S. Xiao

发表

Dynamic regulatory network controlling Th17 cell differentiation

A. Regev, John J. Trombetta, Diana Lu, 2013, Nature.

Induction and molecular signature of pathogenic TH17 cells

A. Regev, N. Yosef, D. Hafler, 2012, Nature Immunology.

Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.

Mark S. Sundrud, A. Regev, R. Young, 2014, Immunity.

Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1

A. Regev, N. Yosef, Chuan Wu, 2013, Nature.

Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis.

A. McMahon, V. Kuchroo, S. Xiao, 2013, The Journal of clinical investigation.

KIM-1-mediated phagocytosis reduces acute injury to the kidney.

L. Hsiao, V. Kuchroo, S. Xiao, 2015, Journal of Clinical Investigation.

TIM‐1 Signaling Is Required for Maintenance and Induction of Regulatory B Cells

V. Kuchroo, S. Xiao, C. Brooks, 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Combining Fas Mutation with Interleukin-2 Deficiency Prevents Colitis and Lupus

S. Xiao, S. Ju, S. Sung, 2003, Journal of Biological Chemistry.

Glucose-induced phosphorylation of the insulin receptor. Functional effects and characterization of phosphorylation sites.

S. Xiao, J. Olefsky, T. S. Pillay, 1996, The Journal of clinical investigation.

8-chloroadenosine induces apoptosis in human MOLT-4 cell line

S. Xiao, Rui Liu, Lihe Zhang, 1997 .

Changes in sensitivity of peripheral lymphocytes of autoimmune gld mice to FasL-mediated apoptosis reveal a mechanism for the preferential deletion of CD4-CD8-B220+ T cells.

S. Xiao, S. Ju, A. Marshak‐Rothstein, 2004, International immunology.

Hypothesis: A Recurrent, Moderate Activation Fosters Systemic Autoimmunity – The Apoptotic Roles of TCR, IL-2 and Fas Ligand

S. Xiao, S. Ju, S. Jodo, 1999, Journal of Biomedical Science.

Hypothesis: A recurrent, moderate activation fosters systemic autoimmunity--the apoptotic roles of TCR, IL-2 and Fas ligand.

S. Xiao, S. Ju, S. Jodo, 1999, Journal of biomedical science.

KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease.

V. Kuchroo, S. Xiao, J. Bonventre, 2021, Cell metabolism.

CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis.

V. Kuchroo, S. Khoury, S. Xiao, 2007, Journal of immunology.

Anti-CD95-induced lethality requires radioresistant Fcgamma RII+ cells. A novel mechanism for fulminant hepatic failure.

S. Xiao, R. Lafyatis, S. Ju, 2003, The Journal of biological chemistry.

Robust tumor immunity to melanoma mediated by interleukin 9

R. Clark, V. Kuchroo, S. Khoury, 2012, Nature Medicine.

Plasticity of Ly-6Chi Myeloid Cells in T Cell Regulation

Chuan Wu, S. Khoury, S. Xiao, 2011, The Journal of Immunology.

Regulation Myeloid Cells in T Cell hi Plasticity of Ly-6C

Chuan Wu, S. Xiao, B. Zhu, 2022 .

Novel Negative Regulator of Expression in Fas Ligand (CD178) Cytoplasmic Tail: Evidence for Translational Regulation and against Fas Ligand Retention in Secretory Lysosomes1

S. Xiao, S. Ju, T. Koike, 2004, The Journal of Immunology.

Enhancement of Cytotoxicity Display Antibody-Mediated , FcR-Dependent CD 95 ( Fas ) Ligand-Expressing Vesicles

