K. Kirsch

发表

Mader: a novel nuclear protein over expressed in human melanomas.

K. Kirsch, Y. Korradi, J. Johnson, 1996, Oncogene.

Recombinant Lysyl Oxidase Propeptide Protein Inhibits Growth and Promotes Apoptosis of Pre-Existing Murine Breast Cancer Xenografts

M. Nugent, G. Sonenshein, K. Kirsch, 2012, PloS one.

mTORC1-Egr1-ATGL-Mediated Pathway the Evolutionarily Conserved Insulin Inhibits Lipolysis in Adipocytes via

Yuanyuan Wu, K. Kirsch, K. Kandror, 2014 .

Expression of a phosphorylated substrate domain of p130Cas promotes PyMT-induced c-Src-dependent murine breast cancer progression.

P. Toselli, Shi Yang, K. Kirsch, 2013, Carcinogenesis.

The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130Cas in Breast Cancer Cells*

G. Sonenshein, K. Kirsch, S. Vora, 2009, Journal of Biological Chemistry.

Genomic organization of the melanoma-associated glycoprotein MUC18: implications for the evolution of the immunoglobulin domains.

K. Kirsch, J. Johnson, C. Sers, 1993, Proceedings of the National Academy of Sciences of the United States of America.

A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-Crk signaling

H. Hanafusa, K. Kirsch, A. August, 2002, BMC Cell Biology.

Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II

R. Birge, K. Kirsch, J. Fajardo, 2001, Oncogene.

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

D. Burton, K. Kirsch, W. Schief, 2022, Immunity.

Regulation of p130(Cas)/BCAR1 expression in tamoxifen-sensitive and tamoxifen-resistant breast cancer cells by EGR1 and NAB2.

K. Kirsch, J. Kumbrink, 2012, Neoplasia.

Stabilization and productive positioning roles of the C2 domain of PTEN tumor suppressor.

H. Hanafusa, K. Kirsch, N. Pavletich, 2000, Cancer research.

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region.

H. Hanafusa, K. Kirsch, M. Georgescu, 1999, Proceedings of the National Academy of Sciences of the United States of America.

p130Cas acts as survival factor during PMA-induced apoptosis in HL-60 promyelocytic leukemia cells.

K. Kirsch, J. Kumbrink, 2013, The international journal of biochemistry & cell biology.

EGR1, EGR2, and EGR3 activate the expression of their coregulator NAB2 establishing a negative feedback loop in cells of neuroectodermal and epithelial origin

K. Kirsch, Judith P. Johnson, J. Kumbrink, 2010, Journal of cellular biochemistry.

The Ras Signaling Inhibitor LOX-PP Interacts with Hsp70 and c-Raf To Reduce Erk Activation and Transformed Phenotype of Breast Cancer Cells

G. Sonenshein, K. Kirsch, J. Myllyharju, 2011, Molecular and Cellular Biology.

Blimp1 Activation by AP-1 in Human Lung Cancer Cells Promotes a Migratory Phenotype and Is Inhibited by the Lysyl Oxidase Propeptide

G. Sonenshein, K. Kirsch, P. Trackman, 2012, PloS one.

Driven Breast Cancer − Propeptide Reverses the Invasive Phenotype of Her-2 / neu The Tumor Suppressor Activity of the Lysyl Oxidase

G. Sonenshein, K. Kirsch, S. Jeay, 2007 .

Biological Effects of c-Mer Receptor Tyrosine Kinase in Hematopoietic Cells Depend on the Grb2 Binding Site in the Receptor and Activation of NF-κB

H. Hanafusa, K. Kirsch, M. Georgescu, 1999, Molecular and Cellular Biology.

Expression of a phosphorylated p130Cas substrate domain attenuates the phosphatidylinositol 3‐kinase/Akt survival pathway in tamoxifen resistant breast cancer cells

R. Nicholson, K. Kirsch, Shefali Soni, 2009, Journal of cellular biochemistry.

Direct Binding of p130Cas to the Guanine Nucleotide Exchange Factor C3G*

H. Hanafusa, K. Kirsch, M. Georgescu, 1998, The Journal of Biological Chemistry.

Targeting Cas Family Proteins as a Novel Treatment for Breast Cancer

K. Kirsch, J. Kumbrink, 2011 .

A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer.

