A. Orry

发表

Ligand docking and structure-based virtual screening in drug discovery.

Claudio N. Cavasotto, C. Cavasotto, A. Orry, 2007, Current topics in medicinal chemistry.

Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.

Claudio N. Cavasotto, R. Abagyan, F. Monsma, 2008, Journal of medicinal chemistry.

Modeling and docking the endothelin G-protein-coupled receptor.

B. Wallace, A. Orry, B A Wallace, 2000, Biophysical journal.

Molecular Basis of Secretin Docking to Its Intact Receptor Using Multiple Photolabile Probes Distributed throughout the Pharmacophore*

Ruben Abagyan, Laurence J Miller, Patrick M Sexton, 2011, The Journal of Biological Chemistry.

Efficient synthetic inhibitors of anthrax lethal factor.

Dawoon Jung, Maurizio Pellecchia, Alex Y Strongin, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Homology Modeling

R. Abagyan, A. Orry, Ruben Abagyan, 2020, Methods in Molecular Biology.

Synergistic interactions of repurposed drugs that inhibit Nsp1, a major virulence factor for COVID-19

H. Kao, A. Orry, M. Palfreyman, 2022, Scientific Reports.

Riproximin Exhibits Diversity in Sugar Binding, and Modulates some Metastasis-Related Proteins with Lectin like Properties in Pancreatic Ductal Adenocarcinoma

A. Orry, M. Berger, K. Klika, 2020, Frontiers in Pharmacology.

Structural Evidence for a Role of the Multi-functional Human Glycoprotein Afamin in Wnt Transport.

M. Keller, B. Rupp, D. Nurizzo, 2017, Structure.

Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor

R. Abagyan, P. Sexton, A. Christopoulos, 2019, Molecular Pharmacology.

Isolation and characterisation of microsatellites from hexaploid bread wheat

G. Bryan, A. Orry, J. B. Smith, 1997, Theoretical and Applied Genetics.

Characterization of the Thermotoga maritima ADP‐glucose pyrophosphorylase: Both glgC and glgD Subunits are Required for Optimal Activity and Allosteric regulation

A. Orry, C. Meyer, Sean V. Nisperos, 2010 .

Analyses of circular dichroism spectra of membrane proteins

Jonathan G. Lees, R. W. Janes, J. Lees, 2003, Protein science : a publication of the Protein Society.

Enzymatic Route toward 6‐Methylated Baeocystin and Psilocybin

B. Rupp, A. Orry, D. Hoffmeister, 2019, Chembiochem : a European journal of chemical biology.

Genetic Relatedness of Infectious Hypodermal and Hematopoietic Necrosis Virus Isolates, United States, 2019

A. Orry, M. Killian, J. Ramos, 2022, Emerging infectious diseases.

infectious pancreatic necrosis virus

A. Orry, F. Allnutt, S. Lapatra, 2022, CABI Compendium.

Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity across the Receptor Homodimeric Complex.

R. Abagyan, P. Sexton, A. Christopoulos, 2015, Journal of medicinal chemistry.

Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor.

Ruben Abagyan, Ling Wang, Ronen Marmorstein, 2010, Chemistry & biology.

Differential Loss of Prolyl Isomerase or Chaperone Activity of Ran-binding Protein 2 (Ranbp2) Unveils Distinct Physiological Roles of Its Cyclophilin Domain in Proteostasis*

A. Orry, N. Peachey, H. Yi, 2014, The Journal of Biological Chemistry.

Development of a Highly Selective Allosteric Antagonist Radioligand for the Type 1 Cholecystokinin Receptor and Elucidation of Its Molecular Basis of Binding

R. Abagyan, P. Sexton, A. Christopoulos, 2015, Molecular Pharmacology.

Targeting the cyclophilin domain of Ran-binding protein 2 (Ranbp2) with novel small molecules to control the proteostasis of STAT3, hnRNPA2B1 and M-opsin.

A. Orry, S. E. Park, P. Ferreira, 2015, ACS chemical neuroscience.

From Drosophila to Humans: Reflections on the Roles of the Prolyl Isomerases and Chaperones, Cyclophilins, in Cell Function and Disease

A. Orry, P. Ferreira, 2012, Journal of neurogenetics.

Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms

A. Orry, H. Yi, P. Ferreira, 2011, Biology Open.

Structural and functional plasticity of subcellular tethering , targeting and processing of RPGRIP 1 by RPGR isoforms

A. Orry, H. Yi, P. Ferreira, 2011 .

Mapping spatial approximations between the amino terminus of secretin and each of the extracellular loops of its receptor using cysteine trapping

Ruben Abagyan, Laurence J Miller, Patrick M Sexton, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structure-based development of target-specific compound libraries.

Claudio N Cavasotto, Andrew J W Orry, Ruben A Abagyan, 2006, Drug discovery today.

Purification, kinetic characterization, and site-directed mutagenesis of Methanothermobacter thermautotrophicus RFAP Synthase Produced in Escherichia coli

A. Orry, M. Rasche, M. Bechard, 2019, AIMS microbiology.

Molecular Basis for Benzodiazepine Agonist Action at the Type 1 Cholecystokinin Receptor*

R. Abagyan, P. Sexton, A. Christopoulos, 2013, The Journal of Biological Chemistry.

Molecular Basis for Binding and Subtype Selectivity of 1,4-Benzodiazepine Antagonist Ligands of the Cholecystokinin Receptor*

R. Abagyan, P. Sexton, P. Lam, 2012, The Journal of Biological Chemistry.

Structure based design and synthesis of novel Toll-like Receptor 2 (TLR 2) lipid antagonists.

R. Abagyan, A. Orry, W. Wrasidlo, 2021, Bioorganic & medicinal chemistry letters.

Homology Modeling: Methods and Protocols

Ruben Abagyan, Andrew Orry, R. Abagyan, 2023, Methods in Molecular Biology.

The Challenge of Considering Receptor Flexibility in Ligand Docking and Virtual Screening

Claudio N. Cavasotto, Ruben Abagyan, Andrew Orry, 2005 .

Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor*

R. Abagyan, P. Sexton, A. Christopoulos, 2016, The Journal of Biological Chemistry.

Secretin Occupies a Single Protomer of the Homodimeric Secretin Receptor Complex

R. Abagyan, P. Sexton, P. Lam, 2010, The Journal of Biological Chemistry.

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2

A. Orry, James Lee, P. Ferreira, 2013, Open Biology.

Preparation and refinement of model protein-ligand complexes.

R. Abagyan, A. Orry, 2012, Methods in molecular biology.

Structure‐based identification of binding sites, native ligands and potential inhibitors for G‐protein coupled receptors

Claudio N. Cavasotto, Claudio N Cavasotto, Andrew J W Orry, 2003, Proteins.