S. Xiao, S. Ju, A. Marshak‐Rothstein, 2000 .

Tim‐1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells

V. Kuchroo, Hulin Jin, S. Xiao, 2011, European journal of immunology.

Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1

A. Regev, N. Yosef, Chuan Wu, 2013, Nature.

Apoptosis-inducing Membrane Vesicles

S. Xiao, S. Ju, A. Marshak‐Rothstein, 2001, The Journal of Biological Chemistry.

New roles for TIM family members in immune regulation

V. Kuchroo, S. Xiao, V. Dardalhon, 2008, Nature Reviews Immunology.

Tim-2 regulates T helper type 2 responses and autoimmunity

V. Kuchroo, R. Sobel, S. Xiao, 2005, The Journal of experimental medicine.

A Novel Signaling Mechanism for Soluble CD95 Ligand

S. Xiao, S. Ju, A. Marshak‐Rothstein, 2002, The Journal of Biological Chemistry.

Cutting Edge: Fas Ligand (CD178) Cytoplasmic Tail Is a Positive Regulator of Fas Ligand-Mediated Cytotoxicity1

S. Xiao, S. Ju, T. Koike, 2005, The Journal of Immunology.

IL-4 and Retinoic Acid Synergistically Induce Regulatory Dendritic Cells Expressing Aldh1a2

Chuan Wu, S. Khoury, S. Xiao, 2013, The Journal of Immunology.

Aldh1a2Regulatory Dendritic Cells Expressing IL-4 and Retinoic Acid Synergistically Induce

Chuan Wu, S. Khoury, S. Xiao, 2013 .

Two tyrosines in CD3s-ITAM are required to induce T lymphocyte apoptosis

S. Xiao, Yiping He, D. Zheng, 1998 .

Cloning and identification of a novel binding protein of CD2 cytoplasmic domain

Dong Li, S. Xiao, D. Zheng, 2000 .

Retinoic Acid Increases Foxp3+ Regulatory T Cells and Inhibits Development of Th17 Cells by Enhancing TGF-β-Driven Smad3 Signaling and Inhibiting IL-6 and IL-23 Receptor Expression1

B. Lim, V. Kuchroo, Hulin Jin, 2008, The Journal of Immunology.

CD11b+Ly-6Chi Suppressive Monocytes in Experimental Autoimmune Encephalomyelitis1

V. Kuchroo, S. Khoury, S. Xiao, 2007, The Journal of Immunology.

Foxo1 controls gut homeostasis and commensalism by regulating mucus secretion

B. Bao, Chuan Wu, V. Kuchroo, 2021, The Journal of experimental medicine.

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

A. Regev, N. Yosef, A. Madi, 2015, Cell.

Tim-1 Is Essential for Induction and Maintenance of IL-10 in Regulatory B Cells and Their Regulation of Tissue Inflammation

V. Kuchroo, R. Sobel, S. Xiao, 2015, The Journal of Immunology.

Their Regulation of Tissue Inflammation Maintenance of IL-10 in Regulatory B Cells Tim-1 Is Essential for Induction and

R. Sobel, S. Xiao, C. Brooks, 2015 .

TIM-3 restrains anti-tumour immunity by regulating inflammasome activation

A. Regev, M. Tabaka, O. Rozenblatt-Rosen, 2021, Nature.

Aiolos promotes TH17 differentiation by directly silencing Il2 expression

J. Seavitt, V. Kuchroo, Hulin Jin, 2012, Nature Immunology.

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells.

Chuan Wu, V. Kuchroo, S. Xiao, 2014, Immunity.

Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses.

C. Benoist, D. Hafler, V. Kuchroo, 2014, Immunity.

SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells

A. Madi, Chuan Wu, V. Kuchroo, 2018, Cell reports.

VentX trans-Activates p53 and p16ink4a to Regulate Cellular Senescence

S. Xiao, M. Hager, M. Freeman, 2011, The Journal of Biological Chemistry.

Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion

A. Regev, T. Mak, V. Kuchroo, 2021, Science Advances.

Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

A. Regev, N. Yosef, Jellert Gaublomme, 2016, The Journal of experimental medicine.

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

D. Green, H. Weiner, V. Kuchroo, 2010, Proceedings of the National Academy of Sciences.

TIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunity.

