H. Hermanns

发表

Principles of interleukin (IL)-6-type cytokine signalling and its regulation.

P. Heinrich, I. Behrmann, S. Haan, 2003, The Biochemical journal.

Deficiency of HIF1&agr; in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice

Jaroslav Pelisek, Miriam Koch, Alma Zernecke, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases

H. Hermanns, J. Scheller, D. Floss, 2016, Molecular biology of the cell.

CLP 36 is a Negative Regulator of GPVI Signaling in Platelets

Nagy, Shuchi Gupta, H. Hermanns, 2012 .

CLP36 Is a Negative Regulator of Glycoprotein VI Signaling in Platelets

Shuchi Gupta, H. Hermanns, A. Sickmann, 2012, Circulation research.

Induction of CCL13 expression in synovial fibroblasts highlights a significant role of oncostatin M in rheumatoid arthritis.

P. Heinrich, H. Hermanns, T. Pap, 2009, Arthritis and rheumatism.

Farnesoid X receptor-dependent and -independent pathways mediate the transcriptional control of human fibroblast growth factor 19 by vitamin A.

H. Hermanns, J. Schmitt, D. Jahn, 2016, Biochimica et biophysica acta.

Mechanisms of enterohepatic fibroblast growth factor 15/19 signaling in health and disease.

H. Hermanns, M. Rau, D. Jahn, 2015, Cytokine & growth factor reviews.

Non-Alcoholic Steatohepatitis: From Pathophysiology to Novel Therapies

H. Hermanns, J. Wohlfahrt, M. Rau, 2016, Digestive Diseases.

Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function.

James A. Hutchinson, H. Hermanns, M. Huber, 2017, Blood advances.

IFN-gamma-induced PD-L1 expression in melanoma depends on p53 expression

S. Meierjohann, H. Hermanns, M. Goebeler, 2019, Journal of Experimental & Clinical Cancer Research.

The Crystal Structure of the Protein-Disulfide Isomerase Family Member ERp27 Provides Insights into Its Substrate Binding Capabilities*

H. Hermanns, H. Schindelin, J. Kuper, 2012, The Journal of Biological Chemistry.

Animal models of NAFLD from a hepatologist's point of view.

H. Hermanns, D. Jahn, A. Geier, 2019, Biochimica et biophysica acta. Molecular basis of disease.

IL-4 analogues with site-specific chemical modification at position 121 inhibit IL-4 and IL-13 biological activities.

H. Hermanns, W. Sebald, W. Schmitz, 2014, Bioconjugate chemistry.

Intestinal vitamin D receptor modulates lipid metabolism, adipose tissue inflammation and liver steatosis in obese mice.

H. Hermanns, J. Schmitt, D. Jahn, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Oncostatin M-Induced and Constitutive Activation of the JAK2/STAT5/CIS Pathway Suppresses CCL1, but Not CCL7 and CCL8, Chemokine Expression1

P. Heinrich, H. Hermanns, J. Tuckermann, 2008, The Journal of Immunology.

Growth Factor Receptor–Bound Protein 2 Contributes to (Hem)Immunoreceptor Tyrosine-Based Activation Motif–Mediated Signaling in Platelets

H. Hermanns, S. Watson, B. Nieswandt, 2014, Circulation research.

Grb2 Contributes to (hem)ITAM-Mediated Signaling in Platelets

H. Hermanns, B. Nieswandt, S. Dütting, 2013 .

Signal Attenuation M: Structural Receptor Requirements for Leukemia-Inhibitory Factor, and Oncostatin Signal Transduction of IL-6,

P. Heinrich, I. Behrmann, H. Hermanns, 2000 .

Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice

K. Lesch, H. Hermanns, G. Stoll, 2016, PloS one.

Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis.

A. Bosio, T. Bieber, P. Heinrich, 2006, The Journal of allergy and clinical immunology.

Mapping of a Region within the N Terminus of Jak1 Involved in Cytokine Receptor Interaction*

I. Kerr, P. Heinrich, I. Behrmann, 2001, The Journal of Biological Chemistry.

IL-31 receptor alpha expression in epidermal keratinocytes is modulated by cell differentiation and interferon gamma.

P. Heinrich, H. Hermanns, H. Merk, 2009, The Journal of investigative dermatology.

TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice.

T. Gudermann, T. Dandekar, P. Noy, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Flt3L, LIF, and IL‐10 combination promotes the selective in vitro development of ESAMlow cDC2B from murine bone marrow

A. Kerstan, H. Hermanns, H. Raifer, 2022, European Journal of Immunology.

The Jak1 SH2 Domain Does Not Fulfill a Classical SH2 Function in Jak/STAT Signaling but Plays a Structural Role for Receptor Interaction and Up-regulation of Receptor Surface Expression*

P. Heinrich, I. Behrmann, S. Haan, 2005, Journal of Biological Chemistry.

Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases

P. Nurden, H. Hermanns, B. Nieswandt, 2019, Scientific Reports.

Non-redundant Signal Transduction of Interleukin-6-type Cytokines

P. Heinrich, I. Behrmann, H. Hermanns, 2000, The Journal of Biological Chemistry.

Oncostatin M and interleukin-31: Cytokines, receptors, signal transduction and physiology.

