Paul L Huang

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Targeted disruption of the neuronal nitric oxide synthase gene

S. Snyder, D. Bredt, M. Fishman, 1993, Cell.

Rapid Cerebral Ischemic Preconditioning in Mice Deficient in Endothelial and Neuronal Nitric Oxide Synthases

I. T. Demchenko, M. Moskowitz, D. Atochin, 2003, Stroke.

Deletion of exon 6 of the neuronal nitric oxide synthase gene in mice results in hypogonadism and infertility.

Paul L Huang, R. Gyurko, S. Leupen, 2002, Endocrinology.

Through-skull fluorescence imaging of the brain in a new near-infrared window

Shuo Diao, Junlei Chang, Guosong Hong, 2014, Nature Photonics.

Near-Infrared Fluorescent Imaging of Matrix Metalloproteinase Activity After Myocardial Infarction

Jiqiu Chen, Ralph Weissleder, R. Weissleder, 2005, Circulation.

Optical coherence tomography for the quantitative study of cerebrovascular physiology

David A Boas, Scott Barry, Harsha Radhakrishnan, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase

Eric R Kandel, Michael Kiebler, E. Kandel, 1996, Cell.

Implantable magnetic relaxation sensors measure cumulative exposure to cardiac biomarkers

M. Cima, Yibo Ling, Paul L Huang, 2011, Nature Biotechnology.

Hyperlipidemia Disrupts Cerebrovascular Reflexes and Worsens Ischemic Perfusion Defect

Satoshi Kashiwagi, Cenk Ayata, C. Ayata, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

overloaded plantaris muscle upregulation of contractile protein mRNA in In vivo inhibition of nitric oxide synthase impairs

Paul L Huang, K. Deruisseau, J. Percival, 2015 .

In Vivo Imaging of Proteolytic Activity in Atherosclerosis

Vasilis Ntziachristos, Jiqiu Chen, Ralph Weissleder, 2002, Circulation.

Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion

Matthias Endres, Csaba Szabó, Gwen Scott, 1998, Neuroscience Letters.

Endothelial nitric oxide synthase and endothelial dysfunction

Paul L Huang, 2003, Current hypertension reports.

Unraveling the links between diabetes, obesity, and cardiovascular disease.

Paul L Huang, 2005, Circulation research.

Inducible Nitric-oxide Synthase Is an Important Contributor to Prolonged Protective Effects of Ischemic Preconditioning in the Mouse Kidney*

Paul L Huang, K. Park, J. Bonventre, 2003, Journal of Biological Chemistry.

Protective Effects of Statins Involving Both eNOS and tPA in Focal Cerebral Ischemia

M. Moskowitz, E. Lo, S. Amin-Hanjani, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Endothelial Dysfunction Abrogates the Efficacy of Normobaric Hyperoxia in Stroke

C. Ayata, D. Atochin, J. Kim, 2014, The Journal of Neuroscience.

Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice.

C. Kahn, M. Rekhter, G. King, 2010, Cell metabolism.

Induction of Vascular Insulin Resistance and Endothelin-1 Expression and Acceleration of Atherosclerosis by the Overexpression of Protein Kinase C-&bgr; Isoform in the Endothelium

G. King, Paul L Huang, Qian Li, 2013, Circulation research.

Physiological stress increases renal injury in eNOS-knockout mice

J. Loscalzo, Paul L Huang, Mildred A. Pointer, 2012, Hypertension Research.

Cerebral Blood Volume Affects Blood–Brain Barrier Integrity in an Acute Transient Stroke Model

Y. R. Kim, D. Atochin, J. K. Kim, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Rho-Kinase Inhibition Improves Ischemic Perfusion Deficit in Hyperlipidemic Mice

C. Ayata, Paul L Huang, H. Shin, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Oleuropein and Related Compounds from Olive Plants Modulate Adipogenesis

S. Lee-Huang, Paul L Huang, Jae Wook Lee, 2013 .

HDAC5: going with the flow.

Paul L Huang, 2010, Blood.

Inhibition of Marfan Syndrome Aortic Root Dilation by Losartan: Role of Angiotensin II Receptor Type 1-Independent Activation of Endothelial Function.

Paul L Huang, Mitra Esfandiarei, J. Hogg, 2018, The American journal of pathology.

