K. Luettich

发表

Variability of antioxidant-related gene expression in the airway epithelium of cigarette smokers.

A. Heguy, R. Crystal, D. Flieder, 2003, American journal of respiratory cell and molecular biology.

Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

Manuel C. Peitsch, Kim Ekroos, Julia Hoeng, 2016, International journal of molecular sciences.

Retraction: TGFβ1 activates c-Jun and Erk1 via aVβ6 integrin

K. Luettich, C. Schmidt, 2004, Molecular Cancer.

Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects.

M. Peitsch, A. Sewer, K. Luettich, 2015, Journal of proteomics.

Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract

M. Peitsch, A. Sewer, K. Luettich, 2019, Front. Genet..

How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models.

Rémi H. J. Dulize, M. Peitsch, A. Sewer, 2019, ALTEX.

Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke

M. Peitsch, K. Luettich, J. Hoeng, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

A. Heguy, R. Crystal, B. Harvey, 2005, Infection and Immunity.

The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product.

Rémi H. J. Dulize, M. Peitsch, A. Sewer, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium

M. Peitsch, A. Sewer, K. Luettich, 2017, Clinical medicine insights. Circulatory, respiratory and pulmonary medicine.

A 6-month systems toxicology inhalation study in ApoE-/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared to cigarette smoke.

M. Peitsch, Ashutosh Kumar, A. Sewer, 2020, American journal of physiology. Heart and circulatory physiology.

An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure

K. Luettich, Monita Sharma, D. Breheny, 2021, Frontiers in Toxicology.

P 8 . 8 Flavonoid-induced changes in oxygen consumption and mitochondrial membrane potential in isolated endothelial mitochondria

K. Luettich, J. Hoeng, Aleksandra Wojtala, 2018 .

Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events

Rex E FitzGerald, U. Vogel, T. Gant, 2022, Frontiers in Toxicology.

In Vitro High-Content Imaging-Based Phenotypic Analysis of Bronchial 3D Organotypic Air–Liquid Interface Cultures

M. Peitsch, K. Luettich, J. Hoeng, 2020, SLAS technology.

A 6-month inhalation toxicology study in Apoe−/− mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract

John H. Miller, Rémi H. J. Dulize, M. Peitsch, 2021, Archives of Toxicology.

Comparison of the basic morphology and function of 3D lung epithelial cultures derived from several donors

M. Peitsch, K. Luettich, J. Hoeng, 2020, Current research in toxicology.

Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes.

M. Peitsch, A. Sewer, K. Luettich, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Mitochondria as a possible target for nicotine action

M. Peitsch, K. Luettich, J. Hoeng, 2019, Journal of Bioenergetics and Biomembranes.

Epidermal growth factor receptor gene and c‐erbB‐2 gene amplification in ovarian cyst fluid

K. Luettich, T. Reimer, B. Gerber, 1996, Obstetrics and gynecology.

Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5‐week study in A/J mice

M. Peitsch, K. Luettich, J. Hoeng, 2022, Journal of applied toxicology : JAT.

Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies

U. Marx, K. Luettich, J. Hoeng, 2020, Scientific Reports.

Neonatal administration of idiotype or antiidiotype primes for protection against Escherichia coli K13 infection in mice

M. Peitsch, A. Sewer, K. Luettich, 1984, The Journal of experimental medicine.

Development of an Advanced Multicellular Intestinal Model for Assessing Immunomodulatory Properties of Anti-Inflammatory Compounds

M. Peitsch, K. Luettich, J. Hoeng, 2021, Frontiers in Pharmacology.

Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data

Rémi H. J. Dulize, M. Peitsch, K. Luettich, 2021, Frontiers in Toxicology.

Effects of cigarette smoke exposure on a mouse model of multiple sclerosis

M. Peitsch, K. Luettich, J. Hoeng, 2022, Toxicology reports.

Monoallelic up-regulation of the imprinted H19 gene in airway epithelium of phenotypically normal cigarette smokers.

