B. Brenner

发表

A force transducer for measuring mechanical properties of single cardiac myocytes.

C. Tasche, E. Meyhöfer, B. Brenner, 1999, American journal of physiology. Heart and circulatory physiology.

A new detection system for extremely small vertically mounted cantilevers

A Ulcinas, S. Simpson, P. Heard, 2008, Nanotechnology.

Variability in the ratio of mutant to wildtype myosin heavy chain present in the soleus muscle of patients with familial hypertrophic cardiomyopathy. A new approach for the quantification of mutant to wildtype protein

M. Raida, B. Brenner, W. Forssmann, 1999, FEBS letters.

Transformation of the Nonprocessive Fast Skeletal Myosin II into a Processive Motor.

B. Brenner, W. Steffen, G. Tsiavaliaris, 2019, Small.

Equilibration and exchange of fluorescently labeled molecules in skinned skeletal muscle fibers visualized by confocal microscopy.

B. Brenner, B. Rothen‐Rutishauser, T. Wallimann, 1995, Biophysical journal.

Response to the Letter by Geeves and Lehrer

B. Brenner, Yi-der Chen, B. Yan, 2002 .

Theoretical kinetic studies of models for binding myosin subfragment-1 to regulated actin: Hill model versus Geeves model.

B. Brenner, B. Yan, J. Chalovich, 2001, Biophysical journal.

Targeted optimization of a protein nanomachine for operation in biohybrid devices.

B. Brenner, D. Manstein, C. Urbanke, 2010, Angewandte Chemie.

Lipoteichoic acid from Staphylococcus aureus directly affects cardiomyocyte contractility and calcium transients.

P. Vogt, B. Brenner, A. Niederbichler, 2013, Molecular immunology.

Force enhancement without changes in cross-bridge turnover kinetics: the effect of EMD 57033.

B. Brenner, T. Kraft, 1997, Biophysical journal.

Structures of actomyosin crossbridges in relaxed and rigor muscle fibers.

B. Brenner, L. Yu, 1989, Biophysical journal.

Cycling Cross-Bridges Contribute to Thin Filament Activation in Human Slow-Twitch Fibers

B. Brenner, Anna Á. Rauscher, A. Málnási-Csizmadia, 2020, Frontiers in Physiology.

Quantification of mutant versus wild-type myosin in human muscle biopsies using nano-LC/ESI-MS.

B. Brenner, A. Francino, F. Navarro‐López, 2007, Analytical chemistry.

Hypertrophic cardiomyopathy-related beta-myosin mutations cause highly variable calcium sensitivity with functional imbalances among individual muscle cells.

M. Antognozzi, B. Brenner, H. Kubis, 2005, American journal of physiology. Heart and circulatory physiology.

Familial hypertrophic cardiomyopathy: functional effects of myosin mutation R723G in cardiomyocytes.

B. Brenner, A. Brandis, J. van der Velden, 2013, Journal of molecular and cellular cardiology.

The Delta 14 mutation of human cardiac troponin T enhances ATPase activity and alters the cooperative binding of S1-ADP to regulated actin.

P. Chase, B. Brenner, J. Chalovich, 2004, Biochemistry.

Mg2+‐free ATP regulates the processivity of native cytoplasmic dynein

B. Brenner, M. Geeves, W. Steffen, 2019, FEBS letters.

Actin sliding on reconstituted myosin filaments containing only one myosin heavy chain isoform

B. Brenner, T. Scholz, 2004, Journal of Muscle Research & Cell Motility.

Inhibition of cross-bridge binding to actin by caldesmon fragments in skinned skeletal muscle fibers.

B. Brenner, R. Hartwell, J. Chalovich, 1997, Biophysical journal.

The mechanism of pentabromopseudilin inhibition of myosin motor activity

B. Brenner, D. Manstein, H. Gutzeit, 2009, Nature Structural &Molecular Biology.

Parallel inhibition of active force and relaxed fiber stiffness in skeletal muscle by caldesmon: implications for the pathway to force generation.

B. Brenner, J. Chalovich, L. Yu, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Effect of free sarcoplasmic Ca2+ concentration on maximum unloaded shortening velocity: measurements on single glycerinated rabbit psoas muscle fibres

B. Brenner, 1980, Journal of Muscle Research & Cell Motility.

Involvement of weak binding crossbridges in force production in muscle

B. Brenner, Leepo C. Yu, J. Chalovich, 1991, Journal of Muscle Research & Cell Motility.

Sarcomeric binding pattern of exogenously added intact caldesmon and its C-terminal 20-kDa fragment in skinned fibers of skeletal muscle

M. Reedy, B. Brenner, J. Chalovich, 1999, Journal of Muscle Research & Cell Motility.

Radial equilibrium lengths of actomyosin cross-bridges in muscle.

