C. Fahrni

发表

Tuning the photoinduced electron-transfer thermodynamics in 1,3,5-triaryl-2-pyrazoline fluorophores: X-ray structures, photophysical characterization, computational analysis, and in vivo evaluation.

C. Fahrni, Liuchun Yang, D. VanDerveer, 2003, Journal of the American Chemical Society.

Metal Ion-Responsive Fluorescent Probes for Two-Photon Excitation Microscopy.

C. Fahrni, S. Sumalekshmy, 2011, Chemistry of materials : a publication of the American Chemical Society.

The chemical cell biology of zinc: structure and intracellular fluorescence of a zinc-quinolinesulfonamide complex

C. Fahrni, T. O’Halloran, D. Suhy, 1999, JBIC Journal of Biological Inorganic Chemistry.

Ratiometric two-photon microscopy reveals attomolar copper buffering in normal and Menkes mutant cells

C. Fahrni, V. Faundez, Gabriele Meloni, 2019, Proceedings of the National Academy of Sciences.

MicroXRF tomographic visualization of zinc and iron in the zebrafish embryo at the onset of the hatching period.

C. Fahrni, C. Shin, S. Vogt, 2016, Metallomics : integrated biometal science.

Glutathione limits aquacopper(I) to sub-femtomolar concentrations through cooperative assembly of a tetranuclear cluster

C. Fahrni, M. Morgan, Lily Anh H Nguyen, 2017, The Journal of Biological Chemistry.

The Effect of Ligand Constraints on the Metal-to-Ligand Charge-Tranfer Relaxation Dynamics of Copper(I)−Phenanthroline Complexes: A Comparative Study by Femtosecond Time-Resolved Spectroscopy

C. Fahrni, C. Burda, A. Samia, 2004 .

A Fluorogenic Probe for the Copper(I)-Catalyzed Azide−Alkyne Ligation Reaction: Modulation of the Fluorescence Emission via 3(n,π*)−1(π,π*) Inversion

C. Fahrni, Zhen Zhou, 2004 .

Excited-State Intramolecular Proton Transfer in 2-(2'-Tosylaminophenyl)benzimidazole

C. Fahrni, D. VanDerveer, M. Henary, 2002 .

Subcellular redistribution and mitotic inheritance of transition metals in proliferating mouse fibroblast cells.

B. Lai, C. Fahrni, Reagan L. McRae, 2013, Metallomics : integrated biometal science.

Zinc homeostasis and zinc signaling in white matter development and injury

C. Fahrni, P. Rosenberg, C. Elitt, 2019, Neuroscience Letters.

Chromis-1, a Ratiometric Fluorescent Probe Optimized for Two-Photon Microscopy Reveals Dynamic Changes in Labile Zn(II) in Differentiating Oligodendrocytes.

J. Perry, C. Fahrni, P. Rosenberg, 2018, ACS sensors.

Fluorogenic Strain-Promoted Alkyne-Diazo Cycloadditions.

C. Fahrni, G. Boons, F. Friscourt, 2015, Chemistry.

Excited State Intramolecular Proton Transfer and Metal Ion Complexation of 2-(2‘-Hydroxyphenyl)benzazoles in Aqueous Solution

C. Fahrni, M. Henary, 2002 .

Copper redistribution in Atox1-deficient mouse fibroblast cells

B. Lai, C. Fahrni, Reagan L. McRae, 2009, JBIC Journal of Biological Inorganic Chemistry.

A fluorogenic probe for the copper(I)-catalyzed azide-alkyne ligation reaction: modulation of the fluorescence emission via 3(n,pi)-1(pi,pi) inversion.

C. Fahrni, Zhen Zhou, 2004, Journal of the American Chemical Society.

Molecular recognition based on low-affinity polyvalent interactions: selective binding of a carboxylated polymer to fibronectin fibrils of live fibroblast cells.

C. Fahrni, U. Bunz, Ronnie L. Phillips, 2008, Journal of the American Chemical Society.

Structure and Properties of Transition‐Metal Complexes with Chiral C2‐symmetric binucleating ligands

C. Fahrni, M. Neuburger, A. Pfaltz, 1998 .

Allylic oxidation catalyzed by chiral dinuclear copper complexes

C. Fahrni, 1998 .

Session lectures

I. Issaeva, C. Fahrni, S. Vogt, 2014, JBIC Journal of Biological Inorganic Chemistry.

Copper(I) Fluorescent Probes

C. Fahrni, M. Morgan, Pritha Bagchi, 2013 .

Electronically tuned 1,3,5-triarylpyrazolines as Cu(I)-selective fluorescent probes.

