H. Senderowitz

H. Senderowitz, G. P. Leung, Jeng-Haur Chen, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer.

H. Senderowitz, M. B. Major, D. Offen, 2018, ChemPlusChem.

A bicyclic and hsst2 selective somatostatin analogue: design, synthesis, conformational analysis and binding.

H. Senderowitz, R. Rosenfeld, M. Goodman, 2001, Bioorganic & medicinal chemistry.

Designing a multiroute synthesis scheme in combinatorial chemistry.

R. Shamir, H. Senderowitz, Adi Akavia, 2004, Journal of combinatorial chemistry.

A Practical Method for Calculating Relative Free Energies of Binding. Chiral Recognition of Peptidic Ammonium Ions by Synthetic Ionophores

W. C. Still, H. Senderowitz, A. D. McDonald, 1997 .

JPET #214643 1 Vimocin and Vidapin, cyclic KTS peptides, dual antagonists of α1β1/α2β1 integrins with anti- angiogenic activity

H. Senderowitz, Gadi Cohen, P. Lazarovici, 2014 .

Photovoltaphores: pharmacophore models for identifying metal-free dyes for dye-sensitized solar cells

H. Senderowitz, Hadar Binyamin, 2022, npj Computational Materials.

A Chemical Chaperone‐Based Drug Candidate is Effective in a Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

S. Petri, H. Senderowitz, M. Shubely, 2015, ChemMedChem.

Nrf2 Activation by SK-119 Attenuates Oxidative Stress, UVB, and LPS-Induced Damage

H. Senderowitz, A. Gruzman, G. Cohen, 2019, Skin Pharmacology and Physiology.

RELATIVE STABILITIES AND CONFORMATIONAL RING INVERSION POTENTIALS IN HETEROCYCLIC DECALIN SYSTEMS AND STEREOELECTRONIC IMPLICATIONS

H. Senderowitz, B. Fuchs, L. Golender, 1996 .

New supramolecular host systems. 1. A structural and conformational study of the 1,3,5,7-tetraoxadecalin core system

H. Senderowitz, A. Linden, B. Fuchs, 1994 .

Computation of O-C-F and N-C-F systems : ab-initio calculations and a MM2 parameterization study. Theory vs. experiment

H. Senderowitz, P. Aped, B. Fuchs, 1993 .

Structure, conformation and stereoelectronics of 9,10-annelated-1,4,5,8-tetraoxadecalins: A multidisciplinary probe

H. Senderowitz, I. Goldberg, P. Aped, 1991 .

Conformational energy and entropy differences of the t-butoxy group and implications in stereochemistry and stereoelectronics

H. Senderowitz, P. Aped, B. Fuchs, 1989 .

Neuroligin-2-derived peptide-covered polyamidoamine-based (PAMAM) dendrimers enhance pancreatic β-cells' proliferation and functions.

H. Senderowitz, Aviv Meir, Sharon Ruthstein, 2018, MedChemComm.

Peptide-based development of PKA activators

H. Senderowitz, Sharon Ruthstein, M. Arad, 2018 .

Structurally Simple, Readily Available Peptidomimetic 1-Benzyl-5-methyl-4-( n-octylamino)pyrimidin-2(1 H)-one Exhibited Efficient Cardioprotection in a Myocardial Ischemia (MI) Mouse Model.

H. Senderowitz, Michal Afri, M. Weitman, 2018, Journal of medicinal chemistry.

Molecular Dynamics Flexible Fitting Simulations Identify New Models of the Closed State of the Cystic Fibrosis Transmembrane Conductance Regulator Protein.

H. Senderowitz, N. McCarty, R. Ford, 2017, Journal of chemical information and modeling.

Toward Developing Techniques—Agnostic Machine Learning Classification Models for Forensically Relevant Glass Fragments

H. Senderowitz, M. Braun, O. Girshevitz, 2022, J. Chem. Inf. Model..

Vimocin and Vidapin, Cyclic KTS Peptides, Are Dual Antagonists of α1β1/α2β1 Integrins with Antiangiogenic Activity

H. Senderowitz, Gadi Cohen, P. Lazarovici, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Vimocin and Vidapin , Cyclic KTS Peptides , Are Dual Antagonists of a 1 b 1 / a 2 b 1 Integrins with Antiangiogenic Activity s

H. Senderowitz, Gadi Cohen, P. Lazarovici, 2014 .

Vimocin and Vidapin, cyclic KTS peptides, dual antagonists of 1 integrins with antiangiogenic activity

H. Senderowitz, Gadi Cohen, P. Lazarovici, 2014 .

Docking Studies on DNA Intercalators

Hanoch Senderowitz, Yocheved Gilad, H. Senderowitz, 2014, J. Chem. Inf. Model..

