Sherry L. Niessen

发表

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

D. Nomura, J. Long, Sherry L. Niessen, 2010, Cell.

A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue

F. Piano, K. Gunsalus, K. Oegema, 2011, Cell.

A streamlined platform for high-content functional proteomics of primary human specimens

Nasreen S Jessani, S. Jeffrey, W. Han, 2005, Nature Methods.

Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes

A. Russell, J. Chang, D. Nomura, 2013, Nature chemical biology.

Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling.

Sherry L. Niessen, Heather S Hoover, B. Cravatt, 2008, Bioorganic & medicinal chemistry letters.

The Proteome of Mouse Brain Microvessel Membranes and Basal Lamina

Andrew Baird, J. Yates, B. Torbett, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Activity-based Protein Profiling Implicates Urokinase Activation as a Key Step in Human Fibrosarcoma Intravasation*

Sherry L. Niessen, B. Cravatt, J. Quigley, 2006, Journal of Biological Chemistry.

TRB 3 Links the E 3 Ubiquitin Ligase COP 1 to Lipid Metabolism

J. Yates, R. Evans, Sherry L. Niessen, 2009 .

Dim1p Is Required for Efficient Splicing and Export of mRNA Encoding Lid1p, a Component of the Fission Yeast Anaphase-Promoting Complex

J. Yates, K. Gould, Sherry L. Niessen, 2005, Eukaryotic Cell.

Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids

G. Siuzdak, J. Long, Sherry L. Niessen, 2011, Nature chemical biology.

Reversible lysine-targeted probes reveal residence time-based kinase selectivity

A. Burlingame, J. Taunton, J. Lapek, 2022, Nature Chemical Biology.

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1

L. Lum, K. Gajiwala, Sherry L. Niessen, 2020, The Journal of biological chemistry.

Major Cys protease activities are not essential for senescence in individually darkened Arabidopsis leaves

A. Millar, Sherry L. Niessen, T. Shindo, 2017, BMC Plant Biology.

Proteomic profiling of metalloprotease activities with cocktails of active-site probes

Sherry L. Niessen, Heather S Hoover, B. Cravatt, 2006, Nature chemical biology.

Chemoproteomic Discovery of AADACL1 as a Novel Regulator of Human Platelet Activation

Justin L. Black, Sherry L. Niessen, B. Cravatt, 2014 .

Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation.

Justin L. Black, J. Chang, Sherry L. Niessen, 2013, Chemistry & biology.

Proteasome Activity Imaging and Profiling Characterizes Bacterial Effector Syringolin A1[W]

Sherry L. Niessen, M. Kaiser, H. Overkleeft, 2010, Plant Physiology.

Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly.

K. Oegema, A. Desai, Huilin Zhou, 2013, Developmental cell.

PRMT5 modulates the metabolic response to fasting signals

J. Yates, E. Guccione, Sherry L. Niessen, 2013, Proceedings of the National Academy of Sciences.

Reversible lysine-targeted probes reveal residence time-based kinase selectivity

A. Burlingame, J. Taunton, J. Lapek, 2022, Nature Chemical Biology.

Nucleic Acid– Binding Proteins

Sherry L. Niessen, B. Cravatt, T. Land, 2009 .

An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling.

A. Saghatelian, Sherry L. Niessen, B. Cravatt, 2006, Chemistry & biology.

Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival.

Melinda M. Mulvihill, Steven J Brown, J. Chang, 2015, ACS chemical biology.

Purification and Characterization of Proteins

Sherry L. Niessen, B. Cravatt, T. Land, 2009 .

Forward chemical genetic approach identifies new role for GAPDH in insulin signaling.

John R Yates, Fabio Piano, Young-Tae Chang, 2007, Nature chemical biology.

Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors

A. Desai, R. Gassmann, Sherry L. Niessen, 2015, Molecular biology of the cell.

1 Subclassification and Biochemical Analysis 1 of Plant Papain-like Cysteine Proteases displays 2 Subfamily-specific Characteristics 3 4

M. Bogyo, Sherry L. Niessen, K. Stüber, 2012 .

Protein–Ligand Interactions

Sherry L. Niessen, B. Cravatt, T. Land, 2009 .

Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor.

X. Mu, J. Bienkowska, Zhou Zhu, 2021, Cancer cell.

Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition.

Sherry L. Niessen, B. Cravatt, J. Berlin, 2012, Journal of the American Chemical Society.

