R. Ladenstein

发表

Studies on the lumazine synthase/riboflavin synthase complex of Bacillus subtilis: crystal structure analysis of reconstituted, icosahedral beta-subunit capsids with bound substrate analogue inhibitor at 2.4 A resolution.

R. Huber, A. Bacher, K. Ritsert, 1995, Journal of molecular biology.

Rigidity versus flexibility: the dilemma of understanding protein thermal stability

Lennart Nilsson, Andrey Karshikoff, L. Nilsson, 2015, The FEBS journal.

Proteins from thermophilic and mesophilic organisms essentially do not differ in packing.

A. Karshikoff, R. Ladenstein, A. Karshikoff, 1998, Protein engineering.

Ion pairs and the thermotolerance of proteins from hyperthermophiles: a "traffic rule" for hot roads.

A. Karshikoff, R. Ladenstein, A. Karshikoff, 2001, Trends in biochemical sciences.

X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons.

A. Bacher, R. Ladenstein, X. Zhang, 2001, Journal of molecular biology.

Proteins from hyperthermophiles: stability and enzymatic catalysis close to the boiling point of water.

R. Ladenstein, G. Antranikian, R Ladenstein, 1998, Advances in biochemical engineering/biotechnology.

Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers

Nannan Yang, Ida Helene Steen, R. Ladenstein, 2007, Extremophiles.

Refined crystal structure of ascorbate oxidase at 1.9 A resolution.

L Avigliano, M Bolognesi, R. Huber, 1992, Journal of molecular biology.

Expression, purification, crystallization and preliminary X-ray analysis of a nucleoside kinase from the hyperthermophile Methanocaldococcus jannaschii.

R. Ladenstein, W. Meining, P. Schönheit, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Optimization of the electrostatic interactions in proteins of different functional and folding type

A. Karshikoff, R. Ladenstein, V. Spassov, 1994, Protein science : a publication of the Protein Society.

Architecture of nonspecific protein–DNA interactions in the Sso7d–DNA complex

Stefan Knapp, S. Knapp, R. Ladenstein, 1998, Nature Structural Biology.

The refined structure of the selenoenzyme glutathione peroxidase at 0.2-nm resolution.

A Wendel, R. Ladenstein, O. Epp, 1983, European journal of biochemistry.

DNA Topoisomerase VI Generates ATP-dependent Double-strand Breaks with Two-nucleotide Overhangs*

J. Lebbink, P. Forterre, R. Ladenstein, 2001, The Journal of Biological Chemistry.

Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase.

A. Bacher, E. Morgunova, N. Foloppe, 2010, Bioorganic & medicinal chemistry.

Protein Stabilisation by Compatible Solutes: Effect of Mannosylglycerate on Unfolding Thermodynamics and Activity of Ribonuclease A

S. Knapp, H. Santos, R. Ladenstein, 2003, Chembiochem : a European journal of chemical biology.

In vitro DNA binding of the archaeal protein Sso7d induces negative supercoiling at temperatures typical for thermophilic growth.

S. Knapp, P. Forterre, R. Ladenstein, 1998, Nucleic acids research.

Substrate-induced redox change of selenium in glutathione peroxidase studied by x-ray photoelectron spectroscopy.

R. Ladenstein, A. Wendel, G. Sawatzki, 1975, Biochimica et Biophysica Acta.

Medium- and short-chain dehydrogenase/reductase gene and protein families

R. Ladenstein, J. Benach, J. Winberg, 2008, Cellular and Molecular Life Sciences.

Glutathione transferase from bovine placenta. Preparation, biochemical characterization, crystallization, and preliminary crystallographic analysis of a neutral class PI enzyme.

R. Ladenstein, J. Schäffer, O. Gallay, 1988, The Journal of biological chemistry.

The effect of storage and heat treatment on glutathione peroxidase in bovine milk and whey

R. Ladenstein, B. Ren, H. Lindmark-Månsson, 2001 .

Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: a member of a novel protein family related to protein disulfide-isomerase.