Novel inhibitors of leukocyte transendothelial migration.

H. Senderowitz, N. Khazanov, B. Imhof, 2019, Bioorganic chemistry.

Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives.

Hanoch Senderowitz, Erol Cerasi, Neta Uritsky, 2013, Journal of medicinal chemistry.

Inter-laboratory workflow for forensic applications: Classification of car glass fragments.

H. Senderowitz, O. Girshevitz, K. Mizohata, 2022, Forensic science international.

PIXE based, Machine-Learning (PIXEL) supported workflow for glass fragments classification.

H. Senderowitz, O. Girshevitz, Omer Kaspi, 2021, Talanta.

Phloretin, an Apple Phytoalexin, Affects the Virulence and Fitness of Pectobacterium brasiliense by Interfering With Quorum-Sensing

H. Senderowitz, N. Khazanov, M. Weitman, 2021, Frontiers in Plant Science.

Interkingdom Signaling Interference: The Effect of Plant-Derived Small Molecules on Quorum Sensing in Plant-Pathogenic Bacteria.

H. Senderowitz, N. Khazanov, A. Charkowski, 2021, Annual review of phytopathology.

Direct binding of salicylic acid to Pectobacterium N-acyl-homoserine lactone synthase.

H. Senderowitz, N. Khazanov, S. Burdman, 2020, ACS chemical biology.

Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site

H. Senderowitz, N. Khazanov, H. Eldar-Finkelman, 2020, International journal of molecular sciences.

Structure and conformation of heterocycles. 21. Probing the anomeric effect in orthoesters. Structure, conformation, and dynamic behavior of a unique orthooxalate: 2,5,7,10,11,14-hexaoxa[4.4.4]propellane

H. Senderowitz, I. Goldberg, P. Aped, 1992 .

Probing the Anomeric Effect in OCN Systems Theory vs. Experiment: MO-ab initio Calculations and a Structural-Statistical Analysis†‡

Hanoch Senderowitz, Benzion Fuchs, H. Senderowitz, 1990 .

Carbohydrates: United Atom AMBER* Parameterization of Pyranoses and Simulations Yielding Anomeric Free Energies

Hanoch Senderowitz, W. Clark Still, W. C. Still, 1996 .

Nonhydrolyzable ATP analogues as selective inhibitors of human NPP1: a combined computational/experimental study.

H. Senderowitz, J. Sévigny, J. Pelletier, 2013, Journal of medicinal chemistry.

Dual‐drug RGD conjugates provide enhanced cytotoxicity to melanoma and non‐small lung cancer cells

H. Senderowitz, E. Noy, G. Gellerman, 2016, Biopolymers.

Synthesis, biological studies and molecular dynamics of new anticancer RGD-based peptide conjugates for targeted drug delivery.

Y. Gilad, H. Senderowitz, E. Noy, 2016, Bioorganic & medicinal chemistry.

A novel image-based high-throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease.

Hanoch Senderowitz, Or Kakhlon, Leonardo J Solmesky, 2017, The Biochemical journal.

Discovery of potent molecular chimera (CM358) to treat human metastatic melanoma.

Y. Gilad, H. Senderowitz, G. Gellerman, 2017, European journal of medicinal chemistry.

Evaluation of QSAR Equations for Virtual Screening

Hanoch Senderowitz, Jacob O. Spiegel, Jacob Spiegel, 2020, International journal of molecular sciences.

Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator

J. Riordan, B. Stockwell, N. Dokholyan, 2018, The Journal of Biological Chemistry.

The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue

H. Senderowitz, I. Braakman, Jeong-Soo Hong, 2021, The Journal of biological chemistry.

Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold.

H. Senderowitz, N. Khazanov, J. Sévigny, 2019, European journal of medicinal chemistry.

Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(α or γ)-thio-(α,β- or β,γ)-methylenetriphosphate scaffold.

H. Senderowitz, G. Reiser, J. Sévigny, 2014, Journal of medicinal chemistry.

Materials Informatics

Alexander Tropsha, Hanoch Senderowitz, A. Tropsha, 2019, J. Chem. Inf. Model..

