J. Ikeda

发表

The position end-set tree: a small automaton for word recognition in biological sequences

Christophe Lefèvre, Joh-E Ikeda, C. Lefèvre, 1993, Comput. Appl. Biosci..

Neuronal apoptosis inhibitory protein (NAIP) may enhance the survival of granulosa cells thus indirectly affecting oocyte survival

J. Ikeda, K. Tanemura, E. Sato, 1999, Molecular reproduction and development.

The structures of integration sites in transgenic rice.

J. Ikeda, M. Takano, K. Wakasa, 1997, The Plant journal : for cell and molecular biology.

Isolation and characterization of 21 novel expressed DNA sequences from the distal region of human chromosome 4p.

S. Hadano, J. Ikeda, K. Wakasa, 1994, Genomics.

Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking

Y. Itoyama, S. Hadano, J. Ikeda, 2010, PloS one.

Defective relocalization of ALS2/alsin missense mutants to Rac1‐induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation

S. Hadano, J. Ikeda, A. Otomo, 2011, FEBS letters.

Inhibition of Cyclin-Dependent Kinases Improves CA1 Neuronal Survival and Behavioral Performance after Global Ischemia in the Rat

David S. Park, D. Corbett, J. Ikeda, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Free Radical Biology and Medicine

S. Hadano, J. Ikeda, Kazunori Tanaka, 2012 .

Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus

G. Robertson, J. Doucet, J. Ikeda, 1997, Nature Medicine.

Bromocriptine methylate suppresses glial inflammation and moderates disease progression in a mouse model of amyotrophic lateral sclerosis

S. Hadano, J. Ikeda, Kazunori Tanaka, 2011, Experimental Neurology.

A dopamine receptor antagonist L-745,870 suppresses microglia activation in spinal cord and mitigates the progression in ALS model mice

Y. Itoyama, S. Hadano, J. Ikeda, 2008, Experimental Neurology.

Production of transgenic miniature pigs by pronuclear microinjection

J. Ikeda, H. Imai, Y. Shimatsu, 2001, Transgenic Research.

Physical Map and Cosmid Contig Encompassing a New Interstitial Deletion of the X-Linked Lymphoproliferative Syndrome Region

D. Schlessinger, Amy Bernard, D. Haber, 1996, European journal of human genetics : EJHG.

SMA genes: deleted and duplicated

J. Ikeda, A. MacKenzie, R. Korneluk, 1995, Nature Genetics.

Expression of cauliflower mosaic virus reverse transcriptase in yeast

J. Ikeda, H. Hirochika, H. Takatsuji, 1986, Nature.

Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice

S. Hadano, J. Ikeda, Y. Iwakura, 2010, Neuroscience Research.

The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3.

S. Hadano, J. Ikeda, Y. Ishida, 1998, DNA research : an international journal for rapid publication of reports on genes and genomes.

Identification of two distinct transcripts for the neuronal apoptosis inhibitory protein gene.

K. Yamamoto, Y. Gondo, S. Hadano, 1999, Biochemical and biophysical research communications.

Isolation of expressed sequences encoded by the human Xq terminal portion using microclone probes generated by laser microdissection.

S. Hadano, J. Ikeda, K. Wakasa, 1994, Genomics.

Laser microdissection of the fragile X region: identification of cosmid clones and of conserved sequences in this region.

J. Ikeda, M. Mattei, I. Biunno, 1991, Genomics.

Identification and characterization of novel members of the CREG family, putative secreted glycoproteins expressed specifically in brain.

J. Ikeda, A. Otomo, R. Kunita, 2002, Genomics.

A Dopamine D4 Receptor Antagonist Attenuates Ischemia-Induced Neuronal Cell Damage via Upregulation of Neuronal Apoptosis Inhibitory Protein

S. Hadano, J. Ikeda, Kazunori Tanaka, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Morphodynamics of ovarian follicles during oogenesis in mice

J. Ikeda, Y. Miyake, E. Sato, 2006, Microscopy research and technique.

Nucleotide sequence of the insertion sequence found in the T-DNA region of mutant Ti plasmid pTiA66 and distribution of its homologues in octopine Ti plasmid.

Y. Suzuki, J. Ikeda, Y. Machida, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Two 5q13 simple tandem repeat loci are in linkage disequilibrium with type 1 spinal muscular atrophy.

