C. Deber

发表

The Assembly Motif of a Bacterial Small Multidrug Resistance Protein*

Bradley E. Poulsen, A. Rath, C. Deber, 2009, Journal of Biological Chemistry.

Accessibility and dynamics of Cys residues in Bacteriophage IKe and M13 major coat protein mutants.

C. Deber, J. Boggs, A. R. Khan, 1995, Biochemistry.

Packing of coat protein amphipathic and transmembrane helices in filamentous bacteriophage M13: role of small residues in protein oligomerization.

H. Li, C. Deber, D. Marvin, 1995, Journal of molecular biology.

Biophysical characterization of wild-type and mutant bacteriophage IKe major coat protein in the virion and in detergent micelles.

C. Deber, K. Williams, 1996, Biochemistry.

Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

A. Rath, C. Deber, M. Glibowicka, 2009, Proceedings of the National Academy of Sciences.

Sequence context strongly modulates association of polar residues in transmembrane helices.

D. Engelman, C. Deber, R. Melnyk, 2003, Journal of molecular biology.

Non-random distribution of amino acids in the transmembrane segments of human type I single span membrane proteins.

C. Deber, R. Reithmeier, K. Williams, 1993, Journal of molecular biology.

Differential binding of L- vs. D-isomers of cationic antimicrobial peptides to the biofilm exopolysaccharide alginate.

C. Deber, Soyoung Lee, J. Mak, 2013, Protein and peptide letters.

Cationic Hydrophobic Peptides with Antimicrobial Activity

C. Deber, Li-ping Liu, M. Stark, 2002, Antimicrobial Agents and Chemotherapy.

Basis for Selectivity of Cationic Antimicrobial Peptides for Bacterial Versus Mammalian Membranes*

C. Deber, L. Burrows, E. Glukhov, 2005, Journal of Biological Chemistry.

Transmembrane segment peptides with double D‐amino acid replacements: Helicity, hydrophobicity, and antimicrobial activity

C. Deber, R. Melnyk, Li-ping Liu, 2003, Biopolymers.

Uncoupling Hydrophobicity and Helicity in Transmembrane Segments

C. Deber, Li-ping Liu, Charles M. Deber, 1998, The Journal of Biological Chemistry.

Amino acid composition of the membrane and aqueous domains of integral membrane proteins.

R. Deber, C. Deber, C. Brandl, 1986, Archives of biochemistry and biophysics.

Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB

Philip M. Kim, C. Deber, Michael Garton, 2018, Proceedings of the National Academy of Sciences.

Erratum: A measure of helical propensity for amino acids in membrane environments

C. Deber, Shun-Cheng Li, Shun-Cheng Li, 1994, Nature Structural Biology.

Peptide environment specifies conformation. Helicity of hydrophobic segments compared in aqueous, organic, and membrane environments.

C. Deber, S. C. Li, 1993, The Journal of biological chemistry.

Design of transmembrane peptides: coping with sticky situations.

A. Rath, C. Deber, 2013, Methods in molecular biology.

Membrane interactions of designed cationic antimicrobial peptides: the two thresholds.

C. Deber, L. Burrows, E. Glukhov, 2008, Biopolymers.

Cyclic peptides. 3. Solution conformations of cyclo(serylprolylglycylserylprolylglycyl) from nuclear magnetic resonance.

E. Blout, D. Torchia, C. Deber, 1972, Journal of the American Chemical Society.

Cyclic peptides. II. Solution conformations of cyclo(ProlyLserylglycylprolylserylglycyl) from nuclear magnetic resonance.

E. Blout, D. Torchia, C. Deber, 1972, Journal of the American Chemical Society.

D-glucose binding increases secondary structure of human erythrocyte monosaccharide transport protein.

C. Deber, A. Pawagi, 1987, Biochemical and biophysical research communications.

Roles of Hydrophobicity and Charge Distribution of Cationic Antimicrobial Peptides in Peptide-Membrane Interactions*

Christopher M Yip, C. Deber, C. Yip, 2012, The Journal of Biological Chemistry.

Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides.

S. Sharpe, C. Deber, Huong Q Nguyen, 2017, Bioorganic & medicinal chemistry.

Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms

C. Deber, Y. Yau, V. Waters, 2018, Scientific Reports.

Anionic phospholipids modulate peptide insertion into membranes.

C. Deber, L. P. Liu, 1997, Biochemistry.

Activity of novel non-amphipathic cationic antimicrobial peptides against Candida species.

C. Deber, L. Burrows, E. Glukhov, 2006, The Journal of antimicrobial chemotherapy.

Thioester-isocyanides: versatile reagents for the synthesis of cycle-tail peptides.

C. Deber, A. Yudin, Lois M. Yin, 2012, Chemical communications.

Influence of ether linkage on the lamellar to hexagonal phase transition of ethanolamine phospholipids.

