D. Mansuy

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Formation of nitrogen oxides and citrulline upon oxidation of N omega-hydroxy-L-arginine by hemeproteins.

J. Boucher, A. Genet, S. Vadon, 1992, Biochemical and biophysical research communications.

Unusual regioselectivity and active site topology of human cytochrome P450 2J2.

D. Mansuy, D. Zeldin, P. Lafite, 2007, Biochemistry.

Metabolic stability of superoxide adducts derived from newly developed cyclic nitrone spin traps.

J. Boucher, D. Mansuy, N. Beziere, 2014, Free radical biology & medicine.

Oxidative decarboxylation of tris-(p-carboxyltetrathiaaryl)methyl radical EPR probes by peroxidases and related hemeproteins: intermediate formation and characterization of the corresponding cations.

J. Boucher, D. Mansuy, C. Decroos, 2010, Archives of biochemistry and biophysics.

Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding.

C David Stout, Eric F. Johnson, D. Mansuy, 2003, Biochemistry.

Hydroxylation of alkanes by hydrogen peroxide: and efficient system using manganese porphyrins and imidazole as catalysts

D. Mansuy, J. Renaud, P. Battioni, 1986 .

Oxidation of alkanes by dioxygen catalysed by photoactivated iron porphyrins

D. Mansuy, A. Maldotti, C. Bartocci, 1991 .

Remarkable ability of horse spleen apoferritin to demetallate hemin and to metallate protoporphyrin IX as a function of pH.

D. Mansuy, J. Mahy, B. Gallois, 1997, Biochemistry.

Interaction between the reductase Tah18 and highly conserved Fe‐S containing Dre2 C‐terminus is essential for yeast viability

D. Mansuy, S. Miron, B. D'Autréaux, 2011, Molecular microbiology.

Bioactivation of clopidogrel and prasugrel: factors determining the stereochemistry of the thiol metabolite double bond.

D. Mansuy, P. Dansette, Assia Hessani, 2015, Chemical research in toxicology.

Thiolactone sulfoxides as new reactive metabolites acting as bis-electrophiles: implication in clopidogrel and prasugrel bioactivation.

D. Mansuy, G. Bertho, P. Dansette, 2013, Chemical research in toxicology.

Cytochromes P450 catalyze both steps of the major pathway of clopidogrel bioactivation, whereas paraoxonase catalyzes the formation of a minor thiol metabolite isomer.

D. Mansuy, G. Bertho, P. Dansette, 2012, Chemical research in toxicology.

Isolation of an iron-nitrene complex from the dioxygen- and iron porphyrin-dependent oxidation of a hydrazine

D. Mansuy, J. Mahy, P. Battioni, 1982 .

Self-induction by triacetyloleandomycin of its own transformation into a metabolite forming a stable 456 nm-absorbing complex with cytochrome P-450.

D. Pessayre, D. Mansuy, V. Descatoire, 1981, Biochemical pharmacology.

Cytochromes P450 and flavin monooxygenases--targets and sources of nitric oxide.

J. Boucher, D. Mansuy, J. S. Kang, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Optimization of yeast-expressed human liver cytochrome P450 3A4 catalytic activities by coexpressing NADPH-cytochrome P450 reductase and cytochrome b5.

D. Mansuy, J. Renaud, D. Pompon, 1992, European journal of biochemistry.

Thermodynamic studies of substrate binding and spin transitions in human cytochrome P-450 3A4 expressed in yeast microsomes.

D. Mansuy, J. Renaud, G. Hui Bon Hoa, 1996, The Biochemical journal.

Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies.

M. Loriot, P. Beaune, J. Boucher, 2015, Biochimica et biophysica acta.

Ferrocenyl quinone methides as strong antiproliferative agents: formation by metabolic and chemical oxidation of ferrocenyl phenols.

D. Mansuy, A. Vessières, G. Jaouen, 2009, Angewandte Chemie.

Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.

Eric F. Johnson, D. Mansuy, M. Sari, 2004, Biochemistry.

Spectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands.

J. Boucher, D. Mansuy, N. Pietrancosta, 2017, Biochimica et biophysica acta. General subjects.

Structural, electrochemical, and spectroscopic properties of a class of dodecasubstituted iron porphyrins bearing four positive charges close to the metal

D. Mansuy, A. Héroux, M. Renner, 2007 .

Metabolism of ellipticine and derivatives and its involvement in the antitumor action of these drugs

D. Mansuy, C. Paoletti, P. Lesca, 1978 .

Spectroscopic, catalytic and binding properties of Bacillus subtilis NO synthase-like protein: comparison with other bacterial and mammalian NO synthases.

J. Boucher, D. Mansuy, D. Stuehr, 2012, Journal of inorganic biochemistry.

Analogies and surprising differences between recombinant nitric oxide synthase-like proteins from Staphylococcus aureus and Bacillus anthracis in their interactions with l-arginine analogs and iron ligands.

J. Boucher, D. Mansuy, I. Mikula, 2006, Journal of inorganic biochemistry.

Carbon-13 NMR studies of C2H5N13C bound to hemoproteins - evidence for a different distal proteic environment in beta-chains either isolated or within human hemoglobin.

D. Mansuy, J. Lallemand, J. Thillet, 1978, Biochemical and biophysical research communications.

In vivo effects of immunostimulating lipopeptides on mouse liver microsomal cytochromes P-450 and on paracetamol-induced toxicity

M. Delaforge, D. Mansuy, P. Jollès, 1989, Experientia.

Iron meso-tetra(2,6-dichlorophenyl)porphyrin as a very efficient catalyst for the photoreduction of carbon tetrachloride by alcohols

D. Mansuy, A. Maldotti, C. Bartocci, 1989 .

New Recognition Elements in Biosensing

V. Erdmann, U. Wollenberger, F. Scheller, 1998 .

Unstability of cinnabarinic acid, an endogenous metabolite of tryptophan, under situations mimicking physiological conditions.

J. Boucher, D. Mansuy, Rogelio J Gómez-Piñeiro, 2022, Biochimie.

Biotransformation of chloroform by rat and human liver microsomes; in vitro effect on some enzyme activities and mechanism of irreversible binding to macromolecules.

P. Beaune, D. Mansuy, T. Cresteil, 1979, Chemico-biological interactions.

Formation of a ferric carbanion complex from halothane and cytochrome P-450: electron spin resonance, electronic spectra, and model complexes

H. Ruf, D. Mansuy, W. Nastainczyk, 1984 .

Immunostimulating lipopeptide, LtriP (RP 56142): Comparison of the effect on hepatic cytochrome P 450 modulation and radioprotection in male and female of three mouse strains

M. Delaforge, D. Mansuy, P. Jollès, 1995, Experientia.

A heme model system for the reduction of substrates by microsomal cytochrome P 450.

D. Mansuy, M. Fontecave, 1982, Biochemical and biophysical research communications.

The reduction of polyhalogenated methanes by liver microsomal cytochrome P450.

D. Mansuy, C. Wolf, W. Nastainczyk, 1977, Molecular pharmacology.

Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation.

D. Mansuy, A. Vessières, G. Jaouen, 2016, Angewandte Chemie.

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

D. Mansuy, A. Vessières, G. Jaouen, 2015, ChemMedChem.

Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile.

J. Boucher, D. Mansuy, F. Acher, 2008, Bioorganic & medicinal chemistry.

A new potent inhibitor of lipid peroxidation in vitro and in vivo, the hepatoprotective drug anisyldithiolthione.

D. Mansuy, P. Dansette, M. Plat, 1986, Biochemical and biophysical research communications.

Metabolism of Anethole Dithiolethione by Rat and Human Liver Microsomes: Formation of Various Products Deriving from Its O-Demethylation and S-Oxidation. Involvement of Cytochromes P450 and Flavin Monooxygenases in These Pathways

J. Boucher, D. Mansuy, P. Dansette, 2018, Drug Metabolism and Disposition.

Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2

D. Mansuy, D. Zeldin, P. Lafite, 2018, International journal of molecular sciences.

Toward stable electron paramagnetic resonance oximetry probes: synthesis, characterization, and metabolic evaluation of new ester derivatives of a tris-(para-carboxyltetrathiaaryl)methyl (TAM) radical.

J. Boucher, D. Mansuy, G. Bertho, 2013, Chemical research in toxicology.

Microsomal formation of nitric oxide and cyanamides from non-physiological N-hydroxyguanidines: N-hydroxydebrisoquine as a model substrate.

J. Boucher, D. Mansuy, B. Clement, 1999, Biochemical pharmacology.

In vitro interaction of rat liver cytochromes P-450 with erythromycin, oleandomycin and erythralosamine derivatives. Importance of structural factors.

M. Delaforge, D. Mansuy, E. Sartori, 1989, Biochemical pharmacology.

In vivo and in vitro effects of a new macrolide antibiotic roxithromycin on rat liver cytochrome P-450: comparison with troleandomycin and erythromycin.

M. Delaforge, D. Mansuy, E. Sartori, 1988, Chemico-biological interactions.

In vivo formation of σ-methyl- and σ-phenyl-ferric complexes of hemoglobin and liver-cytochrome P-450 upon treatment of rats with methyl- and phenylhydrazine

M. Delaforge, D. Mansuy, J. Mahy, 1986 .

Some erythromycin derivatives are strong inducers in rats of a cytochrome P-450 very similar to that induced by 16 alpha-pregnenolone carbonitrile.

P. Beaune, M. Delaforge, D. Mansuy, 1985, Biochemical and biophysical research communications.

Suicidal inactivation of microsomal cytochrome p-450 by hydrazones

D. Mansuy, J. Mahy, P. Battioni, 1985 .

The cytochrome P-450 metabolite complex derived from troleandomycin: properties in vitro and stability in vivo.

M. Delaforge, D. Mansuy, M. Jaouen, 1984, Chemico-biological interactions.

Reduction of benzyl halides by liver microsomes. Formation of 478 NM-absorbing sigma-alkyl-ferric cytochrome P-450 complexes.

D. Mansuy, M. Fontecave, 1983, Biochemical pharmacology.

Reaction of monosubstituted hydrazines and diazenes with rat-liver cytochrome P450. Formation of ferrous-diazene and ferric sigma-alkyl complexes.

