C. Karger

C. K. Spindeldreier, I. Kawrakow, C. Karger, 2020, Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics.

The geometric accuracy of medical images and elastic image registration in radiation therapy

W. Schlegel, C. Karger, 2008 .

Carbon Ion Radiotherapy for Chordomas and Low-Grade Chondrosarcomas of the Skull Base

J. Debus, C. Karger, C. Thilmann, 2003, Strahlentherapie und Onkologie.

B-spline registration versus demons algorithm - a quantitative comparison of accuracy and invertibility based on artificially created test cases for the lung

M. Kessler, C. Karger, M. Hub, 2009 .

Measurement of hypoxia-related parameters in three sublines of a rat prostate carcinoma using dynamic (18)F-FMISO-Pet-Ct and quantitative histology.

Caixia Cheng, A. Dimitrakopoulou-Strauss, U. Haberkorn, 2015, American journal of nuclear medicine and molecular imaging.

Impact of Single Dose Photons and Carbon Ions on Perfusion and Vascular Permeability: A Dynamic Contrast-Enhanced MRI Pilot Study in the Anaplastic Rat Prostate Tumor R3327-AT1

C. Debus, R. Floca, J. Debus, 2019, Radiation Research.

Delayed vascular injury after single high-dose irradiation in the rat brain: histologic immunohistochemical, and angiographic studies.

J. Debus, C. Karger, W. Reith, 1999, Radiology.

Experimental determination of the effective point of measurement and the displacement correction factor for cylindrical ionization chambers in a 6 MV photon beam.

G. Hartmann, C. Karger, C. Legrand, 2012, Physics in medicine and biology.

Synergistic effect of cinacalcet and active vitamin D in a dialysis patient with secondary hyperparathyroidism

C. Karger, C. Sommerer, M. Zeier, 2010 .

Compatibility of 3D printing materials and printing techniques with PAGAT gel dosimetry

P. Mann, C. Karger, A. Runz, 2019, Physics in medicine and biology.

DCE-MRI detected vascular permeability changes in the rat spinal cord do not explain shorter latency times for paresis after carbon ions relative to photons.

C. Karger, P. Peschke, T. Welzel, 2021, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

High Doses of Photons and Carbon Ions Comparably Increase Vascular Permeability in R3327-HI Prostate Tumors: A Dynamic Contrast-Enhanced MRI Study

J. Debus, J. Peter, C. Karger, 2020, Radiation Research.

Roadmap: helium ion therapy

R. Mohan, D. Georg, M. Durante, 2022, Physics in medicine and biology.

Assessment of RBE-weighted dose models for carbon ion therapy towards modernization of clinical practice at HIT: in vitro, in vivo and in patients.

J. Debus, A. Abdollahi, C. Karger, 2020, International journal of radiation oncology, biology, physics.

Quality assurance at the heavy-ion therapy facility at GSI

G. Hartmann, C. Karger, G. Kraft, 1999, Strahlentherapie und Onkologie.

A review on reference dosimetry in radiation therapy with proton and light ion beams: Status and impact of new developments

C. Karger, J. Vedelago, O. Jäkel, 2022, Radiation Measurements.

Development of a breathing phantom for comparison of two breathing surrogates systems in 4 DCT-imaging

U. Oelfke, C. Karger, 2011 .

Simulation of hypoxia PET-tracer uptake in tumours: Dependence of clinical uptake-values on transport parameters and arterial input function.

C. Karger, A. Gago-Arias, I. Espinoza, 2020, Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics.

Carbon ion radiotherapy for pediatric patients and young adults treated for tumors of the skull base

J. Debus, C. Karger, M. Münter, 2009, Cancer.

Photon and Carbon Ion Irradiation of a Rat Prostate Carcinoma: Does a Higher Fraction Number Increase the Metastatic Rate?

J. Debus, C. Karger, P. Peschke, 2014, Radiation research.

Experimental determination of the effective point of measurement for cylindrical ionization chambers in 60Co gamma radiation

G. Hartmann, C. Karger, C. Legrand, 2012, Physics in medicine and biology.

Carbon ion radiotherapy decreases the impact of tumor heterogeneity on radiation response in experimental prostate tumors.

