M. Reith

A. Lajtha, H. Sershen, M. Reith, 1989, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

The role of serotonin in the actions of psychostimulants: molecular and pharmacological analyses

M. Reith, C. Bradberry, K. Cunningham, 1995, Behavioural Brain Research.

Locomotor effects of cocaine, cocaine congeners, and local anesthetics in mice

A. Lajtha, M. Reith, B. E. Meisler, 1985, Pharmacology, Biochemistry and Behavior.

The pharmacological relevance of the cocaine binding site in mouse brain

A. Lajtha, H. Sershen, M. Reith, 1980, Neuropharmacology.

Sertraline and cocaine-induced locomotion in mice

M. Reith, C. Fischette, 1991, Psychopharmacology.

Presence of the toxic metabolite N-hydroxy-norcocaine in brain and liver of the mouse.

A. Lajtha, M. Benuck, M. Reith, 1988, Biochemical pharmacology.

Effects of diet and insulin on dopamine transporter activity and expression in rat caudate‐putamen, nucleus accumbens, and midbrain

M. Reith, J. Zhen, Tamara Antonio, 2017, Journal of neurochemistry.

Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward

Paul Witkovsky, M. Rice, P. Witkovsky, 2015, Nature Communications.

Dopamine transporter deficiency syndrome: phenotypic spectrum from infancy to adulthood

E. Puffenberger, K. Strauss, M. Reith, 2014, Brain : a journal of neurology.

Is Na+ required for the binding of dopamine, amphetamine, tyramine, and octopamine to the human dopamine transporter?

M. Reith, Li-Bin Li, Xiao-Nan Cui, 2002, Naunyn-Schmiedeberg's Archives of Pharmacology.

Extracellular dopamine, norepinephrine, and serotonin in the ventral tegmental area and nucleus accumbens of freely moving rats during intracerebral dialysis following systemic administration of cocaine and other uptake blockers

M. Reith, M. E. A. Reith, Ming-Ya Li, 1997, Psychopharmacology.

Uptake of [3H]serotonin into plasma membrane vesicles from mouse cerebral cortex.

M. Reith, C. A. O'Reilly, 1988, The Journal of biological chemistry.

Nitric oxide scavenger carboxy-PTIO potentiates the inhibition of dopamine uptake by nitric oxide donors.

M. Reith, B. Cao, 2002, European journal of pharmacology.

Effects of caffeine on monoaminergic systems in mouse brain.

A. Lajtha, H. Sershen, M. Reith, 1987, Acta biochimica et biophysica Hungarica.

Monoamine Interactions Measured by Microdialysis in the Ventral Tegmental Area of Rats Treated Systemically with (±)‐8‐Hydroxy‐2‐(Di‐n‐Propylamino)tetralin

M. Reith, Nian‐Hang Chen, 1995, Journal of neurochemistry.

Separation and determination of sertraline and its metabolite, desmethylsertraline, in mouse cerebral cortex by reversed-phase high-performance liquid chromatography.

H. L. Wiener, M. Reith, H. Kramer, 1990, Journal of chromatography.

Effect of quinine on autoreceptor-regulated serotonin release in the rat hippocampus.

M. Reith, M. -. Li, 1997, European journal of pharmacology.

Nicotine-induced changes in the metabolism of specific brain proteins

H. Sershen, M. Reith, D. Dunlop, 1987, Neurochemical Research.

Enhanced accumbal dopamine release following 5-HT2A receptor stimulation in rats pretreated with intermittent cocaine

M. Reith, Q. Yan, S. Yan, 2000, Brain Research.

Continuous cocaine treatment and monoamine transmission measured by microdialysis in the rat ventral tegmental area

M. Reith, Ming‐Ya Li, 1998, Addiction biology.

Neurotransmitter Transporters: "Structure, Function, And Regulation"

M. Reith, Maarten E. A. Reith, 2010 .

Preferential Increases in Nucleus Accumbens Dopamine after Systemic Cocaine Administration Are Caused by Unique Characteristics of Dopamine Neurotransmission

P. Garris, M. Kuhar, M. Reith, 2000, The Journal of Neuroscience.

Comparison of [3H]nicotine and [3H]acetylcholine binding in mouse brain: regional distribution.

A. Lajtha, H. Sershen, A. Hashim, 1985, Research communications in chemical pathology and pharmacology.

Metaphit amplifies long-term potentiation (LTP) in the mouse hippocampus.

