Shann-Ching Chen

发表

A novel approximate inference approach to automated classification of protein subcellular location patterns in multi-cell images

Robert F. Murphy, Geoffrey J. Gordon, Shann-Ching Chen, 2006, 3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, 2006..

Automated image analysis of protein localization in budding yeast

Robert F. Murphy, Geoffrey J. Gordon, Ting Zhao, 2007, ISMB/ECCB.

The genomic landscape of hypodiploid acute lymphoblastic leukemia

Robert Huether, Jinghui Zhang, Matthew Parker, 2013, Nature Genetics.

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.

Ryan D. Morin, Michael N. Edmonson, M. Loh, 2012, Cancer cell.

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

Z. Szallasi, Clarence C Lee, T. Harkins, 2014, Science.

The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.

C. Mullighan, D. Meyerholz, Shann-Ching Chen, 2012, Immunity.

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Kiran C. Bobba, Kimberly J. Johnson, Michael C. Rusch, 2012, Nature.

Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia.

Mondira Kundu, Shann-Ching Chen, J. Downing, 2013, The Journal of clinical investigation.

Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration

Gaudenz Danuser, Shann-Ching Chen, G. Danuser, 2014, Cell.

oGNM: online computation of structural dynamics using the Gaussian Network Model

Hassan A. Karimi, Ivet Bahar, Xiong Liu, 2006, Nucleic Acids Res..

Genomic Characterization and Experimental Modeling Of BCR-ABL1 -Like Acute Lymphoblastic Leukemia

Michael C. Rusch, M. Loh, J. Downing, 2013 .

Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms.

J. Downing, M. L. Le Beau, Shann-Ching Chen, 2015, Blood.

Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis

J. Downing, E. Passegué, Jing Ma, 2015, eLife.

Development and Validation Of a Highly Sensitive and Specific Gene Expression Classifier To Prospectively Screen and Identify B-Precursor Acute Lymphoblastic Leukemia (ALL) Patients With a Philadelphia Chromosome-Like (“Ph-like” or “BCR-ABL1-Like”) Signature For Therapeutic Targeting and Clinical In

Michael C. Rusch, M. Loh, D. Gerhard, 2013 .

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

Heather L. Mulder, Erin K. Hedlund, Michael C. Rusch, 2014, The New England journal of medicine.

Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts

J. Downing, M. L. Le Beau, Shann-Ching Chen, 2014, Haematologica.

Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia

J. Downing, J. Aster, W. Pear, 2014, Nature.

Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair

H. Pasolli, E. Fuchs, Shann-Ching Chen, 2012, Cell.

An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.

Heather L. Mulder, S. Ranade, R. Wilson, 2012, Cancer cell.

Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential

C. Mullighan, Shann-Ching Chen, M. Churchman, 2014, The Journal of experimental medicine.

LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans

Gavin D. Meredith, G. Daley, S. Ogino, 2015, Genes & development.

LIN 28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans

Gavin D. Meredith, G. Daley, S. Ogino, 2015 .

subtypes of T-cell acute lymphoblastic leukemia tumor suppressor is mutated across the major molecular BCL11B The

J. Downing, L. Chin, F. Alt, 2013 .

The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.

J. Downing, L. Chin, F. Alt, 2011, Blood.

Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia

Hugo Y. K. Lam, G. Nolan, A. Butte, 2018, Genome research.

Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.

Taosheng Chen, Junmin Peng, Jing Ma, 2015, Cancer cell.

Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation.

James Downing, Megan E McNerney, Kevin M Haigis, 2013, Cancer discovery.

Philadelphia-positive acute lymphoblastic leukemia in a case of MPL p.(W515L) variant essential thrombocythemia: case report and literature review

Shann-Ching Chen, Z. Ge, J. Zi, 2021, Platelets.

Defective K-Ras oncoproteins overcome impaired effector activation to initiate leukemia in vivo.

J. Downing, C. Mullighan, Jin Xu, 2013, Blood.

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

Rohini Rau-Murthy, Jinghui Zhang, Kenneth Offit, 2013, Nature Genetics.

Integrated Genomic and Mutational Profiling Of Adolescent and Young Adult ALL Identifies a High Frequency Of BCR-ABL1-Like ALL with Very Poor Outcome

M. Loh, J. Downing, C. Bloomfield, 2013 .

Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness

Jeffrey A. Magee, S. Morrison, J. Magee, 2013, Nature.

A graphical model approach to automated classification of protein subcellular location patterns in multi-cell images

Robert F. Murphy, Shann-Ching Chen, R. Murphy, 2006, BMC Bioinformatics.

Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project

Kiran C. Bobba, Kimberly J. Johnson, R. Wilson, 2011 .

Association of the variations in the HSD3&bgr; gene with primary aldosteronism

Yen-Hung Lin, Shann-Ching Chen, S. Chueh, 2013, Journal of hypertension.

Automatic Hip Detection in Anteroposterior Pelvic Radiographs—A Labelless Practical Framework

Mel S. Lee, Shann-Ching Chen, Chien-Hung Liao, 2021, Journal of personalized medicine.

Graphical Models for Structured Classification, with an Application to Interpreting Images of Protein Subcellular Location Patterns

Robert F. Murphy, Geoffrey J. Gordon, Shann-Ching Chen, 2008, J. Mach. Learn. Res..

Identification of a novel metastasis-suppressor region on human chromosome 12.

M. L. Le Beau, Shann-Ching Chen, K. Watabe, 1998, Cancer research.

Author response: Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis

J. Downing, E. Passegué, Jing Ma, 2015 .

Integrated Genetic and Epigenetic Analysis of Childhood Acute Lymphoblastic Leukemia Reveals a Synergistic Role for Structural and Epigenetic Lesions In Determining Disease Phenotype

J. Downing, Cheng Cheng, A. Melnick, 2010 .

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

Z. Szallasi, Clarence C Lee, T. Harkins, 2014, Science.