L. Leong

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NCCN Clinical Practice Guidelines in Oncology: colon cancer.

M. Choti, J. Fleshman, C. Willett, 2009, Journal of the National Comprehensive Cancer Network : JNCCN.

Metastatic colon cancer, version 3.2013: featured updates to the NCCN Guidelines.

M. Choti, C. Willett, Yi-Jen Chen, 2013, Journal of the National Comprehensive Cancer Network : JNCCN.

Phase II trial of carboplatin and infusional cyclosporine with alpha-interferon in recurrent ovarian cancer: a California Cancer Consortium Trial

Y. Yen, J. Doroshow, D. Gandara, 2006, International Journal of Gynecologic Cancer.

Rectal cancer clinical practice guidelines in oncology.

M. Choti, T. Yeatman, C. Willett, 2005, Journal of the National Comprehensive Cancer Network : JNCCN.

A Phase I Study of a Combination of Yttrium-90–Labeled Anti–Carcinoembryonic Antigen (CEA) Antibody and Gemcitabine in Patients with CEA-Producing Advanced Malignancies

L. Leong, J. Wong, L. Williams, 2009, Clinical Cancer Research.

Rectal Cancer

M. Choti, A. Benson, C. Willett, 2018, Springer International Publishing.

High-dose chemotherapy and stem-cell rescue in the treatment of high-risk breast cancer: prognostic indicators of progression-free and overall survival.

Y. Yen, J. Doroshow, L. Leong, 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Chemotherapy for metastatic colorectal cancer.

L. Leong, J. Rosales, 2005, Journal of the National Comprehensive Cancer Network : JNCCN.

A phase I study of oxaliplatin in combination with gemcitabine: correlation of clinical outcome with gene expression

Y. Yen, J. Doroshow, D. Gandara, 2007, Cancer Chemotherapy and Pharmacology.

Phase I/II Trial of Anticarcinoembryonic Antigen Radioimmunotherapy, Gemcitabine, and Hepatic Arterial Infusion of Fluorodeoxyuridine Postresection of Liver Metastasis for Colorectal Carcinoma.

L. Leong, J. Wong, A. Wu, 2017, Cancer biotherapy & radiopharmaceuticals.

Effective salvage therapy for refractory disseminated breast cancer with 5-fluorouracil and high-dose continuous infusion folinic acid.

J. Doroshow, L. Leong, S. Akman, 1988, Advances in experimental medicine and biology.

Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy.

J. Doroshow, L. Leong, S. Akman, 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I trial of 96-hour continuous infusion of dexrazoxane in patients with advanced malignancies.

S. Groshen, Y. Yen, J. Doroshow, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Long-term survival after high-dose chemotherapy followed by peripheral stem cell rescue for high-risk locally advanced/inflammatory and metastatic breast cancer.

J. Doroshow, W. Ye, L. Leong, 2011, Journal of Clinical Oncology.

Phase II study of 4 ′ -deoxydoxorubicin (esorubicin) in advanced or metastatic adenocarcinoma of the stomach

J. Doroshow, L. Leong, S. Akman, 1991, Investigational New Drugs.

p53-Reactive T Cells Are Associated with Clinical Benefit in Patients with Platinum-Resistant Epithelial Ovarian Cancer After Treatment with a p53 Vaccine and Gemcitabine Chemotherapy

L. Leong, S. Wilczynski, P. Frankel, 2018, Clinical Cancer Research.

Colon cancer, version 3.2014.

James D. Murphy, C. Willett, Yi-Jen Chen, 2014, Journal of the National Comprehensive Cancer Network : JNCCN.

Refractory metastatic breast cancer: salvage therapy with fluorouracil and high-dose continuous infusion leucovorin calcium.

J. Doroshow, L. Leong, S. Akman, 1989, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Long-term survival after high-dose chemotherapy followed by peripheral stem cell rescue for high-risk, locally advanced/inflammatory, and metastatic breast cancer.

J. Doroshow, W. Ye, L. Leong, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Phase II trial of combination intraperitoneal cisplatin and 5-fluorouracil in previously treated patients with advanced ovarian cancer: long-term follow-up.

J. Doroshow, L. Leong, G. Somlo, 2000, Gynecologic oncology.

Angiogenesis Inhibitors in the Treatment of Epithelial Ovarian Cancer

L. Leong, M. Wakabayashi, E. Han, 2013, Current Treatment Options in Oncology.

Enhancing Quality Improvements in Cancer Care Through CME Activities at a Nationally Recognized Cancer Center

L. Leong, R. Morgan, Marc Uemura, 2013, Journal of Cancer Education.

High-dose infusional doxorubicin and cyclophosphamide: a feasibility study of tandem high-dose chemotherapy cycles without stem cell support.