C. Fahrni, M. Morgan, M. Verma, 2010, Organic & biomolecular chemistry.

Synthesis of Chiral C2‐Symmetric Binucleating Ligands

C. Fahrni, A. Pfaltz, 1998 .

In situ imaging of metals in cells and tissues.

Pritha Bagchi, C. Fahrni, S. Sumalekshmy, 2009, Chemical reviews.

X-ray structures, photophysical characterization, and computational analysis of geometrically constrained copper(I)--phenanthroline complexes.

C. Fahrni, D. VanDerveer, C. Sherrill, 2003, Inorganic chemistry.

Probing Biological Trace Metals with Fluorescent Indicators

C. Fahrni, Daisy Bourassa, R. Dikdan, 2017 .

High-contrast Cu(I)-selective fluorescent probes based on synergistic electronic and conformational switching.

C. Fahrni, S. Mandal, K. Hardcastle, 2011, Chemical science.

Kinetically controlled photoinduced electron transfer switching in Cu(I)-responsive fluorescent probes.

J. Perry, C. Fahrni, Nisan Siegel, 2010, Journal of the American Chemical Society.

5-aza-semicorrins: A new class of bidentate nitrogen ligands for enantioselective catalysis

C. Fahrni, A. Pfaltz, G. Umbricht, 1992 .

Metal ion chaperone function of the soluble Cu(I) receptor Atx1.

Shin Lin, C. Fahrni, T. O’Halloran, 1997, Science.

A fluorogenic probe for the catalyst-free detection of azide-tagged molecules.

C. Fahrni, G. Boons, F. Friscourt, 2012, Journal of the American Chemical Society.

Fluorescence sensing based on cation-induced conformational switching: copper-selective modulation of the photoinduced intramolecular charge transfer of a donor–acceptor biphenyl fluorophore

C. Fahrni, John Cody, 2004 .

Differential tuning of the electron transfer parameters in 1,3,5-triarylpyrazolines: a rational design approach for optimizing the contrast ratio of fluorescent probes.

C. Fahrni, Liuchun Yang, S. Mandal, 2008, Journal of the American Chemical Society.

Zinc(II)-selective ratiometric fluorescent sensors based on inhibition of excited-state intramolecular proton transfer.

C. Fahrni, M. Henary, Christoph J Fahrni, 2004, Chemistry.

Excited-state intramolecular proton transfer in 2-(2'-arylsulfonamidophenyl)benzimidazole derivatives: the effect of donor and acceptor substituents.

C. Fahrni, M. Henary, S. Mandal, 2007, The Journal of organic chemistry.

Excited state intramolecular proton transfer in 2-(2'-arylsulfonamidophenyl)benzimidazole derivatives: insights into the origin of donor substituent-induced emission energy shifts.

C. Fahrni, J. Brédas, K. Schmidt, 2007, The journal of physical chemistry. A.

Aqueous Coordination Chemistry of Quinoline-Based Fluorescence Probes for the Biological Chemistry of Zinc

C. Fahrni, T. O’Halloran, 1999 .

Design of Cation‐Selective Synthetic Fluorescent Indicators

C. Fahrni, 2011 .

Fluorescent Probes for Two-Photon Excitation Microscopy

C. Fahrni, 2009 .

Imaging of the intracellular topography of copper with a fluorescent sensor and by synchrotron x-ray fluorescence microscopy.

B. Lai, C. Fahrni, Liuchun Yang, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Probing Ternary Complex Equilibria of Crown Ether Ligands by Time-Resolved Fluorescence Spectroscopy

C. Fahrni, S. Sumalekshmy, M. Morgan, 2014, The journal of physical chemistry. B.

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Philippe P Roux, L. Gaboury, C. Fahrni, 2020, Nature Communications.

Biological applications of X-ray fluorescence microscopy: exploring the subcellular topography and speciation of transition metals.

C. Fahrni, Christoph J Fahrni, 2007, Current opinion in chemical biology.

High-affinity Cu(I) chelator PSP-2 as potential anti-angiogenic agent

B. Lai, C. Fahrni, J. Buschmann, 2019, Scientific Reports.

Synthetic fluorescent probes for monovalent copper.

C. Fahrni, 2013, Current opinion in chemical biology.

Stabilization of Aliphatic Phosphines by Auxiliary Phosphine Sulfides Offers Zeptomolar Affinity and Unprecedented Selectivity for Probing Biological CuI.

C. Forest, C. Fahrni, Ronghu Wu, 2018, Angewandte Chemie.

3D imaging of transition metals in the zebrafish embryo by X-ray fluorescence microtomography.

