prefoldin prevents aggregation of alpha-synuclein

H. Ariga, M. Kinjo, Akira Kitamura, 2019 .

Prefoldin prevents aggregation of α-synuclein

S. Iguchi-Ariga, H. Ariga, M. Kinjo, 2014, Brain Research.

CDC6 interacts with c‐Myc to inhibit E‐box‐dependent transcription by abrogating c‐Myc/Max complex

T. Taira, H. Ariga, S M Iguchi-Ariga, 2000, FEBS letters.

DJ-1 binds to mitochondrial complex I and maintains its activity.

K. Takahashi-Niki, T. Taira, S. Iguchi-Ariga, 2009, Biochemical and biophysical research communications.

Phospholipid modulates in vitro replication of autonomous replicating sequence from human cells.

H. Ariga, H. Umekawa, K. Kojima, 1988, Journal of biochemistry.

Effect of aphidicolin on the elongation step of adenovirus DNA replication in vitro.

H. Ariga, 1983, Biochemical and biophysical research communications.

Transcriptional regulation of the legumain gene by p53 in HCT116 cells.

H. Ariga, L. Kashima, H. Ogita, 2013, Biochemical and biophysical research communications.

Cell Cycle-dependent Switch of Up- and Down-regulation of Human hsp70 Gene Expression by Interaction between c-Myc and CBF/NF-Y*

T. Taira, S. Iguchi-Ariga, H. Ariga, 1999, The Journal of Biological Chemistry.

Activation of c‐myc promoter by c‐myc protein in serum starved cells

T. Taira, H. Ariga, I. Galli, 1991, FEBS letters.

DNA replication origin and transcriptional enhancer in c‐myc gene share the c‐myc protein binding sequences.

H. Ariga, H. Ariga, Y. Imamura, 1989, The EMBO journal.

MSSP promotes ras/myc cooperative cell transforming activity by binding to c‐Myc

T. Niki, T. Taira, S. Iguchi-Ariga, 2000, Genes to cells : devoted to molecular & cellular mechanisms.

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition.

H. Ariga, R. Takahashi, H. Mizusawa, 2003, Biochemical and biophysical research communications.

Monomer DJ-1 and Its N-Terminal Sequence Are Necessary for Mitochondrial Localization of DJ-1 Mutants

S. Iguchi-Ariga, H. Ariga, Sanae M. M. Iguchi-Ariga, 2013, PloS one.

Kaempferol derivatives prevent oxidative stress-induced cell death in a DJ-1-dependent manner.

H. Ariga, W. Qu, L. Fan, 2009, Journal of pharmacological sciences.

Tenascin-X induces cell detachment through p38 mitogen-activated protein kinase activation.

H. Ariga, Ken-ichi Matsumoto, H. Maita, 2009, Biological & pharmaceutical bulletin.

Serum tenascin-X strongly binds to vascular endothelial growth factor.

H. Ariga, Ken-ichi Matsumoto, Taichi Ishitsuka, 2009, Biological & pharmaceutical bulletin.

The AT-rich tract of the SV40 ori core: negative synergism and specific recognition by single stranded and duplex DNA binding proteins

Ivo Galli, Sanae M. M. Iguchi-Ariga, Hiroyoshi Ariga, 1992, Nucleic Acids Res..

Therapeutic effects of human mesenchymal and hematopoietic stem cells on rotenone‐treated parkinsonian mice

K. Yoshimoto, K. Takata, Y. Kitamura, 2012, Journal of neuroscience research.

Effectiveness of aronia berries for reduction of mild fibrosis and gene expression analysis in livers from mice fed a high-fat diet with aronia berries

H. Ariga, Y. Nakano, Yoshio Yamamoto, 2016 .

Mammalian genomic sequences can substitute for the SV40 AT stretch in sustaining replication of the SV40 origin of replication

H. Ariga, I. Galli, Sanae M.M. Iguchi-Ariga, 1993, FEBS letters.

Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim‐1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1 1

T. Taira, S. Iguchi-Ariga, H. Ariga, 2000, FEBS letters.

Disruption of MSSP, c‐myc single‐strand binding protein, leads to embryonic lethality in some homozygous mice

S. Iguchi-Ariga, H. Ariga, Ken-ichi Matsumoto, 2001, Genes to cells : devoted to molecular & cellular mechanisms.

Cloning and characterization of the genomic DNA of the human MSSP genes.

H. Ariga, M. Fujimoto, C. Haigermoser, 1996, Nucleic acids research.

Immunostaining of Oxidized DJ-1 in Human and Mouse Brains

E. Niki, K. Takahashi-Niki, H. Ariga, 2014, Journal of neuropathology and experimental neurology.

Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7.

K. Takata, Y. Kitamura, T. Taniguchi, 2011, Journal of pharmacological sciences.

Distribution of DJ-1, Parkinson's disease-related protein PARK7, and its alteration in 6-hydroxydopamine-treated hemiparkinsonian rat brain.

Kazuyuki Takata, Takashi Yanagida, Hiroyoshi Ariga, 2006, Journal of pharmacological sciences.

