D. Sidransky

A. Chatterjee, D. Sidransky, S. Upadhyay, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Serum protein MALDI profiling to distinguish upper aerodigestive tract cancer patients from control subjects.

R. Irizarry, J. Califano, D. Sidransky, 2003, Journal of the National Cancer Institute.

BRAF mutation in papillary thyroid carcinoma.

P. Ladenson, Zhongmin Guo, B. Trink, 2003, Journal of the National Cancer Institute.

Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer.

C. Moon, Juna Lee, M. Hoque, 2008, Biochemical and biophysical research communications.

Role of the p16 tumor suppressor gene in cancer.

D. Sidransky, W. Liggett, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Increased plasma DNA integrity index in head and neck cancer patients

J. Califano, D. Sidransky, M. Zahurak, 2006, International journal of cancer.

Frequent loss of chromosome 9p21-22 early in head and neck cancer progression.

R. Hruban, D. Sidransky, W. Koch, 1994, Cancer research.

Genetic progression and clonal relationship of recurrent premalignant head and neck lesions.

J. Califano, D. Sidransky, W. Westra, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Prognostic significance of preoperative molecular serum analysis in renal cancer.

B. Trock, F. Marshall, D. Sidransky, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

J. Herman, S. Baylin, E. Gabrielson, 1995, Nature Medicine.

In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development

A. Aliper, Ksenia V Lezhnina, A. Zhavoronkov, 2016, Nature Communications.

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

R. Gibbs, J. Weinstein, D. Muzny, 2011, Science.

NID2 and HOXA9 Promoter Hypermethylation as Biomarkers for Prevention and Early Detection in Oral Cavity Squamous Cell Carcinoma Tissues and Saliva

R. Irizarry, M. Esteller, A. Jaffe, 2011, Cancer Prevention Research.

Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA

Siân Jones, L. Marchionni, E. Fertig, 2015, Nature Communications.

Elevated AKAP12 in paclitaxel-resistant serous ovarian cancer cells is prognostic and predictive of poor survival in patients.

T. Conrads, D. Sidransky, B. Hood, 2015, Journal of proteome research.

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

Meenakshi Malhotra, Alan Bilsland, Amr Amin, 2015, Seminars in cancer biology.

Emerging molecular markers of cancer

David Sidransky, D. Sidransky, 2002, Nature Reviews Cancer.

Detecting colorectal cancer in stool with the use of multiple genetic targets.

S. Goodman, K. Kinzler, B. Vogelstein, 2001, Journal of the National Cancer Institute.

Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma.

D. Sidransky, S. Dong, Sokbom Kang, 2007, Gynecologic oncology.

Advances in cancer detection.

D. Sidransky, D Sidransky, 1996, Scientific American.

Interaction and colocalization of PGP9.5 with JAB1 and p27Kip1

J. Jen, D. Sidransky, E. Ratovitski, 2002, Oncogene.

Proteomic Changes in Oral Keratinocytes Chronically Exposed to Shisha (Water Pipe).

Jayshree Advani, Tejaswini Subbannayya, G. Sathe, 2019, Omics : a journal of integrative biology.

NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis

D. Sidransky, R. Mehra, E. Golemis, 2017, Nature Communications.

Immune profiles in primary squamous cell carcinoma of the head and neck.

Yusuke Nakamura, A. Zhavoronkov, Michael Korzinkin, 2019, Oral oncology.

Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment

Alfonso Valencia, Manuel Hidalgo, Samuel V. Angiuoli, 2014, Clinical Cancer Research.

Activation of the NOTCH pathway in head and neck cancer.

Michael F. Ochs, Ashish Choudhary, Yan Liu, 2014, Cancer research.

Molecular characteristics of non-small cell lung cancer

Michael Ruogu Zhang, K. Buetow, J. Jen, 2001, Proceedings of the National Academy of Sciences of the United States of America.

GSTP1 promoter methylation is associated with recurrence in early stage prostate cancer.

E. Platz, G. Netto, M. Hoque, 2014, The Journal of urology.

Molecular detection of prostate cancer in urine by GSTP1 hypermethylation.

J. Herman, M. Esteller, D. Sidransky, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer.

Rui Henrique, Carmen Jerónimo, David Sidransky, 2002, Urology.

Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma.

J. Epstein, Zhongmin Guo, D. Sidransky, 2003, The Journal of urology.

Endothelin B receptor gene hypermethylation in prostate adenocarcinoma

P. Campos, D. Sidransky, O. Caballero, 2003, Journal of clinical pathology.

Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients.

J. Herman, S. Baylin, M. Esteller, 1999, Cancer research.

DNA of Patients with Lung Cancer Methylation Analysis in Tumor Tissue , Serum , and Plasma Quantitative Adenomatous Polyposis Coli Promoter Updated

D. Sidransky, K. Danenberg, Stephen C. Yang, 2002 .

Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival

David Sidransky, Kumari Wickramasinghe, D. Sidransky, 2001, Oncogene.

Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma.

S. Groshen, P. Laird, D. Beer, 2000, Journal of the National Cancer Institute.

Nucleic acid-based methods for the detection of cancer.

D. Sidransky, D Sidransky, 1997, Science.

Efficacy of weekly docetaxel and bevacizumab in mesenchymal chondrosarcoma: a new theranostic method combining xenografted biopsies with a mathematical model.

Zvia Agur, David Sidransky, M. Wick, 2008, Cancer research.

Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.

David Sidransky, Ning Jin, A. Dackiw, 2007, The Journal of clinical endocrinology and metabolism.

Microsatellite alterations as clonal markers for the detection of human cancer.

Y S Erozan, M. Tockman, F. Askin, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Identification of head and neck squamous cell carcinoma biomarker candidates through proteomic analysis of cancer cell secretome.

Akhilesh Pandey, Aditi Chatterjee, Arivusudar Marimuthu, 2013, Biochimica et biophysica acta.

Genome-Wide and Gene-Specific Epigenomic Platforms for Hepatocellular Carcinoma Biomarker Development Trials

M. Esteller, A. Jaffe, M. Torbenson, 2014, Gastroenterology research and practice.

Death-associated protein kinase promoter hypermethylation in normal human lymphocytes.

J. Califano, D. Sidransky, N. Benoit, 2003, Cancer research.

Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers

J. Herman, M. Esteller, D. Sidransky, 1998, Oncogene.

O6-Methylguanine-DNA Methyltransferase Promoter Hypermethylation Shifts the p53 Mutational Spectrum in Non-Small Cell Lung Cancer

D. Sidransky, S. Ahrendt, Yingchuan Hu, 2001 .

Molecular margin analysis predicts local recurrence after sublobar resection of lung cancer

M. Brock, J. Califano, D. Sidransky, 2005, International journal of cancer.

Detection of bladder cancer recurrence by microsatellite analysis of urine

David Sidransky, D. Sidransky, L. Mao, 1997, Nature Medicine.

Pathway activation strength is a novel independent prognostic biomarker for cetuximab sensitivity in colorectal cancer patients

Alexander M Aliper, Evgeny Izumchenko, David Sidransky, 2015, Human Genome Variation.

Quantitative detection of promoter hypermethylation as a biomarker of acute kidney injury during transplantation.

M. Hoque, D. Sidransky, H. Rabb, 2006, Transplantation proceedings.

Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects.

M. Hoque, D. Sidransky, W. Westra, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Functional analysis of wild-type and malignant glioma derived CDKN2Aβ alleles: Evidence for an RB-independent growth suppressive pathway

W. Cavenee, W. Arap, D. Sidransky, 1997, Oncogene.

MAP2K1 is a potential therapeutic target in erlotinib resistant head and neck squamous cell carcinoma

S. Pinto, Arun H. Patil, Vishalakshi Nanjappa, 2019, Scientific Reports.

Epigenetic inactivation of RASSF1A in head and neck cancer.

M. Lerman, D. Sidransky, N. Benoit, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

High frequency of mitochondrial DNA mutations in breast cancer: potential application for cancer detection

D. Sidransky, M. Sanchez-Cespedes, V. Fazio, 2001 .

Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma

Alexander V. Favorov, Daria A. Gaykalova, Ludmila V. Danilova, 2020, Epigenetics.

Detection of head and neck squamous cell carcinoma among exfoliated oral mucosal cells by microsatellite analysis.

S. Liu, J. Califano, D. Sidransky, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Molecular Detection of Head and Neck Cancer

D. Sidransky, W. Koch, 2003 .

Epigenetic Inactivation of RASSF 1 A in Head and Neck Cancer 1

M. Lerman, D. Sidransky, N. Benoit, 2003 .

Molecular detection of cervical intraepithelial neoplasia and cervical carcinoma by microsatellite analysis of Papanicolaou smears

J. Jen, D. Sidransky, S. Dong, 2001, International journal of cancer.

Molecular markers in cancer diagnosis.

D. Sidransky, 1995, Journal of the National Cancer Institute. Monographs.

Screening of homologous recombination gene polymorphisms in lung cancer patients reveals an association of the NBS1-185Gln variant and p53 gene mutations.

D. Sidransky, S. Ahrendt, M. Sanchez-Cespedes, 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Expression of GULP1 in bronchial epithelium is associated with the progression of emphysema in chronic obstructive pulmonary disease.

P. Illei, M. Hoque, D. Sidransky, 2017, Respiratory medicine.

Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors

J. Jen, D. Sidransky, W. Westra, 1998, Genes, chromosomes & cancer.

Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.

J. Califano, D. Sidransky, W. Westra, 1996, Cancer research.

A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma.

S. Leung, S. Cheung, D. Sidransky, 1994, Cancer research.

Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer

J. Herman, S. Baylin, W. Isaacs, 1997, Genes, chromosomes & cancer.

Tumor and Stem Cell Biology D Np 63 a Confers Tumor Cell Resistance to Cisplatin through the AKT 1 Transcriptional Regulation

A. Chatterjee, M. Hoque, D. Sidransky, 2011 .

DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation.

A. Chatterjee, M. Hoque, D. Sidransky, 2011, Cancer research.

Colorimetric approach to high-throughput mutation analysis.

J. Califano, D. Sidransky, N. Benoit, 2005, BioTechniques.

Associated with p 53 Mutations in Non-Small Cell Lung Cancer Microsatellite Instability at Selected Tetranucleotide Repeats Is Updated

J. Jen, D. Sidransky, Lihua Xu, 2000 .

Brief report: molecular biology and the early detection of carcinoma of the bladder--the case of Hubert H. Humphrey.

R. Hruban, D. Sidransky, P. van der Riet, 1994, The New England journal of medicine.

Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck.

R H Hruban, S. Goodman, R. Hruban, 1995, The New England journal of medicine.

Mutations in Non-Small Cell Lung Cancer p 53 Frequency of Alcohol Consumption and Cigarette Smoking Increase the Updated

J. Jen, D. Sidransky, S. Ahrendt, 2000 .

Mutations in the conserved regions of p53 are infrequent in betel-associated oral cancers from Papua New Guinea.

M. Hollstein, D. Sidransky, R. Montesano, 1994, Cancer research.

Circulating antibodies to p40AIS in the sera of respiratory tract cancer patients

J. Jen, B. Trink, D. Sidransky, 2000, International Journal of Cancer.

Gene expression alterations over large chromosomal regions in cancers include multiple genes unrelated to malignant progression.

Jonathan Pevsner, Nicole Benoit, David Sidransky, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma

J. Jen, B. Trink, D. Sidransky, 2000, International journal of cancer.

A tumor-suppressive role for trypsin in human cancer progression.

K. Mimori, D. Sidransky, M. Mori, 2003, Cancer research.

Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer.

S. Baylin, E. Gabrielson, D. Sidransky, 1994, Cancer research.

p16INK4A adenovirus-mediated gene therapy for human head and neck squamous cell cancer.

D. Sidransky, L. Duan, J. Rocco, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Fine mapping of chromosome 3 in uveal melanoma: identification of a minimal region of deletion on chromosomal arm 3p25.1-p25.2.

David Sidransky, Vito M Fazio, D. Sidransky, 2003, Cancer research.

Oxidized guanine lesions and hOgg1 activity in lung cancer

A. Chatterjee, M. Hoque, D. Sidransky, 2005, Oncogene.

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer.

P. Ladenson, D. Clark, D. Sidransky, 2013, JAMA.

Chromosome 9p21 loss and p16 inactivation in primary sclerosing cholangitis-associated cholangiocarcinoma.

H. Pitt, A. Rashid, D. Sidransky, 1999, The Journal of surgical research.

Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO.

A. Chatterjee, J. Califano, D. Sidransky, 2006, Oral oncology.

Exon 15 BRAF Mutations Are Uncommon in Melanomas Arising in Nonsun-Exposed Sites

D. Sidransky, W. Westra, D. Goldenberg, 2004, Clinical Cancer Research.

DCC promoter hypermethylation in esophageal squamous cell carcinoma

J. Califano, C. Moon, Juna Lee, 2006, International journal of cancer.

The V599E BRAF mutation is uncommon in biliary tract cancers

P. Argani, A. Maitra, I. Wistuba, 2004, Modern Pathology.

Evidence for two bladder cancer suppressor loci on human chromosome 9.

D. Sidransky, K. Tokino, J. Ruppert, 1993, Cancer research.

Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction.

D. Sidransky, Y. Eby, K. Tokino, 1994, Cancer research.

Uses of DNA methylation in cancer diagnosis and risk assessment

D. Sidransky, R. Henrique, C. Jerónimo, 2004 .

An Overview on the Isolation and Analysis of Circulating Tumor DNA in Plasma and Serum

J. Jen, D. Sidransky, Li Wu, 2000, Annals of the New York Academy of Sciences.

Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study.

