A. Laganowsky

发表

Structure of a Designed Protein Cage that Self-Assembles into a Highly Porous Cube

Greg L. Hura, T. Yeates, J. Tainer, 2014, Nature chemistry.

Membrane proteins bind lipids selectively to modulate their structure and function

C. Robinson, E. Reading, A. Laganowsky, 2014, Nature.

Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.

A. Laganowsky, B. Chenna, T. Meek, 2021, Journal of medicinal chemistry.

Towards a Pharmacophore for Amyloid

David Eisenberg, Meytal Landau, Michael R. Sawaya, 2011, PLoS biology.

Atomic View of a Toxic Amyloid Small Oligomer

David Eisenberg, Meytal Landau, Duilio Cascio, 2012, Science.

PROTEINSTRUCTUREREPORT Non-3 D domain swapped crystal structure of truncated zebrafish alphaA crystallin

D. Eisenberg, A. Laganowsky, 2010 .

Non‐3D domain swapped crystal structure of truncated zebrafish alphaA crystallin

D. Eisenberg, A. Laganowsky, D. Eisenberg, 2010, Protein science : a publication of the Protein Society.

Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions

Georg K. A. Hochberg, E. Marklund, A. Laganowsky, 2018, Science.

Characterization of Membrane Protein–Lipid Interactions by Mass Spectrometry Ion Mobility Mass Spectrometry

A. Laganowsky, Yang Liu, Xiao Cong, 2017, Journal of The American Society for Mass Spectrometry.

Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry

E. Marklund, C. Robinson, A. Laganowsky, 2021, JACS Au.

Surface induced dissociation as a tool to study membrane protein complexes.

A. Laganowsky, V. Wysocki, Sophie R. Harvey, 2017, Chemical communications.

Allosteric modulation of protein-protein interactions by individual lipid binding events

A. Laganowsky, Xiaowen Liang, Yang Liu, 2017, Nature Communications.

Structural basis of ion transport and inhibition in ferroportin

Jiemin Shen, N. Yan, A. Laganowsky, 2020, Nature Communications.

Allostery revealed within lipid binding events to membrane proteins

C. D. Boone, A. Laganowsky, J. Patrick, 2018, Proceedings of the National Academy of Sciences.

Selective binding of a toxin and phosphatidylinositides to a mammalian potassium channel

A. Laganowsky, Michael L. Poltash, D. Russell, 2019, Nature Communications.

New vehicles allow detergent-free mass spectrometry of membrane protein complexes

C. Robinson, M. Caffrey, A. Laganowsky, 2013, Nature Methods.

Dynamical coupling of intrinsically disordered proteins and their hydration water: comparison with folded soluble and membrane proteins.

D. Eisenberg, A. Laganowsky, F. Gabel, 2012, Biophysical journal.

Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry

E. Marklund, C. Robinson, A. Laganowsky, 2021, JACS Au.

A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins

J. Sacchettini, A. Laganowsky, J. Patrick, 2020, eLife.

A Sec14-like Phosphatidylinositol Transfer Protein Paralog Defines a Novel Class of Heme-binding Proteins With An Unusual Heme Coordination Mechanism

J. Sacchettini, A. Laganowsky, J. Patrick, 2020, bioRxiv.

Development and Evaluation of a Reverse-Entry Ion Source Orbitrap Mass Spectrometer

A. Laganowsky, J. Patrick, Michael L. Poltash, 2018, Journal of The American Society for Mass Spectrometry.

Development of Native MS Capabilities on an Extended Mass Range Q-TOF MS.

A. Laganowsky, D. Russell, Xueyun Zheng, 2020, International journal of mass spectrometry.

Ag+ Ion Binding to Human Metallothionein-2A is Cooperative and Domain Specific.

A. Laganowsky, D. Russell, M. Shirzadeh, 2020, Analytical chemistry.

Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1

A. Laganowsky, C. Altenbach, W. Hubbell, 2017, Proceedings of the National Academy of Sciences.

Evidence for Many Unique Solution Structures for Chymotrypsin Inhibitor 2: A Thermodynamic Perspective Derived from vT-ESI-IMS-MS Measurements.