M. Delaforge, D. Mansuy, J. Mahy, 1983, European journal of biochemistry.

Kinetic nature of the inhibition of a mixed-function oxidase by hydroxylamines; effect of the pretreatment of rats by inducing agents.

D. Mansuy, E. Rouer, J. Leroux, 1982, Biochimie.

Induction of cytochrome P-450 in rat liver by the antibiotic troleandomycin: partial purificaton and properties of cytochrome P-450-troleandomycin metabolite complexes.

P. Beaune, M. Delaforge, D. Mansuy, 1981, Biochemical and biophysical research communications.

Spectral characterization of cytochrome P-450 of a strain of Candida tropicalis grown on tetradecane.

D. Mansuy, J. Bertrand, M. Carlier, 1980, European journal of biochemistry.

Superoxide anion efficiently performs the oxidative cleavage of CNOH bonds of amidoximes and N-hydroxyguanidines with formation of nitrogen oxides

J. Boucher, D. Mansuy, P. Battioni, 1995 .

Partial purification of human liver cytochrome P 450.

P. Beaune, D. Mansuy, P. Dansette, 1979, Biochemical and biophysical research communications.

Oxidative metabolism of linoleic acid by human leukocytes.

J. Boucher, M. Delaforge, D. Mansuy, 1989, Biochemical and biophysical research communications.

Metabolism of lipoxins A4 and B4 and of their all-trans isomers by human leukocytes and rat liver microsomes.

J. Boucher, M. Delaforge, D. Mansuy, 1991, Biochemical and biophysical research communications.

Importance of valine 567 in substrate recognition and oxidation by neuronal nitric oxide synthase.

J. Boucher, D. Mansuy, M. Sari, 2004, Journal of inorganic biochemistry.

Iron- and manganese-porphyrin catalysed aziridination of alkenes by tosyl- and acyl-iminoiodobenzene

D. Mansuy, J. Mahy, G. Bedi, 1984 .

Detection of human hepatitis anti-liver kidney microsomes (LKM2) autoantibodies on rat liver sections is predominantly due to reactivity with rat liver P-450 IIC11.

D. Mansuy, C. Wolf, P. Dansette, 1991, The Journal of pharmacology and experimental therapeutics.

Clean oxidation of thiolates to sulfinates in a four-coordinate CoIII complex with a mixed carboxamido N-thiolato S donor set: relevance to nitrile hydratase.

D. Mansuy, J. Vaissermann, I. Artaud, 2001, Journal of inorganic biochemistry.

A new general method for selective β-polynitrationof porphyrins; preparation and redox properties of Zn-porphyrins bearingone through to eight β-nitro substituents and X-ray structure of thefirst Zn β-pernitro porphyrin

D. Mansuy, P. Leduc, K. Barkigia, 2000 .

Oxidative and reductive metabolism of tris(p-carboxyltetrathiaaryl)methyl radicals by liver microsomes.

J. Boucher, D. Mansuy, G. Bertho, 2009, Chemical research in toxicology.

Post-translational modification of Rhodococcus R312 and Comamonas NI1 nitrile hydratases.

D. Mansuy, M. Sari, M. Belghazi, 2003, Journal of mass spectrometry : JMS.

Key role of alkanoic acids on the spectral properties, activity, and active-site stability of iron-containing nitrile hydratase from Brevibacterium R312.

D. Mansuy, D. Pétré, I. Artaud, 1996, European journal of biochemistry.

Structural and spectroscopic characterization of a five-coordinate {Fe(NO)}6 complex derived from an iron complex with carboxamido N and thiolato S donors

D. Mansuy, A. Chauvin, I. Artaud, 2002 .

Highly efficient control of iron‐containing nitrile hydratases by stoichiometric amounts of nitric oxide and light

D. Mansuy, D. Pétré, C. Moali, 1997, FEBS letters.

Reduction of ferric haemoproteins by tetrahydropterins: a kinetic study.

D. Mansuy, C. Capeillère-Blandin, D. Mathieu, 2005, The Biochemical journal.

Sulfur containing compounds as antioxidants.

D. Mansuy, P. Dansette, C. Deschamps, 1990, Advances in experimental medicine and biology.

Biocatalysis and substrate chemodiversity: Adaptation of aerobic living organisms to their chemical environment

D. Mansuy, 2008 .

Formation of nitrogen oxides including NO from oxidative cleavage of CN(OH) bonds: A general cytochrome P450-dependent reaction.

J. Boucher, M. Delaforge, D. Mansuy, 1995 .

Cytochromes P-450 and model systems: great diversity of catalyzed reactions

D. Mansuy, 1994 .

Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes.

Eric F. Johnson, D. Mansuy, P. Dansette, 2003, Biochemistry.

The stimulatory effects of asbestos on NADPH-dependent lipid peroxidation in rat liver microsomes.

D. Mansuy, M. Fontecave, M. Jaouen, 1987, The Biochemical journal.

Alkane hydroxylation catalyzed by metalloporhyrins : evidence for different active oxygen species with alkylhydroperoxides and iodosobenzene as oxidants.

D. Mansuy, M. Momenteau, J. Bartoli, 1982 .

Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily.

D. Mansuy, P. Dansette, C. Marques-Soares, 2001, Journal of medicinal chemistry.

Spectroscopic Characterization of an FeIV Intermediate Generated by Reaction of XO− (X = Cl, Br) with an FeII Complex Bearing a Pentadentate Non-Porphyrinic Ligand − Hydroxylation and Epoxidation Activity

D. Mansuy, T. Mattioli, E. Bill, 2004 .

Dehydration of alkyl- and arylaldoximes as a new cytochrome P450-catalyzed reaction: mechanism and stereochemical characteristics.

J. Boucher, M. Delaforge, D. Mansuy, 1994, Biochemistry.

Microperoxidase 8 catalyzed nitration of phenol by nitrogen dioxide radicals.

J. Boucher, D. Mansuy, J. Mahy, 2001, European journal of biochemistry.

First Synthesis of a Binuclear [Mn(II)(bipy)-Fe(III)(porphyrin)] Complex: Spectroscopic Characterization and First Evidence of Reversible Formation of Manganese(III) as Manganese Peroxidase.

D. Mansuy, C. Policar, I. Artaud, 1996, Inorganic chemistry.

Non-heme iron polyazadentate complexes as catalysts for oxidations by H2O2: particular efficiency in aromatic hydroxylations and beneficial effects of a reducing agent

D. Mansuy, V. Balland, J. Girerd, 2004 .

One-pot dodecanitration of Zn(II) and Ni(II) meso-tetrakis-(2,6-dichlorophenyl) porphyrin, and extreme redox properties of the obtained complexes

D. Mansuy, P. Leduc, P. Battioni, 2002 .

Pernitrated metalloporphyrins as catalysts in oxidation with magnesium monoperoxophthalate: I. Epoxidation of cyclic olefins

D. Mansuy, J. Haber, J. Połtowicz, 2000 .

New manganese β-polynitroporphyrins as particularly efficient catalysts for biomimetic hydroxylation of aromatic compounds with H2O2

D. Mansuy, Virginie Mouriès‐Mansuy, P. Battioni, 2000 .

A new manganese-β-heptanitro-porphyrin with extreme redox potentials: spectral, electrochemical and catalytic properties

D. Mansuy, P. Leduc, P. Battioni, 1998 .

Metalloporphyrinosilicas: a new class of hybrid organic–inorganic materials acting as selective biomimetic oxidation catalysts

D. Mansuy, M. Louloudi, G. Spyroulias, 1996 .

Thiophene S-oxides: convenient preparation, first complete structural characterization and unexpected dimerization of one of them, 2,5-diphenylthiophene-1-oxide

D. Mansuy, J. Mornon, P. Dansette, 1995 .

Ammonium acetate as a very simple and efficient cocatalyst for manganese porphyrin-catalysed oxygenation of hydrocarbons by hydrogen peroxide

D. Mansuy, A. Thellend, P. Battioni, 1994 .

Synthesis and remarkable properties of iron β-polynitroporphyrins as catalysts for monooxygenation reactions

D. Mansuy, P. Battioni, J. Bartoli, 1994 .

Oxidation of Cyclohexane Catalyzed by Polyhalogenated and Perhalogenated Iron Porphyrins

D. Mansuy, J. Haber, P. Battioni, 1993 .

Metabolism of polychlorinated phenols by Pseudomonas cepacia AC1100: determination of the first two steps and specific inhibitory effect of methimazole

D. Mansuy, Y. Bertheau, I. Artaud, 1995, Journal of bacteriology.

Interaction of cationic porphyrins with DNA: importance of the number and position of the charges and minimum structural requirements for intercalation.

D. Mansuy, M. Sari, J. Le Pecq, 1990, Biochemistry.

Highly oxidation resistant inorganic-porphyrin analog polyoxometalate oxidation catalysts. 2. Catalysis of olefin epoxidation and aliphatic and aromatic hydroxylations starting from .alpha.2-P2W17O61(Mn+.cntdot.Br)(n-11) (Mn+ = Mn3+,Fe3+,Co2+,Ni2+,Cu2+), including quantitative comparisons to metallo

D. Mansuy, D. Lyon, R. Finke, 1991 .

Hydroxylation of linear alkanes catalysed by iron porphyrins: particular efficacy and regioselectivity of perhalogenated porphyrins

D. Mansuy, P. Battioni, J. Bartoli, 1991 .

Formation of an iron(III)-porphyrin complex with a nitrene moiety inserted into an iron-nitrogen bond during alkene aziridination by (tosylimidoiodo)benzene catalyzed by iron(III) porphyrins

D. Mansuy, J. Mahy, P. Battioni, 1986 .

Iron porphyrin-nitrene complexes: preparation from 1,1-dialkylhydrazines. Electronic structure from NMR, Moessbauer, and magnetic susceptibility studies and crystal structure of the [tetrakis(p-chlorophenyl)porphyrinato][(2,2,6,6-tetramethyl-1-piperidyl)nitrene]iron complex

P. Gans, D. Mansuy, J. Mahy, 1984 .

Isolation of an iron-nitrene complex from the dioxygen- and iron porphyrin-dependent oxidation of a hydrazine

D. Mansuy, J. Mahy, P. Battioni, 1982 .

New intermediate-spin chloroiron(III) complex with a mixed nitrogen– sulfur co-ordination sphere‡