L. Surh, J. Ikeda, A. MacKenzie, 1994, Human molecular genetics.

Chromosome microdissection and microcloning

J. Ikeda, Y. Saitoh, 1997, Chromosome Research.

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.

S. Hersch, M. Hayden, B. Leavitt, 2002, Human molecular genetics.

The effect of aphidicolin on adenovirus DNA synthesis.

J. Ikeda, M. Horwitz, S. Horwitz, 1979, Nucleic acids research.

HFM1, the human homologue of yeast Mer3, encodes a putative DNA helicase expressed specifically in germ-line cells

J. Ikeda, Kazunori Tanaka, N. Miyamoto, 2006, DNA sequence : the journal of DNA sequencing and mapping.

Cyclin-dependent kinases as a therapeutic target for stroke.

J. Ikeda, Raouf Fetni, A. Hakim, 2000, Proceedings of the National Academy of Sciences of the United States of America.

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics.

Shuh Narumiya, Takeharu Nishimoto, Asako Otomo, 2003, Human molecular genetics.

Co-expression and inheritance of foreign genes in transformants obtained by direct DNA transformation of tobacco protoplasts

J. Ikeda, H. Uchimiya, H. Hirochika, 1986, Molecular and General Genetics MGG.

Characterization of DNA sequences constituting the terminal heterochromatin of the chicken Z chromosome

J. Ikeda, I. Solovei, T. Hori, 1996, Chromosome Research.

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

Y. Gondo, S. Hadano, J. Ikeda, 2000, Genomics.

Molecular characterization and cytological mapping of a non-repetitive DNA sequence region from the W chromosome of chicken and its use as a universal probe for sexing Carinatae birds

J. Ikeda, I. Solovei, Y. Saitoh, 1997, Chromosome Research.

Isolation of proteins involved in the replication of adenoviral DNA in vitro.

J. Hurwitz, J. Ikeda, K. Nagata, 1983, Cold Spring Harbor symposia on quantitative biology.

Trapping of mammalian promoters by Cre-lox site-specific recombination.

J. Ikeda, S. Fukushige, 1996, DNA research : an international journal for rapid publication of reports on genes and genomes.

Novel Nuclear Shuttle Proteins, HDBP1 and HDBP2, Bind to Neuronal Cell-specific cis-Regulatory Element in the Promoter for the Human Huntington's Disease Gene*

J. Ikeda, Kazunori Tanaka, N. Miyamoto, 2004, Journal of Biological Chemistry.

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

T. Crawford, P. Jong, L. Surh, 1995, Cell.

Adenovirus DNA replication in vitro: purification of the terminal protein in a functional form.

J. Hurwitz, J. Ikeda, T. Enomoto, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Replication of adenovirus DNA-protein complex with purified proteins.

J. Hurwitz, J. Ikeda, T. Enomoto, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Adenoviral protein-primed initiation of DNA chains in vitro.

J. Hurwitz, J. Ikeda, T. Enomoto, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Identification of the origin of double minutes in normal human cells by laser-based chromosome microdissection approach

J. Ikeda, K. Wakasa, R. Korneluk, 1995, Human Genetics.

Inhibition of myogenesis in transgenic mice expressing the human DMPK 3'-UTR.

J. Ikeda, R. Korneluk, F. Jirik, 2004, Human molecular genetics.

Identification and characterization of the miniature pig Huntington's disease gene homolog: evidence for conservation and polymorphism in the CAG triplet repeat.

Y. Gondo, S. Hadano, J. Ikeda, 2000, Genomics.

Linear plasmid DNAs of the plant pathogenic fungus Rhizoctonia solani with unique terminal structures

J. Ikeda, H. Hirochika, T. Hashiba, 2004, Molecular and General Genetics MGG.

Laser microdissection and single unique primer PCR allow generation of regional chromosome DNA clones from a single human chromosome.

I. Kanazawa, S. Hadano, J. Ikeda, 1991, Genomics.

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene

I. Kanazawa, Y. Gondo, S. Hadano, 2002, Human Genetics.

Neuronal apoptosis inhibitory protein is implicated in amyotrophic lateral sclerosis symptoms

J. Ikeda, Kazunori Tanaka, O. Kano, 2018, Scientific Reports.

A multicopy dinucleotide marker that maps close to the spinal muscular atrophy gene.

