E. Baker

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Crystal structures and iron release properties of mutants (K206A and K296A) that abolish the dilysine interaction in the N-lobe of human transferrin.

D. Nurizzo, H. Baker, Q. He, 2001, Biochemistry.

Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.

R. MacGillivray, A. Mason, R. Woodworth, 1998, Biochemistry.

Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.

H. Baker, R. MacGillivray, A. Mason, 1998, Biochemistry.

The TB Structural Genomics Consortium: a decade of progress.

D. Eisenberg, M. James, J. Sacchettini, 2011, Tuberculosis.

Hydrogen bonding in globular proteins.

E. Baker, R. Hubbard, 1984, Progress in biophysics and molecular biology.

Structure of human lactoferrin at 3.2-A resolution.

H. Baker, E. Baker, B. Anderson, 1987, Proceedings of the National Academy of Sciences of the United States of America.

A structural framework for understanding the multifunctional character of lactoferrin.

H. Baker, E. Baker, 2009, Biochimie.

Correction for Manríquez et al., Adaptive shell color plasticity during the early ontogeny of an intertidal keystone snail

S. Grossman, E. Baker, A. Kung, 2009, Proceedings of the National Academy of Sciences.

Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN‐domain (VapC) protein from a toxin‐antitoxin operon

V. Arcus, E. Baker, R. D. Bunker, 2008, Proteins.

Superantigen Architecture: Functional Decoration on a Conserved Scaffold

V. Arcus, E. Baker, 2007 .

The Three-dimensional Structure of a Superantigen-like Protein, SET3, from a Pathogenicity Island of the Staphylococcus aureus Genome*

V. Arcus, E. Baker, T. Proft, 2002, The Journal of Biological Chemistry.

REVIEW ARTICLE: Biopolymers

E. Baker, D. Parry, E. N. Baker, 1984 .

The cloning, expression and crystallisation of a thermostable arginase

E. Baker, M. Bewley, J. Lott, 1996, FEBS letters.

Engineering a Lys-Asn isopeptide bond into an immunoglobulin-like protein domain enhances its stability

E. Baker, P. Young, H. Kwon, 2017, Scientific Reports.

Domain closure in lactoferrin. Two hinges produce a see-saw motion between alternative close-packed interfaces.

M Gerstein, B F Anderson, E N Baker, 1993, Journal of molecular biology.

Structure of naphthoate synthase (MenB) from Mycobacterium tuberculosis in both native and product-bound forms.

Edward N Baker, Vickery L Arcus, V. Arcus, 2005, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold.

E N Baker, H. Baker, E. Baker, 2001, Structure.

Stabilizing Isopeptide Bonds Revealed in Gram-Positive Bacterial Pilus Structure

Edward N. Baker, E. Baker, T. Proft, 2007, Science.

Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.

E. Baker, S. Panjikar, M. Brimble, 2016, Angewandte Chemie.

Total chemical synthesis of an Orf virus protein, ORFV002, an inhibitor of the master gene regulator NF‐κB

E. Baker, S. Kent, M. Brimble, 2014, Biopolymers.

Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug Development.

E. Baker, T. Laue, J. Carpenter, 2017, Journal of pharmaceutical sciences.

Expectation bias and information content

Zbigniew Dauter, Howard Einspahr, Edward N. Baker, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal Structures of E. coli Native MenH and Two Active Site Mutants

Zhihong Guo, E. Baker, J. Johnston, 2013, PloS one.

Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis.

Zhihong Guo, E. Baker, J. Johnston, 2010, Acta crystallographica. Section D, Biological crystallography.

New perspectives on the structure and function of transferrins.

E. Baker, P. Lindley, 1992, Journal of inorganic biochemistry.

Protein-binding Properties of two Antitumour Ru(III) Complexes to Human Apotransferrin and Apolactoferrin

E. Baker, C. Smith, B. Keppler, 1994, Metal-based drugs.

The Laminin-Binding Protein Lbp from Streptococcus pyogenes Is a Zinc Receptor

E. Baker, C. Linke, T. Proft, 2009, Journal of bacteriology.

Anion binding by transferrins: importance of second-shell effects revealed by the crystal structure of oxalate-substituted diferric lactoferrin.

H. Baker, E. Baker, B. Anderson, 1996, Biochemistry.

Anion binding by human lactoferrin: results from crystallographic and physicochemical studies.

H. Baker, E. Baker, C. Smith, 1992, Biochemistry.

Preparation of truncated orf virus entry fusion complex proteins by chemical synthesis

E. Baker, M. Brimble, P. Harris, 2014, Journal of peptide science : an official publication of the European Peptide Society.

Crystal Structure of a Putative Methyltransferase from Mycobacterium tuberculosis: Misannotation of a Genome Clarified by Protein Structural Analysis

V. Arcus, E. Baker, M. Parker, 2003, Journal of bacteriology.

Anthranilate phosphoribosyltransferase: Binding determinants for 5'-phospho-alpha-d-ribosyl-1'-pyrophosphate (PRPP) and the implications for inhibitor design.

E. Baker, E. Parker, J. Lott, 2018, Biochimica et biophysica acta. Proteins and proteomics.

Repurposing the Chemical Scaffold of the Anti‐Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis

S. Gamage, W. Denny, E. Baker, 2014, Chembiochem : a European journal of chemical biology.

The three-dimensional structure of PNGase F, a glycosylasparaginase from Flavobacterium meningosepticum.

T. J. Stillman, E. Baker, B. Anderson, 1994, Structure.

Structure, function and flexibility of human lactoferrin.

H. Baker, E. Baker, B. Anderson, 1991, International journal of biological macromolecules.

The three-dimensional structure of PNGase F, a glycosyl asparaginase from Flavobacterium meningosepticum

T. J. Stillman, E. Baker, B. Anderson, 1994 .

Purification and crystallization of the endoglycosidase PNGase F, a peptide:N-glycosidase from Flavobacterium meningosepticum.

C. H. Moore, E. Baker, G. Norris, 1994, Journal of molecular biology.

Three-dimensional structure of cytochrome c' from two Alcaligenes species and the implications for four-helix bundle structures.

H. R. Faber, E. Baker, B. Anderson, 1996, Acta crystallographica. Section D, Biological crystallography.

Use of a "silver bullet" to resolve crystal lattice dislocation disorder: a cobalamin complex of Δ1-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis.

E. Baker, G. Bashiri, T. Lagautriere, 2015, Journal of structural biology.

The structure and unusual protein chemistry of hypoxic response protein 1, a latency antigen and highly expressed member of the DosR regulon in Mycobacterium tuberculosis.

E. Baker, J. Lott, Chen Gao, 2008, Journal of molecular biology.

Roles of Minor Pilin Subunits Spy0125 and Spy0130 in the Serotype M1 Streptococcus pyogenes Strain SF370

E. Baker, B. Hirst, M. Banfield, 2010, Journal of bacteriology.

Making sense of a missense mutation: characterization of MutT2, a Nudix hydrolase from Mycobacterium tuberculosis, and the G58R mutant encoded in W-Beijing strains of M. tuberculosis.

E. Baker, J. Lott, C. Charlier, 2009, Biochemistry.

Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis

E. Baker, J. Johnston, E. M. Bulloch, 2020, The Journal of Biological Chemistry.

Allosteric Regulation of Vitamin K2 Biosynthesis in a Human Pathogen

E. Baker, J. Johnston, E. M. Bulloch, 2019, bioRxiv.

Group A Streptococcus T Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design

E. Baker, T. Proft, P. Young, 2019, Infection and Immunity.

Three-dimensional structure of lactoferrin in various functional states.

H. Baker, E. Baker, B. Anderson, 1994, Advances in Experimental Medicine and Biology.

Crystallization and preliminary X-ray investigation of rabbit plasma transferrin.

