D. Lewis

D. Lewis, A. Cohen, Li Chen, 2006, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Impaired Accumulation and Function of Memory CD4 T Cells in Human IL-12 Receptor β1 Deficiency1

D. Lewis, W. Tu, Andrea M. Enright, 2003, The Journal of Immunology.

Newborn immunology: relevance to the clinician.

E. Stiehm, D. Lewis, J. Gern, 2006, Current problems in pediatric and adolescent health care.

Chapter 153 – Host Defense Mechanisms Against Viruses

D. Lewis, D. Lewis, 2004 .

Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells

D. Liggitt, K. Dabbagh, D. Lewis, 2004, Nature Immunology.

Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells.

Y. Lau, D. Lewis, P. Schneider, 2008, Blood.

Paraneoplastic and Therapy-Related Immune Complications in Thymic Malignancies

W. Robinson, D. Lewis, T. Katsumoto, 2019, Current Treatment Options in Oncology.

neutrophil NADPH oxidase activity and selective defects in phox autosomal recessive mutations in p 40 A new genetic subgroup of chronic granulomatous disease with

D. Lewis, M. Dinauer, S. Meroueh, 2009 .

Reduced elastogenesis: a clue to the arteriosclerosis and emphysematous changes in Schimke immuno-osseous dysplasia?

J. Charrow, C. Boerkoel, D. Lewis, 2012, Orphanet Journal of Rare Diseases.

Asymmetric Dimethylarginine and Cardiac Allograft Vasculopathy Progression: Modulation by Sirolimus

H. Valantine, J. Cooke, L. Potena, 2008, Transplantation.

Human CD8+ Regulatory T Cells Inhibit GVHD and Preserve General Immunity in Humanized Mice

Y. Lau, D. Lewis, Zheng Xiang, 2013, Science Translational Medicine.

Inhibitor vCCI Poxvirus-Derived Pan-CC-Chemokine Hyperreactivity and Inflammation by the Local Blockade of Allergic Airway

K. Dabbagh, D. Lewis, W. Lamm, 2000 .

A Case Report of Hypoglycemia and Hypogammaglobulinemia: DAVID Syndrome in a Patient With a Novel NFKB2 Mutation

M. Snyder, Shannon Rego, A. Hoffman, 2017, The Journal of clinical endocrinology and metabolism.

Activated T Cells Expression by Increasing Nuclear Factor of T Cell Priming Enhances IL-4 Gene

D. Lewis, R. Cron, M. Brunvand, 1998 .

Interleukin 4 expressed in situ selectively alters thymocyte development

R. Perlmutter, D. Liggitt, D. Lewis, 1991, The Journal of experimental medicine.

Jian Zheng Immunity in Humanized Mice Regulatory T Cells Inhibit GVHD and Preserve General + Human CD 8

Ming Liu, Y. Lau, D. Lewis, 2013 .

Efficient Induction and Expansion of Human Alloantigen-Specific CD8 Regulatory T Cells from Naive Precursors by CD40-Activated B Cells1

Y. Lau, D. Lewis, W. Tu, 2009, The Journal of Immunology.

Allergy immunotherapy and inhibition of Th2 immune responses: a sufficient strategy?

D. Lewis, 2002, Current opinion in immunology.

Hypomethylation of the interferon‐γ gene correlates with its expression by primary T‐lineage cells

D. Lewis, A. Melvin, S. Bort, 1995 .

The Importance o f Leukotrienes in Airway Inf lammat ion in a Mouse Model o f As thma

E. Chi, D. Lewis, R. Albert, 2003 .

32 – Development of the fetal and neonatal immune system

D. Lewis, 2008 .

Development of Th2 Immune Responses: Toll-Like Receptor 4 Is Required for Optimal

K. Dabbagh, D. Lewis, M. Dahl, 2002 .

Diminished expression of CD40 ligand by activated neonatal T cells.

H. Ochs, D. Lewis, A. Aruffo, 1995, The Journal of clinical investigation.

Newborn screening for severe combined immunodeficiency and T-cell lymphopenia in California: results of the first 2 years.

J. Puck, J. Church, D. Lewis, 2013, The Journal of allergy and clinical immunology.

Respiratory Infection with Influenza A Virus Interferes with the Induction of Tolerance to Aeroallergens1

K. Dabbagh, D. Lewis, D. Umetsu, 2000, The Journal of Immunology.

Structure and expression of lck transcripts in human lymphoid cells.