D. Mansuy, I. Artaud, J. Tuchagues, 1998 .

Monooxygenase-like oxidation of hydrocarbons by hydrogen peroxide catalyzed by manganese porphyrins and imidazole: selection of the best catalytic system and nature of the active oxygen species

D. Mansuy, J. Renaud, P. Battioni, 1988 .

Regioselectivity of olefin oxidation by iodosobenzene catalyzed by metalloporphyrins : control by the catalyst

D. Mansuy, M. Fontecave, P. Dansette, 1984 .

Iron porphyrin-catalyzed oxidation of 1,2-dimethoxyarenes : a discussion of the different reactions involved and the competition between the formation of methoxyquinones or muconic dimethyl esters

D. Mansuy, I. Artaud, Khaled Ben-Aziza, 1993 .

Monooxygenase-like oxidations of olefins and alkanes catalyzed by manganese porphyrins : comparison of systems involving either O2 and ascorbate or iodosylbenzene

D. Mansuy, M. Fontecave, 1984 .

Activation of alkanes : the biomimetic approach

D. Mansuy, 1993 .

Reactivity of polyhalogenated metalloporphyrins in epoxidation of propene with magnesium monoperoxyphthalate

D. Mansuy, P. Battioni, R. Iwanejko, 1996 .

Reactivity of polyhalogenated and zeolite-encapsulated metalloporphyrins in oxidation with dioxygen

D. Mansuy, J. Połtowicz, F. Sánchez, 1996 .

Interactions of DNA with a new electron-deficient tentacle porphyrin: meso-tetrakis[2,3,5,6-tetrafluoro-4-(2-t rimethylammoniumethyl-amine)phenyl]porphy rin.

D. Mansuy, L. Marzilli, L. Baudouin, 1997, Biopolymers.

Relationship between the structure of guanidines and N‐hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS‐catalysed oxidation to NO

J. Boucher, D. Mansuy, D. Stuehr, 2005, The FEBS journal.

Reactions between iron porphyrins and tetrahydropterins

J. Boucher, D. Mansuy, P. Battioni, 2004 .

Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s.

J. Boucher, S. Vadon, M. Delaforge, 1993, Biochemical and biophysical research communications.

N omega-hydroxyl-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase.

J. Boucher, S. Vadon, M. Delaforge, 1994, Biochemical and biophysical research communications.

Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine.

J. Boucher, D. Mansuy, M. Sari, 1998, Biochemistry.

Substrate Specificity of NO Synthases: Detailed Comparison of l-Arginine, Homo-l-arginine, Their Nω-Hydroxy Derivatives, and Nω-Hydroxynor-l-arginine†

J. Boucher, D. Mansuy, M. Sari, 1998 .

Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450.

D. Mansuy, D. Zeldin, W. Campbell, 2003, Archives of biochemistry and biophysics.

The Role of Drug Metabolism in Immune-Mediated Drug Toxicity : Molecular , Clinical and Mechanistic Aspects Poster

D. Mansuy, G. Bertho, P. Dansette, 2013 .

Shape selectivity for alkane hydroxylation with a new class of phosphonate-based heterogenised manganese porphyrins

D. Mansuy, C. Pinel, F. Odobel, 1998 .

Thiophene sulfoxides as reactive metabolites: formation upon microsomal oxidation of a 3-aroylthiophene and fate in the presence of nucleophiles in vitro and in vivo.

D. Mansuy, P. Dansette, P. Valadon, 1996, Chemical research in toxicology.

New Biological Reactive Intermediates

D. Mansuy, P. Dansette, 1996 .

New biological reactive intermediates: metabolic activation of thiophene derivatives.

D. Mansuy, P. Dansette, 1996, Advances in experimental medicine and biology.

Unprecedented ipso aromatic nucleophilic substitution upon oxidative decarboxylation of tris(p-carboxyltetrathiaaryl)methyl (TAM) radicals: a new access to diversely substituted TAM radicals.

T. Prangé, J. Boucher, D. Mansuy, 2011, Chemical communications.

Oxidation of tris-(p-carboxyltetrathiaaryl)methyl radical EPR probes: evidence for their oxidative decarboxylation and molecular origin of their specific ability to react with O2*-.

J. Boucher, D. Mansuy, G. Bertho, 2009, Chemical communications.

Synthesis and evaluation of new ω-borono-α-amino acids as rat liver arginase inhibitors

J. Boucher, D. Mansuy, F. Carreaux, 2005 .

The new alpha-amino acid N-omega-hydroxy-nor-L-arginine: A high-affinity inhibitor of arginase well adapted to bind to its manganese cluster

M. Delaforge, D. Mansuy, C. Moali, 1997 .

Nω-Hydroxyamino-α-amino acids as a new class of very strong inhibitors of arginases

J. Boucher, S. Vadon, M. Delaforge, 1996, JBIC Journal of Biological Inorganic Chemistry.

A new easy access to quinones from iron porphyrin-catalysed oxidation of methoxyarenes by magnesium monoperoxyphthalate

D. Mansuy, I. Artaud, C. Chopard, 1991 .

Sulfenic acids as reactive intermediates in xenobiotic metabolism.

D. Mansuy, P. Dansette, 2011, Archives of biochemistry and biophysics.

Selective oxidative cleavage of 1,2-dimethoxyarenes to muconic diesters catalysed by an iron β-sulfonated-tetrakis(pentafluorophenyl)porphyrin

D. Mansuy, H. Grennberg, I. Artaud, 1992 .

Interaction of anions with rat liver arginase: specific inhibitory effects of fluoride.

J. Boucher, D. Mansuy, S. Pèthe, 2002, Journal of inorganic biochemistry.

FTIR and carbon-13 NMR spectra of chalcocarbonyl(5,10,15, 20-tetraphenylporphinato)iron(II) complexes

D. Mansuy, I. Butler, A. Ismail, 1986 .

Carbon-13 NMR studies of C2H5N13C binding to various hemoproteins.

D. Mansuy, J. Lallemand, J. Chottard, 1976, Biochemical and biophysical research communications.

On the mechanism of nitric oxide formation upon oxidative cleavage of C = N(OH) bonds by NO-synthases and cytochromes P450.

J. Boucher, D. Mansuy, B. Clement, 1995, Biochimie.

Hydroxylation of leukotriene B4 in leukocytes from various species: identification of a metabolite to authentic 5S,12R,19-trihydroxy-6Z,8E,10E,14Z-eicosatetra enoic acid and relative importance of 19- and 20-hydroxylations.

J. Boucher, M. Delaforge, D. Mansuy, 1989, Biochemical and biophysical research communications.

Study of the coordination chemistry of prostaglandin G/H synthase by resonance Raman spectroscopy.

D. Mansuy, J. Mahy, S. Gaspard, 1996, European journal of biochemistry.

Nitrosoalkanes as Fe(II) ligands in the hemoglobin and myoglobin complexes formed from nitroalkanes in reducing conditions.

D. Mansuy, G. Chottard, J. Chottard, 1977, European journal of biochemistry.

Hypoactivity of cytochrome P-450 after triacetyloleandomycin administration.

D. Pessayre, D. Mansuy, G. Feldmann, 1981, Biochemical pharmacology.

Structure-activity relationships for DNA photocleavage by cationic porphyrins.

D. Mansuy, L. Perrouault, D. Croke, 1993, Journal of photochemistry and photobiology. B, Biology.

Toward model complexes of Co-containing nitrile hydratases: synthesis, complete characterization and reactivity toward ligands such as CN- and NO of the first square planar CoIII complex with two different carboxamido nitrogens and two thiolato sulfur donors.

D. Mansuy, I. Artaud, J. Tuchagues, 2000, Journal of inorganic biochemistry.

Mode of interaction and apparent binding constants of meso-tetraaryl porphyrins bearing between one and four positive charges with DNA.

D. Mansuy, J. Le Pecq, J. Battioni, 1986, Biochemical and biophysical research communications.

Manganese Porphyrins Adsorbed or Intercalated in Different Mineral Matrices: Preparation and Compared Properties as Catalysts for Alkene and Alkane Oxidation

D. Mansuy, M. Tournoux, W. Jones, 1992 .

Reactivity of the heme–dioxygen complex of the inducible nitric oxide synthase in the presence of alternative substrates

J. Boucher, D. Mansuy, D. Stuehr, 2006, The FEBS journal.

Peroxidase-like activity of lipoxygenases: different substrate specificity of potato 5-lipoxygenase and soybean 15-lipoxygenase and particular affinity of vitamin E derivatives for the 5-lipoxygenase.

D. Mansuy, J. Battioni, R. Daniel, 1991, Biochimica et biophysica acta.

Soybean lipoxygenase-catalyzed oxidations by linoleic acid hydroperoxide: different reducing substrates and dehydrogenation of phenidone and BW 755C.

D. Mansuy, B. Biatry, J. Battioni, 1988, Biochemical and biophysical research communications.

Formation and fate of iron-carbene complexes in reactions between a diazoalkane and iron-porphyrins: relevance to the mechanism of formation of N-substituted hemes in cytochrome P-450-dependent oxidation of sydnones

D. Mansuy, I. Artaud, P. Leduc, 1990 .

Heme model studies related to cytochrome P-450 reactions: preparation of iron porphyrin complexes with carbenes bearing a .beta.-oxygen atom and their transformation into iron-N-alkylporphyrins and iron-metallacyclic complexes

D. Mansuy, I. Artaud, D. Dupré, 1988 .

Comparison of u.v.–visible spectra of iron(I)–porphyrin– and iron(II)–porphyrin (thiolato)-(thiocarbonyl) and -(carbene) complexes. Relevance to ferrous cytochrome P450 complexes

D. Mansuy, J. Savéant, D. Lexa, 1981 .

Dichlorocarbene Complexes of Iron(II)‐Porphyrins–Crystal and Molecular Structure of Fe(TPP)(CCl2)(H2O)

D. Mansuy, B. Chevrier, R. Weiss, 1978 .

Comparison of wild type neuronal nitric oxide synthase and its Tyr588Phe mutant towards various L-arginine analogues.

J. Boucher, D. Mansuy, Toru Shimizu, 2010, Journal of inorganic biochemistry.

The mechanism of halothane binding to microsomal cytochrome P450

D. Mansuy, W. Nastainczyk, V. Ullrich, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Soybean lipoxygenases-1, -2a, -2b and -2c do not contain PQQ.