M. Reith, M. V. Hogan, A. Wieraszko, 1994, Life sciences.

Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice.

A. Lajtha, M. Reith, B. Zlokovic, 1989, European journal of pharmacology.

The selective dopamine uptake inhibitor, D-84, suppresses cocaine self-administration, but does not occasion cocaine-like levels of generalization.

M. Reith, Aloke K. Dutta, P. Beardsley, 2010, European journal of pharmacology.

D-578, an orally active triple monoamine reuptake inhibitor, displays antidepressant and anti-PTSD effects in rats.

M. Reith, S. Perrine, Liping Xu, 2019, European journal of pharmacology.

Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules.

M. Reith, X. Fei, P. Beardsley, 2002, Journal of medicinal chemistry.

Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.

M. Reith, A. Dutta, X. Fei, 2001, Journal of medicinal chemistry.

Structure-Activity Relationship Studies of Novel 4-(2-(Bis(4- fluorophenyl)methoxy)ethyl)-1-(3-phenylpropyl)piperidine Analogues: Synthesis and Biological Evaluation at the Dopamine and Serotonin Transporter Sites.

M. Reith, A. Dutta, Cen Xu, 1996 .

High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.

C. George, M. Reith, P. Beardsley, 2003, Journal of medicinal chemistry.

Effect of cocaine and cocaine congeners on veratridine‐induced depolarization in mouse cerebrocortical synaptoneurosomes

A. Lajtha, M. Reith, I. Zimanyi, 1989, Journal of neuroscience research.

[3H]WIN 35,428 binding to the dopamine uptake carrier. I. Effect of tonicity and buffer composition

M. Reith, L. L. Coffey, 1994, Journal of Neuroscience Methods.

Bivalent phenethylamines as novel dopamine transporter inhibitors: evidence for multiple substrate‐binding sites in a single transporter

M. Reith, Kyle C. Schmitt, S. Mamidyala, 2010, Journal of neurochemistry.

Nitric oxide inhibits uptake of dopamine and N‐methyl‐4‐phenylpyridinium (MPP+) but not release of MPP+ in rat C6 glioma cells expressing human dopamine transporter

M. Reith, B. Cao, 2002, British journal of pharmacology.

Overview of the structure and function of the dopamine transporter and its protein interactions

M. Reith, S. Kortagere, B. Nepal, 2023, Frontiers in Physiology.

LeuT-Desipramine Structure Reveals How Antidepressants Block Neurotransmitter Reuptake

Da-Neng Wang, M. Reith, N. Karpowich, 2007, Science.

Novel Potent Dopamine-Norepinephrine and Triple Reuptake Uptake Inhibitors Based on Asymmetric Pyran Template and Their Molecular Interactions with Monoamine Transporters.

M. Reith, S. Kortagere, Aloke K. Dutta, 2021, ACS chemical neuroscience.

Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities

M. Reith, J. Zhen, Shu-Yuan Cheng, 2015, Journal of neurochemistry.

Structural Exploration of (3S,6S)‐6‐Benzhydryl‐N‐benzyltetrahydro‐2H‐pyran‐3‐amine Analogues: Identification of Potent Triple Monoamine Reuptake Inhibitors as Potential Antidepressants

M. Reith, J. Zhen, Aloke K. Dutta, 2012, ChemMedChem.

Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.

M. Reith, J. Zhen, Aloke K. Dutta, 2011, Journal of medicinal chemistry.

Interrelation of dopamine transporter oligomerization and surface presence as studied with mutant transporter proteins and amphetamine

M. Reith, Shu-Yuan Cheng, N. Chen, 2010, Journal of neurochemistry.

Substrate-Induced Trafficking of the Dopamine Transporter in Heterologously Expressing Cells and in Rat Striatal Synaptosomal Preparations

M. Reith, L. Chi, 2003, Journal of Pharmacology and Experimental Therapeutics.

5-HT3 receptor antagonists attenuate cocaine-induced locomotion in mice.

M. Reith, Maarten E. A. Reith, 1990, European journal of pharmacology.

Metaphit prevents locomotor activation by dopamine uptake blockers and increases homovanillic acid

H. Sershen, M. Reith, K. Rice, 1987 .

Determination of radioligand specific activity using competition binding assays.