C. Deber, D. Hughes, J. Boggs, 1981, Biochemistry.

The hydrophobicity threshold for peptide insertion into membranes

C. Deber, R. Reithmeier, Li-ping Liu, 2002 .

Structural effects of extracellular loop mutations in CFTR helical hairpins.

C. Deber, C. Bear, M. Glibowicka, 2018, Biochimica et biophysica acta. Biomembranes.

Evidence that the translocon may function as a hydropathy partitioning filter.

C. Deber, Cory M. Mulvihill, 2010, Biochimica et biophysica acta.

Cyclic peptides. I. Cyclo(tri-l-prolyl) and derivatives. Synthesis and molecular conformation from nuclear magnetic resonance.

E. Blout, D. Torchia, C. Deber, 1971, Journal of the American Chemical Society.

Congenital Heart Block Maternal Sera Autoantibodies Target an Extracellular Epitope on the α1G T-Type Calcium Channel in Human Fetal Hearts

C. Ackerley, A. Rath, C. Deber, 2013, PloS one.

Membrane-adjacent regions of receptor proteins

R. Deber, C. Deber, C. Brandl, 1988 .

Anti-Infectives Restore ORKAMBI® Rescue of F508del-CFTR Function in Human Bronchial Epithelial Cells Infected with Clinical Strains of P. aeruginosa

C. Deber, C. Bear, T. Stone, 2020, Biomolecules.

Functional rescue of DeltaF508-CFTR by peptides designed to mimic sorting motifs.

C. Deber, D. Rotin, Patrick Kim Chiaw, 2009, Chemistry & biology.

Glycine and β‐branched residues support and modulate peptide helicity in membrane environments

C. Deber, Shun‐Cheng Li, 1992, FEBS letters.

Glu-mediated dimerization of the transmembrane region of the oncogenic neu protein

C. Deber, S. Shoelson, Shun‐Cheng Li, 1994 .

Ile and Val residues are helix-promoters in transmembrane segments

C. Deber, S.-C. Li, 1994 .

Transmembrane region of wild-type and mutant M13 coat proteins. Conformational role of beta-branched residues.

C. Deber, M. Glibowicka, Z. Li, 1992, The Journal of biological chemistry.

Role of membrane lipids in peptide hormone function: binding of enkephalins to micelles.

C. Deber, B. Behnam, 1984, Proceedings of the National Academy of Sciences of the United States of America.

A minimal helical-hairpin motif provides molecular-level insights into misfolding and pharmacological rescue of CFTR

C. Deber, S. Keller, M. Schlierf, 2018, Communications Biology.

Conformational Role of Gly Residues in Transmembrane Segments of Wild Type and Mutant M13 Coat Proteins

C. Deber, M. Glibowicka, Zuomei Li, 1992 .

Non-native interhelical hydrogen bonds in the cystic fibrosis transmembrane conductance regulator domain modulated by polar mutations.

C. Deber, A. Therien, Lia Cardarelli, 2004, Biochemistry.

Spontaneous vesicularization of myelin lipids is counteracted by myelin basic protein.

P. Fraser, C. Deber, R. Rand, 1986, Biochimica et biophysica acta.

The modulation of bovine milk D-galactosyltransferase by various phosphatidylethanolamines.

C. Deber, M. Moscarello, M. Mitranic, 1986, Carbohydrate research.

Surface accessibility of 13C-labeled lysine residues in membrane-bound myelin basic protein.

P. Fraser, C. Deber, 1984, The Journal of biological chemistry.

Cyclic Peptides VII. The Synthesis and Characterization of Cyclic Peptides with Repeating Pro‐Gly Sequences

E. Blout, C. Deber, 1974 .

Cation‐binding cyclic peptides with lipophilic tails

C. Deber, P. Adawadkar, 1979, Biopolymers.

CFTR transmembrane segments are impaired in their conformational adaptability by a pathogenic loop mutation and dynamically stabilized by Lumacaftor

C. Deber, M. Schlierf, G. Krainer, 2019, The Journal of Biological Chemistry.

Transmembrane Segment Mimic Peptides Containing Peptoid Residues

C. Deber, M. Maeda, Yan-chun Tang, 2001 .

Aqueous solubility and membrane interactions of hydrophobic peptides with peptoid tags.

C. Deber, Yan-chun Tang, Yan-chun Tang, 2004, Biopolymers.

Effect of Detergents on Intramolecular Helix-Helix Packing in a Membrane-Based Peptide Derived from CFTR

C. Deber, A. Therien, 2001 .

A Transmembrane Segment Mimic Derived from Escherichia coli Diacylglycerol Kinase Inhibits Protein Activity*

J. Bowie, C. Deber, R. Melnyk, 2003, Journal of Biological Chemistry.

Polar residues in membrane domains of proteins: molecular basis for helix-helix association in a mutant CFTR transmembrane segment.