D. Moss, E. Baker, P. Lindley, 1976, Journal of molecular biology.

Aminoglycoside antibiotic resistance by enzymatic deactivation.

E. Baker, Clyde A. Smith, 2002, Current drug targets. Infectious disorders.

Mapping of the ATP-binding domain of human fructosamine 3-kinase-related protein by affinity labelling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.

E. Baker, G. Cooper, M. Middleditch, 2008, The Biochemical journal.

Ligand promiscuity within the internal cavity of Epiphyas postvittana Takeout 1 protein.

E. Baker, R. Newcomb, D. Greenwood, 2013, Journal of structural biology.

Crystal Structure of Epiphyas postvittana Takeout 1 with Bound Ubiquinone Supports a Role as Ligand Carriers for Takeout Proteins in Insects*

E. Baker, R. Newcomb, D. Greenwood, 2009, Journal of Biological Chemistry.

A structural perspective on lactoferrin function.

H. Baker, E. Baker, 2012, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Spectroscopic studies on metal complexes of Aspergillus awamori-derived recombinant human lactoferrin

H. Baker, E. Baker, J. Swarts, 2000 .

Preliminary crystallographic studies on bovine lactoferrin.

H. Baker, E. Baker, B. Anderson, 1986, Journal of molecular biology.

Protein adhesins as vaccine antigens for Group A Streptococcus.

E. Baker, T. Proft, P. Young, 2018, Pathogens and disease.

Structural Conservation, Variability, and Immunogenicity of the T6 Backbone Pilin of Serotype M6 Streptococcus pyogenes

E. Baker, T. Proft, P. Young, 2014, Infection and Immunity.

Expression, purification, crystallization and preliminary crystallographic analysis of SpaA, a major pilin from Corynebacterium diphtheriae.

E. Baker, N. Paterson, H. Kang, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Working towards a group A streptococcal vaccine: report of a collaborative Trans-Tasman workshop.

E. Baker, J. Carapetis, M. Baker, 2014, Vaccine.

Structural Model for Covalent Adhesion of the Streptococcus pyogenes Pilus through a Thioester Bond*

E. Baker, G. Witte, N. Paterson, 2013, The Journal of Biological Chemistry.

Fate of water in subducted hydrous sediments deduced from stability fields of FeOOH and AlOOH up to 20 GPa

T. Yoshino, E. Baker, Kyle Duffey, 2019, Physics of the Earth and Planetary Interiors.

Structure and assembly of Gram-positive bacterial pili: unique covalent polymers.

E. Baker, H. Kang, 2012, Current opinion in structural biology.

Purification, crystallization and preliminary crystallographic analysis of mouse myo-inositol oxygenase.

E. Baker, G. Cooper, T. Caradoc-Davies, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site.

E. Baker, E. M. Bulloch, R. Payne, 2012, Organic & biomolecular chemistry.

High throughput crystallography of TB drug targets.

D. Eisenberg, J. Berger, M. James, 2007, Infectious disorders drug targets.

Structural and Functional Characterization of an RNase HI Domain from the Bifunctional Protein Rv2228c from Mycobacterium tuberculosis (cid:1)

E. Baker, Harriet A. Watkins, 2010 .

Metal and anion binding sites in lactoferrin and related proteins

H. Baker, E. Baker, B. Anderson, 1990 .

Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation

E. Baker, M. Brimble, T. Proft, 2014, PloS one.

Making the most of two crystals: structural analysis of a conserved hypothetical protein using native gel screening and SAD phasing.

E. Baker, J. Lott, M. Banfield, 2003, Acta crystallographica. Section D, Biological crystallography.

Defining the Potassium Binding Region in an Apple Terpene Synthase*

E. Baker, W. Laing, S. Green, 2009, Journal of Biological Chemistry.

The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds

E. Baker, N. Paterson, H. Kang, 2009, Proceedings of the National Academy of Sciences.

Three-Dimensional Structure of Lactoferrin

H. Baker, R. MacGillivray, E. Baker, 1998 .

Three-dimensional structure of lactoferrin. Implications for function, including comparisons with transferrin.

H. Baker, R. MacGillivray, E. Baker, 1998, Advances in experimental medicine and biology.

The structure of 2Zn pig insulin crystals at 1.5 A resolution.

T L Blundell, S M Cutfield, J F Cutfield, 1988, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Crystal structure of kiwellin, a major cell-wall protein from kiwifruit.

E. Baker, R. Atkinson, D. Brummell, 2014, Journal of structural biology.

An arm-swapped dimer of the Streptococcus pyogenes pilin specific assembly factor SipA.

E. Baker, H. Kang, P. Young, 2013, Journal of structural biology.

Recombinant Human Lactoferrin and Its Variants

T. Yip, T. Hutchens, E. Baker, 1997 .

The characterization of both the coordinated and non-coordinated saccharinate ion. The syntheses and crystal structures of aqua(2-formylpyridine thiosemicarbazonato)(saccharinato-N)copper(II) hemihydrate and 2,2′-bipyridyl-(2-formylpyridine thiosemicarbazonato)copper(II) saccharinate dihydrate

E. Baker, J. Waters, J. Ranford, 1990 .

Structure of apo-azurin from Alcaligenes denitrificans at 1.8 A resolution.

E. Baker, B. Anderson, W. Shepard, 1993, Acta crystallographica. Section D, Biological crystallography.

CopperThe relative rigidity of the type 1 copper site in azurin, as seen in high resolution X-ray analyses of various forms of the protein.

E. Baker, B. Anderson, W. Shepard, 1991 .

Expression, purification and crystallization of a membrane-associated, catalytically active type I signal peptidase from Staphylococcus aureus.

E. Baker, P. Young, Y. Ting, 2015, Acta crystallographica. Section F, Structural biology communications.

Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis.

E. Baker, J. Johnston, E. M. Bulloch, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification, crystallization and preliminary crystallographic analysis of human dihydrodipicolinate synthase-like protein (DHDPSL).

E. Baker, R. D. Bunker, K. Loomes, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification, crystallization and preliminary X-ray analysis of Enterococcus faecium aminoglycoside-2''-phosphotransferase-Ib [APH(2'')-Ib].

H. Baker, E. Baker, P. Young, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Purification, crystallization and preliminary X-ray analysis of Escherichia coli UDP-N-acetylmuramoyl:L-alanine ligase (MurC).

E. Baker, B. Leiting, Clyde A. Smith, 2003, Acta crystallographica. Section D, Biological crystallography.

Oligomerization and ligand binding in a homotetrameric hemoglobin: Two high‐resolution crystal structures of hemoglobin Bart's (γ4), a marker for α‐thalassemia

H. Baker, E. Baker, A. Mathews, 2001, Protein science : a publication of the Protein Society.

Expression, crystallization and preliminary characterization of methylmalonyl coenzyme A epimerase from Propionibacterium shermanii.

H. Baker, E. Baker, A. McCarthy, 2001, Acta crystallographica. Section D, Biological crystallography.

Crystallization of sheep liver cytosolic aldehyde dehydrogenase in a form suitable for high resolution X-ray structural analysis.

H. Baker, E. Baker, T. Kitson, 1995, Advances in experimental medicine and biology.

Preliminary crystallographic studies of the amino terminal half of human lactoferrin in its iron-saturated and iron-free forms.

E. Baker, B. Anderson, C. Day, 1992, Journal of molecular biology.

Preliminary crystallographic studies on human apo-lactoferrin in its native and deglycosylated forms.

H. Baker, E. Baker, G. Norris, 1989, Journal of molecular biology.

Purification and preliminary crystallographic studies on azurin and cytochrome c' from Alcaligenes denitrificans and Alcaligenes sp. NCIB 11015.