R. Ladenstein, M. Rossi, B. Ren, 2004, European journal of biochemistry.

S-transferase incomplexwithglutathione sulfonate at 2.3A resolution

P. Reinemer, R. Ladenstein, O. Gallay, 2005 .

Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.

J. Lebbink, K. Berndt, R. Ladenstein, 2002, Biochemistry.

The molecular chaperonin TF55 from the Thermophilic archaeon Sulfolobus solfataricus. A biochemical and structural characterization.

S. Knapp, H. Jörnvall, T. Bergman, 1994, Journal of molecular biology.

Structure of bacterial 3beta/17beta-hydroxysteroid dehydrogenase at 1.2 A resolution: a model for multiple steroid recognition.

K. Berndt, H. Jörnvall, G. Bricogne, 2002, Biochemistry.

Crystallization and preliminary X-ray analysis of a RecB-family nuclease from the archaeon Pyrococcus abyssi.

R. Ladenstein, B. Ren, H. Myllykallio, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray structure analysis of isocitrate dehydrogenase from two hyperthermophiles, Aeropyrum pernix and Thermotoga maritima.

R. Ladenstein, I. Steen, T. Lien, 2002, Acta crystallographica. Section D, Biological crystallography.

Human spermatid‐specific thioredoxin‐1 (Sptrx‐1) is a two‐domain protein with oxidizing activity

K. Berndt, J. Gustafsson, T. Kieselbach, 2002, FEBS letters.

Crystallization and preliminary crystallographic analysis of the recombinant N-terminal domain of riboflavin synthase.

A. Bacher, R. Ladenstein, W. Meining, 2001, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary X-ray crystallographic studies of the thermoactive pullulanase type I, hydrolyzing alpha-1,6 glycosidic linkages, from Fervidobacterium pennivorans Ven5.

J. Lebbink, R. Ladenstein, G. Antranikian, 2000, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary crystallographic analysis of Rieske iron-sulfur protein II (soxF) from sulfolobus acidocaldarius.

R. Ladenstein, C. Schmidt, G. Schäfer, 2000, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary crystallographic analysis of an amylopullulanase from the hyperthermophilic archaeon Pyrococcus woesei

S. Knapp, R. Ladenstein, G. Antranikian, 1995, Proteins.

Preliminary crystallographic study of ascorbic acid oxidase from green zucchini squash

R. Ladenstein, S. Palmieri, A. Marchesini, 1979, FEBS letters.

Crystallographic data of the selenoenzyme glutathione peroxidase.

R. Ladenstein, A. Wendel, 1976, Journal of molecular biology.

Structural analysis of the Sulfolobus solfataricus MCM protein N-terminal domain†

R. Ladenstein, M. Rossi, F. Pisani, 2008, Nucleic acids research.

Electrostatic interactions in proteins: Contribution to structure-function relationships and stability

R. Ladenstein, A. Karshikoff, A. Koumanov, 2001 .

X-ray crystal structure of the blue oxidase ascorbate oxidase from zucchini. Analysis of the polypeptide fold and a model of the copper sites and ligands.

R. Huber, M. Bolognesi, A. Finazzi-Agro’, 1989, Journal of molecular biology.

Formation of metal nanoclusters on specific surface sites of protein molecules.

R. Huber, A. Bacher, R. Ladenstein, 2002, Journal of molecular biology.

The structure of the N-terminal domain of riboflavin synthase in complex with riboflavin at 2.6A resolution.

Winfried Meining, A. Bacher, R. Ladenstein, 2003, Journal of molecular biology.

Evidence for local 32 symmetry in homotrimeric riboflavin synthase of Escherichia coli.

A. Bacher, R. Ladenstein, W. Meining, 1998, Journal of structural biology.

The 2.9A resolution crystal structure of malate dehydrogenase from Archaeoglobus fulgidus: mechanisms of oligomerisation and thermal stabilisation.

