C. Bartram

J. Harbott, C. Bartram, W. Ludwig, 1993, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Acute lymphoblastic leukemia of childhood: identification of two distinct regions of deletion on the short arm of chromosome 12 in the region of TEL and KIP1.

M. Schrappe, C. Bartram, H. Koeffler, 1996, Blood.

Clinical significance of aberrant DNA methylation in childhood acute lymphoblastic leukemia.

M. Schrappe, C. Bartram, H. Koeffler, 2011, Leukemia research.

Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer.

K. Hemminki, A. Meindl, R. Schmutzler, 2006, Carcinogenesis.

Molecular analysis of the cyclin‐dependent kinase inhibitor family: p16(CDKN2/MTS1/INK4A), p18(INK4C) and p27(Kip1) genes in neuroblastomas

C. Bartram, H. Koeffler, N. Kawamata, 1996, Cancer.

Allelotype analysis of childhood acute lymphoblastic leukemia.

C. Bartram, H. Koeffler, C. Miller, 1995, Cancer research.

Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood.

C. Bartram, A. Tobler, C. Miller, 1995, Blood.

Linkage analysis in a large family with primary pulmonary hypertension: genetic heterogeneity and a second primary pulmonary hypertension locus on 2q31-32.

W. Seeger, C. Bartram, B. Janssen, 2002, Chest.

IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol

B. Meissner, J. Harbott, M. Schrappe, 2011 .

Mutation of the p53 gene in neuroblastoma and its relationship with N-myc amplification.

F. Berthold, C. Bartram, H. Koeffler, 1993, Cancer research.

The human c‐abl oncogene in the philadelphia translocation

J. Stephenson, N. Heisterkamp, J. Groffen, 1984, Journal of cellular physiology. Supplement.

Point Mutation of the ms Protooncogenes and Chromosome Aberrations in Acute Nonlymphocytic Leukemia and Preleukemia Related to Therapy with Alkylating Agents1

C. Bartram, J. Pedersen‐Bjergaard, J. Lyons, 2006 .

Cellular oncogenes in human teratocarcinoma cell lines.

H. Tesch, C. Bartram, D. Bronson, 1990, International journal of andrology.

Rearrangement and expression of myeov and hst in NIH/3T3 transfectants: a caveat for the interpretation of DNA transfection analyses.

C. Bartram, S. Luf, J. Janssen, 2007, Oncology reports.

Spectrum of transforming sequences detected by tumorigenicity assay in a large series of human neoplasms

C. Bartram, U. Siebers, J. Janssen, 1999, International journal of cancer.

Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood.

E. Papaemmanuil, J. Vijayakrishnan, R. Houlston, 2010, Blood.

Patients' age and BCR-ABL frequency in adult B-precursor ALL: a retrospective analysis from the GMALL study group.

E. Thiel, C. Bartram, D. Hoelzer, 2008, Blood.

A breast cancer risk haplotype in the caspase-8 gene.

N. Camp, L. Cannon-Albright, A. Cox, 2009, Cancer research.

PPARGC1A, PPARGC1B and EP300 with familial breast cancer

K. Hemminki, A. Meindl, R. Schmutzler, 2006 .

Identification of a novel putative Ran-binding protein and its close homologue.

M. Schäfer, C. Bartram, H. Hameister, 2000, Biochemical and biophysical research communications.

lymphoblastic leukemia genetic polymorphisms and susceptibility to childhood acute MTHFR

D. Labuda, Rajiv Kumar, B. Burwinkel, 2011 .

MTHFR genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia.

K. Hemminki, Rajiv Kumar, B. Burwinkel, 2005, Blood.

Single CpG hypermethylation, allele methylation errors, and decreased expression of multiple tumor suppressor genes in normal body cells of mutation‐negative early‐onset and high‐risk breast cancer patients

C. Sutter, C. Bartram, T. Haaf, 2018, International journal of cancer.

The translocation (6;9) (p23;q34) shows consistent rearrangement of two genes and defines a myeloproliferative disorder with specific clinical features.

A. Hagemeijer, C. Bartram, G. Grosveld, 1992, Blood.

Confirmation of the localization of the human recombination activating gene 1 (RAG1) to chromosome 11p13

K. Schwarz, K. Grzeschik, M. Gessler, 1994, Human Genetics.

Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease

D. Steinemann, P. Lichter, J. Harbott, 2008, Genes, chromosomes & cancer.

Clonal remissions in acute nonlymphocytic leukemia: evidence for a multistep pathogenesis of the malignancy.

C. Bartram, P. Fialkow, P. Fialkow, 1991, Blood.

Two novel missense and frameshift mutations in exons 5 and 6 of the purine nucleoside phosphorylase (PNP) gene in a severe combined immunodeficiency (SCID) patient

U. Pannicke, K. Schwarz, W. Friedrich, 1996, Human Genetics.

Brief Definitive Report

C. Bartram, 2022 .

Mutations in ras genes in myelocytic leukemias and myelodysplastic syndromes.

C. Bartram, 1988, Blood cells.

The acute lymphoblastic leukaemia cell line SEM with t(4;11) chromosomal rearrangement is biphenotypic and responsive to interleukin‐7

C. Bartram, R. Marschalek, G. Fey, 1994, British journal of haematology.

Localization of the human c-sis oncogene in Ph1-positive and Ph1- negative chronic myelocytic leukemia by in situ hybridization

A. Hagemeijer, N. Heisterkamp, J. Groffen, 1984 .

Five Polymorphisms and Breast Cancer Risk: Results from the Breast Cancer Association Consortium

M. Beckmann, P. Fasching, N. Camp, 2009, Cancer Epidemiology Biomarkers & Prevention.

Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

Patrick Neven, Hui Zhao, Nazneen Rahman, 2012, PloS one.

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

Daniel J. Park, S. Cross, M. Beckmann, 2012, PLoS ONE.

Bartram involvement of the J alpha cluster lymphoblastic leukemia : preferential usage of V delta 2 and frequent T-cell receptor delta gene recombination in common acute

Thomas, C. Bartram, Hansen-Hagge, 2003 .

Statement on the Genetic Diagnosis of Factors that Predispose to Multifactorial Diseases, Developmental Disorders, and Drug Reactions

K. Zerres, C. Bartram, W. Henn, 2004 .

"Intravascular lymphomatosis" (angioendotheliomatosis): evidence for a T-cell origin in two cases.

C. Bartram, G. Burg, G. Schuler, 1990, Human pathology.

Distinct gene expression proﬁles determine molecular treatment response in childhood acute lymphoblastic leukemia

B. Schäfer, C. Bartram, K. Welte, 2004 .

T lymphocytes lack rearrangement of the bcr gene in Philadelphia chromosome-positive chronic myelocytic leukemia

C. Bartram, P. Bettelheim, C. Stain, 1987 .

Point mutation of the ras protooncogenes and chromosome aberrations in acute nonlymphocytic leukemia and preleukemia related to therapy with alkylating agents.

C. Bartram, J. Pedersen‐Bjergaard, J. Lyons, 1988, Cancer research.

Immunoglobulin and T-cell receptor gene rearrangements in Hodgkin's disease.