DJ-1 Protects against Neurodegeneration Caused by Focal Cerebral Ischemia and Reperfusion in Rats

K. Takata, Y. Kitamura, D. Yanagisawa, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Negative regulation of the Wnt signal by MM-1 through inhibiting expression of the wnt4 gene.

S. Iguchi-Ariga, H. Ariga, Toshiya Sato, 2008, Experimental cell research.

Altered expression of DJ-1 in the hippocampal cells following in vivo and in vitro neuronal damage induced by trimethyltin

T. Taira, H. Ariga, K. Ogita, 2008, Neuroscience Letters.

Expression and protease activity of mouse legumain are regulated by the oncogene/transcription co-activator, DJ-1 through p53 and cleavage of annexin A2 is increased in DJ-1-knockout cells.

H. Ariga, Y. Nakano, Yoshio Yamamoto, 2015, Biochemical and biophysical research communications.

Extracellular signal regulated protein kinase and c-jun N-terminal kinase are involved in ml muscarinic receptor-enhanced interleukin-2 production pathway in Jurkat cells.

H. Ariga, T. Uehara, Y. Nomura, 2000, Biological and Pharmaceutical Bulletin.

Therapeutic Activities of DJ-1 and Its Binding Compounds Against Neurodegenerative Diseases.

Y. Kitamura, D. Yanagisawa, H. Ariga, 2017, Advances in experimental medicine and biology.

Oxidative Neurodegeneration Is Prevented by UCP0045037, an Allosteric Modulator for the Reduced Form of DJ-1, a Wild-Type of Familial Parkinson’s Disease-Linked PARK7

K. Takata, Y. Kitamura, D. Yanagisawa, 2009, International journal of molecular sciences.

Protective effect of planarian DJ-1 against 6-hydroxydopamine-induced neurotoxicity

K. Yoshimoto, K. Takata, Y. Kitamura, 2012, Neuroscience Research.

Specific cleavage of DJ-1 under an oxidative condition

S. Iguchi-Ariga, H. Ariga, Sanae M. M. Iguchi-Ariga, 2006, Neuroscience Letters.

Transcriptional Activation of the Cholecystokinin Gene by DJ-1 through Interaction of DJ-1 with RREB1 and the Effect of DJ-1 on the Cholecystokinin Level in Mice

K. Takahashi-Niki, S. Iguchi-Ariga, H. Ariga, 2013, PloS one.

Transcriptional repression activity of N-MYC protein requires phosphorylation by MAP kinase.

H. Ariga, A. Manabe, S. Iguchi‐Ariga, 1996, Biochemical and biophysical research communications.

Identification and characterization of a dipeptidyl peptidase IV inhibitor from aronia juice.

H. Ariga, Y. Nakano, T. Yamane, 2015, Biochemical and biophysical research communications.

RECRUITMENT OF A TRANSCRIPTIONAL COREPRESSOR COMPLEX TO c-Myc BY MM-1, A c-Myc-BINDING PROTEIN*

T. Taira, H. Ariga, Sanae M. M. Iguchi-Ariga, 2001 .

DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease.

Y. Kitamura, K. Takahashi-Niki, H. Ariga, 2015, Journal of pharmacological sciences.

Protective effect of planarian DJ-1 against 6-hydroxydopamine-induced neurotoxicity

K. Yoshimoto, K. Takata, Y. Kitamura, 2012, Neuroscience Research.

DJ-1 degrades transthyretin and an inactive form of DJ-1 is secreted in familial amyloidotic polyneuropathy.

T. Taira, H. Ariga, Y. Ando, 2007, International journal of molecular medicine.

Identification of DJ-1-Associated Regions on Human Genes from SH-SY5Y Cells using Chromatin Immunoprecipitation Sequence Technique

K. Takahashi-Niki, H. Ariga, T. Yamane, 2014 .

Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury

K. Takata, Y. Kitamura, S. Morikawa, 2009, Oxidative medicine and cellular longevity.

Prefoldin Subunits Are Protected from Ubiquitin-Proteasome System-mediated Degradation by Forming Complex with Other Constituent Subunits*

H. Ariga, Sanae M. M. Iguchi-Ariga, M. Miyazawa, 2011, The Journal of Biological Chemistry.

A simple and efficient liposome method for transfection of DNA into mammalian cells grown in suspension.

T. Tadakuma, H. Ariga, N. Yamaguchi, 1987, Gene.

Structures and comparison of genomic and complementary DNAs of mouse MSSP, a c-Myc binding protein.

K. Matsumoto, H. Ariga, M. Fujimoto, 2000, International journal of oncology.

Effects of a DJ-1-Binding Compound on Spatial Learning and Memory Impairment in a Mouse Model of Alzheimer's Disease.

K. Takata, Y. Kitamura, S. Shimohama, 2016, Journal of Alzheimer's disease : JAD.

Rapid and simple purification of lysozyme from the egg shell membrane.

H. Ariga, Tsutomu Inoue, T. Yamane, 2015, Journal of nutritional science and vitaminology.

Dissociation between the expression of IL 2 receptor and IL 2 receptor mRNA in the antigen-specific T cell clone stimulated by the specific antigen with B cell APC.

H. Ariga, H. Nariuchi, T. Kakiuchi, 1987, Journal of immunology.