J. Wroblewski

J. Wroblewski, V. Soldatenkov, A. Surin, 1997, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

Intrinsic GABAergic system of adrenal chromaffin cells.

A. Guidotti, J. Wroblewski, Y. Kataoka, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Neuroprotective effects of the agonist of metabotropic glutamate receptors ABHxD-I in two animal models of cerebral ischaemia.

J. Wroblewski, A. Kozikowski, J. Lazarewicz, 2006, Resuscitation.

Ligand Bias at Metabotropic Glutamate 1a Receptors: Molecular Determinants That Distinguish β-Arrestin-Mediated from G Protein-Mediated Signaling

Eric J Miller, Eric J. Miller, J. Wroblewski, 2012, Molecular Pharmacology.

Sodium nitroprusside inhibits N-methyl-D-aspartate-evoked calcium influx via a nitric oxide- and cGMP-independent mechanism.

E. Costa, L. Kiedrowski, J. Wroblewski, 1992, Molecular pharmacology.

A Real-Time Method for Measuring cAMP Production Modulated by G a i/o -Coupled Metabotropic Glutamate Receptors s

Eric J Miller, J. Wroblewski, B. Wróblewska, 2014 .

Synthesis of urea-based inhibitors as active site probes of glutamate carboxypeptidase II: efficacy as analgesic agents.

J. Neale, J. Wroblewski, F. Nan, 2004, Journal of medicinal chemistry.

Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells

F. Nicoletti, J. Wroblewski, V. Bruno, 1998, Neuroscience.

Modulation of glutamate receptors: molecular mechanisms and functional implications.

J. Wroblewski, W. Danysz, Wojciech Danysz, 1989, Annual review of pharmacology and toxicology.

Nitric Oxide: A Messenger of Cerebellar Granule Cells

E. Costa, L. Kiedrowski, J. Wroblewski, 1991 .

N‐Methyl‐d‐Aspartate‐Sensitive Glutamate Receptors Induce Calcium‐Mediated Arachidonic Acid Release in Primary Cultures of Cerebellar Granule Cells

E. Costa, J. Wroblewski, J. Lazarewicz, 1990, Journal of neurochemistry.

Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity

A. Guidotti, E. Costa, J. Wroblewski, 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes

E. Costa, E. Costa, J. Wroblewski, 1988, Neuropharmacology.

Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids

E. Costa, F. Nicoletti, J. Wroblewski, 1987, Brain Research.

Phencyclidine is a negative allosteric modulator of signal transduction at two subclasses of excitatory amino acid receptors.

E. Costa, F. Nicoletti, J. Wroblewski, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Magnesium Ions Inhibit the Stimulation of Inositol Phospholipid Hydrolysis by Endogenous Excitatory Amino Acids in Primary Cultures of Cerebellar Granule Cells

E. Costa, F. Nicoletti, J. Wroblewski, 1987, Journal of neurochemistry.

Synthesis, molecular modeling, and biology of the 1-benzyl derivative of APDC-AN apparent mGluR6 selective ligand

J. Wroblewski, Shaomeng Wang, A. Kozikowski, 1997 .

Molecular modeling of the interactions of glutamate carboxypeptidase II with its potent NAAG-based inhibitors.

J. Neale, J. Wroblewski, Shaomeng Wang, 2002, Journal of medicinal chemistry.

Synthesis of N1-substituted analogues of (2R,4R)-4-amino-pyrrolidine-2,4-dicarboxylic acid as agonists, partial agonists, and antagonists of group II metabotropic glutamate receptors

J. Wroblewski, A. Kozikowski, E. Grajkowska, 2001 .

NMDA receptor-mediated arachidonic acid release in neurons: role in signal transduction and pathological aspects.

J. Wroblewski, E. Salińska, J. Lazarewicz, 1992, Advances in experimental medicine and biology.

Pertussis toxin inhibits signal transduction at a specific metabolotropic glutamate receptor in primary cultures of cerebellar granule cells

E. Costa, F. Nicoletti, J. Wroblewski, 1988, Neuropharmacology.

Glutamate impairs neuronal calcium extrusion while reducing sodium gradient

E. Costa, L. Kiedrowski, J. Wroblewski, 1994, Neuron.

The Protective Signaling of Metabotropic Glutamate Receptor 1 Is Mediated by Sustained, β-Arrestin-1-dependent ERK Phosphorylation*

J. Wroblewski, Andrew C. Emery, B. Wolfe, 2010, The Journal of Biological Chemistry.

Synthesis and biology of the rigidified glutamate analogue, trans-2-carboxyazetidine-3-acetic acid (t-CAA)