H. L. Wiener, M. Reith, 1992, Analytical biochemistry.

Incorporation of [3H] leucine into brain stem protein fractions: the effect of a behaviorally active, N-terminal fragment of ACTH in hypophysectomized rats.

M. Reith, W. Gispen, P. Schotman, 1975, Neurobiology.

Chronic food restriction and dopamine transporter function in rat striatum

M. Reith, J. Zhen, K. Carr, 2006, Brain Research.

Complex interaction of cocaine with the dopamine uptake carrier.

R. Roth, M. Reith, J. Elsworth, 1990, European journal of pharmacology.

Dual incorporation of photoaffinity ligands on dopamine transporters implicates proximity of labeled domains.

M. Reith, R. Vaughan, J. D. Gaffaney, 2001, Molecular pharmacology.

A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: binding activity at D2 and D3 receptors.

M. Reith, X. Fei, A. Dutta, 2002, Bioorganic & medicinal chemistry letters.

Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane potential

M. Reith, N. Chen, 2004, Journal of neurochemistry.

Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template.

M. Reith, Aloke K. Dutta, Tamara Antonio, 2015, Bioorganic & medicinal chemistry.

Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine

M. Reith, J. Zhen, N. Chen, 2004, Journal of neurochemistry.

Effect of nicotine and amphetamine on the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice

A. Lajtha, H. Sershen, A. Hashim, 1986, Neuropharmacology.

Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.

C. George, M. Reith, Rohit Kolhatkar, 2003, Journal of medicinal chemistry.

Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area.

M. Reith, P. Jobe, J. Dailey, 1996, European journal of pharmacology.

Novel Structure–Function Information on Biogenic Amine Transporters Revealed by Site-Directed Mutagenesis and Alkylation

M. Reith, 2013, Neurochemical Research.

[3H]WIN 35,428 binding to the dopamine uptake carrier. II. Effect of membrane fractionation procedure and freezing

M. Reith, L. L. Coffey, 1994, Journal of Neuroscience Methods.

Metaphit prevents locomotor activation induced by various psychostimulants and interferes with the dopaminergic system in mice

H. Sershen, M. Reith, K. Rice, 1988, Neuropharmacology.

Metaphit, a receptor acylator, inactivates cocaine binding sites in striatum and antagonizes cocaine-induced locomotor stimulation in rodents

M. Reith, K. Rice, P. Berger, 1986, Neuropharmacology.

Locomotor depression in mice by norcocaine does not involve central α2-adrenergic or presynaptic dopamine receptors

A. Lajtha, M. Reith, 1986, Pharmacology Biochemistry and Behavior.

Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.

J. Deschamps, M. Reith, Rohit Kolhatkar, 2004, Journal of medicinal chemistry.

SKF‐83566, a D1‐dopamine receptor antagonist, inhibits the dopamine transporter

M. Rice, M. Reith, Federica Sarti, 2011, Journal of neurochemistry.

Effect of systemic ethanol on basal and stimulated glutamate releases in the nucleus accumbens of freely moving Sprague–Dawley rats: a microdialysis study

M. Reith, P. Jobe, Q. Yan, 1998, Neuroscience Letters.

Extracellular Dopamine, Norepinephrine, and Serotonin in the Nucleus Accumbens of Freely Moving Rats During Intracerebral Dialysis with Cocaine and Other Monoamine Uptake Blockers

M. Reith, M Y Li, Q S Yan, 1996, Journal of neurochemistry.

Selective activation of Dopamine D3 receptors and norepinephrine transporter blockade enhances sustained attention

B. Waterhouse, J. Shumsky, M. Reith, 2019, Neuropharmacology.

Dopamine D2/D3 Agonists with Potent Iron Chelation, Antioxidant and Neuroprotective Properties: Potential Implication in Symptomatic and Neuroprotective Treatment of Parkinson’s Disease

J. Andersen, M. Reith, Aloke K. Dutta, 2011, ChemMedChem.

In vivo microdialysis for measurement of extracellular monoamine levels following inhibition of monoamine transporters.

M. Reith, N. Chen, 1998, Methods in enzymology.

Role of Axonal and Somatodendritic Monoamine Transporters in Action of Uptake Blockers

M. Reith, N. Chen, 1997 .

Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: a microdialysis study in freely moving rats.