V. Kuchroo, S. Xiao, B. Rossi, 2014, Immunity.

Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion

Sheng Xiao, Ana C Anderson, Chen Zhu, 2012, Nature Medicine.

RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression.

A. Regev, Le Cong, Youjin Lee, 2016, Cell reports.

Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.

D. Hafler, A. Marson, V. Kuchroo, 2014, The Journal of clinical investigation.

The Aryl hydrocarbon Receptor (AhR) interacts with c-Maf to promote the differentiation of IL-27-induced regulatory type 1 (TR1) cells

H. Weiner, V. Kuchroo, S. Xiao, 2010, Nature Immunology.

Metallothioneins negatively regulate IL-27–induced type 1 regulatory T-cell differentiation

N. Yosef, Youjin Lee, Chuan Wu, 2013, Proceedings of the National Academy of Sciences.

Bat3 Protects T cell Responses by Repressing Tim-3-Mediated Exhaustion and Death

T. Mak, M. Addo, V. Kuchroo, 2012 .

The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program

A. Madi, Chuan Wu, V. Kuchroo, 2017, Nature Immunology.

An IL-27/NFIL3 signaling axis drives Tim-3 and IL-10 expression and T cell dysfunction

R. Ahmed, Chuan Wu, V. Kuchroo, 2015, Nature Communications.

Induction and molecular signature of pathogenic T[subscript H]17 cells

A. Regev, N. Yosef, D. Hafler, 2012 .

IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis.

Youjin Lee, V. Kuchroo, R. Sobel, 2015, The Journal of clinical investigation.

Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice

Chuan Wu, V. Kuchroo, R. Sobel, 2012, Proceedings of the National Academy of Sciences.

Sp1 is the major fasl gene activator in abnormal CD4–CD8–B220+ T cells of lpr and gld mice

S. Xiao, S. Ju, A. Marshak‐Rothstein, 2001, European journal of immunology.

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

V. Kuchroo, R. Sobel, S. Khoury, 2007, The Journal of experimental medicine.

Diff erential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and eff ector function

V. Kuchroo, R. Sobel, S. Khoury, 2007 .

Receptor Expression Signaling and Inhibiting IL-6 and IL-23 -Driven Smad3 b by Enhancing TGF-Cells and Inhibits Development of Th17 Cells Regulatory T + Retinoic Acid Increases Foxp3

B. Lim, V. Kuchroo, Hulin Jin, 2008 .

Encephalomyelitis Experimental Autoimmune Suppressive Monocytes in Hi Ly-6c + Cd11b

V. Kuchroo, S. Khoury, S. Xiao, 2022 .

Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation.

N. Pochet, H. Weiner, A. Madi, 2020, Cell reports.

SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells

A. Madi, Chuan Wu, V. Kuchroo, 2018, Cell reports.

Tiam1/Rac1 complex controls Il17a transcription and autoimmunity

Chuan Wu, S. Khoury, S. Xiao, 2016, Nature Communications.

Tim Protein Structures Reveal a Unique Face for Ligand Binding

V. Kuchroo, S. Xiao, A. Anderson, 2007, Immunity.

Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1 (P1145)

A. Regev, N. Yosef, Chuan Wu, 2013, The Journal of Immunology.

B-cell-specific checkpoint molecules that regulate anti-tumour immunity

A. Regev, O. Rozenblatt-Rosen, V. Kuchroo, 2023, Nature.

KIM-1-mediated phagocytosis reduces acute injury to the kidney.

L. Hsiao, V. Kuchroo, S. Xiao, 2015, The Journal of clinical investigation.

Plasticity of Ly-6Chi Myeloid Cells in T Cell Regulation

Chuan Wu, S. Khoury, S. Xiao, 2011, The Journal of Immunology.

Regulation Myeloid Cells in T Cell Hi Plasticity of Ly-6c

Chuan Wu, S. Xiao, W. Elyaman, 2022 .