J. Strachan

发表

Synthesis of 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane, and 2-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, a class of potent nicotinic acetylcholine receptor-ligands.

W. S. Caldwell, P. Crooks, C. Miller, 2008, The Journal of organic chemistry.

Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs).

D. Kombo, A. Mazurov, J. Speake, 2014, European journal of medicinal chemistry.

Ground and Excited State Electronic Properties of Halogenated Tetraarylporphyrins. Tuning the Building Blocks for Porphyrin-based Photonic Devices

J. Strachan, Dongho Kim, J. Lindsey, 1999 .

Rational synthesis of beta-substituted chlorin building blocks.

J. Strachan, J. Lindsey, T. Balasubramanian, 2000, The Journal of organic chemistry.

Rational synthesis of meso-substituted chlorin building blocks.

J. Strachan, J. Lindsey, D. O’Shea, 2000, The Journal of organic chemistry.

Rational synthesis of meso-substituted chlorin building blocks.

J. Strachan, J. Lindsey, T. Balasubramanian, 2000, The Journal of organic chemistry.

Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents.

Laura G. Dubois, Philip F. Hughes, J. Strachan, 2009, Journal of medicinal chemistry.

Effects of Orbital Ordering on Electronic Communication in Multiporphyrin Arrays

J. Strachan, J. Lindsey, J. Seth, 1997 .

The preparation of some 1,7b-disubstituted cyclopropa[c]isoquinolines via nitrile ylide cyclisations and their rearrangement to 2-benzazepines and 4-alkenyl-1,4-dihydroisoquinolines

J. Strachan, J. Sharp, S. Parsons, 1998 .

Synthesis and Characterization of Tetrachlorodiarylethyne-Linked Porphyrin Dimers. Effects of Linker Architecture on Intradimer Electronic Communication.

J. Strachan, J. Lindsey, J. Seth, 1998, Inorganic chemistry.

Discovery of 3-(5-chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a novel highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders.

D. Kombo, A. Mazurov, J. Speake, 2012, Journal of medicinal chemistry.

A route to 1,4-prop[2]enoisoquinolines via the cyclisation of triene-conjugated nitrile ylides1

J. Strachan, J. Sharp, Melanie J. Crawshaw, 1999 .

Reactions of triene-conjugated nitrile ylides: a route to 1,4-dihydro-1,4-prop-1′-enoisoquinolines from systems with α,β aromatic and γ,δ; Îµ,ζ olefinic unsaturation

J. Strachan, J. Sharp, S. Parsons, 1996 .

Trans-Substituted porphyrin building blocks bearing iodo and ethynyl groups for applications in bioorganic and materials chemistry

J. Strachan, J. Lindsey, M. Ravikanth, 1998 .

trans‐Substituted Porphyrin Building Blocks Bearing Iodo and Ethynyl Groups for Applications in Bioorganic and Materials Chemistry.

J. Strachan, J. Lindsey, M. Ravikanth, 1998 .

α4β2 nicotinic receptors play a role in the nAChR-mediated decline in l-dopa-induced dyskinesias in parkinsonian rats

J. Strachan, M. Quik, T. Bordia, 2013, Neuropharmacology.

Rational Synthesis of Meso-Substituted Chlorin Building Blocks.

J. Strachan, J. Lindsey, T. Balasubramanian, 2000, The Journal of organic chemistry.

Diazaspirocyclic compounds as selective ligands for the α4β2 nicotinic acetylcholine receptor.

J. J. Farias, B. Bhatti, J. Strachan, 2012, Bioorganic & medicinal chemistry letters.

Pharmacological properties and predicted binding mode of arylmethylene quinuclidine-like derivatives at the α3β4 nicotinic acetylcholine receptor (nAChR).

D. Kombo, Kartik Tallapragada, J. Chewning, 2013, Bioorganic & medicinal chemistry letters.