J. Doroshow, L. Leong, S. Akman, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Liver abscess as a complication of hepatic transarterial chemoembolization: a case report, literature review, and clinical recommendations.

L. Leong, A. Vanderwalde, H. Marx, 2009, Gastrointestinal cancer research : GCR.

Hepatic Artery Infusion (HAI) for Colorectal Liver Metastases and Complications of HAI Pump

L. Leong, M. Cho, 2017 .

Improved hepatic toxicity profile of portal vein adjuvant hepatic infusional chemotherapy.

L. Leong, L. Wagman, J. Longmate, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Tandem-cycle high-dose melphalan and cisplatin with peripheral blood progenitor cell support in patients with breast cancer and other malignancies.

Y. Yen, L. Leong, P. Frankel, 2001, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Phase I trial of carboplatin and infusional cyclosporin in advanced malignancy.

J. Doroshow, L. Leong, S. Akman, 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

High‐dose doxorubicin, etoposide, and cyclophosphamide with stem cell reinfusion in patients with metastatic or high‐risk primary breast cancer

J. Doroshow, L. Leong, S. Akman, 1994, Cancer.

Achieving physician well-being: the best physicians are well physicians.

L. Leong, 2014, Journal of the National Comprehensive Cancer Network : JNCCN.

Pharmacokinetics and toxicity of 120-hour continuous-infusion hydroxyurea in patients with advanced solid tumors

Y. Yen, J. Doroshow, L. Leong, 1996, Cancer Chemotherapy and Pharmacology.

Anal Carcinoma, Version 2.2012: featured updates to the NCCN guidelines.

M. Choti, J. Fleshman, C. Willett, 2012, Journal of the National Comprehensive Cancer Network : JNCCN.

A phase I trial of intraperitoneal nab-paclitaxel in the treatment of advanced malignancies primarily confined to the peritoneal cavity

L. Leong, B. Paz, P. Frankel, 2019, Cancer Chemotherapy and Pharmacology.

Phase I Trial of Intraperitoneal Gemcitabine in the Treatment of Advanced Malignancies Primarily Confined to the Peritoneal Cavity

Y. Yen, J. Doroshow, L. Leong, 2007, Clinical Cancer Research.

Phase Ib Trial of mFOLFOX6 and Everolimus (NSC-733504) in Patients with Metastatic Gastroesophageal Adenocarcinoma

M. Fakih, L. Leong, P. Frankel, 2016, Oncology.

Modulation of 5-fluorouracil with high-dose leucovorin calcium: activity in ovarian cancer and correlation with CA-125 levels.

J. Doroshow, L. Leong, S. Akman, 1995, Gynecologic oncology.

Anal carcinoma: Clinical practice guidelines in oncology™

M. Choti, J. Fleshman, J. Berlin, 2010 .

High‐dose cisplatin, etoposide, and cyclophosphamide with autologous stem cell reinfusion in patients with responsive metastatic or high‐risk primary breast cancer

J. Doroshow, L. Leong, S. Akman, 1994, Cancer.

Phase I study of mitomycin C and menadione in advanced solid tumors

J. Doroshow, L. Leong, S. Akman, 1995, Cancer Chemotherapy and Pharmacology.

Effect of low-dose prophylactic dopamine on high-dose cisplatin-induced electrolyte wasting, ototoxicity, and epidermal growth factor excretion: a randomized, placebo-controlled, double-blind trial.

J. Doroshow, L. Leong, G. Somlo, 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I trial of intraperitoneal docetaxel in the treatment of advanced malignancies primarily confined to the peritoneal cavity: dose-limiting toxicity and pharmacokinetics.

Y. Yen, J. Doroshow, L. Leong, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Treatment of metastatic malignant melanoma with trimetrexate: a phase II study.

J. Doroshow, L. Leong, S. Akman, 1990, Medical and pediatric oncology.

Cisplatin and infusional cytosine arabinoside for the treatment of colorectal adenocarcinoma: a phase II trial.

J. Doroshow, L. Leong, S. Akman, 1999, Cancer investigation.

Mitomycin C and menadione for the treatment of advanced gastrointestinal cancers: a phase II trial

J. Doroshow, L. Leong, S. Akman, 1995, Journal of Cancer Research and Clinical Oncology.

Mitomycin C and menadione for the treatment of lung cancer: a phase II trial

J. Doroshow, L. Leong, S. Akman, 2004, Investigational New Drugs.

A study of radiotherapy modalities combined with continuous 5-FU infusion for locally advanced gastrointestinal malignancies.