M. Brock, J. Jen, D. Sidransky, 2002, The Journal of thoracic and cardiovascular surgery.

Absence of V599E BRAF mutations in desmoplastic melanomas

J. Davison, M. Hoque, D. Sidransky, 2005, Cancer.

Advances in Brief p 53 Mutation and MDM 2 Amplification in Human Soft Tissue Sarcomas 1

P. Meltzer, D. Hill, K. Kinzler, 2006 .

Epithelial precursor lesions

N. Gale, J. Califano, D. Sidransky, 2005 .

Phospho-ΔNp63α/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure

B. Trink, D. Sidransky, S. Sinha, 2010 .

Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma.

A. Hildesheim, D. Sidransky, M. Greenberg, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Detection and Quantitation of Human Papillomavirus DNA in the Plasma of Patients with Cervical Carcinoma 1

A. Hildesheim, D. Sidransky, M. Greenberg, 2002 .

p53 associates with and targets Delta Np63 into a protein degradation pathway.

B. Trink, D. Sidransky, E. Ratovitski, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Betel-associated Oral Cancers from Papua New Guinea Are Infrequent in p 53 Mutations in the Conserved Regions of Updated

M. Hollstein, D. Sidransky, R. Montesano, 2016 .

BRAF T1796A transversion mutation in various thyroid neoplasms.

P. Ladenson, D. Sidransky, V. Vasko, 2004, The Journal of clinical endocrinology and metabolism.

Detection of Merkel cell virus and correlation with histologic presence of Merkel cell carcinoma in sentinel lymph nodes

J. Taube, J. Califano, D. Sidransky, 2012, British Journal of Cancer.

Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission

J. Califano, D. Sidransky, W. Westra, 2010, International journal of cancer.

Multiomic analysis of oral keratinocytes chronically exposed to shisha

Jayshree Advani, Tejaswini Subbannayya, P. Rajagopalan, 2019, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

AssociationBetween BRAF V 600 EMutationand MortalityinPatientsWithPapillaryThyroidCancer

Neill, P. Ladenson, D. Clark, 2013 .

AssociationBetween BRAFV600EMutationand MortalityinPatientsWithPapillaryThyroidCancer

P. Ladenson, D. Clark, D. Sidransky, 2013 .

RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI‐associated endometrial carcinoma

D. Sidransky, S. Dong, Sokbom Kang, 2006, International journal of cancer.

T1799A BRAF mutations in conjunctival melanocytic lesions.

I. Chowers, D. Weinberger, D. Sidransky, 2005, Investigative ophthalmology & visual science.

Mutational Analysis of BRAF in Fine Needle Aspiration Biopsies of the Thyroid: A Potential Application for the Preoperative Assessment of Thyroid Nodules

D. Clark, D. Sidransky, W. Westra, 2004, Clinical Cancer Research.

BRAF mutations in anaplastic thyroid carcinoma: implications for tumor origin, diagnosis and treatment

D. Sidransky, W. Westra, R. Henrique, 2004, Modern Pathology.

Lack of BRAF mutation in primary uveal melanoma.

I. Chowers, D. Sidransky, J. Pe’er, 2003, Investigative ophthalmology & visual science.

Phenotypic and genotypic disparity in premalignant lesions: of calm water and crocodiles.

D. Sidransky, W. Westra, 1998, Journal of the National Cancer Institute.

Mutational spectra and immunohistochemical analyses of p53 in human cancers.

B. Vogelstein, C. Harris, M. Hollstein, 1992, Chest.

A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma.

J. Nieva, C. Chung, M. Schell, 2015, Oral oncology.

Lactoferrin Down-Regulates G1 Cyclin-Dependent Kinases during Growth Arrest of Head and Neck Cancer Cells

D. Sidransky, C. Monitto, Khalid M. Minhas, 2004, Clinical Cancer Research.

HIST1H2BB and MAGI2 Methylation and Somatic Mutations as Precision Medicine Biomarkers for Diagnosis and Prognosis of High-grade Serous Ovarian Cancer

J. Herman, J. Eshleman, I. Shih, 2020, Cancer Prevention Research.

Dysregulation of splicing proteins in head and neck squamous cell carcinoma

Nandini A. Sahasrabuddhe, A. Pandey, R. S. Nirujogi, 2016, Cancer biology & therapy.

Differential DNA Hypermethylation of Critical Genes Mediates the Stage-Specific Tobacco Smoke-Induced Neoplastic Progression of Lung Cancer

J. Califano, D. Sidransky, S. Thiagalingam, 2005, Clinical Cancer Research.

Genome-wide promoter analysis uncovers portions of the cancer methylome.

E. Schuuring, A. V. D. Van Der Zee, J. Califano, 2008, Cancer research.

Somatic mitochondrial mutation discovery using ultra-deep sequencing of the mitochondrial genome reveals spatial tumor heterogeneity in head and neck squamous cell carcinoma.

Daria A. Gaykalova, A. Pearson, A. Chatterjee, 2019, Cancer letters.

TIMP3 Promoter Methylation is an Independent Prognostic Factor for Bladder Cancer

S. Goodman, B. Trock, M. Hoque, 2009 .

Detection of LOH and Mitochondrial DNA Alterations in Ductal Lavage and Nipple Aspirate Fluids from High-risk Patients

Minetta C. Liu, Baljit Singh, C. Isaacs, 2004, Breast Cancer Research and Treatment.

Functional characterization of alternatively spliced GSN in head and neck squamous cell carcinoma

Alexander V. Favorov, Daria A. Gaykalova, C. Chung, 2018, Translational research : the journal of laboratory and clinical medicine.

Inverse Correlation between Cyclin A1 Hypermethylation and p53 Mutation in Head and Neck Cancer Identified by Reversal of Epigenetic Silencing

S. Nomoto, J. Califano, M. Hoque, 2004, Cancer Research.

Cigarette smoke induces mitochondrial metabolic reprogramming in lung cells.

Jayshree Advani, A. Chatterjee, T. Prasad, 2018, Mitochondrion.

Promoter methylation of MCAM, ERα and ERβ in serum of early stage prostate cancer patients

A. Partin, E. Humphreys, M. Hoque, 2017, Oncotarget.

Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers.

J. Herman, M. Esteller, D. Sidransky, 2001, Cancer research.

Advances in Brief O 6-Methylguanine-DNA Methyltransferase Promoter Hypermethylation Shifts the p 53 Mutational Spectrum in Non-Small Cell Lung Cancer 1

D. Sidransky, S. Ahrendt, Yingchuan Hu, 2001 .

Quantitative GSTP1 methylation and the detection of prostate adenocarcinoma in sextant biopsies.

S. Goodman, A. Partin, P. Walsh, 2003, Journal of the National Cancer Institute.

Predominance of brain tumors in an extended Li‐Fraumeni (SBLA) kindred, including a case of Sturge‐Weber syndrome

Z. Wszolek, D. Sidransky, H. Lynch, 2000, Cancer.

PD-L 1 Expression in the Merkel Cell Carcinoma Microenvironment : Association with In fl ammation , Merkel Cell Polyomavirus , and Overall Survival

J. Taube, E. Lipson, D. Sidransky, 2013 .

Evidence for a causal association between human papillomavirus and a subset of head and neck cancers.

D. Sidransky, M. Zahurak, W. Westra, 2000, Journal of the National Cancer Institute.

Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity

J. Califano, D. Sidransky, W. Westra, 2004, Head & neck.

Real-Time Quantitative PCR Demonstrates Low Prevalence of Human Papillomavirus Type 16 in Premalignant and Malignant Lesions of the Oral Cavity 1

J. Califano, D. Sidransky, W. Westra, 2002 .

Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity.

J. Califano, D. Sidransky, W. Westra, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma.

D. Sidransky, W. Westra, W. Koch, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor

Daria A. Gaykalova, Nandini A. Sahasrabuddhe, A. Zhavoronkov, 2018, Oncoscience.

PGP9.5 as a candidate tumor marker for non-small-cell lung cancer.

S. Goodman, J. Jen, D. Sidransky, 1999, The American journal of pathology.

Selective radiosensitization of p53–deficient cells by caffeine–mediated activation of p34cdc2 kinase

D. Sidransky, Richard J. Jones, M. Collector, 1996, Nature Medicine.

Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors.

G. Riggins, M. Goggins, S. Kern, 1998, Cancer research.

Cancer screening based on genetic alterations in human tumors.

D. Sidransky, L. Mao, 1994, Cancer research.

SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling

N. Mukhopadhyay, A. Gazdar, P. Fisher, 2012, Journal of Molecular Medicine.

A Pilot Clinical Study of Treatment Guided by Personalized Tumorgrafts in Patients with Advanced Cancer

M. Hidalgo, D. Sidransky, M. Wick, 2011, Molecular Cancer Therapeutics.

Regulation of p53 Family Member Isoform Δ Np63 α by the Nuclear Factor- κ B Targeting Kinase I κ B Kinase β

A. Chatterjee, D. Sidransky, R. Ravi, 2010 .

O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer.

D. Sidransky, S. Ahrendt, P. Wolf, 2001, Cancer research.

Real-Time Gap Ligase Chain Reaction

David C. Thomas, J. Califano, D. Sidransky, 2004, Clinical Cancer Research.

Sensitization to UV-induced apoptosis by the histone deacetylase inhibitor trichostatin A (TSA).

D. Sidransky, F. Carrier, M. Kim, 2005, Experimental cell research.

Partial allelotype of carcinoma in situ of the human bladder.

J. Epstein, D. Sidransky, P. Cairns, 1995, Cancer research.

Multiple Mechanisms of p 16 @ NK 4 AInactivation in Non-Small Cell Lung Cancer Cell Lines

C. D. Edwards, M. Ewen, B. Rollins, 2022 .

Short Communication PGP9.5 As a Candidate Tumor Marker for Non-Small-Cell Lung Cancer

S. Goodman, J. Jen, D. Sidransky, 1999 .

Advances in Brief Inactivation of the DNA Repair Gene O 6-Methylguanine-DNA Methyltransferase by Promoter Hypermethylation Is Associated with G to A Mutations in Kras in Colorectal Tumorigenesis 1

J. Herman, S. Baylin, M. Esteller, 2000 .

Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies

Sassan Noazin, D. Sidransky, R. Guerrero-Preston, 2017, Oncotarget.

Molecular Triage of Premalignant Lesions in Liquid-Based Cervical Cytology and Circulating Cell-Free DNA from Urine, Using a Panel of Methylated Human Papilloma Virus and Host Genes

B. Trock, L. Florea, D. Sidransky, 2016, Cancer Prevention Research.

Habitual Risk Factors for Head and Neck Cancer

C. Moon, Juna Lee, B. Trink, 2004, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung.

David Sidransky, Manel Esteller, S. Nomoto, 2002, Cancer research.

Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma.

R. Hruban, D. Sidransky, W. Benedict, 1994, Cancer research.

Pathology & Genetics Head and Neck Tumours

D. Sidransky, J. Eveson, P. Reichart, 2007 .

Second esophageal tumors in patients with head and neck squamous cell carcinoma: an assessment of clonal relationships.

J. Califano, D. Sidransky, W. Westra, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Ribonucleases as a Novel Pro-Apoptotic Anticancer Strategy: Review of the Preclinical and Clinical Data for Ranpirnase

D. Sidransky, A. Navon, J. Costanzi, 2005, Cancer investigation.

An allelotype of papillary thyroid cancer

J. Califano, D. Sidransky, W. Westra, 1996, International journal of cancer.

Chronic Cigarette Smoke Mediated Global Changes in Lung Mucoepidermoid Cells: A Phosphoproteomic Analysis.

Nandini A. Sahasrabuddhe, S. Pinto, Jayshree Advani, 2017, Omics : a journal of integrative biology.

Frequent Loss of Chromosome Arms 8p and 13q in Collecting Duct Carcinoma (CDC) of the Kidney

J. Brooks, F. Marshall, W. Isaacs, 1995, Genes, chromosomes & cancer.

Assessment of gene promoter hypermethylation for detection of cervical neoplasia

H. Boezen, H. Hollema, E. Schuuring, 2006, International journal of cancer.

Detailed deletion mapping at chromosome 9p21 in non‐small cell lung cancer by microsatellite analysis and fluorescence in situ hybridization

J. Jen, D. Sidransky, W. Westra, 1997, International journal of cancer.

Forced cytochrome B gene mutation expression induces mitochondrial proliferation and prevents apoptosis in human uroepithelial SV‐HUC‐1 cells

M. Hoque, D. Sidransky, S. Upadhyay, 2009, International journal of cancer.

Cellular FLICE-like Inhibitory Protein Long Form (c-FLIPL) Overexpression is Related to Cervical Cancer Progression

D. Sidransky, R. Guerrero-Preston, J. Roa, 2013, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Quantitative GSTP1 methylation levels correlate with Gleason grade and tumor volume in prostate needle biopsies.

J. Epstein, Ming Zhou, D. Sidransky, 2004, The Journal of urology.

U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha.

A. Chatterjee, B. Trink, D. Sidransky, 2008, Cell cycle.

Epstein‐Barr Virus in Head and Neck Cancer Assessed by Quantitative Polymerase Chain Reaction

J. Califano, D. Sidransky, W. Westra, 2004, The Laryngoscope.

Local Controlled Delivery of Anti-Neoplastic RNAse to the Brain

D. Sidransky, A. Domb, H. Brem, 2009, Pharmaceutical Research.

Infrequent p53 gene mutations in medulloblastomas.

B. Vogelstein, D. Bigner, S. Bigner, 1991, Cancer research.

In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia

Daria A. Gaykalova, Ksenia V Lezhnina, A. Zhavoronkov, 2017, Cell Death Discovery.

Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress

A. Chatterjee, T. DeWeese, D. Sidransky, 2006, BMC Cancer.

IncreasedMitochondrial DNAContent in Saliva Associatedwith Head and Neck Cancer

A. Carvalho, D. Sidransky, M. Zahurak, 2005 .

Growth of Malignant Non-CNS Tumors Alters Brain Metabolome

B. Kolb, D. Wishart, O. Kovalchuk, 2018, Front. Genet..

Mitochondrial DNA mutations in human cancer

A. Chatterjee, D. Sidransky, E. Mambo, 2006, Oncogene.

Detection of mitochondrial deoxyribonucleic acid alterations in urine from urothelial cell carcinoma patients

L. Kiemeney, P. Fisher, R. Mathies, 2012, International journal of cancer.

Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma.

D. Sidransky, W. Nelson, C. Lopes, 2001, Journal of the National Cancer Institute.

PGP 9 . 5 Methylation in Diffuse-Type Gastric Cancer

D. Sidransky, M. Mori, M. Osada, 2006 .

Predicting Cancer Following a Diagnosis of High-Grade Prostatic Intraepithelial Neoplasia on Needle Biopsy: Data on Men With More Than One Follow-Up Biopsy

D. Sidransky, 2001 .

Inactivation of LKB 1 / STK 11 Is a Common Event in Adenocarcinomas of the Lung 1

S. Nomoto, J. Herman, M. Esteller, 2002 .

Multiple head and neck tumors: evidence for a common clonal origin.

E. Gabrielson, D. Sidransky, W. Westra, 1996, Cancer research.

FluorescenceVisualization in Oral Neoplasia : Shedding Light on an Old Problem 55 Commentary on Poh et al . , p . 6716

D. Sidransky, W. Westra, 2006 .

Comparative microsatellite analysis in discerning origin of disseminated tumor: the case of a patient with malignant ascites and a history of multiple tumors.

D. Sidransky, W. Westra, C. Eisenberger, 1999, Human pathology.

Circulating DNA: What We Know and What We Need to Learn

D. Sidransky, 2000 .

NMDA receptor type 2A at 16p13 is epigenetically inactivated in human colorectal carcinoma

C. Moon, D. Sidransky, Janghee Woo, 2006 .

Assembly and Initial Characterization of a Panel of 85 Genomically Validated Cell Lines from Diverse Head and Neck Tumor Sites

Mei Zhao, David Sidransky, Gary L Clayman, 2011, Clinical Cancer Research.

Tyrosine Phosphorylation Profiling Revealed the Signaling Network Characteristics of CAMKK2 in Gastric Adenocarcinoma

A. Chatterjee, H. Gowda, D. Sidransky, 2022, Frontiers in Genetics.

Genetic and Epigenetic screening for gene alterations of the chromatin‐remodeling factor, SMARCA4/BRG1, in lung tumors

David Sidransky, Manel Esteller, Julian Carretero, 2004, Genes, chromosomes & cancer.

Understanding the MIG6-EGFR Signaling Axis in Lung Tumorigenesis.

D. Sidransky, E. Izumchenko, 2015, Cancer discovery.

MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel

G. Gallia, A. Olivi, P. Burger, 2015, Journal of Clinical Neuroscience.

Absence of intragenic mismatch mutations in small cell lung cancers with microsatellite instability

E. Gabrielson, D. Sidransky, R. Anbazhagan, 1999, International journal of cancer.

Antiviral effect of ranpirnase against Ebola virus.

T. Hodge, D. Sidransky, Alexander N. Freiberg, 2016, Antiviral research.

Regulation of ΔNp63α by NFκΒ

A. Chatterjee, D. Sidransky, Xiaofei Chang, 2010, Cell cycle.

Novel suppressor loci on chromosome 14q in primary bladder cancer.

T. Polascik, D. Sidransky, P. Cairns, 1995, Cancer research.

p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer.

H. Pitt, A. Rashid, D. Sidransky, 2000, Journal of hepato-biliary-pancreatic surgery.

ΔNp63α Up-Regulates the Hsp70 Gene in Human Cancer

Guojun Wu, Zhongmin Guo, J. Califano, 2005, Cancer Research.

Np 63 A UpRegulates the Hsp 70 Gene in Human Cancer

Guojun Wu, Zhongmin Guo, J. Califano, 2005 .

Frequent 14-3-3σ promoter methylation in benign and malignant prostate lesions

A. Carvalho, M. Hoque, D. Sidransky, 2005 .

Loss of chromosome arms 3p and 9p and inactivation of P16 INK4a in normal epithelium of patients with primary lung cancer

J. Herman, M. Esteller, J. Jen, 2001, Genes, chromosomes & cancer.

Multi-Omics Analysis to Characterize Cigarette Smoke Induced Molecular Alterations in Esophageal Cells

Vishalakshi Nanjappa, A. Chatterjee, H. Gowda, 2020, Frontiers in Oncology.

Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes

Jayshree Advani, Arun H. Patil, Vishalakshi Nanjappa, 2018, Scientific Reports.

A Novel pl 6 INK 4 ATranscript 1

C. D. Edwards, B. Rollins, G. Shapiro, 2006 .

Advances in Brief Inherited p 53 Gene Mutations in Breast Cancer 1

B. Vogelstein, T. Tokino, B. Zehnbauer, 2006 .

p16 and p16 beta are potent growth suppressors of head and neck squamous carcinoma cells in vitro.

D. Sidransky, S. Ahrendt, W. Koch, 1996, Cancer research.

Molecular analysis of effectiveness of Mohs' surgical technique

D. Sidransky, Stanley J. Miller, W. Westra, 1996, The Lancet.

Allelotype of salivary gland tumors.

J. Califano, D. Sidransky, W. Westra, 1996, Cancer research.

A Novel pl6INK4ATranscript1

C. D. Edwards, B. Rollins, G. Shapiro, 1995 .

p53 gene mutations as markers of tumor spread in synchronous oral cancers.

R. Hruban, D. Sidransky, W. Koch, 1994, Archives of otolaryngology--head & neck surgery.

Positive Correlation of Tissue Inhibitor of Metalloproteinase‐3 and Death‐Associated Protein Kinase Hypermethylation in Head and Neck Squamous Cell Carcinoma

Steven S. Chang, A. Carvalho, J. Califano, 2007, The Laryngoscope.

Activationof the NOTCH Pathway inHeadandNeckCancer

Daria A. Gaykalova, A. Adai, Yan Liu, 2014 .

Molecular and Cellular Pathobiology Activationof the NOTCH Pathway inHeadandNeckCancer

Daria A. Gaykalova, A. Adai, C. Chung, 2014 .

Mutator phenotype in a subset of chronic lymphocytic leukemia.

D. Sidransky, P. Wang, R. Gartenhaus, 1996, Blood.

D Np63 a Confers Tumor Cell Resistance to Cisplatin through the AKT1 Transcriptional Regulation

A. Chatterjee, M. Hoque, D. Sidransky, 2011 .

Germline translocation t(5;20)(p15;q11) and familial transitional cell carcinoma.

P. Walsh, D. Sidransky, C. Griffin, 1996, The Journal of urology.

Mitochondrial DNA Mutation in Normal Margins and Tumors of Recurrent Head and Neck Squamous Cell Carcinoma Patients

J. Califano, D. Sidransky, W. Westra, 2010, Cancer Prevention Research.

Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma.

T. Polascik, D. Sidransky, P. Cairns, 1995, Cancer research.

Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome.

J. Califano, C. Moon, S. Jang, 2010, Genomics.

Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma

A. Zhavoronkov, Charles R. Cantor, A. Csoka, 2016, Cell cycle.

A putative oncogenic role for MPP11 in head and neck squamous cell cancer.

P. Hieter, J. Jen, D. Sidransky, 2000, Cancer research.

Distinct pattern of p53 phosphorylation in human tumors

C. Harris, D. Sidransky, Z. Ronai, 2001, Oncogene.

Molecular genetics and biochemical mechanisms in bladder cancer. Oncogenes, tumor suppressor genes, and growth factors.

E. Messing, D. Sidransky, 1992, The Urologic clinics of North America.

Degenerate oligonucleotide-primed PCR (DOP-PCR): evaluation of its reliability for screening of genetic alterations in neoplasia.

J. Jen, D. Sidransky, M. Sanchez-Cespedes, 1998, BioTechniques.

DeltaNp63 induces beta-catenin nuclear accumulation and signaling.

S. Nomoto, J. Califano, B. Trink, 2002, Cancer cell.

Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice—an Aging Connection

B. Kolb, O. Kovalchuk, Y. Ilnytskyy, 2018, Front. Genet..

Epigenetic silencing of S100A2 in bladder and head and neck cancers

J. Califano, C. Moon, Juna Lee, 2015, Oncoscience.

Is human patched the gatekeeper of common skin cancers?

D. Sidransky, 1996, Nature Genetics.

Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl‐2 expression and increased susceptibility to cisplatin‐induced apoptosis

J. Grandis, D. Sidransky, S. Xi, 2004, Head & neck.

SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling

N. Mukhopadhyay, A. Gazdar, P. Fisher, 2013, Journal of Molecular Medicine.

Prioritizing phase I treatment options through preclinical testing on personalized tumorgraft.

M. Hidalgo, D. Sidransky, M. Wick, 2012, Journal of Clinical Oncology.

Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes

M. Hoque, B. Trink, D. Sidransky, 2008, Cell cycle.

Galectin-1 promotes the invasion of bladder cancer urothelia through their matrix milieu

D. Sidransky, D. Pally, A. Chatterjee, 2018, bioRxiv.

Absence of ST7 gene alterations in human cancer.

D. Sidransky, S. Dong, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

p63 and p73: teammates or adversaries?

B. Trink, D. Sidransky, E. Ratovitski, 2006, Cancer cell.

PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40 kDa (PRAS40)

A. Zhavoronkov, A. Pandey, S. Navani, 2019, Journal of Cell Communication and Signaling.

Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.

J. Herman, M. Esteller, W. Isaacs, 1997, Cancer research.

Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients

D. Sidransky, S. Halachmi, M. Schoenberg, 1997, International journal of cancer.

CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer

L. Kiemeney, P. Meltzer, J. Trent, 2004, Nature Medicine.

Cellular transformation by cigarette smoke extract involves alteration of glycolysis and mitochondrial function in esophageal epithelial cells

Juna Lee, D. Sidransky, Yiping Huang, 2010, International journal of cancer.

Neurofilament Heavy Polypeptide Regulates the Akt-β-Catenin Pathway in Human Esophageal Squamous Cell Carcinoma

Juna Lee, B. Trink, D. Sidransky, 2010, PloS one.

Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck.

R H Hruban, S. Goodman, R. Hruban, 1995, The New England journal of medicine.

Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma

Guojun Wu, B. Trink, D. Sidransky, 2008, Oncogene.

Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer.

J. Califano, B. Trink, D. Sidransky, 2008, Biochemical and biophysical research communications.

Detection of BRAF mutation on fine needle aspiration biopsy specimens: a new diagnostic tool for papillary thyroid cancer.

P. Ladenson, D. Sidransky, M. Xing, 2004, The Journal of clinical endocrinology and metabolism.

Poster 7: A Genetic Progression Model for Head and Neck Cancer: Implications for Field Cancerization

S. Piantadosi, J. Califano, D. Sidransky, 1996, Cancer research.

Clonal expansion of p53 mutant cells is associated with brain tumour progression

T. Mikkelsen, B. Vogelstein, D. Sidransky, 1992, Nature.

BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agents.

W. El-Deiry, D. Sidransky, Richard J. Jones, 1995, Blood.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Gloria S. Huang, Rob J. Kulathinal, C. Smythe, 2015, Seminars in cancer biology.

Abstract 1287: Epigenetic deregulation of breast cancer is associated with DNA Repair Capacity.

D. Sidransky, R. Guerrero-Preston, K. Ostrow, 2013 .

Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors

M. Hidalgo, H. Pass, R. Maki, 2017, Annals of oncology : official journal of the European Society for Medical Oncology.

Molecular Detection of Primary Bladder Cancer by Microsatellite Analysis

Y S Erozan, D. Sidransky, A. Merlo, 1996, Science.

Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer

Nandini A. Sahasrabuddhe, A. Pandey, S. Navani, 2015, BMC Cancer.

Induction of markers of normal differentiation in human colon carcinoma cells by the v-rasH oncogene.

M. Carroll, R. Lupu, D. Sidransky, 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Genetic Alterations in Urinary Bladder Carcinosarcoma: Evidence of a Common Clonal Origin

O. Nativ, J. Epstein, D. Sidransky, 2000, European Urology.

Alterations of GPI transamidase subunits in head and neck squamous carcinoma

Zhongmin Guo, J. Califano, B. Trink, 2007, Molecular Cancer.

Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer.

Xin Huang, Aditi Chatterjee, David Sidransky, 2006, Cancer research.

Role of human aquaporin 5 in colorectal carcinogenesis.

C. Moon, J. Soria, S. Jang, 2008, The American journal of pathology.

Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation.

J. Califano, C. Moon, J. Soria, 2008, Cancer letters.

Expression of Aquaporin 5 (AQP5) Promotes Tumor Invasion in Human Non Small Cell Lung Cancer

C. Moon, J. Soria, S. Jang, 2008, PloS one.

The effect of aquaporin 5 overexpression on the Ras signaling pathway.

David Sidransky, Se Jin Jang, C. Moon, 2008, Biochemical and biophysical research communications.

Membrane trafficking of AQP5 and cAMP dependent phosphorylation in bronchial epithelium.

