Youyong Yuan

发表

One-Step Formulation of Targeted Aggregation-Induced Emission Dots for Image-Guided Photodynamic Therapy of Cholangiocarcinoma.

B. Tang, Min Li, Yang Gao, 2017, ACS nano.

A Photoactivatable AIE Polymer for Light-Controlled Gene Delivery: Concurrent Endo/Lysosomal Escape and DNA Unpacking.

Bin Liu, Youyong Yuan, Youyong Yuan, 2015, Angewandte Chemie.

Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells.

Ben Zhong Tang, Bin Liu, Meng Gao, 2015, Angewandte Chemie.

Theranostic Nanodots with Aggregation-Induced Emission Characteristic for Targeted and Image-Guided Photodynamic Therapy of Hepatocellular Carcinoma

Kenry, Yang Gao, Youyong Yuan, 2019, Theranostics.

Glutathione depletion and photosensitizer activation augments efficacy of tumor photodynamic immunotherapy

Youyong Yuan, Xiaofei Huang, Xiuhang Ruan, 2022, Chemical Engineering Journal.

AIEgens for Drug Delivery Applications

Youyong Yuan, B. Liu, Jing Liang, 2016 .

Targeted theranostic platinum(IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ.

Ben Zhong Tang, Bin Liu, Ryan T. K. Kwok, 2014, Journal of the American Chemical Society.

A FRET probe with AIEgen as the energy quencher: dual signal turn-on for self-validated caspase detection† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc00055j

Youyong Yuan, B. Liu, Ruoyu Zhang, 2016, Chemical science.

Bioorthogonal Equipping CAR-T Cells with Hyaluronidase and Checkpoint Blocking Antibody for Enhanced Solid Tumor Immunotherapy

Youyong Yuan, Shuhan Yang, Jun Li, 2022, ACS central science.

Tumor-responsive fluorescent light-up probe based on a gold nanoparticle/conjugated polyelectrolyte hybrid.

B. Liu, D. Ding, Kai Li, 2014, Small.

Tumor-Acidity and Bioorthogonal Chemistry-Mediated On-Site Size Transformation Clustered Nanosystem to Overcome Hypoxic Resistance and Enhance Chemoimmunotherapy.

Youyong Yuan, Q. Zong, Ye Liu, 2022, ACS nano.

A General Strategy for Macrotheranostic Prodrug Activation: Synergy by Tumor Acidic Microenvironment and Bioorthogonal Chemistry.

Youyong Yuan, Cong-Fei Xu, Yansong Dong, 2020, Angewandte Chemie.

A General Strategy for Macrotheranostic Prodrug Activation: Synergy between the Acidic Tumor Microenvironment and Bioorthogonal Chemistry

Youyong Yuan, Cong-Fei Xu, Yansong Dong, 2020 .

Biocompatible conjugated polymer nanoparticles for efficient photothermal tumor therapy.

N. Thakor, B. Liu, Youyong Yuan, 2015, Small.

Dual-Responsive Metabolic Precursor and Light-Up AIEgen for Cancer Cell Bio-orthogonal Labeling and Precise Ablation.

Youyong Yuan, B. Liu, Wenbo Wu, 2018, Analytical chemistry.

Cinnamaldehyde-based poly(thioacetal): A ROS-awakened self-amplifying degradable polymer for enhanced cancer immunotherapy.

Youyong Yuan, Ye Liu, Yansong Dong, 2022, Biomaterials.

Spatial specific delivery of combinational chemotherapeutics to combat intratumoral heterogeneity.

Youyong Yuan, N. Singh, Ye Liu, 2022, Journal of controlled release : official journal of the Controlled Release Society.

An NIR-Fluorophore-Based Theranostic for Selective Initiation of Tumor Pyroptosis-Induced Immunotherapy.

Youyong Yuan, Xuan Xiao, Kewei Wang, 2021, Small.

Self-Amplified Chain-Shattering Cinnamaldehyde-Based Poly(thioacetal) Boosts Cancer Chemo-Immunotherapy.

Xiaojiao Du, Youyong Yuan, Xuan Xiao, 2022, Acta biomaterialia.

Light-up probe based on AIEgens: dual signal turn-on for caspase cascade activation monitoring† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc04322d Click here for additional data file.

Ben Zhong Tang, Bin Liu, Youyong Yuan, 2017, Chemical science.