R. Ladenstein, A. Karshikoff, D. Madern, 2004, Journal of molecular biology.

Metamorphosis of an Enzyme

A. Bacher, R. Ladenstein, X. Zhang, 2009 .

Biosynthesis of Flavins

W. Eisenreich, A. Bacher, R. Ladenstein, 1993 .

Refined crystal structure of a superoxide dismutase from the hyperthermophilic archaeon Sulfolobus acidocaldarius at 2.2 A resolution.

S. Knapp, R. Ladenstein, S. Kardinahl, 1999, Journal of molecular biology.

Structure-function relationships in short-chain alcohol dehydrogenases

R. Ladenstein, J. Benach, J. Winberg, 2008 .

Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability.

R. Ladenstein, I. Steen, N. Birkeland, 2005, Journal of molecular biology.

An intact eight‐membered water chain in drosophilid alcohol dehydrogenases is essential for optimal enzyme activity

I. Sylte, E. Morgunova, R. Ladenstein, 2012, The FEBS journal.

Drosophila alcohol dehydrogenase: acetate-enzyme interactions and novel insights into the effects of electrostatics on catalysis.

R. Ladenstein, J. Benach, J. Svendsen, 2005, Journal of molecular biology.

The catalytic mechanism of Drosophila alcohol dehydrogenase: Evidence for a proton relay modulated by the coupled ionization of the active site Lysine/Tyrosine pair and a NAD+ ribose OH switch

R. Ladenstein, A. Karshikoff, J. Benach, 2003, Proteins.

Genesis of Drosophila ADH: the shaping of the enzymatic activity from a SDR ancestor.

R. Ladenstein, J. Benach, R. Gonzàlez-Duarte, 2001, Chemico-biological interactions.

Structure-function relationships in Drosophila melanogaster alcohol dehydrogenase allozymes ADH(S), ADH(F) and ADH(UF), and distantly related forms.

R. Ladenstein, J. Benach, R. Gonzàlez-Duarte, 2000, European journal of biochemistry.

The refined crystal structure of Drosophila lebanonensis alcohol dehydrogenase at 1.9 A resolution.

R. Ladenstein, J. Benach, R. Gonzàlez-Duarte, 1998, Journal of molecular biology.

Drosophila alcohol dehydrogenase: evaluation of Ser139 site‐directed mutants

R. Ladenstein, J. Benach, R. Gonzàlez-Duarte, 1997, FEBS letters.

The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.

R. Ladenstein, J. Benach, R. Gonzàlez-Duarte, 1999, Journal of molecular biology.

Lumazine Synthase from Candida albicans as an Anti-fungal Target Enzyme

Markus Fischer, Ekaterina Morgunova, A. Bacher, 2007, Journal of Biological Chemistry.

Electrostatic properties of two porin channels from Escherichia coli.

A. Karshikoff, R. Ladenstein, S. Cowan, 1994, Journal of molecular biology.

Enzyme catalysis via control of activation entropy: site-directed mutagenesis of 6,7-dimethyl-8-ribityllumazine synthase.

R. Huber, A. Bacher, R. Ladenstein, 2003, Journal of molecular biology.

Critical Residues for Structure and Catalysis in Short-chain Dehydrogenases/Reductases*

Erik Nordling, Stefan Knapp, Udo Oppermann, 2002, The Journal of Biological Chemistry.

