M. Uhler

发表

Cyclic AMP-dependent protein kinase decreases GABAA receptor current in mouse spinal neurons

N. Porter, R. Macdonald, R. Twyman, 1990, Neuron.

Incorporating spatial dependence into a multicellular tumor spheroid growth model

T. Jackson, M. Uhler, R. Gilgenbach, 2005 .

Effect of pulsed, high-power radiofrequency radiation on electroporation of mammalian cells

M. Uhler, R. Gilgenbach, D. Jordan, 2004, IEEE Transactions on Plasma Science.

Implications of a simple mathematical model to cancer cell population dynamics

M. Uhler, R. Gilgenbach, A. Garner, 2006, Cell proliferation.

Microarray transfection analysis of conserved genomic sequences from three immediate early genes.

M. Uhler, Xiaomei Ren, 2009, Genomics.

Molecular Cloning and Expression of Mammalian Peroxisomaltrans-2-Enoyl-coenzyme A Reductase cDNAs*

A. Das, M. Uhler, A. Das, 2000, The Journal of Biological Chemistry.

Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate-sensitive chromaffin cells.

M. Uhler, R. Holz, P. Wick, 1993, The Journal of biological chemistry.

Glutamic acid 203 of the cAMP-dependent protein kinase catalytic subunit participates in the inhibition by two isoforms of the protein kinase inhibitor.

M. Uhler, E. Reimann, E. Baude, 1994, The Journal of biological chemistry.

Characterization of PKIγ, a Novel Isoform of the Protein Kinase Inhibitor of cAMP-dependent Protein Kinase*

M. Uhler, S. P. Collins, Michael D. Uhler, 1997, The Journal of Biological Chemistry.

Molecular cloning of a gene encoding the histamine H2 receptor.

M. Uhler, C. Logsdon, T. Yamada, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides.

M. Uhler, G. McKnight, G. Cadd, 1990, The Journal of biological chemistry.

Uptake and release of naphthalene and its metabolites in skin and epidermal mucus of salmonids.

M. Uhler, U. Varanasi, S. Stranahan, 1978, Toxicology and applied pharmacology.

The mouse genome contains two nonallelic pro-opiomelanocortin genes.

P. D’Eustachio, M. Uhler, E. Herbert, 1983, The Journal of biological chemistry.

Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

R. G. Allen, R. Gross, M. Uhler, 1994, Molecular endocrinology.

Regulation of opioid gene expression

N. Birnberg, M. Uhler, M. Comb, 1983, Peptides.

Invertebrate Learning and Memory

Carl W. Cotman, Bernard W. Agranoff, Michael D. Uhler, 1999 .

Application of molecular genetic techniques to the cAMP-dependent protein kinase system.

M. Uhler, G. McKnight, C. Clegg, 1988, Methods in enzymology.

HIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.

M. Uhler, Huabing Zhang, S. Ramakrishnan, 2016, Cell metabolism.

Phosphatidylinositol 3‐kinase and Akt effectors mediate insulin‐like growth factor‐I neuroprotection in dorsal root ganglia neurons

M. Uhler, E. Feldman, G. Leinninger, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Evidence for two additional isoforms of the endogenous protein kinase inhibitor of cAMP-dependent protein kinase in mouse.

M. Uhler, M. Scarpetta, 1993, The Journal of biological chemistry.

Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain.

M. Uhler, 1993, The Journal of biological chemistry.

Characterization of PKI g , a Novel Isoform of the Protein Kinase Inhibitor of cAMP-dependent Protein Kinase *

M. Uhler, S. P. Collins, 1997 .

Isolation and characterization of cDNA clones for an inhibitor protein of cAMP-dependent protein kinase.