Endothelial Nitric Oxide Synthase Knockdown in Human Stem Cells Impacts Mitochondrial Biogenesis and Adipogenesis: Live-Cell Real-Time Fluorescence Imaging

S. Lee-Huang, Paul L Huang, P. Huang, 2021, Journal of clinical medicine.

Endothelial Nitric Oxide Synthase Limits Left Ventricular Remodeling After Myocardial Infarction in Mice

Richard T. Lee, M. Lindsey, Paul L Huang, 2001, Circulation.

Insulin decreases atherosclerosis by inducing endothelin receptor B expression.

G. King, Paul L Huang, Qian Li, 2016, JCI insight.

Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2

Paul L Huang, W. Sessa, M. Schleicher, 2011, Proceedings of the National Academy of Sciences.

Anti-Inflammatory Effect of Targeted Delivery of SOD to Endothelium: Mechanism, Synergism with NO Donors and Protective Effects In Vitro and In Vivo

D. Atochin, Paul L Huang, V. Muzykantov, 2013, PloS one.

Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms.

Joao A. C. Lima, B. O’Rourke, Paul L Huang, 2002 .

Oral nitrite restores age-dependent phenotypes in eNOS-null mice.

D. Atochin, Paul L Huang, J. Baur, 2018, JCI insight.

The role of endothelial nitric oxide synthase (eNOS) in endothelial activation: insights from eNOS-knockout endothelial cells

R. Gerszten, Paul L Huang, W. Sessa, 2004 .

Role of endothelial nitric oxide synthase in endothelial activation: insights from eNOS knockout endothelial cells.

R. Gerszten, Paul L Huang, W. Sessa, 2004, American journal of physiology. Cell physiology.

eNOS phosphorylation on serine 1176 affects insulin sensitivity and adiposity.

D. Atochin, Paul L Huang, W. Sessa, 2013, Biochemical and biophysical research communications.

Tissue Plasminogen Activator Promotes Matrix Metalloproteinase-9 Upregulation After Focal Cerebral Ischemia

D. Atochin, K. Arai, E. Lo, 2005, Stroke.

Near-infrared fluorescent imaging of matrix metalloproteinase activity following myocardial infarction

C. Tung, Paul L Huang, J. Allport, 2013 .

Nitric oxide synthase 3 deficiency limits adverse ventricular remodeling after pressure overload in insulin resistance.

D. Atochin, Paul L Huang, M. Scherrer-Crosbie, 2011, American journal of physiology. Heart and circulatory physiology.

Near‐infrared II photobiomodulation augments nitric oxide bioavailability via phosphorylation of endothelial nitric oxide synthase

D. Atochin, Paul L Huang, S. Feil, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A new class of anti‐HIV agents: GAP31, DAPs 30 and 32

S. Lee-Huang, Paul L Huang, H. Kung, 1991, FEBS letters.

Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: part II. integrase inhibition.

S. Lee-Huang, Paul L Huang, Jae Wook Lee, 2007, Biochemical and biophysical research communications.

Rho-Kinase Inhibition Acutely Augments Blood Flow in Focal Cerebral Ischemia via Endothelial Mechanisms

M. Moskowitz, C. Ayata, D. Boas, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Mice Lacking Inducible Nitric Oxide Synthase Demonstrate Impaired Killing of Porphyromonas gingivalis

Paul L Huang, R. Gyurko, A. Kantarcı, 2003, Infection and Immunity.

Effects of Neuroglobin Overexpression on Acute Brain Injury and Long-Term Outcomes After Focal Cerebral Ischemia

D. Atochin, E. Lo, Paul L Huang, 2008, Stroke.

Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability

R K Jain, R. Jain, D. Buerk, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Plant Proteins with Antiviral Activity Against Human Immunodeficiency Virus

S. Lee-Huang, Paul L Huang, H. Kung, 1992 .

Oxidative stress and compartment of gene expression determine proatherosclerotic effects of inducible nitric oxide synthase.

Paul L Huang, B. Nieswandt, G. Ertl, 2009, The American journal of pathology.

airway responsiveness to histamine in guinea pigs Nitric oxide derived from sympathetic nerves regulates

J. Boutin, Paul L Huang, F. Cogé, 2013 .

Accelerated Atherosclerosis, Aortic Aneurysm Formation, and Ischemic Heart Disease in Apolipoprotein E/Endothelial Nitric Oxide Synthase Double-Knockout Mice

Paul L Huang, M. Picard, M. Scherrer-Crosbie, 2001, Circulation.

