M. Eszlinger

发表

Nonparametric multiple test procedures with data-driven order of hypotheses and with weighted hypotheses

R. Paschke, S. Kropf, J. Läuter, 2004 .

Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation

Rosalind J Wright, R. Eils, C. Plass, 2016, Scientific Reports.

Tobacco smoking differently influences cell types of the innate and adaptive immune system—indications from CpG site methylation

M. Eszlinger, I. Lehmann, G. Herberth, 2016, Clinical Epigenetics.

Molecular Testing of Nodules with a Suspicious or Malignant Cytologic Diagnosis in the Setting of Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP)

R. Paschke, N. Lindeman, M. Eszlinger, 2018, Endocrine Pathology.

Fine-needle aspiration diagnoses of noninvasive follicular variant of papillary thyroid carcinoma.

R. Paschke, M. Eszlinger, J. Barletta, 2015, American journal of clinical pathology.

Gene Expression (mRNA) Markers for Differentiating between Malignant and Benign Follicular Thyroid Tumours

Tomasz Stokowy, Steffen Hauptmann, Michal Jarzab, 2017, International journal of molecular sciences.

Molecular differential diagnosis of follicular thyroid carcinoma and adenoma based on gene expression profiling by using formalin-fixed paraffin-embedded tissues

R. Paschke, S. Hauptmann, M. Eszlinger, 2013, BMC Medical Genomics.

Analysis options for high-throughput sequencing in miRNA expression profiling

Krzysztof Fujarewicz, Tomasz Stokowy, Knut Krohn, 2014, BMC Research Notes.

Comparison of Independent Samples of High‐Dimensional Data by Pairwise Distance Measures

H. Heuer, S. Kropf, M. Eszlinger, 2007, Biometrical journal. Biometrische Zeitschrift.

Gene expression analysis reveals evidence for increased expression of cell cycle-associated genes and Gq-protein-protein kinase C signaling in cold thyroid nodules.

Jürgen Läuter, Siegfried Kropf, Knut Krohn, 2005, The Journal of clinical endocrinology and metabolism.

Adiponectin gene expression is inhibited by β‐adrenergic stimulation via protein kinase A in 3T3‐L1 adipocytes

R. Paschke, J. Klein, M. Fasshauer, 2001, FEBS letters.

Isoproterenol inhibits resistin gene expression through a GS‐protein‐coupled pathway in 3T3‐L1 adipocytes

R. Paschke, J. Klein, M. Fasshauer, 2001, FEBS letters.

The genetics of euthyroid familial goiter

R. Paschke, Y. Böttcher, M. Eszlinger, 2005, Trends in Endocrinology & Metabolism.

Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes.

R. Paschke, J. Klein, M. Fasshauer, 2002, Biochemical and biophysical research communications.

Tumor Necrosis Factor α Is a Negative Regulator of Resistin Gene Expression and Secretion in 3T3-L1 Adipocytes

R. Paschke, J. Klein, M. Fasshauer, 2001 .

A two miRNA classifier differentiates follicular thyroid carcinomas from follicular thyroid adenomas

R. Paschke, L. Hegedüs, M. Eszlinger, 2015, Molecular and Cellular Endocrinology.

Impact of molecular screening for point mutations and rearrangements in routine air-dried fine-needle aspiration samples of thyroid nodules.

R. Paschke, L. Hegedüs, M. Scholz, 2014, Thyroid : official journal of the American Thyroid Association.

Detection of PAX8/PPARG and RET/PTC rearrangements is feasible in routine air-dried fine needle aspiration smears.

R. Paschke, L. Hegedüs, M. Eszlinger, 2012, Thyroid : official journal of the American Thyroid Association.

Somatostatin receptor 2 expression determined by immunohistochemistry in cold thyroid nodules exceeds that of hot thyroid nodules, papillary thyroid carcinoma, and Graves' disease.

R. Paschke, M. Eszlinger, B. Güllüoğlu, 2010, Thyroid : official journal of the American Thyroid Association.

Low Malignancy Rates in Fine-Needle Aspiration Cytologies in a Primary Care Setting in Germany.