M. Uhler, S. Olsen, 1991, The Journal of biological chemistry.

Nerve growth factor inhibits PC12 cell PDE 2 phosphodiesterase activity and increases PDE 2 binding to phosphoproteins

D. Juilfs, M. Uhler, J. Bentley, 2001, Journal of neurochemistry.

Sertoli cells are the primary site of prodynorphin gene expression in rat testis: regulation of mRNA and secreted peptide levels by cyclic adenosine 3' ,5'-monophosphate analogs in cultured cells.

H. Akil, M. Uhler, R. Day, 1990, Molecular endocrinology.

The Proopiomelanocortin Genes

M. Uhler, E. Herbert, 1987 .

Deficient Gene Expression in Protein Kinase Inhibitor α Null Mutant Mice

M. Uhler, R. Idzerda, G. McKnight, 2000, Molecular and Cellular Biology.

Deﬁcient Gene Expression in Protein Kinase Inhibitor a Null Mutant Mice

M. Uhler, R. Idzerda, G. McKnight, 2000 .

Regulation of the human enkephalin promoter by two isoforms of the catalytic subunit of cyclic adenosine 3',5'-monophosphate-dependent protein kinase.

M. Uhler, A. Seasholtz, J. Huggenvik, 1991, Molecular endocrinology.

Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents.

R. Gross, R. Macdonald, M. Uhler, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Investigation by transient transfection of the effects on regulated exocytosis of Rab3a.

M. Uhler, R. Holz, R. Senter, 1995, Methods in enzymology.

Transcriptional Regulatory Events Initiated by Ascl1 and Neurog2 During Neuronal Differentiation of P19 Embryonic Carcinoma Cells

Robert C. Thompson, M. Uhler, Shweta Gupta, 2015, Journal of Molecular Neuroscience.

The cyclic AMP‐dependent protein kinase catalytic subunit selectively enhances calcium currents in rat nodose neurones.

R. Groß, M. Uhler, R. L. Macdonald, 1990, The Journal of physiology.

A Transforming Growth Factor β-Induced Smad3/Smad4 Complex Directly Activates Protein Kinase A

M. Uhler, C. Logsdon, D. Simeone, 2004, Molecular and Cellular Biology.

Generation of diversity and evolution of opioid peptides.

M. Uhler, M. Comb, E. Herbert, 1983, Cold Spring Harbor symposia on quantitative biology.

Induction of alkaline phosphatase in mouse L cells by overexpression of the catalytic subunit of cAMP-dependent protein kinase.

M. Uhler, N. A. Brown, R. E. Stofko, 1990, The Journal of biological chemistry.

gRICH68 and gRICH70 Are 2′,3′-Cyclic-nucleotide 3′-Phosphodiesterases Induced during Goldfish Optic Nerve Regeneration*

B. Agranoff, M. Uhler, R. P. Ballestero, 1997, The Journal of Biological Chemistry.

Transcriptional Regulatory Events Initiated by Ascl1 and Neurog2 During Neuronal Differentiation of P19 Embryonic Carcinoma Cells

Robert C. Thompson, M. Uhler, Shweta Gupta, 2014, Journal of Molecular Neuroscience.

Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.

M. Uhler, G. McKnight, J. Chrivia, 1988, The Journal of biological chemistry.

Ascl1‐induced neuronal differentiation of P19 cells requires expression of a specific inhibitor protein of cyclic AMP‐dependent protein kinase

M. Uhler, D. Turner, R. Thompson, 2012, Journal of neurochemistry.

The mouse Prkacn2 gene encoding protein kinase a inhibitor 2 is located on proximal chromosome 10

M. Meisler, M. Uhler, M. Scarpetta, 1996, Mammalian Genome.

The Major Catalytic Subunit Isoforms of cAMP-dependent Protein Kinase Have Distinct Biochemical Properties in Vitro and in Vivo*

M. Uhler, E. Baude, D. Gamm, 1996, The Journal of Biological Chemistry.

The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain.