Dual drug delivery system with flexible and controllable drug ratios for synergistic chemotherapy

Youyong Yuan, Xuan Xiao, Rui Zheng, 2021, Science China Chemistry.

NIR photoregulated chemo- and photodynamic cancer therapy based on conjugated polyelectrolyte-drug conjugate encapsulated upconversion nanoparticles.

Bin Liu, Bengang Xing, Youyong Yuan, 2014, Nanoscale.

A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells† †Electronic supplementary information (ESI) available: Synthesis and characterization of the intermediates; molecular orbital data. See DOI: 10.1039/c5sc03583j

Youyong Yuan, B. Liu, Chong-Jing Zhang, 2015, Chemical science.

A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells

Youyong Yuan, B. Liu, Chong-Jing Zhang, 2015, Chemical science.

Conjugated polymer and drug co-encapsulated nanoparticles for chemo- and photo-thermal combination therapy with two-photon regulated fast drug release.

N. Thakor, M. Hong, B. Liu, 2015, Nanoscale.

Tuning the singlet-triplet energy gap: a unique approach to efficient photosensitizers with aggregation-induced emission (AIE) characteristics† †Electronic supplementary information (ESI) available: Synthesis and characterization of the intermediates and molecular orbital data. See DOI: 10.1039/c5sc

Deqing Zhang, Guanxin Zhang, Youyong Yuan, 2015, Chemical science.

Highly efficient photosensitizers with aggregation-induced emission characteristics obtained through precise molecular design.

Youyong Yuan, Wenbo Wu, P. Manghnani, 2017, Chemical communications.

A Highly Efficient and Photostable Photosensitizer with Near‐Infrared Aggregation‐Induced Emission for Image‐Guided Photodynamic Anticancer Therapy

Dan Ding, Wenbo Wu, Bin Liu, 2017, Advanced materials.

AIEgen based drug delivery systems for cancer therapy

Bin Liu, Yansong Dong, Youyong Yuan, 2018, Journal of controlled release : official journal of the Controlled Release Society.

A tumor microenvironment responsive nanoplatform with oxidative stress amplification for effective MRI-based visual tumor ferroptosis.

Youyong Yuan, Xinhua Wei, Ruimeng Yang, 2021, Acta biomaterialia.

Image-guided combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular probe with aggregation-induced emission characteristics† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc00826c Click here for additional data file.

Youyong Yuan, B. Liu, Xianmao Lu, 2015, Chemical science.

Size-Switchable Nanoparticles with Self-Destructive and Tumor Penetration Characteristics for Site-Specific Phototherapy of Cancer.

Youyong Yuan, Ruimeng Yang, Xinqing Jiang, 2020, ACS applied materials & interfaces.

Dual-Drug Backboned Polyprodrug with a Predefined Drug Combination for Synergistic Chemotherapy.

Youyong Yuan, Ruimeng Yang, Xinqing Jiang, 2021, Nano letters.

Conjugated-polyelectrolyte-based polyprodrug: targeted and image-guided photodynamic and chemotherapy with on-demand drug release upon irradiation with a single light source.

Bin Liu, Youyong Yuan, Youyong Yuan, 2014, Angewandte Chemie.

Visualization of drug delivery processes using AIEgens

Bin Liu, Youyong Yuan, Youyong Yuan, 2017, Chemical science.

Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation.

Youyong Yuan, Chong-Jing Zhang, Bin Liu, 2016, Journal of materials chemistry. B.

A platinum prodrug conjugated with a photosensitizer with aggregation-induced emission (AIE) characteristics for drug activation monitoring and combinatorial photodynamic-chemotherapy against cisplatin resistant cancer cells.

B. Liu, Youyong Yuan, Chong-Jing Zhang, 2015, Chemical communications.

Targeted theranostic prodrugs based on an aggregation-induced emission (AIE) luminogen for real-time dual-drug tracking.

Ben Zhong Tang, Bin Liu, Youyong Yuan, 2014, Chemical communications.

A targeted theranostic platinum(IV) prodrug containing a luminogen with aggregation-induced emission (AIE) characteristics for in situ monitoring of drug activation.

Ben Zhong Tang, Bin Liu, Youyong Yuan, 2014, Chemical communications.

Sequential Enzyme-Activated Macrotheranostic Probe for Selective Tumor Mitochondria Targeting.

Youyong Yuan, Xinhua Wei, Yuan Guo, 2021, Acta biomaterialia.