R. Paschke, C. Franzius, M. Eszlinger, 2017, Thyroid : official journal of the American Thyroid Association.

Systematic population-based identification of NTRK and RET fusion-positive thyroid cancers

R. Paschke, Moosa Khalil, M. Eszlinger, 2021, European thyroid journal.

Hyperthyroidism and Papillary Thyroid Carcinoma in Thyrotropin Receptor D633H Mutant Mice.

R. Paschke, J. Toppari, Moosa Khalil, 2018, Thyroid : official journal of the American Thyroid Association.

Young investigator challenge: Can the Ion AmpliSeq Cancer Hotspot Panel v2 be used for next‐generation sequencing of thyroid FNA samples?

R. Paschke, M. Eszlinger, G. Troncone, 2016, Cancer cytopathology.

TERT Promoter Mutations in Papillary Thyroid Microcarcinomas.

R. Paschke, M. Eszlinger, S. Filetti, 2015, Thyroid : official journal of the American Thyroid Association.

PAX8/PPARG and RET/PTC rearrangement detection is feasible in routine air dried fine needle aspiration (FNA) smears

R. Paschke, L. Hegedüs, M. Eszlinger, 2012 .

Clinical implications of molecular studies for the diagnosis of thyroid cancer

R. Paschke, M. Eszlinger, K. Schmid, 2010, Hormones.

Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas.

R. Paschke, T. Strom, T. Schwarzmayr, 2016, The Journal of clinical investigation.

Tumor necrosis factor alpha is a negative regulator of resistin gene expression and secretion in 3T3-L1 adipocytes.

R. Paschke, J. Klein, M. Fasshauer, 2001, Biochemical and biophysical research communications.

Cellularity and Adipogenic Profile of the Abdominal Subcutaneous Adipose Tissue From Obese Adolescents: Association With Insulin Resistance and Hepatic Steatosis

Samuel W. Cushman, Arthur Sherman, Sonia Caprio, 2010, Diabetes.

Molecular analysis of residual ThinPrep material from thyroid FNAs increases diagnostic sensitivity

R. Paschke, M. Eszlinger, E. Alexander, 2015, Cancer cytopathology.

RGS 2 expression is regulated by TSH and inhibits TSH receptor signaling.

R. Paschke, M. Eszlinger, Cord Arkenau, 2004, European journal of endocrinology.

Prolonged Inappropriate TSH Suppression During Hypothyroidism After Thyroid Ablation in a Patient with Nonautoimmune Familial Hyperthyroidism

R. Paschke, M. Eszlinger, H. Jaeschke, 2011, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Thyroglobulin mRNA quantification in the peripheral blood is not a reliable marker for the follow-up of patients with differentiated thyroid cancer.

R. Paschke, M. Eszlinger, S. Neumann, 2002, European journal of endocrinology.

Insights from molecular pathways: potential pharmacologic targets of benign thyroid nodules

R. Paschke, M. Eszlinger, H. Jaeschke, 2007, Current opinion in endocrinology, diabetes, and obesity.

A newly discovered TSHR variant (L665F) associated with nonautoimmune hyperthyroidism in an Austrian family induces constitutive TSHR activation by steric repulsion between TM1 and TM7.

R. Paschke, J. Meiler, M. Eszlinger, 2014, The Journal of clinical endocrinology and metabolism.

Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas

R. Paschke, M. Eszlinger, S. Mueller, 2010, Clinical endocrinology.

Accuracy of Thyroid Fine-Needle Aspiration Cytology: A Cyto-Histologic Correlation Study in an Integrated Canadian Health Care Region with Centralized Pathology Service

R. Paschke, Moosa Khalil, M. Eszlinger, 2022, Acta Cytologica.

Shared sporadic and somatic thyrotropin receptor mutations display more active in vitro activities than familial thyrotropin receptor mutations.

R. Paschke, M. Eszlinger, S. Mueller, 2011, Thyroid : official journal of the American Thyroid Association.

Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid.