J. Califano, C. Moon, J. Soria, 2008, Biochemical and biophysical research communications.

Suprabasin Is Hypomethylated and Associated with Metastasis in Salivary Adenoid Cystic Carcinoma

Daria A. Gaykalova, J. Califano, D. Sidransky, 2012, PloS one.

Integrated, Genome-Wide Screening for Hypomethylated Oncogenes in Salivary Gland Adenoid Cystic Carcinoma

C. Moskaluk, J. Califano, M. Hoque, 2011, Clinical Cancer Research.

Evaluation of MYB promoter methylation in salivary adenoid cystic carcinoma.

J. Califano, D. Sidransky, P. Ha, 2011, Oral oncology.

Human Cancer Biology Integrated , Genome-Wide Screening for Hypomethylated Oncogenes in Salivary Gland Adenoid Cystic Carcinoma

C. Moskaluk, J. Califano, M. Hoque, 2011 .

Quantitative Methylation Profiles for Multiple Tumor Suppressor Gene Promoters in Salivary Gland Tumors

J. Califano, M. Hoque, D. Sidransky, 2010, PloS one.

Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix.

H. S. Kim, D. Sidransky, S. Dong, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

Kathleen R. Cho, M. Tockman, W. Isaacs, 1995, Nature Genetics.

Hypermethylation of the Pendred syndrome gene SLC26A4 is an early event in thyroid tumorigenesis.

P. Ladenson, Guojun Wu, D. Sidransky, 2003, Cancer research.

Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma.

Katsuya Yamashita, Akimasa Nakao, David Sidransky, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors.

S. Nomoto, M. Esteller, D. Sidransky, 2001, Cancer research.

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids.

J. Jen, D. Sidransky, M. Buta, 2000, Science.

Head and Neck Cancer in Nonsmokers:

D. Sidransky, M. Zahurak, W. Koch, 2009 .

Head and Neck Cancer in CNonsmokers: A Distinct Clinical and Molecular Entity

D. Sidransky, M. Zahurak, W. Koch, 1999, The Laryngoscope.

Aquaporin expression in human lymphocytes and dendritic cells

C. Moon, J. Soria, Juna Lee, 2004, American journal of hematology.

Correction: Expression of Aquaporin 5 (AQP5) Promotes Tumor Invasion in Human Non Small Cell Lung Cancer

C. Moon, J. Soria, S. Jang, 2008, PLoS ONE.

p16(MTS-1/CDKN2/INK4a) in cancer progression.

D. Sidransky, J. Rocco, D Sidransky, 2001, Experimental cell research.

Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer.

J. Jen, D. Sidransky, S. Ahrendt, 2000, Cancer research.

Detection of serum deoxyribonucleic acid methylation markers: a novel diagnostic tool for thyroid cancer.

P. Ladenson, A. Carvalho, D. Sidransky, 2006, The Journal of clinical endocrinology and metabolism.

Adenoid cystic carcinoma: emerging role of translocations and gene fusions

D. Sidransky, E. Izumchenko, P. Ha, 2016, Oncotarget.

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.

S Srivastava, S N Thibodeau, R Fodde, 1998, Cancer research.

Role of the NOTCH Signaling Pathway in Head and Neck Cancer

Daria A. Gaykalova, A. Zhavoronkov, E. Fertig, 2018 .

Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features

R. Karchin, C. Chung, J. Califano, 2015, Cancer Prevention Research.

Molecular detection approaches for smoking associated tumors

D. Sidransky, S. Ahrendt, Yingchuan Hu, 2002, Oncogene.

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer.

L. Marchionni, G. Netto, L. Schultz, 2011, Cancer research.

Serial Analysis of Gene Expression in Non-Small Cell Lung Cancer1

J. Jen, D. Sidransky, S. Madden, 1998 .

Multiple strand displacement amplification of mitochondrial DNA from clinical samples

W. Rom, D. Sidransky, C. O’Connell, 2008, BMC Medical Genetics.

Quantitative assessment of promoter methylation profiles in thyroid neoplasms.

P. Ladenson, M. Hoque, D. Sidransky, 2005, The Journal of clinical endocrinology and metabolism.

Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer

A. Carvalho, M. Hoque, D. Sidransky, 2006, Journal of Molecular Medicine.

Somatic mutation and gain of copy number of PIK3CA in human breast cancer

Xin Huang, David Goldenberg, Aditi Chatterjee, 2005, Breast Cancer Research.

Human Cancers Associated with Aberrant DNA Methylation in All Common Gene Is Frequently CDKN 2 / p 16 / MTS 1 Inactivation of the Updated

J. Herman, S. Baylin, J. Issa, 2006 .

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

J. Herman, S. Baylin, J. Issa, 1995, Cancer research.

Characterization of the Methylation Patterns in Human Papillomavirus Type 16 Viral DNA in Head and Neck Cancers

J. Saunders, D. Sidransky, W. Westra, 2011, Cancer Prevention Research.

PARD3 Inactivation in Lung Squamous Cell Carcinomas Impairs STAT3 and Promotes Malignant Invasion.

Elisabeth Brambilla, David Sidransky, Julian Carretero, 2015, Cancer research.

Inactivation in Lung Squamous Cell Carcinomas Impairs STAT 3 and Promotes Malignant Invasion

E. Brambilla, S. Lantuejoul, S. Verdura, 2015 .

Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokers.

S. Piantadosi, J. Jen, D. Sidransky, 2001, Cancer research.

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy

A. Zhavoronkov, L. Marchionni, D. Sidransky, 2018, Nature Communications.

Altered Sumoylation of p63α Contributes to the Split-Hand/Foot Malformation Phenotype

Guojun Wu, Zhongmin Guo, B. Trink, 2004, Cell cycle.

Identification of hypermethylated genes associated with cisplatin resistance in human cancers.

David Sidransky, Joseph A Califano, Steven S. Chang, 2010, Cancer research.

Cancer epigenetics: above and beyond

Mariana Brait, David Sidransky, D. Sidransky, 2011, Toxicology mechanisms and methods.

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

R. Irizarry, L. van Neste, D. Sidransky, 2014, Epigenetics.

Intraoperative molecular margin analysis in head and neck cancer.

J. Califano, D. Sidransky, W. Westra, 2004, Archives of otolaryngology--head & neck surgery.

Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer.

D. Sidransky, K. Danenberg, Stephen C. Yang, 2002, Cancer research.

Identification of guanine nucleotide-binding protein γ-7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling

J. Califano, D. Sidransky, W. Westra, 2013, International journal of oncology.

Bifurcated Tumor Progression Pathway Allelotype of Posterior Uveal Melanoma : Implications for a

D. Sidransky, S. Merbs, P. Parrella, 2013 .

Promoter DNA Methylation of Oncostatin M receptor-β as a Novel Diagnostic and Therapeutic Marker in Colon Cancer

G. Meijer, D. Sidransky, B. Carvalho, 2009, PloS one.

Head and Neck Cancer Mutations Increases with Progression of p 53 The Incidence of Updated Version

D. Sidransky, Y. Eby, J. Ruppert, 2007 .

Advances in Brief The Incidence of p 53 Mutations Increases with Progression of Head and Neck Cancer

R. Hruban, D. Sidransky, Y. Eby, 2007 .

Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma.

A. Carvalho, J. Califano, C. Moon, 2006, Cancer research.

Participation of p 53 Protein in the Cellular Response to DNA Damage 1

B. Vogelstein, D. Sidransky, M. Kastan, 2006 .

Advances in Brief High Frequency of piÃ 3 ( CDKN 2 / MTS-1 / INK 4 A ) Inactivation in Head and Neck Squamous Cell Carcinoma 1 ' 2

Wayne, J. Bartek, D. Sidransky, 2006 .

Microsatellite analysis of serum DNA in patients with head and neck cancer

D. Sidransky, C. Eisenberger, Li Wu, 2004, International journal of cancer.

Molecular staging of head and neck squamous carcinoma

Joseph A. Brennan, David Sidransky, D. Sidransky, 1996, Cancer and Metastasis Reviews.

Genome-wide genetic characterization of bladder cancer: a comparison of high-density single-nucleotide polymorphism arrays and PCR-based microsatellite analysis.

Paul Cairns, David Sidransky, M. Hoque, 2003, Cancer research.

Mutations and Survival in Stage I Non-Small-Cell Lung Cancer : Results of a Prospective Study

M. Mcdermott, D. Sidransky, S. Ahrendt, 2003 .

Head and neck cancer.

D. Sidransky, W. Koch, A. Trotti, 2001, The New England journal of medicine.

Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer

J. Epstein, D. Sidransky, C. Eisenberger, 2000 .

Two distinct regions of loss on chromosome arm 4q in primary head and neck squamous cell carcinoma.

J. Jen, J. Califano, D. Sidransky, 2000, Archives of otolaryngology--head & neck surgery.

Inverted sinonasal papilloma : a molecular genetic appraisal of its putative status as a Precursor to squamous cell carcinoma.

J. Califano, D. Sidransky, W. Westra, 2000, The American journal of pathology.

Allelotype of posterior uveal melanoma: implications for a bifurcated tumor progression pathway.

D. Sidransky, S. Merbs, P. Parrella, 1999, Cancer Research.

Unknown primary head and neck squamous cell carcinoma: molecular identification of the site of origin.

J. Califano, D. Sidransky, W. Westra, 1999, Journal of the National Cancer Institute.

Molecular methods for the diagnosis of cancer.

D. Sidransky, P. Cairns, 1999, Biochimica et biophysica acta.

Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma.

D. Sidransky, S. Merbs, 1999, Investigative ophthalmology & visual science.

Lack of BRCA2 alterations in primary head and neck squamous cell carcinoma

D. Sidransky, W. Westra, W. Koch, 1998, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

Impact of chromosome 14q loss on survival in primary head and neck squamous cell carcinoma.

J. Califano, D. Sidransky, M. Zahurak, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Gene promoter hypermethylation in tumors and lymph nodes of stage I lung cancer patients.

S. Goodman, D. Sidransky, W. Westra, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells

A. Zhavoronkov, C. Chung, E. Fertig, 2017, Clinical Cancer Research.

Mitochondrial DNA mutations in respiratory complex‐I in never‐smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation

W. Lam, N. Mukhopadhyay, A. Gazdar, 2012, Journal of cellular physiology.

Mitochondrial Subversion in Cancer

A. Chatterjee, D. Sidransky, S. Dasgupta, 2011, Cancer Prevention Research.

Following Mitochondrial Footprints through a Long Mucosal Path to Lung Cancer

R. Yung, D. Sidransky, W. Westra, 2009, PloS one.

Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer.

M. Hoque, D. Sidransky, S. Upadhyay, 2008, Cancer research.

Epigenetic Heterogeneity of High-Grade Prostatic Intraepithelial Neoplasia: Clues for Clonal Progression in Prostate Carcinogenesis

A. Carvalho, M. Hoque, D. Sidransky, 2006, Molecular Cancer Research.

Uncommon mutation, but common amplifications, of the PIK3CA gene in thyroid tumors.

P. Ladenson, Guojun Wu, Zhongmin Guo, 2005, The Journal of clinical endocrinology and metabolism.

Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues.

W. Isaacs, D. Nusskern, D. Sidransky, 1998, Cancer research.

Localization of tumor suppressor loci on chromosome 9 in primary human renal cell carcinomas.

D. Sidransky, Y. Eby, K. Tokino, 1995, Cancer research.

p53 Mutation and MDM2 amplification in human soft tissue sarcomas.

P. Meltzer, K. Kinzler, B. Vogelstein, 1993, Cancer research.

DNA methylation markers in colorectal cancer

David Sidransky, Juna Lee, D. Sidransky, 2010, Cancer and Metastasis Reviews.

Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma.

I. Shih, D. Sidransky, G. Singer, 2003, Journal of the National Cancer Institute.

Epigenetic silencing of HOPX promotes cancer progression in colorectal cancer.

O. Margalit, D. Sidransky, K. Yamashita, 2012, Neoplasia.

Comparative mutational landscape analysis of patient-derived tumour xenografts

Elana J Fertig, Luciane T Kagohara, Mariana Brait, 2017, British Journal of Cancer.

High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma.

J. Bartek, J. Califano, D. Sidransky, 1996, Cancer research.

Rates of p16 (MTS1) mutations in primary tumors with 9p loss.

D. Sidransky, A. Merlo, Y. Eby, 1994, Science.

An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA

S. Goodman, A. Carvalho, J. Califano, 2011, Clinical Cancer Research.

Molecular Analysis of Plasma DNA for the Early Detection of Lung Cancer by Quantitative Methylation-Specific PCR

W. Rom, J. Siegfried, J. Grandis, 2010, Clinical Cancer Research.

JAK3 Variant, Immune Signatures, DNA Methylation, and Social Determinants Linked to Survival Racial Disparities in Head and Neck Cancer Patients

Laura S. Manuel, J. Eshleman, L. Marchionni, 2019, Cancer Prevention Research.

Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer

V. Velculescu, L. Marchionni, E. Fertig, 2014, Epigenetics.

Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene.

W. Franklin, D. Sidransky, R. Gemmill, 1997, Cancer research.

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

J. Herman, J. Jen, D. Sidransky, 1999, Oncogene.

A robust and interpretable gene signature for predicting the lymph node status of primary T1/T2 oral cavity squamous cell carcinoma

A. Pearson, L. Marchionni, D. Sidransky, 2021, International journal of cancer.

Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes

Jayshree Advani, Arun H. Patil, Vishalakshi Nanjappa, 2018, Scientific Reports.

Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer.

J. Califano, D. Sidransky, S. Thiagalingam, 2005, Cancer research.

Somatic mutations of PTEN in glioblastoma multiforme.