Nitric Oxide Inhibits (cid:97) 2 -Adrenoceptor–Mediated Endothelium-Dependent Vasodilation

M. Fishman, J. Bevan, Paul L Huang, 1998 .

Oleuropein and Related Compounds Reduce Atherosclerosis

S. Lee-Huang, Paul L Huang, P. Huang, 2010 .

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

M. Moskowitz, M. Fishman, H. Mashimo, 1995, Nature.

Increased eNOS accounts for changes in connexin expression in renal arterioles during diabetes.

Paul L Huang, C. Hill, S. Kawashima, 2006, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.

Maternal Aggression in Endothelial Nitric Oxide Synthase-Deficient Mice

R. Nelson, Paul L Huang, S. Gammie, 2000, Hormones and Behavior.

muscular dystrophy The role of free radicals in the pathophysiology of

Robert W. Taylor, F. Muntoni, Paul L Huang, 2015 .

Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms

Joao A. C. Lima, B. O’Rourke, Paul L Huang, 2002, Nature.

Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

D. Roberts, Paul L Huang, K. Chien, 2009, Nature.

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

Paul L Huang, S. Bhushan, J. Calvert, 2014, Proceedings of the National Academy of Sciences.

Contribution of Nitric Oxide Synthases 1, 2, and 3 to Airway Hyperresponsiveness and Inflammation in a Murine Model of Asthma

J. Drazen, C. Yandava, Paul L Huang, 1999, The Journal of experimental medicine.

Photobiomodulation and nitric oxide signaling.

D. Atochin, Paul L Huang, S. Kashiwagi, 2022, Nitric oxide : biology and chemistry.

eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases

Paul L Huang, W. Sessa, M. Schleicher, 2014, Journal of Cell Science.

Macula Densa Nitric Oxide Synthase 1β Protects against Salt-Sensitive Hypertension.

L. Juncos, Paul L Huang, J. Pollock, 2016, Journal of the American Society of Nephrology : JASN.

Cerebrovascular Thromboprophylaxis in Mice by Erythrocyte-Coupled Tissue-Type Plasminogen Activator

D. Atochin, S. Kasner, Paul L Huang, 2008, Circulation.

Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition

S. Lee-Huang, Paul L Huang, Jae Wook Lee, 2007, Biochemical and Biophysical Research Communications.

Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition

S. Lee-Huang, Paul L Huang, Jae Wook Lee, 2007, Biochemical and Biophysical Research Communications.

Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43

M. Fishman, S. Strittmatter, H. Mashimo, 1995, Cell.

MAP 30: a new inhibitor of HIV‐1 infection and replication

S. Lee-Huang, Paul L Huang, H. Kung, 1990, FEBS letters.

Isoflurane‐induced Cerebral Hyperemia in Neuronal Nitric Oxide Synthase Gene Deficient Mice

M. Moskowitz, C. Ayata, A. Hudetz, 1997, Anesthesiology.

Structural and functional modeling of human lysozyme reveals a unique nonapeptide, HL9, with anti-HIV activity.

V. Maiorov, N. Kallenbach, S. Lee-Huang, 2005, Biochemistry.

Nitric oxide and cerebral ischemic preconditioning.

Paul L Huang, 2004, Cell calcium.

Leukocyte-endothelial cell interactions in nitric oxide synthase-deficient mice.

Steven P Jones, Paul L Huang, D. Lefer, 1999, American journal of physiology. Heart and circulatory physiology.

Aldosterone Regulates Vascular Gene Transcription via Oxidative Stress–Dependent and –Independent Pathways

L. Iyer, Paul L Huang, M. Mendelsohn, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase

S. Snyder, M. Fishman, R. Nelson, 1995, Nature.

Acetylcholine‐induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice

M. Fishman, Paul L Huang, P. Vanhoutte, 1999, British journal of pharmacology.

Lack of Endothelial Nitric Oxide Synthase Aggravates Murine Pneumococcal Meningitis

Paul L Huang, H. Pfister, F. Winkler, 2001, Journal of neuropathology and experimental neurology.

eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases

Paul L Huang, W. Sessa, M. Schleicher, 2013, Journal of Cell Science.

