M. Winkler

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Phenotypic Landscape of a Bacterial Cell

N. Krogan, M. Shales, C. Gross, 2011, Cell.

Kinetic Characterization of the WalRKSpn (VicRK) Two-Component System of Streptococcus pneumoniae: Dependence of WalKSpn (VicK) Phosphatase Activity on Its PAS Domain

M. Winkler, Alina D. Gutu, Kyle J. Wayne, 2010, Journal of bacteriology.

The Brucella abortus Cu,Zn Superoxide Dismutase Is Required for Optimal Resistance to Oxidative Killing by Murine Macrophages and Wild-Type Virulence in Experimentally Infected Mice

M. Winkler, R. Roop, M. Valderas, 2005, Infection and Immunity.

Biochemical reconstitution defines new functions for membrane-bound glycosidases in assembly of the bacterial cell wall

M. Winkler, S. Walker, A. Taguchi, 2021, Proceedings of the National Academy of Sciences.

Transcriptional Regulation and Signature Patterns Revealed by Microarray Analyses of Streptococcus pneumoniae R6 Challenged with Sublethal Concentrations of Translation Inhibitors

Wai-Leung Ng, K. Kazmierczak, M. Winkler, 2003, Journal of bacteriology.

Biosynthesis of Histidine.

M. Winkler, Smirla Ramos-Montañez, Malcolm E Winkler, 2009, EcoSal Plus.

Structural analysis of the Escherichia coli K-12 hisT operon by using a kanamycin resistance cassette

M. Winkler, P. J. Arps, 1987, Journal of bacteriology.

Characterization of broadly pleiotropic phenotypes caused by an hfq insertion mutation in Escherichia coli K‐12

M. Winkler, H. C. Tsui, H. Leung, 1994, Molecular microbiology.

Regulation of tryptophan biosynthesis in Caulobacter crescentus

C. M. Ross, M. Winkler, 1988, Journal of bacteriology.

Genome of the Bacterium Streptococcus pneumoniae Strain R6

Elliot J. Lefkowitz, Franklin H. Norris, Donald J. LeBlanc, 2001, Journal of bacteriology.

Metabolic relationships between pyridoxine (vitamin B6) and serine biosynthesis in Escherichia coli K-12

M. Winkler, H. Lam, M E Winkler, 1990, Journal of bacteriology.

An Escherichia coli K-12 tktA tktB mutant deficient in transketolase activity requires pyridoxine (vitamin B6) as well as the aromatic amino acids and vitamins for growth

M. Winkler, G. Zhao, M E Winkler, 1994, Journal of Bacteriology.

S1 Domain RNA-Binding Protein CvfD Is a New Posttranscriptional Regulator That Mediates Cold Sensitivity, Phosphate Transport, and Virulence in Streptococcus pneumoniae D39

J. Richardson, M. Winkler, H. C. Tsui, 2020, Journal of Bacteriology.

Seeking a niche: putative contributions of the hfq and bacA gene products to the successful adaptation of the brucellae to their intracellular home.

M. Winkler, G. Walker, R. Roop, 2002, Veterinary microbiology.

Biological and Chemical Adaptation to Endogenous Hydrogen Peroxide Production in Streptococcus pneumoniae D39

Kristy L. Hentchel, D. Giedroc, M. Winkler, 2017, mSphere.

Depletion of the cellular amounts of the MutS and MutH methyl-directed mismatch repair proteins in stationary-phase Escherichia coli K-12 cells

M. Winkler, H. C. Tsui, M E Winkler, 1996, Journal of bacteriology.

Transcriptional patterns of the mutL-miaA superoperon of Escherichia coli K-12 suggest a model for posttranscriptional regulation.

M. Winkler, H. C. Tsui, H. Tsui, 1994, Biochimie.

Absence of hisT-mediated tRNA pseudouridylation results in a uracil requirement that interferes with Escherichia coli K-12 cell division

M. Winkler, H. C. Tsui, P. J. Arps, 1991, Journal of Bacteriology.

Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39

Erin E. Carlson, S. Shaw, M. Winkler, 2013, Molecular microbiology.

