E. Setti

发表

Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.

J. R. Somoza, Dan Wang, J. Falgueyret, 2005, Journal of medicinal chemistry.

CURRENT APPROACHES TO OVERCOME BACTERIAL RESISTANCE

E. Setti, R. Micetich, L. Quattrocchio, 1997 .

3,4-disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P2 elements for selectivity.

D. Davis, E. Setti, J. McCarter, 2003, Bioorganic & medicinal chemistry letters.

3,4-Disubstituted Azetidinones as Selective Inhibitors of the Cysteine Protease Cathepsin K. Exploring P3 Elements for Potency and Selectivity.

D. Davis, E. Setti, J. McCarter, 2003 .

Synthesis and biological evaluation of penam sulfones as inhibitors of β-lactamases

E. Setti, R. Micetich, O. Phillips, 2005 .

Stereoselective synthesis of 6-fluoropenicillanate analogs of .beta.-lactamase inhibitors

E. Setti, E. G. Mata, O. Mascaretti, 1990 .

Highly chemoselective and stereocontrolled catalytic hydrogenolysis of the carbon-6-halogen bond of (pivaloyloxy)methyl 6,6-dihalo- and 6-halopenicillanates by 5% palladium on calcium carbonate and 5% rhodium on alumina

E. Setti, O. Mascaretti, D. U. Belinzoni, 1989 .

Highly chemoselective and stereocontrolled catalytic hydrogenolysis of the carbon-6-halogen bond of (pivaloyloxy)methyl 6,6-dihalopenicillanate by chlorotris(triphenylphosphine)rhodium(I) in homogeneous phase

E. Setti, O. Mascaretti, 1989 .

Synthesis of analogues of 6β-bromopenicillanic acid and penicillanic acid S,S-dioxide. Part 1. Synthesis of 3α-derivatives of 6β-bromo-2,2-dimethylpenam and 2,2-dimethylpenam S,S-dioxide

E. Setti, E. G. Mata, O. Mascaretti, 1988 .

Synthesis of (pivaloyloxy)methyl 6α-fluoropenicillanate

E. Setti, O. Mascaretti, 1988 .

Nucleophilic SN2 displacements on (pivaloyloxy)methyl 6.alpha.-[(fluorosulfonyl)oxy]penicillanate

E. Setti, O. Mascaretti, 1986 .

Synthesis of Analogues of 6β-Bromopenicillanic Acid and Penicillanic Acid S,S-Dioxide. Part 1. Synthesis of 3α-Derivatives of 6β-Bromo-2,2-dimethylpenam and 2,2-Dimethylpenam S,S-Dioxide.

E. Setti, E. G. Mata, O. Mascaretti, 1988 .

New trends in antimicrobial development.

E. Setti, R. Micetich, 2000, EXS.

Three possible hyperfragments

E. Setti, L. Scarsi, G. Tomasini, 1956 .

Identification of 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride (CEP-32496), a highly potent and orally efficacious inhibitor of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF) V600E.

A. Ghose, Brian T. Campbell, Raffaella Faraoni, 2012, Journal of medicinal chemistry.

4-Quinazolinyloxy-diaryl ureas as novel BRAFV600E inhibitors.

Brian T. Campbell, Raffaella Faraoni, Andiliy G. Lai, 2011, Bioorganic & Medicinal Chemistry Letters.

Chemical modification of tazobactam. Synthesis of 2 beta-[(4-substituted)-1,2,3-triazol-1-yl]methyl penicillanic acid sulfone derivatives.

E. Setti, R. Micetich, K. Atchison, 1995, Journal of antibiotics (Tokyo. 1968).

Chemical Modification of Tazobactam ‐ Synthesis of 2β‐((4‐ Substituted)‐1,2,3‐triazol‐1‐yl)methyl Penicillanic Acid Sulfone Derivatives.

E. Setti, R. Micetich, K. Atchison, 1996 .

Studies on penam sulfones III. Synthesis and β-lactamase inhibitory activity of sodium (6R)-6-(α-hydroxybenzyl)-2β-methoxyiminomethyl-2α-methylpenam-3α-carboxylate 1,1-dioxide and sodium 2β-acyl-2α-methylpenam-3α-carboxylate 1,1-dioxide

E. Setti, R. Micetich, O. Phillips, 1997 .

Studies on Penam Sulfones. Part 3. Synthesis and β‐Lactamase Inhibitory Activity of Sodium (6R)‐6‐(α‐Hydroxybenzyl)‐2β‐ methoxyiminomethyl‐2α‐methylpenam‐3α‐carboxylate 1,1‐ Dioxide and Sodium 2β‐Acyl‐2α‐methylpenam‐3α‐ carboxylate 1,1‐Dioxide.

E. Setti, R. Micetich, O. Phillips, 1997 .

Studies on penam sulfones. I. Synthesis and beta-lactamase inhibitory activity of 2 beta-alkoxycarbonyl penicillanic acid sulfones.

E. Setti, R. Micetich, K. Atchison, 1996, Journal of antibiotics (Tokyo. 1968).

Studies on monobactams II. Synthesis and β-lactamase inhibitory activity of 4α-methyl-3-[(thien-2-yl)-methylene]-2-azetidinone-1-sulfonate

E. Setti, R. Micetich, O. Phillips, 1998 .

Studies on Monobactams. Part 2. Synthesis and β-Lactamase Inhibitory Activity of 4α-Methyl-3-[(thien-2-yl)-methylene]-2-azetidinone-1-sulfonate.

E. Setti, R. Micetich, O. Phillips, 1999 .

Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K.

J. R. Somoza, C. Bayly, J. Palmer, 2006, Journal of Medicinal Chemistry.

Recent advances in the chemistry of beta-lactam compounds as selected active-site serine beta-lactamase inhibitors.

E. Setti, E. G. Mata, O. Mascaretti, 1999, Current pharmaceutical design.

3,4-disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P3 elements for potency and selectivity.

D. Jeffery, D. Davis, E. Setti, 2003, Bioorganic & medicinal chemistry letters.

A. Ghose, Brian T. Campbell, Raffaella Faraoni, 2012, Journal of medicinal chemistry.

Design and synthesis of tetracyclic nonpeptidic biaryl nitrile inhibitors of cathepsin K.

J. Palmer, E. Setti, S. Venkatraman, 2006, Bioorganic & medicinal chemistry letters.