D. Mansuy, V. Ullrich, I. Michaud-Soret, 1990, Biochemical and Biophysical Research Communications - BBRC.

Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity.

J. Boucher, D. Mansuy, D. Stuehr, 2001, Chemical research in toxicology.

The New α-Amino Acid Nω-Hydroxy-nor-L-arginine: A High- Affinity Inhibitor of Arginase Well Adapted to Bind to Its Manganese Cluster.

J. Boucher, M. Delaforge, D. Mansuy, 1997 .

Formation of a complex with a carbide bridge between two iron atoms from the reaction of (tetraphenylporphyrin)iron(II) with carbon tetraiodide

D. Mansuy, J. Lecomte, J. Bartoli, 1981 .

The chemistry of N-alkylporphyrin complexes. A comparison of reactivities and structures of chlorozinc(II) complexes of N-benzyl-, N-methyl-, and N-phenyltetraphenylporphyrin

D. Mansuy, O. P. Anderson, C. Schauer, 1987 .

Efficient metalloporphyrin synthesis under mild conditions using N-benzylporphyrins.

D. Mansuy, A. White, D. Lavallee, 1986 .

Air-stable, electron-deficient Fe(II) catalytic porphyrins. Characterization and molecular structures of rare high spin Fe(II) hexacoordinated porphyrins.

D. Mansuy, M. Nogués, F. Varret, 2002, Inorganic chemistry.

One-electron oxidation of vinylidene-carbene complexes of iron porphyrins. Isolation of complexes spectrally analogous to catalase and horseradish peroxidase compounds I

D. Mansuy, J. Chottard, M. Lange, 1979 .

Alternative nitric oxide-producing substrates for NO synthases.

J. Boucher, D. Mansuy, 2004, Free radical biology & medicine.

OXIDATION OF N-HYDROXYGUANIDINES BY CYTOCHROMES P450 AND NO-SYNTHASES AND FORMATION OF NITRIC OXIDE

J. Boucher, D. Mansuy, 2002, Drug metabolism reviews.

13C nuclear magnetic resonance studies of the binding of alkyl isocyanides to soybean leghemoglobin; comparison with animal myoglobins.

D. Mansuy, J. Lallemand, F. Stetzkowski, 1980, Biochimie.

Polymeric polyhalogenated metalloporphyrin catalysts for hydroxylation of alkanes and epoxidation of alkenes

D. Mansuy, T. Traylor, P. Battioni, 1991 .

Manganese porphyrins supported on montmorillonite as hydrocarbon mono-oxygenation catalysts: particular efficacy for linear alkane hydroxylation

D. Mansuy, P. Battioni, L. Barloy, 1990 .

Mono-oxygenase-like oxidation of hydrocarbons using supported manganese–porpnyrin catalysts: beneficial effects of a silica support for alkane hydroxylation

D. Mansuy, P. Battioni, L. Barloy, 1989 .

Comparison of the hemoglobin reactions with methyl- and phenyl-hydrazine; intermediate formation of a hemoglobin Fe-(II)-methyldiazene complex.

D. Mansuy, J. Mahy, P. Battioni, 1982, Biochemical and Biophysical Research Communications - BBRC.

Hemoprotein models based on a covalent helix-heme-helix sandwich. 3. Coordination properties, reactivity and catalytic application of Fe(III)- and Fe(II)-mimochrome I

D. Mansuy, G. Morelli, A. Lombardi, 1998, JBIC Journal of Biological Inorganic Chemistry.

Reactions of prostaglandin H synthase with monosubstituted hydrazines and diazenes. Formation of iron(II)-diazene and iron(III)-sigma-alkyl or iron(III)-sigma-aryl complexes.

M. Delaforge, D. Mansuy, J. Mahy, 1994, European journal of biochemistry.

Formation of complexes between microsomal cytochrome P-450-Fe(II) and nitrosoarenes obtained by oxidation of arylhydroxylamines or reduction of nitroarenes in situ.

P. Beaune, P. Gans, D. Mansuy, 1978, European journal of biochemistry.

New Catalytic Properties of Iron Porphyrins: Model Systems for Cytochrome P450-Catalyzed Dehydration of Aldoximes

J. Boucher, D. Mansuy, P. Battioni, 1998 .

Cytochrome P-450 and synthetic models

D. Mansuy, 1987 .

Biomimetic catalysts for selective oxidation in organic chemistry

D. Mansuy, 1990 .

Comparison of Various Aryl-Dithiolethiones and Aryl-Dithiolones As Hydrogen Sulfide Donors in the Presence of Rat Liver Microsomes

J. Boucher, D. Mansuy, P. Dansette, 2020, Drug Metabolism and Disposition.

Autoantibodies against cytochromes P450: role in human diseases.

M. Manns, P. Beaune, D. Pessayre, 1994, Advances in pharmacology.

Photocatalytic oxidation of cyclohexane by (nBu4N)4W10O32Fe(III)prophyrins integrated systems

D. Mansuy, A. Maldotti, A. Molinari, 1996 .

Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.

J. Boucher, D. Mansuy, D. Christianson, 2001, Biochemistry.

Mechanisms of inactivation of lipoxygenases by phenidone and BW755C.

D. Mansuy, N. Nam, J. Battioni, 1991, Biochemistry.

Reaction of carbon tetrachloride with 5,10,15,20-tetraphenyl-porphinatoiron(II)[(TPP)FeII]: evidence for the formation of the carbene complex [(TPP)FeII(CCl2)]

D. Mansuy, M. Rougée, P. Morlière, 1977 .

Iron porphyrin dependent oxidation of methyl- and phenylhydrazine: isolation of iron(II)-diazene and .sigma.-alkyliron(III) [or aryliron(III)] complexes. Relevance to the reactions of hemoproteins with hydrazines

D. Mansuy, J. Mahy, P. Battioni, 1983 .

Structure-activity relationships in the inhibitory effects of ellipticines on benzo(a)pyrene hydroxylase activity and 3-methylcholanthrene mutagenicity.

D. Mansuy, C. Paoletti, D. Pélaprat, 1980, Biochemical pharmacology.

Microperoxidase 8 catalysed nitrogen oxides formation from oxidation of N-hydroxyguanidines by hydrogen peroxide.

J. Boucher, D. Mansuy, J. Mahy, 2002, European Journal of Biochemistry.

CoII Complexes with Mixed Amino-N and Thiolato-S Donor Sets − Structural Characterization and Electronic Properties of a Stable Bis(μ-thiolato)-Bridged Binuclear CoII Complex

D. Mansuy, E. Bill, I. Artaud, 2001 .

A brief history of the contribution of metalloporphyrin models to cytochrome P450 chemistry and oxidation catalysis

D. Mansuy, Daniel Mansuy, 2007 .

Synthesis and spectroscopic, electrochemical, and catalytic properties of a new manganese porphyrin bearing four positive charges close to the metal

D. Mansuy, P. Dansette, Y. Frapart, 2007 .

Oxidation of arylamidoximes by various chemical and biomimetic systems: comparison with their oxidations by hemeproteins

J. Boucher, D. Mansuy, Sandrine Vadon-Le Goff, 2000 .

N-substituted porphyrins formation from carbene iron-porphyrin complexes: a possible pathway for cytochrome P450 heme destruction.

D. Mansuy, M. Lange, 1981 .

Asymmetric epoxidation of alkenes catalysed by a basket-handlë iron-porphyrin bearing amino acids

D. Mansuy, J. Renaud, P. Guérin, 1985 .

The substrate binding site of human liver cytochrome P450 2C9: an NMR study.

D. Mansuy, P. Dansette, D Mansuy, 1997, Biochemistry.

A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties

D. Mansuy, G. Jaouen, P. Pigeon, 2017, Chemical science.

Redox properties of photoexcited (nBu4N)3PW12O40FeIII porphyrins composite systems

D. Mansuy, R. Argazzi, A. Maldotti, 1996 .

Microsomal cytochrome P450 dependent oxidation of N-hydroxyguanidines, amidoximes, and ketoximes: mechanism of the oxidative cleavage of their C=N(OH) bond with formation of nitrogen oxides.

J. Boucher, D. Mansuy, B. Clement, 1998, Biochemistry.

OXIDATION OF N-HETEROCYCLES BY H2O2 CATALYZED BY A MN-PORPHYRIN: AN EASY ACCESS TO N-OXIDES UNDER MILD CONDITIONS

D. Mansuy, A. Thellend, P. Battioni, 1997 .

Manganese porphyrins covalently bound to silica and montmorillonite K10 as efficient catalysts for alkene and alkane oxidation by hydrogen peroxide

D. Mansuy, P. Battioni, J. Bartoli, 1996 .

New Metalloporphyrins with Extremely Altered Redox Properties: Synthesis, Structure, and Facile Reduction to Air-Stable π-Anion Radicals of Zinc and Nickel β-Heptanitroporphyrins

D. Mansuy, P. Leduc, K. Barkigia, 1997 .

Oxidation of monosubstituted olefins by cytochromes P-450 and heme models: evidence for the formation of aldehydes in addition to epoxides and allylic alcohols.

D. Mansuy, M. Fontecave, M. Momenteau, 1984, Biochemical and biophysical research communications.

Oxidation of Cyclohexane by Molecular Oxygen Photoassisted by meso-Tetraarylporphyrin Iron(III)-Hydroxo Complexes.

D. Mansuy, A. Maldotti, C. Bartocci, 1996, Inorganic chemistry.

Dioxygen Activation at Heme Centers in Enzymes and Synthetic Analogs

D. Mansuy, P. Battioni, 1999 .

Oxidation of arylamidoximes by hydrogen peroxide and horseradish peroxidase in water: Easy preparation and X-ray structure of O-(arylimidoyl)arylamidoximes

J. Boucher, S. Vadon, D. Mansuy, 1996 .

Reduction of the Fe(III)-tyrosyl radical center of Escherichia coli ribonucleotide reductase by dithiothreitol.

D. Mansuy, M. Fontecave, P. Reichard, 1990, The Journal of biological chemistry.

A new route to selenocarbonyl-transition-metal complexes: preparation of the (5,10,15,20-tetraphenylporphinato-iron(II)-selenocarbonyl complex, Fe(TPP)(CSe), from the carbenic Fe(TPP)(C(Cl)SeCH2C6H5) complex

D. Mansuy, J. Chottard, J. Battioni, 1980 .

New iron-porphyrin complexes with metal-carbon bond - biological implications

D. Mansuy, 1980 .

Nomega-hydroxy-L-arginine homologues and hydroxylamine as nitric oxide-dependent vasorelaxant agents.