C. Deber, R. Melnyk, A. Partridge, 2002, Biochemistry.

Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity.

C. Deber, R. Reithmeier, J. Wang, 1994, Journal of molecular biology.

NMR investigation of the charge isomers of bovine myelin basic protein.

C. Deber, M. Moscarello, S. Cheifetz, 1984, Archives of biochemistry and biophysics.

Microheterogeneity of bovine myelin basic protein studied by nuclear magnetic resonance spectroscopy

C. Deber, M. Moscarello, S. Cheifetz, 1983, Biopolymers.

Synthetic cation transport peptides: calcium transport across phospholipid membranes.

C. Deber, M. Young, J. Tom-Kun, 1980, Biochemistry.

Direct observation by carbon-13 nuclear magnetic resonance of membrane-bound human myelin basic protein.

C. Deber, J. Boggs, M. Moscarello, 1980, Biochemistry.

Calcium transport by ionophorous peptides in dog and human lymphocytes detected by quin-2 fluorescence.

C. Deber, L. Hsu, 1986, Biochemical and biophysical research communications.

Synthesis and characterization of halogenated derivatives of the ionophore A23187: enhanced calcium ion transport specificity by the 4-bromo derivative.

C. Deber, R. Molloy, D. Babcock, 1981, Biochemistry.

Synthesis of an ion-binding peptide (DECYL-2) more selective for calcium than ionophore A23187.

C. Deber, P. Adawadkar, J. Tom-Kun, 1978, Biochemical and biophysical research communications.

Membrane partitioning and helix formation studied with designed hydrophobic peptides

C. Deber, Shun‐Cheng Li, 1995 .

The N Terminus of the Qcr7 Protein of the Cytochromebc 1 Complex Is Not Essential for Import into Mitochondria in Saccharomyces cerevisiae but Is Essential for Assembly of the Complex*

B. Trumpower, C. Deber, B. Robinson, 1997, The Journal of Biological Chemistry.

Bromo-A23187: a nonfluorescent calcium ionophore for use with fluorescent probes.

S. Grinstein, C. Deber, E. Mack, 1985, Analytical biochemistry.

Conformational energy of proline-containing peptides in a non-polar environment

C. Deber, A. Polinsky, M. Goodman, 1991 .

Hydrophobic helical hairpins: design and packing interactions in membrane environments.

C. Deber, C. Heslop, Rachel M. Johnson, 2004, Biochemistry.

Gas chromatographic/mass spectrometric analysis of methylphenidate (ritalin) in serum.

C. Deber, J. Thiessen, S. Soldin, 1980, Clinical biochemistry.

Modulation of Substrate Efflux in Bacterial Small Multidrug Resistance Proteins by Mutations at the Dimer Interface

Bradley E. Poulsen, C. Deber, F. Cunningham, 2011, Journal of bacteriology.

Modulation of Substrate Efﬂux in Bacterial Small Multidrug Resistance Proteins by Mutations at the Dimer Interface (cid:1)

Bradley E. Poulsen, C. Deber, Katie K Lee, 2011 .

A lipid vesicle system for probing voltage‐dependent peptide–lipid interactions: Application to alamethicin channel formation

C. Deber, G. Woolley, 1989, Biopolymers.

Potential‐sensitive membrane association of a fluorescent dye

C. Deber, G. Woolley, Moira K. Kapral, 1987 .

CYCLIC PEPTIDES PART 9, CONFORMATIONS OF A SYNTHETIC ION‐BINDING CYCLIC PEPTIDE, CYCLO‐(PRO‐GLY)3, FROM CIRCULAR DICHROISM AND (1)H AND (13)C NUCLEAR MAGNETIC RESONANCE

E. Blout, C. Deber, V. Madison, 1974 .

Cyclic peptides. V. 1 H and 13 C nuclear magnetic resonance determination of the preferred beta conformation for proline-containing cyclic hexapeptides.

E. Blout, C. Deber, L. G. Pease, 1973, Journal of the American Chemical Society.

Peptides, structure and function : proceedings of the eighth American Peptide Symposium

K. Kopple, V. Hruby, C. Deber, 1983 .

Why cyclic peptides? Complementary approaches to conformations

E. Blout, C. Deber, V. Madison, 1976 .

Interhelical Packing in Detergent Micelles

C. Deber, A. Therien, 2002, The Journal of Biological Chemistry.

Therapeutic design of peptide modulators of protein-protein interactions in membranes.

C. Deber, Charles M Deber, Tracy A Stone, 2017, Biochimica et biophysica acta. Biomembranes.

Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environment.

C. Deber, K. Williams, N. Goto, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Side chain interactions in aromatic dipeptides

C. Deber, Henry Joshua, 1972, Biopolymers.

Cyclic peptides. VIII. Carbon-13 and proton nuclear magnetic resonance evidence for slow cis'-trans' rotation in a cyclic tetrapeptide

E. Blout, C. Deber, E. Fossel, 1974 .

Conformations of (X-L-Pro-Y)2 cyclic hexapeptides. Preferred beta-turn conformers and implications for beta turns in proteins.