J. Palmer, G. Sonenshein, K. Kirsch, 2009, Cancer research.

The Lysyl Oxidase Propeptide Interacts with the Receptor-Type Protein Tyrosine Phosphatase Kappa and Inhibits β-Catenin Transcriptional Activity in Lung Cancer Cells

G. Sonenshein, K. Kirsch, P. Trackman, 2011, Molecular and Cellular Biology.

Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3)*

S. Knapp, P. Simister, S. Feller, 2015, The Journal of Biological Chemistry.

Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells.

M. Wu, G. Sonenshein, K. Kirsch, 2007, Cancer research.

Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2

G. Sonenshein, K. Kirsch, Xiaobo Wang, 2007, Nature Cell Biology.

Repression of BCL 2 by the Tumor Suppressor Activity of the Lysyl Oxidase Propeptide Inhibits Transformed Phenotype of Lung and Pancreatic Cancer Cells

M. Wu, G. Sonenshein, K. Kirsch, 2007 .

A polymorphism in the lysyl oxidase propeptide domain accelerates carcinogen-induced cancer

Shi Yang, G. Sonenshein, K. Kirsch, 2018, Carcinogenesis.

A truncated phosphorylated p130Cas substrate domain is sufficient to drive breast cancer growth and metastasis formation in vivo

K. Kirsch, Shefali Soni, A. Cueva, 2016, Tumor Biology.

CMS: an adapter molecule involved in cytoskeletal rearrangements.

H. Hanafusa, K. Kirsch, M. Georgescu, 1999, Proceedings of the National Academy of Sciences of the United States of America.

The Adapter Type Protein CMS/CD2AP Binds to the Proto-oncogenic Protein c-Cbl through a Tyrosine Phosphorylation-regulated Src Homology 3 Domain Interaction*

R. Birge, H. Hanafusa, K. Kirsch, 2001, The Journal of Biological Chemistry.

Structure and function analysis of the CMS/CIN85 protein family identifies actin-bundling properties and heterotypic-complex formation

P. Toselli, K. Kirsch, Shefali Soni, 2007, Journal of Cell Science.

A B Cell Receptor with Two Igα Cytoplasmic Domains Supports Development of Mature But Anergic B Cells

K. Rajewsky, M. Nussenzweig, K. Kirsch, 2004, The Journal of experimental medicine.

The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.

G. Sonenshein, K. Kirsch, S. Jeay, 2007, Cancer research.

Lysyl Oxidase Pro-peptide Inhibits Prostate Cancer Cell Growth by Mechanisms that Target FGF-2-Cell Binding and Signaling

M. Nugent, G. Sonenshein, K. Kirsch, 2009, Oncogene.

UXT Is a LOX‐PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells

G. Sonenshein, K. Kirsch, P. Trackman, 2017, Journal of cellular biochemistry.

One‐step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice

K. Kirsch, W. Schief, U. Nair, 2018, The EMBO journal.

Insulin Inhibits Lipolysis in Adipocytes via the Evolutionarily Conserved mTORC1-Egr1-ATGL-Mediated Pathway

Yuanyuan Wu, K. Kirsch, K. Kandror, 2013, Molecular and Cellular Biology.

Characterization of recombinant lysyl oxidase propeptide.

G. Sonenshein, K. Kirsch, Ying Guo, 2010, Biochemistry.

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors

K. Kirsch, W. Schief, Yumiko Adachi, 2020, The EMBO journal.

Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.

G. Chuang, K. Kirsch, Reda Rawi, 2021, Immunity.

Cysteine-rich protein 2 alters p130Cas localization and inhibits vascular smooth muscle cell migration.

K. Kirsch, Y. Chuang, M. Layne, 2013, Cardiovascular research.

Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin‐induced apoptosis

G. Sonenshein, K. Kirsch, P. Trackman, 2010, Journal of cellular biochemistry.

Inhibition of CIN85-Mediated Invasion by a Novel SH3 Domain Binding Motif in the Lysyl Oxidase Propeptide

P. Simister, S. Feller, G. Sonenshein, 2013, PloS one.

Melanoma-Associated Adhesion Molecule MUC18/MCAM (CD146) and Transcriptional Regulator Mader in Normal Human CNS

H. Hampel, M. Schwarz, M. Ackenheil, 1998, Neuroimmunomodulation.

The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice

Ying Chen, K. Kirsch, N. Shrestha, 2023, International journal of molecular sciences.

Expression of a phosphorylated substrate domain of p130Cas promotes PyMT-induced c-Src-dependent murine breast cancer progression.

P. Toselli, Shi Yang, K. Kirsch, 2013, Carcinogenesis.

UXT Is a LOX‐PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells

G. Sonenshein, K. Kirsch, P. Trackman, 2017, Journal of Cellular Biochemistry.