J. Boucher, D. Mansuy, T. Munzel, 2005, European journal of pharmacology.

Inhibitor coordination interactions in the binuclear manganese cluster of arginase.

J. Boucher, D. Mansuy, D. Christianson, 2004, Biochemistry.

Mono-oxigenase-like dioxygen activation leading to alkane hydroxylation and olefin epoxidation by an MnIII(porphyrin)–ascorbate biphasic system

D. Mansuy, M. Fontecave, J. Bartoli, 1983 .

Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes.

J. Boucher, M. Delaforge, D. Mansuy, 2001, Biochemical and biophysical research communications.

Interaction of cis-diaquodiammineplatinum dinitrate with ribose dinucleoside monophosphates

D. Mansuy, J. Lallemand, J. Girault, 1980 .

Nitrosoalkane complexes of iron-porphyrins: analogy between the bonding properties of nitrosoalkanes and dioxygen

D. Mansuy, A. Chiaroni, P. Battioni, 1983 .

In vitro metabolism of isaxonine phosphate: formation of two metabolites, 5-hydroxyisaxonine and 2-aminopyrimidine, and covalent binding to microsomal proteins.

J Leclaire, D. Mansuy, P. Dansette, 1992, European journal of pharmacology.

Hydroxylation of the thiophene ring by hepatic monooxygenases. Evidence for 5-hydroxylation of 2-aroylthiophenes as a general metabolic pathway using a simple UV-visible assay.

D. Mansuy, E. Neau, P. Dansette, 1990, Biochemical pharmacology.

Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes.

D. Mansuy, P. Dansette, C. Smith, 1990, Biochemical pharmacology.

On the Investigation by EXAFS Spectroscopy of a Selenocarbonyl Complex (CSe = Fe(II)TPP)

D. Mansuy, J. Goulon, C. Goulon-Ginet, 1983 .

Reductive electrochemistry of iron-carbene porphyrins

D. Mansuy, J. Savéant, D. Lexa, 1983 .

Reversible iron-nitrogen migration of alkyl, aryl, or vinyl groups in iron porphyrins: a possible passage between .sigma. FeIII(porphyrin)(R) and FeII(N-R)(porphyrin)complexes

D. Mansuy, E. Sartori, G. Chottard, 1982 .

Redox Reltionship between Carbeneiron and σ‐Alkyliron Porphyrins

D. Mansuy, J. Savéant, D. Lexa, 1981 .

Preparation of a porphyrin-iron-carbene model for the cytochrome P 450 complexes obtained upon metabolic oxidation of the insecticide synergists of the 1,3-benzodioxole series

D. Mansuy, V. Ullrich, J. Chottard, 1979 .

Nitrene and Carbene Transfer Catalyzed by Metalloporphyrins

D. Mansuy, J. Mahy, 1994 .

Chemical model systems for drug-metabolizing cytochrome-P-450-dependent monooxygenases.

D. Mansuy, P. Battioni, J. Battioni, 1989, European journal of biochemistry.

Photoredox and photocatalytic characteristics of various iron meso-tetraarylporphyrins

D. Mansuy, A. Maldotti, C. Bartocci, 1991 .

The substrate binding site of human liver cytochrome P450 2C9: an approach using designed tienilic acid derivatives and molecular modeling.

D. Mansuy, P. Dansette, P. Broto, 1995, Biochemistry.

Oxidation of N-(4-Chlorophenyl)-N′-hydroxyguanidine to N-(4-Chlorophenyl)urea and Nitric Oxide by Photoexcited Iron Porphyrins

D. Mansuy, A. Maldotti, A. Molinari, 2004 .

A new cytochrome P450 belonging to the 107L subfamily is responsible for the efficient hydroxylation of the drug terfenadine by Streptomyces platensis.

D. Mansuy, M. Sari, D. Buisson, 2011, Archives of biochemistry and biophysics.

Resonance Raman studies of hemoglobin complexes with nitric oxide, nitrosobenzene and nitrosomethane: observation of the metal-ligand vibrations.

D. Mansuy, G. Chottard, 1977, Biochemical and biophysical research communications.

STUDY OF HYDROXYLASE AND ITS COMPONENTS IN CANDIDA TROPICALIS GROWN ON ALKANE

D. Mansuy, J. Bertrand, M. Gilewicz, 1981 .

A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism

J. Latgé, H. Munier-Lehmann, J. Cavaillon, 2018, Antimicrobial Agents and Chemotherapy.

Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug.

P. Beaune, D. Mansuy, P. Dansette, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Anti‐cytochrome P450 autoantibodies in drug‐induced disease

P. Beaune, D. Mansuy, M. Bourdi, 1996, European journal of haematology. Supplementum.

Antigenic targets in tienilic acid hepatitis. Both cytochrome P450 2C11 and 2C11-tienilic acid adducts are transported to the plasma membrane of rat hepatocytes and recognized by human sera.

D. Pessayre, D. Mansuy, M. Maratrat, 1996, The Journal of clinical investigation.

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

P. Beaune, D. Pessayre, D. Mansuy, 2010 .

Coordination chemistry of cytochromes P 450 and iron-porphyrins: relevance to pharmacology and toxicology

D. Mansuy, 1978 .

Evidence for phosgene formation during liver microsomal oxidation of chloroform.

P. Beaune, D. Mansuy, T. Cresteil, 1977, Biochemical and biophysical research communications.

Nitric oxide formation during microsomal hepatic denitration of glyceryl trinitrate: involvement of cytochrome P-450.

M. Delaforge, D. Mansuy, D. Servent, 1989, Biochemical and biophysical research communications.

Automated multiple analysis of protein structures: Application to homology modeling of cytochromes P450

D. Mansuy, A. Viari, J. Pothier, 1997, Proteins.

Interaction of new sulfaphenazole derivatives with human liver cytochrome p450 2Cs: structural determinants required for selective recognition by CYP 2C9 and for inhibition of human CYP 2Cs.

D. Mansuy, M. Sari, P. Dansette, 2001, Archives of biochemistry and biophysics.

Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9.

D. Mansuy, F. Guengerich, P. Guengerich, 1996, Biochemistry.

Interaction of aliphatic N-hydroxylamines with microsomal cytochrome P450: nature of the different derived complexes and inhibitory effects on monoxygenases activities.

P. Gans, D. Mansuy, E. Rouer, 1978, Biochemical pharmacology.

Ellipticines as potent inhibitors of aryl hydrocarbon hydroxylase: their binding to microsomal cytochromes P450 and protective effect against benzo(a)pyrene mutagenicity.

D. Mansuy, C. Paoletti, P. Lesca, 1978, Biochemical pharmacology.

Nitrosoalkanes as Fe(II) ligands in the 455-nm-absorbing cytochrome P-450 complexes formed from nitroalkanes in reducing conditions.

P. Gans, D. Mansuy, J. Bartoli, 1977, European journal of biochemistry.

Preparation of functionalized polyhalogenated tetraaryl-porphyrins by selective substitution of the p-Fluorines of meso-tetra-(pentafluorophenyl)porphyrins

D. Mansuy, H. Desvaux, T. Traylor, 1991 .

Monooxygenation of aromatic compounds by dioxygen with bioinspired systems using non-heme iron catalysts and tetrahydropterins: comparison with other reducing agents and interesting regioselectivity favouring meta-hydroxylation

D. Mansuy, P. Battioni, J. Bartoli, 2004 .

Human Orphan Cytochrome P450 2U1 Catalyzes the ω-Hydroxylation of Leukotriene B4

J. Boucher, D. Mansuy, N. Pietrancosta, 2022, International journal of molecular sciences.

High affinity of ergopeptides for cytochromes P450 3A. Importance of their peptide moiety for P450 recognition and hydroxylation of bromocriptine.

M. Delaforge, D. Mansuy, J. Renaud, 1994, European journal of biochemistry.

THE INTERACTION OF POLYHALOGENATED METHANES WITH FERROUS CYTOCHROME P450

D. Mansuy, C. Wolf, W. Nastainczyk, 1977 .

Metalloporphyrin‐Catalyzed Hydroxylation of Cyclohexane by Alkyl Hydroperoxides: Pronounced Efficiency of Iron‐Porphyrins

D. Mansuy, J. Bartoli, J. Chottard, 1980 .

Hydroxylation and formation of electrophilic metabolites of tienilic acid and its isomer by human liver microsomes. Catalysis by a cytochrome P450 IIC different from that responsible for mephenytoin hydroxylation.

D. Mansuy, P. Dansette, P. Beaune, 1991, Biochemical pharmacology.

Coordination chemistry of iron(III)-porphyrin-antibody complexes.

D. Mansuy, J. Mahy, S. de Lauzon, 2002, European journal of biochemistry.

Deciphering the activation sequence of ferrociphenol anticancer drug candidates.

D. Mansuy, A. Vessières, G. Jaouen, 2012, Chemistry.

Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.

D. Mansuy, D. Zeldin, P. Lafite, 2006, Bioorganic & medicinal chemistry letters.

Microperoxidase 8 (mp8) as a convenient model for hemoproteins: formation and characterisation of new iron(II)-nitrosoalkane complexes of biological relevance.

J. Boucher, D. Mansuy, J. Mahy, 2001, Advances in experimental medicine and biology.

Formation of iron(II)-nitrosoalkane complexes: a new activity of microperoxidase 8.

J. Boucher, D. Mansuy, J. Mahy, 2000, Biochemical and biophysical research communications.

Effects of the new arginase inhibitor N(omega)-hydroxy-nor-L-arginine on NO synthase activity in murine macrophages.

J. Boucher, D. Mansuy, J. Tenu, 1999, Nitric oxide : biology and chemistry.

2-methyl-2-nitrosopropane and nitrosobenzene as nitrogen-bonded platinum(II) ligands. Molecular structure of {PtCl2[(CH3)3C(NO)]2} ☆

D. Mansuy, J. Guilhem, J. Chottard, 1978 .

Nitrosoalkanes as new ligands of iron(II) porphyrins and hemoproteins.