Endothelial nitric oxide synthase transgenic models of endothelial dysfunction

D. Atochin, Paul L Huang, 2010, Pflügers Archiv - European Journal of Physiology.

Enlarged Infarcts in Endothelial Nitric Oxide Synthase Knockout Mice are Attenuated by Nitro-L-Arginine

M. Moskowitz, C. Ayata, M. Fishman, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Nitric oxide is proangiogenic in the retina and choroid *

P. Campochiaro, M. Fishman, Paul L Huang, 2002, Journal of cellular physiology.

Noxious Stimulation-induced Neuroplasticity Is Not Altered in Transgenic Mice Deficient in Neuronal Nitric Oxide Synthase

K. Abe, Paul L Huang, C. Root, 1994 .

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

James M. Harris, L. Zon, C. Ceol, 2009, Cell.

Reduced Brain Edema and Infarction Volume in Mice Lacking the Neuronal Isoform of Nitric Oxide Synthase after Transient MCA Occlusion

M. Moskowitz, M. Fishman, Paul L Huang, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cardiovascular roles of nitric oxide: a review of insights from nitric oxide synthase gene disrupted mice.

Paul L Huang, Victor W T Liu, 2007, Cardiovascular research.

Noncholinergic penile erection in mice lacking the gene for endothelial nitric oxide synthase.

Paul L Huang, A. Burnett, J. K. Crone, 2002, Journal of andrology.

Endothelial Nitric Oxide Synthase Regulates Microlymphatic Flow via Collecting Lymphatics

R. Jain, D. Fukumura, Paul L Huang, 2004, Circulation research.

Case records of the Massachusetts General Hospital. Case 11-2014. A man with traumatic injuries after a bomb explosion at the Boston Marathon.

S. Fagan, S. Abbara, G. Velmahos, 2014, The New England journal of medicine.

Deficient eNOS Phosphorylation Is a Mechanism for Diabetic Vascular Dysfunction Contributing to Increased Stroke Size

Emiri T. Mandeville, D. Atochin, E. Lo, 2013, Stroke.

eNOS Protects from Atherosclerosis Despite Relevant Superoxide Production by the Enzyme in apoE−/− Mice

Paul L Huang, B. Nieswandt, G. Ertl, 2012, PloS one.

eNOS, metabolic syndrome and cardiovascular disease

Paul L Huang, 2009, Trends in Endocrinology & Metabolism.

Simvastatin Exerts Both Anti-inflammatory and Cardioprotective Effects in Apolipoprotein E—Deficient Mice

A. M. Lefer, Michaela R. Hoffmeyer, P. Huang, 2001, Circulation.

C-Reactive Protein Causes Insulin Resistance in Mice Through Fcγ Receptor IIB–Mediated Inhibition of Skeletal Muscle Glucose Delivery

D. Atochin, Paul L Huang, C. Mineo, 2013, Diabetes.

C-Reactive Protein Causes Insulin Resistance in Mice Through Fc γ Receptor IIB – Mediated Inhibition of Skeletal Muscle Glucose

D. Atochin, Paul L Huang, W. Vongpatanasin, 2013 .

Localization of NADPH-diaphorase/nitric oxide synthase in the rat retina: an electron microscopic study

M. Fishman, Paul L Huang, G. Wolf, 1995, Brain Research.

Effect of Blood Nitrite and Nitrate Levels on Murine Platelet Function

Alan N. Schechter, A. Schechter, Paul L Huang, 2013, PloS one.

Relationships in Vivo The Akt 1-eNOS Axis Illustrates the Specificity of Kinase-Substrate `

Paul L Huang, W. Sessa, M. Schleicher, 2009 .

Long-Term Treatment With N&ohgr;-Nitro-l-Arginine Methyl Ester Causes Arteriosclerotic Coronary Lesions in Endothelial Nitric Oxide Synthase-Deficient Mice

Y. Sasaguri, Paul L Huang, A. Tanimoto, 2002, Circulation.

Relative contributions of endothelial , inducible , and neuronal NOS to tone in the murine pulmonary circulation

Paul L Huang, K. Morris, D. Rodman, 1999 .

NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels.

R. Jain, D. Buerk, L. Munn, 2005, The Journal of clinical investigation.

Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle.

Paul L Huang, J. Percival, S. Froehner, 2010, The Journal of clinical investigation.

Loss of nNOS inhibits compensatory muscle hypertrophy and exacerbates inflammation and eccentric contraction-induced damage in mdx mice.

Paul L Huang, J. Percival, S. Froehner, 2015, Human molecular genetics.

muscleresponse in contracting fast-twitch skeletal nNOS and eNOS modulate cGMP formation and

Kelvin E. Jones, R. Grange, J. Stull, 2015 .

Nitric Oxide Protects Cardiac Sarcolemmal Membrane Enzyme Function and Ion Active Transport against Ischemia-induced Inactivation*

L. Becker, Paul L Huang, T. Dawson, 2003, Journal of Biological Chemistry.

Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle.

D. Kass, L. Becker, Paul L Huang, 2002, Biochemical and biophysical research communications.

Expression of neuronal nitric oxide synthase splice variants in atherosclerotic plaques of apoE knockout mice.

A. Marx, Paul L Huang, G. Ertl, 2009, Atherosclerosis.

Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects.

C. Piantadosi, D. Gutsaeva, B. Allen, 2008, American journal of physiology. Lung cellular and molecular physiology.

Atheroprotective Effects of Neuronal Nitric Oxide Synthase in Apolipoprotein E Knockout Mice

A. Marx, Paul L Huang, G. Ertl, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Alternatively spliced neuronal nitric oxide synthase mediates penile erection.

S. Snyder, A. Sawa, Paul L Huang, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Genetic Disruption of Nitric Oxide Synthases and Cardiovascular Disease: Lessons from a Candidate Gene

Paul L Huang, 2004 .

Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases

C. Piantadosi, D. Atochin, J. Astern, 2003, Neuroscience Letters.

Vasculoprotective Roles of Neuronal Nitric Oxide Synthase

Y. Sasaguri, Paul L Huang, H. Shimokawa, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Differential expression of alternatively spliced isoforms of neuronal nitric oxide synthase (nNOS) and N-methyl-D-aspartate receptors (NMDAR) in knockout mice deficient in nNOS alpha (nNOS alpha(Delta/Delta) mice).

Paul L Huang, B. Seidel, G. Wolf, 2000, Brain research. Molecular brain research.

Myocardial reperfusion injury in neuronal nitric oxide synthase deficient mice

Paul L Huang, D. Lefer, W. G. Girod, 2000, Coronary artery disease.

Vascular Factors Are Critical in Selective Neuronal Loss in an Animal Model of Impaired Oxidative Metabolism

Paul L Huang, G. Gibson, N. Calingasan, 2000, Journal of neuropathology and experimental neurology.

Stroke and Nitric Oxide

Paul L Huang, N. Stagliano, 2000 .

Use of Mutant Mice to Elucidate Neuroprotective and Neurotoxic Actions of Nitric Oxide in Cerebral Ischemia

M. Moskowitz, Paul L Huang, T. Dalkara, 2000 .

The Cerebral Metabolic Consequences of Nitric Oxide Synthase Deficiency: Glucose Utilization in Endothelial and Neuronal Nitric Oxide Synthase Null Mice

M. Moskowitz, C. Ayata, M. Beal, 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Expression of Hypothalamic Peptides in Mice Lacking Neuronal Nitric Oxide Synthase: Reduced β-END Immunoreactivity in the Arcuate Nucleus

B. Bogerts, M. Fishman, Paul L Huang, 1998, Neuroendocrinology.

Resistance of neuronal nitric oxide synthase-deficient mice to cocaine-induced locomotor sensitization

Paul L Huang, Syed F. Ali, Y. Itzhak, 1998, Psychopharmacology.

Disruption of the endothelial nitric oxide synthase gene: Effect on vascular response to injury

Paul L Huang, 1998 .

Attenuated Neurotransmitter Release and Spreading Depression-Like Depolarizations after Focal Ischemia in Mutant Mice with Disrupted Type I Nitric Oxide Synthase Gene

M. Moskowitz, E. Lo, Paul L Huang, 1998, The Journal of Neuroscience.

Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase

N. Prabhakar, Paul L Huang, D. Kline, 1998, The Journal of physiology.

Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice.

