H. Baker

发表

Crystal structures and iron release properties of mutants (K206A and K296A) that abolish the dilysine interaction in the N-lobe of human transferrin.

D. Nurizzo, H. Baker, Q. He, 2001, Biochemistry.

Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.

H. Baker, R. MacGillivray, A. Mason, 1998, Biochemistry.

Structure of human lactoferrin at 3.2-A resolution.

H. Baker, E. Baker, B. Anderson, 1987, Proceedings of the National Academy of Sciences of the United States of America.

A structural framework for understanding the multifunctional character of lactoferrin.

H. Baker, E. Baker, 2009, Biochimie.

Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold.

E N Baker, H. Baker, E. Baker, 2001, Structure.

Anion binding by transferrins: importance of second-shell effects revealed by the crystal structure of oxalate-substituted diferric lactoferrin.

H. Baker, E. Baker, B. Anderson, 1996, Biochemistry.

Anion binding by human lactoferrin: results from crystallographic and physicochemical studies.

H. Baker, E. Baker, C. Smith, 1992, Biochemistry.

Do glutathione and related enzymes play a role in drug resistance in small cell lung cancer cell lines?

H. Baker, S. Cole, B. Campling, 1993, British Journal of Cancer.

Secretion of atrial natriuretic peptide and vasopressin by small cell lung cancer

T. Flynn, H. Baker, S. Pang, 1995, Cancer.

Structure, function and flexibility of human lactoferrin.

H. Baker, E. Baker, B. Anderson, 1991, International journal of biological macromolecules.

Three-dimensional structure of lactoferrin in various functional states.

H. Baker, E. Baker, B. Anderson, 1994, Advances in experimental medicine and biology.

Zinc-Binding Ligands in Human Milk

H. Baker, S. Rumball, J. Plowman, 1981 .

A structural perspective on lactoferrin function.

H. Baker, E. Baker, 2012, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Spectroscopic studies on metal complexes of Aspergillus awamori-derived recombinant human lactoferrin

H. Baker, E. Baker, J. Swarts, 2000 .

Preliminary crystallographic studies on bovine lactoferrin.

H. Baker, E. Baker, B. Anderson, 1986, Journal of molecular biology.

Establishment and characterization of a panel of human lung cancer cell lines

H. Baker, W. Bradley, J. Holden, 1992 .

Chemosensitivity testing of small cell lung cancer using the MTT assay.

H. Baker, S. Cole, B. Campling, 1991, British Journal of Cancer.

Metal and anion binding sites in lactoferrin and related proteins

H. Baker, E. Baker, B. Anderson, 1990 .

Three-Dimensional Structure of Lactoferrin

H. Baker, R. MacGillivray, E. Baker, 1998 .

Three-dimensional structure of lactoferrin. Implications for function, including comparisons with transferrin.

H. Baker, R. MacGillivray, E. Baker, 1998, Advances in experimental medicine and biology.

Purification, crystallization and preliminary X-ray analysis of Enterococcus faecium aminoglycoside-2''-phosphotransferase-Ib [APH(2'')-Ib].

H. Baker, E. Baker, P. Young, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Oligomerization and ligand binding in a homotetrameric hemoglobin: Two high‐resolution crystal structures of hemoglobin Bart's (γ4), a marker for α‐thalassemia

H. Baker, E. Baker, A. Mathews, 2001, Protein science : a publication of the Protein Society.

Expression, crystallization and preliminary characterization of methylmalonyl coenzyme A epimerase from Propionibacterium shermanii.

H. Baker, E. Baker, A. McCarthy, 2001, Acta crystallographica. Section D, Biological crystallography.

Crystallization of sheep liver cytosolic aldehyde dehydrogenase in a form suitable for high resolution X-ray structural analysis.

H. Baker, E. Baker, T. Kitson, 1995, Advances in experimental medicine and biology.

Preliminary crystallographic studies on human apo-lactoferrin in its native and deglycosylated forms.

H. Baker, E. Baker, G. Norris, 1989, Journal of molecular biology.

X-ray structural analysis of bovine lactoferrin at 2.5 A resolution.

H. Baker, E. Baker, B. Anderson, 1994, Advances in experimental medicine and biology.

Metal substitution in transferrins: specific binding of cerium(IV) revealed by the crystal structure of cerium-substituted human lactoferrin

H. Baker, E. Baker, Clyde A. Smith, 2000, JBIC Journal of Biological Inorganic Chemistry.

Calcium-mediated thermostability in the subtilisin superfamily: the crystal structure of Bacillus Ak.1 protease at 1.8 A resolution.