Intercellular delivery of bioorthogonal chemical receptors for enhanced tumor targeting and penetration.

Youyong Yuan, Jun Wang, Song Shen, 2020, Biomaterials.

Theranostic Heterodimeric Prodrug with Dual‐Channel Fluorescence Turn‐On and Dual‐Prodrug Activation for Synergistic Cancer Therapy

Youyong Yuan, Q. Zong, Xuan Xiao, 2021, Advanced healthcare materials.

Light‐Up Probe for Targeted and Activatable Photodynamic Therapy with Real‐Time In Situ Reporting of Sensitizer Activation and Therapeutic Responses

B. Tang, Youyong Yuan, Bin Liu, 2015 .

Polyprodrug with glutathione depletion and cascade drug activation for multi-drug resistance reversal.

Youyong Yuan, Q. Zong, Yansong Dong, 2021, Biomaterials.

Bioorthogonal Turn-On Probe Based on Aggregation-Induced Emission Characteristics for Cancer Cell Imaging and Ablation.

Bin Liu, Xiaolei Cai, Youyong Yuan, 2016, Angewandte Chemie.

Tumor-Acidity and Bioorthogonal Chemistry-Mediated Construction and Deconstruction of Drug Depots for Ferroptosis under Normoxia and Hypoxia.

Youyong Yuan, Kewei Wang, Mao-lin Jiang, 2022, Acta biomaterialia.

Tumor-Acidity and Bioorthogonal Chemistry Mediated Construction and Deconstruction of Drug Depots for Ferroptosis Under Normoxia and Hypoxia

Youyong Yuan, Kewei Wang, Mao-lin Jiang, 2022, Acta biomaterialia.

A fluorescent light-up nanoparticle probe with aggregation-induced emission characteristics and tumor-acidity responsiveness for targeted imaging and selective suppression of cancer cells

D. Ding, B. Tang, Youyong Yuan, 2015 .

Echinacea purpurea-derived homogeneous polysaccharide exerts anti-tumor efficacy via facilitating M1 macrophage polarization

Youyong Yuan, Zhaoqun Li, W. Ren, 2023, Innovation (Cambridge (Mass.)).

Bioorthogonal chemistry and illumination controlled programmed size-changeable nanomedicine for synergistic photodynamic and hypoxia-activated therapy.

Youyong Yuan, Ye Liu, Yansong Dong, 2022, Biomaterials.

Smart Probe for Tracing Cancer Therapy: Selective Cancer Cell Detection, Image-Guided Ablation, and Prediction of Therapeutic Response In Situ.

B. Liu, B. Tang, Youyong Yuan, 2015, Small.

Light-up bioprobe with aggregation-induced emission characteristics for real-time apoptosis imaging in target cancer cells.

Ben Zhong Tang, Dan Ding, Bin Liu, 2014, Journal of materials chemistry. B.

Self-assembled nanoparticles based on PEGylated conjugated polyelectrolyte and drug molecules for image-guided drug delivery and photodynamic therapy.

B. Liu, Youyong Yuan, 2014, ACS applied materials & interfaces.

Self-immolative polyprodrug-based tumor-specific cascade amplificated drug release nanosystem for orchestrated synergistic cancer therapy.

Youyong Yuan, Ye Liu, Xuan Xiao, 2022, Biomaterials.

Light-responsive AIE nanoparticles with cytosolic drug release to overcome drug resistance in cancer cells

Youyong Yuan, Chong-Jing Zhang, Shidang Xu, 2016 .

A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria.

Deqing Zhang, Guanxin Zhang, B. Liu, 2015, Chemical communications.

Rational design of fluorescent light-up probes based on an AIE luminogen for targeted intracellular thiol imaging.

Ben Zhong Tang, Bin Liu, Youyong Yuan, 2014, Chemical communications.

Time-programmed activation of dual polyprodrugs for synergistic cascade oxidation-chemotherapy.

Youyong Yuan, Ye Liu, Q. Zong, 2021, Biomaterials.

Fluorogen-peptide conjugates with tunable aggregation-induced emission characteristics for bioprobe design.

Ben Zhong Tang, Bin Liu, Jing Liang, 2014, ACS applied materials & interfaces.

ROS-Responsive Self-activatable Photosensitizing Agent for Photodynamic-Immunotherapy of cancer.

Youyong Yuan, Xinhua Wei, Ruimeng Yang, 2023, Acta biomaterialia.

