D. Langs

发表

On the application of the minimal principle to solve unknown structures.

H. Hauptman, R. Miller, G. DeTitta, 1993, Science.

Crystal structure of an RNA·DNA hybrid reveals intermolecular intercalation: Dimer formation by base-pair swapping

R. Dickerson, M. Sawaya, G. Han, 2003, Proceedings of the National Academy of Sciences of the United States of America.

On 'globbicity' of low-resolution protein structures.

D. Langs, R. Blessing, D. Guo, 1999, Acta crystallographica. Section D, Biological crystallography.

The crystal structures of [Met5]enkephalin and a third form of [Leu5]enkephalin: observations of a novel pleated beta-sheet.

T. Blundell, D. Langs, G. D. Smith, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Factors governing helical preference of peptides containing multiple alpha,alpha-dialkyl amino acids.

G R Marshall, G. Marshall, D. Langs, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Progress on the direct-methods solution of macromolecular structures using single-wavelength anomalous-dispersion (SAS) data.

D. Langs, R. Blessing, D. Guo, 1999, Acta crystallographica. Section A, Foundations of crystallography.

The phase problem in neutron crystallography.

H. Hauptman, D. Langs, 2003, Acta crystallographica. Section A, Foundations of crystallography.

CRUNCH: a phase refinement program for high-resolution macromolecular structures

D. Langs, R. Blessing, G.David Smith, 2000 .

Prostaglandins PGA1 and PGB1. Crystallographic studies of the conformational requirements for 15-hydroxyprostaglandin dehydrogenase activity.

J. W. Edmonds, G. DeTitta, D. Langs, 1979, Biochemistry.

Thromboxane molecules do not adopt the prostaglandin hairpin conformation

G. DeTitta, D. Langs, M. Erman, 1979, Nature.

Globbic approximation in low-resolution direct-methods phasing.

D. Langs, R. Blessing, D. Guo, 2000, Acta crystallographica. Section D, Biological crystallography.

Statistical expectation value of the Debye-Waller factor and E(hkl) values for macromolecular crystals.

D. Langs, R. Blessing, D. Guo, 1996, Acta crystallographica. Section D, Biological crystallography.

Conformational features of calcium channel agonist and antagonist analogs of nifedipine.

D. Langs, D. Triggle, 1984, Molecular pharmacology.

Pharmacologic and radioligand binding analysis of the actions of 1,4-dihydropyridine activators related to Bay K 8644 in smooth muscle, cardiac muscle and neuronal preparations

D. Langs, D. Triggle, A. Joslyn, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Monoclinic uncomplexed double-stranded, antiparallel, left-handed f35-6-helix (TIJ5-6) structure of gramicidin A: Alternate patterns of helical association and deformation

D. Langs, G. D. Smith, C. Courseille, 2022 .

Monoclinic uncomplexed double-stranded, antiparallel, left-handed beta 5.6-helix (increases decreases beta 5.6) structure of gramicidin A: alternate patterns of helical association and deformation.

D. Langs, G. Smith, G. Précigoux, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Use of globic scattering factors for protein structures at low resolution.

D. Langs, D. Guo, G. D. Smith, 1995, Acta crystallographica. Section A, Foundations of crystallography.

Translation vector functions based on a deconvolution of the Patterson function provided by transform methods

D. Langs, 1975 .

The crystal and molecular structure of the triclinic and monoclinic forms of valinomycin, C54H90N6O18.

J. W. Edmonds, D. Rohrer, G. DeTitta, 1975, Journal of the American Chemical Society.

Molecular structure and mechanisms of action of cyclic and linear ion transport antibiotics.

V. Pletnev, D. Langs, W. Duax, 1992, Biopolymers.

Structure of the ion channel peptide antibiotic gramicidin A

D. Langs, 1989, Biopolymers.

The crystal structure of calcium copper acetate hexahydrate and its isomorph calcium cadmium acetate hexahydrate

D. Langs, C. Hare, 1967 .

Ca2+ channel ligands: Structure‐function relationships of the 1,4‐dihydropyridines

D. Langs, D. Triggle, R. Janis, 1989, Medicinal research reviews.

Use of negative quartet cosine invariants as a phasing figure of merit: NQEST

Herbert A. Hauptman, David A. Langs, J. W. Edmonds, 1975 .

N,N-Bis(2-hydroxyethyl)glycine

V. Cody, D. Langs, J. Hazel, 1977 .

Molecular level model for the agonist/antagonist selectivity of the 1,4-dihydropyridine calcium channel receptor

David J. Triggle, David A. Langs, Phyllis D. Strong, 1991, J. Comput. Aided Mol. Des..

Receptor model for the molecular basis of tissue selectivity of 1,4-dihydropyridine calcium channel drugs

David J. Triggle, David A. Langs, Phyllis D. Strong, 1990, J. Comput. Aided Mol. Des..

Chemical structure and pharmacological activities of Ca2+ channel antagonists

D. Langs, D. Triggle, 1984 .

Improvement of SAS triple invariant estimates for macromolecular direct-methods phasing.

D. Langs, R. Blessing, D. Guo, 2001, Acta crystallographica. Section A, Foundations of crystallography.

The conducting form of gramicidin A is a right-handed double-stranded double helix.

W. Pangborn, D. Langs, W. Duax, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Three-dimensional structure at 0.86 A of the uncomplexed form of the transmembrane ion channel peptide gramicidin A.

D. Langs, D A Langs, 1988, Science.

The hydrated potassium complex of the ionophore monensin A

W. Pangborn, D. Langs, W. Duax, 1987 .

Heterodimer formation and crystal nucleation of gramicidin D.