J. Wroblewski, Shaomeng Wang, A. Kozikowski, 1996 .

Classification and Allosteric Modulation of Excitatory Amino Acid Signal Transduction in Brain Slices and Primary Cultures of Cerebellar Neurons

F. Nicoletti, E. Costa, J. Wroblewski, 1988 .

Learning impairment in rats by N-methyl-D-aspartate receptor antagonists

E. Costa, E. Costa, J. Wroblewski, 1988, Neuropharmacology.

Ornithine as a precursor of neurotransmitter glutamate: effect of canaline on ornithine aminotransferase activity and glutamate content in the septum of rat brain

J. Meek, J. Wroblewski, W. D. Blaker, 1985, Brain Research.

Ganglioside GM1 and its semisynthetic lysogangliosides reduce glutamate neurotoxicity by a novel mechanism.

A. Guidotti, E. Costa, L. Kiedrowski, 1993, Advances in experimental medicine and biology.

Synthesis and biological evaluation of two analogues of (S)- α-methyl -3-carboxyphenylalanine

J. Wroblewski, A. Kozikowski, D. Ma, 1998 .

Synthesis and biological activity of cyclic analogues of MPPG and MCPG as metabotropic glutamate receptor antagonists

J. Wroblewski, Hongbin Sun, D. Ma, 1997 .

Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist.

J. Wroblewski, A. Kozikowski, S. Wang, 1998, Journal of medicinal chemistry.

The Role of Metabotropic Glutamate Receptor 1 Dependent Signaling in Glioma Viability

J. Wroblewski, B. Wróblewska, B. Wolfe, 2018, The Journal of Pharmacology and Experimental Therapeutics.

l-Homocysteine Sulfinic Acid and Other Acidic Homocysteine Derivatives Are Potent and Selective Metabotropic Glutamate Receptor Agonists

J. Nadeau, B. Roth, S. Hufeisen, 2003, Journal of Pharmacology and Experimental Therapeutics.

1-amino-APDC, a partial agonist of group II metabotropic glutamate receptors with neuroprotective properties.

J. Wroblewski, A. Kozikowski, S. Pshenichkin, 1999, Bioorganic & medicinal chemistry letters.

NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR

J. Neale, J. Wroblewski, S. Vicini, 2004, Journal of neurochemistry.

Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism

J. Wroblewski, Andrew C. Emery, B. Wolfe, 2015, Neuropharmacology.

Activation of N-methyl-D-aspartate-sensitive glutamate receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells

E. Costa, J. Wroblewski, M. Palmer, 1988, Neuropharmacology.

Antinociceptive effects of N‐acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ‐11, ZJ‐17 and ZJ‐43 in the rat formalin test and in the rat neuropathic pain model

J. Neale, J. Wroblewski, A. Kozikowski, 2004, The European journal of neuroscience.

Design of remarkably simple, yet potent urea-based inhibitors of glutamate carboxypeptidase II (NAALADase).

J. Neale, J. Wroblewski, A. Kozikowski, 2001, Journal of medicinal chemistry.

Stimulation of phosphoinositide hydrolysis by ibotenic acid in cerebellar neurons via two glutamate receptor subtypes

J. Wroblewski, R. Raulli, 1991 .

N-methyl-d-aspartate receptor-induced translocation of protein kinase C to the nucleus in rat cerebellar slices

J. Wroblewski, R. Raulli, H. Alho, 1994, Neurochemistry International.

Acute and long-term inhibition of agonist-stimulated phosphoinositide hydrolysis by pulse treatment of cerebellar granule cells with TPA.

J. Wroblewski, R. Paulsen, D. Grayson, 1994, Molecular and chemical neuropathology.

alpha-substituted quisqualic acid analogs: new metabotropic glutamate receptor group II selective antagonists.

J. Wroblewski, M. Varasi, A. Kozikowski, 1998, Bioorganic & medicinal chemistry letters.

Metabotropic Glutamate Receptor 1 acts as a Dependence Receptor Creating a Requirement for Glutamate to Sustain the Viability and Growth of Human Melanomas

J. Wroblewski, C. Albanese, Olga C. Rodriguez, 2014, Oncogene.

Two newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor.