B. Brenner, J. Chalovich, L. Yu, 1996, Biophysical journal.

Caldesmon Derived Polypeptides as Probes of Force Production in Skeletal Muscle

B. Brenner, Leepo C. Yu, J. Chalovich, 1991 .

Rate of force generation in muscle: correlation with actomyosin ATPase activity in solution.

E. Eisenberg, B. Brenner, B Brenner, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Unequal allelic expression of wild-type and mutated β-myosin in familial hypertrophic cardiomyopathy

B. Brenner, W. McKenna, K. Osterziel, 2011, Basic Research in Cardiology.

Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms

B. Brenner, C. D. dos Remedios, B. Iorga, 2018, Front. Physiol..

Muscle Mechanics and Biochemical Kinetics

B. Brenner, 1990 .

Effect of Ca2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction.

B. Brenner, B Brenner, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Evidence for cross-bridge attachment in relaxed muscle at low ionic strength.

E. Eisenberg, B. Brenner, L. Greene, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Kinetics of thin filament activation probed by fluorescence of N-((2-(iodoacetoxy)ethyl)-N-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole-labeled troponin I incorporated into skinned fibers of rabbit psoas muscle: implications for regulation of muscle contraction.

B. Brenner, J. Chalovich, 1999, Biophysical journal.

sliding , G203S, K206Q) enhance filament Δ troponin I (K183 Familial hypertrophic cardiomyopathy mutations in

A. M. Gordon, D. Martyn, M. Regnier, 2015 .

Familial hypertrophic cardiomyopathy mutations in troponin I (K183D, G203S, K206Q) enhance filament sliding.

A. M. Gordon, D. Martyn, M. Regnier, 2003, Physiological genomics.

Parallel inhibition of active force and relaxed fiber stiffness by caldesmon fragments at physiological ionic strength and temperature conditions: additional evidence that weak cross-bridge binding to actin is an essential intermediate for force generation.

B. Brenner, J. Chalovich, T. Kraft, 1995, Biophysical journal.

X-ray diffraction evidence for cross-bridge formation in relaxed muscle fibers at various ionic strengths.

B. Brenner, R. J. Podolsky, L. Yu, 1984, Biophysical journal.

Cross-bridge attachment in relaxed muscle.

E. Eisenberg, B. Brenner, L. Greene, 1984, Advances in experimental medicine and biology.

Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes

B. Brenner, T. Thum, B. Iorga, 2016, Basic Research in Cardiology.

Technique for stabilizing the striation pattern in maximally calcium-activated skinned rabbit psoas fibers.

B. Brenner, 1983, Biophysical journal.

Single-molecule tracking of myosins with genetically engineered amplifier domains

Dietmar J. Manstein, Christine Ruff, E. Meyhöfer, 2001, Nature Structural Biology.

X-ray diffraction studies of the cross-bridge intermediate states.

B. Brenner, G. Rapp, J. Chalovich, 1998, Advances in experimental medicine and biology.

Hypertrophic cardiomyopathy MYH7-mutation R723G alters mRNA secondary structure.

B. Brenner, T. Kraft, J. Rose, 2019, Physiological genomics.

The effect of thin filament activation on the attachment of weak binding cross-bridges: A two-dimensional x-ray diffraction study on single muscle fibers.

B. Brenner, T. Kraft, L. Yu, 1999, Biophysical journal.

Ca2+-sensitive cross-bridge dissociation in the presence of magnesium pyrophosphate in skinned rabbit psoas fibers.

E. Eisenberg, B. Brenner, L. Greene, 1986, Biophysical journal.

Mechanical properties of single myosin molecules probed with the photonic force microscope.

Massimo Antognozzi, Tim Scholz, Christian Tischer, 2005, Biophysical journal.

X-ray diffraction testing for weak-binding crossbridges in relaxed bony fish muscle fibres at low ionic strength.

B. Brenner, J. Squire, R. J. Podolsky, 1991, Journal of structural biology.

X-ray diffraction studies of cross-bridges weakly bound to actin in relaxed skinned fibers of rabbit psoas muscle.

B. Brenner, D. Gilroy, T. Kraft, 1997, Biophysical journal.

Cross-bridge binding to actin and force generation in skinned fibers of the rabbit psoas muscle in the presence of antibody fragments against the N-terminus of actin.

B. Brenner, G. Dasgupta, E. Reisler, 1996, Biophysical journal.

Distinct molecular processes associated with isometric force generation and rapid tension recovery after quick release.