A. Heguy, R. Crystal, N. Hackett, 2003, Cancer research.

Residual Risk of Nicotine

M. Peitsch, K. Luettich, J. Szostak, 2021 .

Assessment of ENDPs in Animal Models of Disease

M. Peitsch, K. Luettich, J. Hoeng, 2021 .

MicroRNAs as potential biomarkers of smoking-related diseases.

K. Luettich, Anisha Banerjee, 2012, Biomarkers in medicine.

Fetal DNA in Maternal Circulation of First‐Trimester Spontaneous Abortions

K. Luettich, J. O'Leary, M. Ring, 2001, Obstetrics and gynecology.

Estradiol, gonadotropins, and tumor markers in ovarian cyst fluid

K. Luettich, T. Reimer, B. Gerber, 1997, Acta obstetricia et gynecologica Scandinavica.

Trans-splicing repair of CD40 ligand deficiency results in naturally regulated correction of a mouse model of hyper-IgM X-linked immunodeficiency

R. Crystal, K. Luettich, M. Tahara, 2004, Nature Medicine.

Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective

K. Luettich, F. Lowe, E. Gregg, 2013, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice

M. Peitsch, A. Sewer, K. Luettich, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Improved in situ detection method for telomeric tandem repeats in metaphase spreads and interphase nuclei

K. Luettich, M. O’Donovan, O. Sheils, 2000, Molecular pathology : MP.

Polymerase chain reaction and its applications

K. Luettich, N. Bermingham, 2003 .

MINI-SYMPOSIUM: ADVANCES IN LABORATORY PRACTICE

K. Luettich, K. Luettich, 2003 .

Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking

A. Heguy, R. Crystal, N. Hackett, 2006, Journal of Molecular Medicine.

Physiological and biological characterization of smokers with and without COPD

M. Peitsch, K. Luettich, J. Hoeng, 2018, F1000Research.

Data of physiological measurements and quality of life in subjects with mild to moderate COPD compared to asymptomatic current smokers, former smokers and never-smokers.

M. Peitsch, K. Luettich, J. Hoeng, 2017, F1000Research.

Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity.

David Allen, Pilar Prieto, Alicia Paini, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

A lung/liver-on-a-chip platform for acute and chronic toxicity studies.

Julia Hoeng, Manuel C Peitsch, Diego Marescotti, 2018, Lab on a chip.

Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies

U. Marx, K. Luettich, J. Hoeng, 2020, Scientific Reports.

Organs-on-a-chip

Manuel C. Peitsch, Julia Hoeng, Karsta Luettich, 2017 .

Mitochondrial Network and Biogenesis in Response to Short and Long-Term Exposure of Human BEAS-2B Cells to Aerosol Extracts from the Tobacco Heating System 2.2.

M. Peitsch, K. Luettich, J. Hoeng, 2020, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model

M. Peitsch, A. Sewer, K. Luettich, 2014, Interdisciplinary toxicology.

TGFβ1 activates c-Jun and Erk1 via αVβ6 integrin

Christian Schmidt, Karsta Luettich, K. Luettich, 2003, Molecular Cancer.

First anniversary of Molecular Cancer: achievements and future goals

K. Luettich, C. Schmidt, G. Sclabas, 2003, Molecular Cancer.

Analysis of fetal DNA in the maternal venous blood for abnormalities of chromosomes 13, 16, 18 and 21 in first-trimester spontaneous miscarriage

K. Luettich, J. O'Leary, M. Ring, 2003, Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology.

The Adverse Outcome Pathway for Oxidative Stress-Mediated EGFR Activation Leading to Decreased Lung Function

K. Luettich, J. Hoeng, M. Talikka, 2017 .

A lung/liver-on-a-chip platform for acute and chronic toxicity studies.

M. Peitsch, K. Luettich, J. Hoeng, 2018, Lab on a chip.

Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity.

Daniel M. Wilson, G. Patlewicz, W. Casey, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking

A. Heguy, R. Crystal, N. Hackett, 2006, Journal of Molecular Medicine.

Molecular Cancer Tgfβ 1 Activates C-jun and Erk1 via Α V Β 6 Integrin

K. Luettich, C. Schmidt, 2022 .