Stefan Vogt, Sophie-Charlotte Gleber, Fabian Will, 2014, Metallomics : integrated biometal science.

In situ Imaging of Metals in Cells and Tissues

Pritha Bagchi, C. Fahrni, S. Sumalekshmy, 2010 .

Predicting the photoinduced electron transfer thermodynamics in polyfluorinated 1,3,5-triarylpyrazolines based on multiple linear free energy relationships.

C. Fahrni, M. Verma, Aneese F. Chaudhry, 2009, Organic & biomolecular chemistry.

Trafficking mechanisms of P-type ATPase copper transporters.

C. Fahrni, V. Faundez, A. Vrailas-Mortimer, 2019, Current opinion in cell biology.

High-contrast fluorescence sensing of aqueous Cu(I) with triarylpyrazoline probes: dissecting the roles of ligand donor strength and excited state proton transfer.

C. Fahrni, M. Morgan, Pritha Bagchi, 2013, Dalton transactions.

Designed to dissolve: suppression of colloidal aggregation of Cu(I)-selective fluorescent probes in aqueous buffer and in-gel detection of a metallochaperone.

C. Fahrni, M. Morgan, Pritha Bagchi, 2011, Journal of the American Chemical Society.

Design of emission ratiometric metal-ion sensors with enhanced two-photon cross section and brightness.

Nisan Siegel, Jean-Luc Brédas, Joseph W Perry, 2007, Journal of the American Chemical Society.

Rational design of a water-soluble, lipid-compatible fluorescent probe for Cu(i) with sub-part-per-trillion sensitivity

C. Fahrni, M. Morgan, A. McCallum, 2015, Chemical science.

Robust affinity standards for Cu(I) biochemistry.

C. Fahrni, J. Bacsa, M. Morgan, 2013, Journal of the American Chemical Society.

Transmembrane Cu(i) P-type ATPase pumps are electrogenic uniporters.

C. Fahrni, Gabriele Meloni, M. Morgan, 2020, Dalton transactions.

Correlative microXRF and optical immunofluorescence microscopy of adherent cells labeled with ultrasmall gold particles.

B. Lai, C. Fahrni, S. Vogt, 2006, Journal of structural biology.

In Situ Imaging of Zinc with Synthetic Fluorescent Probes

C. Fahrni, Jiyao Yu, 2019, Zinc Signaling.

Signal Discrimination Between Fluorescent Proteins in Live Cells by Long-wavelength Optical Modulation.

C. Fahrni, R. Dickson, Amy E. Jablonski, 2012, The journal of physical chemistry letters.

9-Aryl-9-xanthenols: a convenient platform for the design of fluorimetric and colorimetric pH indicators.

C. Fahrni, V. Popik, Emmanuel E. Nekongo, 2012, Organic & biomolecular chemistry.

Optically Modulated and Optically Activated Delayed Fluorescent Proteins through Dark State Engineering.

C. Fahrni, R. Dickson, S. Hill, 2021, The journal of physical chemistry. B.

Stabilization of Aliphatic Phosphines by Auxiliary Phosphine Sulfides Offers Zeptomolar Affinity and Unprecedented Selectivity for Probing Biological CuI.

C. Forest, C. Fahrni, Ronghu Wu, 2018, Angewandte Chemie.

High-Affinity Cu(I)-Chelator with Potential Anti-Tumorigenic Action—A Proof-of-Principle Experimental Study of Human H460 Tumors in the CAM Assay

C. Fahrni, C. Waschkies, K. Spanaus, 2022, Cancers.

Optically Modulated Photoswitchable Fluorescent Proteins Yield Improved Biological Imaging Sensitivity.

I. Issaeva, C. Fahrni, R. Dickson, 2015, Journal of the American Chemical Society.

Anomalous photophysics of bis(hydroxystyryl)benzenes: a twist on the para/meta dichotomy.

C. Fahrni, K. Solntsev, U. Bunz, 2008, Organic letters.

Developmental regulation of zinc homeostasis in differentiating oligodendrocytes

C. Fahrni, P. Rosenberg, Jianlin Wang, 2023, bioRxiv.

Conformationally Preorganized High-Affinity Ligands for Copper Biology with Hinged and Rigid Thiophene Backbones.

C. Fahrni, J. Bacsa, Jiyao Yu, 2023, Inorganic chemistry.

Preorganized PSP Ligands Yield Monomeric Cu(I) Complexes with Subzeptomolar Cu(I) Dissociation Constants.

C. Fahrni, M. Morgan, Farzaneh Saeedifard, 2019, Inorganic chemistry.