J. Bruce, D. Sidransky, R. Parsons, 1997, Cancer research.

Cancer genetics: Two tracks but one race?

D. Sidransky, 1996, Current Biology.

Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients.

J. Jen, J. Califano, D. Sidransky, 2001, Cancer research.

Genetic markers for early detection of lung cancer and outcome measures for response to chemoprevention

Marshall W. Anderson, W. Franklin, D. Sidransky, 1997, Journal of cellular biochemistry. Supplement.

Frequent loss of chromosome 9 in human primary non-small cell lung cancer.

F. Askin, E. Gabrielson, D. Sidransky, 1994, Cancer research.

Inherited p53 gene mutations in breast cancer.

B. Vogelstein, T. Tokino, B. Zehnbauer, 1992, Cancer research.

Profiling the expression pattern of GPI transamidase complex subunits in human cancer

G. Netto, B. Trink, D. Sidransky, 2008, Modern Pathology.

Cigarette smoke induces methylation of the tumor suppressor gene NISCH

W. Rom, M. Hoque, D. Sidransky, 2013, Epigenetics.

Endothelin Receptor Type B Gene Promoter Hypermethylation in Salivary Rinses Is Independently Associated with Risk of Oral Cavity Cancer and Premalignancy

Zhe Zhang, T. Padhya, L. Rolnitzky, 2010, Cancer Prevention Research.

Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer

Guojun Wu, C. Moon, B. Trink, 2008, The Prostate.

Evaluation of Promoter Hypermethylation Detection in Body Fluids as a Screening/Diagnosis Tool for Head and Neck Squamous Cell Carcinoma

Steven S. Chang, S. Goodman, A. Carvalho, 2008, Clinical Cancer Research.

A Promoter Methylation Pattern in the N-Methyl-d-Aspartate Receptor 2B Gene Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma

Keishi Yamashita, David Sidransky, Joseph A Califano, 2007, Clinical Cancer Research.

Quantitative hypermethylation of NMDAR2B in human gastric cancer

C. Moon, Juna Lee, B. Trink, 2007, International journal of cancer.

APromoter Methylation Pattern in the N-Methyl-D-Aspartate Receptor 2 BGene Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma

J. Califano, D. Sidransky, M. Zahurak, 2007 .

Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer.

Qinghua Feng, David Sidransky, Amadou Dem, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection.

S. Goodman, A. Chatterjee, M. Hoque, 2006, Journal of the National Cancer Institute.

N-methyl-D-aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-suppressive activity in human esophageal cancer.

A. Carvalho, C. Moon, M. Hoque, 2006, Cancer research.

Optimal Use of a Panel of Methylation Markers with GSTP1 Hypermethylation in the Diagnosis of Prostate Adenocarcinoma

J. Epstein, D. Sidransky, K. Yamashita, 2004, Clinical Cancer Research.

Quantitative Detection of Promoter Hypermethylation of Multiple Genes in the Tumor, Urine, and Serum DNA of Patients with Renal Cancer

J. Califano, M. Hoque, D. Sidransky, 2004, Cancer Research.

Detection of Promoter Hypermethylation of Multiple Genes in the Tumor and Bronchoalveolar Lavage of Patients with Lung Cancer

C. Moon, Juna Lee, M. Hoque, 2004, Clinical Cancer Research.

Patients with Renal Cancer Multiple Genes in the Tumor , Urine , and Serum DNA of Quantitative Detection of Promoter Hypermethylation of Updated

J. Califano, M. Hoque, D. Sidransky, 2004 .

PUMA in head and neck cancer.

M. Hoque, B. Trink, D. Sidransky, 2003, Cancer letters.

Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.

F. Sato, S. Meltzer, M. Hoque, 2002, Cancer cell.

Methylation status in the promoter region of the human PGP9.5 gene in cancer and normal tissues.

J. Jen, D. Sidransky, O. Caballero, 2001, Cancer letters.

Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions

D. Sidransky, M. Sanchez-Cespedes, K. Okami, 2000, Genes, chromosomes & cancer.

Gene promoter hypermethylation in tumors and serum of head and neck cancer patients.

J. Herman, M. Esteller, J. Jen, 2000, Cancer research.

Advances in Brief Gene Promoter Hypermethylation in Tumors and Serum of Head and Neck Cancer Patients 1

J. Herman, M. Esteller, J. Jen, 2000 .

Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines.

J. Jen, D. Sidransky, S. Wehage, 1999, Cancer letters.

Molecular differential diagnosis of renal carcinoma: from microscopes to microsatellites.

D. Sidransky, G. Steiner, 1996, The American journal of pathology.

Detection of oncogene mutations in sputum precedes diagnosis of lung cancer.

R. Hruban, M. Tockman, D. Sidransky, 1994, Cancer research.

Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors.

K. Kinzler, B. Vogelstein, B. Levin, 1992, Science.

Clonal origin of bladder cancer.

B. Vogelstein, D. Sidransky, A. V. von Eschenbach, 1992, The New England journal of medicine.

The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.

A. Chakravarti, N. Shah, A. Maitra, 2004, Genome research.

YAP1 and COX2 Coordinately Regulate Urothelial Cancer Stem-like Cells.

L. Marchionni, G. Netto, M. Hoque, 2018, Cancer research.

AIS is an oncogene amplified in squamous cell carcinoma.

J. Jen, B. Trink, D. Sidransky, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Genome-wide profiling of non-smoking-related lung cancer cells reveals common RB1 rearrangements associated with histopathologic transformation in EGFR-mutant tumors.

I. Catalá, C. Lázaro, S. Verdura, 2020, Annals of oncology : official journal of the European Society for Medical Oncology.

A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non–Small Cell Lung Cancer and Serum DNA

H. Pass, W. Rom, M. Hoque, 2017, Clinical Cancer Research.

Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer

J. Herman, S. Baylin, M. Brock, 2006, PLoS medicine.

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

K. Kinzler, C. Bettegowda, B. Vogelstein, 2015, Science Translational Medicine.

How to Achieve Therapeutic Response in Erlotinib-Resistant Head and Neck Squamous Cell Carcinoma? New Insights from Stable Isotope Labeling with Amino Acids in Cell Culture-Based Quantitative Tyrosine Phosphoproteomics.

S. Pinto, Vishalakshi Nanjappa, A. Radhakrishnan, 2021, Omics : a journal of integrative biology.

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

J. Manola, J. Califano, D. Sidransky, 2007, The New England journal of medicine.

Molecular alterations in oral cancer between tobacco chewers and smokers using serum proteomics.

Yashwanth Subbannayya, A. Chatterjee, T. Prasad, 2021, Cancer biomarkers : section A of Disease markers.

Decreased Mitochondrial DNA Content in Posttreatment Salivary Rinses from Head and Neck Cancer Patients

A. Carvalho, J. Califano, A. Alberg, 2006, Clinical Cancer Research.

Increased Mitochondrial DNA Content in Saliva Associated with Head and Neck Cancer

A. Carvalho, J. Califano, A. Alberg, 2005, Clinical Cancer Research.

Cold atmospheric plasma treatment selectively targets head and neck squamous cell carcinoma cells

M. Keidar, B. Trink, D. Sidransky, 2014, International journal of molecular medicine.

The incidence of p53 mutations increases with progression of head and neck cancer.

R. Hruban, D. Sidransky, Y. Eby, 1993, Cancer research.

Smokers and Nonsmokers Chromosomal Alterations in Lung Adenocarcinoma from Updated

S. Piantadosi, J. Jen, D. Sidransky, 2001 .

OGDHL Is a Modifier of AKT-Dependent Signaling and NF-κB Function

M. Hoque, D. Sidransky, T. Wu, 2012, PloS one.

The Ras Effector RASSF2 Controls the PAR-4 Tumor Suppressor

L. Hesson, H. Donninger, D. Sidransky, 2010, Molecular and Cellular Biology.

Proteomic analysis of cancer-cell mitochondria

Mukesh Verma, Sudhir Srivastava, Jacob Kagan, 2003, Nature Reviews Cancer.

Characterization of a Human Homologue of Proteolysis-Inducing Factor and Its Role in Cancer Cachexia

J. Jen, D. Sidransky, C. Monitto, 2004, Clinical Cancer Research.

Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-induced-mitochondria-dependent apoptosis

J. Califano, B. Trink, D. Sidransky, 2008, Oncogene.

Mutant p53R175H upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells

V. Rotter, Y. Tabach, S. Madar, 2011, Cell Death and Differentiation.

A novel response element confers p63- and p73-specific activation of the WNT4 promoter.

Y. Nagakawa, Guojun Wu, B. Trink, 2006, Biochemical and biophysical research communications.

Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.

J. Herman, S. Baylin, M. Esteller, 2000, Cancer research.

Promoter Hypermethylation as an Independent Prognostic Factor for Relapse in Patients with Prostate Cancer Following Radical Prostatectomy

A. Partin, J. Epstein, M. Hoque, 2005, Clinical Cancer Research.

Detection of tumor mutations in the presence of excess amounts of normal DNA

D. Sidransky, L. Wu, Xiyuan Sun, 2002, Nature Biotechnology.

Clinical and public health research using methylated DNA Immunoprecipitation (MeDIP): A comparison of commercially available kits to examine differential DNA methylation across the genome

Pamela Leal-Rojas, D. Sidransky, R. Guerrero-Preston, 2012, Epigenetics.

An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine

G. Netto, L. Schultz, M. Hoque, 2014, Oncotarget.

Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

L. Marchionni, M. Hoque, D. Sidransky, 2013, PloS one.

Cysteine Dioxygenase 1 Is a Tumor Suppressor Gene Silenced by Promoter Methylation in Multiple Human Cancers

Juna Lee, D. Sidransky, H. Park, 2012, PloS one.

Pharmacologic Unmasking of Epigenetically Silenced Genes in Breast Cancer

P. Argani, M. Hoque, D. Sidransky, 2009, Clinical Cancer Research.

Aberrant Promoter Methylation of Multiple Genes during Pathogenesis of Bladder Cancer

B. Czerniak, A. Carvalho, M. Hoque, 2008, Cancer Epidemiology Biomarkers & Prevention.

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.

J. Herman, S. Baylin, M. Esteller, 2000, Cancer research.

Frequent microsatellite instability in primary small cell lung cancer.

S. Baylin, E. Gabrielson, E. Gabrielson, 1994, Cancer research.

Changes in CpG Islands Promoter Methylation Patterns during Ductal Breast Carcinoma Progression

M. Copetti, M. Hoque, D. Sidransky, 2009, Cancer Epidemiology, Biomarkers & Prevention.

INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program

D. Sidransky, R. Guerrero-Preston, Fahcina P Lawson, 2017, Molecular medicine reports.

Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer

J. Califano, D. Sidransky, W. Koch, 2013, Oncology reports.

Tissue imprint for molecular mapping of deep surgical margins in patients with head and neck squamous cell carcinoma

J. Roh, J. Califano, D. Sidransky, 2012, Head & neck.

KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses

J. Califano, M. Hoque, D. Sidransky, 2010, International journal of cancer.

DPC4 gene in various tumor types.

Kathleen R. Cho, P. Meltzer, R. Hruban, 1996, Cancer research.

CLINICAL IMPLICATIONS OF THE p 53 GENE

D. Sidransky, D. M., 1996 .

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development.

S. Nomoto, J. Jen, Guojun Wu, 2003, Cancer research.

p53 associates with and targets ΔNp63 into a protein degradation pathway

B. Trink, D. Sidransky, E. Ratovitski, 2001 .

Microsatellite alterations in serum DNA of head and neck cancer patients

David Sidransky, D. Sidransky, W. Koch, 1996, Nature Medicine.

Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice

B. Kolb, O. Kovalchuk, Y. Ilnytskyy, 2017, Oncotarget.

Detection of c-myc amplification in uveal melanoma by fluorescent in situ hybridization.

D. Sidransky, O. Caballero, S. Merbs, 2001, Investigative ophthalmology & visual science.

Silencing of high‐mobility group box 2 (HMGB2) modulates cisplatin and 5‐fluorouracil sensitivity in head and neck squamous cell carcinoma

Nandini A. Sahasrabuddhe, A. Pandey, S. Pinto, 2015, Proteomics.

Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells

B. Trink, D. Sidransky, E. Ratovitski, 2011, Cell Death and Differentiation.

High-throughput molecular analysis of urine sediment for the detection of bladder cancer by high-density single-nucleotide polymorphism array.

Keishi Yamashita, David Sidransky, Juna Lee, 2003, Cancer research.

Molecular detection of genetic alterations in the serum of colorectal cancer patients.

J. Jen, D. Sidransky, L. Wu, 1998, Cancer research.

A comparison between microsatellite and quantitative PCR analyses to detect frequent p16 copy number changes in primary bladder tumors.

J. Cairns, D. Sidransky, S. Ramamoorthy, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Screening for clonal genetic alterations.

D. Sidransky, 1995, European journal of cancer.

Human AQP5 Plays a Role in the Progression of Chronic Myelogenous Leukemia (CML)

C. Moon, Juna Lee, D. Sidransky, 2008, PloS one.

p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma.

S. Goodman, D. Sidransky, M. Zahurak, 1996, Journal of the National Cancer Institute.

Overexpression of c-met as a prognostic indicator for transitional cell carcinoma of the urinary bladder: a comparison with p53 nuclear accumulation.

Chung-Liang Ho, B. Trink, D. Sidransky, 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Patient-derived xenografts for individualized care in advanced sarcoma

David Sidransky, Robert Maki, R. Maki, 2014, Cancer.