Activity‐Based Probes for Monitoring Postproline Protease Activity

T. Tarragó, E. Giralt, Sherry L. Niessen, 2009, Chembiochem : a European journal of chemical biology.

Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome

S. Benkovic, Hong Zhao, Sherry L. Niessen, 2013, Proceedings of the National Academy of Sciences.

The CREB Coactivator TORC2 Functions as a Calcium- and cAMP-Sensitive Coincidence Detector

J. Yates, M. Conkright, Sherry L. Niessen, 2004, Cell.

Type I Signal Peptidase and Protein Secretion in Staphylococcus aureus

Sherry L. Niessen, F. Romesberg, Mark A. Schallenberger, 2012, Journal of bacteriology.

Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

Sherry L. Niessen, D. Cleveland, A. Holland, 2010, The Journal of cell biology.

Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.

Paolo Vicini, Deepak Dalvie, Chengyi Zhang, 2017, Journal of medicinal chemistry.

An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis.

Timothy L. Foley, Sherry L. Niessen, Heather S Hoover, 2009, ACS chemical biology.

Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer.

J. Lapek, Sherry L. Niessen, M. McTigue, 2021, Journal of medicinal chemistry.

Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors.

K. Gajiwala, Sherry L. Niessen, B. Cravatt, 2017, Cell chemical biology.

A roadmap to evaluate the proteome-wide selectivity of covalent kinase inhibitors

Benjamin F. Cravatt, Theodore O. Johnson, Matthew M. Hayward, 2014, Nature chemical biology.

The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain

Daniel R. Beisner, T. Wiltshire, M. Cooke, 2013, The Journal of experimental medicine.

Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo.

John R Yates, Nadim Jessani, Nasreen S Jessani, 2004, Proceedings of the National Academy of Sciences of the United States of America.

TRB3 Links the E3 Ubiquitin Ligase COP1 to Lipid Metabolism

J. Yates, R. Evans, Sherry L. Niessen, 2006, Science.

Breast Cancer Cell Lines Grown In Vivo: What Goes in Isn’t Always the Same as What Comes Out

Nasreen S Jessani, Sherry L. Niessen, B. Cravatt, 2005, Cell cycle.

Subclassification and Biochemical Analysis of Plant Papain-Like Cysteine Proteases Displays Subfamily-Specific Characteristics1[C][W]

M. Bogyo, Sherry L. Niessen, K. Stüber, 2012, Plant Physiology.

Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula

J. Yates, P. Dorrestein, R. Reinhardt, 2011, Proceedings of the National Academy of Sciences.

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

Sherry L. Niessen, B. Cravatt, A. Adibekian, 2010, Proceedings of the National Academy of Sciences.

Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.

Deepak Dalvie, Michael Zientek, Rose Ann Ferre, 2016, Journal of medicinal chemistry.

Regulation of Tumor Necrosis Factor Receptor-1 and the Ikk-nf-␬b Pathway by Ldl Receptor–related Protein Explains the Antiinflammatory Activity of This Receptor Low-density Lipoprotein Receptor–related Protein (lrp-1) Functions in Endocytosis and in Cell Signaling Directly (by Binding Signaling Adap

Sherry L. Niessen, B. Cravatt, A. Gaultier, 2022 .

Proteomic analysis of the coagulation reaction in plasma and whole blood using PROTOMAP

Sherry L. Niessen, Heather S Hoover, A. Gale, 2011, Proteomics.

Dim1p Is Required for Efficient Splicing and Export of mRNA Encoding Lid1p, a Component of the Fission Yeast Anaphase-Promoting Complex

J. Yates, K. Gould, Sherry L. Niessen, 2005, Eukaryotic Cell.

Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors

Graham M. West, Sherry L. Niessen, Claude Ambroise, 2016, Nature Communications.

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension.

John R Yates, Karen Oegema, Iain M Cheeseman, 2004, Genes & development.

Mps1 Phosphorylation of Dam1 Couples Kinetochores to Microtubule Plus Ends at Metaphase

J. Yates, T. Davis, E. Muller, 2006, Current Biology.

E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells.

G. Sauvageau, Martin Sauvageau, Sherry L. Niessen, 2006, Genes & development.

Affinity purification of protein complexes in C. elegans.

K. Oegema, J. Yates, E. Zanin, 2011, Methods in cell biology.

activity of this receptor pathway by LDL receptor-related protein explains the antiinflammatory Regulation of tumor necrosis factor receptor-1 and the IKK-NF-{kappa}B

Sherry L. Niessen, B. Cravatt, A. Gaultier, 2009 .

activity of this receptor related protein explains the antiinflammatory − pathway by LDL receptor B κ Regulation of tumor necrosis factor receptor-1 and the IKK

Sherry L. Niessen, B. Cravatt, A. Gaultier, 2008 .

IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration.

Peter T. Yu, Sherry L. Niessen, Heather S Hoover, 2011, Carcinogenesis.

Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling.