M. Eszlinger, K. Krohn, C. Ihling, 2012, The international journal of biochemistry & cell biology.

Expression of regulators of g protein signaling mRNA is differentially regulated in hot and cold thyroid nodules.

R. Paschke, M. Eszlinger, A. Tönjes, 2004, Thyroid : official journal of the American Thyroid Association.

Calcium signaling of thyrocytes is modulated by TSH through calcium binding protein expression.

R. Paschke, M. Eszlinger, K. Krohn, 2010, Biochimica et biophysica acta.

Warthin-Like Papillary Thyroid Microcarcinoma With Coincidental Ipsilateral Warthin Tumor of the Parotid Gland Detected on 131I-SPECT/US and 18F-PET/US Fusion Imaging.

M. Eszlinger, A. Werner, P. Seifert, 2022, Clinical nuclear medicine.

Molecular pathogenesis of euthyroid and toxic multinodular goiter.

R. Paschke, M. Eszlinger, K. Krohn, 2005, Endocrine reviews.

Complementary DNA expression array analysis suggests a lower expression of signal transduction proteins and receptors in cold and hot thyroid nodules.

R. Paschke, M. Eszlinger, K. Krohn, 2001, The Journal of clinical endocrinology and metabolism.

Effect of iodine on early stage thyroid autonomy.

M. Eszlinger, K. Krohn, D. Führer, 2011, Genomics.

A multi-gene approach to differentiate papillary thyroid carcinoma from benign lesions: gene selection using support vector machines with bootstrapping

Krzysztof Fujarewicz, Andrzej Świerniak, Knut Krohn, 2007, Endocrine-related cancer.

Perspectives and limitations of microarray-based gene expression profiling of thyroid tumors.

R. Paschke, M. Eszlinger, K. Krohn, 2007, Endocrine reviews.

Meta- and reanalysis of gene expression profiles of hot and cold thyroid nodules and papillary thyroid carcinoma for gene groups.

Krzysztof Fujarewicz, Andrzej Swierniak, Jürgen Läuter, 2006, The Journal of clinical endocrinology and metabolism.

Molecular profiling of thyroid nodule fine-needle aspiration cytology

R. Paschke, Moosa Khalil, M. Eszlinger, 2017, Nature Reviews Endocrinology.

Molecular testing of thyroid fine-needle aspirations improves presurgical diagnosis and supports the histologic identification of minimally invasive follicular thyroid carcinomas.

R. Paschke, M. Eszlinger, S. Piana, 2015, Thyroid : official journal of the American Thyroid Association.

Molecular Diagnosis Using Residual Liquid-Based Cytology Materials for Patients with Nondiagnostic or Indeterminate Thyroid Nodules

Tae Yong Kim, Won Gu Kim, R. Paschke, 2016, Endocrinology and metabolism.

Dissecting molecular events in thyroid neoplasia provides evidence for distinct evolution of follicular thyroid adenoma and carcinoma.

M. Eszlinger, K. Schmid, C. Ihling, 2011, The American journal of pathology.

A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood

U. Sack, M. Eszlinger, G. Herberth, 2015, Clinical Epigenetics.

Current state and future perspective of molecular diagnosis of fine-needle aspiration biopsy of thyroid nodules.

R. Paschke, M. Eszlinger, C. Ferraz, 2011, The Journal of clinical endocrinology and metabolism.

Molecular differential diagnosis of follicular thyroid carcinoma and adenoma based on gene expression profiling by using formalin-fixed paraffin-embedded tissues

R. Paschke, S. Hauptmann, M. Eszlinger, 2013, BMC Medical Genomics.

Somatic mutations in 33 benign and malignant hot thyroid nodules in children and adolescents

R. Paschke, M. Eszlinger, K. Krohn, 2014, Molecular and Cellular Endocrinology.

Sensitive Sequencing Analysis Suggests Thyrotropin Receptor and Guanine Nucleotide-Binding Protein G Subunit Alpha as Sole Driver Mutations in Hot Thyroid Nodules

R. Paschke, M. Eszlinger, K. Krohn, 2020 .

High Prevalence of TSHR/Gsα Mutation-negative Clonal Hot Thyroid Nodules (HNs) in a Turkish Cohort

R. Paschke, M. Eszlinger, S. Sancak, 2011, Hormone and Metabolic Research.

Molecular fine-needle aspiration biopsy diagnosis of thyroid nodules by tumor specific mutations and gene expression patterns

R. Paschke, M. Eszlinger, 2010, Molecular and Cellular Endocrinology.

Perspectives for improved and more accurate classification of thyroid epithelial tumors.

