S. Zorn

发表

Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration

Alexander R. Pico, Mark Ellisman, L. Mucke, 2018, Nature Immunology.

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Caleb Webber, Guy B. Williams, Mara Cercignani, 2019, Brain : a journal of neurology.

Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation.

Anne W. Schmidt, S. Zorn, Y. Lu, 1997, European journal of pharmacology.

Clozapine is a potent and selective muscarinic M4 receptor agonist.

S. Zorn, D. Liston, K. Ward, 1994, European journal of pharmacology.

The discovery of potent and selective dopamine D4 receptor antagonists.

A. Fliri, S. Zorn, W. S. Faraci, 1998, Current opinion in chemical biology.

The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1- azabicyclo[2.2.2]-octan-3-amine as a novel, nonpeptide substance P antagonisst.

J. Lowe, S. Zorn, S. Mclean, 1992, Journal of medicinal chemistry.

Synthesis, SAR and pharmacology of CP-293,019: a potent, selective dopamine D4 receptor antagonist.

D. B. Duignan, A. Fliri, P. Seymour, 1998, Bioorganic & medicinal chemistry letters.

Differential SAR of quinuclidine SP antagonists between rat and human-type receptors

J. Lowe, S. Zorn, R. Snider, 1992, Regulatory Peptides.

Discovery of CP-96,345 and its characterization in disease models involving substance P

J. Lowe, S. Zorn, S. Mclean, 1992, Regulatory Peptides.

P2X7 receptor‐mediated release of microglial prostanoids and miRNAs correlates with reversal of neuropathic hypersensitivity in rats

T. Möller, S. Zorn, A. Hopper, 2022, European journal of pain.

Selective interaction of tricyclic antidepressants with a subclass of rat brain cholinergic muscarinic receptors.

S. Zorn, S. Enna, S. Nomura, 1987, Life sciences.

Cardiovascular effects of cholecystokinin-4 are mediated by the cholecystokinin-B receptor subtype in the conscious guinea pig and dog.

J. Lowe, S. Zorn, A. Fossa, 1997, The Journal of pharmacology and experimental therapeutics.

1-(2-Aminoethyl)-3-methyl-8,9-dihydropyrano[3,2-e]indole: a rotationally restricted phenolic analog of the neurotransmitter serotonin and agonist selective for serotonin (5-HT2-type) receptors.

J. Macor, S. Zorn, B. Koe, 1992, Journal of medicinal chemistry.

3-Benzisothiazolylpiperazine derivatives as potential atypical antipsychotic agents.

Anne W. Schmidt, J. Lowe, P. Seymour, 1996, Journal of medicinal chemistry.

Ziprasidone (CP-88,059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity.

Anne W. Schmidt, J. Lowe, P. Seymour, 1995, The Journal of pharmacology and experimental therapeutics.

5-Phenyl-3-ureidobenzazepin-2-ones as cholecystokinin-B receptor antagonists.

D. Hageman, J. Lowe, S. Zorn, 1994, Journal of medicinal chemistry.

Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment.

S. Zorn, D. Doller, J. Wierońska, 2016, Pharmacology & therapeutics.

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies

M. Papp, S. Zorn, D. Doller, 2014, Psychopharmacology.

Characterization of CP-122,721; a nonpeptide antagonist of the neurokinin NK1 receptor.

Anne W. Schmidt, A. Ganong, P. Seymour, 1996, The Journal of pharmacology and experimental therapeutics.

Inhibition of P2X7 receptors by Lu AF27139 diminishes colonic hypersensitivity and CNS prostanoid levels in a rat model of visceral pain

S. Poda, S. Zorn, S. Hestehave, 2022, Purinergic Signalling.

Discovery of CP-96,345 and its characterization in disease models involving substance P

J. Lowe, S. Zorn, S. Mclean, 1992, Regulatory Peptides.

Characterization in Mammalian Brain of a DARPP‐32 Serine Kinase Identical to Casein Kinase II

P. Greengard, H. Hemmings, J. Girault, 1990, Journal of neurochemistry.

Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor

Nanxin Li, M. Banasr, R. Duman, 2016, Biological Psychiatry.