The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation

J. Califano, D. Sidransky, Q. Tao, 2007, Oncogene.

ΔNp63 induces β-catenin nuclear accumulation and signaling

S. Nomoto, J. Califano, B. Trink, 2002 .

Normal polymorphism in the incomplete trinucleotide repeat of the arginine-rich protein gene.

D. Sidransky, S. Ahrendt, N. Halachmi, 1997, Cancer research.

Re: Is TIG1 a new tumor suppressor in prostate cancer?

S. Nomoto, D. Sidransky, K. Yamashita, 2003, Journal of the National Cancer Institute.

Epigenetic inactivation of VGF associated with Urothelial Cell Carcinoma and its potential as a non-invasive biomarker using urine

G. Netto, M. Hoque, D. Sidransky, 2014, Oncotarget.

Molecular Profiling Associated with Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)-Mediated Carcinogenesis in Gastric Cancer.

A. Chatterjee, T. Prasad, H. Gowda, 2021, Journal of proteome research.

I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma.

D. Sidransky, C. Lopes, G. Varzim, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive p53 Gene Mutations in Squamous Cell Carcinoma of the Head and Neck

J. Taube, D. Sidransky, W. Westra, 2008, Clinical Cancer Research.

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma

L. Cope, G. Netto, M. Hoque, 2013, Cell cycle.

p53 and p21(WAF1/CIP1/SDI1) gene products in Barrett esophagus and adenocarcinoma of the esophagus and esophagogastric junction.

C. Moskaluk, D. Sidransky, M. Zahurak, 1996, Human pathology.

ATM kinase is a master switch for the ΔNp63α phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

Yiping Huang, David Sidransky, B. Trink, 2008 .

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer.

P. Ladenson, J. Califano, D. Sidransky, 2005, The Journal of clinical endocrinology and metabolism.

DeltaNp63alpha up-regulates the Hsp70 gene in human cancer.

Guojun Wu, Zhongmin Guo, J. Califano, 2005, Cancer research.

Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer.

T. Rebbeck, A. Gazdar, S. Powell, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Allelotype of head and neck squamous cell carcinoma.

R. Hruban, D. Sidransky, W. Koch, 1994, Cancer research.

Genetic divergence in the clonal evolution of breast cancer.

E Gabrielson, E. Gabrielson, D. Sidransky, 1996, Cancer research.

An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation

S. Tabak, M. Hoque, D. Sidransky, 2015, Scientific Reports.

Diagnosis of Renal Cancer by Molecular Urinalysis

F. Marshall, D. Sidransky, C. Eisenberger, 1999 .

Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker.

M. Hoque, D. Sidransky, C. Lopes, 2004, Clinical cancer research : an official journal of the American Association for Cancer Research.

Progression of microsatellite instability from premalignant lesions to tumors of the head and neck

J. Califano, D. Sidransky, W. Westra, 2002, International journal of cancer.

Cigarette smoking is strongly associated with mutation of the K‐ras gene in patients with primary adenocarcinoma of the lung

D. Sidransky, S. Ahrendt, Stephen C. Yang, 2001, Cancer.

Quantitative hypermethylation of a small panel of genes augments the diagnostic accuracy in fine-needle aspirate washings of breast lesions

Paula Monteiro, Rui Henrique, David Sidransky, 2008, Breast Cancer Research and Treatment.

Patient‐derived xenografts as tools in pharmaceutical development

M. Hoque, D. Sidransky, E. Izumchenko, 2016, Clinical pharmacology and therapeutics.

Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance

A. Chatterjee, D. Sidransky, C. Monitto, 2012, Cell cycle.

Whole-Exome Sequencing Analysis of Oral Squamous Cell Carcinoma Delineated by Tobacco Usage Habits

A. Chatterjee, H. Gowda, D. Sidransky, 2021, Frontiers in Oncology.

R. Biggar, D. Sidransky, G. Bedi, 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.

Early Occurrence of RASSF1A Hypermethylation and Its Mutual Exclusion with BRAF Mutation in Thyroid Tumorigenesis

Yoram Cohen, Giovanni Tallini, David Sidransky, 2004, Cancer Research.

The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.

D. Sidransky, G. Singer, S. Dong, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

The RASSF 1 A Tumor Suppressor Gene Is Commonly Inactivated in Adenocarcinoma of the Uterine Cervix

D. Sidransky, G. Singer, S. Dong, 2003 .

LKB1 protein expression in the evolution of glandular neoplasia of the lung.

D. Sidransky, M. Zahurak, W. Westra, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

High Promoter Methylation Levels of APC Predict Poor Prognosis in Sextant Biopsies from Prostate Cancer Patients

A. Carvalho, M. Hoque, D. Sidransky, 2007, Clinical Cancer Research.

Proteomic and phosphoproteomic profiling of shammah induced signaling in oral keratinocytes

Jayshree Advani, Tejaswini Subbannayya, K. Datta, 2021, Scientific Reports.

Squamous cell carcinoma of the head and neck in the elderly.

D. Sidransky, W. Koch, J. Brennan, 1995, Archives of otolaryngology--head & neck surgery.

Gene mutations in saliva as molecular markers for head and neck squamous cell carcinomas.

D. Sidransky, W. Koch, L. Mao, 1994, American journal of surgery.

MT1G Hypermethylation Is Associated with Higher Tumor Stage in Prostate Cancer

Rui Henrique, Carmen Jerónimo, David Sidransky, 2005, Cancer Epidemiology Biomarkers & Prevention.

Hypermethylation Is Associated with Higher Tumor Stage in Prostate Cancer

S. Nomoto, A. Carvalho, M. Hoque, 2005 .

The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors.

M. Hoque, D. Sidransky, E. Izumchenko, 2014, Cancer research.

Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates.

E Gabrielson, M Fliss, E. Gabrielson, 2001, Cancer research.

Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer

M. Hoque, D. Sidransky, M. Zahurak, 2012, Epigenetics.

A new human p53 homologue

J. Jen, B. Trink, D. Sidransky, 1998, Nature Medicine.

Molecular screening--how long can we afford to wait?

D. Sidransky, 1994, Journal of the National Cancer Institute.

Tumor Protein p63/Nuclear Factor κB Feedback Loop in Regulation of Cell Death*

D. Sidransky, Yiping Huang, E. Ratovitski, 2011, The Journal of Biological Chemistry.

ΔNp63α Levels Correlate with Clinical Tumor Response to Cisplatin

D. Sidransky, E. Ratovitski, R. Zangen, 2005 .

RACK1 and Stratifin Target ΔNp63α for a Proteasome Degradation in Head and Neck Squamous Cell Carcinoma Cells upon DNA Damage

Zhongmin Guo, B. Trink, D. Sidransky, 2004 .

Distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma.

J. Jen, D. Sidransky, W. Westra, 1998, Journal of the National Cancer Institute.

Fluorescence Visualization in Oral Neoplasia: Shedding Light on an Old Problem

David Sidransky, D. Sidransky, W. Westra, 2006, Clinical Cancer Research.

Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation.

J. Califano, D. Sidransky, M. Zahurak, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Allelic losses in OraTest-directed biopsies of patients with prior upper aerodigestive tract malignancy.

D. Sidransky, W. Westra, W. Koch, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Serial analysis of gene expression in non-small cell lung cancer.

J. Jen, D. Sidransky, S. Madden, 1998, Cancer research.

Microsatellite instability in primary neoplasms from HIV+ patients

H. Farzadegan, D. Sidransky, W. Westra, 1995, Nature Medicine.

First on March 9 , 2010 as 10 . 1158 / 0008-5472 . CAN-09-3427

Steven S. Chang, J. Califano, D. Sidransky, 2010 .

HOP/OB1/NECC1 Promoter DNA Is Frequently Hypermethylated and Involved in Tumorigenic Ability in Esophageal Squamous Cell Carcinoma

D. Sidransky, M. Mori, M. Osada, 2008, Molecular Cancer Research.

PGP9.5 methylation in diffuse-type gastric cancer.

D. Sidransky, M. Mori, M. Osada, 2006, Cancer research.

Biomarkers for Lung Cancer Screening and Detection

S. Hanash, A. Spira, D. Sidransky, 2020, Cancer Epidemiology, Biomarkers & Prevention.

Mouse mammary tumor‐like env gene as a molecular marker for breast cancer?

D. Sidransky, S. Harden, P. Parrella, 2002, International journal of cancer.

Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks.

Alexander V. Favorov, Daria A. Gaykalova, Bahman Afsari, 2017, Cancer research.

LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.

Guojun Wu, Zhongmin Guo, B. Trink, 2007, Cancer research.

Performance of mitochondrial DNA mutations detecting early stage cancer

A. Maitra, W. Rom, M. Hoque, 2008, BMC Cancer.

Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck

A. Maitra, A. Chatterjee, Guojun Wu, 2007, Proceedings of the National Academy of Sciences.

An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome.

D. Cutler, A. Maitra, G. Kennedy, 2006, The Journal of molecular diagnostics : JMD.

Mitochondrial mutations in early stage prostate cancer and bodily fluids

S. Nomoto, D. Sidransky, O. Caballero, 2001, Oncogene.

LKB1/STK11 suppresses cyclooxygenase-2 induction and cellular invasion through PEA3 in lung cancer.

A. Chatterjee, M. Hoque, B. Trink, 2006, Cancer research.

Hyperactivation of MEK/ERK pathway by Ca2+/calmodulin‐dependent protein kinase kinase 2 promotes cellular proliferation by activating cyclin‐dependent kinases and minichromosome maintenance protein in gastric cancer cells

A. Chatterjee, H. Gowda, D. Sidransky, 2021, Molecular carcinogenesis.

The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors

S. Goodman, I. Wistuba, M. Hidalgo, 2013, PloS one.

A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma

Nandini A. Sahasrabuddhe, A. Pandey, S. Pinto, 2016, Scientific Reports.

Inhibition of TGF-β Enhances the In Vivo Antitumor Efficacy of EGF Receptor–Targeted Therapy

C. Chung, E. Fertig, J. Califano, 2012, Molecular Cancer Therapeutics.

Words matter: distinguishing "personalized medicine" and "biologically personalized therapeutics".

M. Piccart, A. Gabizon, E. D. de Vries, 2014, Journal of the National Cancer Institute.

Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds

D. Sidransky, L. Goldman, B. Apelberg, 2010, Epigenetics.

The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth

C. Moon, B. Trink, D. Sidransky, 2008, Oncogene.

RET proto-oncogene mutations in inherited and sporadic medullary thyroid cancer.

S. Baylin, R. Hruban, D. Sidransky, 1994, Human molecular genetics.

PD-L1 Expression in the Merkel Cell Carcinoma Microenvironment: Association with Inflammation, Merkel Cell Polyomavirus, and Overall Survival

J. Taube, E. Lipson, D. Sidransky, 2013, Cancer Immunology Research.

Inhibitors EMT-Associated Kinase Switch That Induces Resistance to EGFR MIG 6 Pathway Orchestrates the − miR 200 − β The TGF

M. Hoque, D. Sidransky, E. Izumchenko, 2014 .

Feasibility of quantitative PCR‐based saliva rinse screening of HPV for head and neck cancer

A. Carvalho, J. Califano, D. Sidransky, 2005, International journal of cancer.

Corrigendum: A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma

Nandini A. Sahasrabuddhe, A. Pandey, S. Pinto, 2017, Scientific Reports.

Detecting cervical cancer by quantitative promoter hypermethylation assay on cervical scrapings: a feasibility study.

Yoram Cohen, David Sidransky, H. Boezen, 2004, Molecular cancer research : MCR.

Ranpirnase Eradicates Human Papillomavirus in Cultured Cells and Heals Anogenital Warts in a Phase I Study

T. Hodge, D. Sidransky, S. Brendle, 2017, Antiviral therapy.

p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma.

J. Roh, J. Califano, D. Sidransky, 2011, Oral oncology.

Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile

Nandini A. Sahasrabuddhe, A. Pandey, Tejaswini Subbannayya, 2014, Future oncology.

Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer.

M. Brock, J. Califano, D. Sidransky, 2007, Lung cancer.

Precision health diagnostic and surveillance network uses S gene target failure (SGTF) combined with sequencing technologies to track emerging SARS‐CoV‐2 variants

L. Marchionni, D. Sidransky, M. Mackay, 2021, medRxiv.

BORIS Binding to the Promoters of Cancer Testis Antigens, MAGEA2, MAGEA3, and MAGEA4, Is Associated with Their Transcriptional Activation in Lung Cancer

Daria A. Gaykalova, J. Califano, D. Sidransky, 2011, Clinical Cancer Research.

Dose-Dependent Activation of Putative Oncogene SBSN by BORIS

Daria A. Gaykalova, R. Vatapalli, J. Califano, 2012, PloS one.

Correction: OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation

Jun Yu, J. Rhim, D. Sidransky, 2008, PLoS ONE.

OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation

Jun Yu, J. Rhim, D. Sidransky, 2008, PloS one.

Common pathway signature in lung and liver fibrosis

Anthony Atala, Alex Zhavoronkov, Anton Buzdin, 2016, Cell cycle.

Differential promoter methylation of kinesin family member 1a in plasma is associated with breast cancer and DNA repair capacity

Luisa Mola Morales, D. Sidransky, R. Guerrero-Preston, 2014, Oncology reports.

COMMENT ON : DISTINGUISHING SECOND PRIMARY TUMORS FROM LUNG METASTASES IN PATIENTS WITH HEAD AND NECK SQUAMOUS CELL CARCINOMA. AUTHORS' REPLY

J. Jen, P. Harari, D. Sidransky, 1998 .

Alteration of Cellular and Humoral Immunity by Mutant p53 Protein and Processed Mutant Peptide in Head and Neck Cancer

E. Jaffee, H. Erlich, R. Ferris, 2007, Clinical Cancer Research.

Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer.