C. Bartram, A. Raghavachar, T. Binder, 1988, Cancer research.

Molecular Biological Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia

C. Bartram, W. Ludwig, T. Seriu, 1997 .

Detection of minimal residual leukemia by polymerase chain reactions.

C. Bartram, T. Hansen-Hagge, S. Yokota, 1990, Bone marrow transplantation.

MINIMAL RESIDUAL LEUKAEMIA IN CHRONIC MYELOID LEUKAEMIA PATIENTS AFTER T-CELL DEPLETED BONE-MARROW TRANSPLANTATION

C. Bartram, J. Lyons, R. Arnold, 1989, The Lancet.

Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood.

C. Bartram, C. Miller, M. Hachiya, 1993, Blood.

Regional mapping of the human immunoglobulin lambda light chain to the Philadelphia chromosome in chronic myeloid leukaemia.

C. Bartram, G. Grosveld, A. de Klein, 1984, Leukemia research.

P53 mutations in myelodysplastic syndromes.

A. Schulz, C. Bartram, K. Grünewald, 1992, Leukemia.

Isochromosome 17q in Ph1-negative leukemia: a clinical, cytogenetic, and molecular study.

C. Bartram, R. Becher, F. Carbonell, 1990, Blood.

Persistence of CML despite deletion of rearranged bcr/c-abl sequences.

C. Bartram, R. Becher, J. Janssen, 1987, Haematology and blood transfusion.

Involvement of chromosome 9 in variant Ph1 translocation.

C. Bartram, E. Kleihauer, B. Anger, 1985, Leukemia research.

Is the chromosomal region 9q34 always involved in variants of the Ph1 translocation?

A. Hagemeijer, C. Bartram, D. Bootsma, 1984, Cancer genetics and cytogenetics.

Localization of the human c-sis oncogene in Ph1-positive and Ph1-negative chronic myelocytic leukemia by in situ hybridization.

A. Hagemeijer, N. Heisterkamp, J. Groffen, 1984, Blood.

Treatment of Adult ALL according to protocols of the German Multicenter Study Group for Adult ALL (GMALL).

T. Lipp, E. Thiel, A. Ganser, 2000, Hematology/oncology clinics of North America.

The single nucleotide polymorphism IVS1+309 in mouse double minute 2 does not affect risk of familial breast cancer.

P. Bugert, K. Hemminki, A. Meindl, 2006, Cancer research.

The Single Nucleotide Polymorphism IVS 1 + 309 in Mouse Double Minute 2 Does Not Affect Risk of Familial Breast Cancer

P. Bugert, K. Hemminki, A. Meindl, 2006 .

Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia Patients by Polymerase Chain Reactions

C. Bartram, A. Biondi, T. Hansen-Hagge, 1992 .

T-cell receptor delta gene recombination in common acute lymphoblastic leukemia: preferential usage of V delta 2 and frequent involvement of the J alpha cluster

C. Bartram, T. Hansen-Hagge, S. Yokota, 1991 .

Aberrant methylation in promoter-associated CpG islands of multiple genes in relapsed childhood acute lymphoblastic leukemia.

J. V. van Dongen, C. Bartram, H. Koeffler, 2004, Oncology reports.

Reliability of BCR-ABL RT-PCR in Adult Acute B-Lineage Lymphoblastic Leukemia: Results of Confirmational PCR

C. Bartram, C. Schoch, C. Fonatsch, 2003 .

The fusion of TEL and ABL in human acute lymphoblastic leukaemia is a rare event

C. Bartram, W. Ludwig, C. Fonatsch, 1995, British journal of haematology.

Detection of minimal residual leukemia by the polymerase chain reaction: potential implications for therapy.

C. Bartram, 1993, Clinica chimica acta; international journal of clinical chemistry.

Molecular genetic techniques for detection of minimal residual disease in acute lymphoblastic leukemia: possibilities and limitations.

C. Bartram, 1993, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Detection of minimal residual leukemia by polymerase chain reactions: potential implications for therapy

C. Bartram, J. Janssen, T. Hansen-Hagge, 1992 .

Ambiguous phenotypes and genotypes in 16 children with acute leukemia as characterized by multiparameter analysis.

W. Hiddemann, J. Harbott, C. Bartram, 1988, Blood.

bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia.

A. Hagemeijer, M. Greaves, C. Bartram, 1986, Blood.

Loss of ras oncogene mutation in a myelodysplastic syndrome after low-dose cytarabine therapy.

G. Mufti, C. Bartram, J. Lyons, 1988, The New England journal of medicine.

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.

D. Steinemann, M. Muckenthaler, R. Houlston, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Aberrant methylation in promoter-associated CpG islands of multiple genes in acute lymphoblastic leukemia.

J. V. van Dongen, C. Bartram, W. Hofmann, 2006, Leukemia research.

Methylation analysis of asparagine synthetase gene in acute lymphoblastic leukemia cells

C. Bartram, W. Hofmann, H. Koeffler, 2006, Leukemia.

myelodysplastic syndromes, and cell lines leukemias, retinoic acid-resistant acute promyelocytic leukemias, Infrequent alterations of the RAR alpha gene in acute myelogenous

Carl W. Miller, P. Pelicci, C. Bartram, 2011 .

Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment

M. Schrappe, C. Bartram, C. Eckert, 2011, Leukemia.

Allelotype analysis in relapsed childhood acute lymphoblastic leukemia

C. Bartram, J. Dongen, H. Koeffler, 2003, Oncogene.

Establishment and characterization of a new Epstein-Barr virus transformed cell line from a human B cell lymphoma

H. Heimpel, M. Pawlita, C. Bartram, 1990, Blut.

11q13 is a susceptibility locus for hormone receptor positive breast cancer

Patrick Neven, Michael Jones, Michael Bremer, 2012, Human mutation.

Genetic polymorphisms in the tumour necrosis factor locus in childhood acute lymphoblastic leukaemia

M. Schrappe, C. Bartram, H. Koeffler, 2002, British journal of haematology.

Amplification and expression of the N-myc gene in neuroblastoma

F. Berthold, C. Bartram, 1987, European Journal of Pediatrics.

Evolution of tumor cytogenetic aberrations and N-myc oncogene amplification in a case of disseminated neuroblastoma.

J. Harbott, C. Bartram, F. Lampert, 1987, Cancer genetics and cytogenetics.

Twenty‐three novel BRCA1 and BRCA2 sequence alterations in breast and/or ovarian cancer families in Southern Germany

C. Bartram, R. Klaes, P. Meyer, 2003, Human mutation.

Activation of proto-oncogenes in human leukemias

C. Bartram, 1985, Blut.

Molecular Genetic Changes as Indicators of Therapeutic Effectiveness

C. Bartram, 1989 .

bcr rearrangement and translocation of the c-abl oncogene in Philadelphia positive acute lymphoblastic leukemia.

A. Hagemeijer, M. Greaves, C. Bartram, 1986, Blood.

DDX3X mutations in two girls with a phenotype overlapping Toriello–Carey syndrome

R. Eils, M. Schlesner, C. Evers, 2017, American journal of medical genetics. Part A.

Molecular analysis of the secretory phospholipase A2 gene, a candidate of Mom1 gene, in neuroblastomas.

