M. Miley

发表

Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer.

Bryan S. Der, B. Kuhlman, T. Szyperski, 2012, Journal of the American Chemical Society.

Increasing sequence diversity with flexible backbone protein design: the complete redesign of a protein hydrophobic core.

B. Kuhlman, T. Szyperski, M. Machius, 2012, Structure.

Computational design of a symmetric homodimer using β-strand assembly

Brian Kuhlman, Ashutosh Tripathy, B. Kuhlman, 2011, Proceedings of the National Academy of Sciences.

P-glycoprotein targeted photodynamic therapy of chemoresistant tumors using recombinant Fab fragment conjugates.

M. Miley, Zibo Li, X. Ming, 2018, Biomaterials science.

Discovery of Macrocyclic Pyrimidines as MerTK‐Specific Inhibitors

S. Frye, M. Machius, M. Miley, 2017, ChemMedChem.

Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis.

S. Frye, W. Janzen, M. Machius, 2013, Journal of medicinal chemistry.

Enhanced Immune Presentation of a Single-chain Major Histocompatibility Complex Class I Molecule Engineered to Optimize Linkage of a C-terminally Extended Peptide*

D. Fremont, M. Miley, L. Lybarger, 2003, Journal of Biological Chemistry.

Function Protein 1 Consistent with an Immunological Biochemical Features of the MHC-Related Lonnie

D. Fremont, M. Miley, S. Gilfillan, 2003 .

Biochemical Features of the MHC-Related

D. Fremont, M. Miley, S. Gilfillan, 2003 .

Evidence for MR1 Antigen Presentation to Mucosal-associated Invariant T Cells*

D. Fremont, M. Miley, M. Cella, 2005, Journal of Biological Chemistry.

Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses.

M. Miley, J. DeSimone, A. D. de Silva, 2018, Bioconjugate chemistry.

In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers

R. Baric, M. Miley, L. Premkumar, 2017, Scientific Reports.

Oligomeric state of the ZIKV E protein defines protective immune responses

M. Miley, A. D. de Silva, Stefan W. Metz, 2019, Nature Communications.

Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype

M. Miley, J. DeSimone, A. D. de Silva, 2018, PLoS neglected tropical diseases.

Dissecting the human serum antibody response to secondary dengue virus infections

Bhumi P. Patel, E. Harris, M. Miley, 2017, PLoS neglected tropical diseases.

Physiological temperatures reduce dimerization of dengue and Zika virus recombinant envelope proteins

B. Kuhlman, M. Miley, A. Bobkov, 2018, The Journal of Biological Chemistry.

Development of Envelope Protein Antigens To Serologically Differentiate Zika Virus Infection from Dengue Virus Infection

A. Sette, E. Harris, M. Miley, 2017, Journal of Clinical Microbiology.

Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

M. Miley, J. DeSimone, A. D. de Silva, 2016, PLoS neglected tropical diseases.

Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.

D. A. O’Brien, M. Machius, M. Miley, 2016, Molecular human reproduction.

Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7.

M. Miley, M. Redinbo, Matthew R Redinbo, 2007, Journal of molecular biology.

Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma.

David B. Darr, N. Sharpless, W. Jeck, 2014, Cancer discovery.

Functional Characterization of the Multidomain F Plasmid TraI Relaxase-Helicase*

M. Miley, M. Redinbo, D. McNamara, 2011, The Journal of Biological Chemistry.

The role of mhc polymorphism in anti-microbial resistance.

D. Fremont, M. Miley, I. Messaoudi, 2004, Microbes and infection.

Functional Evidence That Conserved TCR CDRα3 Loop Docking Governs the Cross-Recognition of Closely Related Peptide:Class I Complexes1

D. Fremont, M. Miley, I. Messaoudi, 2001, The Journal of Immunology.

Biochemical Features of the MHC-Related Protein 1 Consistent with an Immunological Function1

D. Fremont, M. Miley, L. Lybarger, 2003, The Journal of Immunology.

Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution

Daved H. Fremont, D. Fremont, M. Miley, 2004, The Journal of experimental medicine.

Structural and Functional Consequences of Altering a Peptide MHC Anchor Residue1

C. Nelson, D. Fremont, M. Miley, 2001, The Journal of Immunology.

Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors.

S. Frye, W. Janzen, M. Machius, 2013, Journal of medicinal chemistry.

Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia.

S. Frye, W. Janzen, M. Machius, 2012, ACS medicinal chemistry letters.

Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia

Amy Lynnette Van Deusen, S. Frye, W. Janzen, 2012 .

Structural and Functional Consequences of Altering a Peptide MHC Anchor Residue

C. Nelson, D. Fremont, M. Miley, 2001 .

Data-driven construction of anti-tumor agents with controlled polypharmacology.

Laura E. Herring, S. Frye, M. Miley, 2019, Journal of the American Chemical Society.

In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers

R. Baric, M. Miley, L. Premkumar, 2017, Scientific Reports.

The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families

M. Miley, M. Redinbo, S. Bratton, 2010, Drug metabolism reviews.

The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis

A. Goldman, G. Miller, M. Finel, 2008, Drug Metabolism and Disposition.

Altering a Peptide MHC Anchor Residue Structural and Functional Consequences of

C. Nelson, D. Fremont, M. Miley, 2001 .

Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors.

S. Frye, M. Machius, M. Miley, 2016, ACS medicinal chemistry letters.

Computational design of a symmetric homodimer using β-strand assembly

B. Kuhlman, P. B. Stranges, M. Machius, 2011, Proceedings of the National Academy of Sciences.

Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer.

Bryan S. Der, B. Kuhlman, T. Szyperski, 2012, Journal of the American Chemical Society.

Structural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein α Subunit Mutants*

B. Kuhlman, D. Sammond, M. Machius, 2010, The Journal of Biological Chemistry.

Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis.

S. Frye, M. Machius, M. Miley, 2013, Journal of medicinal chemistry.

Discovery of Macrocyclic Pyrimidines as MerTK‐Specific Inhibitors

S. Frye, M. Machius, M. Miley, 2017, ChemMedChem.