D. Mansuy, P. Battioni, J. Chottard, 1977, Journal of the American Chemical Society.

trans-Bonding bidentate macroligands in platinum(II) complexes

D. Mansuy, J. Girault, E. Mulliez, 1974 .

Metabolic activation of the antitumor drug 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB1954) by NO synthases.

J. Boucher, D. Mansuy, D. Stuehr, 2008, Chemical research in toxicology.

Reaction between 2-methyl-2-nitrosopropane and ethylene coordinated to platinum(II): formation of .sigma.-alkyl-nitrone complexes

D. Mansuy, J. Girault, J. Guilhem, 1980 .

Formation of prostaglandin synthase-iron-nitrosoalkane inhibitory complexes upon in situ oxidation of N-substituted hydroxylamines.

D. Mansuy, J. Mahy, 1991, Biochemistry.

Dual effects of macrolide antibiotics on rat liver cytochrome P-450. Induction and formation of metabolite-complexes: a structure-activity relationship.

M. Delaforge, D. Mansuy, M. Jaouen, 1983, Biochemical pharmacology.

Coordination Chemistry of Cytochrome P-450 and Heme Models

D. Mansuy, 1983 .

Mössbauer study of (2-nitrisopropane)(n-methylimidazole) and (2-nitrosopropane)(isoropylamie) iron(II) tetraphenylporphyrins

D. Mansuy, P. Battioni, J. Regnard, 1980 .

NITROSOALKANES AS NEW LIGANDS OF IRON(II) PORPHYRINS AND HEMOPROTEINS

D. Mansuy, P. Battioni, J. Chottard, 1977 .

TRANS‐BONDING BIDENTATE MACROLIGANDS IN PLATINUM(II) COMPLEXES

D. Mansuy, J. Girault, E. Mulliez, 1974 .

Thiophene 1-oxides. V. Comparison of the crystal structures and thiophene ring aromaticity of 2,5-diphenylthiophene, its sulfoxide and sulfone†‡§¶

D. Mansuy, J. Mornon, P. Dansette, 1997 .

Studies of the reactivity of artificial peroxidase‐like hemoproteins based on antibodies elicited against a specifically designed ortho‐carboxy substituted tetraarylporphyrin

D. Mansuy, J. Mahy, S de Lauzon, 1999, FEBS letters.

Artificial peroxidase‐like hemoproteins based on antibodies constructed from a specifically designed ortho‐carboxy substituted tetraarylporphyrin hapten and exhibiting a high affinity for iron‐porphyrins

D. Mansuy, J. Mahy, B. Desfosses, 1996, FEBS letters.

[Induction of rat hepatic mono-oxygenases by ellipticine: formation of cytochrome p448. Hydroxylating activity].

D. Mansuy, C. Paoletti, P. Lesca, 1976, Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles.

Escherichia coli and herpes-simplex-virus ribonucleotide reductase R2 subunit. Compared reactivities of the redox centres.

D. Mansuy, M. Fontecave, M. Atta, 1993, The Biochemical journal.

Heme-Thiolate Proteins Different from Cytochromes P450 Catalyzing Monooxygenations

D. Mansuy, J. Renaud, 1995 .

Heme-Thiolate Proteins Differentfrom Cytochromes P450 Catalyzing

D. Mansuy, J. Renaud, 1995 .

Aziridination of alkenes catalysed by porphyrinirons: selection of catalysts for optimal efficiency and stereospecificity

D. Mansuy, J. Mahy, G. Bedi, 1988 .

Rapid routes of synthesis of chemically reactive and highly radioactively labeled alpha- and beta-oligonucleotide derivatives for in vivo studies.

D. Mansuy, A. Boutorine, T. Le Doan, 1990, Bioconjugate chemistry.

Amination of alkanes catalyzed by iron- and manganese-porphyrins: particular selectivity for ω and ω−1 oxidations of linear alkanes

D. Mansuy, J. Mahy, G. Bedi, 1990 .

Allylic amination of alkenes by tosyliminoiodobenzene: manganese porphyrins as suitable catalysts

D. Mansuy, J. Mahy, G. Bedi, 1988 .

Aziridination of Alkenes Catalyzed by Porphyrinirons: Selection of Catalysts for Optimal Efficiency and Stereospecificity.

D. Mansuy, J. Mahy, G. Bedi, 1988 .

Biomimetic Oxidation of Hydrocarbons and Drugs by Metalloporphyrinic Systems

D. Mansuy, P. Battioni, 1987 .

Alkene oxidations by iodosylbenzene catalyzed by iron-porphyrins: fate of the catalyst and formation of N-alkyl-porphyrin green pigments from monosubstituted alkenes as in cytochrome P-450 reactions

D. Mansuy, I. Artaud, J. Battioni, 1985 .

Reactions de substitution des sels d'alkoxy-4 pyridinium

P. Mattei, D. Mansuy, H. Langhals, 1976 .

ALKANE HYDROXYLATION CATALYZED BY METALLOPORPHYRINS: EVIDENCE FOR DIFFERENT ACTIVE OXYGEN SPECIES WITH ALKYLHYDROPEROXIDES AND IODOSOBENZENE AS OXIDANTS

D. Mansuy, M. Momenteau, J. Bartoli, 1982 .

The great diversity of reactions catalyzed by cytochromes P450.

D. Mansuy, 1998, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Recombinant yeast in drug metabolism.

P. Beaune, D. Mansuy, J. Renaud, 1993, Toxicology.

Human-liver cytochromes P-450 expressed in yeast as tools for reactive-metabolite formation studies. Oxidative activation of tienilic acid by cytochromes P-450 2C9 and 2C10.

D. Mansuy, F. Guengerich, P. Dansette, 1993, European journal of biochemistry.

Recognition of alpha-amino acids bearing various C=NOH functions by nitric oxide synthase and arginase involves very different structural determinants.

D. Mansuy, M. Sari, D. Stuehr, 2000, Biochemistry.

JunD Reduces Tumor Angiogenesis by Protecting Cells from Oxidative Stress

Fatima Mechta-Grigoriou, A. Giaccia, D. Mansuy, 2004, Cell.

A S-adenosylmethionine methyltransferase-like domain within the essential, Fe-S-containing yeast protein Dre2

A. Pastore, D. Mansuy, B. Raynal, 2012, The FEBS Journal.

REACTION BETWEEN 2-METHYL-2-NITROSOPROPANE AND ETHYLENE COORDINATED TO PLATINUM(II): FORMATION OF Σ-ALKYL-NITRONE COMPLEXES

D. Mansuy, J. Girault, J. Guilhem, 1980 .

A class of strong inhibitors of microsomal monooxygenases: the ellipticines.

D. Mansuy, P. Lesca, P. Lecointe, 1979, Chemico-biological interactions.

Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.

D. Mansuy, D. Zeldin, P. Lafite, 2007, Archives of biochemistry and biophysics.

Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid.

D. Mansuy, P. Dansette, M. López-Garcı́a, 1994, Biochemistry.

Molecular structure and hepatotoxicity: compared data about two closely related thiophene compounds.

D. Mansuy, 1997, Journal of hepatology.

Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: comparison with two directly hepatotoxic drugs.

P. Beaune, D. Mansuy, P. Dansette, 1994, Chemical research in toxicology.

Evidence for thiophene-S-oxide as a primary reactive metabolite of thiophene in vivo: formation of a dihydrothiophene sulfoxide mercapturic acid.

D. Mansuy, H. El Amri, P. Dansette, 1992, Biochemical and biophysical research communications.

The nature of the "455 nm absorbing complex" formed during the cytochrome P450 dependent oxidative metabolism of amphetamine.

P. Beaune, P. Gans, D. Mansuy, 1976, Biochemical pharmacology.

Metabolic hydroxylation of the thiophene ring: isolation of 5-hydroxy-tienilic acid as the major urinary metabolite of tienilic acid in man and rat.

D. Mansuy, N. Bayer, P. Dansette, 1984, Biochemical pharmacology.

Cytochrome P450 2U1, a very peculiar member of the human P450s family

J. Boucher, D. Mansuy, L. Ducassou, 2017, Cellular and Molecular Life Sciences.

First non-alpha-amino acid guanidines acting as efficient NO precursors upon oxidation by NO-synthase II or activated mouse macrophages.

J. Boucher, D. Mansuy, D. Stuehr, 2002, Biochemistry.

Great adaptability of the heme-cysteinate monooxygenases family to very diverse substrates and sophisticated reactions

D. Mansuy, P. Lafite, 2007 .

Critical role of Val567 in substrate recognition by neuronal nitric oxide synthase for NO formation activity

J. Boucher, D. Mansuy, M. Sari, 2003 .

Hexanal phenylhydrazone is a mechanism-based inactivator of soybean lipoxygenase 1.

F. Lederer, D. Mansuy, S. Bombard, 1988, Biochemistry.

Cytochromes P450 of Caenorhabditis elegans: Implication in Biological Functions and Metabolism of Xenobiotics

X. Coumoul, D. Mansuy, J. Dairou, 2022, Biomolecules.

Membrane-bound human orphan cytochrome P450 2U1: Sequence singularities, construction of a full 3D model, and substrate docking.

François André, J. Boucher, D. Mansuy, 2017, Biochimie.

Mechanism of H2S Formation from the Metabolism of Anetholedithiolethione and Anetholedithiolone by Rat Liver Microsomes

J. Boucher, D. Mansuy, P. Dansette, 2019, Drug Metabolism and Disposition.

Thiophene S-oxides as new reactive metabolites: formation by cytochrome P-450 dependent oxidation and reaction with nucleophiles

D. Mansuy, P. Dansette, I. Erdelmeier, 1991 .

Hemoabzymes different strategies for obtaining artificial hemoproteins based on antibodies

D. Mansuy, J. Mahy, B. Desfosses, 1998, Applied biochemistry and biotechnology.

Particular ability of cytochrome P-450 CYP3A to reduce glyceryl trinitrate in rat liver microsomes: subsequent formation of nitric oxide.

M. Delaforge, D. Mansuy, D. Servent, 1993, Chemico-biological interactions.

Metabolic activation of prasugrel: nature of the two competitive pathways resulting in the opening of its thiophene ring.

D. Mansuy, G. Bertho, P. Dansette, 2012, Chemical research in toxicology.

Formation and fate of a sulfenic acid intermediate in the metabolic activation of the antithrombotic prodrug prasugrel.