C. Bartram, H. Koeffler, N. Kawamata, 1997, Cancer letters.

The translocation (6;9) (p23;q34) shows consistent rearrangement of two genes and defines a myeloproliferative disorder with specific clinical features

A. Hagemeijer, C. Bartram, G. Grosveld, 1992 .

Impact of Minimal Residual Disease (MRD) on Prognosis in Children with Acute Lymphoblastic Leukemia (ALL) According to WBC Count, Age and TEL/AML1 Status at Diagnosis. Results of the AIEOP-BFM ALL 2000 Study.

M. Schrappe, C. Bartram, M. Valsecchi, 2007 .

CD7+ and CD56+ Acute Myelogenous Leukemia is a Distinct Biologic and Clinical Disease Entity

C. Bartram, A. Franke, K. Jentsch‐Ullrich, 2001 .

Molecular genetic analysis of DNA obtained from fixed, air dried or paraffin embedded sources

C. Bartram, K. Grünewald, H. Feichtinger, 1991, Annals of Hematology.

Molecular analysis of the cyclin-dependent kinase inhibitor genes, p15, p16, p18 and p19 in the myelodysplastic syndromes.

C. Bartram, H. Koeffler, C. Miller, 1997, Leukemia research.

Clinical Relevance of Chromosomal Aberrations in Childhood ALL: Cytogenetic Data of the German Therapy Studies

A. Borkhardt, J. Harbott, C. Bartram, 1994 .

Acute undifferentiated leukemia: implications for cellular origin and clonality suggested by analysis of surface markers and immunoglobulin gene rearrangement.

A. Ganser, C. Bartram, G. Heil, 1986, Blood.

Benzo[a]pyrene 4,5-oxide. Discrepancy between induction of sister chromatid exchange and binding to DNA in cultured human fibroblasts.

H. Glatt, F. Oesch, C. Bartram, 1980, Biochimica et biophysica acta.

An oncogenic fusion product of the phosphatidylinositol 3-kinase p85β subunit and HUMORF8, a putative deubiquitinating enzyme

A. Schulz, C. Bartram, J. Janssen, 1998, Oncogene.

Molecular diagnosis of type 1c glycogen storage disease

C. Bartram, B. Janssen, E. Mayatepek, 1999, Human Genetics.

Confirmation of 5p12 As a Susceptibility Locus for Progesterone-Receptor–Positive, Lower Grade Breast Cancer

S. Cross, M. Beckmann, P. Fasching, 2011, Cancer Epidemiology, Biomarkers & Prevention.

The murine ufo receptor: molecular cloning, chromosomal localization and in situ expression analysis.

A. Schulz, C. Bartram, H. Hameister, 1992, Oncogene.

Acute lymphoblastic leukemia in children: treatment planning via minimal residual disease assessment.

M. Schrappe, C. Bartram, A. Schrauder, 2012, Deutsches Arzteblatt international.

Phenotypic and genotypic heterogeneity in infant acute leukemia. I. Acute lymphoblastic leukemia.

J. Harbott, O. Haas, C. Bartram, 1989, Leukemia.

Position paper: Cornerstones for an ethically and legally informed practice of whole genome sequencing

R. Eils, P. Kirchhof, P. Schirmacher, 2015 .

Clonal Hematopoiesis as Defined by Polymorphic X-Linked Loci Occurs Infrequently in Aplastic Anemia

A. Schulz, C. Bartram, H. Schrezenmeier, 1995 .

Clonal hematopoiesis as defined by polymorphic X-linked loci occurs infrequently in aplastic anemia.

A. Schulz, C. Bartram, T. Dexter, 1995, Blood.

The ATM gene and susceptibility to childhood T‐cell acute lymphoblastic leukaemia

C. Bartram, H. Koeffler, H. Taguchi, 1998, British journal of haematology.

Brief report Veriﬁcation of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood

E. Papaemmanuil, M. Greaves, J. Vijayakrishnan, 2010 .

Chromosome-positive Chronic Myelocytic Leukemia T Lymphocytes Lack Rearrangement of the Bcr Gene in Philadelphia

C. Bartram, 2005 .

Additional c-abl/bcr rearrangements in a CML patient exhibiting two ph1 chromosomes during blast crisis.

A. Hagemeijer, C. Bartram, G. Grosveld, 1986, Leukemia research.

C‐abl and bcr are rearranged in a Ph1‐negative CML patient.

N. Heisterkamp, J. Groffen, C. Bartram, 1985, The EMBO journal.

Oncogenetic aspects of chronic myelocytic leukemia.

C. Bartram, G. Grosveld, A. de Klein, 1985, Haematology and blood transfusion.

Molecular response of CML patients treated with interferon‐α monitored by quantitative Southern blot analysis

H. Heimpel, C. Bartram, A. Reiter, 1997 .

Infrequent alterations of the RAR alpha gene in acute myelogenous leukemias, retinoic acid-resistant acute promyelocytic leukemias, myelodysplastic syndromes, and cell lines.

P. Pelicci, C. Bartram, H. Koeffler, 1996, Blood.

Molecular response of CML patients treated with interferon-alpha monitored by quantitative Southern blot analysis. German chronic myeloid leukaemia (CML) Study Group.

H. Heimpel, C. Bartram, A. Reiter, 1997, British journal of haematology.

The functional genetic variant Ile646Val located in the kinase binding domain of the A-kinase anchoring protein 10 is associated with familial breast cancer.

K. Hemminki, A. Meindl, R. Schmutzler, 2006, Carcinogenesis.

Acute undifferentiated leukemia: implications for cellular origin and clonality suggested by analysis of surface markers and immunoglobulin gene rearrangement.

A. Ganser, C. Bartram, G. Heil, 1986, Blood.

Aristolochic Acid I Induced Tumors in Wistar Rats Contain Activating Mutations in Codon 61 of the H-ras Protooncogene

C. Bartram, M. Wiessler, H. Schmeiser, 1989 .

t(5;14)(q33-34;q11), a new recurring cytogenetic abnormality in childhood acute leukemia.

J. Harbott, C. Bartram, W. Ludwig, 1994, Leukemia.

Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk

James Allan, E. Papaemmanuil, J. Vijayakrishnan, 2010, Nature Genetics.

[Chromosomal abnormalities in human neoplasia (author's transl)].

C. Bartram, H. Rüdiger, 1978, Klinische Wochenschrift.

The proximal element of the beta globin locus control region is not functionally required in vivo.

C. Bartram, A. Kulozik, E. Kohne, 1991, The Journal of clinical investigation.

Clonal analysis of human leukemias by molecular genetic approaches.

C. Bartram, J. Janssen, J. W. Janssen, 1990, Haematology and blood transfusion.

ras gene mutations and clonal analysis using RFLPs of X-chromosome genes in myelodysplastic syndromes.

C. Bartram, M. Buschle, J. Lyons, 1989, Haematology and blood transfusion.

Prethymic phenotype and genotype of pre-T (CD7+/ER-)-cell leukemia and its clinical significance within adult acute lymphoblastic leukemia.

E. Thiel, A. Ganser, C. Bartram, 1989, Blood.

A non-enzymatic function of 17β-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

K. Kavanagh, R. Wanders, C. Bartram, 2010, EMBO molecular medicine.

Mapping of the oncogenes Myc, Sis, and int-1 to the distal part of mouse chromosome 15.