Profiling of β-Lactam Selectivity for Penicillin-Binding Proteins in Streptococcus pneumoniae D39

Erin E. Carlson, M. Winkler, H. C. Tsui, 2015, Antimicrobial Agents and Chemotherapy.

Roles of relSpn in stringent response, global regulation and virulence of serotype 2 Streptococcus pneumoniae D39

A. Rechtsteiner, K. Kazmierczak, M. Winkler, 2009, Molecular microbiology.

A new quorum‐sensing system (TprA/PhrA) for Streptococcus pneumoniae D39 that regulates a lantibiotic biosynthesis gene cluster

M. Winkler, R. DiMarchi, B. Lazazzera, 2015, Molecular microbiology.

Genetic and physical analyses of Caulobacter crescentus trp genes

C. M. Ross, M. Winkler, B. Ely, 1984, Journal of bacteriology.

Nucleotide sequence of the Caulobacter crescentus flaF and flbT genes and an analysis of codon usage in organisms with G + C-rich genomes.

M. Winkler, B. Ely, P. Schoenlein, 1990, Gene.

The Requirement for Pneumococcal MreC and MreD Is Relieved by Inactivation of the Gene Encoding PBP1a

M. Winkler, Adrian D. Land, 2011, Journal of bacteriology.

Involvement of FtsE ATPase and FtsX Extracellular Loops 1 and 2 in FtsEX-PcsB Complex Function in Cell Division of Streptococcus pneumoniae D39

M. Winkler, Lok-To Sham, K. E. Bruce, 2013, mBio.

Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae

D. Giedroc, Hongwei Wu, M. Winkler, 2018, mBio.

Influences of Capsule on Cell Shape and Chain Formation of Wild-Type and pcsB Mutants of Serotype 2 Streptococcus pneumoniae

M. Winkler, Lok-To Sham, Wai-Leung Ng, 2009, Journal of bacteriology.

Structure oftheCaulobacter crescentus trpFBAOperon

C. M. Ross, M. Winkler, 1988 .

The Opp (AmiACDEF) Oligopeptide Transporter Mediates Resistance of Serotype 2 Streptococcus pneumoniae D39 to Killing by Chemokine CXCL10 and Other Antimicrobial Peptides

M. Winkler, H. C. Tsui, K. E. Bruce, 2018, Journal of bacteriology.

Chemical tools for selective activity profiling of bacterial penicillin-binding proteins.

Erin E. Carlson, M. Winkler, K. E. Bruce, 2020, Methods in enzymology.

Essentiality of clpX, but Not clpP, clpL, clpC, or clpE, in Streptococcus pneumoniae R6

M. Winkler, G. Robertson, Wai-Leung Ng, 2003, Journal of bacteriology.

Minimal Peptidoglycan (PG) Turnover in Wild-Type and PG Hydrolase and Cell Division Mutants of Streptococcus pneumoniae D39 Growing Planktonically and in Host-Relevant Biofilms

M. Winkler, E. Kuru, M. VanNieuwenhze, 2015, Journal of bacteriology.

Novel Electrophilic Scaffold for Imaging of Essential Penicillin-Binding Proteins in Streptococcus pneumoniae.

Erin E. Carlson, M. Winkler, Ozden Kocaoglu, 2017, ACS chemical biology.

Interplay between manganese and zinc homeostasis in the human pathogen Streptococcus pneumoniae.

D. Giedroc, K. Kazmierczak, M. Winkler, 2011, Metallomics : integrated biometal science.

Identification, sequencing, and enzymatic activity of the erythrose-4-phosphate dehydrogenase gene of Vibrio cholerae

M. Winkler, S. Calderwood, G. Zhao, 1997, Journal of Bacteriology.

Overexpression, purification and characterization of two pyrimidine kinases involved in the biosynthesis of thiamin: 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase

M. Winkler, C. Kinsland, T. Begley, 1998 .

Genome Sequence of Avery's Virulent Serotype 2 Strain D39 of Streptococcus pneumoniae and Comparison with That of Unencapsulated Laboratory Strain R6