E. Blout, L. Gierasch, C. Deber, 1981, Biochemistry.

Cyclic peptides. 17. Metal and amino acid complexes of cyclo(pro-gly)4 and analogues studied by nuclear magnetic resonance and circular dichroism.

E. Blout, C. Deber, V. Madison, 1977, Journal of the American Chemical Society.

Cyclic peptides. Amino acid-cyclic peptides complexes

E. Blout, C. Deber, 1974 .

Carbon-13 chemical shifts of amides and imino acid residues. Effects of the carbonyl substituent and syn-anti geometries

J. R. Lyerla, D. Torchia, C. Deber, 1974 .

Conjugation of polyethylene glycol via a disulfide bond confers water solubility upon a peptide model of a protein transmembrane segment.

C. Deber, N. Pomroy, 1999, Analytical biochemistry.

Solubilization of hydrophobic peptides by reversible cysteine PEGylation.

C. Deber, N. Pomroy, Neil C. Pomroy, 1998, Biochemical and biophysical research communications.

Nuclear magnetic resonance evidence for cis-peptide bonds in proline oligomers.

E. Blout, C. Deber, F. Bovey, 1970, Journal of the American Chemical Society.

Peptides in membranes: Lipid‐induced secondary structure of substance P

C. Deber, G. Woolley, 1987, Biopolymers.

Central nervous system myelin: structure, function, and pathology

C. Deber, S. Reynolds, C M Deber, 1991, Clinical Biochemistry.

The structure of “unstructured” regions in peptides and proteins: Role of the polyproline II helix in protein folding and recognition *

Alan R Davidson, A. Rath, C. Deber, 2005, Biopolymers.

Role of the C-terminal carboxylate in peptide bond isomerism

C. Deber, 1978 .

Hypothesis about the function of membrane-buried proline residues in transport proteins.

C. Deber, C. Brandl, C M Deber, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Ligand-dependent quenching of tryptophan fluorescence in human erythrocyte hexose transport protein.

C. Deber, A. Pawagi, 1990, Biochemistry.

Synthesis and circular dichroism characterization of L‐azetidine‐2‐carboxylic acid cyclic peptides

C. Deber, R. Boni, A. S. Verdini, 1978 .

Cyclic peptides. IX. Conformations of a synthetic ion-binding cyclic peptide, cyclo-(pro-gly)3, from circular dichroism and 1H and 13C nuclear magnetic resonance.

E. Blout, C. Deber, V. Madison, 1974, Journal of the American Chemical Society.

Binding of human normal and multiple sclerosis-derived myelin basic protein to phospholipid vesicles: effects on membrane head group and bilayer regions.

P. Fraser, C. Deber, D. Hughes, 1986, Archives of biochemistry and biophysics.

Isosteric metal complexes of ionophore A23187

C. Deber, D. Pfeiffer, 1979, FEBS letters.

Ionophore A23187. Solution conformations of the calcium complex and free acid deduced from proton and carbon-13 nuclear magnetic resonance studies.

C. Deber, D. R. Pfieffer, 1976, Biochemistry.

Inside-out Signaling Promotes Dynamic Changes in the Carcinoembryonic Antigen-related Cellular Adhesion Molecule 1 (CEACAM1) Oligomeric State to Control Its Cell Adhesion Properties*

A. Rath, C. Deber, C. Yip, 2013, The Journal of Biological Chemistry.

δ-Regions in proteins: Helices mispredicted as transmembrane segments by the threshold hydrophobicity requirement

C. Deber, Li-ping Liu, Chen Wang, 2002 .

Guidelines for membrane protein engineering derived from de novo designed model peptides.

C. Deber, C M Deber, L P Liu, 1998, Biopolymers.

The structure and function of central nervous system myelin.

C. Deber, K. Williams, 1993, Critical reviews in clinical laboratory sciences.

Cation transport properties of a synthetic Ca2+-selective peptide ionophore in phospholipid and sarcoplasmic reticulum vesicles.

C. Deber, A. Drobnies, 1982, Biochimica et biophysica acta.

Folding proteins into membranes

C. Deber, N. Goto, 1996, Nature Structural Biology.

Transmembrane domain mediated self-assembly of major coat protein subunits from Ff bacteriophage.

C. Deber, R. Melnyk, A. Partridge, 2002, Journal of molecular biology.

A measure of helical propensity for amino acids in membrane environments

C. Deber, Shun-Cheng Li, Charles M. Deber, 1994, Nature Structural Biology.

Surface recognition elements of membrane protein oligomerization

A. Rath, C. Deber, 2008, Proteins.

Membrane protein assembly patterns reflect selection for non‐proliferative structures

A. Rath, C. Deber, 2007, FEBS letters.

Proline residues in transmembrane helices: structural or dynamic role?