J. Jen, J. Califano, D. Sidransky, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence.

J. Herman, M. Esteller, S. Piantadosi, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Mitochondrial DNA as a cancer biomarker.

A. Maitra, D. Sidransky, M. Coble, 2005, The Journal of molecular diagnostics : JMD.

Tumor‐specific changes in mtDNA content in human cancer

S. Sukumar, A. Chatterjee, D. Sidransky, 2005, International journal of cancer.

Milk derived colloid as a novel drug delivery carrier for breast cancer

D. Sidransky, W. Koch, R. Ravi, 2015, Cancer biology & therapy.

Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer.

J. Epstein, D. Sidransky, C. Eisenberger, 1999, International journal of cancer.

Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy

A. Zhavoronkov, L. Marchionni, D. Sidransky, 2018, Nature Communications.

The KRAS-Variant and Cetuximab Response in Head and Neck Squamous Cell Cancer: A Secondary Analysis of a Randomized Clinical Trial

Anurag K. Singh, J. Weidhaas, C. Chung, 2017, JAMA oncology.

Role of protein kinase N2 (PKN2) in cigarette smoke-mediated oncogenic transformation of oral cells

Arun H. Patil, Vishalakshi Nanjappa, P. Rajagopalan, 2018, Journal of Cell Communication and Signaling.

p63α Mutations Lead to Aberrant Splicing of Keratinocyte Growth Factor Receptor in the Hay-Wells Syndrome*

B. Trink, D. Sidransky, Yiping Huang, 2003, Journal of Biological Chemistry.

Microsatellite instability at selected tetranucleotide repeats is associated with p53 mutations in non-small cell lung cancer.

J. Jen, D. Sidransky, S. Ahrendt, 2000, Cancer research.

Prognostic biomarkers in patients with human immunodeficiency virus‐positive disease with head and neck squamous cell carcinoma

Amy Y. Chen, G. Sica, J. Lee, 2017, Head & neck.

KRAS Mutation Status Is Associated with Enhanced Dependency on Folate Metabolism Pathways in Non–Small Cell Lung Cancer Cells

D. Sidransky, S. Bacus, K. Paz, 2014, Molecular Cancer Therapeutics.

TAp63γ regulates hOGG1 and repair of oxidative damage in cancer cell lines

A. Chatterjee, B. Trink, D. Sidransky, 2007 .

Microsatellite instability at AAAG repeat sequences in respiratory tract cancers

M. Tockman, S. Piantadosi, J. Jen, 2001, International journal of cancer.

ΔNp63&alpha Overexpression Induces Downregulation of Sirt1 and an Accelerated Aging Phenotype in the Mouse

L. Donehower, D. Sidransky, S. Upadhyay, 2006, Cell cycle.

ΔNp63α and TAp63α regulate transcription of genes with distinct biological functions in cancer and development

S. Nomoto, J. Jen, Guojun Wu, 2003 .

Advances in Brief Np 63 and TAp 63 Regulate Transcription of Genes with Distinct Biological Functions in Cancer and Development 1

S. Nomoto, J. Jen, Guojun Wu, 2003 .

p63 Transcriptional Regulation of Epithelial Integrity and Cancer

David Sidransky, B. Trink, D. Sidransky, 2007, Cell cycle.

p63-specific activation of the BPAG-1e promoter.

Y. Nagakawa, Guojun Wu, B. Trink, 2005, The Journal of investigative dermatology.

Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing.

P. Ladenson, Zhongmin Guo, J. Califano, 2003, Cancer research.

DeltaNp63alpha levels correlate with clinical tumor response to cisplatin.

D. Sidransky, E. Ratovitski, R. Zangen, 2005, Cell cycle.

Molecular alterations associated with chronic exposure to cigarette smoke and chewing tobacco in normal oral keratinocytes

Vishalakshi Nanjappa, Tejaswini Subbannayya, K. Datta, 2017, Cancer biology & therapy.

Establishment and characterization of a platinum- and paclitaxel-resistant high grade serous ovarian carcinoma cell line

T. Conrads, D. Sidransky, B. Hood, 2017, Human Cell.

Microsatellite‐based cancer detection using capillary array electrophoresis and energy‐transfer fluorescent primers

R. Mathies, D. Sidransky, A. Glazer, 1997, Electrophoresis.

Biallelic inactivation of the RIZ1 gene in human gastric cancer

S. Nomoto, B. Trink, D. Sidransky, 2003, Oncogene.

Session 2: Molecular Diagnostics

D. Sidransky, 2004 .

Secretome analysis of oral keratinocytes chronically exposed to shisha.

Jayshree Advani, Tejaswini Subbannayya, G. Sathe, 2019, Cancer biomarkers : section A of Disease markers.

The role of PGP9.5 as a tumor suppressor gene in human cancer

D. Sidransky, M. Mori, M. Osada, 2008, International journal of cancer.

PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma.

Yoichi Tanaka, Keishi Yamashita, David Sidransky, 2005, Cancer research.

Promoter Methylation Is an Independent Prognostic Factor for Esophageal Squamous Cell Carcinoma

K. Mimori, Yoichi Tanaka, A. Carvalho, 2005 .

Molecular alterations in oral cancer using high-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue

S. Pinto, K. Datta, Yashwanth Subbannayya, 2021, Journal of Cell Communication and Signaling.

Molecular techniques and genetic alterations in head and neck cancer.

Steven S. Chang, J. Califano, D. Sidransky, 2009, Oral oncology.

Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer.

J. Herman, M. Esteller, J. Jen, 1999, Journal of the National Cancer Institute.

Distal nephron renal tumors: microsatellite allelotype.

F. Marshall, J. Epstein, T. Polascik, 1996, Cancer research.

MicroRNA alterations in head and neck squamous cell carcinoma

David Sidransky, Steven S. Chang, J. Califano, 2008, International journal of cancer.

Correction: Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression

L. Marchionni, M. Hoque, D. Sidransky, 2013, PLoS ONE.

Investigation of curcumin-mediated signalling pathways in head and neck squamous cell carcinoma

Arun H. Patil, Vishalakshi Nanjappa, Tejaswini Subbannayya, 2017 .

Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta.

A. Chatterjee, D. Sidransky, R. Ravi, 2010, Cancer research.

Tissue and Cell-Free DNA-Based Epigenomic Approaches for Cancer Detection.

D. Sidransky, M. Brait, A. Leal, 2019, Clinical chemistry.

Cigarette smoke induces promoter methylation of single‐stranded DNA‐binding protein 2 in human esophageal squamous cell carcinoma

J. Califano, Juna Lee, D. Sidransky, 2011, International journal of cancer.

Association between Lifestyle Factors and CpG Island Methylation in a Cancer-Free Population

Mariana Brait, David Sidransky, Jean G. Ford, 2009, Cancer Epidemiology, Biomarkers & Prevention.

Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice

B. Kolb, O. Kovalchuk, Y. Ilnytskyy, 2017, Aging.

Absence of TSG101 transcript abnormalities in human cancers

S. Sukumar, J. Jen, E. Gabrielson, 1998, Oncogene.

Detection of Methylated CDO1 in Plasma of Colorectal Cancer; A PCR Study

D. Sidransky, K. Yamashita, M. Kim, 2014, PloS one.

A Quantitative Promoter Methylation Profile of Prostate Cancer

M. Hoque, D. Sidransky, C. Lopes, 2004, Clinical Cancer Research.

Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma

A. Pearson, A. Zhavoronkov, Michael Korzinkin, 2021, Frontiers in Oncology.

LOXL 1 and LOXL 4 Are Epigenetically Silenced and Can Inhibit Ras / Extracellular Signal-Regulated Kinase Signaling Pathway in Human Bladder Cancer

Guojun Wu, Zhongmin Guo, B. Trink, 2007 .

Clinical Correlates of Promoter Hypermethylation of Four Target Genes in Head and Neck Cancer: A Cooperative Group Correlative Study

J. Manola, J. Roh, D. Sidransky, 2013, Clinical Cancer Research.

The Oral Cavity as a Molecular Mirror of Lung Carcinogenesis

David Sidransky, D. Sidransky, 2008, Cancer Prevention Research.

p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways.

V. Rotter, S. Madar, R. Brosh, 2010, Cancer research.

Molecular screening. Prospects for a new approach.

D. Sidransky, W. Koch, J. Boyle, 1993, Archives of otolaryngology--head & neck surgery.

Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.

D. Sidransky, M. Schoenberg, S. Docimo, 1999, Urology.

Molecular markers of radiation effectiveness in head and neck squamous cell carcinoma.

D. Sidransky, W. Koch, 2004, Seminars in radiation oncology.

Chronic shisha exposure alters phosphoproteome of oral keratinocytes

Jayshree Advani, Tejaswini Subbannayya, G. Sathe, 2019, Journal of Cell Communication and Signaling.

Genomic organization and mutation analysis of Hel-N1 in lung cancers with chromosome 9p21 deletions.

J. Jen, D. Sidransky, S. Ahrendt, 1997, Cancer research.

Paired Box 5 Methylation Detection by Droplet Digital PCR for Ultra-Sensitive Deep Surgical Margins Analysis of Head and Neck Squamous Cell Carcinoma

D. Sidransky, R. Guerrero-Preston, W. Koch, 2015, Cancer Prevention Research.

The Ligamp TP53 Assay for Detection of Minimal Residual Disease in Head and Neck Squamous Cell Carcinoma Surgical Margins

J. Manola, J. Califano, D. Sidransky, 2009, Clinical Cancer Research.

A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma

J. Califano, M. Hoque, D. Sidransky, 2011, International journal of cancer.

Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma.

D. Sidransky, K. Yamashita, M. Kim, 2011, International journal of oncology.

Advancing toward a molecular characterization of polymorphous low grade adenocarcinoma.

D. Sidransky, W. Westra, M. Brait, 2017, Oral oncology.

Mitochondrial DNA alterations in thyroid cancer

J. Califano, D. Sidransky, W. Westra, 2003, Journal of surgical oncology.

AIM1 promoter hypermethylation as a predictor of decreased risk of recurrence following radical prostatectomy

A. Partin, J. Epstein, M. Hoque, 2012, The Prostate.

Potential utility of HOP homeobox gene promoter methylation as a marker of tumor aggressiveness in gastric cancer

D. Sidransky, K. Yamashita, M. Kim, 2010, Oncogene.

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

E. Montgomery, J. Eshleman, A. Maitra, 2006, Molecular Cancer.

Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells

Nandini A. Sahasrabuddhe, A. Pandey, S. Renuse, 2016, Oncotarget.

Chronic exposure to chewing tobacco selects for overexpression of stearoyl-CoA desaturase in normal oral keratinocytes

Nandini A. Sahasrabuddhe, A. Pandey, S. Renuse, 2015, Cancer biology & therapy.

Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma

Bhuvanesh Singh, J. Califano, D. Sidransky, 2003, International journal of cancer.

Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma.

D. Sidransky, K. Yamashita, M. Kim, 2011, International journal of oncology.

Developing Oncology Drugs Using Virtual Patients of Vascular Tumor Diseases

Z. Agur, D. Sidransky, Y. Kogan, 2011 .

Frequent 14-3-3 sigma promoter methylation in benign and malignant prostate lesions.

A. Carvalho, M. Hoque, D. Sidransky, 2005, DNA and cell biology.

Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast Cancer

D. Sidransky, K. Yamashita, A. Ema, 2016, PloS one.

Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure.

B. Trink, D. Sidransky, S. Sinha, 2010, Cell cycle.

Long-Term Cigarette Smoke Exposure and Changes in MiRNA Expression and Proteome in Non-Small-Cell Lung Cancer.

T S Keshava Prasad, Jayshree Advani, Yashwanth Subbannayya, 2017, Omics : a journal of integrative biology.

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment

D. Sidransky, W. Westra, R. Guerrero-Preston, 2016, Oncotarget.

CEBP FOCUS Biomarkers for Lung Cancer Screening and Detection

S. Hanash, A. Spira, D. Sidransky, 2020 .

Microsatellite analysis of 9p2i in primary uveal melanoma

J. Jen, W. Green, D. Sidransky, 1997 .

Tissue inhibitor of metalloproteinases-3 promoter methylation is an independent prognostic factor for bladder cancer.

S. Goodman, B. Trock, M. Hoque, 2008, The Journal of urology.

Colon cancer genetics

B. Vogelstein, C. Boland, T. Smyrk, 1992, Cancer.

Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations

Zhongmin Guo, D. Sidransky, E. Mambo, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Genetic and Epigenetic Analysis of erbB Signaling Pathway Genes in Lung Cancer

Mariana Brait, David Sidransky, M. Hoque, 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

I 105 V Polymorphism and Promoter Methylation of the GSTP 1 Gene in Prostate Adenocarcinoma 1

D. Sidransky, C. Lopes, G. Varzim, 2002 .

Adenylate Kinase 3 Sensitizes Cells to Cigarette Smoke Condensate Vapor Induced Cisplatin Resistance

A. Chatterjee, D. Sidransky, R. Ravi, 2011, PloS one.

Advances in Brief Microsatellite instability in Bladder Cancer I

Peter A. Jones, D. Sidransky, K. Tokino, 2007 .

Signaling alterations in oral keratinocytes in response to shisha and crude tobacco extract.