E. Baker, B. Anderson, G. Norris, 1979, Journal of molecular biology.

Synthetic, spectroscopic and X-ray crystallographic studies on phenylcyanamidocopper(I) complexes

E. Baker, J. Waters, P. Healy, 1991 .

Synthetic, spectroscopic, and X-ray crystallographic studies on phenylcyanamidocopper(II) complexes. The characterization of three different co-ordination modes for phenylcyanamide anions

E. Baker, M. Brader, E. Ainscough, 1990 .

Copper (II) promoted desulphurization of N-phenylthiourea. The synthesis and X-ray structure of [{Cu(bipy)(pc)2}2] (bipy=2,2'-bipyridine, pc=phenylcyanamide)

E. Baker, M. Brader, E. Ainscough, 1989 .

Isolation and characterization of a gene encoding a drought-induced cysteine protease in tomato (Lycopersicon esculentum).

E. Baker, Z. Tabaeizadeh, H. Harrak, 2001, Genome.

Regulation of human 4-hydroxy-2-oxoglutarate aldolase by pyruvate and α-ketoglutarate. Implications for Primary Hyperoxaluria Type-3.

E. Baker, R. D. Bunker, J. Burke, 2019, The Biochemical journal.

X-ray structural analysis of bovine lactoferrin at 2.5 A resolution.

H. Baker, E. Baker, B. Anderson, 1994, Advances in experimental medicine and biology.

Convergent pathways to biosynthesis of the versatile cofactor F420.

E. Baker, G. Bashiri, 2020, Current opinion in structural biology.

Human milk lactoferrin is a serine protease that cleaves Haemophilus surface proteins at arginine‐rich sites

E. Baker, D. Hendrixson, D. Fink, 2003, Molecular microbiology.

Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae.

E. Baker, D. Hendrixson, J. S. St. Geme, 1998, Proceedings of the National Academy of Sciences of the United States of America.

STRUCTURE OF DIFERRIC BOVINE LACTOFERRIN AT 2.8 ANGSTROMS RESOLUTION

C. Groom, E. Baker, S. Moore, 1997 .

Three-dimensional structure of diferric bovine lactoferrin at 2.8 A resolution.

C. Groom, E. Baker, S. Moore, 1997, Journal of molecular biology.

Structure and Reactivity of Transferrins

E. Baker, 1994 .

Metal substitution in transferrins: specific binding of cerium(IV) revealed by the crystal structure of cerium-substituted human lactoferrin

H. Baker, E. Baker, Clyde A. Smith, 2000, JBIC Journal of Biological Inorganic Chemistry.

Structure of XynB, a highly thermostable beta-1,4-xylanase from Dictyoglomus thermophilum Rt46B.1, at 1.8 A resolution.

E. Baker, A. McCarthy, P. Bergquist, 2000, Acta crystallographica. Section D, Biological crystallography.

Calcium-mediated thermostability in the subtilisin superfamily: the crystal structure of Bacillus Ak.1 protease at 1.8 A resolution.

H. Baker, E. Baker, C. Smith, 1999, Journal of molecular biology.

The Extracellular Protein Factor Epf from Streptococcus pyogenes Is a Cell Surface Adhesin That Binds to Cells through an N-terminal Domain Containing a Carbohydrate-binding Module*

J. Whisstock, E. Baker, M. Radjainia, 2012, The Journal of Biological Chemistry.

Blue copper proteins. The copper site in azurin from Alcaligenes denitrificans

E. Baker, B. Anderson, G. Norris, 1986 .

Copper co-ordination to thioether ligands. Chemical, spectroscopic, and crystallographic studies on copper(I) complexes of 2-(3,3-dimethyl-2-thiabutyl)pyridine and the 2-(3,3-dimethyl-2-thiabutyl)pyridinium cation

E. Baker, N. Larsen, E. Ainscough, 1981 .

Copper co-ordination to thioether ligands. Spectroscopic studies of dimeric copper(II) complexes of 2-(3,3-dimethyl-2-thiabutyl)pyridine and the crystal structure of di-µ-bromo-bis{bromo[2-(3,3-dimethyl-2-thiabutyl)pyridine-NS]copper(II)}

E. Baker, N. Larsen, E. Ainscough, 1981 .

Spectrochemical studies on the blue copper protein azurin from Alcaligenes denitrificans.

H. Gray, E. Baker, G. Norris, 1987, Biochemistry.

Copper co-ordination to thioether ligands: crystal and molecular structures of bis(2,5-dithiahexane)copper(II) bis(tetrafluoroborate) and bis(3,6-dithiaoctane)copper(I) tetrafluoroborates

E. Baker, G. Norris, 1977 .

Conformational influences in copper co-ordination compounds. Part II. Crystal structure of the methylammonium perchlorate adduct of NN′-ethylenebis(acetylacetoneiminato)copper(II)

E. Baker, D. Hall, T. Waters, 1970 .

Conformational influences in copper co-ordination compounds. Part III. Crystal structure of the p-nitrophenol adduct of NN′-ethylenebis(salicylideneiminato)copper(II)

E. Baker, D. Hall, T. Waters, 1970 .

Copper(II)-promoted oxidation of mercaptocarboxylic acids. The characterization of disulphide- and oxalate-containing products. Crystal structures of [{Cu(bipy)(2,2′-dtdp)}n]·3nH2O and [{Cu(bipy)(3,3′-dtdp)}n]·2nH2O (bipy = 2,2′-bipyridine, dtdp = dithiodipropanoate)

E. Baker, M. Brader, David A. Lewandoski, 1990 .

The colour isomerism and structure of some copper co-ordination compounds. Part XIII. Crystal structure of bis-(N-ethylsalicylaldiminato)copper(II)

E. Baker, G. Clark, D. Hall, 1967 .

Structure of azurin from Alcaligenes denitrificans refinement at 1.8 A resolution and comparison of the two crystallographically independent molecules.

E N Baker, E. Baker, 1987, Journal of molecular biology.

Folate-binding triggers the activation of folylpolyglutamate synthetase.

E N Baker, C A Smith, E. Baker, 2001, Journal of molecular biology.

Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases.

W. Denny, E. Baker, A. M. Thompson, 2008, Bioorganic & medicinal chemistry letters.

Structure of azurin from Alcaligenes denitrificans at 2.5 A resolution.

B F Anderson, E N Baker, E. Baker, 1983, Journal of molecular biology.

Copper coordination geometry in azurin undergoes minimal change on reduction of copper(II) to copper(I)

Edward N. Baker, William Shepard, E. Baker, 1990 .

COPPER COORDINATION TO THIOETHER LIGANDS. SPECTROSCOPIC STUDIES OF DIMERIC COPPER(II) COMPLEXES OF 2-(3,3-DIMETHYL-2-THIABUTYL)PYRIDINE AND THE CRYSTAL STRUCTURE OF DI-μ-BROMOBIS(BROMO(2-(3,3-DIMETHYL-2-THIABUTYL)PYRIDINE-N,S)COPPER(I

E. Baker, N. Larsen, E. Ainscough, 1982 .

COPPER COORDINATION TO THIOETHER LIGANDS. CHEMICAL, SPECTROSCOPIC, AND CRYSTALLOGRAPHIC STUDIES ON COPPER(I) COMPLEXES OF 2-(3,3-DIMETHYL-2-THIOBUTYL)PYRIDINE AND THE 2-(3,3-DIMETHYL-2-THIOBUTYL)PYRIDINIUM CATION

E. Baker, N. Larsen, E. Ainscough, 1981 .

Copper promoted reactions of the heterocyclic thioamide, 2-thiazolidinethione

E. Baker, B. Anderson, G. Gainsford, 1985 .

Preliminary crystallographic studies of copper(II)- and oxalate-substituted human lactoferrin.