Y. Yen, J. Doroshow, L. Leong, 2004, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

A phase I trial of (90)Y-DOTA-anti-CEA chimeric T84.66 (cT84.66) radioimmunotherapy in patients with metastatic CEA-producing malignancies.

L. Leong, J. Wong, A. Wu, 2006, Cancer biotherapy & radiopharmaceuticals.

Phase I trial of intraperitoneal iododeoxyuridine with and without intravenous high-dose folinic acid in the treatment of advanced malignancies primarily confined to the peritoneal cavity: flow cytometric and pharmacokinetic analysis.

Y. Yen, J. Doroshow, L. Leong, 1998, Cancer research.

Tandem high-dose chemotherapy followed by autologous transplantation in patients with locally advanced or metastatic sarcoma.

L. Leong, P. Frankel, G. Somlo, 2009, Anticancer research.

High-dose paclitaxel in combination with doxorubicin, cyclophosphamide and peripheral blood progenitor cell rescue in patients with high-risk primary and responding metastatic breast carcinoma: toxicity profile, relationship to paclitaxel pharmacokinetics and short-term outcome

Y. Yen, J. Doroshow, L. Leong, 2001, British Journal of Cancer.

High-dose continuous infusion folinic acid and bolus 5-fluorouracil in patients with advanced colorectal cancer: a phase II study.

J. Doroshow, L. Leong, B. Carr, 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I pharmacodynamic study of time and sequence dependency of hydroxyurea in combination with gemcitabine: a California Cancer Consortium Trial

Y. Yen, J. Doroshow, D. Gandara, 2002, Cancer Chemotherapy and Pharmacology.

Phase II trial of intraperitoneal cisplatin with intravenous doxorubicin and cyclophosphamide in previously untreated patients with advanced ovarian cancer-long-term follow-up.

J. Doroshow, L. Leong, G. Somlo, 1999, Gynecologic oncology.

Treatment of germ cell cancer with two cycles of high-dose ifosfamide, carboplatin, and etoposide with autologous stem-cell support.

J. Doroshow, L. Leong, G. Somlo, 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

5-Fluorouracil and high-dose calcium leucovorin for hepatocellular carcinoma: a phase II trial.

J. Doroshow, L. Leong, S. Akman, 1995, Cancer investigation.

Paclitaxel-based high-dose chemotherapy with autologous stem cell rescue for relapsed germ cell cancer.

Y. Yen, J. Doroshow, L. Leong, 2005, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Pharmacokinetics and toxicity of high-dose intravenous methotrexate in the treatment of leptomeningeal carcinomatosis

J. Doroshow, L. Leong, S. Akman, 2000, Cancer Chemotherapy and Pharmacology.

Phase II trial of cisplatin and alpha-interferon in advanced malignant melanoma.

J. Doroshow, L. Leong, S. Akman, 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase II trial of bryostatin-1 in combination with cisplatin in patients with recurrent or persistent epithelial ovarian cancer: a California cancer consortium study

J. Doroshow, D. Gandara, H. Lenz, 2012, Investigational New Drugs.

Colon cancer clinical practice guidelines in oncology.

M. Choti, T. Yeatman, Yi-Jen Chen, 2005, Journal of the National Comprehensive Cancer Network : JNCCN.

Phase I study of cisdiamminedichloroplatinum in combination with azidothymidine in the treatment of patients with advanced malignancies

J. Niland, Y. Yen, J. Doroshow, 2003, Cancer Chemotherapy and Pharmacology.

Phase II trial of 5-fluorouracil, high-dose leucovorin calcium, and dipyridamole in advanced prostate cancer

J. Doroshow, L. Leong, S. Akman, 2005, Journal of Cancer Research and Clinical Oncology.

Effective initial therapy of advanced breast cancer with fluorouracil and high-dose, continuous infusion calcium leucovorin.

J. Doroshow, L. Leong, S. Akman, 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Pharmacokinetics and toxicity of continuous infusion (6S)-folinic acid and bolus 5-fluorouracil in patients with advanced cancer.

J. Doroshow, L. Leong, S. Akman, 1992, Cancer research.

3-Deazaguanine: Report of a phase I trial and drug-related cardiac toxicity

J. Doroshow, L. Leong, S. Akman, 1990, Investigational New Drugs.

Fetal hemoglobin gene activation in a phase II study of 5,6-dihydro-5-azacytidine for bronchogenic carcinoma.