J. Debus, R. Mason, C. Karger, 2016, Cancer letters.

Longitudinal MRI study after carbon ion and photon irradiation: shorter latency time for myelopathy is not associated with differential morphological changes

J. Debus, C. Karger, P. Peschke, 2020, Radiation oncology.

Intrinsic and extrinsic tumor characteristics are of minor relevance for the efficacy of split-dose carbon ion irradiation in three experimental prostate tumors.

J. Debus, C. Karger, P. Peschke, 2019, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Impact of DNA Repair Kinetics and Dose Rate on RBE Predictions in the UNIVERSE

A. Abdollahi, C. Karger, H. Liew, 2022, International journal of molecular sciences.

In Vivo Validation of the BIANCA Biophysical Model: Benchmarking against Rat Spinal Cord RBE Data

C. Karger, A. Mairani, P. Sala, 2020, International journal of molecular sciences.

Fractionated carbon ion irradiations of the rat spinal cord: comparison of the relative biological effectiveness with predictions of the local effect model

J. Debus, C. Karger, P. Peschke, 2020, Radiation Oncology.

Split dose carbon ion irradiation of the rat spinal cord: Dependence of the relative biological effectiveness on dose and linear energy transfer.

J. Debus, C. Karger, P. Peschke, 2015, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Experience with carbon ion radiotherapy at GSI

J. Debus, C. Karger, O. Jäkel, 2005 .

Radiation Tolerance of the Rat Spinal Cord after Single and Split Doses of Photons and Carbon Ions1

J. Debus, C. Karger, P. Peschke, 2003, Radiation research.

Dose–Response Curves for Late Functional Changes in the Normal Rat Brain after Single Carbon-Ion Doses Evaluated by Magnetic Resonance Imaging: Influence of Follow-up Time and Calculation of Relative Biological Effectiveness

S. Heiland, G. Hartmann, J. Debus, 2002, Radiation research.

FIRST PATIENTS ’ TREATMENT AT GSI USING HEAVY-ION BEAMS

J. Debus, D. Schardt, G. Hartmann, 1998 .

A system for stereotactic irradiation and magnetic resonance evaluations in the rat brain.

G. Hartmann, W. Lorenz, C. Karger, 1995, International journal of radiation oncology, biology, physics.

Temporal lobe reactions after carbon ion radiation therapy: comparison of relative biological effectiveness-weighted tolerance doses predicted by local effect models I and IV.

C. Karger, O. Jäkel, C. Gillmann, 2014, International journal of radiation oncology, biology, physics.

[Clinical dosimetry for heavy ion therapy].

G. Hartmann, C. Karger, O. Jäkel, 2002, Zeitschrift fur medizinische Physik.

Feasibility of polymer gel-based measurements of radiation isocenter accuracy in magnetic fields

P. Mann, C. Lang, C. Karger, 2018, Physics in medicine and biology.

Biological Models in Treatment Planning

Christian P. Karger, C. Karger, 2006 .

Effectiveness of carbon ion radiotherapy in the treatment of skull-base chordomas.

Michael Scholz, Christian P Karger, Oliver Jäkel, 2007, International journal of radiation oncology, biology, physics.

Evaluation of salivary gland function after treatment of head-and-neck tumors with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy.

S. Nill, J. Debus, C. Karger, 2004, International journal of radiation oncology, biology, physics.

Current Status and New Developments in Ion Therapy

Oliver Jäkel, C. Karger, O. Jäkel, 2007, Strahlentherapie und Onkologie.

Radiation tolerance of the rat spinal cord after 6 and 18 fractions of photons and carbon ions: experimental results and clinical implications.

J. Debus, C. Karger, P. Peschke, 2006, International journal of radiation oncology, biology, physics.

Relative biological effectiveness of carbon ions for local tumor control of a radioresistant prostate carcinoma in the rat.