C. Bartram, H. Hameister, S. Adolph, 1987, Cytogenetics and cell genetics.

19p13.1 is a triple-negative-specific breast cancer susceptibility locus.

Daniel J. Park, Julian Peto, Kamila Czene, 2012, Cancer research.

TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia.

H P Koeffler, T. Golub, D. Neuberg, 1996, Blood.

Evaluation of the cytogenetic aberration pattern in amyloid light chain amyloidosis as compared with monoclonal gammopathy of undetermined significance reveals common pathways of karyotypic instability.

D. Hose, H. Goldschmidt, A. Jauch, 2008, Blood.

Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1.

H. Hammes, C. Bartram, C. Fischer, 2005, Diabetes.

Functional deficiency of fibroblasts heterozygous for Bloom syndrome as specific manifestation of the primary defect.

C. Bartram, H. Rüdiger, E. Passarge, 1981, American journal of human genetics.

Rate of sister chromatid exchanges in Bloom syndrome fibroblasts reduced by co-cultivation with normal fibroblasts.

C. Bartram, H. Rüdiger, W. Harder, 1980, American journal of human genetics.

DNA repair: Pathways and defects

C. Bartram, 1980, European Journal of Pediatrics.

Frequency of sister chromatid exchanges in Bloom syndrome fibroblasts reduced by cocultivation with normal cells

C. Bartram, H. Rüdiger, E. Passarge, 1979, Human Genetics.

Chromatid exchanges in ataxia telangiectasia, Bloom syndrome, Werner syndrome, and xeroderrna pigmentosum

C. Bartram, E. Passarge, T. Koske-Westphal, 1976, Annals of human genetics.

Somatic recombination as possible prelude to malignant transformation.

C. Bartram, E. Passarge, 1976, Birth defects original article series.

Oncogenes: Clues to carcinogenesis

C. Bartram, 2004, European Journal of Pediatrics.

Moleculargenetic Analyses of Chronic Myelocytic Leukemia

C. Bartram, 1988 .

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

J. Stephenson, N. Heisterkamp, J. Groffen, 1984, Cell.

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

J. Stephenson, A. Hagemeijer, N. Heisterkamp, 1982, Nature.

Mutagen-induced sister chromatid exchange rate in Bloom syndrome remains unaltered in the presence of Bloom corrective factor

C. Bartram, H. Rüdiger, U. Schmidt-Preuss, 1981, Human Genetics.

Clinical and molecular characterization of the BRCA2 p.Asn3124Ile variant reveals substantial evidence for pathogenic significance

A. Schneeweiss, P. Bugert, M. Golatta, 2014, Breast Cancer Research and Treatment.

Infrequent Alterations of the RARa Gene in Acute Myelogenous Leukemias , Retinoic Acid-Resistant Acute Promyelocytic Leukemias , Myelodysplastic Syndromes , and Cell Lines

Carl W. Miller, P. Pelicci, C. Bartram, 2002 .

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

J. Stephenson, N. Heisterkamp, J. Groffen, 1983, Nature.

Rapid and non‐radioactive prenatal diagnosis of β thalassaemia and sickle cell disease: application of the polymerase chain reaction (PCR)

C. Bartram, A. Kulozik, E. Kohne, 1988, British journal of haematology.

ConvenientScreeningfor Hemoglobin Variantsby Usingthe DiamatHPLCSystem

C. Bartram, E. Kohne, J. Lyons, 1990 .

A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk

P. Bugert, K. Hemminki, A. Meindl, 2010, Breast Cancer Research and Treatment.

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study.

David T. W. Jones, F. Westermann, B. Burkhardt, 2016, European journal of cancer.

BRIP1 (BACH1) variants and familial breast cancer risk: a case-control study

Alfons Meindl, Barbara Burwinkel, Peter Bugert, 2007, BMC Cancer.

Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification

Katherine M. Tucker, Sebastian A. Wagner, Kelly J. Sullivan, 2019, Human Mutation.

SNPs in ultraconserved elements and familial breast cancer risk.

P. Bugert, K. Hemminki, A. Meindl, 2009, Carcinogenesis.

Comparative genomic hybridization analysis of Japanese B-cell chronic lymphocytic leukemia: correlation with clinical course

A. Jauch, C. Bartram, M. Tomonaga, 2006, Leukemia & lymphoma.

ras Oncogenes in Myelodysplastic Syndromes

C. Bartram, D. Layton, 1992 .

Mutation of Ki-ras and N-ras oncogenes in myelodysplastic syndromes.

G. Mufti, C. Bartram, J. Lyons, 1988, Blood.

Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray

Martin Zimmermann, Carl W. Miller, Rolf Koehler, 2008, Proceedings of the National Academy of Sciences.

Molecular and clinical characterization of an in frame deletion of uncertain clinical significance in the BRCA2 gene

A. Schneeweiss, P. Bugert, M. Golatta, 2012, Breast Cancer Research and Treatment.

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response.

M. Muckenthaler, P. Lichter, S. Pfister, 2009, Blood.

Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia.

B. Meissner, I. Heřmanová, A. Teigler‐Schlegel, 2014, Human molecular genetics.

The association between breast cancer and S100P methylation in peripheral blood by multicenter case–control studies

A. Schneeweiss, P. Bugert, M. Golatta, 2017, Carcinogenesis.

Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia.

J. V. van Dongen, V. V. D. van der Velden, C. Bartram, 2002, Best practice & research. Clinical haematology.

Philadelphia chromosome-positive (Ph+) childhood acute lymphoblastic leukemia: good initial steroid response allows early prediction of a favorable treatment outcome.

F Lampert, J. Harbott, M. Schrappe, 1998, Blood.

Chromosome-Positive ( Ph 1 ) Childhood Acute Lymphoblastic Leukemia : Good Initial Steroid Response Allows Early Prediction of a Favorable Treatment Outcome

J. Harbott, M. Schrappe, C. Bartram, 1998 .

Comparative genomic hybridization in childhood acute lymphoblastic leukemia: correlation with interphase cytogenetics and loss of heterozygosity analysis.

A. Jauch, B. Schoell, A. Teigler‐Schlegel, 2001, Cancer genetics and cytogenetics.

Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

J. Stephenson, A. Hagemeijer, M. Ferguson-Smith, 1983, Nature.

Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: results of the German multicenter trials GMALL 03/87 and 04/89.

E. Thiel, U. Aydemir, C. Bartram, 1998, Blood.

A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women.

P. Bugert, K. Hemminki, A. Meindl, 2009, Carcinogenesis.

Incidence and prognostic significance of immunophenotypic subgroups in childhood acute lymphoblastic leukemia: experience of the BFM study 86.

E. Thiel, J. Harbott, C. Bartram, 1993, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk

M. Loh, M. Relling, C. Pui, 2019, Nature Communications.

PCR as a Diagnostic Tool in ALL: A Comparison Between Cytogenetic and Polymerase Chain Reaction Analysis in Pediatric Patients with Acute Lymphoblastic Leukemia

T. Lion, J. Harbott, O. Haas, 1994 .

childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study Late MRD response determines relapse risk overall and in subsets of

B. Schäfer, M. Schrappe, C. Bartram, 2013 .

Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome

B. Meissner, A. Teigler‐Schlegel, M. Schrappe, 2012, Haematologica.

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

J. V. van Dongen, B. Schäfer, M. Schrappe, 2011, Blood.

Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia.