H. Baker, E. Baker, C. Smith, 1991, Journal of molecular biology.

Structure of human lactoferrin: crystallographic structure analysis and refinement at 2.8 A resolution.

D. Rice, H. Baker, E. Baker, 1989, Journal of molecular biology.

COPPER COORDINATION TO THIOETHER LIGANDS- CRYSTAL AND MOLECULAR STRUCTURES OF BIS(2,5-DITHIAHEXANE)COPPER(II) BIS(TETRAFLUOROBORATE) AND BIS(3,6-DITHIAOCTANE)COPPER(I) TETRAFLUOROBORATES

E. Baker, G. Norris, 1977 .

Copper(II)-Promoted Oxidation of Mercaptocarboxylic Acids. The Characterization of Disulfide- and Oxalate-Containing Products. Crystal Structures of ((Cu(bipy)(2,2′-dtdp))n)·3nH2O and ((Cu(bipy)(3,3′-dtdp))n)·2nH2O (bipy: 2,2′-Bipyrid

E. Baker, M. Brader, David A. Lewandoski, 1990 .

Chelation of nickel(II) by citrate. The crystal structure of a nickel–citrate complex, K2[Ni(C6H5O7)(H2O)2]2·4H2O

H. Baker, E. Baker, B. Anderson, 1983 .

Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.

E N Baker, E. Baker, P. Jeffrey, 1999, Structure.

Crystal structure of Escherichia coli manganese superoxide dismutase at 2.1-Å resolution

J. W. Whittaker, H. Baker, E. Baker, 1998, JBIC Journal of Biological Inorganic Chemistry.

Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.

H. Baker, E. Baker, F. Coulibaly, 2012, Acta crystallographica. Section D, Biological crystallography.

Structural homologies with ATP- and folate-binding enzymes in the crystal structure of folylpolyglutamate synthetase.

E. Baker, C. Smith, A. Bognar, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Metal substitution in transferrins: the crystal structure of human copper-lactoferrin at 2.1-A resolution.

H. Baker, E. Baker, B. Anderson, 1992, Biochemistry.

Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelain.

I. G. Kamphuis, J. Drenth, E. Baker, 1985, Journal of molecular biology.

Structure of actinidin, after refinement at 1.7 A resolution.

E N Baker, E. Baker, 1980, Journal of molecular biology.

Acta crystallographica section E : Structure reports online

Howard M. Einspahr, J. Mitchell Guss, William Clegg, 2008 .

Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU).

E. Baker, R. Payne, D. Wen, 2013, Organic & biomolecular chemistry.

Lactoferrin Is a Potent Regulator of Bone Cell Activity and Increases Bone Formation in Vivo

Edward N Baker, Jillian Cornish, Dorit Naot, 2022 .

Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism

Edward N Baker, E. Baker, G. Cooper, 2006, Proceedings of the National Academy of Sciences.

Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism*

E. Baker, E. M. Bulloch, R. D. Bunker, 2012, The Journal of Biological Chemistry.

Pili in Gram-negative and Gram-positive bacteria — structure, assembly and their role in disease

E. Baker, T. Proft, 2009, Cellular and Molecular Life Sciences.

Structural basis of the Tanford transition of bovine beta-lactoglobulin.

E N Baker, B. Qin, H. Baker, 1998, Biochemistry.

A revised biosynthetic pathway for the cofactor F420 in prokaryotes

N. Tokuriki, E. Baker, B. Palmer, 2019, Nature Communications.

Elongation of the Poly-γ-glutamate Tail of F420 Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis*

H. Baker, E. Baker, G. Bashiri, 2016, The Journal of Biological Chemistry.

Metabolic Engineering of Cofactor F420 Production in Mycobacterium smegmatis

E. Baker, D. Greenwood, G. Bashiri, 2010, PloS one.

Crystal Structures of F420-dependent Glucose-6-phosphate Dehydrogenase FGD1 Involved in the Activation of the Anti-tuberculosis Drug Candidate PA-824 Reveal the Basis of Coenzyme and Substrate Binding*

E. Baker, G. Bashiri, N. Moreland, 2008, Journal of Biological Chemistry.

Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system.

E. Baker, G. Bashiri, N. Moreland, 2007, Protein expression and purification.

A revised biosynthetic pathway for the cofactor F420 in bacteria

N. Tokuriki, E. Baker, B. Palmer, 2018, bioRxiv.

Investigating the Reaction Mechanism of F420-Dependent Glucose-6-phosphate Dehydrogenase from Mycobacterium tuberculosis: Kinetic Analysis of the Wild-Type and Mutant Enzymes.

E. Baker, Mercy A Oyugi, G. Bashiri, 2016, Biochemistry.

Functional implications of structural differences between variants A and B of bovine β‐lactoglobulin

B. Qin, E. Baker, M. Bewley, 2008, Protein science : a publication of the Protein Society.

Structure of actinidin: details of the polypeptide chain conformation and active site from an electron density map at 2-8 A resolution.

E. Baker, 1977, Journal of molecular biology.

A non‐synonymous nucleotide substitution can account for one evolutionary route to sesquiterpene synthase activity in the TPS‐b subgroup

E. Baker, W. Laing, S. Green, 2011, FEBS letters.

The structure of truncated recombinant human bile salt-stimulated lipase reveals bile salt-independent conformational flexibility at the active-site loop and provides insights into heparin binding.

H. Baker, E. Baker, S. Moore, 2001, Journal of molecular biology.

Mechanistic insights into F420-dependent glucose-6-phosphate dehydrogenase using isotope effects and substrate inhibition studies.

E. Baker, Mercy A Oyugi, G. Bashiri, 2018, Biochimica et biophysica acta. Proteins and proteomics.

Tat–Dependent Translocation of an F420–Binding Protein of Mycobacterium tuberculosis

E. Baker, M. Braunstein, Meghan E. Feltcher, 2012, PloS one.

Crystal structure of the NADP(H)-dependent ketose reductase from Bemisia argentifolii at 2.3 A resolution.

E. Baker, C. Smith, M. Banfield, 2001, Journal of molecular biology.

Crystallographic data for human lactoferrin.

E. Baker, S. Rumball, Edward N. Baker, 1977, Journal of molecular biology.

Crystal structures of the staphylococcal toxin SSL5 in complex with sialyl Lewis X reveal a conserved binding site that shares common features with viral and bacterial sialic acid binding proteins.

H. Baker, E. Baker, J. Fraser, 2007, Journal of molecular biology.

Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium tuberculosis Reveal a Novel Bound Nucleotide*

E. Baker, E. M. Bulloch, D. Greenwood, 2011, The Journal of Biological Chemistry.

Purification and characterization of Ak.1 protease, a thermostable subtilisin with a disulphide bond in the substrate-binding cleft.

E. Baker, C. Smith, H. Toogood, 2000, The Biochemical journal.

Molecular structure, binding properties and dynamics of lactoferrin.

H. Baker, E. Baker, Edward N. Baker, 2005, Cellular and molecular life sciences : CMLS.

Histidine phosphorylation in biological systems.

L. Delbaere, E. Baker, Jennifer Puttick, 2008, Biochimica et biophysica acta.

Visualizing an unseen enemy; mobilizing structural biology to counter COVID-191

E. Baker, 2020, Acta crystallographica. Section F, Structural biology communications.

Crystal and molecular structure of pentacarbonyl(trimethylphosphine sulphide)chromium(0)

E. Baker, B. Reay, 1974 .

Lactoferrin and Iron: structural and dynamic aspects of binding and release

H. Baker, E. Baker, 2004, Biometals.

Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypical tyrosine kinase with a key role in CDK1 regulation.