FLEXIBILITY OF AN ARGININE SIDE CHAIN AT A DNA-PROTEIN INTERFACE

S. Knapp, R. Ladenstein, H. Berglund, 1995 .

Structures of heat shock factor trimers bound to DNA

R. Ladenstein, Dacheng Wang, A. Punekar, 2021, iScience.

MD simulation of high-resolution X-ray structures reveals post-translational modification dependent conformational changes in HSF-DNA interaction

R. Ladenstein, Dacheng Wang, A. Punekar, 2016, Protein & Cell.

Md Simulation of Crystal Structures Reveals Post-translational Modification Dependent Conformational Changes in Heat Shock Factor -dna Interaction Protein Expression and Purification……………………………………………2 Crystallization and Diffraction Data Collection…………………………………3 Structure Determination and Refinemen

R. Ladenstein, Dacheng Wang, A. Punekar, 2022 .

Solution structure and DNA-binding properties of a thermostable protein from the archaeon Sulfolobus solfataricus

S. Knapp, R. Ladenstein, T. Härd, 1994, Nature Structural Biology.

Crystal structure of the archaeal heat shock regulator from Pyrococcus furiosus: a molecular chimera representing eukaryal and bacterial features.

R. Ladenstein, M. Thomm, Ann-Kathrin Wenke, 2007, Journal of molecular biology.

Some observations of a correlation between the symmetry of large heavy-atom complexes and their binding sites on proteins.

R. Huber, A. Bacher, R. Ladenstein, 1987, Journal of molecular biology.

The three‐dimensional structure of class pi glutathione S‐transferase in complex with glutathione sulfonate at 2.3 A resolution.

R. Huber, P. Reinemer, R. Ladenstein, 1991, The EMBO journal.

The multi-layered structure of Dps with a novel di-nuclear ferroxidase center.

R. Ladenstein, T. Kajino, B. Ren, 2003, Journal of molecular biology.

Active site directed mutagenesis of 3 beta/17 beta-hydroxysteroid dehydrogenase establishes differential effects on short-chain dehydrogenase/reductase reactions.

B. Persson, K. Berndt, H. Jörnvall, 1997, Biochemistry.

Electrostatic evidence for the activation of the glutathione thiol by Tyr7 in pi-class glutathione transferases.

R. Huber, P. Reinemer, A. Karshikoff, 1993, European journal of biochemistry.

A protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus contains two thioredoxin fold units

Niels Volkmann, William Lehman, Dorit Hanein, 1998, Nature Structural Biology.

Thermal unfolding of small proteins with SH3 domain folding pattern

S. Knapp, M. Vihinen, K. Berndt, 1998, Proteins.

A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus.

Markus Fischer, Winfried Meining, A. Bacher, 2003, Journal of molecular biology.

Human hereditary glutathione synthetase deficiency: kinetic properties of mutant enzymes.

L. Nilsson, R. Ladenstein, S. Norgren, 2004, The Biochemical journal.

Extrinsic protein stabilization by the naturally occurring osmolytes β-hydroxyectoine and betaine

S. Knapp, R. Ladenstein, E. Galinski, 1999, Extremophiles.

Well ordered crystals of a short-chain alcohol dehydrogenase from Drosophila lebanonensis: re-evaluation of the crystallographic data and rotation-function analysis.

A. Karshikoff, R. Ladenstein, R. Gonzàlez-Duarte, 1995, Acta crystallographica. Section D, Biological crystallography.

Second career of a biosynthetic enzyme: Lumazine synthase as a virus-like nanoparticle in vaccine development

E. Morgunova, R. Ladenstein, 2020, Biotechnology reports.

Comparison of Isocitrate Dehydrogenase from Three Hyperthermophiles Reveals Differences in Thermostability, Cofactor Specificity, Oligomeric State, and Phylogenetic Affiliation*

R. Ladenstein, D. Madern, I. Steen, 2001, The Journal of Biological Chemistry.

A protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus contains two thioredoxin fold units

R. Ladenstein, M. Rossi, B. Ren, 1998, Nature Structural Biology.

Structure and function of a novel endonuclease acting on branched DNA substrates

R. Ladenstein, B. Ren, H. Myllykallio, 2009, The EMBO journal.

Thermal unfolding of the DNA-binding protein Sso7d from the hyperthermophile Sulfolobus solfataricus.

