D. Hilbert

发表

BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.

Amy S Orr, P. Moore, O. Belvedere, 1999, Science.

Baculovirus Stimulates Antiviral Effects in Mammalian Cells

R. Schreiber, D. Hilbert, A. Gronowski, 1999, Journal of Virology.

Chapter 9 – Ontogeny of the HA-Responsive B-Cell Repertoire: Interaction of Heritable and Inducible Mechanisms in the Establishment of Phenotype

D. Hilbert, M. Cancro, S. Raychaudhuri, 1984 .

Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.

S. Korsmeyer, P. Hammerman, J. Opferman, 2008, Blood.

Multispecific antibodies: format follows function

V. Roschke, D. Hilbert, D. LaFleur, 2015 .

Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis

V. Roschke, D. Hilbert, Geping Wang, 2012, mAbs.

Monoclonal antibody therapeutics with up to five specificities

Andrew Burnette, V. Roschke, D. Hilbert, 2013, mAbs.

Increased Blood Volume and CD34+CD38− Progenitor Cell Recovery Using a Novel Umbilical Cord Blood Collection System

R. Spizzo, O. Belvedere, D. Hilbert, 2000, Stem cells.

In vitro cultured stromal cells from human tonsils display a distinct phenotype and induce B cell adhesion and proliferation

O. Belvedere, D. Hilbert, G. Lisignoli, 1996, European journal of immunology.

Mechanism of apoptosis suppression by phorbol ester in IL-6-starved murine plasmacytomas: role of PKC modulation and cell cycle.

D. Hilbert, R. Nordan, L. Romanova, 1996, Biochemistry.

T cell derived IL-6 is differentially required for antigen-specific antibody secretion by primary and secondary B cells.

S. Rudikoff, D. Hilbert, R. Nordan, 1989, Journal of immunology.

In vitro culture of a primary plasmacytoma that has retained its dependence on pristane conditioned microenvironment for growth.

D. Hilbert, M. Potter, H. Coon, 1990, Current topics in microbiology and immunology.

Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.

J M Ward, J. Ward, S. Rudikoff, 1996, Toxicology and applied pharmacology.

Synthesis and release of B-lymphocyte stimulator from myeloid cells.

P. Moore, O. Belvedere, P. Feng, 2001, Blood.

Chimeric Antigen Receptors Incorporating D Domains Targeting CD123 Direct Potent Mono- and Bi-specific Antitumor Activity of T Cells.

D. Hilbert, T. Fry, J. Edwards, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus

V. Roschke, D. Hilbert, K. Baker, 2004, Annals of the rheumatic diseases.

Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases.

V. Roschke, D. Hilbert, W. Stohl, 2001, Arthritis and rheumatism.

Phenotypic characterization of immunomagnetically purified umbilical cord blood CD34+ cells.

M. Baccarani, O. Belvedere, D. Hilbert, 1999, Blood Cells, Molecules & Diseases.

Interleukin 6 is essential for in vivo development of B lineage neoplasms

S. Rudikoff, D. Hilbert, B. Mock, 1995, The Journal of experimental medicine.

Distinct tumorigenic potential of abl and raf in B cell neoplasia: abl activates the IL-6 signaling pathway.

W. Leonard, S. Rudikoff, D. Hilbert, 1996, Immunity.

Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator.

V. Roschke, D. Hilbert, R. Minter, 2003, Arthritis and rheumatism.

Cutting Edge: BLyS Enables Survival of Transitional and Mature B Cells Through Distinct Mediators1

D. Hilbert, M. Cancro, R. Lindsley, 2002, The Journal of Immunology.

Attenuation of Apoptosis Underlies B Lymphocyte Stimulator Enhancement of Humoral Immune Response

M. Tourigny, Hayyoung Lee, S. Chen‐Kiang, 2000, The Journal of experimental medicine.

T cells induce terminal differentiation of transformed B cells to mature plasma cell tumors.

S. Rudikoff, D. Hilbert, U. Rapp, 1995, Proceedings of the National Academy of Sciences of the United States of America.

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

B. Nardelli, D. Hilbert, P. Casali, 2002, Nature Immunology.

Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse.

D. Hilbert, W. Stohl, M. Leandro, 2006, Arthritis and rheumatism.

The discovery and development of belimumab: the anti-BLyS–lupus connection

D. Hilbert, W. Stohl, 2012, Nature Biotechnology.

B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels

D. Hilbert, D. Nemazee, W. Stohl, 2005, Arthritis research & therapy.

B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations.

V. Roschke, D. Hilbert, K. Baker, 2003, Arthritis and rheumatism.

Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis.