E. Baker, C. Squire, J. Dickson, 2005, Structure.

Apolactoferrin structure demonstrates ligand-induced conformational change in transferrins

Edward N. Baker, Sylvia V. Rumball, H. Baker, 1990, Nature.

Structure of human diferric lactoferrin refined at 2.2 A resolution.

B F Anderson, E N Baker, E. Baker, 1995, Acta crystallographica. Section D, Biological crystallography.

Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution.

E. Baker, B. Anderson, C. Day, 1993, Journal of molecular biology.

The structure of glucose-fructose oxidoreductase from Zymomonas mobilis: an osmoprotective periplasmic enzyme containing non-dissociable NADP.

E. Baker, R. Scopes, R. Kingston, 1996, Structure.

Crystal structures of the precursor form of glucose-fructose oxidoreductase from Zymomonas mobilis and its complexes with bound ligands.

G. Sprenger, D. Nurizzo, E. Baker, 2001, Biochemistry.

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology.

A W Munro, M Wilmanns, E N Baker, 2003, Tuberculosis.

Dealing with iron: Common structural principles in proteins that transport iron and heme

H. Baker, E. Baker, B. Anderson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

12‐Bromododecanoic acid binds inside the calyx of bovine β‐lactoglobulin

B. Qin, E. Baker, G. Jameson, 1998 .

Three-dimensional structure and ligand binding properties of trichosurin, a metatherian lipocalin from the milk whey of the common brushtail possum Trichosurus vulpecula.

V. Arcus, E. Baker, J. Demmer, 2007, The Biochemical journal.

Lactoferrin and transferrin: functional variations on a common structural framework.

Edward N Baker, H. Baker, E. Baker, 2002, Biochemistry and cell biology = Biochimie et biologie cellulaire.

A new Gateway vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis.

E. Baker, G. Bashiri, N. Moreland, 2008, Protein expression and purification.

Structure of Rhombohedral 2 Zinc Insulin Crystals

E. Baker, D. Hodgkin, M. Vijayan, 1969, Nature.

The chemistry of bis-spiroacetals. Synthesis of the novel 1,7,9-trioxadispiro[5.1.5.3]hexadecane ring system

E. Baker, M. Brimble, Geoffrey M. Williams, 1990 .

Structural and Functional Properties of Staphylococcal Superantigen-Like Protein 4

H. Baker, E. Baker, Richard P Sequeira, 2012, Infection and Immunity.

The crystal structure of aminoglycoside-3'-phosphotransferase-IIa, an enzyme responsible for antibiotic resistance.

Edward N Baker, Didier Nurizzo, Taru Deva, 2003, Journal of molecular biology.

Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.

E. Baker, Zhening Zhang, T. Caradoc-Davies, 2009, Journal of molecular biology.

Data archiving and availability in an era of open science

Edward N. Baker, E. Baker, 2017, IUCrJ.

Serological Evidence of Immune Priming by Group A Streptococci in Patients with Acute Rheumatic Fever

E. Baker, T. Proft, P. Young, 2016, Front. Microbiol..

The specificity of actinidin and its relationship to the structure of the enzyme.

P. Calder, E. Baker, M. Boland, 1980, Biochimica et biophysica acta.

Structural and Functional Characterization of an RNase HI Domain from the Bifunctional Protein Rv2228c from Mycobacterium tuberculosis

E. Baker, Harriet A. Watkins, 2010, Journal of bacteriology.

Transferrins: insights into structure and function from studies on lactoferrin

E. Baker, B. Anderson, S. Rumball, 1987 .

Intramolecular isopeptide bonds: protein crosslinks built for stress?

E. Baker, H. Kang, 2011, Trends in biochemical sciences.

Crystal structure of a truncated mutant of glucose-fructose oxidoreductase shows that an N-terminal arm controls tetramer formation.

G. Sprenger, H. Baker, E. Baker, 2000, Journal of molecular biology.

The crystal structure of staphylococcal superantigen‐like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition

H. Baker, E. Baker, J. Fraser, 2007, Molecular microbiology.

Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP

E. Baker, P. Young, Clyde A. Smith, 2008, Acta crystallographica. Section D, Biological crystallography.

Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease.

J. Musser, H. Baker, E. Baker, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release.

Q. He, R. MacGillivray, A. Mason, 2000, Biochemistry.

Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.

D. Nurizzo, H. Baker, A. Mason, 2007, Acta crystallographica. Section D, Biological crystallography.

Structure of a domain-opened mutant (R121D) of the human lactoferrin N-lobe refined from a merohedrally twinned crystal form.

E. Baker, B. Anderson, G. Jameson, 2002, Acta crystallographica. Section D, Biological crystallography.

Superantigens - powerful modifiers of the immune system.

V. Arcus, E. Baker, T. Proft, 2000, Molecular medicine today.

The Crystal Structures of Substrate and Nucleotide Complexes of Enterococcus faecium Aminoglycoside-2′′-Phosphotransferase-IIa [APH(2′′)-IIa] Provide Insights into Substrate Selectivity in the APH(2′′) Subfamily

E. Baker, L. Byrnes, P. Young, 2009, Journal of bacteriology.

The Crystal Structures of Substrate and Nucleotide Complexes of Enterococcus faecium Aminoglycoside-2 (cid:2)(cid:2) -Phosphotransferase-IIa [APH(2 (cid:2)(cid:2) )-IIa] Provide Insights into Substrate Selectivity in the APH(2 (cid:2)(cid:2) ) Subfamily (cid:1) ‡

E. Baker, L. Byrnes, P. Young, 2009 .

Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis.

E. Baker, G. Jameson, E. Parker, 2013, Journal of molecular biology.

Crystallographic and Mutational Data Show That the Streptococcal Pyrogenic Exotoxin J Can Use a Common Binding Surface for T-cell Receptor Binding and Dimerization*

V. Arcus, H. Baker, E. Baker, 2004, Journal of Biological Chemistry.

1.8 A crystal structure of the C-terminal domain of rabbit serum haemopexin.

H. R. Faber, C. Groom, H. Baker, 1995, Structure.

Inhibition of Indigoidine Synthesis as a High-Throughput Colourimetric Screen for Antibiotics Targeting the Essential Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT

Alistair S Brown, E. Baker, D. Ackerley, 2021, Pharmaceutics.

Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein.

Alistair S Brown, E. Baker, J. Johnston, 2014, Journal of structural biology.

Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change.

B F Anderson, E N Baker, E. Baker, 1998, Acta crystallographica. Section D, Biological crystallography.

A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket.

E. Baker, J. Johnston, E. M. Bulloch, 2015, Acta crystallographica. Section D, Biological crystallography.

Mutagenesis of Human Lactoferrin and Expression in Baby Hamster Kidney Cells

H. Nicholson, E. Baker, C. Day, 1997 .

Cloning and expression of the C-terminal lobe of human lactoferrin.

E. Baker, C. Day, B. Sheth, 1994, Advances in experimental medicine and biology.

Selected and Directed Mutants of T4 Phage Lysozyme

B. Matthews, J. A. Wozniak, E. Baker, 1987 .

Crystallization and preliminary diffraction studies of the C-terminal domain of the DipZ homologue from Mycobacterium tuberculosis.

E. Baker, D. Goldstone, P. Metcalf, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis.

E. Baker, C. Squire, N. Koon, 2004, Proceedings of the National Academy of Sciences of the United States of America.

X-ray crystallographic studies of seal myoglobin

E. Baker, H. Scouloudi, 1978 .

X-ray crystallographic studies of seal myoglobin. The molecule at 2.5 A resolution.

E N Baker, E. Baker, H Scouloudi, 1969, Journal of molecular biology.