R. Paschke, S. Hauptmann, T. Giordano, 2008, The Journal of clinical endocrinology and metabolism.

Comparison of Color Flow Doppler Sonography (CFDS) and immunohistologic detection of microvessels for the assessment of the malignancy of thyroid nodules.

R. Paschke, M. Eszlinger, R. Gärtner, 2010, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Evaluation of peroxisome proliferator-activated receptor-gamma expression in benign and malignant thyroid pathologies.

R. Paschke, M. Eszlinger, A. Tannapfel, 2005, Thyroid : official journal of the American Thyroid Association.

Human transmissible spongiform encephalopathies.

R. Paschke, S. Dave, F. Lammert, 1998, Releve epidemiologique hebdomadaire.

Cytology and mRNA expression analysis of fine needle aspirates of thyroid nodules in an East German region with borderline iodine deficiency.

M. Eszlinger, A. Tönjes, A. Tannapfel, 2006, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Inverse correlation of miRNA and cell cycle-associated genes suggests influence of miRNA on benign thyroid nodule tumorigenesis.

R. Paschke, S. Bornstein, M. Eszlinger, 2013, The Journal of clinical endocrinology and metabolism.

Evidence for a more pronounced effect of genetic predisposition than environmental factors on goitrogenesis by a case control study in an area with low normal iodine supply.

R. Paschke, M. Eszlinger, J. Singer, 2011, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Late Manifestation of Subclinical Hyperthyroidism After Goitrogenesis in an Index Patient with a N670S TSH Receptor Germline Mutation Masquerading as TSH Receptor Antibody Negative Graves’ Disease

R. Paschke, M. Eszlinger, S. Paschke, 2012, Hormone and Metabolic Research.

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany

Kerstin Dietrich, Joachim Thiery, Andrew P Morris, 2010, European Journal of Human Genetics.

Ruling in or ruling out thyroid malignancy by molecular diagnostics of thyroid nodules.

R. Paschke, L. Hegedüs, M. Eszlinger, 2014, Best practice & research. Clinical endocrinology & metabolism.

TFF3-based candidate gene discrimination of benign and malignant thyroid tumors in a region with borderline iodine deficiency.

M. Eszlinger, K. Krause, D. Fuhrer, 2008, The Journal of clinical endocrinology and metabolism.

Evaluation of insulin-like growth factor II, cyclooxygenase-2, ets-1 and thyroid-specific thyroglobulin mRNA expression in benign and malignant thyroid tumours.

R. Paschke, D. Hasenclever, M. Eszlinger, 2005, European Journal of Endocrinology.

Gene expression analysis reveals evidence for inactivation of the TGF-β signaling cascade in autonomously functioning thyroid nodules

R. Paschke, S. Kropf, M. Eszlinger, 2004, Oncogene.

Laser capture microdissection is a valuable tool in the preoperative molecular screening of follicular lesions of the thyroid: an institutional experience

R. Paschke, L. Mazzucchelli, M. Eszlinger, 2015, Cytopathology : official journal of the British Society for Clinical Cytology.

Two-miRNA classifiers differentiate mutation-negative follicular thyroid carcinomas and follicular thyroid adenomas in fine needle aspirations with high specificity

R. Paschke, L. Hegedüs, S. Hauptmann, 2016, Endocrine.

Malignancy is in the eye of the beholder: Pathologic diagnosis of challenging follicular neoplasms in the era of noninvasive follicular thyroid neoplasms with papillary-like nuclear features and immunohistochemical and molecular adjuncts.