C. Deber, K. Williams, Karen A. Williams, 1991, Biochemistry.

Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms

C. Deber, Y. Yau, V. Waters, 2018, Scientific Reports.

TM Finder: A prediction program for transmembrane protein segments using a combination of hydrophobicity and nonpolar phase helicity scales

A J Cuticchia, B. Muskat, A. Cuticchia, 2001, Protein science : a publication of the Protein Society.

Misfolding of the cystic fibrosis transmembrane conductance regulator and disease.

C. Deber, J. Cheung, Charles M Deber, 2008, Biochemistry.

Destabilization of the Transmembrane Domain Induces Misfolding in a Phenotypic Mutant of Cystic Fibrosis Transmembrane Conductance Regulator*

K. Du, G. Lukács, C. Deber, 2005, Journal of Biological Chemistry.

Conformational studies on 13C-enriched human and bovine myelin basic protein, in solution and incorporated into liposomes.

C. Deber, D. Wood, M. Moscarello, 1978, Biochemistry.

Missense mutations in transmembrane domains of proteins: Phenotypic propensity of polar residues for human disease

C. Deber, A. Therien, A. Partridge, 2004, Proteins.

Peptide-Based Efflux Pump Inhibitors of the Small Multidrug Resistance Protein from Pseudomonas aeruginosa

C. Deber, T. Stone, Chloe J. Mitchell, 2019, Antimicrobial Agents and Chemotherapy.

Structure of the EmrE multidrug transporter and its use for inhibitor peptide design

M. Karplus, C. Deber, V. Ovchinnikov, 2018, Proceedings of the National Academy of Sciences.

Enhanced proteolytic resistance of cationic antimicrobial peptides through lysine side chain analogs and cyclization.

C. Deber, M. Glibowicka, Shelley He, 2022, Biochemical and biophysical research communications.

Positive charge patterning and hydrophobicity of membrane-active antimicrobial peptides as determinants of activity, toxicity, and pharmacokinetic stability.

S. Sharpe, C. Deber, F. Khan, 2019, Journal of medicinal chemistry.

Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides.

C. Deber, T. Stone, Shelley He, 2021, Biochemistry.

Aromatic and cation-pi interactions enhance helix-helix association in a membrane environment.

Karen Hecht, C. Deber, Charles M Deber, 2007, Biochemistry.

Optimizing synthesis and expression of transmembrane peptides and proteins.

C. Deber, F. Cunningham, 2007, Methods.

Conformations of proline residues in membrane environments

C. Deber, M. Glibowicka, G. Woolley, 1990, Biopolymers.

Transfer of peptide hormones from aqueous to membrane phases

C. Deber, B. Behnam, 1985 .

Perspective: peptides as mimics of transmembrane segments in proteins.

C. Deber, L. P. Liu, C. Wang, 2008, The journal of peptide research : official journal of the American Peptide Society.

Modulation of the oligomerization of myelin proteolipid protein by transmembrane helix interaction motifs.

Derek P. Ng, Derek P Ng, C. Deber, 2010, Biochemistry.

R. Deber, C. Deber, C. Brandl, 1988, Biopolymers.

The Affinity of GXXXG Motifs in Transmembrane Helix-Helix Interactions Is Modulated by Long-range Communication*

D. Engelman, J. Bowie, Sanguk Kim, 2004, Journal of Biological Chemistry.

Disease-associated mutations in conserved residues of ALK-1 kinase domain

C. Deber, M. Letarte, U. Cymerman, 2003, European Journal of Human Genetics.

Relative role(s) of leucine versus isoleucine in the folding of membrane proteins

C. Deber, T. Stone, 2019 .

Structural impact of proline mutations in the loop region of an ancestral membrane protein

C. Deber, Vincent G. Nadeau, 2016, Biopolymers.

SDS micelles as a membrane-mimetic environment for transmembrane segments.

C. Deber, David V. Tulumello, 2009, Biochemistry.

Impact of cholesterol and Lumacaftor on the folding of CFTR helical hairpins.

C. Deber, M. Schlierf, G. Krainer, 2022, Biochimica et biophysica acta. Biomembranes.

Manipulation of peptide conformations by fine‐tuning of the environment and/or the primary sequence

C. Deber, P. Kim, Shun‐Cheng Li, 1995, Biopolymers.

Bilayer-stabilizing properties of myelin basic protein in dioleoylphosphatidylethanolamine systems.

P. Fraser, C. Deber, R. Rand, 1989, Biochimica et biophysica acta.

Heat treatment of thioredoxin fusions increases the purity of α‐helical transmembrane protein constructs

C. Deber, M. Schlierf, G. Krainer, 2021, Protein science : a publication of the Protein Society.

Peptides in membranes: Helicity and hydrophobicity

C. Deber, Shun‐Cheng Li, 1995, Biopolymers.

Interhelical hydrogen bonds in the CFTR membrane domain

C. Deber, A. Therien, Fiona E.M. Grant, 2001, Nature Structural Biology.

Viable transmembrane region mutants of bacteriophage M13 coat protein prepared by site-directed mutagenesis.