Nitric oxide nano-prodrug platform with synchronous glutathione depletion and hypoxia relief for enhanced photodynamic cancer therapy.

Youyong Yuan, Xinhua Wei, Ruimeng Yang, 2021, Materials science & engineering. C, Materials for biological applications.

Smart activatable and traceable dual-prodrug for image-guided combination photodynamic and chemo-therapy.

Youyong Yuan, B. Liu, Wenbo Wu, 2017, Biomaterials.

Targeted and image-guided photodynamic cancer therapy based on organic nanoparticles with aggregation-induced emission characteristics.

Ben Zhong Tang, Bin Liu, Youyong Yuan, 2014, Chemical communications.

Cyclic amplification of intracellular ROS boosts enzymatic prodrug activation for enhanced chemo-immunotherapy.

Youyong Yuan, Ye Liu, Nianhua Wang, 2023, Acta biomaterialia.

Distinct optical and kinetic responses from E/Z isomers of caspase probes with aggregation-induced emission characteristics.

Ben Zhong Tang, Bin Liu, Meng Gao, 2014, Journal of materials chemistry. B.

A helical oncolytic polypeptide with potent membranolytic activity for cancer therapy.

J. Li, Youyong Yuan, Menghua Xiong, 2023, Biomaterials science.

Highly efficient photosensitizers with aggregation-induced emission characteristics obtained through precise molecular design.

Youyong Yuan, Wenbo Wu, P. Manghnani, 2017, Chemical communications.

Dual-locking nanoprobe based on hemicyanine for orthogonal stimuli-triggered precise cancer imaging and therapy.

Youyong Yuan, Q. Zong, Xuan Xiao, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Self-catalyzed tumor ferroptosis based on ferrocene conjugated reactive oxygen species generation and a responsive polymer.

Youyong Yuan, Q. Zong, Ye Liu, 2022, Chemical Communications.

Amplification of tumor oxidative stresses by Poly(disulfide acetal) for multidrug resistance reversal.

Youyong Yuan, Q. Zong, Jun Wang, 2021, Biomaterials.

A biosensor based on self-clickable AIEgen: a signal amplification strategy for ultrasensitive immunoassays.

Youyong Yuan, Wenbo Wu, Bin Liu, 2017, Chemical communications.

Targeted and image-guided photodynamic cancer therapy based on organic nanoparticles with aggregation-induced emission characteristics.

B. Tang, Youyong Yuan, B. Liu, 2014, Chemical communications.

Distinct optical and kinetic responses from E/Z isomers of caspase probes with aggregation-induced emission characteristics.

B. Tang, Youyong Yuan, B. Liu, 2014, Journal of materials chemistry. B.

Light-up bioprobe with aggregation-induced emission characteristics for real-time apoptosis imaging in target cancer cells.

D. Ding, B. Tang, Youyong Yuan, 2014, Journal of materials chemistry. B.

NIR photoregulated chemo- and photodynamic cancer therapy based on conjugated polyelectrolyte-drug conjugate encapsulated upconversion nanoparticles.

B. Liu, Youyong Yuan, Q. Hu, 2014, Nanoscale.

A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria.

Deqing Zhang, Guanxin Zhang, B. Liu, 2015, Chemical communications.

Conjugated-polyelectrolyte-based polyprodrug: targeted and image-guided photodynamic and chemotherapy with on-demand drug release upon irradiation with a single light source.

Youyong Yuan, B. Liu, Jie Liu, 2014, Angewandte Chemie.

A Highly Efficient and Photostable Photosensitizer with Near‐Infrared Aggregation‐Induced Emission for Image‐Guided Photodynamic Anticancer Therapy

D. Ding, Youyong Yuan, B. Liu, 2017, Advanced materials.

A dual-amplified ROS-responsive nanosystem with self-accelerating drug release for synergistic chemotherapy.

Youyong Yuan, Jun Li, Qingyu Zong, 2023, Chemical Communications.

Rational design of fluorescent light-up probes based on an AIE luminogen for targeted intracellular thiol imaging.

Youyong Yuan, Jing Liang, Guangxue Feng, 2014, Chemical communications.

Bioorthogonal Turn-On Probe Based on Aggregation-Induced Emission Characteristics for Cancer Cell Imaging and Ablation.

Youyong Yuan, B. Liu, Shidang Xu, 2016, Angewandte Chemie.