The structure of actinidin at 5-5 A resolution.

E. Baker, 1976, Journal of molecular biology.

The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase

E. Baker, J. Lott, Minmin Yu, 2006, Journal of bacteriology.

Complex Formation between Two Biosynthetic Enzymes Modifies the Allosteric Regulatory Properties of Both

Edward N Baker, Emily J Parker, E. Baker, 2015, The Journal of Biological Chemistry.

Structural and functional similarities in the ADP-forming amide bond ligase superfamily: implications for a substrate-induced conformational change in folylpolyglutamate synthetase.

E. Baker, C. Smith, Y. Sheng, 2000, Journal of molecular biology.

Structure of recombinant human lactoferrin expressed in Aspergillus awamori.

H. Baker, E. Baker, G. Jameson, 1999, Acta crystallographica. Section D, Biological crystallography.

Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases.

H. Baker, E. Baker, S. Moore, 1998, Structure.

Distant Structural Homology Leads to the Functional Characterization of an Archaeal PIN Domain as an Exonuclease*

V. Arcus, E. Baker, A. Roos, 2004, Journal of Biological Chemistry.

Structure of the Full-Length Major Pilin from Streptococcus pneumoniae: Implications for Isopeptide Bond Formation in Gram-Positive Bacterial Pili

E. Baker, N. Paterson, 2011, PloS one.

Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation

E. Baker, C. Day, J. Lott, 2014, Molecular microbiology.

Crystal Structure of PhnF, a GntR-Family Transcriptional Regulator of Phosphate Transport in Mycobacterium smegmatis

E. Baker, J. Lott, G. Fritz, 2014, Journal of bacteriology.

A structural explanation for the retinal specificity of class 1 ALDH enzymes.

H. Baker, E. Baker, S. Moore, 1999, Advances in experimental medicine and biology.

The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes.

H. Baker, E. Baker, E. Parker, 2005, Journal of molecular biology.

Crystallization and preliminary X-ray crystallographic analysis of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Mycobacterium tuberculosis.

Edward N Baker, Emily J Parker, H. Baker, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.

J. W. Whittaker, E. Baker, G. Jameson, 2001, Biochemistry.

Electron transfer between cytochrome b(5) and some oxidised haemoglobins: the role of ionic strength.

E. Baker, R. Kidd, T. Brittain, 2002, Journal of inorganic biochemistry.

Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two β-propeller domains

Edward N. Baker, William T. Morgan, Massimo Paoli, 1999, Nature Structural Biology.

The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis*

E. Baker, J. Lott, Chen Gao, 2016, The Journal of Biological Chemistry.

The Structure of an Ancient Conserved Domain Establishes a Structural Basis for Stable Histidine Phosphorylation and Identifies a New Family of Adenosine-specific Kinases*

L. Delbaere, E. Baker, J. Johnston, 2006, Journal of Biological Chemistry.

Crystal structure of MshB from Mycobacterium tuberculosis, a deacetylase involved in mycothiol biosynthesis.

Edward N Baker, Andrew A McCarthy, E. Baker, 2004, Journal of molecular biology.

Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization

E. Baker, M. Brimble, P. Young, 2016, IUCrJ.

Crystallographic studies on metal and anion substituted human lactoferrin.

H. Baker, E. Baker, B. Anderson, 1994, Advances in experimental medicine and biology.

Identification of an immunodominant region on a group A Streptococcus T-antigen reveals temperature-dependent motion in pili

E. Baker, T. Proft, P. Young, 2023, Virulence.

Structure of Escherichia coli UDP-N-acetylmuramoyl:L-alanine ligase (MurC).

E. Baker, Clyde A. Smith, C. Squire, 2006, Acta crystallographica. Section D, Biological crystallography.

Search designs for protein crystallization based on orthogonal arrays.

E N Baker, H. Baker, E. Baker, 1994, Acta crystallographica. Section D, Biological crystallography.

Subunit dissociation and reassociation leads to preferential crystallization of haemoglobin Bart's (γ4) from solutions of human embryonic haemoglobin Portland (ζ2γ2) at low pH

H. Baker, E. Baker, A. Mathews, 2001 .

Crystal structure of a human embryonic haemoglobin: the carbonmonoxy form of gower II (alpha2 epsilon2) haemoglobin at 2.9 A resolution.

H. Baker, E. Baker, A. Sutherland-Smith, 1998, Journal of molecular biology.

Search Designs for Protein Crystallization Based on

H. Baker, E. Baker, R. Kingston, 1994 .

Crystallographic refinement of the structure of actinidin at 1.7 Å resolution by fast Fourier least‐squares methods

E. Baker, E. Dodson, E. J. Dodson, 1980 .

The TB structural genomics consortium: providing a structural foundation for drug discovery.

Shekhar C Mande, Tom Alber, David Eisenberg, 2002, Current drug targets. Infectious disorders.

The potential impact of structural genomics on tuberculosis drug discovery.

Edward N Baker, Vickery L Arcus, V. Arcus, 2006, Drug discovery today.

From Penicillin to the Ribosome: Revolutions in the Determination and Use of Molecular Structure in Chemistry and Biology

E. Baker, 2004 .

Stress control for a well-structured life

E. Baker, D. Goldstone, 2018, The Journal of Biological Chemistry.

"Dilysine trigger" in transferrins probed by mutagenesis of lactoferrin: crystal structures of the R210G, R210E, and R210L mutants of human lactoferrin.

V. Arcus, E. Baker, B. Anderson, 2002, Biochemistry.

Crystal structure of a sigma 28-regulated non-flagella virulence protein from campylobacter jejuni

E. Goldsmith, M. Perbandt, C. Betzel, 2008 .

Crystal structure of the protein disulfide bond isomerase, DsbC, from Escherichia coli

V. Rybin, E. Baker, A. McCarthy, 2000, Nature Structural Biology.

Potent Inhibitors of a Shikimate Pathway Enzyme from Mycobacterium tuberculosis

E. Baker, E. Parker, W. Jiao, 2011, The Journal of Biological Chemistry.

Crystal Structure of Spy0129, a Streptococcus pyogenes Class B Sortase Involved in Pilus Assembly

E. Baker, T. Proft, H. Kang, 2011, PloS one.

Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis.

E. Baker, J. Johnston, E. M. Bulloch, 2012, Biochemistry.

Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes.

V. Arcus, H. Baker, E. Baker, 2000, Journal of molecular biology.

Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin.

H. Baker, A. Mason, E. Baker, 2003, Biochemistry.

Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI)

E. Baker, E. M. Bulloch, R. Payne, 2010, ChemMedChem.

Structural Views along the Mycobacterium tuberculosis MenDReaction Pathway Illuminate Key Aspects of ThiaminDiphosphate-Dependent EnzymeMechanisms Graphical

E. Baker, J. Johnston, E. M. Bulloch, 2016 .

Widening the reach of structural biology

E. Baker, 2016, IUCrJ.

Characterization of the proline-utilization pathway in Mycobacterium tuberculosis through structural and functional studies.

E. Baker, M. Berney, N. Paterson, 2014, Acta crystallographica. Section D, Biological crystallography.

Crystal Structure of the Minor Pilin FctB Reveals Determinants of Group A Streptococcal Pilus Anchoring*

E. Baker, C. Linke, T. Proft, 2010, The Journal of Biological Chemistry.

High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon.

Edward N Baker, J. Oakeshott, R. Russell, 2007, Biochemistry.

Binding of ruthenium(III) anti-tumor drugs to human lactoferrin probed by high resolution X-ray crystallographic structure analyses

E. Baker, B. Keppler, F. Kratz, 1996, JBIC Journal of Biological Inorganic Chemistry.

The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate.