J. Debus, C. Karger, P. Peschke, 2011, International journal of radiation oncology, biology, physics.

Dosimetry for ion beam radiotherapy

Christian P Karger, Oliver Jäkel, Tatsuaki Kanai, 2010, Physics in medicine and biology.

Results of carbon ion radiotherapy in 152 patients.

Oliver Jäkel, Thomas Haberer, Jürgen Debus, 2004, International journal of radiation oncology, biology, physics.

Heavy Ion Therapy: Status and Perspectives

O Jäkel, J Debus, C P Karger, 2003, Technology in cancer research & treatment.

Relation between carbon ion ranges and x-ray CT numbers.

O Jäkel, C P Karger, G H Hartmann, 2001, Medical physics.

Treatment planning for heavy ion radiotherapy: clinical implementation and application.

O Jäkel, J Debus, C P Karger, 2001, Physics in medicine and biology.

Does the uncertainty in relative biological effectiveness affect patient treatment in proton therapy?

B. S. Sørensen, M. Schwarz, A. Lühr, 2021, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Determination of the proton RBE in the rat spinal cord: Is there an increase towards the end of the spread-out Bragg peak?

J. Debus, C. Karger, P. Peschke, 2018, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Ramipril reduces incidence and prolongates latency time of radiation-induced rat myelopathy after photon and carbon ion irradiation

J. Debus, C. Karger, P. Peschke, 2020, Journal of radiation research.

The history of ion beam therapy in Germany

C. Karger, G. Kraft, O. Jäkel, 2022, Zeitschrift fur medizinische Physik.

Impact of enhancements in the local effect model (LEM) on the predicted RBE-weighted target dose distribution in carbon ion therapy

M Scholz, C P Karger, M Krämer, 2012, Physics in medicine and biology.

[Late radiation changes after small volume radiosurgery of the rat brain. Measuring local cerebral blood flow and histopathological studies].

J. Debus, C. Karger, M. Münter, 2001, Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al].

Measurement of isocenter alignment accuracy and image distortion of an 0.35 T MR-Linac system

Christian P Karger, Sebastian Klüter, Armin Runz, 2019, Physics in medicine and biology.

Therapy strategies for locally advanced adenoid cystic carcinomas using modern radiation therapy techniques

J. Debus, C. Karger, M. Münter, 2005, Cancer.

Radiobiological issues in prospective carbon ion therapy trials

C. Karger, P. Fossati, N. Matsufuji, 2018, Medical physics.

Carbon ion radiation therapy for high-risk meningiomas.

A. von Deimling, J. Debus, C. Karger, 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

End-to-end test for fractionated online adaptive MR-guided radiotherapy using a deformable anthropomorphic pelvis phantom

P. Mann, C. Karger, A. Schwahofer, 2021, Physics in medicine and biology.

End-to-end test of an online adaptive treatment procedure in MR-guided radiotherapy using a phantom with anthropomorphic structures

Christian P Karger, Sebastian Klüter, Armin Runz, 2019, Physics in medicine and biology.

PAGAT gel dosimetry for everyone: gel production, measurement and evaluation

R. Floca, P. Mann, C. Karger, 2021, Biomedical physics & engineering express.

Radiation dosimetry in magnetic fields with Farmer-type ionization chambers: determination of magnetic field correction factors for different magnetic field strengths and field orientations

C P Karger, I Kawrakow, C. K. Spindeldreier, 2017, Physics in medicine and biology.

Dose-response relationship for late functional changes in the rat brain after radiosurgery evaluated by magnetic resonance imaging.

W. J. Lorenz, J. Debus, G. Hartmann, 1997, International journal of radiation oncology, biology, physics.

Stereotactic imaging for radiotherapy: accuracy of CT, MRI, PET and SPECT.

Christian P Karger, Peter Hipp, Lothar Schad, 2003, Physics in medicine and biology.

Quantification of Microglial Late Reaction to Stereotactic Irradiation of the Rat Brain Using Computer-Aided Image Analysis

J. Debus, P. Gass, C. Karger, 1999, Experimental Neurology.

Quality assurance and temporal stability of a 1.5 T MRI scanner for MR-guided Photon and Particle Therapy.