E. Krebs, D. Helfman, J. Scott, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Direct transcriptional induction of Gadd45γ by Ascl1 during neuronal differentiation

M. Uhler, D. Turner, G. Murphy, 2010, Molecular and Cellular Neuroscience.

microRNA-mRNA Profile of Skeletal Muscle Differentiation and Relevance to Congenital Myotonic Dystrophy

M. Uhler, S. Morton, Manhong Dai, 2021, International journal of molecular sciences.

Expression of cDNAs for two isoforms of the catalytic subunit of cAMP-dependent protein kinase.

M. Uhler, G. McKnight, 1987, The Journal of biological chemistry.

Negative regulation of Yap during neuronal differentiation.

Robert C. Thompson, M. Uhler, D. Turner, 2012, Developmental biology.

Expression of a cDNA for a neuronal calcium channel alpha 1 subunit enhances secretion from adrenal chromaffin cells.

M. Uhler, R. Holz, W. Ma, 1992, The Journal of biological chemistry.

A novel fluorescent transcriptional reporter for cell-based microarray assays.

M. Uhler, Tanya M. Redmond, 2011, Methods in molecular biology.

Microarray Transfection Analysis of Transcriptional Regulation by cAMP-dependent Protein Kinase*

M. Uhler, S. Atkins, Xiaomei Ren, 2004, Molecular & Cellular Proteomics.

Analysis of the cAMP-dependent protein kinase system using molecular genetic approaches.

M. Uhler, G. McKnight, C. Clegg, 1988, Recent progress in hormone research.

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

M. Uhler, G. McKnight, J. Chrivia, 1986, The Journal of biological chemistry.

Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase.

E. Krebs, M. Uhler, G. McKnight, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Complete amino acid sequence of mouse pro-opiomelanocortin derived from the nucleotide sequence of pro-opiomelanocortin cDNA.

M. Uhler, E. Herbert, 1983, The Journal of biological chemistry.

Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase.

F. Talamantes, M. Uhler, J. Nielsen, 1992, The Journal of biological chemistry.

LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo.

M. Uhler, D. Gamm, J. Reoma, 2000, The Biochemical journal.

Regulation of the Ku70-Bax complex in Cells By Manila Hada A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy

M. Uhler, J. Iñiguez-Lluhí, P. Andrews, 2015 .

Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element.

M. Uhler, J. Leiden, J M Leiden, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Fibroblast growth factor 2 regulates activity and gene expression of human post‐mitotic excitatory neurons

H. Akil, J. Parent, S. Watson, 2018, Journal of neurochemistry.

Species-specific differences in NPC1 protein trafficking govern therapeutic response in Niemann-Pick type C disease

M. Uhler, A. Lieberman, S. Cologna, 2022, JCI insight.

Inhibition of protein kinase-A by overexpression of the cloned human protein kinase inhibitor.

M. Uhler, S. Olsen, 1991, Molecular endocrinology.

Cloning of CDP‐Diacylglycerol Synthase from a Human Neuronal Cell Line

B. Agranoff, M. Uhler, A. Heacock, 1996, Journal of neurochemistry.

Protein Kinase A Modulates Transforming Growth Factor-β Signaling through a Direct Interaction with Smad4 Protein*

M. Uhler, Lidong Wang, D. Simeone, 2013, The Journal of Biological Chemistry.

Rapid Generation of Human Genetic Loss-of-Function iPSC Lines by Simultaneous Reprogramming and Gene Editing

J. Parent, M. Uhler, Andrew M. Tidball, 2017, Stem cell reports.

A mutation in the catalytic subunit of protein kinase A prevents myristylation but does not inhibit biological activity.

M. Uhler, G. McKnight, C. Clegg, 1989, The Journal of biological chemistry.

Vascular endothelial cells express isoforms of protein kinase A inhibitor.