J. Doroshow, L. Leong, B. Carr, 1987, Cancer research.

Clinical Practice Guidelines in Oncology TM

M. Choti, J. Fleshman, C. Willett, 2009 .

Localized Colon Cancer, version 3.2013

M. Choti, C. Willett, C. Fuchs, 2013 .

Localized colon cancer, version 3.2013: featured updates to the NCCN Guidelines.

M. Choti, C. Willett, Yi-Jen Chen, 2013, Journal of the National Comprehensive Cancer Network : JNCCN.

Phase I trial of GTI-2040, oxaliplatin, and capecitabine in the treatment of advanced metastatic solid tumors: a California Cancer Consortium Study

Y. Yen, J. Doroshow, D. Gandara, 2009, Cancer Chemotherapy and Pharmacology.

Rectal cancer.

M. Choti, Yi-Jen Chen, C. Fuchs, 2012, Journal of the National Comprehensive Cancer Network : JNCCN.

NCCN Clinical Practice Guidelines in Oncology: rectal cancer.

Christopher Willett, Michael A Choti, Krystyna Kiel, 2009, Journal of the National Comprehensive Cancer Network : JNCCN.

NCCN clinical practice guidelines in oncology. Anal carcinoma.

M. Choti, J. Fleshman, J. Berlin, 2010, Journal of the National Comprehensive Cancer Network : JNCCN.

A Phase II Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) in Metastatic Breast Cancer: A California Cancer Consortium Study

David D. Smith, James H. Doroshow, Paul Frankel, 2008, Clinical Cancer Research.

Phase II trial of carboplatin and infusional cyclosporine in platinum-resistant recurrent ovarian cancer

Y. Yen, J. Doroshow, D. Gandara, 2004, Cancer Chemotherapy and Pharmacology.

A phase I/II prospective, single arm trial of gefitinib, trastuzumab, and docetaxel in patients with stage IV HER-2 positive metastatic breast cancer

S. Kane, L. Leong, C. Russell, 2012, Breast Cancer Research and Treatment.

Effect of CD34 " Selection and Various Schedules of Stem Cell Reinfusion and Granulocyte Colony-Stimulating Factor Priming on Hematopoietic Recovery After High-Dose Chemotherapy for Breast Cancer

J. Doroshow, L. Leong, T. Odom-Maryon, 1997 .

Effect of CD34+ selection and various schedules of stem cell reinfusion and granulocyte colony-stimulating factor priming on hematopoietic recovery after high-dose chemotherapy for breast cancer.

J. Doroshow, L. Leong, T. Odom-Maryon, 1997, Blood.

Phase II Study of Oxaliplatin in Patients With Unresectable, Metastatic, or Recurrent Hepatocellular Cancer: A California Cancer Consortium Trial

Y. Yen, D. Gandara, H. Lenz, 2008, American journal of clinical oncology.

Phase I trial of continuous infusion 5-aza-2′-deoxycytidine

P. Laird, L. Leong, S. Baker, 2003, Cancer Chemotherapy and Pharmacology.

p53MVA Therapy in Patients with Refractory Gastrointestinal Malignancies Elevates p53-Specific CD8+ T-cell Responses

Y. Yen, M. Fakih, L. Leong, 2014, Clinical Cancer Research.

Quality Improvement Education for Venous Thromboembolism (VTE) Prevention in Cancer

L. Leong, R. Morgan, M. Mendelsohn, 2015, The Journal of continuing education in the health professions.

Randomized trial of oral cyclophosphamide versus oral cyclophosphamide with celecoxib for recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer.

Y. Yen, L. Leong, P. Frankel, 2019, Cancer treatment and research communications.

Feasibility and pharmacokinetic study of infusional dexrazoxane and dose-intensive doxorubicin administered concurrently over 96 h for the treatment of advanced malignancies

Y. Yen, J. Doroshow, L. Leong, 2004, Cancer Chemotherapy and Pharmacology.

Phase I trial of menadiol diphosphate (vitamin K3) in advanced malignancy

J. Doroshow, L. Leong, S. Akman, 2005, Investigational New Drugs.

Plasma and cerebrospinal fluid pharmacokinetics of topotecan in a phase I trial of topotecan, tamoxifen, and carboplatin, in the treatment of recurrent or refractory brain or spinal cord tumors

Yun Yen, James H. Doroshow, Adam Mamelak, 2010, Cancer Chemotherapy and Pharmacology.