R. Perlmutter, S. Ziegler, J. Marth, 1988, Journal of cellular biochemistry.

Cationic liposome-DNA complexes (CLDC) adjuvant enhances the immunogenicity and cross-protective efficacy of a pre-pandemic influenza A H5N1 vaccine in mice.

T. Monath, D. Lewis, F. Liu, 2012, Vaccine.

Chemotactic responses of IL-4-, IL-10-, and IFN-γ-producing CD4+ T cells depend on tissue origin and microbial stimulus

D. Lewis, A. Hamann, D. Campbell, 2006, The Journal of Immunology.

Chemotactic Responses of IL-4-, IL-10-, and IFN-γ-Producing CD4+ T Cells Depend on Tissue Origin and Microbial Stimulus1

D. Lewis, A. Hamann, D. Campbell, 2006, The Journal of Immunology.

Simple febrile seizures: do polymorphisms of the interleukin 1 gene cluster simplify our understanding?

D. Lewis, 2002, Archives of pediatrics & adolescent medicine.

Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response.

E. Chi, W. Henderson, D. Lewis, 1997, American journal of respiratory and critical care medicine.

Severe autoinflammation in 4 patients with C-terminal variants in cell division control protein 42 homolog (CDC42) successfully treated with IL-1 β inhibition

D. Lewis, R. Goldbach-Mansky, R. Bacchetta, 2021 .

Cationic lipid/DNA complexes (JVRS-100) combined with influenza vaccine (Fluzone) increases antibody response, cellular immunity, and antigenically drifted protection.

Christopher J. Miller, David K. Hong, L. Fritts, 2009, Vaccine.

Beta 2-microglobulin-dependent T cells are dispensable for allergen- induced T helper 2 responses

K. Rogers, D. Lewis, Y. Zhang, 1996, The Journal of experimental medicine.

Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies.

D. Lewis, C. Wilson, S. Dower, 1986, The Journal of clinical investigation.

Immunocompetent Young Children Cell Immunity to Cytomegalovirus in T + Persistent and Selective Deficiency of CD4

H. Maecker, D. Lewis, G. Kemble, 2004 .

Cellular and molecular mechanisms for reduced interleukin 4 and interferon-gamma production by neonatal T cells.

D. Lewis, Christopher B Wilson, C. Wilson, 1991, The Journal of clinical investigation.

Toll-like receptors and T-helper-1/T-helper-2 responses

K. Dabbagh, D. Lewis, D. Lewis, 2003, Current opinion in infectious diseases.

Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro

Lei S. Qi, A. Barron, D. Lewis, 2022, Nature Communications.

Durable multitransgene expression in vivo using systemic, nonviral DNA delivery

Y. Liu, D. Liggitt, D. Lewis, 2019, Science Advances.

Reduced interferon-gamma mRNA levels in human neonates. Evidence for an intrinsic T cell deficiency independent of other genes involved in T cell activation

D. Lewis, C. Wilson, A. Larsen, 1986, The Journal of experimental medicine.

Single-cell Transcriptomics Reveal Different Maturation Stages and Sublineages Commitment of Human Thymic Invariant Natural Killer T cells

D. Lewis, R. Negrin, J. Baker, 2022, bioRxiv.

Allergic Diseases and Immune-Mediated Food Disorders in Pediatric Acute-Onset Neuropsychiatric Syndrome.

J. Frankovich, D. Lewis, Talia Mahony, 2018, Pediatric allergy, immunology, and pulmonology.

Lack of IL7Rα expression in T cells is a hallmark of T-cell immunodeficiency in Schimke immuno-osseous dysplasia (SIOD).

C. Boerkoel, D. Lewis, A. Baradaran‐Heravi, 2015, Clinical immunology.

Dental Abnormalities in Schimke Immuno-osseous Dysplasia

J. Charrow, C. Boerkoel, D. Lewis, 2012, Journal of dental research.

The ratio of circulating regulatory cluster of differentiation 4 T cells to endothelial progenitor cells predicts clinically significant acute rejection after heart transplantation.

K. Khush, D. Lewis, D. Choi, 2017, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

The Human gp39 Promoter TWO DISTINCT NUCLEAR FACTORS OF ACTIVATED T CELL PROTEIN-BINDING ELEMENTS CONTRIBUTE INDEPENDENTLY TO TRANSCRIPTIONAL ACTIVATION*

D. Lewis, L. Schubert, R. Cron, 1995 .

Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype.

M. Snyder, D. Lewis, C. Stratakis, 2017, Blood.

Retinoic Acid Hypersensitivity Promotes

Kirkman, D. Lewis, C. Weaver, 2013 .

