M. Bühler

发表

Single Cell RNA-Sequencing of Pluripotent States Unlocks Modular Transcriptional Variation

Aleksandra A. Kolodziejczyk, S. Teichmann, J. Marioni, 2015, Cell stem cell.

Alternative splicing induced by nonsense mutations in the immunoglobulin mu VDJ exon is independent of truncation of the open reading frame.

O. Mühlemann, M. Bühler, 2005, RNA.

Nuclear organisation and RNAi in fission yeast.

M. Bühler, K. Woolcock, 2013, Current opinion in cell biology.

A fully automated deep learning pipeline for high-throughput colony segmentation and classification

M. Bühler, S. Carl, Y. Shimada, 2020, Biology Open.

Distinctive features of lincRNA gene expression suggest widespread RNA-independent functions

S. Teichmann, K. Natarajan, A. Tuck, 2018, Life Science Alliance.

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse

M. Bühler, Fabio Mohn, Elzo de Wit, 2019, Cell.

Tramp-mediated Rna Surveillance Prevents Spurious Entry of Rnas into the Schizosaccharomyces Pombe Sirna Pathway Nih Public Access Author Manuscript Gene-specific Srnas Methods Fission Yeast Strains and Plasmids Generation of Small Rna Libraries for 454 Deep Sequencing Supplementary Material Acknowl

Noah Spies, Marc Bühler, D. Bartel, 2022 .

Dynamic nature of heterochromatin highlighted by a HP1Swi6-dependent gene silencing mechanism

M. Bühler, S. Hiller, 2012, Cell cycle.

EJC-independent degradation of nonsense immunoglobulin-μ mRNA depends on 3′ UTR length

Alexandra Paillusson, O. Mühlemann, M. Bühler, 2006, Nature Structural &Molecular Biology.

Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes

M. Bühler, Fabio Mohn, D. Hess, 2018, Nature.

Mammalian RNA Decay Pathways Are Highly Specialized and Widely Linked to Translation

A. Tuck, M. Bühler, D. Gatfield, 2020, Molecular cell.

Intranuclear degradation of nonsense codon‐containing mRNA

O. Mühlemann, M. Bühler, M. Wilkinson, 2002, EMBO reports.

The RNA-induced transcriptional silencing complex targets chromatin exclusively via interacting with nascent transcripts

M. Bühler, Fabio Mohn, Y. Shimada, 2016, Genes & development.

Disruption of an RNA-binding hinge region abolishes LHP1-mediated epigenetic repression

C. Dean, M. Bühler, M. Howard, 2017, Genes & development.

Small RNAs in the Transgenerational Inheritance of Epigenetic Information.

M. Bühler, Lea Duempelmann, Merle Skribbe, 2020, Trends in genetics : TIG.

Chromatin-associated ncRNA activities

M. Bühler, C. Keller, 2013, Chromosome Research.

Differential phosphorylation of Clr4SUV39H by Cdk1 accompanies a histone H3 methylation switch that is essential for gametogenesis

M. Bühler, D. Hess, Valentin Flury, 2022, EMBO reports.

The Paf1 complex represses small RNA-mediated epigenetic gene silencing

Michael B. Stadler, M. Bühler, Júlia Batki, 2015, Nature.

Nuclear retention of fission yeast dicer is a prerequisite for RNAi-mediated heterochromatin assembly.

M. Bühler, Tim C. Roloff, Dimos Gaidatzis, 2010, Developmental cell.

Silent chromatin at the middle and ends: lessons from yeasts

S. Gasser, M. Bühler, 2009, The EMBO journal.

Transcription and RNAi in heterochromatic gene silencing

D. Moazed, M. Bühler, 2007, Nature Structural &Molecular Biology.

RNAi-Dependent and -Independent RNA Turnover Mechanisms Contribute to Heterochromatic Gene Silencing

Steven P. Gygi, Wilhelm Haas, Marc Bühler, 2007, Cell.

Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast

S. Gygi, J. Villén, D. Moazed, 2007, Nature Structural &Molecular Biology.

Tethering RITS to a Nascent Transcript Initiates RNAi- and Heterochromatin-Dependent Gene Silencing

Marc Bühler, D. Moazed, M. Bühler, 2006, Cell.

Regulation of Transcription through Acetylation of H3K122 on the Lateral Surface of the Histone Octamer

Edison T. Liu, Marc Bühler, E. Liu, 2013, Cell.

Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon.

Alexandra Paillusson, O. Mühlemann, M. Bühler, 2004, Nucleic acids research.

RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding

C. Niehrs, M. Bühler, M. Musheev, 2017, Nature Structural &Molecular Biology.

HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts.

M. Bühler, K. Woolcock, S. Hiller, 2012, Molecular cell.

Studies on the mechanism of RNAi-dependent heterochromatin assembly.

S. Gygi, J. Villén, D. Moazed, 2006, Cold Spring Harbor symposia on quantitative biology.

An extended dsRBD with a novel zinc-binding motif mediates nuclear retention of fission yeast Dicer

H. Hotz, M. Bühler, Y. Shimada, 2011, The EMBO journal.

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d

Mark Helm, Miguel A Andrade-Navarro, Marc Bühler, 2018, Genes & development.