Recombinant human thrombopoietin in combination with granulocyte colony-stimulating factor enhances mobilization of peripheral blood progenitor cells, increases peripheral blood platelet concentration, and accelerates hematopoietic recovery following high-dose chemotherapy.

S. Vuk-Pavlović, Y. Yen, J. Doroshow, 1999, Blood.

Quality-of-Life Issues in the Management of Epithelial Ovarian Cancer

L. Leong, B. Ferrell, T. Lowe, 2007, Current treatment options in oncology.

Predictors of long-term outcome following high-dose chemotherapy in high-risk primary breast cancer

J. Doroshow, L. Leong, P. Frankel, 2002, British Journal of Cancer.

Phase II trial of high-dose intravenous doxorubicin, etoposide, and cyclophosphamide with autologous stem cell support in patients with residual or responding recurrent ovarian cancer

Y. Yen, L. Leong, G. Somlo, 2001, Bone Marrow Transplantation.

Oligometastatic Breast Cancer Patients Treated with High-Dose Chemotherapy and Targeted Radiation: Long-Term Follow-Up of a Phase II Trial

A. Amini, L. Leong, P. Frankel, 2022, Cancers.

Genomic Analyses of Germline and Somatic Variation in High-Grade Serous Ovarian Cancer

S. Neuhausen, L. Leong, S. Wilczynski, 2023, Journal of Ovarian Research.

Vorinostat (suberoylanilide hydroxamic acid) as salvage therapy in metastatic breast cancer (MBC): A California Cancer Consortium phase II study

D. Gandara, L. Leong, P. Frankel, 2007 .

A phase I study of carboplatin and etoposide administered in conjunction with dipyridamole, prochlorperazine and cyclosporine A

Y. Yen, J. Doroshow, L. Leong, 2000, Cancer Chemotherapy and Pharmacology.

Pilot study of an interdisciplinary supportive care planning intervention in pancreatic cancer

M. Fakih, L. Leong, B. Ferrell, 2016, Supportive Care in Cancer.

Pharmacologic advantage (PA) of intraperitoneal (IP) nab-paclitaxel in patients with advanced malignancies primarily confined to the peritoneal cavity.

L. Leong, P. Frankel, I. Paz, 2015 .

Colon Cancer , Version 3 . 2014 Clinical Practice Guidelines in Oncology

A. Benson, James D. Murphy, C. Willett, 2014 .

Fluorouracil and leucovorin in advanced breast cancer.

J. Doroshow, L. Leong, S. Akman, 1993, Advances in experimental medicine and biology.

Phase II trial of 5-fluorouracil and high-dose folinic acid as first- or second-line therapy for advanced breast cancer.

S. Green, J. Doroshow, L. Leong, 1994, American journal of clinical oncology.

A phase I study of bortezomib and temozolomide in patients with advanced solid tumors

L. Leong, P. Frankel, M. Cristea, 2012, Cancer Chemotherapy and Pharmacology.

Rectal cancer, version 2.2015: Featured updates to the NCCN guidelines

James D. Murphy, C. Willett, C. Fuchs, 2015 .

Prognostic indicators and survival in patients with stage IIIB inflammatory breast carcinoma after dose-intense chemotherapy.

Y. Yen, J. Doroshow, L. Leong, 2004, Journal of Clinical Oncology.

Phase I study of 5-day continuous infusion fluorodeoxyuridine and high-dose folinic acid with oral hydroxyurea

J. Doroshow, L. Leong, S. Akman, 2004, Cancer Chemotherapy and Pharmacology.

Synchronous metastatic rectal cancer completely resected after multidisciplinary planning and treatment: a case report.

L. Leong, H. Schoellhammer, Gagandeep Singh, 2013, Journal of the National Comprehensive Cancer Network : JNCCN.

Rectal Cancer, Version 2.2015.

James D. Murphy, C. Willett, Yi-Jen Chen, 2015, Journal of the National Comprehensive Cancer Network : JNCCN.

City of hope cancer center hematology–oncology fellowship and hematopoietic stem cell transplantation fellowship

A. Krishnan, L. Leong, K. Reckamp, 2011, American journal of hematology.

Phase II study of oxaliplatin in patients with unresectable, metastatic or recurrent hepatocellular cancer.

L. Leong, L. Wagman, S. Shibata, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A phase II trial of bryostatin in combination with cisplatin in patients with recurrent or persistent epithelial ovarian cancer: A California cancer consortium (CCC) trial

J. Doroshow, D. Gandara, L. Leong, 2005 .