D. Mansuy, G. Bertho, S. Thébault, 2010, Chemical research in toxicology.

Metabolic oxidative cleavage of thioesters: evidence for the formation of sulfenic acid intermediates in the bioactivation of the antithrombotic prodrugs ticlopidine and clopidogrel.

D. Mansuy, G. Bertho, P. Dansette, 2009, Chemical research in toxicology.

First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives.

Gildas Bertho, D. Mansuy, G. Bertho, 2005, Biochemical and biophysical research communications.

Thiophene S‐Oxides as New Reactive Metabolites: Formation by Cytochrome P450 Dependent Oxidation and Reaction with Nucleophiles.

D. Mansuy, P. Dansette, I. Erdelmeier, 1992 .

Brief historical overview and recent progress on cytochromes P450: adaptation of aerobic organisms to their chemical environment and new mechanisms of prodrug bioactivation.

D. Mansuy, 2011, Annales pharmaceutiques francaises.

Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19.

J. Goldstein, D. Mansuy, P. Dansette, 2001, Biochemistry.

Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes.

C David Stout, Eric F. Johnson, D. Mansuy, 2003, Biochemistry.

Phororedox and photocatalytic processes on Fe(III)–porphyrin surface modified nanocrystalline TiO2

D. Mansuy, A. Maldotti, A. Molinari, 2000 .

First Combined in Vivo X-Ray Tomography and High-Resolution Molecular Electron Paramagnetic Resonance (EPR) Imaging of the Mouse Knee Joint Taking into Account the Disappearance Kinetics of the EPR Probe

Florence Cloppet, Sylvain Durand, Frédéric Richard, 2012, Molecular imaging.

Chemical and Biological Oxidation of Thiophene: Preparation and Complete Characterization of Thiophene S-Oxide Dimers and Evidence for Thiophene S-Oxide as an Intermediate in Thiophene Metabolism in Vivo and in Vitro

D. Mansuy, H. Amri, P. Dansette, 1997 .

On the nature and reactivity towards substrates of the active oxygen hemoprotein complexes involved in the reaction of peroxidases and cytochrome P- 450 with two-electron oxidants

D. Mansuy, J. Chottard, M. Lange, 1980 .

Paraoxonase-1 and clopidogrel efficacy

D. Mansuy, G. Bertho, P. Dansette, 2011, Nature Medicine.

N-hydroxyguanidines as new heme ligands: UV-visible, EPR, and resonance Raman studies of the interaction of various compounds bearing a C=NOH function with microperoxidase-8.

J. Boucher, D. Mansuy, J. Mahy, 2001, Biochemistry.

Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid.

D. Mansuy, M. Sari, Armelle Melet, 2003, Archives of biochemistry and biophysics.

Preparation and properties of iron(II), cobalt(III), and zinc(II) N-alkylporphyrin complexes involving five-membered metal-O-C=C-N metallacycles

D. Mansuy, I. Artaud, P. Leduc, 1987 .

An iron(III)-porphyrin complex with a vinylidene group inserted into an iron-nitrogen bond: relevance to the structure of the active oxygen complex of catalase

D. Mansuy, B. Chevrier, R. Weiss, 1981 .

Isolation of σ-alkyl-iron(III) or carbene-iron(II) complexes from reduction of polyhalogenated compounds by iron(II)-porphyrins: the particular case of halothane CF3CHClBr

D. Mansuy, J. Battioni, 1982 .

Reduction of nilutamide by NO synthases: implications for the adverse effects of this nitroaromatic antiandrogen drug.

J. Boucher, D. Mansuy, M. Sari, 2003, Chemical research in toxicology.

Synthesis of (4-chlorophenyl)-(1-oxo-1λ4-benzo[b]thien-2-yl)methanone and study of its reactivity towards sulfur- and oxygen-containing nucleophiles

D. Mansuy, P. Dansette, I. Erdelmeier, 1998 .

CYP2U1 activity is altered by missense mutations in hereditary spastic paraplegia 56

A. Durr, F. Rivier, G. Stevanin, 2018, Human mutation.

Microsomal lipid peroxidation and oxy-radicals formation are induced by insoluble iron-containing minerals.

D. Mansuy, M. Fontecave, D. Costa, 1990, Biochemical and biophysical research communications.

Electrochemistry of manganese porphyrin intercalated into montmorillonite

D. Mansuy, J. Devynck, F. Bedioui, 1991 .

Efficient formation of nitric oxide from selective oxidation of N-aryl N'-hydroxyguanidines by inducible nitric oxide synthase.

J. Boucher, D. Mansuy, D. Stuehr, 1999, Biochemistry.

Phenylhydrazones as new good substrates for the dioxygenase and peroxidase reactions of prostaglandin synthase: formation of iron(III)-sigma-phenyl complexes.

D. Mansuy, J. Mahy, S. Gaspard, 1993, Biochemistry.

Non-heme iron polyazadentate complexes as catalysts for aromatic hydroxylation by H2O2: Particular efficiency of tetrakis(2-pyridylmethyl)ethylenediamine–iron(II) complexes

D. Mansuy, M. Martinho, R. Guillot, 2008 .

Unusual efficiency of a non-heme iron complex as catalyst for the hydroxylation of aromatic compounds by hydrogen peroxide: comparison with iron porphyrins

D. Mansuy, F. Lambert, P. Battioni, 2002 .

Reactive Intermediates Derived from Cytochrome P-450 Monooxygenases

D. Mansuy, 1983 .

Synthesis and evaluation of new omega-borono-alpha-amino acids as rat liver arginase inhibitors.

J. Boucher, D. Mansuy, F. Carreaux, 2005, Bioorganic & Medicinal Chemistry.

Expression of human liver cytochrome P450 IIIA4 in yeast. A functional model for the hepatic enzyme.

P. Beaune, D. Mansuy, J. Renaud, 1990, European journal of biochemistry.

Reactions of amino acids, peptides, and proteins with oxidized metabolites of tris(p-carboxyltetrathiaaryl)methyl radical EPR probes.

J. Boucher, D. Mansuy, C. Decroos, 2014, Chemical research in toxicology.

An easy access to polyhalogenated metalloporphyrins covalently bound to polymeric supports as efficient catalysts for hydrocarbon oxidation

D. Mansuy, T. Traylor, P. Battioni, 1992 .

REACTION OF IRON(II) TETRAPHENYLPORPHYRIN DICHLOROCARBENE COMPLEX WITH PRIMARY AMINES: FORMATION OF ISONITRILES

D. Mansuy, J. Bartoli, J. Chottard, 1978 .

Synthesis and Catalytic Properties of Manganese Porphyrins Incorporated into Phosphonate Networks

D. Mansuy, J. Rouxel, D. Deniaud, 1995 .

Phosphines as ligands to microsomal cytochrome P-450.

H. Ruf, D. Mansuy, V. Ullrich, 1974, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

Thiocarbonyl complexes of iron(II) porphyrins. Formation by thiophosgene reduction

D. Mansuy, J. Chottard, J. Battioni, 1978 .

Structural Investigations of Biomimetic Complexes of Cytochrome P-450 by Difference EXAFS Spectroscopy

D. Mansuy, J. Mahy, I. Ascone, 1987 .

[Metabolism of xenobiotics: beneficial and adverse effects].

D. Mansuy, 2013, Biologie aujourd'hui.

Chaperone-assisted expression, purification, and characterization of recombinant nitrile hydratase NI1 from Comamonas testosteroni.

D. Mansuy, M. Sari, M. Belghazi, 2003, Protein expression and purification.

Surface Active Sites and Catalytic Properties of Asbestos Mineral. Possible Consequence for their Activity in Biological Medium

D. Mansuy, H. Pezerat, J. Guignard, 1985 .

New inhibitors of iron-containing nitrile hydratases.

D. Mansuy, M. Sari, I. Artaud, 2001, Journal of biochemistry.

Human anti-mitochondria autoantibodies appearing in iproniazid-induced immunoallergic hepatitis recognize human liver monoamine oxidase B.

D. Mansuy, E. Billett, P. Dansette, 1996, Biochemical and biophysical research communications.

Diclofenac and its derivatives as tools for studying human cytochromes P450 active sites: particular efficiency and regioselectivity of P450 2Cs.

D. Mansuy, P. Dansette, M. Antignac, 1999, Biochemistry.

Nature of the complexes derived from the reaction of 1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane (DDT) with iron porphyrins: crystal and molecular structure of the vinylidene carbene complex Fe(TPP)(C:C(p-ClC6H4)2)

D. Mansuy, J. Fischer, R. Weiss, 1988 .

An intermediate-spin iron(III) porphyrin complex with a vinylidene group inserted into a iron-nitrogen bond: paramagnetic susceptibility, EPR, and Moessbauer properties

P. Gans, D. Mansuy, I. Morgenstern-Badarau, 1982 .

Iron-porphyrin-nitrene complexes: preparation, properties, and crystal structure of porphyrin-iron(III) complexes with a tosylnitrene inserted into an iron-nitrogen bond

D. Mansuy, J. Mahy, J. Fischer, 1988 .

Hydroxylation of diclofenac: an illustration of the complementary roles of biomimetic metalloporphyrin catalysts and yeasts expressing human cytochromes P450 in drug metabolism studies

D. Mansuy, P. Battioni, Virginie Mansuy-Mouries, 2000 .

Supramolecular self-assembly of a fluorinated Zn porphyrin. Molecular structure of a two-dimensional network of amine-functionalized, hexacoordinated Zn porphyrins.

D. Mansuy, K. Barkigia, J. Fajer, 2002, Chemical communications.

Metabolic stability of superoxide and hydroxyl radical adducts of a cyclic nitrone toward rat liver microsomes and cytosol: A stopped-flow ESR spectroscopy study.

J. Boucher, D. Mansuy, N. Beziere, 2010, Free radical biology & medicine.

Iron-porphyrin catalysis of the oxidative dealkylation of para-nitro-anisole and 7-ethoxycoumarin by cumylhydroperoxide: a possible model for the corresponding cytochrome P 450-dependent reactions.