The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3

K. S. Rajan, H. Senderowitz, S. Michaeli, 2021, mBio.

The spliced leader RNA silencing (SLS) pathway in Trypanosoma brucei is induced by perturbations of endoplasmic reticulum, Golgi, or mitochondrial proteins factors and functional analysis of SLS inducing kinase, PK3

K. S. Rajan, H. Senderowitz, S. Michaeli, 2021, bioRxiv.

Activation of PPARδ: from computer modelling to biological effects

H. Senderowitz, A. Livne, A. Gruzman, 2015, British journal of pharmacology.

A novel substrate mimetic inhibitor of PKB/Akt inhibits prostate cancer tumor growth in mice by blocking the PKB pathway.

O. Livnah, H. Senderowitz, A. Levitzki, 2007, Biochemistry.

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.

A. Gaggar, H. Senderowitz, J. Blalock, 2019, Developmental cell.

Potentiators exert distinct effects on human, murine, and Xenopus CFTR.

H. Senderowitz, N. Khazanov, Barry R. Imhoff, 2016, American journal of physiology. Lung cellular and molecular physiology.

Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator

Hanoch Senderowitz, Zhengrong Yang, John F. Hunt, 2021, J. Chem. Inf. Model..

The Q359K/T360K mutation causes cystic fibrosis in Georgian Jews.

H. Mussaffi, D. Prais, M. Mei-Zahav, 2018, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Phenotypic and molecular characteristics of CF patients carrying the I1234V mutation.

H. Senderowitz, N. Khazanov, I. Sarouk, 2020, Respiratory medicine.

Quantitative structure–activity relationship analysis of β-amyloid aggregation inhibitors

Hanoch Senderowitz, Shiri Stempler, Michal Levy-Sakin, 2011, J. Comput. Aided Mol. Des..

Optimization Algorithms for Chemoinformatics and Material-informatics

Abraham Yosipof, Hanoch Senderowitz, H. Senderowitz, 2016 .

Hsp104 facilitates the endoplasmic‐reticulum–associated degradation of disease‐associated and aggregation‐prone substrates

E. Fisher, H. Senderowitz, N. Khazanov, 2019, Protein science : a publication of the Protein Society.

Plant phenolic volatiles inhibit quorum sensing in pectobacteria and reduce their virulence by potential binding to ExpI and ExpR proteins

H. Senderowitz, N. Khazanov, S. Burdman, 2016, Scientific Reports.

Vipegitide: a folded peptidomimetic partial antagonist of α2β1 integrin with antiplatelet aggregation activity

H. Senderowitz, P. Lazarovici, T. Momić, 2015, Drug design, development and therapy.

Diagnostic structural criteria for the anomeric effect in carbohydrates and inferences of general significance on their scope and limitations

Hanoch Senderowitz, Benzion Fuchs, H. Senderowitz, 1990 .

SeleX-CS: A New Consensus Scoring Algorithm for Hit Discovery and Lead Optimization

Hanoch Senderowitz, Shay Bar-Haim, Ayelet Aharon, 2009, J. Chem. Inf. Model..

A comparison and chemometric analysis of several molecular mechanics force fields and parameter sets applied to carbohydrates

Kjeld Rasmussen, Hanoch Senderowitz, Alfred D. French, 1998 .

Guaiacol as a drug candidate for treating adult polyglucosan body disease.

P. Escribá, H. Senderowitz, W. Yue, 2018, JCI insight.

A Comparison between Enrichment Optimization Algorithm (EOA)-Based and Docking-Based Virtual Screening

Jacob O. Spiegel, H. Senderowitz, 2021, International journal of molecular sciences.

Data Mining and Machine Learning Tools for Combinatorial Material Science of All‐Oxide Photovoltaic Cells

Abraham Yosipof, Hanoch Senderowitz, Oren E. Nahum, 2015, Molecular informatics.

Specific stabilization of CFTR by phosphatidylserine.

J. Kappes, H. Senderowitz, N. Khazanov, 2017, Biochimica et biophysica acta. Biomembranes.

2-Hexylthio-β,γ-CH2-ATP is an effective and selective NTPDase2 inhibitor.

H. Senderowitz, J. Sévigny, M. Munkonda, 2014, Journal of medicinal chemistry.

Computation of N-C-N systems: Theory vs. experiment

Hanoch Senderowitz, Benzion Fuchs, H. Senderowitz, 1992 .