M. Reith, N. Chen, 1994, Journal of Pharmacology and Experimental Therapeutics.

Correction: The Atypical Stimulant and Nootropic Modafinil Interacts with the Dopamine Transporter in a Different Manner than Classical Cocaine-Like Inhibitors

M. Reith, Kyle C. Schmitt, 2012, PLoS ONE.

Synthesis and preliminary characterization of a high‐affinity novel radioligand for the dopamine transporter

M. Reith, Aloke K. Dutta, B. Madras, 2001, Synapse.

Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.

M. Reith, A. Dutta, L. L. Coffey, 1997, Journal of medicinal chemistry.

Rational design and synthesis of novel 2,5-disubstituted cis- and trans-piperidine derivatives exhibiting differential activity for the dopamine transporter.

M. Reith, A. Dutta, M. C. Davis, 2001, Bioorganic & medicinal chemistry letters.

Highly Selective, Novel Analogues of 4-(2-(Diphenylmethoxy)ethyl)-1- benzylpiperidine for the Dopamine Transporter: Effect of Different Aromatic Substitutions on Their Affinity and Selectivity.

M. Reith, Aloke K. Dutta, L. L. Coffey, 1997 .

Structure−Activity Relationship Studies of 4-[2-(Diphenylmethoxy)ethyl]-1-benzylpiperidine Derivatives and Their N-Analogues: Evaluation of Behavioral Activity of O- and N-Analogues and Their Binding to Monoamine Transporters

M. Reith, Aloke K. Dutta, X. Fei, 2001 .

Potent and selective ligands for the dopamine transporter (DAT): structure-activity relationship studies of novel 4-[2-(diphenylmethoxy)ethyl]-1-(3-phenylpropyl)piperidine analogues.

M. Reith, A. Dutta, L. L. Coffey, 1998, Journal of medicinal chemistry.

Inhibition by cocaine of inositol phospholipid hydrolysis induced by the sodium channel activator batrachotoxin in mouse cerebral cortex.

M. Reith, S. S. Kim, 1988, Biochemical pharmacology.

Pharmacological and Behavioral Characterization of D-473, an Orally Active Triple Reuptake Inhibitor Targeting Dopamine, Serotonin and Norepinephrine Transporters

M. Reith, O. Mabrouk, Aloke K. Dutta, 2014, PloS one.

Dopamine agonists in treatment of Parkinson's disease: an overview

M. Reith, Aloke K. Dutta, Dan Luo, 2020 .

Pharmacological profile of radioligand binding to the norepinephrine transporter: instances of poor indication of functional activity

M. Reith, Aloke K. Dutta, Lijuan C. Wang, 2005, Journal of Neuroscience Methods.

Binding of [3H]Imipramine to Mouse Cerebrocortical Membranes and to Glass Fiber Filters

M. Reith, 1986, Journal of neurochemistry.

Synthesis and evaluation of C9 alkoxy analogues of (-)-stepholidine as dopamine receptor ligands.

Satishkumar V. Gadhiya, I. Alberts, W. Harding, 2017, European journal of medicinal chemistry.

Use of radiolabeled antagonist assays for assessing agonism at D2 and D3 dopamine receptors: Comparison with functional GTPγS assays

K. Neve, M. Reith, J. Zhen, 2015, Journal of Neuroscience Methods.

Amine Transporters

M. Reith, 2020, eLS.

On the interaction between nicotine and cycloheximide

A. Lajtha, H. Sershen, M. Reith, 1982, Brain Research.

Cocaine receptors on monoamine transporters and sodium channels.

M. Reith, 1988, NIDA research monograph.

Effect of cigarette smoke on protein synthesis in brain and liver

A. Lajtha, H. Sershen, M. Reith, 1981, Neuropharmacology.

Modeling of the Interaction of Na+ and K+ with the Binding of the Cocaine Analogue 3β‐(4‐[125I]Iodophenyl)tropane‐2β‐Carboxylic Acid Isopropyl Ester to the Dopamine Transporter

M. Reith, N. Chen, J. Ding, 1997, Journal of neurochemistry.

Pituitary peptides and brain protein synthesis

M. Reith, W. Gispen, P. Schotman, 1977 .

Efficacy of Hybrid Tetrahydrobenzo[d]thiazole Based Aryl Piperazines D-264 and D-301 at D2 and D3 Receptors

D. Grandy, D. Selley, M. Reith, 2015, Neurochemical Research.