M. Moskowitz, C. Ayata, Paul L Huang, 1998, American journal of physiology. Heart and circulatory physiology.

Ontogeny and Regulation of Hypothalamic Neurons

B. Bogerts, M. Fishman, Paul L Huang, 1998 .

MPP+Induced Substantia Nigra Degeneration Is Attenuated in nNOS Knockout Mice

B. Hyman, M. Fishman, M. Beal, 1997, Neurobiology of Disease.

Alteration of protein kinase C activity after transient focal cerebral ischemia in mice using in vitro [3H]phorbol-12,13-dibutyrate binding autoradiography

M. Moskowitz, Paul L Huang, G. Ayata, 1997, Brain Research.

Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice.

J. Drazen, C. Yandava, Paul L Huang, 1997, American journal of physiology. Lung cellular and molecular physiology.

Mechanisms of Reduced Striatal NMDA Excitotoxicity in Type I Nitric Oxide Synthase Knock-Out Mice

M. Moskowitz, B. Hyman, C. Ayata, 1997, The Journal of Neuroscience.

Neuronal nitric oxide synthase mutant mice show smaller infarcts and attenuated apparent diffusion coefficient changes in the peri‐infarct zone during focal cerebral ischemia

M. Moskowitz, G. Zaharchuk, M. Fishman, 1997, Magnetic resonance in medicine.

Striatal Malonate Lesions Are Attenuated in Neuronal Nitric Oxide Synthase Knockout Mice

J. Schulz, M. Fishman, M. Beal, 1996, Journal of neurochemistry.

Effects of Targeted Neuronal Nitric Oxide Synthase Gene Disruption and Nitro sup G -L-Arginine Methylester on the Threshold for Isoflurane Anesthesia

Paul L Huang, W. Zapol, F. Ichinose, 1995, Anesthesiology.

Effects of Nitric Oxide on Atherosclerosis

Paul L Huang, T. Pong, 2015 .

Phosphomimetic Modulation of eNOS Improves Myocardial Reperfusion and Mimics Cardiac Postconditioning in Mice

D. Atochin, Paul L Huang, M. Scherrer-Crosbie, 2014, PloS one.

The Akt1-eNOS Axis Illustrates the Specificity of Kinase-Substrate Relationships in Vivo

Paul L Huang, W. Sessa, T. Murata, 2009, Science Signaling.

The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.

M. Moskowitz, C. Ayata, D. Atochin, 2007, The Journal of clinical investigation.

Stimulation of nitric oxide synthase in cerebral cortex due to elevated partial pressures of oxygen: an oxidative stress response.

D. Buerk, Paul L Huang, S. Thom, 2002, Journal of neurobiology.

Role of endothelial nitric oxide in cerebrovascular regulation.

D. Atochin, Paul L Huang, 2011, Current pharmaceutical biotechnology.

Endothelial Nitric Oxide Synthase-Dependent Cerebral Blood Flow Augmentation by L-Arginine After Chronic Statin Treatment

M. Moskowitz, M. Endres, P. Huang, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Somatostatin+/nNOS+ neurons are involved in delta electroencephalogram activity and cortical-dependent recognition memory.

D. Atochin, R. Strecker, J. McKenna, 2019, Sleep.

Effects of Chronic Treatment With l-Arginine on Atherosclerosis in ApoE Knockout and ApoE/Inducible NO Synthase Double-Knockout Mice

J. Astern, Paul L Huang, H. Ichinose, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Gαo is necessary for muscarinic regulation of Ca2+ channels in mouse heart

E. Neer, M. Fishman, H. Mashimo, 1997 .

Focal Ischemic Preconditioning Induces Rapid Tolerance to Middle Cerebral Artery Occlusion in Mice

M. Moskowitz, Paul L Huang, N. Stagliano, 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Dietary Supplements and Cardiovascular Disease: What is the Evidence and What Should We Recommend?

Paul L Huang, S. Kashiwagi, 2012 .