S. Ogawa, J. Harbott, M. Schrappe, 2009, International journal of oncology.

Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray.

Carl W. Miller, S. Ogawa, K. Hemminki, 2007, Blood.

Minimal requirements for the diagnosis, classification, and evaluation of the treatment of childhood acute lymphoblastic leukemia (ALL) in the "BFM Family" Cooperative Group.

W. Kamps, J. Harbott, O. Haas, 1992, Medical and pediatric oncology.

Homozygous Deletion of the p16 Gene in Childhood Acute Lymphoblastic Leukemia

Carl W. Miller, C. Bartram, A. Tobler, 1997 .

Breast cancer in young women (≤35 years): Genomic aberrations detected by comparative genomic hybridization

A. Jauch, G. Bastert, U. Mansmann, 2003, International journal of cancer.

Prognostic significance of additional chromosome abnormalities in adult patients with Philadelphia chromosome positive acute lymphoblastic leukaemia

E. Thiel, C. Bartram, W. Ludwig, 1996, British journal of haematology.

The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1

C. Evers, C. Bartram, Angela Schulz, 2019, Front. Physiol..

Impact of clinical exomes in neurodevelopmental and neurometabolic disorders.

Roland Eils, Stefan Wiemann, Ute Moog, 2017, Molecular genetics and metabolism.

Diagnosis of CoPAN by whole exome sequencing: Waking up a sleeping tiger's eye

R. Eils, C. Evers, C. Bartram, 2017, American journal of medical genetics. Part A.

Exome sequencing reveals a novel CWF19L1 mutation associated with intellectual disability and cerebellar atrophy

M. Schlesner, C. Evers, C. Bartram, 2016, American journal of medical genetics. Part A.

Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation.

C. Bartram, Y. Matsuo, H. Koeffler, 1999, Blood.

NEOPLASIA Loss of p 73 Gene Expression in Leukemias / Lymphomas Due to Hypermethylation

Carl W. Miller, C. Bartram, Y. Matsuo, 1999 .

Concurrent mutations in two different ras genes in acute myelocytic leukemias.

C. Bartram, J. Lyons, J. Janssen, 1987, Nucleic acids research.

Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis.

J. Chang-Claude, J. Hopper, A. Spurdle, 2008, Journal of the National Cancer Institute.

DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA

T. Holland-Letz, A. Schneeweiss, P. Bugert, 2016, Oncotarget.

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

Mads Thomassen, Nina Ditsch, Muhammad Usman Rashid, 2015, JAMA.

High frequency of Ki‐ras codon 12 mutations in pancreatic adenocarcinomas

C. Bartram, K. Grünewald, J. Lyons, 1989, International journal of cancer.

RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes.

C. Bartram, J. Bos, J. Lyons, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Ras mutations in Hodgkin's disease.

H. Tesch, C. Bartram, H. Drexler, 1988, Leukemia.

V(D)J recombination pathology.

K. Schwarz, C. Bartram, K. Schwarz, 1996, Advances in immunology.

Activation of gef‐h1, a guanine nucleotide exchange factor for RhoA, by DNA transfection

C. Bartram, John G. Collard, S. Luf, 2005, International journal of cancer.

Aristolochic acid activates ras genes in rat tumors at deoxyadenosine residues.

C. Bartram, A. Buchmann, J. Lyons, 1990, Cancer research.

Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32).

A. Jauch, P. L. Bergsagel, E. Schuuring, 2000, Blood.

Immunophenotypic and Genotypic Features , Clinical Characteristics , and Treatment Outcome of Adult ProB Acute Lymphoblastic Leukemia : Results of the German Multicenter Trials

E. Thiel, C. Bartram, W. Ludwig, 1998 .

New Possibilities for Cytogenetic Analysis of Leukemic Cells

A. Hagemeijer, C. Bartram, H. Adriaansen, 1986 .

Mutations of p53 in Wilms' tumors.

C. Bartram, H. Koeffler, S. Schneider, 1995, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

B. Schäfer, M. Schrappe, C. Bartram, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The spectrum of CFTR mutations in south-west German cystic fibrosis patients

C. Bartram, A. Kulozik, E. Kleihauer, 1992, Human Genetics.

Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis.

T. Lipp, E. Thiel, C. Bartram, 2002, Blood.

Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies.

E. Thiel, A. Ganser, C. Bartram, 2012, Blood.

Validation of Minimal Residual Disease as Surrogate Endpoint for Event-Free Survival in Childhood Acute Lymphoblastic Leukemia

B. Wood, M. Schrappe, C. Bartram, 2018, JNCI cancer spectrum.

Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.

J. Harbott, M. Schrappe, C. Bartram, 2016, Blood.

Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood

W. Hop, W. Kamps, J. V. van Dongen, 1998, The Lancet.

Association of prolactin and its receptor gene regions with familial breast cancer.

K. Hemminki, A. Meindl, R. Schmutzler, 2006, The Journal of clinical endocrinology and metabolism.

Clonal variation in childhood acute lymphoblastic leukaemia at early and late relapse detected by analyses of phenotype and genotype

C. Bartram, W. Ludwig, A. Raghavachar, 1988, European Journal of Pediatrics.

Spontaneous Epstein-Barr virus transformed B-cell line sharing the identical immunoglobulin gene rearrangement with acute myeloid leukemia.

H. Gerhartz, E. Thiel, W. Wilmanns, 1989, Blood.

A variant affecting miRNAs binding in the circadian gene Neuronal PAS domain protein 2 (NPAS2) is not associated with breast cancer risk

Hongbing Shen, Jin-hai Tang, Zhibin Hu, 2011, Breast Cancer Research and Treatment.

Intratumoral genomic heterogeneity in advanced head and neck cancer detected by comparative genomic hybridization.

A. Jauch, K. Hörmann, C. Bartram, 2003, Cancer genetics and cytogenetics.

Ethical framework for previously collected biobank samples

Joakim Dillner, Gert Helgesson, J. Carlson, 2007, Nature Biotechnology.

Acute leukemia with chromosome translocation (4; 11): 7 new patients and analysis of 71 cases

J. Harbott, C. Bartram, W. Ludwig, 1987, Blut.

MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas

Yutaka Shimada, Masayuki Imamura, Masakazu Ueda, 2002, Journal of Human Genetics.

Immunoglobulin and T-Cell Receptor Gene Rearrangements in Human Acute Leukemias

C. Bartram, C. Bartram, B. Kubanek, 1986 .

Biallelic heavy chain immunoglobulin gene rearrangement in acute nonlymphocytic leukemia

H. Heimpel, C. Bartram, A. Raghavachar, 1986, Blut.

Immunoglobulin and T cell receptor gene rearrangements in acute leukemias.

C. Bartram, E. Kleihauer, B. Kubanek, 1987, Haematology and blood transfusion.

Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia.

E. Thiel, C. Bartram, C. Pott, 2006, Blood.

Salvage Therapy of Adult ALL

N. Schmitz, E. Thiel, W. Hiddemann, 1996 .

Comparative genomic hybridization analysis in adult T-cell leukemia/lymphoma: correlation with clinical course.