S. Knapp, K. Berndt, B. Atanasov, 1996, Journal of molecular biology.

Exploitation of Geometric Redundancies as a Source of Phase Information in X-Ray Structure Analysis of Symmetric Protein Assemblies — Including a worked example: the three-dimensional structure of the icosahedral β60 capsid of heavy riboflavin synthase from Bacillus subtilis

A. Bacher, R. Ladenstein, 1989 .

Reconsideration of an early dogma, saying “there is no evidence for disulfide bonds in proteins from archaea”

R. Ladenstein, B. Ren, 2007, Extremophiles.

Protein disulfides and protein disulfide oxidoreductases in hyperthermophiles

R. Ladenstein, B. Ren, 2006, The FEBS journal.

Structure and function of a novel endonuclease acting on branched DNA

R. Ladenstein, H. Myllykallio, L. Meslet-Cladière, 2009 .

Multiple assembly states of lumazine synthase: a model relating catalytic function and molecular assembly.

L. Xing, A. Bacher, D. Svergun, 2006, Journal of molecular biology.

The lumazine synthase/riboflavin synthase complex of Bacillus subtilis. X-ray structure analysis of hollow reconstituted beta-subunit capsids.

R. Huber, A. Bacher, K. Ritsert, 1994, European journal of biochemistry.

Heavy riboflavin synthase from Bacillus subtilis. Crystal structure analysis of the icosahedral beta 60 capsid at 3.3 A resolution.

R. Huber, A. Bacher, R. Ladenstein, 1988, Journal of molecular biology.

The lumazine synthase/riboflavin synthase complex: shapes and functions of a highly variable enzyme system

A. Bacher, R. Ladenstein, M. Fischer, 2013, The FEBS journal.

Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution.

M W Parker, R. Huber, P. Reinemer, 1992, Journal of molecular biology.

Structure analysis and molecular model of the selenoenzyme glutathione peroxidase at 2.8 A resolution.

R. Huber, R. Ladenstein, K. Bartels, 1979, Journal of molecular biology.

Crystal structure of glutamate dehydrogenase from the hyperthermophilic eubacterium Thermotoga maritima at 3.0 A resolution.

S. Knapp, W. D. de Vos, D. Rice, 1997, Journal of molecular biology.

Ultrahigh-resolution study on Pyrococcus abyssi rubredoxin: II. Introduction of an O–H···Sγ–Fe hydrogen bond increased the reduction potential by 65 mV

R. Ladenstein, C. Schmidt, H. Bönisch, 2007, JBIC Journal of Biological Inorganic Chemistry.

Ultrahigh-resolution study on Pyrococcus abyssi rubredoxin. I. 0.69 A X-ray structure of mutant W4L/R5S.

Pierre Bianco, R. Ladenstein, C. Schmidt, 2005, Acta crystallographica. Section D, Biological crystallography.

The crystal structure of seleno-glutathione peroxidase from human plasma at 2.9 A resolution.

R. Ladenstein, B. Ren, W. Huang, 1997, Journal of molecular biology.

Thermodynamic and kinetic stability of a large multi-domain enzyme from the hyperthermophile Aeropyrum pernix

R. Ladenstein, R. Chiaraluce, V. Consalvi, 2010, Extremophiles.

Thermal unfolding and conformational stability of the recombinant domain II of glutamate dehydrogenase from the hyperthermophile Thermotoga maritima.