E. Baker, F. Javid-Majd, Catherine E. Goodfellow, 2006, Journal of molecular biology.

Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies

E. Baker, G. Bashiri, 2015, Protein science : a publication of the Protein Society.

Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding.

H. Baker, E. Baker, E. Parker, 2012, Biochemistry.

Surface Proteins of Gram-Positive Pathogens: Using Crystallography to Uncover Novel Features in Drug and Vaccine Candidates

E. Baker, T. Proft, H. Kang, 2009 .

Structural genomics as an approach towards understanding the biology of tuberculosis

E. Baker, 2007, Journal of Structural and Functional Genomics.

A revised biosynthetic pathway for the cofactor F420 in prokaryotes

N. Tokuriki, E. Baker, B. Palmer, 2019, Nature Communications.

Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis*

H. Baker, E. Baker, G. Jameson, 2010, The Journal of Biological Chemistry.

Immunological and Biochemical Characterization of Streptococcal Pyrogenic Exotoxins I and J (SPE-I and SPE-J) from Streptococcus pyogenes1

V. Arcus, E. Baker, T. Proft, 2001, The Journal of Immunology.

Altered domain closure and iron binding in transferrins: the crystal structure of the Asp60Ser mutant of the amino-terminal half-molecule of human lactoferrin.

H. R. Faber, E. Baker, G. Norris, 1996, Journal of molecular biology.

Studies of the N-terminal half of human lactoferrin produced from the cloned cDNA demonstrate that interlobe interactions modulate iron release.

E. Baker, C. Day, J. Tweedie, 1992, The Journal of biological chemistry.

Molecular replacement solution of the structure of apolactoferrin, a protein displaying large-scale conformational change.

B F Anderson, E N Baker, E. Baker, 1991, Acta crystallographica. Section B, Structural science.

Altered Domain Closure and Iron Binding in Lactoferrin Mutants

H. Nicholson, H. R. Faber, H. Baker, 1997 .

Why conferences matter – musings from a crystallographic meeting

Edward N. Baker, E. Baker, 2019, IUCrJ.

Metal substitution in a blue-copper protein: the crystal structure of cadmium-azurin at 1.8 A resolution.

E. Baker, B. F. Andersen, K. A. Blackwell, 1994, Acta Crystallographica Section D: Biological Crystallography.

Biological crystallography: new methods, new challenges

Edward N. Baker, E. Baker, 2015, IUCrJ.

Enzymatic deglycosylation as a tool for crystallization of mammalian binding proteins.

H. Baker, E. Baker, G. Norris, 1994, Acta crystallographica. Section D, Biological crystallography.

Human melanotransferrin (p97) has only one functional iron‐binding site

H. Baker, E. Baker, M. Kahn, 1992, FEBS letters.

Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.

H. R. Faber, E. Baker, C. Baker, 1996, Biochemistry.

Structural and Functional Flexibility of Lactoferrin

H. R. Faber, H. Baker, E. Baker, 1997 .

Crystal Structure of Epiphyas postvittana Takeout 1

E. Baker, R. Newcomb, D. Greenwood, 2008 .

Crystal structure and iron-binding properties of the R210K mutant of the N-lobe of human lactoferrin: implications for iron release from transferrins.

E. Baker, B. Anderson, G. Jameson, 2000, Biochemistry.

Mutagenesis of the histidine ligand in human lactoferrin: iron binding properties and crystal structure of the histidine-253-->methionine mutant.

H. Nicholson, E. Baker, B. Anderson, 1997, Biochemistry.

Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin

E. Baker, P. Young, H. Kwon, 2013, Proceedings of the National Academy of Sciences.

Isopeptide bonds in bacterial pili and their characterization by X‐ray crystallography and mass spectrometry

E. Baker, T. Proft, H. Kang, 2009, Biopolymers.

X-ray diffraction data on some crystalline varieties of insulin.

E. Baker, G. Dodson, 1970, Journal of molecular biology.

Crystal Structure of LeuA from Mycobacterium tuberculosis

E. Baker, C. Squire, N. Koon, 2004 .

Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin.

Edward N Baker, Brent W Segelke, Li-Wei Hung, 2005, Journal of molecular biology.

Self-generated covalent cross-links in the cell-surface adhesins of Gram-positive bacteria.

E. Baker, P. Young, C. Squire, 2015, Biochemical Society transactions.

Intramolecular Isopeptide Bonds Give Thermodynamic and Proteolytic Stability to the Major Pilin Protein of Streptococcus pyogenes*

E. Baker, H. Kang, 2009, The Journal of Biological Chemistry.

The role of beta chains in the control of the hemoglobin oxygen binding function: chimeric human/mouse proteins, structure, and function.

E. Baker, R. Kidd, J. E. Russell, 2001, Biochemistry.

Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes.

H. Baker, E. Baker, Qing‐Yu He, 2009, Biochemistry.

Iron-ic twists of fate

E. Baker, 1997, Nature Structural Biology.

Removing a hydrogen bond in the dimer interface of Escherichia coli manganese superoxide dismutase alters structure and reactivity.

J. W. Whittaker, E. Baker, G. Jameson, 2001, Biochemistry.

Crystal structure of the streptococcal superantigen SPE-C: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules

H. Baker, E. Baker, B. Anderson, 1997, Nature Structural Biology.

A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography

E. Baker, J. Lott, S. Kent, 2015, Proceedings of the National Academy of Sciences.

Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis

E. Baker, J. Johnston, G. Bashiri, 2016, FEBS open bio.

A flexible and economical medium-throughput strategy for protein production and crystallization.

V. Arcus, H. Baker, E. Baker, 2005, Acta crystallographica. Section D, Biological crystallography.

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex.

E. Baker, J. Johnston, E. M. Bulloch, 2015, Acta crystallographica. Section D, Biological crystallography.

The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition.

E. Baker, E. Parker, E. M. Bulloch, 2013, Biochemistry.

Protein structure prediction and analysis as a tool for functional genomics.

Edward N Baker, Vickery L Arcus, V. Arcus, 2003, Applied bioinformatics.

Crystallization and preliminary X-ray analysis of N-acetyl-1-D-myo-inosityl-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis.

E. Baker, A. McCarthy, N. A. Peterson, 2003, Acta crystallographica. Section D, Biological crystallography.

Specific binding of cerium by human lactoferrin stimulates the oxidation of Ce3+ to Ce4+

H. Baker, E. Baker, Clyde A. Smith, 1994 .

Distinct Metal Environment in Fe-Substituted Manganese Superoxide Dismutase Provides a Structural Basis of Metal Specificity

J. W. Whittaker, E. Baker, G. Jameson, 1998 .

Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms.

E. Baker, J. Johnston, E. M. Bulloch, 2016, Structure.

Crystallography and the development of therapeutic medicines

Edward N. Baker, E. Baker, 2018, IUCrJ.

Seeing Atoms: The Rise and Rise of Crystallography in Chemistry and Biology

E. Baker, 2011 .

III.1 - Bovine β-lactoglobulin and its variants : A three-dimensional structural perspective

B. Qin, E. Baker, M. Bewley, 1997 .

Interaction of benzo-1,3-thiazoline-2-thione and related ligands with copper(II) salts and the single-crystal X-ray structure of µ-[1,2-bis-(diphenylphosphino)ethane]-bis{(benzo-1,3-thiazole-2-thiolato-S)[1,2-bis(diphenylphosphinoethane]copper(I)}

E. Baker, Clyde A. Smith, E. Ainscough, 1989 .

Cloning, expression, purification and preliminary crystallographic analysis of the RNase HI domain of the Mycobacterium tuberculosis protein Rv2228c as a maltose-binding protein fusion.