W. Pangborn, D. Langs, W. Duax, 1998, Biophysical journal.

Molecular structure of cyclo[‐(D‐Val‐L‐Hyi‐L‐Val‐D‐Hyi)2‐] revealed by X‐ray analysis

V. Pletnev, D. Langs, W. Duax, 1992, Biopolymers.

6β,17β-Dihydroxy-6α-pentyl-4-nor-3,5-secoandrostan-3-oic acid. A synthetic prostaglandin analog

G. DeTitta, D. Langs, 1979 .

Regular left-handed fragment of amylose: crystal and molecular structure of methyl-α-maltotrioside, 4H2O

W. Pangborn, D. Langs, S. Pérez, 1985 .

Conformations of prostaglandin F 2alpha and recognition of prostaglandins by their receptors.

G. DeTitta, D. Langs, M. Erman, 1977, Science.

Structure-activity relationships: a look at the structures of PG-related molecules.

G. DeTitta, D. Langs, M. Erman, 1980, Advances in prostaglandin and thromboxane research.

Crystal and molecular structure of 1,4-diphenyl-2,3-dioxabicyclo[2,2,1] heptane, C17H16O2

G. DeTitta, D. Langs, R. G. Salomon, 1978 .

Symmetry in prostaglandins: a critical comment.

G. DeTitta, D. Langs, M. Erman, 1977, Prostaglandins.

Chapter 24. Ligand Gated and Voltage-Gated Ion Channels

D. Langs, D. Triggle, 1990 .

Gramicidin D conformation, dynamics and membrane ion transport.

W. Pangborn, V. Pletnev, D. Langs, 1999, Biopolymers.

C-glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin.

D. Langs, H. Li, L. Cappellacci, 1994, Journal of medicinal chemistry.

Molecular structures of two crystalline forms of the cyclic heptapeptide antibiotic ternatin, cyclo[-beta-OH-D-Leu-D-Ile-(NMe)Ala-(NMe)Leu-Leu-(NMe)Ala-D-(NMe)Ala-].

V. Pletnev, R. Miller, D. Langs, 2009, International journal of peptide and protein research.

Ab initio structure determination and refinement of a scorpion protein toxin.

S E Ealick, R Miller, J C Fontecilla-Camps, 1997, Acta crystallographica. Section D, Biological crystallography.

Molecular structure of thyroxine analogues. Crystal structure of 3,5,3'-triiodothyroacetic and 3,5,3',5'-tetraoiodothyroacetic acid N-diethanolamine (1:1) complexes.

V. Cody, D. Langs, W. Duax, 1977, Journal of medicinal chemistry.

Unique solutions for the SIR and SAS phase problems and the use of partial structural information in phase refinement

D. Langs, 1986 .

Structure of gramicidin D-RbCl complex at atomic resolution from low-temperature synchrotron data: interactions of double-stranded gramicidin channel contents and cations with channel wall.

W. Pangborn, D. Langs, Z. Wawrzak, 2005, Acta crystallographica. Section D, Biological crystallography.

Direct methods: a paradox with regard to the convergence of random phase trials toward solutions.

H. Hauptman, D. Langs, 2011, Acta crystallographica. Section A, Foundations of crystallography.

Crystal structure of valinomycin-monohydrate cage complexes crystallized from dioxane.

D. Langs, W. Duax, R. Blessing, 2009, International journal of peptide and protein research.

Rational genomics I: Antisense open reading frames and codon bias in short‐chain oxido reductase enzymes and the evolution of the genetic code

Robert Huether, Lukas Habegger, V. Pletnev, 2005, Proteins.

Relaxation of the resolution requirements for direct-methods phasing.

H. Hauptman, D. Langs, 2011, Acta crystallographica. Section A, Foundations of crystallography.

Structure of pressinoic acid: the cyclic moiety of vasopressin.

R. Hughes, D. Langs, G. D. Smith, 1986, Science.

Intensity Statistics and Normalization

D. Langs, R. Blessing, D. Guo, 1998 .

Chemical analysis by X-ray crystallography—structure of dimethyl sulphone

D. Langs, J. Silverton, W. M. Bright, 1970 .

Use of the minimal function for partial structure development in direct methods.

R Miller, H. Hauptman, G. Han, 1995, Acta crystallographica. Section A, Foundations of crystallography.

Crystal structure of cholesteryl butanoate at 123 K.

G. Han, D. Langs, B. Craven, 1994, Journal of lipid research.

Ion channels in crystals of gramicidin D complex with RbCl. Atomic resolution low-temperature synchrotron X-ray data

W. Pangborn, D. Langs, Z. Wawrzak, 2004 .

Map self-validation: a useful discriminator of phase correctness at low resolution.

D. Langs, R. Blessing, D. Guo, 2001, Acta crystallographica. Section D, Biological crystallography.

Bulk-solvent correction in direct-methods phasing.

D. Langs, R. Blessing, D. Guo, 2000, Acta crystallographica. Section D, Biological crystallography.

Reinvestigation of the use of Patterson maps to extrapolate data to higher resolution.

D. Langs, 1998, Acta crystallographica. Section A, Foundations of crystallography.

Molecular conformation and ion transport of cyclic and linear ionophores.

W. Pangborn, V. Pletnev, D. Langs, 1989, Journal of molecular graphics.

Data averaging with normal down-weighting of outliers

D. Langs, R. Blessing, 1987 .

Structures of two inactive nifedipine analog calcium channel antagonists: (I) C17H17N3O4 and (II) C19H20N2O6

D. Langs, D. Triggle, P. Strong, 1987 .