J. Wroblewski, T. Gelb, S. Pshenichkin, 2013, Gene.

N‐Acetylaspartylglutamate Selectively Activates mGluR3 Receptors in Transfected Cells

J. Neale, J. Wroblewski, A. Surin, 1997, Journal of neurochemistry.

Temporal and Depolarization‐Induced Changes in the Absolute Amounts of mRNAs Encoding Metabotropic Glutamate Receptors in Cerebellar Granule Neurons In Vitro

M. Santi, J. Wroblewski, D. Grayson, 1994, Journal of neurochemistry.

A Real-Time Method for Measuring cAMP Production Modulated by Gαi/o-Coupled Metabotropic Glutamate Receptors

Eric J. Miller, J. Wroblewski, D. Liotta, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Glycine and d-serine act as positive modulators of signal transduction at N-methyl-d-aspartate sensitive glutamate receptors in cultured cerebellar granule cells

E. Costa, J. Wroblewski, E. Fadda, 1989, Neuropharmacology.

Pretreatment of Cerebellar Granule Cells with Concanavalin A Potentiates Quisqualate‐Stimulated Phosphoinositide Hydrolysis

J. Wroblewski, W. Danysz, R. Raulli, 1991, Journal of neurochemistry.

Inhibition of glutamate-induced cell death by sodium nitroprusside is not mediated by nitric oxide

E. Costa, L. Kiedrowski, J. Wroblewski, 1991, Neuropharmacology.

N‐Acetylaspartylglutamate Inhibits Forskolin‐Stimulated Cyclic AMP Levels via a Metabotropic Glutamate Receptor in Cultured Cerebellar Granule Cells

J. Neale, J. Wroblewski, B. Wróblewska, 1993, Journal of neurochemistry.

Impairment of learning behavior in rats by nmda receptor antagonists radial maze and passive avoidance tests

E. Costa, J. Wroblewski, W. Danysz, 1988 .

[3H]D-serine labels strychnine-insensitive glycine recognition sites of rat central nervous system.

E. Costa, J. Wroblewski, W. Danysz, 1990, Life sciences.

Different coupling of excitatory amino acid receptors with Ca2+ channels in primary cultures of cerebellar granule cells

E. Costa, F. Nicoletti, J. Wroblewski, 1985, Neuropharmacology.

The Envelope Glycoprotein of HIV‐1 Alters NMDA Receptor Function

J. Wroblewski, J. Ferkany, E. Karbon, 1993, The European journal of neuroscience.

Kynurenate and 2-amino-5-phosphonovalerate interact with multiple binding sites of the N-methyl-d-aspartate-sensitive glutamate receptor domain

E. Costa, J. Wroblewski, W. Danysz, 1989, Neuroscience Letters.

The Role of Metabotropic Glutamate Receptor 1 Dependent Signaling in Glioma Viability

J. Wroblewski, B. Wróblewska, B. Wolfe, 2018, Journal of Pharmacology and Experimental Therapeutics.

Profile of phosphatidylinositol metabolism stimulated by carbachol and glutamate in primary cultures of rat cerebellar neurons

E. Costa, J. Wroblewski, S. Hynie, 1989, Neuropharmacology.

Serine-O-phosphate, an endogenous metabolite, inhibits the stimulation of inositol phospholipid hydrolysis elicited by ibotenic acid in rat hippocampal slices

E. Costa, M. Iadarola, F. Nicoletti, 1986, Neuropharmacology.

Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors

J. Wroblewski, D. Liotta, B. Wróblewska, 2015, Molecular Pharmacology.

Pharmacological modulation of gabaergic transmission in cultured cerebellar neurons

E. Costa, J. Wroblewski, S. Vicini, 1986, Neuropharmacology.

Different modes of action of 3-amino-1-hydroxy-2-pyrrolidone (HA-966) and 7-chlorokynurenic acid in the modulation of N-methyl-D-aspartate-sensitive glutamate receptors.

E. Costa, J. Wroblewski, W. Danysz, 1989, Molecular Pharmacology.

Dual function glutamate-related ligands: discovery of a novel, potent inhibitor of glutamate carboxypeptidase II possessing mGluR3 agonist activity.

J. Neale, J. Wroblewski, A. Kozikowski, 2000, Journal of Medicinal Chemistry.

Metabotropic glutamate receptors: From the workbench to the bedside

G. Collingridge, J. Bockaert, J. Wroblewski, 2011, Neuropharmacology.

Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids

J. Wroblewski, E. Fadda, C. Eva, 1987, Brain Research.

l‐Homocysteine Sulfinic Acid and l‐Homocysteic Acid Stimulate Phosphoinositide Hydrolysis in Rat Cortical Neurons

Bryan L. Roth, S. Hufeisen, J. Wroblewski, 2003, Annals of the New York Academy of Sciences.

Synthesis and bioactivity of a new class of rigid glutamate analogues. Modulators of the N-methyl-D-aspartate receptor.

J. Wroblewski, A. Kozikowski, I. Reynolds, 1990, Journal of medicinal chemistry.