C. Karger, O. Jäkel, J. Debus, 2023, Zeitschrift fur medizinische Physik.

Molecular ultrasound imaging of early vascular response in prostate tumors irradiated with carbon ions.

Michael Scholz, Christian P Karger, Wolfhard Semmler, 2009, Neoplasia.

Carbon ion irradiation of the rat spinal cord: dependence of the relative biological effectiveness on linear energy transfer.

Michael Scholz, Christin Glowa, Christian P Karger, 2014, International journal of radiation oncology, biology, physics.

Treatment planning intercomparison for spinal chordomas using intensity-modulated photon radiation therapy (IMRT) and carbon ions.

J. Debus, C. Karger, M. Wannenmacher, 2003, Physics in medicine and biology.

Prediction of radiation-induced changes in the lung after stereotactic body radiation therapy of non-small-cell lung cancer.

W. Schlegel, J. Debus, C. Karger, 2007, International journal of radiation oncology, biology, physics.

Accuracy of device-specific 2D and 3D image distortion correction algorithms for magnetic resonance imaging of the head provided by a manufacturer

Christian P Karger, Valer Canda, Rolf Bendl, 2006, Physics in medicine and biology.

Influence of setup errors on spinal cord dose and treatment plan quality for cervical spine tumours: a phantom study for photon IMRT and heavy charged particle radiotherapy.

Christian P Karger, Oliver Jäkel, Jürgen Debus, 2003, Physics in medicine and biology.

A model to simulate the oxygen distribution in hypoxic tumors for different vascular architectures.

C. Karger, P. Peschke, I. Espinoza, 2013, Medical physics.

Quality assurance for a treatment planning system in scanned ion beam therapy.

J Rassow, O Jäkel, C P Karger, 2000, Medical physics.

Late normal tissue response in the rat spinal cord after carbon ion irradiation

J. Debus, C. Karger, P. Peschke, 2018, Radiation oncology.

The RBE in ion beam radiotherapy: In vivo studies and clinical application.

C. Karger, P. Peschke, W. Kraft-Weyrather, 2021, Zeitschrift fur medizinische Physik.

Fractionated carbon ion irradiations of the rat spinal cord: comparison of the relative biological effectiveness with predictions of the local effect model

J. Debus, C. Karger, P. Peschke, 2020, Radiation oncology.

Bolus arrival time estimation in dynamic contrast-enhanced magnetic resonance imaging of small animals based on spline models

Jörg Peter, Alina L Bendinger, Charlotte Debus, 2018, Physics in medicine and biology.

Software for quantitative analysis of radiotherapy: Overview, requirement analysis and design solutions

Lanlan Zhang, Christian Thieke, Oliver Nix, 2013, Comput. Methods Programs Biomed..

Single-cell-based computer simulation of the oxygen-dependent tumour response to irradiation

Christian P Karger, Peter Peschke, C. Karger, 2007, Physics in medicine and biology.

Dose-response curves for MRI-detected radiation-induced temporal lobe reactions in patients after proton and carbon ion therapy: Does the same RBE-weighted dose lead to the same biological effect?

A. Lomax, C. Karger, O. Jäkel, 2018, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Carbon ion radiotherapy: impact of tumor differentiation on local control in experimental prostate carcinomas

J. Debus, C. Karger, K. Kopka, 2017, Radiation oncology.

Three-dimensional accuracy and interfractional reproducibility of patient fixation and positioning using a stereotactic head mask system.

O Jäkel, C P Karger, G H Hartmann, 2001, International journal of radiation oncology, biology, physics.

Clinical evaluation of a laser surface scanning system in 120 patients for improving daily setup accuracy in fractionated radiation therapy.

Christian P Karger, Matthias Uhl, Kai Schubert, 2013, International journal of radiation oncology, biology, physics.

Quality management of medical physics issues at the German heavy ion therapy project.

O Jäkel, C P Karger, G H Hartmann, 2000, Medical physics.

A system for three-dimensional dosimetric verification of treatment plans in intensity-modulated radiotherapy with heavy ions.