V. Roschke, D. Hilbert, W. Stohl, 2003, Arthritis and rheumatism.

BLyS and APRIL Form Biologically Active Heterotrimers That Are Expressed in Patients with Systemic Immune-Based Rheumatic Diseases1

V. Roschke, B. Nardelli, S. Sosnovtseva, 2002, The Journal of Immunology.

B lymphocyte stimulator protein-associated increase in circulating autoantibody levels may require CD4+ T cells: lessons from HIV-infected patients.

V. Roschke, S. Sosnovtseva, D. Hilbert, 2002, Clinical immunology.

B Lymphocyte Stimulator (BLyS): A Therapeutic Trichotomy for the Treatment of B Lymphocyte Diseases

P. Moore, B. Nardelli, D. Hilbert, 2002, Leukemia & lymphoma.

Distinct Mediators Transitional and Mature B Cells Through Cutting Edge: BLyS Enables Survival of

D. Hilbert, M. Cancro, R. Lindsley, 2002 .

Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers

D. Hilbert, M. Cancro, K. Clise-Dwyer, 2001, Current Biology.

Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis

H. Ditzel, D. Hilbert, W. Stohl, 2004, Annals of the rheumatic diseases.

Susceptibility and resistance to Moloney murine leukemia virus-induced promonocytic leukemia.

D. Hilbert, L. Wolff, V. Nazarov, 1994, Virology.

A Comparative Analyis of the Anti-Phosphorylcholine Response of CLA and BALB/c Mice

D. Hilbert, M. Cancro, 1986 .

Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain

D. Hilbert, J. Edwards, L. Richman, 2022, Molecular cancer therapeutics.

In vitro culture of primary plasmacytomas requires stromal cell feeder layers.

S. Rudikoff, D. Hilbert, M. Potter, 1993, Proceedings of the National Academy of Sciences of the United States of America.

BLyS and BLyS receptor expression in non-Hodgkin's lymphoma.

J. Briones, D. Hilbert, J. Timmerman, 2002, Experimental hematology.

patients with inflammatory arthritis isomerase IgG in serum and synovial fluid from Raised levels of anti-glucose-6-phosphate

H. Ditzel, D. Hilbert, V. Benoit, 2005 .

Discovery of high‐affinity peptide binders to BLyS by phage display

V. Roschke, D. Hilbert, J. Beltzer, 2005, Journal of molecular recognition : JMR.

Extended Report : Elevated levels of anti-glucose-6-phosphate isomerase ( GPI ) IgG in serum and synovial fluid from patients with inflammatory arthritis

H. Ditzel, D. Hilbert, W. Stohl, 2004 .

B lymphocytes from individuals with common variable immunodeficiency respond to B lymphocyte stimulator (BLyS protein) in vitro.

D. Hilbert, D. Nelson, D. Stewart, 2003, Clinical immunology.

Susceptibility and resistance to J3V1 retrovirus-induced murine plasmacytomagenesis in reconstituted severe combined immunodeficient mice.

S. Rudikoff, J. Pumphrey, D. Hilbert, 1993, Oncogene.

Transfer of HIV-1 to human tonsillar stromal cells following cocultivation with infected lymphocytes.

D. Hilbert, N. Zini, G. Lisignoli, 1994, AIDS research and human retroviruses.

BLyS BINDS TO B CELLS WITH HIGH AFFINITY AND INDUCES ACTIVATION OF THE TRANSCRIPTION FACTORS NF-kappaB AND ELF-1.

J. Giri, B. Nardelli, H. Olsen, 2001, Cytokine.

Serological changes following B cell depletion therapy in Systemic Lupus Erythematosus: Relationship with BLyS

Ehrenstein, D. Isenberg, D. Hilbert, 2004 .

Long‐term thymic reconstitution by peripheral CD4 and CD8 single‐positive lymphocytes

S. Rudikoff, D. Hilbert, K. Holmes, 1993, European journal of immunology.

Developmental aspects of B-cell repertoire phenotype

D. Hilbert, M. Cancro, Michael P. Cancro, 1983, Survey of immunologic research.

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

T. Pineau, S. Rudikoff, D. Hilbert, 1995, Science.

MOLECULAR CANCER THERAPEUTICS | LARGE MOLECULE THERAPEUTICS Preclinical Ef ﬁ cacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain

D. Hilbert, J. Edwards, L. Richman, 2022 .

Disseminated growth of murine plasmacytoma: similarities to multiple myeloma.

S. Rudikoff, J. Pumphrey, V. Roschke, 1998, Cancer research.