J. Glass, H. Tettelin, T. Davidsen, 2006, Journal of bacteriology.

Roles of RodZ and class A PBP1b in the assembly and regulation of the peripheral peptidoglycan elongasome in ovoid‐shaped cells of Streptococcus pneumoniae D39

M. Winkler, O. Massidda, H. C. Tsui, 2022, bioRxiv.

SifR is an Rrf2-family quinone sensor associated with catechol iron uptake in Streptococcus pneumoniae D39

D. Giedroc, M. Winkler, Katherine A. Edmonds, 2022, The Journal of biological chemistry.

Competence beyond Genes: Filling in the Details of the Pneumococcal Competence Transcriptome by a Systems Approach

M. Winkler, D. Morrison, 2019, Journal of bacteriology.

Redefining the sRNA Transcriptome in Streptococcus pneumoniae 1 Serotype 2 Strain D39

D. Rusch, M. Winkler, Kurt Zimmer, 2019 .

Absence of the KhpA and KhpB (JAG/EloR) RNA‐binding proteins suppresses the requirement for PBP2b by overproduction of FtsA in Streptococcus pneumoniae D39

M. Winkler, O. Massidda, H. C. Tsui, 2017, Molecular microbiology.

Suppression and synthetic‐lethal genetic relationships of ΔgpsB mutations indicate that GpsB mediates protein phosphorylation and penicillin‐binding protein interactions in Streptococcus pneumoniae D39

M. Winkler, D. Fadda, P. Branny, 2017, Molecular microbiology.

Roles of the Essential Protein FtsA in Cell Growth and Division in Streptococcus pneumoniae

M. Winkler, D. Fadda, P. Branny, 2016, Journal of bacteriology.

Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumoniae D39

S. Shaw, M. Winkler, E. Kuru, 2014, Molecular microbiology.

Dynamic Distribution of the SecA and SecY Translocase Subunits and Septal Localization of the HtrA Surface Chaperone/Protease during Streptococcus pneumoniae D39 Cell Division

M. Winkler, Kyle J. Wayne, Lok-To Sham, 2011, mBio.

The Pneumococcal Divisome: Dynamic Control of Streptococcus pneumoniae Cell Division

M. Winkler, D. Roper, K. E. Bruce, 2021, Frontiers in Microbiology.

Defective cell wall synthesis in Streptococcus pneumoniae R6 depleted for the essential PcsB putative murein hydrolase or the VicR (YycF) response regulator

K. Kazmierczak, M. Winkler, Wai-Leung Ng, 2004, Molecular microbiology.

The Putative Hydrolase YycJ (WalJ) Affects the Coordination of Cell Division with DNA Replication in Bacillus subtilis and May Play a Conserved Role in Cell Wall Metabolism

S. Biller, W. Burkholder, M. Winkler, 2010, Journal of bacteriology.

Overexpression, Purification and Characterization of Two Pyrimidine Kinases Involved in the Biosynthesis of Thiamin: 4-Amino-5-hydroxymethyl-2-methylpyrimidine Kinase and 4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase.

M. Winkler, C. Kinsland, T. Begley, 2010 .

Structural features of the hisT operon of Escherichia coli K-12.

C. C. Marvel, M. Winkler, E. Penhoet, 1985, Nucleic acids research.

Organization of Peptidoglycan Synthesis in Nodes and Separate Rings at Different Stages of Cell Division of Streptococcus pneumoniae

Erin E. Carlson, S. Shaw, M. Winkler, 2020, bioRxiv.

Movement Dynamics of Divisome and Penicillin-Binding Proteins (PBPs) in Cells of Streptococcus pneumoniae

C. Dekker, S. Shaw, S. Holden, 2018, bioRxiv.

High throughput screening of library compounds against an oligonucleotide substructure of an RNA target

R. Higgs, M. Shapiro, M. Winkler, 2004, Journal of the American Society for Mass Spectrometry.

Single-step purifications of His6-MutH, His6-MutL and His6-MutS repair proteins of escherichia coli K-12.