H. Baker, E. Baker, C. Smith, 1999, Journal of molecular biology.

Preliminary crystallographic studies of copper(II)- and oxalate-substituted human lactoferrin.

H. Baker, E. Baker, C. Smith, 1991, Journal of molecular biology.

Structure of human lactoferrin: crystallographic structure analysis and refinement at 2.8 A resolution.

D. Rice, H. Baker, E. Baker, 1989, Journal of molecular biology.

Chelation of nickel(II) by citrate. The crystal structure of a nickel–citrate complex, K2[Ni(C6H5O7)(H2O)2]2·4H2O

H. Baker, E. Baker, B. Anderson, 1983 .

Crystal structure of Escherichia coli manganese superoxide dismutase at 2.1-Å resolution

J. W. Whittaker, H. Baker, E. Baker, 1998, JBIC Journal of Biological Inorganic Chemistry.

Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.

H. Baker, E. Baker, F. Coulibaly, 2012, Acta crystallographica. Section D, Biological crystallography.

Metal substitution in transferrins: the crystal structure of human copper-lactoferrin at 2.1-A resolution.

H. Baker, E. Baker, B. Anderson, 1992, Biochemistry.

Lactoferrin Is a Potent Regulator of Bone Cell Activity and Increases Bone Formation in Vivo

Edward N Baker, Jillian Cornish, Dorit Naot, 2022 .

Molecular structure, binding properties and dynamics of lactoferrin.

H. Baker, E. N. Baker, 2005, Cellular and molecular life sciences : CMLS.

Structural basis of the Tanford transition of bovine beta-lactoglobulin.

E N Baker, B. Qin, H. Baker, 1998, Biochemistry.

Elongation of the Poly-γ-glutamate Tail of F420 Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis*

H. Baker, E. Baker, G. Bashiri, 2016, The Journal of Biological Chemistry.

The structure of truncated recombinant human bile salt-stimulated lipase reveals bile salt-independent conformational flexibility at the active-site loop and provides insights into heparin binding.

H. Baker, E. Baker, S. Moore, 2001, Journal of molecular biology.

Crystal structures of the staphylococcal toxin SSL5 in complex with sialyl Lewis X reveal a conserved binding site that shares common features with viral and bacterial sialic acid binding proteins.

H. Baker, E. Baker, J. Fraser, 2007, Journal of molecular biology.

Molecular structure, binding properties and dynamics of lactoferrin.

H. Baker, E. Baker, Edward N. Baker, 2005, Cellular and molecular life sciences : CMLS.

Lactoferrin and Iron: structural and dynamic aspects of binding and release

H. Baker, E. Baker, 2004, Biometals.

Apolactoferrin structure demonstrates ligand-induced conformational change in transferrins

Edward N. Baker, Sylvia V. Rumball, H. Baker, 1990, Nature.

Dealing with iron: Common structural principles in proteins that transport iron and heme

H. Baker, E. Baker, B. Anderson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Lactoferrin and transferrin: functional variations on a common structural framework.

Edward N Baker, H. Baker, E. Baker, 2002, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Structural and Functional Properties of Staphylococcal Superantigen-Like Protein 4

H. Baker, E. Baker, Richard P Sequeira, 2012, Infection and Immunity.

Crystal structure of a truncated mutant of glucose-fructose oxidoreductase shows that an N-terminal arm controls tetramer formation.

G. Sprenger, H. Baker, E. Baker, 2000, Journal of molecular biology.

The crystal structure of staphylococcal superantigen‐like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition

H. Baker, E. Baker, J. Fraser, 2007, Molecular microbiology.

Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease.

J. Musser, H. Baker, E. Baker, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.

D. Nurizzo, H. Baker, A. Mason, 2007, Acta crystallographica. Section D, Biological crystallography.

Crystallographic and Mutational Data Show That the Streptococcal Pyrogenic Exotoxin J Can Use a Common Binding Surface for T-cell Receptor Binding and Dimerization*

V. Arcus, H. Baker, E. Baker, 2004, Journal of Biological Chemistry.

1.8 A crystal structure of the C-terminal domain of rabbit serum haemopexin.

H. R. Faber, C. Groom, H. Baker, 1995, Structure.

Structure of recombinant human lactoferrin expressed in Aspergillus awamori.

H. Baker, E. Baker, G. Jameson, 1999, Acta crystallographica. Section D, Biological crystallography.

Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases.

H. Baker, E. Baker, S. Moore, 1998, Structure.

A structural explanation for the retinal specificity of class 1 ALDH enzymes.

H. Baker, E. Baker, S. Moore, 1999, Advances in experimental medicine and biology.

The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes.

