P. Vayer

发表

ISIDA - Platform for Virtual Screening Based on Fragment and Pharmacophoric Descriptors

I. Tetko, D. Fourches, D. Horvath, 2008 .

New QSAR Models for Human Cytochromes P450, 1A2, 2D6 and 3A4 Implicated in the Metabolism of Drugs. Relevance of Dataset on Model Development.

P. Vayer, P. Bonnet, Sylvain Lozano, 2013, Molecular informatics.

New insights in the in vitro characterisation and molecular modelling of the P‐glycoprotein inhibitory promiscuity

O. Fardel, P. Vayer, G. Bocci, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A Computational Selection of Metabolite Biomarkers Using Emerging Pattern Mining: A Case Study in Human Hepatocellular Carcinoma.

P. Vayer, Sylvain Lozano, Alban Lepailleur, 2017, Journal of proteome research.

[Chemoinformatics and virtual screening of molecules for therapeutic use].

P. Vayer, B. Walther, A. Arrault, 2009, Medecine sciences : M/S.

QSAR Modelling of CYP3A4 Inhibition as a Screening Tool in the Context of DrugDrug Interaction Studies

Alban Arrault, Philippe Vayer, Dragos Horvath, 2012, Molecular informatics.

Tryptophan 5-hydroxylase. Rapid purification from whole rat brain and production of a specific antiserum.

P. Mandel, P. Vayer, M. Maitre, 1985, European journal of biochemistry.

Mining Chemical Libraries with "Screening Assistant 2"

Vincent Le Guilloux, Alban Arrault, Lionel Colliandre, 2012, J. Cheminformatics.

A specific gamma-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties.

P. Vayer, J. Bourguignon, M. Schmitt, 1990, The Journal of pharmacology and experimental therapeutics.

Gamma-hydroxybutyrate, a possible neurotransmitter.

P. Mandel, P. Vayer, M. Maitre, 1987, Life sciences.

Toward in silico structure-based ADMET prediction in drug discovery.

Philippe Vayer, Maria A Miteva, Bruno O Villoutreix, 2012, Drug discovery today.

Evidence for a role of high K m aldehyde reductase in the degradation of endogenous γ‐hydroxybutyrate from rat brain

P. Mandel, P. Vayer, J. Bourguignon, 1985, FEBS letters.

Gamma hydroxybutyrate distribution and turnover rates in discrete brain regions of the rat

P. Mandel, P. Vayer, M. Maitre, 1988, Neurochemistry International.

γ‐Hydroxybutyrate Stimulation of the Formation of Cyclic GMP and Inositol Phosphates in Rat Hippocampal Slices

P. Vayer, M. Maitre, 1989 .

UPLC–MS retention time prediction: a machine learning approach to metabolite identification in untargeted profiling

P. Vayer, Sylvain Lozano, A. Arrault, 2015, Metabolomics.

A rapid and sensitive method for the determination of gamma-hydroxybutyric acid and trans-gamma-hydroxycrotonic acid in rat brain tissue by gas chromatography/mass spectrometry with negative ion detection.

P. Vayer, M. Maitre, J. Ehrhardt, 1988, Biomedical & environmental mass spectrometry.

Pharmacophore‐based discovery of inhibitors of a novel drug/proton antiporter in human brain endothelial hCMEC/D3 cell line

P. Carrupt, L. Goracci, G. Cruciani, 2015, British journal of pharmacology.

Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA)

P. Svenningsson, M. Millan, A. Gobert, 2011, The Journal of Neuroscience.

Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain.

C. Wermuth, P. Mandel, P. Vayer, 1985, Biochemical pharmacology.

Regional differences in depolarization-induced release of γ-hydroxybutyrate from rat brain slices

P. Vayer, M. Maitre, 1988, Neuroscience Letters.

Effect of Anticonvulsant Drugs on 7‐Hydroxybutyrate Release from Hippocampal Slices: Inhibition by Valproate and Ethosuximide

P. Mandel, P. Vayer, M. Maitre, 1987, Journal of neurochemistry.

Conversion of γ‐Hydroxybutyrate to γ‐Aminobutyrate In Vitro

P. Mandel, P. Vayer, M. Maitre, 1985 .

UPLC–MS retention time prediction: a machine learning approach to metabolite identification in untargeted profiling

Alban Arrault, Philippe Vayer, Sylvain Lozano, 2015, Metabolomics.

In silico prediction of aqueous solubility: a multimodel protocol based on chemical similarity.

Florent Chevillard, Philippe Vayer, Maria A Miteva, 2012, Molecular pharmaceutics.

Function of gamma-hydroxybutyrate: a putative neurotransmitter.

P. Mandel, P. Vayer, M. Maitre, 1987, Biochemical Society transactions.

Mining collections of compounds with Screening Assistant 2

Vincent Le Guilloux, Alban Arrault, Lionel Colliandre, 2012, Journal of Cheminformatics.

Gamma-hydroxybutyrate stimulation of the formation of cyclic GMP and inositol phosphates in rat hippocampal slices.

P. Vayer, M. Maitre, 1989, Journal of neurochemistry.

Generative Topographic Mapping-Based Classification Models and Their Applicability Domain: Application to the Biopharmaceutics Drug Disposition Classification System (BDDCS)

Alban Arrault, Philippe Vayer, Dragos Horvath, 2013, J. Chem. Inf. Model..

Drug discovery and development: introduction to the general public and patient groups

P. Vayer, B. Villoutreix, J. Poyet, 2023, Frontiers in Drug Discovery.

ADME-Space: a new tool for medicinal chemists to explore ADME properties

G. Cruciani, P. Vayer, E. Carosati, 2017, Scientific Reports.

Interpretability of SAR/QSAR Models of any Complexity by Atomic Contributions

D Horvath, G Marcou, A Varnek, 2012, Molecular informatics.

ADME-Space: a new tool for medicinal chemists to explore ADME properties

Alban Arrault, Philippe Vayer, Gabriele Cruciani, 2017, Scientific Reports.

Comprehensive Network Map of ADME‐Tox Databases

Stéphane Bourg, Philippe Vayer, Baptiste Canault, 2017, Molecular informatics.

Is the anticonvulsant mechanism of valproate linked to its interaction with the cerebral gamma-hydroxybutyrate system?

P. Vayer, M. Maitre, C. Cash, 1988, Trends in pharmacological sciences.

Integrated structure- and ligand-based in silico approach to predict inhibition of cytochrome P450 2D6

Florent Chevillard, Philippe Vayer, Pablo Carbonell, 2015, Bioinform..