A. Jauch, C. Bartram, M. Tomonaga, 2001, Blood.

leukemia / lymphoma : correlation with clinical course Comparative genomic hybridization analysis in adult T-cell

A. Jauch, C. Bartram, M. Tomonaga, 2001 .

Mutation of the ms Protooncogenes and Chromosome Aberrations in Acute Nonlymphocytic Leukemia and Preleukemia Related to Therapy with Alkylating Agents 1

C. Bartram, J. Pedersen‐Bjergaard, J. Lyons, 2006 .

Copy number variant in the candidate tumor suppressor gene MTUS1 and familial breast cancer risk.

Alfons Meindl, Barbara Burwinkel, Peter Bugert, 2007, Carcinogenesis.

Interaction of Werner and Bloom syndrome genes with p53 in familial breast cancer.

Dieter Niederacher, Alfons Meindl, Barbara Burwinkel, 2005, Carcinogenesis.

Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia by In Vitro Amplification of Rearranged T-Cell Receptor Chain Sequences

C. Bartram, T. Hansen-Hagge, S. Yokota, 2005 .

Chromosomal aberrations in follicular non-Hodgkin lymphomas of Japanese patients, detected with comparative genomic hybridization and polymerase chain reaction analysis.

J. D'haese, A. Jauch, C. Bartram, 2005, Cancer genetics and cytogenetics.

Association of death receptor 4 haplotype 626C-683C with an increased breast cancer risk.

P. Bugert, K. Hemminki, A. Meindl, 2005, Carcinogenesis.

Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia.

M. Schrappe, C. Bartram, M. Eichelbaum, 2005, JAMA.

Lymphocyte capping in muscular dystrophies

C. Bartram, D. Reinhardt, W. Mortier, 1982, Brain and Development.

Genetic variation at CYP 3 A is associated with age at menarche and breast cancer risk : a case-control study

Jaana M. Hartikainen, S. Cross, M. Beckmann, 2014 .

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

Patrick Neven, Chiun-Sheng Huang, Julian Peto, 2014, Breast Cancer Research.

Association of the ARLTS1 Cys148Arg variant with familial breast cancer risk

P. Bugert, K. Hemminki, A. Meindl, 2006, International journal of cancer.

FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor.

Eliseos J. Mucaki, F. Couch, B. Bonanni, 2015, Human molecular genetics.

9q31.2-rs865686 as a Susceptibility Locus for Estrogen Receptor-Positive Breast Cancer: Evidence from the Breast Cancer Association Consortium

S. Cross, R. Schulz-Wendtland, M. Beckmann, 2012, Cancer Epidemiology, Biomarkers & Prevention.

A 15q24 microdeletion in transient myeloproliferative disease (TMD) and acute megakaryoblastic leukaemia (AMKL) implicates PML and SUMO3 in the leukaemogenesis of TMD/AMKL

P. Bork, J. Korbel, A. Jauch, 2012, British journal of haematology.

Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

M. Beckmann, P. Fasching, N. Rahman, 2009, Journal of the National Cancer Institute.

Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history

A. Meindl, R. Schmutzler, M. Kiechle, 2018, BMC Cancer.

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia

E. Froňková, M. Schrappe, C. Bartram, 2016, British journal of haematology.

Mutations in the gene for the common gamma chain (γc) in X-linked severe combined immunodeficiency

K. Schwarz, W. Friedrich, C. Bartram, 1998, Human Genetics.

Dexamethasone in Induction Can Eliminate One Third of All Relapses in Childhood Acute Lymphoblastic Leukemia (ALL): Results of An International Randomized Trial in 3655 Patients (Trial AIEOP-BFM ALL 2000)

M. Schrappe, C. Bartram, M. Valsecchi, 2008 .

Immune thrombocytopenia more than a year after allogeneic marrow transplantation due to antibodies against donor platelets with anti‐PIA1 specificity: evidence for a host‐derived immune reaction

O. Haas, C. Bartram, K. Lechner, 1989, British journal of haematology.

Identification and prioritisation of causal variants in human genetic disorders from exome or whole genome sequencing data

R. Eils, S. Wiemann, M. Schlesner, 2017, bioRxiv.

So rare we need to hunt for them: reframing the ethical debate on incidental findings

C. von Kalle, R. Eils, S. Wiemann, 2015, Genome Medicine.

Influence of graft-versus-host disease on the eradication of minimal residual leukemia detected by polymerase chain reaction in chronic myeloid leukemia patients after bone marrow transplantation.

H. Heimpel, C. Bartram, B. Hertenstein, 1993, Leukemia.

Missense Variants in ATM in 26,101 Breast Cancer Cases and 29,842 Controls

M. Beckmann, P. Fasching, A. Ashworth, 2010, Cancer Epidemiology, Biomarkers & Prevention.

sense Variants in ATM in 26 , 101 Breast Cancer B & P es and 29 , 842 Controls

Janet, Arif, Meindl, 2010 .

Glycogenosis type Ib complicated by severe granulocytopenia resembling inherited neutropenia

C. Bartram, H. Bremer, H. Przyrembel, 1981, European Journal of Pediatrics.

Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant.

P. Bugert, K. Hemminki, A. Meindl, 2006, Carcinogenesis.

the Breast Cancer Association Consortium Five Polymorphisms and Breast Cancer Risk : Results from Updated

M. Beckmann, P. Fasching, N. Camp, 2009 .

Size and Composition of T-Cell Receptor δ (TCRD) Junctional Sequences Are Not Predictive of the Sensitivity of Clonospecific Oligonucleotides Designed for Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia

C. Bartram, T. Seriu, D. Erz, 2003, International journal of hematology.

factor AKAP13 with familial breast cancer

K. Hemminki, A. Meindl, B. Burwinkel, 2005 .

Chromosomal aberrations in sporadic pituitary tumors

A. Jauch, B. Harding, D. Ellison, 2001, International journal of cancer.

Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells.

Carl W. Miller, H Phillip Koeffler, M. D. Den Boer, 2009, Leukemia research.

CD10- pre-B acute lymphoblastic leukemia (ALL) is a distinct high-risk subgroup of adult ALL associated with a high frequency of MLL aberrations: results of the German Multicenter Trials for Adult ALL (GMALL).

E. Thiel, C. Bartram, C. Schoch, 2005, Blood.

Association of NCOA3 Polymorphisms with Breast Cancer Risk

Barbara Burwinkel, Peter Bugert, Asta Försti, 2005, Clinical Cancer Research.

The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study

A. Cox, D. Easton, P. Bugert, 2008, Breast Cancer Research and Treatment.

11q13 is a susceptibility locus for hormone receptor positive breast cancer

Jaana M. Hartikainen, S. Cross, R. Schulz-Wendtland, 2012, Human mutation.

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

M. Nöthen, R. Eeles, Z. Kote-Jarai, 2018, Nature Communications.

Large BRCA1 gene deletions are found in 3% of German high‐risk breast cancer families

C. Bartram, R. Klaes, B. Janssen, 2004, Human mutation.

Molecular evidence of minimal residual disease after treatment for leukaemia and lymphoma: an updated meeting report and review.