Regulation of pp56lck during T‐cell activation: functional implications for the src‐like protein tyrosine kinases.

E. Krebs, R. Perlmutter, J. Marth, 1987, The EMBO journal.

Increased double-negative ab+ T cells reveal adultonset autoimmune lymphoproliferative syndrome in a patient with IgG4-related disease

Y. Natkunam, R. Advani, D. Lewis, 2021, Haematologica.

Developmental regulation of lck gene expression in T lymphocytes

K. M. Abraham, R. Perlmutter, S. Ziegler, 1991, The Journal of experimental medicine.

Regulation of immunoglobulin (Ig)E synthesis in the hyper-IgE syndrome.

R. Geha, C. Cunningham-Rundles, D. Lewis, 1990, The Journal of clinical investigation.

Disseminated Pneumocystis jirovecii Infection with Osteomyelitis in a Patient with CTLA-4 Haploinsufficiency

C. Kunder, D. Lewis, G. Uzel, 2020, Journal of Clinical Immunology.

Adult-onset presentations of genetic immunodeficiencies: genes can throw slow curves

D. Lewis, K. S. Nelson, D. Lewis, 2010, Current opinion in infectious diseases.

Basis and implications of selectively diminished cytokine production in neonatal susceptibility to infection.

D. Lewis, Christopher B Wilson, C. Wilson, 1990, Reviews of infectious diseases.

Diminished expression of CD40 ligand may contribute to the defective humoral immunity in patients with MHC class II deficiency

H. Ochs, D. Lewis, A. Aruffo, 1998, European journal of immunology.

Focus on FOCIS: the continuing diagnostic challenge of autosomal recessive chronic granulomatous disease.

David K. Hong, D. Lewis, P. Heyworth, 2008, Clinical immunology.

Regulation of Immunoglobulin (1g)E Synthesis in the Hyper-IgE Syndrome

R. Geha, C. Cunningham-Rundles, D. Lewis, 2022 .

Infectious Complications of Cell-Mediated Immunity Other Than AIDS

D. Lewis, D. Lewis, 2018 .

Lymphokine regulation and the role of abnormal regulation in immunodeficiency.

D. Lewis, C. Wilson, A. Melvin, 1993, Clinical immunology and immunopathology.

COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives

D. Lewis, Yaling Han, Joseph C. Wu, 2020, Nature Reviews Cardiology.

Decreased CD154 expression by neonatal CD4+ T cells is due to limitations in both proximal and distal events of T cell activation.

K. Dabbagh, D. Lewis, R. Cron, 2003, International immunology.

Decreased CD 154 expression by neonatal CD 4 + T cells is due to limitations in both proximal and distal events of T cell activation

K. Dabbagh, D. Lewis, R. Cron, 2003 .

Treatment of CGD-associated Colitis with the IL-23 Blocker Ustekinumab

D. Lewis, M. Butte, K. Park, 2016, Journal of Clinical Immunology.

Revisiting Human IL-12R&bgr;1 Deficiency: A Survey of 141 Patients From 30 Countries

Smita Y. Patel, A. Al-ghonaium, Sami Al-Hajjar, 2010, Medicine.

T-Cell Immunity to Subclinical Cytomegalovirus Infection Reduces Cardiac Allograft Disease

H. Valantine, J. Cooke, L. Potena, 2006, Circulation.

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity.

Xing Jun Li, Samy O Meroueh, Iwona Wrobel, 2009, Blood.

Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice

H. D. Liggitt, S. Ziegler, D. Lewis, 2005, Nature Immunology.

Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin

R. Perlmutter, S. Ziegler, J. Marth, 1987, Molecular and cellular biology.

Immunology of the Fetus and Newborn

O. Levy, D. Lewis, J. Weitkamp, 2018 .

CELLULAR IMMUNITY OF THE HUMAN FETUS AND NEONATE

D. Lewis, D. Lewis, 1998 .

The preoperative liver scan and surgical decision-making in patients with colorectal cancer.

D. Lewis, R. Folse, J. Oren, 1986, American journal of surgery.

Severe autoinflammation in four patients with C-terminal variants in CDC42 successfully treated with IL-1β inhibition.

D. Lewis, K. Jagadeesh, R. Laxer, 2019, The Journal of allergy and clinical immunology.

Lymphocyte activation provokes modification of a lymphocyte-specific protein tyrosine kinase (p56lck).

R. Perlmutter, M. Cooke, J. Marth, 1989, Journal of immunology.

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

Ash A. Alizadeh, R. Tibshirani, D. Botstein, 2000, Nature.