M. Uhler, H. Lum, Hazel Lum, 2002, American journal of physiology. Cell physiology.

Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique

M. Uhler, R. Macdonald, TP Angelotti, 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Autoinhibition and Isoform-specific Dominant Negative Inhibition of the Type II cGMP-dependent Protein Kinase*

M. Uhler, R. Ahmed, Michael Begley, 2002, The Journal of Biological Chemistry.

Localization of cGMP-dependent protein kinase isoforms in mouse eye.

M. Uhler, D. Gamm, P. Raymond, 2000, Investigative ophthalmology & visual science.

Molecular Cloning and Expression of cDNA Encoding Rat Brain Cytosolic Acyl-Coenzyme A Thioester Hydrolase (*)

M. Uhler, C. Broustas, A. Hajra, 1996, The Journal of Biological Chemistry.

The reduction of neuronal calcium currents by ATP-γ-S is mediated a G protein and occurs independently of cyclic AMP-dependent protein kinase

R. Gross, R. Macdonald, M. Uhler, 1990, Brain Research.

Amino Acids in Proteins

B. Agranoff, M. Uhler, G. Siegel, 1999 .

The reduction of neuronal calcium currents by ATP-gamma-S is mediated by a G protein and occurs independently of cyclic AMP-dependent protein kinase.

R. Gross, R. Macdonald, M. Uhler, 1990, Brain research.

A cGMP‐dependent protein kinase is implicated in wild‐type motility in C. elegans

M. Uhler, E. Baude, Suk-Won Jin, 2001, Journal of neurochemistry.

Phosphorylation-dependent Inhibition of Protein Phosphatase-1 by G-substrate

M. Uhler, A. Depaoli-Roach, D. Gamm, 1999, The Journal of Biological Chemistry.

The Type II Isoform of cGMP-dependent Protein Kinase Is Dimeric and Possesses Regulatory and Catalytic Properties Distinct from the Type I Isoforms (*)

M. Uhler, J. Corbin, D. Gamm, 1995, The Journal of Biological Chemistry.

Enhancement of recombinant gamma-aminobutyric acid type A receptor currents by chronic activation of cAMP-dependent protein kinase.

R. Macdonald, M. Uhler, T. Angelotti, 1993, Molecular pharmacology.

Comparison of fura-2 imaging and electrophysiological analysis of murine calcium channel alpha 1 subunits coexpressed with novel beta 2 subunit isoforms.

R. Macdonald, M. Uhler, K. Kelly, 1995, Molecular pharmacology.

Differential expression of mRNAs for protein kinase inhibitor isoforms in mouse brain.

M. Uhler, R. P. Ballestero, A. Seasholtz, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Cellular concentrations of protein kinase A modulate prostaglandin and cAMP induction of alkaline phosphatase.

M. Uhler, A. Abou‐Chebl, 1992, Journal of Biological Chemistry.

Biosynthesis of polyprotein precursors to regulatory peptides

M. Uhler, E. Herbert, 1982, Cell.

Cyclic AMP- and Cyclic GMP-dependent Protein Kinases Differ in Their Regulation of Cyclic AMP Response Element-dependent Gene Transcription*

M. Uhler, S. P. Collins, Michael D. Uhler, 1999, The Journal of Biological Chemistry.

Cloning and Characterization of zRICH, a 2′,3′‐Cyclic‐Nucleotide 3′‐Phosphodiesterase Induced During Zebrafish Optic Nerve Regeneration

B. Agranoff, M. Uhler, R. P. Ballestero, 1999, Journal of neurochemistry.

Isolation of cDNA clones encoding RICH: a protein induced during goldfish optic nerve regeneration with homology to mammalian 2',3'-cyclic-nucleotide 3'-phosphodiesterases.

B. Agranoff, M. Uhler, R. P. Ballestero, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Isoform-specific Differences in the Potencies of Murine Protein Kinase Inhibitors Are Due to Nonconserved Amino-terminal Residues (*)

M. Uhler, D. Gamm, Michael D. Uhler, 1995, The Journal of Biological Chemistry.