J. McPherson, J. Carpten, Z. Kote-Jarai, 1994, Genomics.

Molecular and cellular function of ALS2/alsin: Implication of membrane dynamics in neuronal development and degeneration

Asako Otomo, S. Hadano, J. Ikeda, 2007, Neurochemistry International.

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

S. Scherer, Robert H. Brown, M. Hayden, 2001, Nature Genetics.

Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2.

S. Scherer, M. Hayden, G. Rouleau, 2001, Genomics.

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

S. Scherer, Robert H. Brown, M. Hayden, 2001, Nature Genetics.

Characterization of myotonic dystrophy kinase (DMK) protein in human and rodent muscle and central nervous tissue.

M. Somerville, W. Staines, J. Ikeda, 1995, Human molecular genetics.

Studies on DNA markers (D4S10 and D4S43/S127) genetically linked to Huntington's disease in Japanese families

I. Kanazawa, J. Gusella, J. Ikeda, 1990, Human Genetics.

Site‐specific deletion in cauliflower mosaic virus DNA: possible involvement of RNA splicing and reverse transcription

J. Ikeda, H. Hirochika, H. Takatsuji, 1985, EMBO Journal.

Role of DNA gyrase in phiX replicative-form replication in vitro.

J. Hurwitz, J. Ikeda, S. Schlagman, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

Y. Gondo, J. Ikeda, Y. Yanagisawa, 1998, Genomics.

Functional human NAIP promoter transcription regulatory elements for the NAIP and PsiNAIP genes.

S. Hadano, J. Ikeda, Y. Yanagisawa, 2002, Biochimica et biophysica acta.

Sequence of a 131-kb region of 5q13.1 containing the spinal muscular atrophy candidate genes SMN and NAIP.

J. Ikeda, A. MacKenzie, S. Baird, 1998, Genomics.

A linkage study with DNA markers (D4S95, D4S115, and D4S111) in Japanese Huntington disease families

Masahiko Watanabe, I. Kanazawa, J. Gusella, 1993, Japanese Journal of Human Genetics.

RNA polymerase in vegetative cells of Bacillus subtilis. II. New polypeptide factors, FI and FII, stimulating in vitro RNA synthesis directed by phage M2 DNA.

J. Ikeda, H. Saito, 1976, Journal of biochemistry.

Transcript map of the human chromosome 4p16.3 consisting of 627 cDNA clones derived from 1 Mb of the Huntington's disease locus.

K. Yamamoto, S. Hadano, J. Ikeda, 1996, DNA research : an international journal for rapid publication of reports on genes and genomes.

Homo-oligomerization of ALS2 through Its Unique Carboxyl-terminal Regions Is Essential for the ALS2-associated Rab5 Guanine Nucleotide Exchange Activity and Its Regulatory Function on Endosome Trafficking*

Asako Otomo, S. Hadano, J. Ikeda, 2004, Journal of Biological Chemistry.

Refined physical map of the spinal muscular atrophy gene (SMA) region at 5q13 based on YAC and cosmid contiguous arrays.

J. Carpten, J. Ikeda, R. Korneluk, 1995, Genomics.

Exclusion mapping of the hereditary dentatorubropallidoluysian atrophy gene from the Huntington's disease locus.

I. Kanazawa, J. Gusella, J. Ikeda, 1990, Journal of medical genetics.

Isolation and characterization of the protein coded by gene A of bacteriophage phiX174 DNA.

J. Hurwitz, J. Ikeda, A. Yudelevich, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of cyclophilin 40: highly conserved protein that directly associates with Hsp90.

J. Ikeda, H. Kondo, H. Anazawa, 1996, Biological & pharmaceutical bulletin.

Cloning and characterization of the nucleoredoxin gene that encodes a novel nuclear protein related to thioredoxin.

S. Minoguchi, T. Honjo, J. Ikeda, 1997, Genomics.

Investigation of Myotonic Dystrophy Kinase Isoform Translocation and Membrane Association*

J. Ikeda, K. Tamai, R. Korneluk, 1996, The Journal of Biological Chemistry.

Facteurs de transcription de gene de la choree de huntington

J. Ikeda, Kazunori Tanaka, 2002 .

Role of polymeric forms of the bacteriophage phi X174 coded gene A protein in phi XRFI DNA cleavage.