Deep single-cell profiling of the systemic immune response to pregnancy Twenty-one pregnant women receiving routine antepartum care at

R. Tibshirani, G. Nolan, G. Shaw, 2017 .

Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression.

Yan Huang, Thomas Lücke, Joanna Lubieniecka, 2012, Human molecular genetics.

ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner

Y. Lau, D. Lewis, Zheng Xiang, 2013, PloS one.

A T Cell-specific Enhancer of the Human CD40 Ligand Gene*

Li-Sheng Lu, D. Lewis, L. Schubert, 2002, The Journal of Biological Chemistry.

Toll-Like Receptor 4 Is Required for Optimal Development of Th2 Immune Responses: Role of Dendritic Cells1

K. Dabbagh, D. Lewis, M. Dahl, 2002, The Journal of Immunology.

Dendritic Cells RoleDevelopment of Th 2 Immune Responses : Toll-Like Receptor 4 Is Required for Optimal

K. Dabbagh, D. Lewis, M. Dahl, 2002 .

Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza

Lei S. Qi, D. Endy, N. Heaton, 2020, Cell.

Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy

Bruno Agard, Robert Tibshirani, Nima Aghaeepour, 2018, Bioinform..

Maternal T-cell engraftment associated with severe hemophagocytosis of the bone marrow in untreated X-linked severe combined immunodeficiency.

D. Lewis, T. George, C. Dvorak, 2008, Journal of pediatric hematology/oncology.

Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31.

M. Lovett, J. Burr, D. Lewis, 1996, Blood.

Longitudinal Kinetics of Cytomegalovirus-Specific T-Cell Immunity and Viral Replication in Infants With Congenital Cytomegalovirus Infection.

T. Slifer, D. Lewis, C. Dekker, 2016, Journal of the Pediatric Infectious Diseases Society.

CROSS-REACTIVE NEUTRALIZING ANTIBODY AGAINST PANDEMIC 2009 H1N1 INFLUENZA A VIRUS IN INTRAVENOUS IMMUNOGLOBULIN PREPARATIONS

David K. Hong, D. Lewis, J. Burns, 2011, The Pediatric infectious disease journal.

Single-Cell Analysis of the Neonatal Immune System Across the Gestational Age Continuum

N. Aghaeepour, D. Stevenson, A. Tsai, 2021, Frontiers in Immunology.

Heme oxygenase and the immune system in normal and pathological pregnancies

D. Stevenson, Hui Zhao, R. Wong, 2015, Front. Pharmacol..

Acute Rejection and Cardiac Allograft Vascular Disease Is Reduced by Suppression of Subclinical Cytomegalovirus Infection

B. Narasimhan, H. Valantine, J. Cooke, 2006, Transplantation.

Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors.

Holden T Maecker, H. Maecker, D. Lewis, 2002, The Journal of infectious diseases.

Cellular Immune Responses in Children and Adults Receiving Inactivated or Live Attenuated Influenza Vaccines

D. Lewis, C. Dekker, H. Greenberg, 2006, Journal of Virology.

Title ICOS regulates the generation and function of human CD 4 + Tregin a CTLA-4 dependent manner

Y. Lau, D. Lewis, Zheng Xiang, 2013 .

Generation of human Th1‐like regulatory CD4+ T cells by an intrinsic IFN‐γ‐ and T‐bet‐dependent pathway

Y. Lau, D. Lewis, Zheng Xiang, 2011, European journal of immunology.

From the * Department of Pediatrics , University of Washington and the * Division of Infectious Diseases , Children ' s

D. Lewis, Christopher B Wilson, A. Larsen, 2022 .

Chapter 12 – Neonatal T Cell Immunity and Its Regulation by Innate Immunity and Dendritic Cells

D. Lewis, D. Lewis, 2012 .

Global study of primary immunodeficiency diseases (PI)—diagnosis, treatment, and economic impact: an updated report from the Jeffrey Modell Foundation

J. Orange, L. Notarangelo, D. Lewis, 2011, Immunologic research.

A novel mutation associated with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

D. Lewis, K. Nadeau, R. D. Bhui, 2008, Annals of Allergy, Asthma & Immunology.

T cell development in the fetus and neonate.

D. Lewis, C. Wilson, B. English, 1991, Advances in experimental medicine and biology.

Defective sphingosine-1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

M. Snyder, Linfeng Wu, R. Sobel, 2013, Nature Immunology.

Osteoporosis induced in mice by overproduction of interleukin 4.

S A Goldstein, H. D. Liggitt, E. Effmann, 1993, Proceedings of the National Academy of Sciences of the United States of America.