Jayshree Advani, Tejaswini Subbannayya, K. Datta, 2020, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Prenatal exposure to tobacco smoke leads to increased mitochondrial DNA content in umbilical cord serum associated to reduced gestational age

D. Sidransky, L. Goldman, F. Witter, 2017, International journal of environmental health research.

Quantitative RARβ2 Hypermethylation

M. Hoque, D. Sidransky, C. Lopes, 2004, Clinical Cancer Research.

U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of ΔNp63α

A. Chatterjee, B. Trink, D. Sidransky, 2008 .

miRNA profiling of bladder cells chronically exposed to cigarette smoke condensate and its vapor

Jayshree Advani, A. Chatterjee, T. Prasad, 2017 .

Mitochondrial DNA Content Increase in Response to Cigarette Smoking

J. Califano, A. Alberg, D. Sidransky, 2006, Cancer Epidemiology Biomarkers & Prevention.

Cancer Biology and Signal Transduction KRAS Mutation Status Is Associated with Enhanced Dependency on Folate Metabolism Pathways in Non – Small Cell Lung Cancer Cells

D. Sidransky, S. Bacus, K. Paz, 2014 .

ssDNA-Binding Protein 2 Is Frequently Hypermethylated and Suppresses Cell Growth in Human Prostate Cancer

J. Califano, C. Moon, Juna Lee, 2008, Clinical Cancer Research.

Testican 1 (SPOCK1) and protein tyrosine phosphatase, receptor type S (PTPRS) show significant increase in saliva of tobacco users with oral cancer

A. Pandey, S. Renuse, Arun H. Patil, 2018 .

Involvement of Epigenetics and EMT-Related miRNA in Arsenic-Induced Neoplastic Transformation and Their Potential Clinical Use

H. Ahsan, G. Netto, M. Hoque, 2015, Cancer Prevention Research.

Hypermethylation of Genes Detected in Urine from Ghanaian Adults with Bladder Pathology Associated with Schistosoma haematobium Infection

C. Shiff, M. Hoque, D. Sidransky, 2013, PloS one.

Repurposing the FDA-Approved Antiviral Drug Ribavirin as Targeted Therapy for Nasopharyngeal Carcinoma

D. Sidransky, T. Zhao, H. Brem, 2020, Molecular Cancer Therapeutics.

miRNA and Proteomic Dysregulation in Non-Small Cell Lung Cancer in Response to Cigarette Smoke.

Nandini A. Sahasrabuddhe, Jayshree Advani, A. Radhakrishnan, 2018, MicroRNA.

A transcriptional progression model for head and neck cancer.

J. Califano, D. Sidransky, M. Zahurak, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Correction: Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor

Daria A. Gaykalova, Nandini A. Sahasrabuddhe, A. Zhavoronkov, 2021, Oncoscience.

Colorectal Cancer Patients Molecular Detection of Genetic Alterations in the Serum of Updated

J. Jen, D. Sidransky, Li Wu, 2006 .

Yes-associated protein 1 regulates the stability of ΔNp63α

A. Chatterjee, D. Sidransky, Xiaofei Chang, 2010 .

Yes-associated protein 1 regulates the stability of DeltaNp63alpha.

A. Chatterjee, D. Sidransky, Xiaofei Chang, 2010, Cell Cycle.

Detection of Promoter Hypermethylation in Salivary Rinses as a Biomarker for Head and Neck Squamous Cell Carcinoma Surveillance

Steven S. Chang, A. Carvalho, J. Califano, 2011, Clinical Cancer Research.

Chronic Exposure to Chewing Tobacco Induces Metabolic Reprogramming and Cancer Stem Cell-Like Properties in Esophageal Epithelial Cells

Vishalakshi Nanjappa, K. Datta, P. Rajagopalan, 2019, Cells.

NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis

D. Sidransky, R. Mehra, E. Golemis, 2017, Nature Communications.

Prevalence of BRAF Mutations in Thyroid Cancer: Genetic Evidence for Constitutive Activation of the RET/ PTC-RAS-BRAF Signaling Pathway in Papillary Thyroid Carci

D. Sidransky, 2017 .

High-performance detection of somatic D-loop mutation in urothelial cell carcinoma patients by polymorphism ratio sequencing

R. Mathies, D. Theodorescu, M. Hoque, 2016, Journal of Molecular Medicine.

Identification of potential biomarkers of head and neck squamous cell carcinoma using iTRAQ based quantitative proteomic approach

Jayshree Advani, S. Renuse, Vishalakshi Nanjappa, 2018, Data in brief.

Basal cell carcinoma-like epidermal changes overlying dermatofibromas often reveal loss of heterozygosity in the PTCH gene.

D. Sidransky, C. Jerónimo, P. Leong, 1999, The Journal of investigative dermatology.

Mutational activation of BRAF is not a major event in sporadic childhood papillary thyroid carcinoma

D. Sidransky, M. Zahurak, W. Westra, 2005, Modern Pathology.

Changes in CpG islands methylation patterns during ductal breast carcinoma progression.

M. Hoque, D. Sidransky, S. Tommasi, 2008 .

Microsatellite Instability in Colorectal Cancer Development of International Criteria for the Determination of Instability for Cancer Detection and Familial Predisposition : A National Cancer Institute Workshop on Microsatellite

Riccardo, Stephen, Boland, 2006 .

Diagnosis of renal cancer by molecular urinalysis.

F. Marshall, D. Sidransky, C. Eisenberger, 1999, Journal of the National Cancer Institute.

Molecular Profiling of Malignant Pleural Effusion in Metastatic Non‐Small‐Cell Lung Carcinoma. The Effect of Preanalytical Factors

D. Ettinger, D. Feller-Kopman, D. Sidransky, 2017, Annals of the American Thoracic Society.

Two tracks but one race? Cancer genetics.

D. Sidransky, 1996, Current Biology.

Molecular genetics of head and neck cancer

D. Sidransky, 1995, Current opinion in oncology.

High-density mapping of chromosomal arm 1q in renal collecting duct carcinoma: region of minimal deletion at 1q32.1-32.2.

F. Marshall, J. Epstein, T. Polascik, 1996, Cancer research.

Notch1 Mutations Are Drivers of Oral Tumorigenesis

David R. Riley, Samuel V. Angiuoli, V. Velculescu, 2014, Cancer Prevention Research.

High-resolution microbiome profiling uncovers Fusobacterium nucleatum, Lactobacillus gasseri/johnsonii, and Lactobacillus vaginalis associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surgery and chemo-radiation

L. Marchionni, J. White, D. Sidransky, 2017, Oncotarget.

Clusterin Is a Gene-Specific Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma

Steven S. Chang, J. Califano, D. Sidransky, 2013, Clinical Cancer Research.

Clusterin Is a Gene-Speci fi c Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma

Steven S. Chang, J. Califano, D. Sidransky, 2014 .

Molecular Analysis of Peritoneal Fluid in Ovarian Cancer Patients

D. Sidransky, T. Nicol, P. Parrella, 2003, Modern Pathology.

Proteomic Alterations Associated with Oral Cancer Patients with Tobacco Using Habits.

Jayshree Advani, K. Datta, A. Chatterjee, 2021, Omics : a journal of integrative biology.

Clinical and Prognostic Significance of the Eighth Edition Oral Cancer Staging System

A. Nashef, D. Sidransky, W. Koch, 2022, Cancers.

ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage.

Yiping Huang, Jatin Nagpal, David Sidransky, 2008, Cell cycle.

Molecular Characterization of Esophageal Squamous Cell Carcinoma Using Quantitative Proteomics

A. Chatterjee, H. Gowda, D. Sidransky, 2023, Cancers.

An accelerated pathway for targeted cancer therapies

S. Friend, R. Schilsky, J. Benner, 2011, Nature Reviews Drug Discovery.

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, Human Papilloma Virus infection and surgical treatment

Thangavel, D. Sidransky, W. Westra, 2016 .

Unexpected heterogeneity in oropharyngeal squamous cell tumors

D. Sidransky, E. Izumchenko, David J. Peace, 2023, Nature Genetics.

MDA-9/Syntenin regulates differentiation and angiogenesis programs in head and neck squamous cell carcinoma

P. Fisher, O. J. Semmes, D. Troyer, 2014, Oncoscience.

Epigenetic Silencing of HOPX Promotes Cancer Progression

O. Margalit, D. Sidransky, K. Yamashita, 2012 .

RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage.

Zhongmin Guo, B. Trink, D. Sidransky, 2004, Cell cycle.

A Novel Class of Ribosome Modulating Agents Exploits Cancer Ribosome Heterogeneity to Selectively Target the CMS2 Subtype of Colorectal Cancer

D. Sidransky, V. Badarinarayana, V. Modur, 2023, Cancer research communications.

Mouse clinical trials of pancreatic cancer: Integration of PDX models with genomics to improve patient outcomes to chemotherapeutics

M. Hidalgo, D. Sidransky, J. Stebbing, 2016 .

Cancer epigenetics: above and beyond

D. Sidransky, M. Brait, 2011 .

Epigenomics-based diagnostics.

P. Laird, E. Diamandis, D. Sidransky, 2010, Clinical chemistry.

Reply to “Proteomic alterations of cancer-cell mitochondria: driver or bystander?”

D. Sidransky, M. Verma, S. Srivastava, 2003, Nature Reviews Cancer.

Microsatellite instability in bladder cancer.

D. Sidransky, K. Tokino, J. Ruppert, 1993, Cancer research.

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

A. Azmi, S. Prakash, P. Tran, 2015, Seminars in cancer biology.

Abstract 4097: Integrative analysis of epigenetic and transcriptional alterations in head and neck squamous cell carcinomas

Daria A. Gaykalova, J. Califano, D. Sidransky, 2012 .

Fluorescence Visualization Detection of Field Alterations in Tumor Margins of Oral Cancer Patients

Calum MacAulay, C. MacAulay, D. Sidransky, 2006, Clinical Cancer Research.

Prevention of Tumor Growth Driven by PIK3CA and HPV Oncogenes by Targeting mTOR Signaling with Metformin in Oral Squamous Carcinomas Expressing OCT3

V. Steele, A. Bode, I. Stijleman, 2015, Cancer Prevention Research.

Molecular markers in cancer: Can we make better predictions?

D. Sidransky, 1995, International journal of cancer.

Clinical Correlates of Promoter Hypermethylation of Four Target Genes in Head and Neck Cancer: A Cooperative Group Correlative Study

J. Manola, J. Roh, D. Sidransky, 2013, Clinical Cancer Research.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Gloria S. Huang, Rob J. Kulathinal, C. Smythe, 2015, Seminars in cancer biology.

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma

L. Cope, G. Netto, M. Hoque, 2013, Cell cycle.

Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma.

Identification of mtDNA mutations in human cancer.

David Sidransky, S. Nomoto, D. Sidransky, 2002, Methods in molecular biology.

Is human patched the gatekeeper of common skin cancers?

Michael Dean, Douglas E. Brash, Peter G. Zaphiropoulos, 1996, Nature Genetics.

Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence.

D. Sidransky, W. Westra, Jin Jen, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer

V. Velculescu, L. Marchionni, E. Fertig, 2014 .

Efficacy of weekly docetaxel and bevacizumab in mesenchymal chondrosarcoma: a new theranostic method combining xenografted biopsies with a mathematical model.

M. Wick, Z. Agur, D. Sidransky, 2008, Cancer research.

Role of protein kinase N2 (PKN2) in cigarette smoke-mediated oncogenic transformation of oral cells

Vishalakshi Nanjappa, H. Gowda, J. Califano, 2018, Journal of Cell Communication and Signaling.

Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress

D. Sidransky, E. Mambo, Aditi Chatterjee, 2006, BMC Cancer.

profiling uncovers , , and associated in from positive and negative patients treated with

L. Marchionni, J. White, D. Sidransky, 2017 .

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment

D. Sidransky, C. Michailidi, Rajagowthamee R. Thangavel, 2016, Oncotarget.

p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways.

R. Brosh, Y. Buganim, I. Goldstein, 2010, Cancer research.

Molecular and Cellular Pathobiology Cancer Research p 53 Regulates the Ras Circuit to Inhibit the Expression of a Cancer-Related Gene Signature by Various Molecular Pathways

V. Rotter, R. Brosh, Y. Buganim, 2010 .

Expression of GULP1 in bronchial epithelium is associated with the progression of emphysema in chronic obstructive pulmonary disease.

P. Illei, M. Hoque, D. Sidransky, 2017, Respiratory medicine.

Abstract 4512: Doublecortin-like kinase 1 (DCLK1) correlates with Notch pathway signaling, controls metastatic characteristics in head and neck cancer

A. Zhavoronkov, Jayshree Advani, Tejaswini Subbannayya, 2018, Molecular and Cellular Biology / Genetics.

Title: Mitochondrial DNA Mutation in Normal Margins and Tumors of Recurrent HNSCC Patients

J. Califano, D. Sidransky, W. Westra, 2010 .

Efficacy of weekly docetaxel and bevacizumab in mesenchymal chondrosarcoma: A new theranostic method combining xenografted biopsies with a mathematical model (Cancer Research (November 1, 2008) 68 (9033-9040))

M. Wick, Z. Agur, D. Sidransky, 2008 .

Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer

D. Sidransky, P. Cairns, Mark P. Schoenberg, 2000, International journal of cancer.

An accelerated pathway for targeted cancer therapies A well-defined pathway for the accelerated development and approval of targeted cancer therapies and companion diagnostics would reduce uncertainty, improve efficiency in development and provide an effective incentive for developers.

S. Friend, J. Benner, M. Mcclellan, 2011 .

Clusterin Is a Gene-Specific Target of microRNA-21 in Head and Neck Squamous Cell Carcinoma

Steven S. Chang, J. Califano, D. Sidransky, 2013, Clinical Cancer Research.