J. V. van Dongen, C. Bartram, J. Goldman, 1993, Leukemia.

MYEOV: A candidate gene for DNA amplification events occurring centromeric to CCND1 in breast cancer

E. Schuuring, C. Bartram, C. Theillet, 2002, International journal of cancer.

Breast cancer risk in BRCA1/2 mutation carriers and noncarriers under prospective intensified surveillance

D. Horn, T. Fehm, U. Bick, 2020, International journal of cancer.

The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A

Thomas W. Mühleisen, T. Mühleisen, M. Nöthen, 2015, Scientific Reports.

The 9 p 21 . 3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN 2 A

Thomas W. Mühleisen, T. Mühleisen, M. Nöthen, 2015 .

Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia

Daniel Sinnett, Csaba Szalai, Jasmine Healy, 2011, Haematologica.

Nuclear receptor coregulator SNP discovery and impact on breast cancer risk

Nina Ditsch, Steffi Oesterreich, Dieter Niederacher, 2009, BMC Cancer.

Variable number of tandem repeats polymorphism in the SMYD3 promoter region and the risk of familial breast cancer

P. Bugert, K. Hemminki, A. Meindl, 2006, International journal of cancer.

Medium-Chain Acyl-CoA Dehydrogenase Deficiency: Evaluation of Genotype-Phenotype Correlation in Patients Detected by Newborn Screening.

C. Bartram, G. Hoffmann, M. Lindner, 2015, JIMD reports.

Nonisotopic in situ hybridization for mapping oncogenic sequences.

O. Haas, C. Bartram, P. Ambros, 1987, Haematology and blood transfusion.

Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site

A. Ullrich, A. Schulz, C. Bartram, 1997, Oncogene.

Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer

A. Meindl, R. Schmutzler, C. Sutter, 2011, Human mutation.

Genetic variants within miR-126 and miR-335 are not associated with breast cancer risk

A. Schneeweiss, H. Brenner, P. Bugert, 2011, Breast Cancer Research and Treatment.

Low‐risk variants FGFR2, TNRC9 and LSP1 in German familial breast cancer patients

T. Meitinger, T. Illig, K. Hemminki, 2010, International journal of cancer.

Identification of a DMBT1 polymorphism associated with increased breast cancer risk and decreased promoter activity

P. Bugert, K. Hemminki, A. Meindl, 2010, Human mutation.

Polymorphisms in the Janus kinase 2 (JAK)/signal transducer and activator of transcription (STAT) genes: putative association of the STAT gene region with familial breast cancer.

K. Hemminki, A. Meindl, R. Schmutzler, 2007, Endocrine-related cancer.

Genetic variation in the major mitotic checkpoint genes does not affect familial breast cancer risk

P. Bugert, K. Hemminki, A. Meindl, 2007, Breast Cancer Research and Treatment.

Polymerase chain reaction analysis of BCR-ABL sequences in adult Philadelphia chromosome-negative acute lymphoblastic leukemia patients.

C. Bartram, W. Ludwig, C. Fonatsch, 1992, Leukemia.

Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics

D. Hose, H. Goldschmidt, A. Jauch, 2005, Genes, chromosomes & cancer.

Retinoids induce sister-chromatid exchanges in human diploid fibroblasts.

C. Bartram, H. Rüdiger, P. von Wichert, 1978, Mutation research.

The genomic structure of the human UFO receptor.

A. Schulz, C. Bartram, J. Janssen, 1993, Oncogene.

Persistence of chronic myelocytic leukemia despite deletion of rearranged bcr/c-abl sequences in blast crisis

C. Bartram, G. Grosveld, A. de Klein, 1986, The Journal of experimental medicine.

Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14).

D. Hose, H. Goldschmidt, A. Jauch, 2011, Blood.

High incidence and intraclonal heterogeneity of chromosome 11 aberrations in patients with newly diagnosed multiple myeloma detected by multiprobe interphase FISH.

D. Hose, H. Goldschmidt, A. Jauch, 2005, Cancer genetics and cytogenetics.

Mutations of the E2F4 gene in hematological malignancies having microsatellite instability.

C. Bartram, H. Koeffler, N. Komatsu, 2000, Blood.

(GMALL) aberrations: results of the German Multicenter Trials for Adult ALL subgroup of adult ALL associated with a high frequency of MLL CD10- pre-B acute lymphoblastic leukemia (ALL) is a distinct high-risk

E. Thiel, C. Bartram, C. Schoch, 2013 .

Benzpyrene-Induced sister chromatid exchanges in lymphocytes of patients with lung cancer

C. Bartram, H. Rüdiger, A. Schönwald, 1977, Human Genetics.

Benzpyrene induces sister chromatid exchanges in cultured human lymphocytes

C. Bartram, H. Rüdiger, E. Passarge, 1976, Nature.

HUMAN FIBROBLAST INTERFERON DOES NOT INDUCE CHROMOSOMAL ABNORMALITIES

C. Bartram, A. Schmidt, W. Mortier, 1981, The Lancet.

A case–control study of childhood acute lymphoblastic leukaemia and polymorphisms in the TGF‐β and receptor genes

K. Hemminki, Rajiv Kumar, M. Schrappe, 2009, Pediatric blood & cancer.

Improved yields of long PCR products using gene 32 protein.

K. Schwarz, C. Bartram, T. Hansen-Hagge, 1990, Nucleic acids research.

Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23.

R. Hanson, C. Bartram, C. Fischer, 2002, Kidney international.

Control of MYEOV Protein Synthesis by Upstream Open Reading Frames*

C. Bartram, R. Blaschke, J. Janssen, 2006, Journal of Biological Chemistry.

ERADICATION BY ALPHA-INTERFERON OF ONE CLONE IN BICLONAL HAIRY CELL LEUKAEMIA

C. Bartram, F. Porzsolt, A. Raghavachar, 1986, The Lancet.

Mutations in ROGDI Cause Kohlschütter-Tönz Syndrome.

Zlatko Trajanoski, Stephan Pabinger, Christof von Kalle, 2012, American journal of human genetics.

New Definition of Treatment Response in Adult Acute Lymphoblastic Leukemia (ALL): Use of Molecular Markers for Minimal Residual Disease (MRD).

T. Lipp, E. Thiel, A. Ganser, 2009 .

Primary Pulmonary Hypertension in Children May Have a Different Genetic Background Than in Adults

C. Bartram, H. Katus, B. Janssen, 2004, Pediatric Research.

Primary pulmonary hypertension may be a heterogeneous disease with a second locus on chromosome 2q31.

C. Bartram, H. Katus, B. Janssen, 2003, Journal of the American College of Cardiology.

Genetic Variation in ABCC4 and CFTR and Acute Pancreatitis during Treatment of Pediatric Acute Lymphoblastic Leukemia

R. Houlston, A. Franke, M. Schrappe, 2021, Journal of clinical medicine.

Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF 2

C. Bartram, T. Burmeister, S. Schwartz, 2008 .

A novel putative tyrosine kinase receptor with oncogenic potential.

A. Schulz, C. Bartram, P. Ambros, 1991, Oncogene.

ELIMINATION BY INTERFERON-ALPHA OF MALIGNANT CLONE IN CHRONIC MYELOID LEUKAEMIA

C. Bartram, N. Niederle, B. Opalka, 1989, The Lancet.

Molecular genetic aspects of myelodysplastic syndromes.