S. Knapp, A. Karshikoff, R. Ladenstein, 2000, Protein engineering.

The optimization of protein‐solvent interactions: Thermostability and the role of hydrophobic and electrostatic interactions

A. Karshikoff, R. Ladenstein, V. Spassov, 1995, Protein science : a publication of the Protein Society.

Optimization of the electrostatic interactions between ionized groups and peptide dipoles in proteins

A. Karshikoff, R. Ladenstein, V. Spassov, 1997, Protein science : a publication of the Protein Society.

Electrostatic effects in a large enzyme complex: Subunit interactions and electrostatic potential field of the icosahedral β60 capsid of heavy riboflavin synthase

R. Ladenstein, A. Karshikov, Andrej Karshikov, 1989, Proteins.

Heat Capacity, Configurational Entropy, and the Role of Ionic Interactions in Protein Thermostability

R. Ladenstein, 2008 .

The phosphofructokinase-B (MJ0406) from Methanocaldococcus jannaschii represents a nucleoside kinase with a broad substrate specificity

R. Ladenstein, P. Schönheit, T. Hansen, 2006, Extremophiles.

DNA-binding surface of the Sso7d protein from Sulfolobus solfataricus.

S. Knapp, A. Karshikoff, R. Ladenstein, 1995, Journal of molecular biology.

Two-dimensional crystallization of the chaperonin TF55 from the hyperthermophilic archaeon Sulfolobus solfataricus.

S. Knapp, R. Ladenstein, P. Koeck, 1998, Journal of structural biology.

Crystallization and crystal packing of recombinant 3 (or 17) beta-hydroxysteroid dehydrogenase from Comamonas testosteroni ATTC 11996.

S. Knapp, H. Jörnvall, R. Ladenstein, 1996, European journal of biochemistry.

Design, synthesis, and biochemical evaluation of 1,5,6,7-tetrahydro-6,7-dioxo-9-D-ribitylaminolumazines bearing alkyl phosphate substituents as inhibitors of lumazine synthase and riboflavin synthase.

A. Bacher, R. Ladenstein, M. Fischer, 2005, The Journal of organic chemistry.

Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors.

Markus Fischer, Ekaterina Morgunova, Winfried Meining, 2005, Biochemistry.

The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue.

A. Bacher, R. Ladenstein, W. Meining, 2000, Journal of molecular biology.

The N-terminal domain of riboflavin synthase in complex with riboflavin

A. Bacher, R. Ladenstein, W. Meining, 2004 .

Biological Crystallography Structural Study and Thermodynamic Characterization of Inhibitor Binding to Lumazine Synthase from Bacillus Anthracis

A. Bacher, E. Morgunova, R. Ladenstein, 2022 .

Design, Synthesis, and Biochemical Evaluation of 1,5,6,7‐Tetrahydro‐6,7‐dioxo‐9‐D‐Ribitylaminolumazines Bearing Alkyl Phosphate Substituents as Inhibitors of Lumazine Synthase and Riboflavin Synthase.

A. Bacher, R. Ladenstein, M. Cushman, 2005 .

Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis

Markus Fischer, Ekaterina Morgunova, A. Bacher, 2006, The FEBS journal.

The lumazine synthase-riboflavin synthase complex of Bacillus subtilis. Crystallization of reconstituted icosahedral beta-subunit capsids.

A. Bacher, R. Ladenstein, K. Schott, 1990, The Journal of biological chemistry.

Crystallization and preliminary X-ray diffraction study of heavy riboflavin synthase from Bacillus subtilis.

A. Bacher, R. Ladenstein, H. Ludwig, 1983, The Journal of biological chemistry.

A new series of N-[2,4-dioxo-6-d-ribitylamino-1,2,3,4-tetrahydropyrimidin-5-yl]oxalamic acid derivatives as inhibitors of lumazine synthase and riboflavin synthase: design, synthesis, biochemical evaluation, crystallography, and mechanistic implications.

A. Bacher, E. Morgunova, R. Ladenstein, 2008, The Journal of organic chemistry.

Multiple assembly states of lumazine synthase

A. Bacher, D. Svergun, R. Ladenstein, 2004 .

Electron microscopy of decorated crystals for the determination of crystallographic rotation and translation parameters in large protein complexes.

R. Huber, W. Baumeister, A. Bacher, 1992, Journal of molecular biology.

Correlation of metal decoration and topochemistry on protein surfaces.