Adenosine methylation as a molecular imprint defining the fate of RNA

M. Bühler, P. Knuckles, 2018, FEBS letters.

miR455 is linked to hypoxia signaling and is deregulated in preeclampsia

M. Bühler, S. Lalevée, O. Lapaire, 2014, Cell Death and Disease.

CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations

T. Bouwmeester, E. Oakeley, M. Bühler, 2016, Stem cell reports.

Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe

Dimos Gaidatzis, Marc Bühler, M. Bühler, 2011, Nature Structural &Molecular Biology.

m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin

Galina A. Erikson, T. Jenuwein, M. Bühler, 2021, Nucleic acids research.

Long Non-coding RNA Depletion Using Self-Cleaving Ribozymes.

A. Tuck, M. Bühler, 2021, Methods in molecular biology.

Chromatin-associated ncRNA activities

M. Bühler, C. Keller, 2013, Chromosome Research.

Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation

M. Bühler, T. Punga, 2010, EMBO molecular medicine.

Transcriptional silencing of nonsense codon-containing immunoglobulin minigenes.

O. Mühlemann, M. Bühler, Fabio Mohn, 2005, Molecular cell.

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1

M. Bühler, Sigurd Braun, Valentin Flury, 2017, Molecular cell.

Dicer and Hsp104 function in a negative feedback loop to confer robustness to environmental stress.

C. Genoud, D. Oberti, M. Kirschmann, 2015, Cell reports.

Nonsense-associated alternative splicing of T-cell receptor beta genes: no evidence for frame dependence.

O. Mühlemann, M. Bühler, Fabio Mohn, 2005, RNA.

RNA turnover and chromatin-dependent gene silencing

M. Bühler, 2009, Chromosoma.

Noncoding RNAs prevent spreading of a repressive histone mark

H. Hotz, M. Bühler, Y. Shimada, 2013, Nature Structural &Molecular Biology.

An enhancer screen identifies new suppressors of small-RNA-mediated epigenetic gene silencing

M. Bühler, S. Carl, Valentin Flury, 2021, PLoS genetics.

RNAi keeps Atf1-bound stress response genes in check at nuclear pores.

H. Hotz, M. Bühler, Dimos Gaidatzis, 2012, Genes & development.

Inheritance of a Phenotypically Neutral Epimutation Evokes Gene Silencing in Later Generations

D. Oberti, M. Bühler, Fabio Mohn, 2019, Molecular cell.

Genome-Engineering Tools to Establish Accurate Reporter Cell Lines That Enable Identification of Therapeutic Strategies to Treat Friedreich’s Ataxia

Buu P. Tu, L. Miraglia, M. Bühler, 2015, Journal of biomolecular screening.

H3K9 methylation extends across natural boundaries of heterochromatin in the absence of an HP1 protein

M. Kirschmann, M. Bühler, L. Gelman, 2015, The EMBO journal.

Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14.

M. Bühler, D. Hess, K. Woolcock, 2010, RNA.

Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes

M. Bühler, Fabio Mohn, D. Hess, 2018, Nature.

The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1

Panagiotis K. Papasaikas, A. Tuck, M. Bühler, 2019, Genes & development.

Noncoding RNAs prevent spreading of a repressive histone mark

Hans-Rudolf Hotz, Marc Bühler, H. Hotz, 2013, Nature Structural &Molecular Biology.

Single-Step Generation of Conditional Knockout Mouse Embryonic Stem Cells.

M. Bühler, Matyáš Flemr, 2015, Cell reports.

Zc 3 h 13 / Flacc is required for adenosine methylation by bridging the mRNA binding factor Rbm 15 / Spenito to the m 6 A machinery component Wtap / Fl ( 2 )

M. Bühler, Jean-Yves Roignant, M. Helm, 2018 .

Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus

I. Ulitsky, A. Tuck, M. Bühler, 2023, Cell reports.

A fully automated deep learning pipeline for high-throughput colony segmentation and classification

Sarah H. Carl, Lea Duempelmann, Yukiko Shimada, 2019, bioRxiv.

Scaling up dissection of functional RNA elements

A. Tuck, M. Bühler, 2020, Nature Structural & Molecular Biology.

TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway

D. Bartel, D. Moazed, Noah Spies, 2008, Nature structural & molecular biology.

TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway

D. Bartel, D. Moazed, Noah Spies, 2008, Nature Structural &Molecular Biology.

RNAi keeps Atf1-bound stress response genes in check at nuclear pores.

H. Hotz, M. Bühler, Dimos Gaidatzis, 2012, Genes & development.

Flacc is required for adenosine methylation by bridging the mRNA binding factor Rbm 15 / Spenito to the m 6 A machinery component Wtap / Fl ( 2 ) d

Hares, M. Bühler, Jean-Yves Roignant, 2018 .

A detour to mature.

M. Bühler, Rieka Stunnenberg, 2012, Molecular cell.

HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts.

M. Bühler, K. Woolcock, S. Hiller, 2012, Molecular cell.

Nitrogen signaling factor triggers a respiration-like gene expression program

M. Bühler, M. Sodeoka, Akihisa Matsuyama, 2023, bioRxiv.