M. Winkler, G. Feng, 1995, BioTechniques.

Physiological Roles of the Dual Phosphate Transporter Systems in Low and High Phosphate Conditions and in Capsule Maintenance of Streptococcus pneumoniae D39

M. Winkler, Kyle J. Wayne, Dhriti Sinha, 2016, Front. Cell. Infect. Microbiol..

New Class of Competitive Inhibitor of Bacterial Histidine Kinases

M. Winkler, D. Yan, Wai-Leung Ng, 2005, Journal of bacteriology.

A new structural paradigm in copper resistance in Streptococcus pneumoniae

Khadine A. Higgins, D. Giedroc, K. Kazmierczak, 2012, Nature chemical biology.

2-hydroxyglutaric aciduria. possible implications for human dehydrogenase of Escherichia coli K-12 and its of the serA-encoded 3-phosphoglycerate A novel alpha-ketoglutarate reductase activity

M. Winkler, G. Zhao, 2013 .

A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria

M. Winkler, Genshi Zhao, G. Zhao, 1996, Journal of bacteriology.

Ribosomal ribonucleic acid isolated from Salmonella typhimurium: absence of the intact 23S species

M. Winkler, 1979, Journal of bacteriology.

The zinc efflux activator SczA protects Streptococcus pneumoniae serotype 2 D39 from intracellular zinc toxicity

D. Giedroc, M. Winkler, G. Campanello, 2017, Molecular microbiology.

The metalloregulatory zinc site in Streptococcus pneumoniae AdcR, a zinc-activated MarR family repressor.

D. Giedroc, K. Kazmierczak, M. Winkler, 2010, Journal of molecular biology.

Biochemical characterization of gapB-encoded erythrose 4-phosphate dehydrogenase of Escherichia coli K-12 and its possible role in pyridoxal 5'-phosphate biosynthesis

M. Winkler, G. Zhao, A. Pease, 1995, Journal of bacteriology.

Transcription termination at the tryptophan operon attenuator is decreased in vitro by an oligomer complementary to a segment of the leader transcript.

C. Yanofsky, J. Barnett, M. Winkler, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Identification of the miaB Gene, Involved in Methylthiolation of Isopentenylated A37 Derivatives in the tRNA of Salmonella typhimurium andEscherichia coli

M. Winkler, G. Björk, H. C. Tsui, 1999, Journal of bacteriology.

typhimurium andEscherichia coli Derivatives in the tRNA of Salmonella Methylthiolation of Isopentenylated A37 Identification of the miaB Gene, Involved in

M. Winkler, G. Björk, B. Esberg, 2013 .

An unusual genetic link between vitamin B6 biosynthesis and tRNA pseudouridine modification in Escherichia coli K-12

M. Winkler, P. J. Arps, 1987, Journal of bacteriology.

Mutation spoT of Escherichia coli increases expression of the histidine operon deleted for the attenuator

M. Winkler, P. Hartman, R. V. Zawodny, 1979, Journal of bacteriology.

Brucella stationary-phase gene expression and virulence.

M. Winkler, R. Roop, Jason M Gee, 2003, Annual review of microbiology.

Perturbation of manganese metabolism disrupts cell division in Streptococcus pneumoniae

D. Giedroc, M. Winkler, John P. Lisher, 2017, Molecular microbiology.

Suppression of insertions in the complex pdxJ operon of Escherichia coli K-12 by lon and other mutations

Winkler, M. Winkler, H. Lam, 1992, Journal of bacteriology.

Kinetic limitation and cellular amount of pyridoxine (pyridoxamine) 5'-phosphate oxidase of Escherichia coli K-12

M. Winkler, Genshi Zhao, G. Zhao, 1995, Journal of bacteriology.

Structure of the Caulobacter crescentus trpFBA operon

C. M. Ross, M. Winkler, M. E. Winkler, 1988, Journal of bacteriology.

Polymorphism and regulation of the spxB (pyruvate oxidase) virulence factor gene by a CBS‐HotDog domain protein (SpxR) in serotype 2 Streptococcus pneumoniae

J. Morris, K. Kazmierczak, M. Winkler, 2007, Molecular microbiology.

Divergent transcription of pdxB and homology between the pdxB and serA gene products in Escherichia coli K-12

M. Winkler, B. Roa, P. Schoenlein, 1989, Journal of bacteriology.

Identification and Function of the pdxY Gene, Which Encodes a Novel Pyridoxal Kinase Involved in the Salvage Pathway of Pyridoxal 5′-Phosphate Biosynthesis in Escherichia coli K-12

M. Winkler, T. Man, H. C. Tsui, 1998, Journal of bacteriology.

Identification of the pdxK gene that encodes pyridoxine (vitamin B6) kinase in Escherichia coli K-12.

