I. Jordens

发表

Rab7 and Rab27a control two motor protein activities involved in melanosomal transport.

I. Jordens, W. Westbroek, M. Marsman, 2006, Pigment cell research.

TMEM59 potentiates Wnt signaling by promoting signalosome formation

D. Egan, A. Heck, I. Jordens, 2018, Proceedings of the National Academy of Sciences.

Chaperoning antigen presentation by MHC class II molecules and their role in oncogenesis.

I. Jordens, M. Marsman, J. Neefjes, 2005, Advances in cancer research.

A splice variant of RILP induces lysosomal clustering independent of dynein recruitment.

I. Jordens, M. Marsman, Nuno Rocha, 2006, Biochemical and biophysical research communications.

Splice variant of the Rab 7 effector RILP induces lysosomal clustering without dynein motor recruitment

I. Jordens, M. Marsman, Nuno Rocha, 2006 .

Anti-LRP 5 / 6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells

I. Jordens, Michaela A. Gold, P. Gros, 2019 .

Insulin-regulated Aminopeptidase Is a Key Regulator of GLUT4 Trafficking by Controlling the Sorting of GLUT4 from Endosomes to Specialized Insulin-regulated Vesicles

I. Jordens, S. Keller, T. McGraw, 2010, Molecular biology of the cell.

GLUT4 Is Sorted to Vesicles Whose Accumulation Beneath and Insertion into the Plasma Membrane Are Differentially Regulated by Insulin and Selectively Affected by Insulin Resistance

I. Jordens, T. McGraw, Wenyong Xiong, 2010, Molecular biology of the cell.

Wnt Signaling Directs Neuronal Polarity and Axonal Growth

C. Hoogenraad, E. Stanganello, I. Jordens, 2019, iScience.

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling

Mitchell Ho, J. Carette, I. Jordens, 2020, eLife.

IL-24 The small GTPase Rab7 and its effector protein RILP regulate lysosomal transport

I. Jordens, M. Marsman, J. Neefjes, 2003 .

Rab 7 and Rab 27 a control two motor protein activities competing in melanosomal transport

I. Jordens, W. Westbroek, M. Marsman, 2006 .

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

H. Clevers, S. Mohammed, A. Heck, 2012, Nature.

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

Jacques Neefjes, Hans Janssen, I. Jordens, 2001, Current Biology.

Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments.

C. Echeverri, R. Vallee, I. Jordens, 1999, Journal of cell science.

Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150Glued, ORP1L, and the receptor βlll spectrin

W. Zwart, I. Jordens, Nuno Rocha, 2007, The Journal of cell biology.

Dynein-mediated vesicle transport controls intracellular Salmonella replication.

I. Jordens, M. Marsman, J. Neefjes, 2004, Molecular biology of the cell.

Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled

Britta A. M. Bouwman, I. Jordens, S. Rüdiger, 2012, Proceedings of the National Academy of Sciences.

Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho

Hailan Hu, Alan Hall, C. Goodman, 2001, Current Biology.

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

H. Clevers, I. Jordens, O. Basak, 2016, Nature.

RNF43 mutations facilitate mucinous colorectal cancer metastasis via formation of a tumour-intrinsic niche

I. Jordens, H. Snippert, S. Tejpar, 2022, bioRxiv.

Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex

Kris Gevaert, Joel Vandekerckhove, Alan Hall, 2001, Current Biology.

Variants in members of the cadherin–catenin complex, CDH1 and CTNND1, cause blepharocheilodontic syndrome

R. Hennekam, H. Kayserili, P. Lapunzina, 2018, European Journal of Human Genetics.

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells

I. Jordens, P. Gros, M. Maurice, 2019, Nature Communications.

RNF43 truncations trap CK1 to drive niche‐independent self‐renewal in cancer

R. Lindeboom, M. Vermeulen, I. Jordens, 2020, The EMBO journal.

RNF43 truncating mutations mediate a tumour suppressor-to-oncogene switch to drive niche-independent self-renewal in cancer

R. Lindeboom, M. Vermeulen, I. Jordens, 2019, bioRxiv.

Rab Proteins, Connecting Transport and Vesicle Fusion

I. Jordens, M. Marsman, J. Neefjes, 2005, Traffic.

RSPO3 Furin domain-conjugated liposomes for selective drug delivery to LGR5-high cells.

I. Jordens, M. Maurice, P. van Kerkhof, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network

A. Heck, I. Jordens, R. Boelens, 2016, Nature Structural &Molecular Biology.

RNF43 mutations facilitate colorectal cancer metastasis via formation of a tumour-intrinsic niche

I. Jordens, H. Snippert, S. Tejpar, 2023, bioRxiv.

Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2

I. Jordens, M. Maurice, B. Koo, 2023, bioRxiv.

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells

M. Goldflam, I. Jordens, P. Gros, 2019, Nature Communications.