A. Laganowsky, D. Russell, D. Clemmer, 2020, Journal of the American Chemical Society.

Melting Proteins: Evidence for Multiple Stable Structures upon Thermal Denaturation of Native Ubiquitin from Ion Mobility Spectrometry-Mass Spectrometry Measurements.

A. Laganowsky, D. Russell, D. Clemmer, 2017, Journal of the American Chemical Society.

A Conserved PLPLRT/SD Motif of STING Mediates the Recruitment and Activation of TBK1

B. Sankaran, A. Laganowsky, J. Ji, 2019, Nature.

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

David Eisenberg, Meytal Landau, Duilio Cascio, 2010, Protein science : a publication of the Protein Society.

C-terminal interactions mediate the quaternary dynamics of αB-crystallin

Georg K. A. Hochberg, A. Laganowsky, J. Benesch, 2013, Philosophical Transactions of the Royal Society B: Biological Sciences.

Dimerization and Heme Binding Are Conserved in Amphibian and Starfish Homologues of the microRNA Processing Protein DGCR8

F. Guo, A. Laganowsky, Ian Barr, 2012, PloS one.

Fourier Transform-Ion Mobility-Orbitrap Mass Spectrometer: A Next-Generation Instrument for Native Mass Spectrometry.

A. Laganowsky, Michael L. Poltash, B. Clowers, 2018, Analytical chemistry.

The Amyloid State of Proteins

E. L. Guenther, David Eisenberg, Meytal Landau, 2015 .

Intrinsic GTPase activity of K-RAS monitored by native mass spectrometry.

A. Laganowsky, D. Russell, Z. Moghadamchargari, 2019, Biochemistry.

Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants

A. Laganowsky, Minglei Zhao, D. Russell, 2021, Proceedings of the National Academy of Sciences.

Variable-Temperature ESI-IMS-MS Analysis of Myohemerythrin Reveals Ligand Losses, Unfolding, and a Non-Native Disulfide Bond.

A. Laganowsky, D. Russell, D. Clemmer, 2019, Analytical chemistry.

Structure and mechanism of human diacylglycerol O-acyltransferase-1

H. Qian, N. Yan, A. Laganowsky, 2020, Nature.

Molecular basis for amyloid-β polymorphism

David Eisenberg, Meytal Landau, Michael R. Sawaya, 2011, Proceedings of the National Academy of Sciences.

Origin of complexity in haemoglobin evolution

Georg K. A. Hochberg, A. Laganowsky, J. Benesch, 2020, Nature.

Melting of Hemoglobin in Native Solutions as measured by IMS-MS.

A. Laganowsky, D. Russell, D. Clemmer, 2020, Analytical chemistry.

Mass spectrometry of intact membrane protein complexes

Carol V Robinson, C. Robinson, A. Laganowsky, 2013, Nature Protocols.

Structure and mechanism of a primate ferroportin

Jiemin Shen, A. Laganowsky, Z. Ren, 2020, bioRxiv.

Chapter 1 An Introduction to the Basic Principles and Concepts of Mass Spectrometry

A. Laganowsky, J. Katz, F. Halgand, 2008 .

A hydrophobic ratchet entrenches molecular complexes

Georg K. A. Hochberg, E. Marklund, A. Laganowsky, 2020, Nature.

Selective regulation of human TRAAK channels by biologically active phospholipids

A. Laganowsky, Minglei Zhao, Ming Zhou, 2020, Nature Chemical Biology.

A Conserved PLPLRT/SD Motif of STING Mediates the Recruitment and Activation of TBK1

B. Sankaran, A. Laganowsky, J. Ji, 2019, Nature.

Structural Analysis of the Effect of a Dual-FLAG Tag on Transthyretin.

David H. Russell, A. Laganowsky, Michael L. Poltash, 2020, Biochemistry.

Insight into the selectivity of Kir3.2 toward phosphatidylinositides.

A. Laganowsky, Yang Liu, Pei-Qi Qiao, 2020, Biochemistry.

Quantifying the stabilizing effects of protein–ligand interactions in the gas phase

Carol V Robinson, Timothy M Allison, Idlir Liko, 2015, Nature Communications.

Investigation of Protein-Lipid Interactions Using Native Mass Spectrometry.