R. Huber, W. Baumeister, A. Bacher, 1991, Journal of molecular biology.

The structure of the soluble domain of an archaeal Rieske iron-sulfur protein at 1.1 A resolution.

R. Ladenstein, C. Schmidt, G. Schäfer, 2002, Journal of molecular biology.

Heavy riboflavin synthase from Bacillus subtilis. Particle dimensions, crystal packing and molecular symmetry.

R. Huber, A. Bacher, R. Ladenstein, 1986, Journal of molecular biology.

Crystallization and preliminary crystallographic characterization of GTP cyclohydrolase I from Escherichia coli.

R. Huber, A. Bacher, R. Ladenstein, 1992, Journal of molecular biology.

SYNTHASE/RIBOFLAVIN SYNTHASE COMPLEX OF BACILLUS SUBTILIS

R. Huber, A. Bacher, K. Ritsert, 1996 .

Heavy riboflavin synthase of Bacillus subtilis. Primary structure of the beta subunit.

A. Bacher, R. Ladenstein, F. Lottspeich, 1987, The Journal of biological chemistry.

Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface.

J. Lebbink, S. Knapp, W. D. de Vos, 1999, Journal of molecular biology.

Dynamic arrangement of ion pairs and individual contributions to the thermal stability of the cofactor-binding domain of glutamate dehydrogenase from Thermotoga maritima.

Lennart Nilsson, L. Nilsson, R. Ladenstein, 2007, Biochemistry.

The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima

R. Ladenstein, D. Madern, I. Steen, 2006, The FEBS journal.

Isolation and structure of repressor‐like proteins from the archaeon Sulfolobus solfataricus

S. Knapp, H. Jörnvall, R. Ladenstein, 1998, FEBS letters.

Thermodynamic characterization of non-sequence-specific DNA-binding by the Sso7d protein from Sulfolobus solfataricus.

S. Knapp, R. Ladenstein, T. Härd, 1998, Journal of molecular biology.

The Structure of the Selenoenzyme GSH Peroxidase

R. Ladenstein, A. Wendel, Otto Epp, 1981 .

CRYSTAL STRUCTURE ANALYSIS OF LUMAZINE SYNTHASE FROM AQUIFEX AEOLICUS

A. Bacher, R. Ladenstein, X. Zhang, 2001 .

Structural role of conserved Asn179 in the short-chain dehydrogenase/reductase scaffold.

K. Berndt, H. Jörnvall, R. Ladenstein, 2001, Biochemical and biophysical research communications.

Class π glutathione S-transferase from pig lung

R. Huber, P. Reinemer, R. Ladenstein, 1991 .

Crystallization and Preliminary X-Ray Structure Analysis of a Hyperthermostable Thioltransferase from the ArchaeonPyrococcus furiosus

R. Ladenstein, M. Rossi, B. Ren, 1997 .

Protein disulfide oxidoreductase from Pyrococcus furiosus: structural properties.

R. Ladenstein, B. Ren, 2001, Methods in enzymology.

Structure of Methanocaldococcus jannaschii nucleoside kinase: an archaeal member of the ribokinase family.

R. Ladenstein, W. Meining, P. Schönheit, 2006, Acta crystallographica. Section D, Biological crystallography.

Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. I. Introduction of a six-residue ion-pair network in the hinge region.

J. Lebbink, S. Knapp, W. D. de Vos, 1998, Journal of molecular biology.

Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment.

E. Morgunova, R. Ladenstein, S. MacNeill, 2009, Acta crystallographica. Section D, Biological crystallography.

Rigidity versus flexibility: the dilemma of understanding protein thermal stability

L. Nilsson, R. Ladenstein, A. Karshikoff, 2015, The FEBS journal.

Of crystals, structure factors and diffraction images

Ekaterina Morgunova, E. Morgunova, R. Ladenstein, 2008 .