Inhibition of the potassium channel KCa3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury

T. Möller, S. Poda, S. Zorn, 2017, European journal of pharmacology.

Comparison of the Novel Antipsychotic Ziprasidone with Clozapine and Olanzapine: Inhibition of Dorsal Raphe Cell Firing and the Role of 5-HT1A Receptor Activation

S. Zorn, H. Rollema, J. Sprouse, 1999, Neuropsychopharmacology.

Mechanisms of typical and atypical antipsychotic drug action in relation to dopamine and NMDA receptor hypofunction hypotheses of schizophrenia

J. Lieberman, S. Zorn, G. Duncan, 1999, Molecular Psychiatry.

Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profile.

Anne W. Schmidt, S. Zorn, H. Howard, 2001, European journal of pharmacology.

The pharmacology of weight gain with antipsychotics.

S. Zorn, D. Casey, Stevin H. Zorn, 2001, The Journal of clinical psychiatry.

Selective dopamine D4 receptor antagonists reverse apomorphine-induced blockade of prepulse inhibition

S. Zorn, R. Mansbach, M. Sanner, 1998, Psychopharmacology.

Lu AF21934, a positive allosteric modulator of mGlu4 receptors, reduces the harmaline-induced hyperactivity but not tremor in rats

S. Zorn, D. Doller, Andrzej Pilc, 2014, Neuropharmacology.

Blockade of drug-induced deficits in prepulse inhibition of acoustic startle by ziprasidone

S. Zorn, R. Mansbach, Robert S Mansbach, 2001, Pharmacology Biochemistry and Behavior.

Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139.

J. Hornberg, J. Kilburn, T. Möller, 2021, Journal of medicinal chemistry.

5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex.

Anne W. Schmidt, S. Zorn, Y. Lu, 2000, Biological psychiatry.

5-HT1A receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex

Anne W. Schmidt, S. Zorn, H. Rollema, 2000, Biological Psychiatry.

GABA uptake inhibitors produce a greater antinociceptive response in the mouse tail-immersion assay than other types of GABAergic drugs.

S. Zorn, S. Enna, 1985, Life sciences.

A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index

Karen H. Adams, E. Bullmore, F. Turkheimer, 2021, Biological psychiatry. Cognitive neuroscience and neuroimaging.

The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies

M. Papp, S. Zorn, D. Doller, 2014, Psychopharmacology.

A new class of selective and potent inhibitors of neuronal nitric oxide synthase.

R. Volkmann, J. Lowe, M. Ashton, 1999, Bioorganic & Medicinal Chemistry Letters.

The effect of mouse spinal cord transection on the antinociceptive response to the γ-aminobutyric acid agonists THIP (4, 5, 6, 7-tetrahydroisoxazolo [5, 4-c]pyridine-3-ol) and baclofen

S. Zorn, S. Enna, 1985, Brain Research.

The GABA agonist THIP, attenuates antinociception in the mouse by modifying central cholinergic transmission

S. Zorn, S. Enna, 1987, Neuropharmacology.

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Tobias C. Wood, Karen H. Adams, C. Webber, 2019, Brain : a journal of neurology.

Fibrin-targeting immunotherapy protects against and neurodegeneration.

Alexander R. Pico, Ioanna, Mark Ellisman, 2019 .

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Karen H. Adams, E. Bullmore, F. Turkheimer, 2023, Journal of Neuroinflammation.

Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor

Nanxin Li, M. Banasr, R. Duman, 2016, Biological Psychiatry.

Effects of reserpine on dopamine metabolite in the nucleus accumbens and locomotor activity in freely moving rats

S. Zorn, Y. Sawa, S. Nomura, 1989, Neurochemical Research.