A. Laganowsky, J. Patrick, Xiaowen Liang, 2021, Methods in molecular biology.

The Effect of Detergent, Temperature, and Lipid on the Oligomeric State of MscL Constructs: Insights from Mass Spectrometry.

D. Rees, C. Robinson, A. Laganowsky, 2015, Chemistry & biology.

The role of the detergent micelle in preserving the structure of membrane proteins in the gas phase.

Carol V Robinson, Timothy M Allison, Idlir Liko, 2015, Angewandte Chemie.

Collision-Induced Unfolding Studies of Proteins and Protein Complexes using Drift Tube Ion Mobility-Mass Spectrometer.

A. Laganowsky, D. Russell, Xueyun Zheng, 2020, Analytical chemistry.

First-Principles Collision Cross Section Measurements of Large Proteins and Protein Complexes.

A. Laganowsky, Michael L. Poltash, Klaudia I. Kocurek, 2020, Analytical chemistry.

Generation of Charge-Reduced Ions of Membrane Protein Complexes for Native Ion Mobility Mass Spectrometry Studies

A. Laganowsky, J. Patrick, 2019, Journal of The American Society for Mass Spectrometry.

Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding.

A. Laganowsky, V. Wysocki, D. Russell, 2021, Analytical chemistry.

The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity

Georg K. A. Hochberg, D. Eisenberg, J. Stroud, 2014, Proceedings of the National Academy of Sciences.

New insights into the metal-induced oxidative degradation pathways of transthyretin.

A. Laganowsky, Michael L. Poltash, D. Russell, 2019, Chemical communications.

Native IM-Orbitrap MS: Resolving What Was Hidden.

A. Laganowsky, Michael L. Poltash, D. Russell, 2020, Trends in analytical chemistry : TRAC.

Topological Analysis of Transthyretin Disassembly Mechanism: Surface-Induced Dissociation Reveals Hidden Reaction Pathways.

C. D. Boone, David H Russell, A. Laganowsky, 2019, Analytical chemistry.

A hydrophobic ratchet entrenches molecular complexes

Georg K. A. Hochberg, E. Marklund, A. Laganowsky, 2020, Nature.

Origin of complexity in hemoglobin evolution

Georg K. A. Hochberg, A. Laganowsky, J. Benesch, 2020, Nature.

Allosteric modulation of protein-protein interactions by individual lipid binding events

A. Laganowsky, Yang Liu, Xiao Cong, 2017, Nature Communications.

Structural basis for lipid and copper regulation of the ABC transporter MsbA

Georg K. A. Hochberg, A. Laganowsky, Minglei Zhao, 2022, bioRxiv.

Determining Membrane Protein-Lipid Binding Thermodynamics Using Native Mass Spectrometry.

A. Laganowsky, D. Russell, Xiaowen Liang, 2016, Journal of the American Chemical Society.

An approach to crystallizing proteins by metal‐mediated synthetic symmetrization

T. Yeates, M. Sawaya, A. Laganowsky, 2011, Protein science : a publication of the Protein Society.

Enhanced Characterization of Membrane Protein Complexes by Ultraviolet Photodissociation Mass Spectrometry.

A. Laganowsky, J. Brodbelt, J. Patrick, 2019, Analytical chemistry.

Probing Heterogeneous Lipid Interactions with Membrane Proteins Using Mass Spectrometry.

A. Laganowsky, J. Patrick, 2019, Methods in molecular biology.

Melting Proteins: Evidence for Multiple Stable Structures upon Thermal Denaturation of Native Ubiquitin from Ion Mobility Spectrometry-Mass Spectrometry Measurements.

A. Laganowsky, D. Russell, D. Clemmer, 2017, Journal of the American Chemical Society.

Protons Are Fast and Smart; Proteins Are Slow and Dumb: On the Relationship of Electrospray Ionization Charge States and Conformations.

A. Laganowsky, S. Valentine, D. Russell, 2021, Journal of the American Society for Mass Spectrometry.

Discovery of potent charge-reducing molecules for native ion mobility mass spectrometry studies.

A. Laganowsky, Lei Fang, D. Russell, 2020, Analytical chemistry.