S. Toler

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3D Molecular Descriptors Important for Clinical Success

David Kombo, Kartik Tallapragada, Rachit Jain, 2013, J. Chem. Inf. Model..

Oxidative Stress Plays an Important Role in the Pathogenesis of Drug-Induced Retinopathy

S. Toler, 2004, Experimental biology and medicine.

Population pharmacokinetics of TC‐5214, a nicotinic channel modulator, in phase I and II clinical studies

S. Toler, Hongmei Xu, N. Al-Huniti, 2014, Journal of clinical pharmacology.

Two-Dimensional Regulation of CAR-T Cell Therapy with Orthogonal Switches

Wei-Chun Chang, S. Toler, J. Bayle, 2018, Molecular therapy oncolytics.

Clinical Pharmacokinetics of the Nicotinic Channel Modulator Dexmecamylamine (TC-5214) in Subjects with Various Degrees of Renal Impairment

S. Toler, H. Eriksson, R. Tummala, 2014, Clinical Drug Investigation.

Phase 2 Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) in Negative and Cognitive Symptoms of Schizophrenia.

G. Dunbar, S. Marder, J. Kane, 2016, Schizophrenia bulletin.

Intraperitoneal and intraportal administration of droloxifene to the Sprague-Dawley rat: assessing the first-pass effect.

S. Toler, D. Nickerson, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

Preclinical pharmacology of CP-424,391, and orally active pyrazolinone-piperidine growth hormone secretagogue

S. Toler, B. Lefker, J. A. Ragan, 2001, Endocrine.

Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs). Discovery of capromorelin.

S. Toler, B. Lefker, J. A. Ragan, 2003, Bioorganic & medicinal chemistry.

Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine [correction of pyrazolidinone-piperidine] growth hormone secretagogue.

S. Toler, D. Thompson, B. Lefker, 2001, Endocrine.

Invited review: fluphenazine augments retinal oxidative stress.

S. Toler, 2005, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

A double-blind placebo-controlled evaluation of the acute effects of sildenafil citrate (Viagra) on visual function in subjects with early-stage age-related macular degeneration.

W. Swanson, G. Fish, A. Laties, 2002, American journal of ophthalmology.

Safety and efficacy of sildenafil citrate for the treatment of female sexual arousal disorder: a double-blind, placebo controlled study.

S. Toler, L. Berman, J. Berman, 2003, The Journal of urology.

Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene.

S. Toler, M. J. Cole, D. Thompson, 1998, Journal of medicinal chemistry.

Selective enhancement of cellular oxidative stress by chloroquine: implications for the treatment of glioblastoma multiforme.

D. Noe, S. Toler, Amarnath Sharma, 2006, Neurosurgical focus.

The plasmodial apicoplast was retained under evolutionary selective pressure to assuage blood stage oxidative stress.

S. Toler, 2005, Medical hypotheses.

Anticholinergic therapy for overactive bladder: a nicotinic modality?

S. Toler, M. Chancellor, P. Lippiello, 2013, Medical hypotheses.

Renal toxicity in dogs associated with the maleate salt, not with the tosylate salt of TC-5619

S. Toler, J. Xie, 2010 .

Clinical Efficacy and Tolerability of the Nicotinic Channel Modulator Dexmecamylamine in Subjects with Overactive Bladder.

S. Toler, M. Chancellor, E. Versi, 2015, The Journal of urology.

Anticholinergic therapy for overactive bladder: a nicotinic modality?

S. Toler, M. Chancellor, P. Lippiello, 2013, Medical hypotheses.

First-pass metabolism and biliary recirculation of droloxifene in the female Sprague-Dawley rat.

S. Toler, D. Tess, D. Nickerson, 1997, Xenobiotica; the fate of foreign compounds in biological systems.