M. Winkler, G. Zhao, Y. Yang, 1996, FEMS microbiology letters.

Maximization of transcription of the serC (pdxF)-aroA multifunctional operon by antagonistic effects of the cyclic AMP (cAMP) receptor protein-cAMP complex and Lrp global regulators of Escherichia coli K-12

M. Winkler, T. Man, A. Pease, 1997, Journal of bacteriology.

1 ! 1 ! A new quorum sensing system ( TprA / PhrA ) for Streptococcus pneumoniae D 39 that 2 ! regulates a lantibiotic biosynthesis gene cluster 3 ! 4 ! 5 !

M. Winkler, R. DiMarchi, B. Lazazzera, 2015 .

Reduction of GC → TA Transversion Mutation by Overexpression of MutS in Escherichia coli K-12

M. Winkler, Jingyong Zhao, 2000, Journal of bacteriology.

Reduction of GC 3 TA Transversion Mutation by Overexpression of MutS in Escherichia coli K-12

M. Winkler, Jingyong Zhao, 2000 .

Negative regulation of mutS and mutH repair gene expression by the Hfq and RpoS global regulators of Escherichia coli K-12

M. Winkler, H. C. Tsui, M E Winkler, 1997, Journal of bacteriology.

Mismatch repair protein MutL becomes limiting during stationary-phase mutation.

R. S. Harris, M. Winkler, S. Rosenberg, 1997, Genes & development.

Altered 3'-terminal RNA structure in phage Qbeta adapted to host factor-less Escherichia coli.

M. Winkler, H. C. Tsui, J. Sogo, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Constitutive expression of PcsB suppresses the requirement for the essential VicR (YycF) response regulator in Streptococcus pneumoniae R6 §

K. Kazmierczak, M. Winkler, G. Robertson, 2003, Molecular microbiology.

Promoter- and attenuator-related metabolic regulation of the Salmonella typhimurium histidine operon

D. J. Roth, M. Winkler, P. Hartman, 1978, Journal of bacteriology.

Regulation of the pspA Virulence Factor and Essential pcsB Murein Biosynthetic Genes by the Phosphorylated VicR (YycF) Response Regulator in Streptococcus pneumoniae

M. Winkler, Wai-Leung Ng, H. C. Tsui, 2005, Journal of bacteriology.

Regulation of Substrate Recognition by the MiaA tRNA Prenyltransferase Modification Enzyme of Escherichia coliK-12*

M. Winkler, Yuqing Chen, Ho Leung, 1997, The Journal of Biological Chemistry.

The mutL repair gene of Escherichia coli K‐12 forms a superoperon with a gene encoding a new cell‐wall amidase

M. Winkler, H. C. Tsui, Genshi Zhao, 1994, Molecular microbiology.

Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross‐talk in Streptococcus pneumoniae D39 cells

K. Kazmierczak, M. Winkler, Kyle J. Wayne, 2012, Molecular Microbiology.

DegU‐phosphate activates expression of the anti‐sigma factor FlgM in Bacillus subtilis

M. Winkler, Alina D. Gutu, Lok-To Sham, 2011, Molecular microbiology.

Mismatch repair is diminished during stationary-phase mutation.