C. Deber, Z. Li, 1991, Biochemical and biophysical research communications.

Nucleotides bind to the C-terminus of ClC-5.

C. Deber, L. Huan, C. Bear, 2006, The Biochemical journal.

Combining hydrophobicity and helicity: a novel approach to membrane protein structure prediction.

C. Deber, C M Deber, L P Liu, 1999, Bioorganic & medicinal chemistry.

Val-->Ala mutations selectively alter helix-helix packing in the transmembrane segment of phage M13 coat protein.

C. Deber, M. Glibowicka, Z. Li, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of a PIP Binding Site in the N-Terminal Domain of V-ATPase a4 and Its Role in Plasma Membrane Association

C. Deber, R. Botelho, Yeqi Yao, 2023, International journal of molecular sciences.

Effects of a polar amino acid substitution on helix formation and aggregate size along the detergent-induced peptide folding pathway.

C. Deber, R. Prosser, P. Macdonald, 2013, Biochimica et biophysica acta.

Polar residue tagging of transmembrane peptides.

C. Deber, R. Melnyk, N. Goto, 2003, Biopolymers.

Peptide models of membrane protein folding.

A. Rath, C. Deber, David V. Tulumello, 2009, Biochemistry.

Protein structure in membrane domains.

A. Rath, C. Deber, 2012, Annual review of biophysics.

Efficiency of detergents at maintaining membrane protein structures in their biologically relevant forms.

C. Deber, David V. Tulumello, 2012, Biochimica et biophysica acta.

Drug Efflux by a Small Multidrug Resistance Protein Is Inhibited by a Transmembrane Peptide

Bradley E. Poulsen, C. Deber, 2012, Antimicrobial Agents and Chemotherapy.

Design, expression, and purification of de novo transmembrane “hairpin” peptides

C. Deber, Inga Isupov, David V. Tulumello, 2012, Biopolymers.

Positions of polar amino acids alter interactions between transmembrane segments and detergents.

C. Deber, David V. Tulumello, 2011, Biochemistry.

Beta-branched residues adjacent to GG4 motifs promote the efficient association of glycophorin A transmembrane helices.

Bradley E. Poulsen, C. Deber, Wilfred Ip, 2011, Biopolymers.

Complexation of Zn(II) to a native sequence tripeptide of human serum albumin studied by 13C nuclear magnetic resonance

C. Deber, B. Sarkar, Helen Lakusta, 1980 .

Peptide Mimics of the M13 Coat Protein Transmembrane Segment

C. Deber, Chen Wang, 2000, The Journal of Biological Chemistry.

Structure and dynamics of bacteriophage IKe major coat protein in MPG micelles by solution NMR.

L. Kay, C. Deber, K. Williams, 1996, Biochemistry.

Acrylamide concentration determines the direction and magnitude of helical membrane protein gel shifts

A. Rath, C. Deber, F. Cunningham, 2013, Proceedings of the National Academy of Sciences.

In Situ Mapping of Membranolytic Peptide-Membrane Interactions by Coupled Attenuated Total Reflection Fourier-Transform Infrared Spectroscopy-Atomic Force Microscopy (ATR-FTIR-AFM)

C. Deber, R. Epand, C. Yip, 2011 .

Peptide-Based Approach to Inhibition of the Multidrug Resistance Efflux Pump AcrB.

C. Deber, T. Stone, Eamonn Reading, 2020, Biochemistry.

Conformations of neurotensin in solution and in membrane environments studied by 2-D NMR spectroscopy.

C. Deber, G. Y. Xu, 2009, International journal of peptide and protein research.

Modulating Transmembrane α-Helix Interactions through pH-Sensitive Boundary Residues.

Derek P. Ng, C. Deber, 2016, Biochemistry.

Helix-helix interactions: is the medium the message?

Derek P. Ng, C. Deber, 2015, Structure.

Hydrophobicity and helicity of membrane-interactive peptides containing peptoid residues.

C. Deber, Yan-chun Tang, 2002, Biopolymers.

[4] Use of ionophores for manipulating intracellular ion concentrations

C. Deber, D. Pfeiffer, G. Woolley, 1995 .

Helix Induction in Antimicrobial Peptides by Alginate in Biofilms*

Celine Chan, C. Deber, L. Burrows, 2004, Journal of Biological Chemistry.