Moosa Khalil, M. Eszlinger, J. Pasieka, 2020, Surgery.

The Thyroid Stimulating Hormone Receptor Mutation Database Update.

R. Paschke, M. Eszlinger, Lorraine Lau, 2020, Thyroid : official journal of the American Thyroid Association.

The Leipzig Thyrotropin Receptor Mutation Database: Update 2012

R. Paschke, M. Eszlinger, I. Nébel, 2012, European Thyroid Journal.

Cases of borderline in vitro constitutive thyrotropin receptor activity: how to decide whether a thyrotropin receptor mutation is constitutively active or not?

R. Paschke, M. Eszlinger, K. Krohn, 2009, Thyroid : official journal of the American Thyroid Association.

miRNAs with the Potential to Distinguish Follicular Thyroid Carcinomas from Benign Follicular Thyroid Tumors: Results of a Meta-analysis

R. Paschke, M. Eszlinger, B. Wojtaś, 2014, Hormone and Metabolic Research.

Clinical value of molecular markers as diagnostic and prognostic tools to guide treatment of thyroid cancer

R. Paschke, M. Eszlinger, P. Valderrabano, 2023, Clinical endocrinology.

Sialylation of Human Thyrotropin Receptor Improves and Prolongs Its Cell-Surface Expression

R. Paschke, M. Eszlinger, K. Krohn, 2005, Molecular Pharmacology.

Sialylation of human thyrotropin receptor improves and prolongs its cell-surface expression.

R. Paschke, M. Eszlinger, K. Krohn, 2005, Molecular pharmacology.

Evaluation of a Two-Year Routine Application of Molecular Testing of Thyroid Fine-Needle Aspirations Using a Seven-Gene Panel in a Primary Referral Setting in Germany.

R. Paschke, C. Franzius, M. Eszlinger, 2017, Thyroid.

Histology‐based molecular profiling improves mutation detection for advanced thyroid cancer

R. Paschke, Moosa Khalil, Helen J. Huang, 2021, Genes, chromosomes & cancer.

Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas

R. Paschke, S. Hauptmann, M. Eszlinger, 2014, Molecular and Cellular Endocrinology.

Impact of Different Methodologies on the Detection of Point Mutations in Routine Air-dried Fine Needle Aspiration (FNA) Smears

R. Paschke, L. Hegedüs, M. Eszlinger, 2013, Hormone and Metabolic Research.

Comparison of differential gene expression of hot and cold thyroid nodules with primary epithelial cell culture models by investigation of co-regulated gene sets.

R. Paschke, J. Läuter, M. Eszlinger, 2006, Biochimica et biophysica acta.

Increased power of microarray analysis by use of an algorithm based on a multivariate procedure

E. Schuster, Kenneth A. Krohn, M. Eszlinger, 2005, Bioinform..

Growth factor expression in cold and hot thyroid nodules.

R. Paschke, M. Eszlinger, K. Krohn, 2001, Thyroid : official journal of the American Thyroid Association.

Hereditary fructose intolerance

Jeroen J. Bax, R. Paschke, S. Dave, 2020, Definitions.

Evaluation of a Two-Year Routine Application of Molecular Testing of Thyroid Fine-Needle Aspirations Using a Seven-Gene Panel in a Primary Referral Setting in Germany.

R. Paschke, C. Franzius, M. Eszlinger, 2017, Thyroid : official journal of the American Thyroid Association.

Feinnadelzytologie von Schilddrüsenknoten: Molekulare Diagnostik in der klinischen Routine

R. Paschke, C. Franzius, M. Eszlinger, 2014, Deutsche Medizinische Wochenschrift.

Prospective Validation of ThyroSPEC Molecular Testing of Indeterminate Thyroid Nodule Cytology Following Diagnostic Pathway Optimization.

Moosa Khalil, M. Eszlinger, Zoya Punjwani, 2023, Thyroid : official journal of the American Thyroid Association.

Hermansky-Pudlak syndrome.

H. Scharnagl, J. Bax, M. Eszlinger, 2001, European journal of dermatology : EJD.