R. S. Harris, M. Winkler, S. Rosenberg, 1999, Mutation research.

Characterization of Mutants Deficient in the l,d-Carboxypeptidase (DacB) and WalRK (VicRK) Regulon, Involved in Peptidoglycan Maturation of Streptococcus pneumoniae Serotype 2 Strain D39

M. Winkler, Lok-To Sham, Skye M. Barendt, 2011, Journal of bacteriology.

Overlap between pdxA and ksgA in the complex pdxA-ksgA-apaG-apaH operon of Escherichia coli K-12

M. Winkler, B. Roa, D. M. Connolly, 1989, Journal of bacteriology.

Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12

M. Winkler, D. M. Connolly, 1989, Journal of bacteriology.

Genetics and Regulation of Base Modification in the tRNA and rRNA of Prokaryotes and Eukaryotes

M. Winkler, 1998 .

Transcription of the mutL repair, miaA tRNA modification, hfq pleiotropic regulator, and hflA region protease genes of Escherichia coli K-12 from clustered Esigma32-specific promoters during heat shock

M. Winkler, H. C. Tsui, G. Feng, 1996, Journal of bacteriology.

Structure of Escherichia coli K-12 miaA and characterization of the mutator phenotype caused by miaA insertion mutations

M. Winkler, D. M. Connolly, M. E. Winkler, 1991, Journal of bacteriology.

Pausing of RNA polymerase during in vitro transcription of the tryptophan operon leader region.

C. Yanofsky, M. Winkler, 1981, Biochemistry.

Analysis of the requirements for transcription pausing in the tryptophan operon.

C. Yanofsky, R. Kolter, M. Winkler, 1985, Journal of molecular biology.

Solution conformations of unmodified and A(37)N(6)-dimethylallyl modified anticodon stem-loops of Escherichia coli tRNA(Phe).

M. Winkler, E. Nikonowicz, J. Cabello-Villegas, 2002, Journal of Molecular Biology.

Folding of eukaryotic proteins produced in Escherichia coli.

M. Winkler, R. Kelley, Robert F. Kelley, 1990, Genetic engineering.

Recent advances in pneumococcal peptidoglycan biosynthesis suggest new vaccine and antimicrobial targets.

M. Winkler, Lok-To Sham, H. C. Tsui, 2012, Current opinion in microbiology.

Cellular Mn/Zn Ratio Influences Phosphoglucomutase Activity and Capsule Production in Streptococcus pneumoniae D39

M. Winkler, Julia E. Martin, N. Bhattarai, 2021, Journal of bacteriology.

Essential PcsB putative peptidoglycan hydrolase interacts with the essential FtsXSpn cell division protein in Streptococcus pneumoniae D39

M. Winkler, Lok-To Sham, Skye M. Barendt, 2011, Proceedings of the National Academy of Sciences.

Pivotal Roles for Ribonucleases in Streptococcus pneumoniae Pathogenesis

M. Winkler, Dhriti Sinha, J. Frick, 2021, bioRxiv.

S1 Domain RNA-Binding Protein CvfD Is a New Posttranscriptional Regulator That Mediates Cold Sensitivity, Phosphate Transport, and Virulence in Streptococcus pneumoniae D39

J. Richardson, M. Winkler, H. C. Tsui, 2020, Journal of Bacteriology.

Redefining the Small Regulatory RNA Transcriptome in Streptococcus pneumoniae Serotype 2 Strain D39

D. Rusch, M. Winkler, Kurt Zimmer, 2019, Journal of bacteriology.

Suppression of a deletion mutation in the gene encoding essential PBP2b reveals a new lytic transglycosylase involved in peripheral peptidoglycan synthesis in Streptococcus pneumoniae D39

M. Winkler, T. Bernhardt, H. C. Tsui, 2016, Molecular microbiology.

Positive Growth Rate-Dependent Regulation of the pdxA, ksgA, and pdxB Genes of Escherichia coli K-12

M. Winkler, W. Luo, A. Pease, 2002, Journal of bacteriology.

A Mn-sensing riboswitch activates expression of a Mn2+/Ca2+ ATPase transporter in Streptococcus

D. Giedroc, M. Winkler, Julia E. Martin, 2019, Nucleic acids research.

Escherichia colit

M. Winkler, Departent, 2022 .

The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes

M. Winkler, R. Lewis, R. Daniel, 2018, bioRxiv.

Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division.

Erin E. Carlson, M. Winkler, Lok-To Sham, 2012, ACS chemical biology.