Conformational Aspects of Polypeptides. VII. Reversal of The Helical Sense of Poly-L-Aspartate Esters

C. Deber, M. Goodman, A. Felix, 1962 .

Conformational aspects of polypeptides. XI. The nitroaromatic effect

C. Deber, M. Goodman, A. Felix, 1963 .

Evidence for Assembly of Small Multidrug Resistance Proteins by a “Two-faced” Transmembrane Helix*

A. Rath, C. Deber, R. Melnyk, 2006, Journal of Biological Chemistry.

Modulation of Na,K-ATPase by the gamma subunit: studies with transfected cells and transmembrane mimetic peptides.

C. Deber, A. Therien, R. Blostein, 2003, The Journal of biological chemistry.

Interhelical Packing in Detergent Micelles FOLDING OF A CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CONSTRUCT*

C. Deber, A. Therien, 2002 .

Sequence hydropathy dominates membrane protein response to detergent solubilization.

A. Rath, C. Deber, Vincent G. Nadeau, 2012, Biochemistry.

Positional dependence of non-native polar mutations on folding of CFTR helical hairpins.

C. Deber, Hania Wehbi, G. Gasmi-Seabrook, 2008, Biochimica et biophysica acta.

a-Helical , but not ( 3-sheet , propensity of proline is determined by peptide environment

C. Deber, K. Williams, N. Goto, 2005 .

Threshold hydrophobicity dictates helical conformations of peptides in membrane environments.

C. Deber, N. Goto, S. C. Li, 1998, Biopolymers.

Cystic fibrosis transmembrane conductance regulator: expression and helicity of a double membrane‐spanning segment

A. Emili, C. Deber, Li-ping Liu, 1998, FEBS letters.

An irregularity in the transmembrane domain helix correlates with the rate of insulin receptor internalization.

C. Deber, S. Shoelson, S. C. Li, 1994, Biochemistry.

Blockade of G Protein-Coupled Receptors and the Dopamine Transporter by a Transmembrane Domain Peptide: Novel Strategy for Functional Inhibition of Membrane Proteins in Vivo

P. Seeman, B. O'dowd, C. Deber, 2003, Journal of Pharmacology and Experimental Therapeutics.

Membrane protein misassembly in disease.

Derek P. Ng, Derek P Ng, Bradley E. Poulsen, 2012, Biochimica et biophysica acta.

The position of the Gly-xxx-Gly motif in transmembrane segments modulates dimer affinity.

A. Rath, C. Deber, Rachel M. Johnson, 2006, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Association of carbon-13 enriched human encephalitogenic nonapeptide with a membrane surface.

C. Deber, M. Young, M. E. Young, 1979, The Journal of biological chemistry.

Influence of glycine residues on peptide conformation in membrane environments.

C. Deber, S. C. Li, 2009, International journal of peptide and protein research.

Conformation of proline residues in bacteriorhodopsin.

C. Deber, G. Y. Xu, B. Sorrell, 1990, Biochemical and biophysical research communications.

Structure and function of the proline-rich region of myelin basic protein.

P. Fraser, C. Deber, 1985, Biochemistry.

Design and Characterization of a Membrane Protein Unfolding Platform in Lipid Bilayers

C. Deber, Vincent G. Nadeau, Anqi Gao, 2015, PloS one.

Retention of native-like oligomerization states in transmembrane segment peptides: application to the Escherichia coli aspartate receptor.

C. Deber, R. Melnyk, A. Partridge, 2001, Biochemistry.

Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo.

G. von Heijne, C. Deber, Nina Schiller, 2016, Biochemistry.

Distinctions between Hydrophobic Helices in Globular Proteins and Transmembrane Segments as Factors in Protein Sorting*

A. Rath, C. Deber, Charles M. Deber, 2009, Journal of Biological Chemistry.

Membrane interactions of the hydrophobic segment of diacylglycerol kinase epsilon.

C. Deber, R. Epand, R. Epand, 2007, Biochimica et biophysica acta.

Self-association of the transmembrane domain of an anthrax toxin receptor.

Sanguk Kim, A. Rath, C. Deber, 2006, Journal of molecular biology.

Oligomerization of a peptide derived from the transmembrane region of the sodium pump gamma subunit: effect of the pathological mutation G41R.

C. Deber, A. Therien, 2002, Journal of molecular biology.

Expression and purification of two hydrophobic double-spanning membrane proteins derived from the cystic fibrosis transmembrane conductance regulator.

C. Deber, A. Therien, M. Glibowicka, 2002, Protein expression and purification.

Peptides as transmembrane segments: decrypting the determinants for helix-helix interactions in membrane proteins.

A. Rath, C. Deber, Rachel M. Johnson, 2007, Biopolymers.

Hydrophobic Interactions in Complexes of Antimicrobial Peptides with Bacterial Polysaccharides

C. Deber, L. Burrows, Celine Chan, 2007, Chemical biology & drug design.

Putting the β-breaks on membrane protein misfolding

C. Deber, A. Therien, 2002, Nature Structural Biology.

Polar mutations in membrane proteins as a biophysical basis for disease.