B. Brenner, J. Chalovich, L. Yu, 1995, Biophysical journal.

Interference of Myosin Peptides with Weak and Strong Actin Interaction of Cross-Bridges in Skeletal Muscle Fibres

B. Brenner, I. Trayer, T. Kraft, 1991 .

Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy

B. Brenner, C. D. dos Remedios, B. Keyser, 2017, Journal of Muscle Research and Cell Motility.

Tau Protein Diffuses along the Microtubule Lattice*

Tim Scholz, E. Mandelkow, B. Brenner, 2012, The Journal of Biological Chemistry.

Two independent switches regulate cytoplasmic dynein’s processivity and directionality

B. Brenner, M. Koonce, W. Steffen, 2012, Proceedings of the National Academy of Sciences.

1 Tau protein diffuses along the microtubule lattice

E. Mandelkow, B. Brenner, Satish Kumar, 2012 .

Cytoplasmic dynein is not a conventional processive motor.

B. Brenner, W. Steffen, Wilhelm J. Walter, 2010, Journal of structural biology.

Cardiomyopathy mutations reveal variable region of myosin converter as major element of cross-bridge compliance.

B. Brenner, W. McKenna, A. Perrot, 2009, Biophysical journal.

A laser diffraction method for measuring muscle sarcomere length in vivo for application to tendon transfers.

B. Brenner, R. J. Podolsky, J. P. Adams, 1985, The Journal of hand surgery.

Successful knock-in of Hypertrophic Cardiomyopathy-mutation R723G into the MYH7 gene mimics HCM pathology in pigs

B. Brenner, G. Cost, H. Niemann, 2018, Scientific Reports.

Burst-Like Transcription of Mutant and Wildtype MYH7-Alleles as Possible Origin of Cell-to-Cell Contractile Imbalance in Hypertrophic Cardiomyopathy

B. Brenner, C. D. dos Remedios, B. Keyser, 2018, Front. Physiol..

Sarcomeric domain organization within single skinned rabbit psoas fibers and its effects on laser light diffraction patterns.

B. Brenner, 1985, Biophysical journal.

Characterization of radial force and radial stiffness in Ca(2+)‐activated skinned fibres of the rabbit psoas muscle.

B. Brenner, B Brenner, L C Yu, 1991, The Journal of physiology.

On the regeneration of the actin-myosin power stroke in contracting muscle.

B. Brenner, Y. Chen, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Hypertrophic Cardiomyopathy: Cell-to-Cell Imbalance in Gene Expression and Contraction Force as Trigger for Disease Phenotype Development.

B. Brenner, T. Kraft, J. Montag, 2016, Circulation research.

Rapid dissociation and reassociation of actomyosin cross-bridges during force generation: a newly observed facet of cross-bridge action in muscle.

B. Brenner, Bernhard Brenner, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Modulation of cross-bridge affinity for MgGTP by Ca2+ in skinned fibers of rabbit psoas muscle.

B. Brenner, J. Chalovich, L. Yu, 1997, Biophysical journal.

Cross-bridge attachment during high-speed active shortening of skinned fibers of the rabbit psoas muscle: implications for cross-bridge action during maximum velocity of filament sliding.

B. Brenner, R. Stehle, 2000, Biophysical journal.

Familial hypertrophic cardiomyopathy: functional variance among individual cardiomyocytes as a trigger of FHC-phenotype development

B. Brenner, T. Kraft, J. Montag, 2014, Front. Physiol..

Mutation of the myosin converter domain alters cross-bridge elasticity

B. Brenner, W. McKenna, I. Schulte, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Driving filament sliding: weak binding cross-bridge states, strong binding cross-bridge states, and the power stroke.

B. Brenner, T. Kraft, E. Mählmann, 2005, Advances in experimental medicine and biology.

Effect of Ca2+ on weak cross-bridge interaction with actin in the presence of adenosine 5'-[gamma-thio]triphosphate).

B. Brenner, H. J. Kuhn, T. Kraft, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy

B. Brenner, C. D. dos Remedios, B. Keyser, 2017, Journal of Muscle Research and Cell Motility.

High-resolution equatorial x-ray diffraction from single skinned rabbit psoas fibers.

B. Brenner, L. Yu, 1986, Biophysical journal.

Initiation of the power stroke in muscle: insights from the phosphate analog AlF4.

B. Brenner, T. Kraft, E. Mählmann, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Inorganic Phosphate Binds to the Empty Nucleotide Binding Pocket of Conventional Myosin II*

M. Antognozzi, B. Brenner, H. Kojima, 2008, Journal of Biological Chemistry.

Equatorial x-ray diffraction from single skinned rabbit psoas fibers at various degrees of activation. Changes in intensities and lattice spacing.