Isolation of a pdxJ point mutation that bypasses the requirement for the PdxH oxidase in pyridoxal 5' -phosphate coenzyme biosynthesis in Escherichia coli K-12

M. Winkler, T. Man, G. Zhao, 1996, Journal of bacteriology.

Characterization of the complex pdxH-tyrS operon of Escherichia coli K-12 and pleiotropic phenotypes caused by pdxH insertion mutations

M. Winkler, H. Lam, 1992, Journal of bacteriology.

Expression, purification, and characterization of recombinant Escherichia coli pyridoxine 5'-phosphate oxidase.

M. Winkler, M. D. di Salvo, G. Zhao, 1998, Protein expression and purification.

Essentiality, Bypass, and Targeting of the YycFG (VicRK) Two-Component Regulatory System in Gram-Positive Bacteria

J. Hoch, M. Winkler, 2008, Journal of bacteriology.

Identification and Characterization of Noncoding Small RNAs in Streptococcus pneumoniae Serotype 2 Strain D39

Andrew L. Feig, M. Winkler, A. Feig, 2009, Journal of bacteriology.

The flk gene of Salmonella typhimurium couples flagellar P- and L-ring assembly to flagellar morphogenesis

M. Winkler, K. Hughes, J. Karlinsey, 1997, Journal of bacteriology.

Extensive homology between the Escherichia coli K-12 SerC(PdxF) aminotransferase and a protein encoded by a progesterone-induced mRNA in rabbit and human endometria.

M. Winkler, H. Lam, A. van der Zel, 1989, Nucleic acids research.

Movement dynamics of divisome proteins and PBP2x:FtsW in cells of Streptococcus pneumoniae

C. Dekker, S. Shaw, S. Holden, 2019, Proceedings of the National Academy of Sciences.

Identification and Characterization of Noncoding Small RNAs in Streptococcus pneumoniae Serotype 2 Strain D 39 †

M. Winkler, A. Feig, Lok-To Sham, 2009 .

Localization and Cellular Amounts of the WalRKJ (VicRKX) Two-Component Regulatory System Proteins in Serotype 2 Streptococcus pneumoniae

M. Winkler, Alina D. Gutu, Kyle J. Wayne, 2010, Journal of bacteriology.

Kinetic and mechanistic analyses of new classes of inhibitors of two-component signal transduction systems using a coupled assay containing HpkA-DrrA from Thermotoga maritima.

M. Winkler, M. Bures, R. Gilmour, 2004, Microbiology.

Role of HdeA in acid resistance and virulence in Brucella abortus 2308.

M. Winkler, R. Roop, B. Bellaire, 2005, Veterinary microbiology.

Singular structures and operon organizations of essential two-component systems in species of Streptococcus.

M. Winkler, Wai‐Leung Ng, 2004, Microbiology.

Molecular analysis of mutS expression and mutation in natural isolates of pathogenic Escherichia coli.

T. Cebula, J. E. Leclerc, M. Winkler, 2003, Microbiology.

The miaA Mutator Phenotype ofEscherichia coli K-12 Requires Recombination Functions

M. Winkler, Jingyong Zhao, Ho Leung, 2001, Journal of bacteriology.

hisT is part of a multigene operon in Escherichia coli K-12

C. C. Marvel, M. Winkler, E. Penhoet, 1985, Journal of bacteriology.

Instability of ackA (Acetate Kinase) Mutations and Their Effects on Acetyl Phosphate and ATP Amounts in Streptococcus pneumoniae D39

Kristy L. Hentchel, K. Kazmierczak, M. Winkler, 2010, Journal of bacteriology.

Global Transcriptional Analysis of clpP Mutations of Type 2 Streptococcus pneumoniae and Their Effects on Physiology and Virulence

M. Winkler, G. Robertson, R. Gilmour, 2002, Journal of bacteriology.

Involvement of the gapA- and epd(gapB)-Encoded Dehydrogenases in Pyridoxal 5′-Phosphate Coenzyme Biosynthesis in Escherichia coli K-12

M. Winkler, T. Man, Genshi Zhao, 1998, Journal of bacteriology.

Genetic and Genomic Approaches for Delineating the Pathway of Pyridoxal 5’-Phosphate Coenzyme Biosynthesis in Escherichia coli

M. Winkler, 2000 .

4-Phospho-hydroxy-L-threonine is an obligatory intermediate in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12.