C. Bartram, Claus R. Bartram, 1992, Hematology/oncology clinics of North America.

Incidence and clinical implications of acute hybrid leukemia in childhood.

E. Thiel, J. Harbott, C. Bartram, 1990, Haematology and blood transfusion.

Conversion of acute undifferentiated leukemia phenotypes: analysis of clonal development.

G. Gaedicke, C. Bartram, G. Heil, 1986, Leukemia research.

Subacute sclerosing panencephalitis in a brother and sister

J. Henke, C. Bartram, J. Treuner, 1982, European Journal of Pediatrics.

Reduced Intensity Delayed Intensification in Standard-Risk Patients Defined By Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: Results of an International Randomized Trial in 1164 Patients (Trial AIEOP-BFM ALL 2000)

M. Schrappe, C. Bartram, M. Valsecchi, 2016 .

Risk/MRD adapted GMALL trials in adult ALL.

C. Bartram, M. Kneba, D. Hoelzer, 2004, Annals of hematology.

The Strong Prognostic Effect of Concurrent Deletions of IKZF1 and PAX5, CDKN2A, CDKN2B or PAR1 in the Absence of ERG Deletions (IKZF1plus) in Pediatric Acute Lymphoblastic Leukemia Strongly Depends on Minimal Residual Disease Burden after Induction Treatment

R. Houlston, M. Yaspo, A. Teigler‐Schlegel, 2014 .

Microsatellite instability and other molecular abnormalities in childhood acute lymphoblastic leukaemia

C. Bartram, H. Koeffler, J. Slater, 1997, British journal of haematology.

Prospective Evaluation of MRD-Kinetics in 274 Children with High-Risk ALL Treated in Trial ALL-BFM 2000: Insights into Development of Resistance and Impact on Further Refinement of Treatment Stratification Strategies.

B. Schäfer, M. Schrappe, C. Bartram, 2007 .

Gain of 1q21 and distinct adverse cytogenetic abnormalities correlate with increased microcirculation in multiple myeloma

H. Kauczor, D. Hose, H. Goldschmidt, 2008, International journal of cancer.

Novel interaction partners of the TPR/MET tyrosine kinase

C. Bartram, C. Schaaf, T. Schmitt, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Activation of the mas oncogene during transfection of monoblastic cell line DNA.

C. Bartram, J. Janssen, A. C. Steenvoorden, 1988, Leukemia.

Monitoring of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia — Preliminary Data from a Prospective Study

M. Schrappe, C. Bartram, W. Ludwig, 1998 .

bcr rearrangement in Ph-negative CML.

C. Bartram, F. Carbonell, 1986, Cancer genetics and cytogenetics.

Molecular and Cellular Pathobiology 19 p 13 . 1 Is a Triple-Negative – Speci fi c Breast Cancer Susceptibility Locus

Xiaoqing, Daniel J. Park, Arif, 2012 .

Primary pulmonary hypertension is predominantly a hereditary disease.

W. Seeger, C. Bartram, B. Janssen, 2002, Chest.

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia

B. Schäfer, M. Schrappe, C. Bartram, 2008, Leukemia.

Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting

M. Schrappe, C. Bartram, G. Basso, 2007, Leukemia.

Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies.

C. Bartram, H. Koeffler, D. Park, 1995, Cancer research.

Brief Definitive Report

C. Bartram, J. Penninger, H. Scott, 2003 .

A Breast Cancer Risk Haplotype in the Caspase-8 Gene Neil

N. Camp, A. Cox, A. Meindl, 2009 .

Use of polymerase chain reactions to monitor minimal residual disease in acute lymphoblastic leukemia patients.

C. Bartram, A. Reiter, C. Bartram, 1991, Blood.

Very Early/Early Relapses of ALL Show Unexpected Changes of Clonal Markers and High Heterogeneity in Initial and Relapse Treatment Response: ALL-BFM 2000 and ALL-REZ BFM 96/2002 .

M. Schrappe, C. Bartram, C. Eckert, 2009 .

Molecular genetic aspects of myelodysplastic syndromes.

C. Bartram, 1996, Seminars in hematology (Print).

The c-abl oncogene in chronic myelogenous leukemia.

A. Hagemeijer, N. Heisterkamp, J. Groffen, 1987, Haematologica.

Philadelphia-positive chronic myelogenous leukemia with breakpoint 5′ of the breakpoint cluster region but within the bcr gene

C. Bartram, H. Schmidt, H. Waller, 1987, Blut.

Rearrangement of bcr and c-abl sequences in Ph-positive acute leukemias and Ph-negative CML--an update.

C. Bartram, 1987, Haematology and blood transfusion.

Incidence of ras gene mutations in neuroblastoma

C. Bartram, J. Lyons, K. Ballas, 1988, European Journal of Pediatrics.

Analyses of phenotype and genotype in acute lymphoblastic leukemias at first presentation and in relapse.

E. Thiel, C. Bartram, C. Bartram, 1987, Blood.

BCR-ABL rearrangements in acute lymphoblastic leukaemia

J. Ardern, C. Bartram, G. Lucas, 1991, The Lancet.

A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1

M. Nöthen, James Allan, M. Greaves, 2016, Leukemia.

Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission.

A. Schulz, A. Borkhardt, J. Harbott, 1994, Blood.

bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia

C. Bartram, 1985, The Journal of Experimental Medicine.

Rapid and reliable quantification of minimal residual disease in acute lymphoblastic leukemia using rearranged immunoglobulin and T-cell receptor loci by LightCycler technology.

C. Bartram, J. Janssen, C. Bartram, 2000, Cancer research.

Intratumoral genomic heterogeneity in advanced head and neck cancer detected by comparative genomic hybridization.

A. Jauch, K. Hörmann, C. Bartram, 2005, Advances in Oto-Rhino-Laryngology.

Discovery of over-expressed genes and genetic alterations in breast cancer cells using a combination of suppression subtractive hybridization, multiplex FISH and comparative genomic hybridization.

A. Jauch, D. Xie, C. Bartram, 2002, International journal of oncology.

Detection and clinical relevance of genetic abnormalities in pediatric acute lymphoblastic leukemia: a comparison between cytogenetic and polymerase chain reaction analyses.

T. Lion, J. Harbott, O. Haas, 1993, Leukemia.

Immunoglobulin and T-cell receptor gene rearrangements in Hodgkin's disease.

C. Bartram, A. Raghavachar, T. Binder, 1988 .

The rare ERBB2 variant Ile654Val is associated with an increased familial breast cancer risk

R. Schmutzler, B. Burwinkel, B. Wappenschmidt, 2004 .

Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history

A. Meindl, R. Schmutzler, M. Kiechle, 2018, BMC Cancer.

Novel constitutional t(2;12)(q21;q22) in a patient with t(9;22)-negative chronic myelocytic leukemia.

A. Krämer, C. Bartram, A. Ho, 2003, Cancer genetics and cytogenetics.

Technology Immunoglobulin and T-Cell Receptor Loci by LightCycler in Acute Lymphoblastic Leukemia Using Rearranged Rapid and Reliable Quantification of Minimal Residual Disease

C. Bartram, T. Flohr, M. Nakao, 2000 .