J. Hurwitz, J. Ikeda, N. Shimamoto, 1979, The Journal of biological chemistry.

Studies on the In Vitro Synthesis of ϕ X174 RFI DNA and Circular Single-stranded DNA

J. Hurwitz, J. Ikeda, S. Schlagman, 1978 .

The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis*

S. Hadano, J. Ikeda, A. Otomo, 2007, Journal of Biological Chemistry.

ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

S. Hadano, J. Ikeda, H. Osuga, 2007, Biochemical and biophysical research communications.

ALS2CL, the novel protein highly homologous to the carboxy‐terminal half of ALS2, binds to Rab5 and modulates endosome dynamics

S. Hadano, J. Ikeda, Y. Yanagisawa, 2004, FEBS letters.

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking.

Robert H. Brown, S. Hadano, J. Shefner, 2006, Human molecular genetics.

A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2-ARE pathway: therapeutic implications for ALS.

S. Hadano, J. Ikeda, Kazunori Tanaka, 2012, Free radical biology & medicine.

Single-nucleotide polymorphisms in uncoding regions of ALS2 gene of Japanese patients with autosomal-recessive amyotrophic lateral sclerosis

Koji Abe, Isao Nagano, Yasuhiro Manabe, 2003, Neurological research.

A yeast artificial chromosome-based physical map of the juvenile amyotrophic lateral sclerosis (ALS2) critical region on human chromosome 2q33-q34.

S. Scherer, M. Hayden, R. Brinkman, 1999, Genomics.

ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth.

S. Hadano, J. Ikeda, H. Osuga, 2008, Biochemical and biophysical research communications.

A recombination event occurring within two complex 5q13.1 microsatellite repeat polymorphisms suggests a telomeric mapping of spinal muscular atrophy

L. Surh, J. Ikeda, A. MacKenzie, 1995, Human Genetics.

Purification and functional analyses of ALS2 and its homologue.

S. Hadano, J. Ikeda, 2005, Methods in enzymology.

A novel function of N-linked glycoproteins, alpha-2-HS-glycoprotein and hemopexin: Implications for small molecule compound-mediated neuroprotection

S. Hadano, J. Ikeda, Kazunori Tanaka, 2017, PloS one.

Generation of high-density DNA markers from yeast artificial chromosome DNA by single unique primer-polymerase chain reaction.

H. Lehrach, S. Hadano, J. Ikeda, 1993, Genetic analysis, techniques and applications.

A Novel Acylaminoimidazole Derivative, WN1316, Alleviates Disease Progression via Suppression of Glial Inflammation in ALS Mouse Model

S. Inoue, J. Ikeda, Kazunori Tanaka, 2014, PloS one.

Genomic organization of the human caspase-9 gene on Chromosome 1p36.1-p36.3

M. Hayden, S. Hadano, J. Ikeda, 1999, Mammalian Genome.

A novel tandem repeat sequence located on human chromosome 4p: isolation and characterization.

S. Hadano, C. Lefèvre, J. Ikeda, 1997, Genomics.

Elongation of primed DNA templates by eukaryotic DNA polymerases.

J. Hurwitz, J. Ikeda, M. Horwitz, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Replication of phiX174 DNA: in vitro synthesis of phiX RFI DNA and circular, single-stranded DNA.

J. Hurwitz, J. Ikeda, R. Vicuña, 1979, Cold Spring Harbor symposia on quantitative biology.

Neuronal apoptosis inhibitory protein is implicated in amyotrophic lateral sclerosis symptoms

Yasuo Iwasaki, J. Ikeda, Kazunori Tanaka, 2018, Scientific Reports.

Free Radical Biology and Medicine

S. Hadano, J. Ikeda, Kazunori Tanaka, 2012 .

A dopamine receptor antagonist L-745,870 suppresses microglia activation in spinal cord and mitigates the progression in ALS model mice

Y. Itoyama, S. Hadano, J. Ikeda, 2008, Experimental Neurology.

Selective inhibition of phiX RFII compared with fd RFII DNA synthesis in vitro. II. Resolution of discrimination reaction into multiple steps.

J. Hurwitz, J. Ikeda, R. Vicuña, 1977, The Journal of biological chemistry.

The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene.

J. Ikeda, R. Korneluk, H. Anazawa, 1996, Genomics.