M. Winkler, G. Zhao, 1996, FEMS microbiology letters.

Biochemical characterization of essential cell division proteins FtsX and FtsE that mediate peptidoglycan hydrolysis by PcsB in Streptococcus pneumoniae

M. Winkler, A. Davidson, C. Stauffacher, 2016, MicrobiologyOpen.

Negative regulation of MurZ and MurA underlies the essentiality of GpsB‐ and StkP‐mediated protein phosphorylation in Streptococcus pneumoniae D39

M. Winkler, P. Branny, O. Massidda, 2023, Molecular microbiology.

1H, 13C, 15N resonance assignments of the extracellular loop 1 domain (ECL1) of Streptococcus pneumoniae D39 FtsX, an essential cell division protein

D. Giedroc, M. Winkler, Yue Fu, 2016, Biomolecular NMR assignments.

The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes

M. Winkler, R. Lewis, R. Daniel, 2019, Nature Communications.

Mutation spoTofEscherichia coli Increases Expression ofthe Histidine OperonDeleted fortheAttenuatort

M. Winkler, R. V. Zawodny, 1979 .

Divergent Transcription ofpdxBandHomology between thepdxB andserAGeneProducts inEscherichia coli K-12

M. Winkler, B. Roa, 1989 .

Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumoniae D39

S. Shaw, M. Winkler, M. VanNieuwenhze, 2014, Molecular microbiology.

Strongly reduced phage Qbeta replication, but normal phage MS2 replication in an Escherichia coli K12 mutant with inactivated Qbeta host factor (hfq) gene.

M. Winkler, H. Weber, Q. Su, 1997, Virology.

Characterization of Mutants Deficient in the l,d-Carboxypeptidase (DacB) and WalRK (VicRK) Regulon, Involved in Peptidoglycan Maturation of Streptococcus pneumoniae Serotype 2 Strain D39

M. Winkler, Lok-To Sham, Skye M. Barendt, 2011, Journal of bacteriology.

The Requirement for Pneumococcal MreC and MreD Is Relieved by Inactivation of the Gene Encoding PBP1a

M. Winkler, Adrian D. Land, 2011, Journal of bacteriology.

Biochemical reconstitution defines new functions for membrane-bound glycosidases in assembly of the bacterial cell wall

M. Winkler, S. Walker, A. Taguchi, 2021, Proceedings of the National Academy of Sciences.

Biosynthesis of Small Molecules

M. Winkler, 2001 .

Vancomycin Tolerance Induced by Erythromycin but Not by Loss of vncRS, vex3, or pep27 Function in Streptococcus pneumoniae

W. H. Coleman, M. Winkler, L. Grinius, 2002, Journal of bacteriology.

Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross‐talk in Streptococcus pneumoniae D39 cells

K. Kazmierczak, M. Winkler, Kyle J. Wayne, 2012, Molecular microbiology.

Recent advances in pneumococcal peptidoglycan biosynthesis suggest new vaccine and antimicrobial targets.

M. Winkler, Lok-To Sham, Adrian D. Land, 2012, Current opinion in microbiology.

Novel Electrophilic Scaffold for Imaging of Essential Penicillin-Binding Proteins in Streptococcus pneumoniae.

Erin E. Carlson, M. Winkler, Ozden Kocaoglu, 2017, ACS chemical biology.

1H, 13C, 15N resonance assignments of the extracellular loop 1 domain (ECL1) of Streptococcus pneumoniae D39 FtsX, an essential cell division protein

D. Giedroc, M. Winkler, K. E. Bruce, 2015, Biomolecular NMR Assignments.

Flk Couples flgM Translation to Flagellar Ring Assembly in Salmonella typhimurium

M. Winkler, K. Hughes, J. Karlinsey, 1998, Journal of bacteriology.

Biosynthesis of Histidine

M. Winkler, Smirla Ramos-Montañez, 2009, EcoSal Plus.