G. DeTitta

发表

On the application of the minimal principle to solve unknown structures.

H. Hauptman, R. Miller, G. DeTitta, 1993, Science.

Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data

B. Rost, G. Montelione, M. Baran, 2009, Nature Biotechnology.

Microbatch macromolecular crystallization in micropipettes

George T. DeTitta, Joseph R. Luft, J. Luft, 1999 .

A method to produce microseed stock for use in the crystallization of biological macromolecules.

J. Luft, G. DeTitta, G T DeTitta, 1999, Acta crystallographica. Section D, Biological crystallography.

Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.

T. Earnest, J. Luft, F. Buckner, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.

Oleksandr Kalyuzhniy, Ethan A Merritt, Wim G J Hol, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Macromolecular crystallization in a high throughput laboratory—the search phase

Igor Jurisica, Janice I. Glasgow, George T. DeTitta, 2001 .

ABSORB: An absorption correction program for crystals enclosed in capillaries with trapped mother liquor

G. DeTitta, 1985 .

The rate of water equilibration in vapor-diffusion crystallizations: dependence on the distance from the droplet to the reservoir.

J. Luft, G. DeTitta, J. Baird, 1996, Acta crystallographica. Section D, Biological crystallography.

Blocking S-adenosylmethionine synthesis in yeast allows selenomethionine incorporation and multiwavelength anomalous dispersion phasing

George T. DeTitta, Joseph R. Luft, Michael G. Malkowski, 2007, Proceedings of the National Academy of Sciences.

Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.

T. Earnest, P. Myler, J. Luft, 2006, Journal of medicinal chemistry.

Structure solution by minimal-function phase refinement and Fourier filtering. I. Theoretical basis.

R Miller, C M Weeks, H. Hauptman, 1994, Acta crystallographica. Section A, Foundations of crystallography.

Prostaglandins PGA1 and PGB1. Crystallographic studies of the conformational requirements for 15-hydroxyprostaglandin dehydrogenase activity.

J. W. Edmonds, G. DeTitta, D. Langs, 1979, Biochemistry.

Thromboxane molecules do not adopt the prostaglandin hairpin conformation

G. DeTitta, D. Langs, M. Erman, 1979, Nature.

Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major.

David Baker, Oleksandr Kalyuzhniy, Ethan A Merritt, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

A Macromolecular Crystallization Procedure Employing Diffusion Cells of Varying Depths as Reservoirs to Tailor the Time Course of Equilibration in Hanging- and Sitting-Drop Vapor-Diffusion and Microdialysis Experiments

V. Cody, J. Luft, W. Pangborn, 1994 .

Crystal structure of glyceraldehyde‐3‐phosphate dehydrogenase from Plasmodium falciparum at 2.25 Å resolution reveals intriguing extra electron density in the active site

K. Hodgson, P. Myler, J. Luft, 2005, Proteins.

Standard Reference Material (SRM 1990) For Single Crystal Diffractometer Alignment

J. Armstrong, M. Levenson, G. Enright, 2001, Journal of research of the National Institute of Standards and Technology.

Heterologous expression of L. major proteins in S. cerevisiae: a test of solubility, purity, and gene recoding

E. Phizicky, F. Buckner, W. Hol, 2009, Journal of Structural and Functional Genomics.

Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.

J. Luft, F. Buckner, C. Verlinde, 2008, Journal of molecular biology.

Structure of a ribulose 5‐phosphate 3‐epimerase from Plasmodium falciparum

P. Myler, J. Luft, F. Buckner, 2005, Proteins.

Gearing Up for Structural Genomics: The Challenge of Hundreds of Proteins and Hundreds of Thousands of Crystallization Experiments Per Year

Jennifer R. Wolfley, I. Jurisica, J. Luft, 2000 .

The crystal and molecular structure of the triclinic and monoclinic forms of valinomycin, C54H90N6O18.

J. W. Edmonds, D. Rohrer, G. DeTitta, 1975, Journal of the American Chemical Society.

Thermofluor based high throughput stability optimisation of proteins for structural and functional studies

P. Nordlund, G. DeTitta, N. Dekker, 2006 .

Molecular structure of biotin. Results of two independent crystal structure investigations.

J. W. Edmonds, W. Stallings, G. DeTitta, 1976, Journal of the American Chemical Society.

Cholesteryl myristate: structures of the crystalline solid and mesophases

G. DeTitta, B. Craven, 1976 .

Conformation of O-(L-α-Glyceryl-phosphoryl)-ethanolamine in the Crystal Structure of its Monohydrate

G. DeTitta, B. Craven, 1971 .

Total synthesis of (.+-.)-eriolanin

G. DeTitta, P. Grieco, S. Gilman, 1978 .

High-Resolution X-ray Diffraction and ab Initio Quantum Chemical Studies of Glycoluril, a Biotin Analog

G. DeTitta, M. Dupuis, R. Blessing, 1994 .

Carboxybiotin translocation mechanisms suggested by diffraction studies of biotin and its vitamers.

W. Stallings, G. DeTitta, R. Blessing, 1980, Proceedings of the National Academy of Sciences of the United States of America.

6β,17β-Dihydroxy-6α-pentyl-4-nor-3,5-secoandrostan-3-oic acid. A synthetic prostaglandin analog

G. DeTitta, D. Langs, 1979 .

Structure, absolute configuration, and synthesis of stramonin-B, a new cytotoxic pseudoguaianolide

G. DeTitta, S. Fortier, P. Grieco, 1978 .

Thermofluor-based high-throughput stability optimization of proteins for structural studies.