C. Deber, A. Therien, A. Partridge, 2002, Biopolymers.

Evidence for beta-turn analogs in proline peptides in the solid state. An infrared study.

C. Deber, 1974, Macromolecules.

3 Membrane protein folding in detergents

C. Deber, H. Tschesche, David V. Tulumello, 2011 .

Lipid solvation effects contribute to the affinity of Gly-xxx-Gly motif-mediated helix-helix interactions.

A. Rath, C. Deber, R. Melnyk, 2006, Biochemistry.

Structural basis for misfolding at a disease phenotypic position in CFTR: comparison of TM3/4 helix-loop-helix constructs with TM4 peptides.

C. Deber, Cory M. Mulvihill, 2012, Biochimica et biophysica acta.

Evidence for a folded conformation of methionine- and leucine-enkephalin in a membrane environment.

C. Deber, B. Behnam, 1984, The Journal of biological chemistry.

Hydrophobic Blocks Facilitate Lipid Compatibility and Translocon Recognition of Transmembrane Protein Sequences

G. von Heijne, C. Deber, Nina Schiller, 2015, Biochemistry.

Role of aromatic residues at the lipid-water interface in micelle-bound bacteriophage M13 major coat protein.

C. Deber, A. Davidson, C. Yuen, 2000, Biochemistry.

Helix-helix interactions between transmembrane α-helices 3 and 4 within the cystic fibrosis transmembrane conductance regulator protein

C. Deber, A. Partridge, 2002 .

Defining the defect in F508 del CFTR: a soluble problem?

A. Rath, C. Deber, J. Cheung, 2008, Chemistry & biology.

Prediction of protein transmembrane segments using a hydrophobicity scale derived from hydrophobic peptides

C. Deber, Li-ping Liu, Chen Wang, 2002 .

Correction factors for membrane protein molecular weight readouts on sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

A. Rath, C. Deber, 2013, Analytical biochemistry.

Peptide models for protein-mediated cation transport.

C. Deber, 1980, Canadian Journal of Biochemistry.

Minimum energy conformations of proline‐containing helices

C. Deber, A. Polinsky, K. Williams, 1992, Biopolymers.

Conformations of cyclic peptide/calcium complexes in solution

C. Deber, D. Hughes, 1982, Biopolymers.

Functional response of the small multidrug resistance protein EmrE to mutations in transmembrane helix 2

A. Rath, C. Deber, Jun Wang, 2014, FEBS letters.

Conformational interconversions of the cyclic hexapeptide cyclo(Pro-Gly) 3 .

E. Blout, D. Torchia, C. Deber, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Transmembrane domain of myelin protein zero can form dimers: possible implications for myelin construction.

Anthony W Partridge, James U Bowie, J. Bowie, 2007, Biochemistry.

Mutagenesis of bacteriophage IKe major coat protein transmembrane domain: role of an interfacial proline residue.

C. Deber, K. Williams, 1993, Biochemical and biophysical research communications.

A novel method for monitoring the cytosolic delivery of peptide cargo.

C. Deber, Patrick Kim Chiaw, C. Bear, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Efflux by Small Multidrug Resistance Proteins Is Inhibited by Membrane-interactive Helix-stapled Peptides*

Bradley E. Poulsen, C. Deber, K. Bellmann-Sickert, 2014, The Journal of Biological Chemistry.

Structural effects of extracellular loop mutations in CFTR helical hairpins.

C. Deber, C. Bear, M. Glibowicka, 2018, Biochimica et biophysica acta. Biomembranes.

Modulating Transmembrane α-Helix Interactions through pH-Sensitive Boundary Residues.

Derek P. Ng, C. Deber, 2016, Biochemistry.

31P NMR and HPLC Investigations of the Cyclophosphamide Metabolite, Phosphoramide Mustard

P. Fraser, C. Deber, S. Soldin, 1987 .

Evidence for stereospecific collision complexes of cyclo(tri‐L‐prolyl) with benzene

D. Torchia, C. Deber, 1972, Biopolymers.

Proline Residues in Proteins

C. Deber, B. Brodsky, 2001 .

Hydrophobic moment drives penetration of bacterial membranes by transmembrane peptides

C. Deber, T. S. Johnson, Aleksandra A Bourdine, 2023, The Journal of biological chemistry.

Proline residues in bacteriorhodopsin: Conformation and temperature dependence

C. Deber, B. Sorrell, Guang-Yi Xu, 1991 .

Letter: Long-range steric effects on rotational barriers in peptide chains.

R. E. Young, C. Deber, 1975, Biopolymers.

Putting the beta-breaks on membrane protein misfolding.

C. Deber, A. Therien, 2002, Nature structural biology.

Short Transmembrane Peptide Sequences as Nucleation Sites for Globular Protein Folding

A. Rath, C. Deber, Rachel M. Johnson, 2006 .