H. Hermanns, 2015, Cytokine & growth factor reviews.

Characterization of the Rat Oncostatin M Receptor Complex Which Resembles the Human, but Differs from the Murine Cytokine Receptor

H. Hermanns, J. Grötzinger, J. Drechsler, 2012, PloS one.

Box 2 Region of the Oncostatin M Receptor Determines Specificity for Recruitment of Janus Kinases and STAT5 Activation*

C. Evers, P. Heinrich, H. Hermanns, 2008, Journal of Biological Chemistry.

Oncostatin M Receptor-mediated Signal Transduction Is Negatively Regulated by SOCS3 through a Receptor Tyrosine-independent Mechanism*

P. Heinrich, H. Hermanns, F. Schaper, 2006, Journal of Biological Chemistry.

Interleukin-6-type cytokines upregulate expression of multidrug resistance-associated proteins in NHEK and dermal fibroblasts.

P. Heinrich, H. Hermanns, H. Merk, 2005, The Journal of investigative dermatology.

Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Is Marked by a Higher Frequency of Th17 Cells in the Liver and an Increased Th17/Resting Regulatory T Cell Ratio in Peripheral Blood and in the Liver

H. Hermanns, M. Rau, A. Geier, 2016, The Journal of Immunology.

RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.

T. Dandekar, M. Sauer, H. Hermanns, 2021, Cell reports.

Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease

T. Dandekar, P. Rosenstiel, H. Hermanns, 2018, United European gastroenterology journal.

Endocytosis of pro-inflammatory cytokine receptors and its relevance for signal transduction

H. Hermanns, J. Wohlfahrt, D. Jahn, 2016, Biological chemistry.

A single amino acid substitution (Trp(666)-->Ala) in the interbox1/2 region of the interleukin-6 signal transducer gp130 abrogates binding of JAK1, and dominantly impairs signal transduction.

P. Heinrich, I. Behrmann, H. Hermanns, 2000, The Biochemical journal.

REVIEW ARTICLE Principles of interleukin (IL)-6-type cytokine signalling and its regulation 1

P. Heinrich, S. Haan, H. Hermanns, 2003 .

The PD-L 1-and IL 6-mediated dampening of the IL 27 / STAT 1 anticancer responses are prevented by α-PD-L 1 or α-IL 6 antibodies

A. Ginolhac, I. Behrmann, S. Haan, 2018 .

Signal Transduction of IL-6, Leukemia-Inhibitory Factor, and Oncostatin M: Structural Receptor Requirements for Signal Attenuation1

P. Heinrich, I. Behrmann, H. Hermanns, 2000, The Journal of Immunology.

Interferon Alpha Signalling and Its Relevance for the Upregulatory Effect of Transporter Proteins Associated with Antigen Processing (TAP) in Patients with Malignant Melanoma

R. Tampé, H. Hermanns, H. Merk, 2016, PloS one.

Plasticity and cross-talk of interleukin 6-type cytokines.

H. Hermanns, G. Müller-Newen, F. Schaper, 2012, Cytokine & growth factor reviews.

Beneficial Effects of Vitamin D Treatment in an Obese Mouse Model of Non-Alcoholic Steatohepatitis

H. Hermanns, K. Lenaerts, I. Bergheim, 2017, Zeitschrift für Gastroenterologie.

Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation

M. Gaestel, P. Heinrich, I. Behrmann, 2010, Journal of Cell Science.

Complement 1q/Tumor Necrosis Factor-Related Proteins (CTRPs): Structure, Receptors and Signaling

H. Hermanns, H. Wajant, K. Lorenz, 2023, Biomedicines.

Oncostatin M-induced activation of stress-activated MAP kinases depends on tyrosine 861 in the OSM receptor and requires Jak1 but not Src kinases.

P. Heinrich, H. Hermanns, B. Lippok, 2006, Cellular signalling.

Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130.