D. Mansuy, P. Dansette, J. Chottard, 1980, Biochemical and biophysical research communications.

New Model Systems for Oxygenases

D. Mansuy, 1993 .

Platinum(II)-catalyzed alcohol acetylations by N-acetylimidazole

D. Mansuy, E. Mulliez, J. Chottard, 1977 .

Involvement of NO in the Endothelium-Independent Relaxing Effects of N ω-Hydroxy-l-arginine and Other Compounds Bearing a C=NOH Function in the Rat Aorta

J. Boucher, D. Mansuy, N. Callizot, 2002, Journal of Pharmacology and Experimental Therapeutics.

9-Hydroxyellipticine: inhibitory effect on skin carcinogenesis induced in Swiss mice by 7,12-dimethylbenz[a]anthracene.

D. Mansuy, P. Lesca, 1980, Chemico-biological interactions.

Bromocriptine is a strong inhibitor of brain nitric oxide synthase: possible consequences for the origin of its therapeutic effects

M. Delaforge, D. Mansuy, M. Sari, 1997, FEBS letters.

Cyclisations radicalaires XXIX cyclisation par “catalyse red-ox” de chlorures benzyliques δ-ε ethyleniques

D. Mansuy, M. Julia, B. Mansour, 1976 .

Detection of a nitric oxide synthase possibly involved in the regulation of the Rhodococcus sp R312 nitrile hydratase.

J. Boucher, D. Mansuy, M. Sari, 1998, Biochemical and biophysical research communications.

Formation of nitric oxide synthase-iron(II) nitrosoalkane complexes: severe restriction of access to the iron(II) site in the presence of tetrahydrobiopterin.

J. Boucher, D. Mansuy, M. Sari, 1998, Biochemistry.

Particular ability of cytochromes P450 3A to form inhibitory P450-iron-metabolite complexes upon metabolic oxidation of aminodrugs.

M. Delaforge, D. Mansuy, C. Bensoussan, 1995, Biochemical pharmacology.

Structure-activity relationships of a new family of steroidal aromatase inhibitors. 1. Synthesis and evaluation of a series of analogs related to 19-[(methylthio)methyl]androstenedione (RU54115).

G. Teutsch, D. Mansuy, D. Philibert, 1996, Journal of medicinal chemistry.

Mechanism of the aromatic hydroxylation of thiophene by acid-catalyzed peracid oxidation.

D. Mansuy, P. Dansette, A. Treiber, 2002, The Journal of organic chemistry.

Opposite behaviors of reactive metabolites of tienilic acid and its isomer toward liver proteins: use of specific anti-tienilic acid-protein adduct antibodies and the possible relationship with different hepatotoxic effects of the two compounds.

D. Mansuy, P. Dansette, B. Desfosses, 1999, Chemical research in toxicology.

In the presence of imidazole, iron-and manganese-porphyrins catalyse the epoxidation of alkenes by alkyl hydroperoxides

D. Mansuy, J. Renaud, P. Battioni, 1984 .

Selective Oxygenation of Hydrocarbons and Sulfoxidation of Thioethers by Dioxygen with a Mn-Porphyrin-Based Cytochrome P450 Model System Using Zn as Electron Donor.

D. Mansuy, P. Battioni, J. Bartoli, 2010 .

IRON PORPHYRIN-NITRENE COMPLEXES: PREPARATION FROM 1,1-DIALKYLHYDRAZINES. ELECTRONIC STRUCTURE FROM NMR, MOESSBAUER, AND MAGNETIC SUSCEPTIBILITY STUDIES AND CRYSTAL STRUCTURE OF THE (TETRAKIS(P-CHLOROPHENYL)PORPHYRINATO)((2,2,6,6-TETR

P. Gans, D. Mansuy, J. Mahy, 1984 .

Reaction of a carbon equivalent of iodosylbenzene with iron-porphyrins: a ready access to N-alkylporphyrin complexes involving five-membered [cyclic] Fe-O-C-C-N metallocycles

D. Mansuy, J. Fischer, I. Akhrem, 1986 .

Reaction of a carbon analog of iodosylbenzene with iron porphyrins: isolation and x-ray structure of an iron(II) complex with O-C-C moieties inserted between two trans iron-nitrogen bonds

D. Mansuy, J. Fischer, I. Akhrem, 1984 .

A new route to thiocarbonyliron complexes: preparation of FeII[porphyrin][C(Cl)SR] carbene complexes and their conversion into FeII[porphyrin][CS] complexes

D. Mansuy, J. Chottard, J. Battioni, 1982 .

Reaction of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT) with iron(II) porphyrins. Isolation of the vinylidene carbene complex, tetraphenylporphyriniron(II) (C:C(p-Cl-C6H4)2)

D. Mansuy, J. Chottard, M. Lange, 1978 .

Synthesis and effects on arginase and nitric oxide synthase of two novel analogues of Nω-hydroxyarginine, Nω-hydroxyindospicine and p-hydroxyamidinophenylalanine

J. Boucher, S. Vadon, D. Mansuy, 1996 .

Very general formation of tetrahydropterin cation radicals during reaction of iron porphyrins with tetrahydropterins: model for the corresponding NO-synthase reaction.

J. Boucher, D. Mansuy, Y. Frapart, 2004, Chemical communications.

Cytochrome P450 catalyzes the oxidation of N omega-hydroxy-L-arginine by NADPH and O2 to nitric oxide and citrulline.

J. Boucher, A. Genet, S. Vadon, 1992, Biochemical and Biophysical Research Communications - BBRC.

Oxidation of tienilic acid by human yeast-expressed cytochromes P-450 2C8, 2C9, 2C18 and 2C19. Evidence that this drug is a mechanism-based inhibitor specific for cytochrome P-450 2C9.

D. Mansuy, J. Goldstein, P. Dansette, 1996, European journal of biochemistry.

Cytochromes P450 and drug toxicity

D. Mansuy, 1995, Clinical Reviews in Allergy and Immunology.

Formation of nitric oxide by cytochrome P450-catalyzed oxidation of aromatic amidoximes.

J. Boucher, M. Delaforge, D. Mansuy, 1992, Biochemical and Biophysical Research Communications - BBRC.

Suicidal inactivation of iron-porphyrin catalysts during 1-alkene oxidation. Isolation of a new type of N-alkylporphyrin

D. Mansuy, I. Artaud, J. Girault, 1987 .

Suicidal Inactivation of Iron Porphyrin Catalysts During Alk‐1‐ene Oxidation: Isolation of a New Type of N‐Alkylporphyrins.

D. Mansuy, I. Artaud, J. Girault, 1987 .

5-[4-(benzyloxy)phenyl]-1,3,4-oxadiazol-2(3H)-one derivatives and related analogues: new reversible, highly potent, and selective monamine oxidase type B inhibitors.

D. Mansuy, C. Burstein, S. Gueddari, 1993, Journal of medicinal chemistry.

A heme model study of carbon tetrachloride metabolism: mechanisms of phosgene and carbon dioxide formation.

D. Mansuy, M. Fontecave, J. Chottard, 1980, Biochemical and biophysical research communications.

Expression in yeast of three allelic cDNAs coding for human liver P-450 3A4. Different stabilities, binding properties and catalytic activities of the yeast-produced enzymes.

D. Mansuy, J. Renaud, D. Pompon, 1993, European journal of biochemistry.

Ellipticines as potent inhibitors of drug metabolism. Protective effect against chemical mutagenesis and carcinogenesis

D. Mansuy, C. Paoletti, P. Lesca, 1978 .

Rearrangement of vobasine to ervatamine-type alkaloids catalyzed by liver microsomes

D. Mansuy, C. Thal, P. Potier, 1981 .

Inhibition by pesticides of the DJ-1/Park7 protein related to Parkinson disease.

X. Coumoul, R. Barouki, D. Mansuy, 2023, Toxicology.

Metalloporphyrinosilicas: A New Class of Hybrid Organic-Inorganic Materials Acting as Selective Biomimetic Oxidation Catalysts

D. Mansuy, M. Louloudi, G. Spyroulias, 1997 .

Structure of meso-tetraaryl-β-octahalogeno-porphyrins : a semi-empirical quantum mechanical investigation

D. Mansuy, C. Giessner-Prettre, P. Battioni, 1992 .

Use of isotopes and LC-MS-ESI-TOF for mechanistic studies of tienilic acid metabolic activation.

D. Mansuy, M. Belghazi, P. Dansette, 2001, Advances in experimental medicine and biology.

Inhibition by ticlopidine and its derivatives of human liver cytochrome p450. Mechanism-based inactivation of CYP 2C19 by ticlopidine.

D. Mansuy, P. Dansette, S. Dijols, 2001, Advances in experimental medicine and biology.

Strong inhibition of neuronal nitric oxide synthase by the calmodulin antagonist and anti-estrogen drug tamoxifen.

J. Boucher, M. Delaforge, D. Mansuy, 1997, Biochemical pharmacology.

Unprecedented ipso aromatic nucleophilic substitution upon oxidative decarboxylation of tris(p-carboxyltetrathiaaryl)methyl (TAM) radicals: a new access to diversely substituted TAM radicals.

T. Prangé, J. Boucher, D. Mansuy, 2011, Chemical communications.

Oxidation of tris-(p-carboxyltetrathiaaryl)methyl radical EPR probes: evidence for their oxidative decarboxylation and molecular origin of their specific ability to react with O2*-.

J. Boucher, D. Mansuy, G. Bertho, 2009, Chemical communications.

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

D. Mansuy, A. Vessières, G. Jaouen, 2015, ChemMedChem.

Resonance Raman spectra of iron tetraphenylporphyrin complexes: characterization of structure and bonding sensitive bands

D. Mansuy, P. Battioni, G. Chottard, 1981 .

The stimulatory effects of asbestos on NADPH-dependent lipid peroxidation in rat liver microsomes.

D. Mansuy, M. Fontecave, M. Jaouen, 1987, The Biochemical journal.

Active site topology of artificial peroxidase-like hemoproteins based on antibodies constructed from a specifically designed ortho-carboxy-substituted tetraarylporphyrin.

S. Benkovic, D. Mansuy, M. Sari, 1998, European journal of biochemistry.

Sulfenic acids as reactive intermediates in xenobiotic metabolism.

D. Mansuy, P. Dansette, 2011, Archives of biochemistry and biophysics.

Cationic porphyrin-DNA interactions: importance of the number and position of the charges.

D. Mansuy, J. Le Pecq, D. Dupré, 1988, Biochemical pharmacology.