K. Ching, Sherry L. Niessen, K. Jensen-Pergakes, 2020, Cell reports.

A Structurally Distinct Human Mycoplasma Protein that Generically Blocks Antigen-Antibody Union

Daniel R. Salomon, Richard A. Lerner, Andrew B. Ward, 2014, Science.

Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates.

L. Parsons, J. Chang, Sherry L. Niessen, 2012, Chemistry & biology.

Pseudomonas syringae pv. syringae Uses Proteasome Inhibitor Syringolin A to Colonize from Wound Infection Sites

Sherry L. Niessen, M. Kaiser, T. Shindo, 2013, PLoS pathogens.

The RON‐receptor regulates pancreatic cancer cell migration through phosphorylation‐dependent breakdown of the hemidesmosome

Peter T. Yu, Sherry L. Niessen, Heather S Hoover, 2012, International journal of cancer.

A Hormone-Dependent Module Regulating Energy Balance

John B. Thomas, J. Yates, Sherry L. Niessen, 2011, Cell.

Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer.

J. Chang, D. Nomura, J. Long, 2011, Chemistry & biology.

Diversity of Serine Hydrolase Activities of Unchallenged and Botrytis-infected Arabidopsis thaliana*S

Sherry L. Niessen, Heather S Hoover, B. Cravatt, 2009, Molecular & Cellular Proteomics.

RBBP9: A tumor-associated serine hydrolase activity required for pancreatic neoplasia

D. Tarin, Sherry L. Niessen, B. Cravatt, 2009, Proceedings of the National Academy of Sciences.

A chemical biology approach to interrogate quorum-sensing regulated behaviors at the molecular and cellular level.

Samuel I. Miller, Sherry L. Niessen, B. Cravatt, 2013, Chemistry & biology.

Click-generated triazole ureas as ultrapotent, in vivo-active serine hydrolase inhibitors

Brent R. Martin, Sherry L. Niessen, B. Cravatt, 2011, Nature chemical biology.

Phosphorylation of the chromosomal passenger protein Bir1 is required for localization of Ndc10 to the spindle during anaphase and full spindle elongation.

J. Yates, T. Davis, Scott D. Anderson, 2005, Molecular biology of the cell.

Major Cys protease activities are not essential for senescence in individually darkened Arabidopsis leaves

A. Millar, Sherry L. Niessen, T. Shindo, 2017, BMC Plant Biology.

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Sherry L. Niessen, S. Kaiser, J. Kath, 2016, Chembiochem : a European journal of chemical biology.

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.

L. Lum, K. Gajiwala, Sherry L. Niessen, 2021, The Journal of biological chemistry.

Sherry L. Niessen, B. Cravatt, A. Gaultier, 2010, Journal of proteome research.

Identification of a selective, activity-based probe for glyceraldehyde 3-phosphate dehydrogenases.

C. Ottmann, Sherry L. Niessen, M. Kaiser, 2012, Angewandte Chemie.

Introduction to Peptides and Proteins

Astrid Graslund, Benjamin F. Cravatt, Ülo Langel, 2009 .

Corrigendum: Click-generated triazole ureas as ultrapotent in vivo –active serine hydrolase inhibitors

Brent R. Martin, Sherry L. Niessen, B. Cravatt, 2012 .

Discovery of Enzymatic Targets of Transcriptional Activators via in Vivo Covalent Chemical Capture.

Chinmay Y. Majmudar, Sherry L. Niessen, B. Cravatt, 2016, Journal of the American Chemical Society.

Effects of Activating Mutations on EGFR Cellular Protein Turnover and Amino Acid Recycling Determined Using SILAC Mass Spectrometry

Sherry L. Niessen, Ted O. Johnson, S. Weinrich, 2015, International journal of cell biology.

The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p

J. Yates, P. Brennwald, P. Novick, 2006, The Journal of cell biology.

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

Sherry L. Niessen, B. Cravatt, A. Adibekian, 2010, Proceedings of the National Academy of Sciences.

Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer.

J. Chang, D. Nomura, J. Long, 2011, Chemistry & biology.

Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor.

Sherry L. Niessen, A. Gaultier, M. Linton, 2008, Blood.

Breast Cancer Cell Lines Grown in Vivo

Nasreen S Jessani, Sherry L. Niessen, B. Cravatt, 2005 .

K. Gajiwala, N. Sach, Sherry L. Niessen, 2016, Journal of medicinal chemistry.

IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration.

Peter T. Yu, Sherry L. Niessen, B. Cravatt, 2011, Carcinogenesis.

The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p

J. Yates, P. Brennwald, P. Novick, 2006, The Journal of cell biology.

Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly.

K. Oegema, A. Desai, Huilin Zhou, 2013, Developmental cell.