J. Tavernier, P. Heinrich, I. Behrmann, 1999, Journal of immunology.

Complexes with Glycoprotein 130 Signal Transduction in Heterodimeric Receptor and Oncostatin M Receptor to Contributions of Leukemia Inhibitory Factor

J. Tavernier, P. Heinrich, I. Behrmann, 1999 .

Characterization of the Signaling Capacities of the Novel gp130-like Cytokine Receptor*

P. Heinrich, H. Hermanns, S. Pflanz, 2004, Journal of Biological Chemistry.

The PD‐L1‐ and IL6‐mediated dampening of the IL27/STAT1 anticancer responses are prevented by α‐PD‐L1 or α‐IL6 antibodies

A. Ginolhac, I. Behrmann, S. Haan, 2018, Journal of leukocyte biology.

Oncostatin M induces RIG‐I and MDA5 expression and enhances the double‐stranded RNA response in fibroblasts

H. Hermanns, C. Mais, A. Costa-Pereira, 2017, Journal of cellular and molecular medicine.

Signaling through a Mutant IFN-γ Receptor

I. Kerr, P. Heinrich, H. Hermanns, 2005, The Journal of Immunology.

A Single STAT Recruitment Module in a Chimeric Cytokine Receptor Complex Is Sufficient for STAT Activation*

Jan Tavernier, Peter C. Heinrich, J. Tavernier, 1997, The Journal of Biological Chemistry.

Structural Bases of Receptor-JAK-STAT Interactions

P. Heinrich, I. Behrmann, S. Haan, 2003 .

Orientational Constraints of the gp130 Intracellular Juxtamembrane Domain for Signaling*

P. Heinrich, I. Behrmann, H. Hermanns, 2002, The Journal of Biological Chemistry.

Novel Role of Janus Kinase 1 in the Regulation of Oncostatin M Receptor Surface Expression*

P. Heinrich, I. Behrmann, H. Hermanns, 2002, The Journal of Biological Chemistry.

Cutting Edge: Imbalanced Cation Homeostasis in MAGT1-Deficient B Cells Dysregulates B Cell Development and Signaling in Mice

T. Gudermann, A. Zernecke, H. Hermanns, 2018, The Journal of Immunology.

Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases

P. Nurden, H. Hermanns, B. Nieswandt, 2019, Scientific Reports.

Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines.

A. Ginolhac, I. Behrmann, S. Haan, 2017, Biochimica et biophysica acta. Molecular cell research.

Bow to your partner for signaling

P. Heinrich, S. Haan, H. Hermanns, 2005, Nature Structural &Molecular Biology.

Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to thrombin and accelerates thrombus formation in vivo

H. Hermanns, B. Nieswandt, M. Bösl, 2023, Frontiers in Immunology.

Impact of Liver Inflammation on Bile Acid Side Chain Shortening and Amidation

R. Bataller, H. Hermanns, M. Ávila, 2022, Cells.

Orai1‐induced store‐operated Ca2+ entry enhances phospholipase activity and modulates canonical transient receptor potential channel 6 function in murine platelets

H. Hermanns, B. Nieswandt, S. Gambaryan, 2014, Journal of thrombosis and haemostasis : JTH.

The tyrosine 974 within the LIF-R-chain of the gp130/LIF-R heteromeric receptor complex mediates negative regulation of LIF signalling.

J. Schneider-Mergener, P. Heinrich, H. Hermanns, 2005, Cellular signalling.

Control of gp130 expression by the mitogen-activated protein kinase ERK2

H. Hermanns, M. Seckl, A. Costa-Pereira, 2014, Oncogene.

JAK/STAT signaling in cancer

P. Heinrich, S. Haan, H. Hermanns, 2006 .

Principles of interleukin (IL)-6-type cytokine signalling and its regulation.

P. Heinrich, I. Behrmann, S. Haan, 2003, The Biochemical journal.

Mechanisms of enterohepatic fibroblast growth factor 15/19 signaling in health and disease.

H. Hermanns, M. Rau, D. Jahn, 2015, Cytokine & growth factor reviews.

A key role for platelet GPVI in neutrophil recruitment, migration and NETosis in the early stages of acute lung injury.

H. Hermanns, A. Zarbock, B. Nieswandt, 2023, Blood.

Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines.

A. Ginolhac, I. Behrmann, S. Haan, 2017, Biochimica et biophysica acta. Molecular cell research.

Deficiency of HIF1&agr; in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice

M. Daemen, A. Zernecke, H. Hermanns, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Oncostatin M-induced and constitutive activation of the JAK2/STAT5/CIS pathway suppresses CCL1, but not CCL7 and CCL8 chemokine expression

H. Hermanns, C. Hintzen, C. Haan, 2009, Cell Communication and Signaling.

Oncostatin M-Induced and Constitutive Activation of the JAK2/STAT5/CIS Pathway Suppresses CCL1, but Not CCL7 and CCL8, Chemokine Expression1

H. Hermanns, J. Tuckermann, C. Hintzen, 2008, The Journal of Immunology.

Interleukin‐6: The dark side of liver regeneration in chronic liver disease

H. Hermanns, D. Jahn, A. Geier, 2017, Hepatology.