T cell priming enhances IL-4 gene expression by increasing nuclear factor of activated T cells.

D. Lewis, R. Cron, Y. Wang, 1999, Journal of immunology.

The importance of leukotrienes in airway inflammation in a mouse model of asthma

E. Chi, W. Henderson, D. Lewis, 1996, The Journal of experimental medicine.

Human Neonatal Naive CD4+ T Cells Have Enhanced Activation-Dependent Signaling Regulated by the MicroRNA miR-181a

D. Lewis, V. Ramachandran, Swati Acharya, 2013, The Journal of Immunology.

Protein tyrosine kinase 7: a novel surface marker for human recent thymic emigrants with potential clinical utility

D. Ross, D. Lewis, C. Haines, 2011, Journal of Perinatology.

Gamma‐interferon: an immunoregulatory lymphokine with immunotherapeutic potential

D. Lewis, Christopher B Wilson, 1990, The Pediatric infectious disease journal.

Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function

Li-Sheng Lu, D. Ross, M. Tessier-Lavigne, 2009, The Journal of experimental medicine.

Persistent and Selective Deficiency of CD4+ T Cell Immunity to Cytomegalovirus in Immunocompetent Young Children1

H. Maecker, D. Lewis, W. Tu, 2004, The Journal of Immunology.

AN IMMUNOSUPPRESSIVE AND ANTI-INFLAMMATORY HLA CLASS I-DERIVED PEPTIDE BINDS VASCULAR CELL ADHESION MOLECULE-11

D. Lewis, A. Krensky, C. Clayberger, 2000, Transplantation.

Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses.

Peter O. Krutzik, Erin F. Simonds, G. Nolan, 2010, Cell host & microbe.

Retinoic Acid Hypersensitivity Promotes Peripheral Tolerance in Recent Thymic Emigrants

D. Lewis, C. Weaver, R. Kirkman, 2013, The Journal of Immunology.

Development of CRISPR as a prophylactic strategy to combat novel coronavirus and influenza

Drew Endy, Xueqiu Lin, David B. Lewis, 2020, bioRxiv.

A cell cycle analysis of growth-related genes expressed during T lymphocyte maturation

R. Schimke, D. Lewis, J. Feder, 1990, The Journal of cell biology.

Humoral and Cellular Immune Responses in Children Given Annual Immunization With Trivalent Inactivated Influenza Vaccine

Cornelia L Dekker, Xiao-Song He, Wenwei Tu, 2007, The Pediatric infectious disease journal.

Antiviral CD8 T cells in the control of primary human cytomegalovirus infection in early childhood.

D. Lewis, C. Dekker, H. Greenberg, 2004, The Journal of infectious diseases.

Immunogenicity and tolerability of COVID-19 messenger RNA vaccines in primary immunodeficiency patients with functional B-cell defects

D. Lewis, B. Pinsky, N. Banaei, 2021, Journal of Allergy and Clinical Immunology.

Ontogeny of T Lymphocyte Function in the Neonate

W. M. Weaver, D. Lewis, Christopher B Wilson, 1992, American journal of reproductive immunology.

Avian flu to human influenza.

D. Lewis, D. Lewis, 2006, Annual review of medicine.

Restricted production of interleukin 4 by activated human T cells.

D. Lewis, K. Prickett, C. Wilson, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Transient deficiencies of T-cell-mediated immunity in the neonate.

D. Lewis, D. Randolph, D. Lewis, 2006, Advances in experimental medicine and biology.

Implementing Mass Cytometry at the Bedside to Study the Immunological Basis of Human Diseases: Distinctive Immune Features in Patients with a History of Term or Preterm Birth

Nima Aghaeepour, Ronald J Wong, Gary M Shaw, 2015, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Immunogenicity of a third COVID-19 messenger RNA vaccine dose in primary immunodeficiency disorder patients with functional B-cell defects

D. Lewis, B. Pinsky, L. Hoyte, 2022, The Journal of Allergy and Clinical Immunology: In Practice.

Regulated by the MicroRNA miR-181a Enhanced Activation-Dependent Signaling T Cells Have + Human Neonatal Naive CD4

D. Lewis, V. Ramachandran, Swati Acharya, 2013 .

Mapping the Fetomaternal Peripheral Immune System at Term Pregnancy

G. Nolan, G. Shaw, N. Aghaeepour, 2016, The Journal of Immunology.

Toxicopathology of the Developing Immune System

D. Lewis, G. Parker, D. Weinstock, 2010, Toxicologic pathology.