Mimicking Neuroligin-2 Functions in β-Cells by Functionalized Nanoparticles as a Novel Approach for Antidiabetic Therapy.

H. Senderowitz, L. Israel, J. Lellouche, 2017, ACS applied materials & interfaces.

REMD Simulations Reveal the Dynamic Profile and Mechanism of Action of Deleterious, Rescuing, and Stabilizing Perturbations to NBD1 from CFTR

Hanoch Senderowitz, Michael Zhenin, Efrat Noy, 2015, J. Chem. Inf. Model..

Conformational Changes Relevant to Channel Activity and Folding within the first Nucleotide Binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator*

Hanoch Senderowitz, Julie D. Forman-Kay, Efrat Noy, 2012, The Journal of Biological Chemistry.

Rescoring of docking poses under Occam’s Razor: are there simpler solutions?

Gilles Marcou, Alexandre Varnek, Dragos Horvath, 2018, Journal of Computer-Aided Molecular Design.

Modified MM2 scheme for computation of OCN‐containing systems

Hanoch Senderowitz, Pinchas Aped, Benzion Fuchs, 1993, J. Comput. Chem..

11th German Conference on Chemoinformatics (GCC 2015)

Timothy Clark, Jonathan W. Essex, Peter Kolb, 2016, J. Cheminformatics.

Structure and Conformation of Heterocycles. Part 20. Structure, Conformation and Stereoelectronics of 9,10-Anellated-1,4,5,8- tetraoxadecalins: A Multidisciplinary Probe

H. Senderowitz, I. Goldberg, P. Aped, 1991 .

Exploring the conformational space of cyclic peptides by a stochastic search method.

A. Rayan, A. Goldblum, H. Senderowitz, 2004, Journal of molecular graphics & modelling.

Improving the Potency of N-Aryl-2,5-dimethylpyrroles against Multidrug-Resistant and Intracellular Mycobacteria.

H. Senderowitz, S. Bhakta, F. Pavan, 2019, ACS medicinal chemistry letters.

G protein coupled receptors -in silico drug discovery and design.

H. Senderowitz, M. Strajbl, E. Ben-Zeev, 2010, Current topics in medicinal chemistry.

Materials Informatics

Alexander Tropsha, Hanoch Senderowitz, A. Tropsha, 2018, J. Chem. Inf. Model..

Design of Compact Biomimetic Cellulose Binding Peptides as Carriers for Cellulose Catalytic Degradation.

H. Senderowitz, N. Khazanov, G. Goobes, 2016, The journal of physical chemistry. B.

Inhibition of AcrAB-TolC enhances antimicrobial activity of phytochemicals in Pectobacterium brasiliense

H. Senderowitz, N. Khazanov, Z. Kerem, 2023, Frontiers in Plant Science.

A comparison between 2D and 3D descriptors in QSAR modeling based on bio‐active conformations

Jacob O. Spiegel, H. Senderowitz, N. Khazanov, 2023, Molecular informatics.

A defective flexible loop contributes to the processing and gating defects of the predominant cystic fibrosis‐causing mutation

H. Senderowitz, Jeng-Haur Chen, Samuel J. Bose, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Data Mining and Machine Learning Tools for Combinatorial Material Science of All‐Oxide Photovoltaic Cells

Oren E. Nahum, Assaf Y Anderson, H. Senderowitz, 2015, Molecular informatics.

Optimization of Molecular Representativeness

Abraham Yosipof, Hanoch Senderowitz, H. Senderowitz, 2014, J. Chem. Inf. Model..

Dynamic Classification for Materials‐Informatics: Mining the Solar Cell Space

Roy Gelbard, Abraham Yosipof, Hanoch Senderowitz, 2020, Molecular informatics.

Application of Materials Informatics Tools to the Analysis of Combinatorial Libraries of All Metal-Oxides Photovoltaic Cells

Abraham Yosipof, Hanoch Senderowitz, Omer Kaspi, 2019, ICANN.

Visualization of Solar Cell Library Space by Dimensionality Reduction Methods

Abraham Yosipof, Hanoch Senderowitz, Omer Kaspi, 2018, J. Chem. Inf. Model..

RANdom SAmple Consensus (RANSAC) algorithm for material-informatics: application to photovoltaic solar cells

Abraham Yosipof, Hanoch Senderowitz, Omer Kaspi, 2017, Journal of Cheminformatics.