Delayed Paraplegia After Spinal Cord Ischemic Injury Requires Caspase-3 Activation in Mice

D. Atochin, Paul L Huang, M. Kaneki, 2011, Stroke.

Genetic Deficiency of Inducible Nitric Oxide Synthase Reduces Atherosclerosis and Lowers Plasma Lipid Peroxides in Apolipoprotein E–Knockout Mice

J. Astern, Paul L Huang, Jiqiu Chen, 2001, Circulation.

cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice

Jesse D. Roberts, C. Ayata, D. Atochin, 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Hypertension Does Not Account for the Accelerated Atherosclerosis and Development of Aneurysms in Male Apolipoprotein E/Endothelial Nitric Oxide Synthase Double Knockout Mice

Jiqiu Chen, J. Astern, Paul L Huang, 2001, Circulation.

Elimination of Aggressive Behavior in Male Mice Lacking Endothelial Nitric Oxide Synthase

S. Snyder, L. Kriegsfeld, R. Nelson, 1999, The Journal of Neuroscience.

Trastuzumab and lapatinib differ in effects on calcium cycling and HER2 expression in human embryonic stem cell-derived cardiomyocytes

Paul L Huang, Sharon M. Cawley, K. Bloch, 2013 .

Nitric Oxide Mediates 17β-Estradiol-Stimulated Human and Rodent Osteoblast Proliferation and Differentiation

J. Polak, Paul L Huang, F. Afzal, 2000 .

Ejaculatory Abnormalities in Mice Lacking the Gene for Endothelial Nitric Oxide Synthase (eNOS−/−)

L. Kriegsfeld, R. Nelson, Paul L Huang, 1999, Physiology & Behavior.

Normal vascular development in mice deficient in endothelial NO synthase: possible role of neuronal NO synthase.

Paul L Huang, R. Caldwell, A. El-Remessy, 2003, Molecular vision.

Neuronal nitric oxide synthase (NOS) regulates leukocyte‐endothelial cell interactions in endothelial NOS deficient mice

P. Huang, E. Raharjo, P. Kubes, 2001, British journal of pharmacology.

Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice

D. Atochin, Paul L Huang, C. Mineo, 2016, Diabetes.

Decreased arteriolar density in endothelial nitric oxide synthase knockout mice is due to hypertension, not to the constitutive defect in endothelial nitric oxide synthase enzyme

B. Lévy, Paul L Huang, A. Tedgui, 2002, Journal of hypertension.

Renal abnormalities in mutant mice

M. Fishman, H. Mashimo, Paul L Huang, 1996, Nature.

The effect of salt on renal damage in eNOS-deficient mice

J. Loscalzo, Paul L Huang, Mildred A. Pointer, 2010, Hypertension Research.

Diabetes Mellitus and the Metabolic Syndrome

Paul L Huang, 2014 .

A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia–reperfusion injury in mice

D. Atochin, Paul L Huang, A. Khlebnikov, 2016, Neuroscience Letters.

Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.

P. Huang, M. Fishman, J. Isner, 1998, The Journal of clinical investigation.

Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase.

M. Moskowitz, P. Huang, M. Fishman, 1994, Science.

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase.

M. Moskowitz, M. Endres, P. Huang, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Genetic analysis of NOS isoforms using nNOS and eNOS knockout animals.

P. Huang, E. Lo, Paul L Huang, 1998, Progress in brain research.

Mouse models of nitric oxide synthase deficiency.

P. Huang, Paul L Huang, 2000, Journal of the American Society of Nephrology : JASN.

[3H]L-NG-Nitroarginine Binding after Transient Focal Ischemia and NMDA-Induced Excitotoxicity in Type I and Type III Nitric Oxide Synthase Null Mice

M. Moskowitz, C. Ayata, P. Huang, 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS.

E R Kandel, S H Snyder, E. Kandel, 1994, Science.

Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity.

J. Polak, Paul L Huang, F. Afzal, 2001, The American journal of pathology.

Relative contributions of endothelial, inducible, and neuronal NOS to tone in the murine pulmonary circulation.

P. Huang, Paul L Huang, K. Morris, 1999, American journal of physiology. Lung cellular and molecular physiology.

The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia.

P. Huang, Paul L Huang, K. Morris, 1999, The Journal of clinical investigation.

Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3.

P. Huang, Paul L Huang, M. Picard, 1998, The Journal of clinical investigation.

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis

M. Gurney, P. Huang, M. Beal, 1999, Neuroscience.