O Jäkel, C P Karger, G H Hartmann, 1999, Medical physics.

Determination of Tolerance Dose Uncertainties and Optimal Design of Dose Response Experiments with Small Animal Numbers

G. Hartmann, C. Karger, 2001, Strahlentherapie und Onkologie.

A method for determining the alignment accuracy of the treatment table axis at an isocentric irradiation facility

O Jäkel, C P Karger, G H Hartmann, 2001, Physics in medicine and biology.

The relative biological effectiveness of carbon ion irradiations of the rat spinal cord increases linearly with LET up to 99 keV/μm

Michael Scholz, Christin Glowa, Jürgen Debus, 2016, Acta oncologica.

A calibration procedure for beam monitors in a scanned beam of heavy charged particles.

O Jäkel, C P Karger, G H Hartmann, 2004, Medical physics.

Effectiveness of fractionated carbon ion treatments in three rat prostate tumors differing in growth rate, differentiation and hypoxia.

J. Debus, C. Karger, P. Peschke, 2021, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Validation of 4D dose calculation using an independent motion monitoring by the calypso tracking system and 3D polymer gel dosimetry

Christian P. Karger, C. Lang, A. Runz, 2017 .

Comparison of two respiration monitoring systems for 4D imaging with a Siemens CT using a new dynamic breathing phantom

A C Vásquez, A Runz, G Echner, 2012, Physics in medicine and biology.

ESTRO ACROP: Technology for precision small animal radiotherapy research: Optimal use and challenges.

Frank Verhaegen, Christian P Karger, David Sarrut, 2017, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

A method to visualize the uncertainty of the prediction of radiobiological models.

Christian P Karger, Christian Thieke, Martina Hub, 2013, Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics.

Relative biological effectiveness of single and split helium ion doses in the rat spinal cord increases strongly with linear energy transfer.

C. Karger, P. Peschke, S. Mein, 2022, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

RBE-weighted doses in target volumes of chordoma and chondrosarcoma patients treated with carbon ion radiotherapy: Comparison of local effect models I and IV.

C. Karger, O. Jäkel, C. Gillmann, 2019, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Treatment planning for carbon ion radiotherapy in Germany: review of clinical trials and treatment planning studies.

O Jäkel, C P Karger, P Heeg, 2004, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Photoacoustic imaging to assess pixel-based sO2 distributions in experimental prostate tumors

Jörg Peter, Alina L Bendinger, Christin Glowa, 2018, Journal of biomedical optics.

Reference dosimetry in MRI-linacs: evaluation of available protocols and data to establish a Code of Practice

S. Duane, J. Wolthaus, C. Karger, 2020, Physics in medicine and biology.

Feasibility of dosimetry with optically stimulated luminescence detectors in magnetic fields

Steffen Greilich, A. Pfaffenberger, Christian P. Karger, 2017 .

Late normal tissue response in the rat spinal cord after carbon ion irradiation

J. Debus, C. Karger, P. Peschke, 2018, Radiation Oncology.

Gel dosimetry provides the optimal end-to-end quality assurance dosimetry for MR-linacs.

Habib Zaidi, Christian P Karger, Clive Baldock, 2020, Medical physics.

Flow cytometric characterization of tumor subpopulations in three sublines of the dunning R3327 rat prostate tumor model

J. Debus, C. Karger, P. Peschke, 2013, The Prostate.

Relative biological effectiveness of carbon ions in a rat prostate carcinoma in vivo: comparison of 1, 2, and 6 fractions.

J. Debus, C. Karger, P. Peschke, 2013, International journal of radiation oncology, biology, physics.

C. Karger, P. Peschke, 2017, Physics in medicine and biology.

Comments to the forum of M. Goitein.

J. Debus, C. Karger, O. Jäkel, 2004, Zeitschrift fur medizinische Physik.

Computer simulation of tumour control probabilities after irradiation for varying intrinsic radio-sensitivity using a single cell based model

C. Karger, P. Peschke, C. Harting, 2010, Acta oncologica.

Computer simulation of the radiation response of hypoxic tumours

W. Schlegel, C. Karger, 2013 .