H. Baker, E. Baker, E. Parker, 2005, Journal of molecular biology.

Crystallization and preliminary X-ray crystallographic analysis of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Mycobacterium tuberculosis.

Edward N Baker, Emily J Parker, H. Baker, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two β-propeller domains

Edward N. Baker, William T. Morgan, Massimo Paoli, 1999, Nature Structural Biology.

Crystallographic studies on metal and anion substituted human lactoferrin.

H. Baker, E. Baker, B. Anderson, 1994, Advances in experimental medicine and biology.

Establishment and characterization of a panel of human lung cancer cell lines.

H. Baker, J. Holden, B. Campling, 1992, Cancer.

Search designs for protein crystallization based on orthogonal arrays.

E N Baker, H. Baker, E. Baker, 1994, Acta crystallographica. Section D, Biological crystallography.

Subunit dissociation and reassociation leads to preferential crystallization of haemoglobin Bart's (γ4) from solutions of human embryonic haemoglobin Portland (ζ2γ2) at low pH

H. Baker, E. Baker, A. Mathews, 2001 .

Crystal structure of a human embryonic haemoglobin: the carbonmonoxy form of gower II (alpha2 epsilon2) haemoglobin at 2.9 A resolution.

H. Baker, E. Baker, A. Sutherland-Smith, 1998, Journal of molecular biology.

Search Designs for Protein Crystallization Based on

H. Baker, E. Baker, R. Kingston, 1994 .

Doglutathione andrelated enzymesplay a role indrugresistance insmall cell lung cancercell lines

H. Baker, S. Cole, B. Campling, 1993 .

Crystal structure of a sigma 28-regulated non-flagella virulence protein from campylobacter jejuni

E. Goldsmith, M. Perbandt, C. Betzel, 2008 .

Lactoferrin

H. Baker, E. N. Baker, 2005, Cellular and Molecular Life Sciences.

Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes.

V. Arcus, H. Baker, E. Baker, 2000, Journal of molecular biology.

Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin.

H. Baker, A. Mason, E. Baker, 2003, Biochemistry.

High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon.

Edward N Baker, J. Oakeshott, R. Russell, 2007, Biochemistry.

Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding.

H. Baker, E. Baker, E. Parker, 2012, Biochemistry.

Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis*

H. Baker, E. Baker, G. Jameson, 2010, The Journal of Biological Chemistry.

Altered Domain Closure and Iron Binding in Lactoferrin Mutants

H. Nicholson, H. R. Faber, H. Baker, 1997 .

Enzymatic deglycosylation as a tool for crystallization of mammalian binding proteins.

H. Baker, E. Baker, G. Norris, 1994, Acta crystallographica. Section D, Biological crystallography.

Human melanotransferrin (p97) has only one functional iron‐binding site

H. Baker, E. Baker, M. Kahn, 1992, FEBS letters.

Structural and Functional Flexibility of Lactoferrin

H. R. Faber, H. Baker, E. Baker, 1997 .

Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes.

H. Baker, E. Baker, Qing‐Yu He, 2009, Biochemistry.

Crystal structure of the streptococcal superantigen SPE-C: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules

H. Baker, E. Baker, B. Anderson, 1997, Nature Structural Biology.

A flexible and economical medium-throughput strategy for protein production and crystallization.

V. Arcus, H. Baker, E. Baker, 2005, Acta crystallographica. Section D, Biological crystallography.

Specific binding of cerium by human lactoferrin stimulates the oxidation of Ce3+ to Ce4+

H. Baker, E. Baker, Clyde A. Smith, 1994 .

Single molecule force spectroscopy on G-quadruplex DNA.

H. Baker, Dejian Zhou, K. Sinniah, 2009, Chemistry.

Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo.

I. Reid, H. Baker, E. Baker, 2004, Endocrinology.

Elongation of the Poly-γ-glutamate Tail of F420 Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis*

H. Baker, E. Baker, G. Bashiri, 2016, The Journal of Biological Chemistry.

Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis*

H. Baker, E. Baker, G. Jameson, 2010, The Journal of Biological Chemistry.

Crystallization and preliminary X-ray analysis of native and recombinant human bile-salt dependent lipase: strategies for improvement of diffraction quality.

H. Baker, E. Baker, O. Hernell, 2000, Acta Crystallographica Section D: Biological Crystallography.

Synergism and substitution in the lactoferrins.

H. Baker, E. Baker, C. Smith, 1994, Advances in experimental medicine and biology.

Structure of copper- and oxalate-substituted human lactoferrin at 2.0 A resolution.

H. Baker, E. Baker, B. Anderson, 1994, Acta crystallographica. Section D, Biological crystallography.