E. Baker, Harriet A. Watkins, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Cloning, expression, purification and preliminary crystallographic data for Rv3214 (EntD), a predicted cofactor-dependent phosphoglycerate mutase from Mycobacterium tuberculosis.

E. Baker, Minmin Yu, Harriet A. Watkins, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization of a protein using dehydration without a precipitant.

E. Baker, J. Lott, M. Sharpe, 2005, Acta Crystallographica. Section F : Structural Biology and Crystallization Communications.

Crystallization and preliminary X-ray crystallographic analysis of MbtI, a protein essential for siderophore biosynthesis in Mycobacterium tuberculosis.

E. Baker, J. Lott, R. J. Ramsay, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure and function of GlmU from Mycobacterium tuberculosis.

E. Baker, E. M. Bulloch, R. D. Bunker, 2009, Acta crystallographica. Section D, Biological crystallography.

Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.

E. Baker, E. Parker, J. Lott, 2015, Biochemistry.

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.

E. Baker, E. Parker, E. M. Bulloch, 2014, The Biochemical journal.

Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups

E. Baker, E. Parker, J. Lott, 2017, Data in brief.

Structural and Functional Analysis of Rv3214 from Mycobacterium tuberculosis, a Protein with Conflicting Functional Annotations, Leads to Its Characterization as a Phosphatase

E. Baker, Harriet A. Watkins, 2006, Journal of bacteriology.

Purification, crystallization and preliminary crystallographic analysis of the adhesion domain of Epf from Streptococcus pyogenes.

E. Baker, B. Kreikemeyer, C. Linke, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

The Structure of a Putative Scaffolding Protein of Immature Poxvirus Particles as Determined by Electron Microscopy Suggests Similarity with Capsid Proteins of Large Icosahedral DNA Viruses

E. Baker, A. Mitra, A. Mercer, 2007, Journal of Virology.

Vitamin content of some normal human brain segments

E. Baker, O. Frank, H. Baker, 1984, Journal of neuroscience research.

A slow-forming isopeptide bond in the structure of the major pilin SpaD from Corynebacterium diphtheriae has implications for pilus assembly

Chae Un Kim, E. Baker, N. Paterson, 2014, Acta crystallographica. Section D, Biological crystallography.

AlphaFold and the future of structural biology.

R. Read, C. Bond, E. Baker, 2023, Acta crystallographica. Section D, Structural biology.

AlphaFold and the future of structural biology

R. Read, C. Bond, E. Baker, 2023, IUCrJ.

AlphaFold and the future of structural biology.

R. Read, C. Bond, E. Baker, 2023, Acta crystallographica. Section F, Structural biology communications.

Structure of the ectodomain of the electron transporter Rv2874 from Mycobacterium tuberculosis reveals a thioredoxin-like domain combined with a carbohydrate-binding module.

E. Baker, D. Goldstone, P. Metcalf, 2016, Acta crystallographica. Section D, Structural biology.

Crystal structure of SET3, a superantigen-like protein from Staphylococcus aureus

V. Arcus, E. Baker, T. Proft, 2002 .

Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases.

W. Denny, E. Lunney, E. Baker, 2008, European journal of medicinal chemistry.

Deposition of diffraction images to be discussed at the Open Meeting of the Commission on Biological Macromolecules of the IUCr in Osaka

Zbigniew Dauter, Edward Baker, Mitchell Guss, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Superoxide dismutases from hyperthermophiles: clues to metal-ion specificity

J. W. Whittaker, E. Baker, B. Anderson, 2003 .

Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo.

I. Reid, H. Baker, E. Baker, 2004, Endocrinology.

Biopolymers

E. Baker, D. Parry, 1984 .

Expectation bias and information content.

Z. Dauter, E. Baker, M. Weiss, 2013, Acta crystallographica. Section D, Biological crystallography.

PdxH proteins of mycobacteria are typical members of the classical pyridoxine/pyridoxamine 5′‐phosphate oxidase family

E. Baker, G. Bashiri, Karthik Ankisettypalli, 2016, FEBS letters.

Purification, crystallization and preliminary crystallographic analysis of Streptococcus pyogenes laminin-binding protein Lbp.

E. Baker, C. Linke, T. Proft, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

The Crystal Structure of Rv1347c, a Putative Antibiotic Resistance Protein from Mycobacterium tuberculosis, Reveals a GCN5-related Fold and Suggests an Alternative Function in Siderophore Biosynthesis*♦

Edward N Baker, Bernhard Rupp, B. Rupp, 2005, Journal of Biological Chemistry.

Cloning, expression, purification, crystallization and preliminary X-ray studies of the C-terminal domain of Rv3262 (FbiB) from Mycobacterium tuberculosis.

E. Baker, N. Paterson, G. Bashiri, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

X-ray crystallography and mass spectroscopy reveal that the N-lobe of human transferrin expressed in Pichia pastoris is folded correctly but is glycosylated on serine-32.

R. MacGillivray, A. Mason, R. Woodworth, 1999, Biochemistry.

Elongation of the Poly-γ-glutamate Tail of F420 Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis*

H. Baker, E. Baker, G. Bashiri, 2016, The Journal of Biological Chemistry.

Purification, crystallization and preliminary crystallographic analysis of the minor pilin FctB from Streptococcus pyogenes.

E. Baker, C. Linke, T. Proft, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Reveals Determinants of Group A Crystal Structure of the Minor Pilin FctB Protein Structure and Folding

E. Baker, T. Proft, R. D. Bunker, 2013 .

In defence of our science--validation now!

Z. Dauter, E. Baker, M. Weiss, 2010, Acta crystallographica. Section D, Biological crystallography.

In defence of our science – validation now!

Zbigniew Dauter, Howard Einspahr, Edward N. Baker, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

Janet Newman, Wladek Minor, Janos Hajdu, 2019, IUCrJ.

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

Janos Hajdu, Janet Newman, John R. Helliwell, 2019, Acta crystallographica. Section F, Structural biology communications.

Findable Accessible Interoperable Re-usable (FAIR) diffraction data are coming to protein crystallography

Janet Newman, John R Helliwell, Wladek Minor, 2019, Acta crystallographica. Section D, Structural biology.

Immunological and Biochemical Characterization of Streptococcal Pyrogenic Exotoxins I and J (SPE-I and SPE-J) from Streptococcus pyogenes1

V. Arcus, E. Baker, T. Proft, 2001, The Journal of Immunology.

Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis*

H. Baker, E. Baker, G. Jameson, 2010, The Journal of Biological Chemistry.

Hydrogen bonding in biological macromolecules

E. Baker, E. N. Baker, 2006 .

Crystallization and preliminary X-ray analysis of native and recombinant human bile-salt dependent lipase: strategies for improvement of diffraction quality.

H. Baker, E. Baker, O. Hernell, 2000, Acta Crystallographica Section D: Biological Crystallography.

Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism*

E. Baker, E. M. Bulloch, R. D. Bunker, 2012, The Journal of Biological Chemistry.

Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.

E. Baker, E. Parker, J. Lott, 2015, Biochemistry.

Three-dimensional structure and ligand binding properties of trichosurin, a metatherian lipocalin from the milk whey of the common brushtail possum Trichosurus vulpecula.

V. Arcus, E. Baker, J. Demmer, 2007, The Biochemical journal.

Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation

E. Baker, C. Day, J. Lott, 2014, Molecular microbiology.

Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.

E. Baker, Zhening Zhang, T. Caradoc-Davies, 2009, Journal of molecular biology.

Synergism and substitution in the lactoferrins.

H. Baker, E. Baker, C. Smith, 1994, Advances in experimental medicine and biology.

Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein.

Alistair S Brown, E. Baker, J. Johnston, 2014, Journal of structural biology.