B. Brenner, B Brenner, L C Yu, 1985, Biophysical journal.

Cross bridge attachment during isotonic shortening in single skinned rabbit psoas fibers

B. Brenner, 1983 .

Mechanical and structural approaches to correlation of cross-bridge action in muscle with actomyosin ATPase in solution.

B. Brenner, 1987, Annual review of physiology.

Acto-myosin cross-bridge stiffness depends on the nucleotide state of the myosin II

B. Brenner, Mamta Amrute-Nayak, A. Nayak, 2020, bioRxiv.

A force transducer for measuring mechanical properties of single cardiac myocytes.

C. Tasche, E. Meyhöfer, B. Brenner, 1999, The American journal of physiology.

Stiffness of skinned rabbit psoas fibers in MgATP and MgPPi solution.

E. Eisenberg, B. Brenner, L. Greene, 1986, Biophysical journal.

Muscle mechanics II: skinned muscle fibres

B. Brenner, 1998 .

A new concept for the mechanism of Ca+(+)-regulation of muscle contraction. Implications for physiological and pharmacological approaches to modulate contractile function of myocardium.

B. Brenner, 1991, Basic research in cardiology.

Special topic: molecular mechanism of muscle contraction. General introduction.

B. Brenner, Y. Goldman, 1987, Annual review of physiology.

Force-generating cross-bridges during ramp-shaped releases: evidence for a new structural state.

B. Brenner, T. Weiss, T. Kraft, 2009, Biophysical journal.

Thin filament activation probed by fluorescence of N-((2-(iodoacetoxy)ethyl)-N-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole-labeled troponin I incorporated into skinned fibers of rabbit psoas muscle.

B. Brenner, J. Chalovich, T. Kraft, 1999, Biophysical journal.

Comparison of Clinical Performance, Histology and Single-Fiber Contractility in Free Neurovascular Muscle Flaps

B. Brenner, G. F. Walter, A. Berger, 2000, Journal of reconstructive microsurgery.

Structural features of cross-bridges in isometrically contracting skeletal muscle.

B. Brenner, T. Kraft, B. Piep, 2002, Biophysical journal.

Efficient Knock-in of a Point Mutation in Porcine Fibroblasts Using the CRISPR/Cas9-GMNN Fusion Gene

B. Brenner, H. Niemann, B. Petersen, 2018, Genes.

Structural Features of Force-Generating Cross-Bridges

B. Brenner, T. Kraft, T. Mattei, 1998 .

Advanced Single-Cell Mapping Reveals that in hESC Cardiomyocytes Contraction Kinetics and Action Potential Are Independent of Myosin Isoform

B. Chichkov, B. Brenner, A. Haverich, 2020, Stem cell reports.

The stroke size of myosins: a reevaluation

B. Brenner, Bernhard Brenner, 2006, Journal of Muscle Research & Cell Motility.

Structural changes in the actomyosin cross-bridges associated with force generation.

B. Brenner, L. Yu, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The cross-bridge cycle in muscle. Mechanical, biochemical, and structural studies on single skinned rabbit psoas fibers to characterize cross-bridge kinetics in muscle for correlation with the actomyosin-ATPase in solution.

B. Brenner, B Brenner, 1986, Basic research in cardiology.

Acto-myosin cross-bridge stiffness depends on the nucleotide state of the myosin II.

B. Brenner, Mamta Amrute-Nayak, A. Nayak, 2020, Nano letters.

A single-fiber in vitro motility assay. In vitro sliding velocity of F-actin vs. unloaded shortening velocity in skinned muscle fibers

B. Brenner, E. Thedinga, T. Kraft, 1999, Journal of Muscle Research & Cell Motility.

The mechanism of muscle contraction. Biochemical, mechanical, and structural approaches to elucidate cross-bridge action in muscle.

E. Eisenberg, B. Brenner, B Brenner, 1987, Basic research in cardiology.

ATP turnover by individual myosin molecules hints at two conformers of the myosin active site

B. Brenner, G. Tsiavaliaris, Wilhelm J. Walter, 2014, Proceedings of the National Academy of Sciences.

Two independent switches regulate cytoplasmic dynein’s processivity and directionality

B. Brenner, M. Koonce, W. Steffen, 2012, Proceedings of the National Academy of Sciences.

Evidence for structural changes in crossbridges during force generation.

B. Brenner, L. Yu, 1993, Advances in experimental medicine and biology.

Dynamic actin interaction of crossbridges: a general principle and its implications for crossbridge action in muscle.

B. Brenner, 1991, Advances in biophysics.