George T Detitta, Pär Nordlund, P. Nordlund, 2006, Analytical biochemistry.

The molecular conformation of clonidine hydrochloride, an α-adrenergic agonist

V. Cody, G. DeTitta, 1979 .

Conformations of prostaglandin F 2alpha and recognition of prostaglandins by their receptors.

G. DeTitta, D. Langs, M. Erman, 1977, Science.

Prostaglandin B1: the L-shaped prostaglandin.

G. DeTitta, 1976, Science.

The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase.

P. Rathod, J. Luft, F. Buckner, 2010, Journal of molecular biology.

Structure-activity relationships: a look at the structures of PG-related molecules.

G. DeTitta, D. Langs, M. Erman, 1980, Advances in prostaglandin and thromboxane research.

Crystal and molecular structure of 1,4-diphenyl-2,3-dioxabicyclo[2,2,1] heptane, C17H16O2

G. DeTitta, D. Langs, R. G. Salomon, 1978 .

Symmetry in prostaglandins: a critical comment.

G. DeTitta, D. Langs, M. Erman, 1977, Prostaglandins.

Molecular conformation of prostaglandin A1 monoclinic cyrstalline polymorph

J. W. Edmonds, G. DeTitta, W. Duax, 1975 .

l-α-Glycerylphosphorylethanolamine monohydrate

G. DeTitta, B. Craven, 1973 .

The crystal structure of MT0146/CbiT suggests that the putative precorrin-8w decarboxylase is a methyltransferase.

John F Hunt, G. DeTitta, J. Hunt, 2002, Structure.

A deliberate approach to screening for initial crystallization conditions of biological macromolecules.

Joseph R Luft, Christina K. Veatch, J. Luft, 2003, Journal of structural biology.

Non-ideality of aqueous solutions of polyethylene glycol: consequences for its use as a macromolecular crystallizing agent in vapor-diffusion experiments.

J. Luft, G. DeTitta, S. V. Arakali, 1995, Acta crystallographica. Section D, Biological crystallography.

Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies

J. Luft, F. Buckner, C. Verlinde, 2008, Molecular microbiology.

Lessons from high-throughput protein crystallization screening: 10 years of practical experience

Joseph R Luft, Edward H Snell, George T Detitta, 2011, Expert opinion on drug discovery.

Improving Objectivity and Scalability in Protein Crystallization: Integrating Image Analysis With Knowledge Discovery

Igor Jurisica, Robert J. Collins, Janice I. Glasgow, 2001, IEEE Intell. Syst..

Intelligent decision support for protein crystal growth

Igor Jurisica, Janice I. Glasgow, Patrick Rogers, 2001, IBM Syst. J..

Knowledge Management in Scientific Domains

Igor Jurisica, Janice I. Glasgow, Suzanne Fortier, 1999 .

Efficient optimization of crystallization conditions by manipulation

Meriem I. Said, Jennifer R. Wolfley, J. Luft, 2022 .

Purification of transmembrane proteins from Saccharomyces cerevisiae for X-ray crystallography.

G. DeTitta, M. Malkowski, M. Dumont, 2010, Protein expression and purification.

Crystal structure determination of the 1:1 complex of deoxycholic acid and acetic acid

G. DeTitta, B. Craven, 1972 .

On the application of parallel genetic algorithms in X-ray crystallography

Russ Miller, George T. DeTitta, C.-S. Chang, 1994, Proceedings of IEEE Scalable High Performance Computing Conference.

Structure solution by minimal-function phase refinement and Fourier filtering. II. Implementation and applications.

R Miller, C M Weeks, H. Hauptman, 1994, Acta crystallographica. Section A, Foundations of crystallography.

Application of the minimal principle to peptide structures.

R Miller, C M Weeks, H. Hauptman, 1993, Acta crystallographica. Section D, Biological crystallography.

Crystallographic Investigations of Biotin and Carboxybiotin Derivatives a

W. Stallings, G. DeTitta, 1985, Annals of the New York Academy of Sciences.

Automatic classification of sub-microlitre protein-crystallization trials in 1536-well plates.

Igor Jurisica, Christian A Cumbaa, Angela Lauricella, 2003, Acta crystallographica. Section D, Biological crystallography.

Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function.

E. Phizicky, J. Luft, F. Buckner, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural genomics of pathogenic protozoa: an overview.

David Baker, Thomas Earnest, Jürgen Bosch, 2008, Methods in molecular biology.

The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix.

J. Luft, F. Buckner, W. Hol, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Image-Feature Extraction for Protein Crystallization: Integrating Image Analysis and Case-Based Reasoning

Igor Jurisica, Robert J. Collins, Janice I. Glasgow, 2001, IAAI.

[7] Kinetic aspects of macromolecular crystallization.

J. Luft, G. DeTitta, 1997, Methods in enzymology.

HANGMAN: a macromolecular hanging-drop vapor-diffusion technique

J. Luft, G. DeTitta, 1992 .

Determination and application of empirically derived detergent phase boundaries to effectively crystallize membrane proteins

Christina K. Veatch, J. Luft, G. DeTitta, 2009, Protein Science.

Efficient optimization of crystallization conditions by manipulation of drop volume ratio and temperature

Meriem I. Said, Christina K. Veatch, Jennifer R. Wolfley, 2007, Protein science : a publication of the Protein Society.

Carboxybiotin translocation mechanisms suggested by diffraction studies of biotin and its vitamers.

W. Stallings, G. DeTitta, R. Blessing, 1980, Proceedings of the National Academy of Sciences of the United States of America.