D. Chuang

L. Tsai, D. Chuang, P. Leeds, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Multiple roles of HDAC inhibition in neurodegenerative conditions

Yan Leng, Hyeon-Ju Kim, Z. Marinova, 2009, Trends in Neurosciences.

The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain

D. Chuang, P. Leeds, H. Kim, 2009, Journal of neurochemistry.

Inhibition of Excessive Neuronal Apoptosis by the Calcium Antagonist Amlodipine and Antioxidants in Cerebellar Granule Cells

D. Chuang, P. Leeds, R. Jacob, 1999, Journal of neurochemistry.

Agonist-induced down-regulation and antagonist-induced up-regulation of m2- and m3-muscarinic acetylcholine receptor mRNA and protein in cultured cerebellar granule cells.

D. Chuang, F. Fukamauchi, C. Hough, 1993, Molecular pharmacology.

Transplantation of Mesenchymal Stem Cells Overexpressing FGF21 Facilitates Cognitive Recovery and Enhances Neurogenesis in a Mouse Model of Traumatic Brain Injury.

D. Chuang, Yun Wang, Y. Chiang, 2019, Journal of neurotrauma.

Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity

T. Chase, D. Chuang, Z. Qin, 2005, Neurobiology of Disease.

Neuroprotection against Apoptosis

D. Chuang, C. Hough, 2003 .

Neuroprotective effects of lithium in cultured cells and animal models of diseases.

D. Chuang, P. Leeds, E. Chalecka‐Franaszek, 2002, Bipolar disorders.

Long Term Lithium Treatment Suppresses p53 and Bax Expression but Increases Bcl-2 Expression

D. Chuang, Ren-wu Chen, 1999, The Journal of Biological Chemistry.

Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons

Z. Marinova, D. Chuang, P. Leeds, 2011, Neuropharmacology.

Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction

D. Chuang, P. Leeds, Y. Leng, 2004, Journal of neurochemistry.

GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE ,A POPTOSIS, AND NEURODEGENERATIVE DISEASES ∗

D. Chuang, V. Senatorov, C. Hough, 2005 .

Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases.

D. Chuang, V. Senatorov, De-Maw Chuang, 2005, Annual review of pharmacology and toxicology.

Nuclear localization of overexpressed glyceraldehyde-3-phosphate dehydrogenase in cultured cerebellar neurons undergoing apoptosis.

D. Chuang, M. Tanaka, K. Sunaga, 1998, Molecular pharmacology.

Subcellular Distribution of Glyceraldehyde‐3‐Phosphate Dehydrogenase in Cerebellar Granule Cells Undergoing Cytosine Arabinoside‐Induced Apoptosis

D. Chuang, E. Chalecka‐Franaszek, P. Saunders, 1997, Journal of neurochemistry.

Evidence that Glyceraldehyde‐3‐Phosphate Dehydrogenase Is Involved in Age‐Induced Apoptosis in Mature Cerebellar Neurons in Culture

D. Chuang, K. Sunaga, N. Katsube, 1996, Journal of neurochemistry.

The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons

Z. Marinova, D. Chuang, Min-Huei Liang, 2009, Molecular Psychiatry.

Ethanol induces subtype-specific up-regulation of muscarinic acetylcholine receptor mRNA in neurohybrid cell lines.

D. Chuang, F. Fukamauchi, Y. J. Wang, 1997, Life sciences.

Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome.

C. B. Smith, D. Chuang, Zhong-hua Liu, 2011, The international journal of neuropsychopharmacology.

Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling

J. Wendland, D. Chuang, Min-Huei Liang, 2008, Molecular and Cellular Neuroscience.

Turnover rate of tyrosine hydroxylase during Trans-synaptic induction.

D. Chuang, E. Costa, G. Zsilla, 1975, Molecular pharmacology.

Antidepressant mechanism of ketamine: perspective from preclinical studies

D. Chuang, Hsiao-Mei Liao, C. Chiu, 2015, Front. Neurosci..

Preclinical and Clinical Investigations of Mood Stabilizers for Huntington's Disease: What Have We Learned?

D. Chuang, Hsiao-Mei Liao, C. Chiu, 2014, International journal of biological sciences.

Roles of Glycogen Synthase Kinase-3 in Alzheimer's Disease: From Pathology to Treatment Target

D. Chuang, S. Leu, Hsing-Cheng Liu, 2012 .

Lithium Increases Transcription Factor Binding to AP‐1 and Cyclic AMP‐Responsive Element in Cultured Neurons and Rat Brain

D. Chuang, N. Ozaki, 1997, Journal of neurochemistry.

Nuclear Factor κB Nuclear Translocation Upregulates c-Myc and p53 Expression during NMDA Receptor-Mediated Apoptosis in Rat Striatum

T. Chase, D. Chuang, Z. Qin, 1999, The Journal of Neuroscience.

The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials.

D. Chuang, 2005, Annals of the New York Academy of Sciences.

Different signal transduction pathways are coupled to the nucleotide receptor and the P2Y receptor in C6 glioma cells.

D. Chuang, W. W. Lin, W. W. Lin, 1994, The Journal of pharmacology and experimental therapeutics.

Differences in the regulatory adaptation of the 5HT2 recognition sites labelled by 3H-mianserin or 3H-ketanserin

M. Barbaccia, D. Chuang, E. Costa, 1983, Neuropharmacology.

Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists.

D. Chuang, J. Xu, 1987, The Journal of pharmacology and experimental therapeutics.

Down-regulation of β-adrenergic receptors following repeated injections of desmethylimipramine: Permissive role of serotonergic axons

M. Barbaccia, D. Chuang, E. Costa, 1982, Neuropharmacology.

Homologous Desensitization of Muscarinic Cholinergic, Histaminergic, Adrenergic, and Serotonergic Receptors Coupled to Phospholipase C in Cerebellar Granule Cells

D. Chuang, Ora Dillon‐Carter, Ora Dillon‐Carter, 1989, Journal of neurochemistry.

Lithium neuroprotection: molecular mechanisms and clinical implications

D. Chuang, Michael K. Rowe, 2004, Expert Reviews in Molecular Medicine.

miR‐25 alleviates polyQ‐mediated cytotoxicity by silencing ATXN3

Li Zhang, D. Chuang, K. Xia, 2014, FEBS letters.

Expression and Agonist‐Induced Down‐Regulation of mRNAs of m2‐ and m3‐Muscarinic Acetylcholine Receptors in Cultured Cerebellar Granule Cells

D. Chuang, C. Hough, Fumihiko Fukamauchi, 1991, Journal of neurochemistry.

Functional MRI of Delayed Chronic Lithium Treatment in Rat Focal Cerebral Ischemia

Y. R. Kim, George Dai, B. Rosen, 2008, Stroke.

Lithium stimulates progenitor proliferation in cultured brain neurons

D. Chuang, P. Leeds, V. Senatorov, 2003, Neuroscience.

Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation

Takanobu Nakazawa, D. Chuang, Tadashi Yamamoto, 2002, Journal of neurochemistry.

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons.

D. Chuang, Y. Leng, P. Chen, 2008, The international journal of neuropsychopharmacology.

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx.

D. Chuang, C. Hough, S. Nonaka, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Lithium reduces BACE1 overexpression, β amyloid accumulation, and spatial learning deficits in mice with traumatic brain injury.

D. Chuang, F. Yu, Yumin Zhang, 2012, Journal of neurotrauma.

In Search of the Holy Grail for the Treatment of Neurodegenerative Disorders: Has a Simple Cation Been Overlooked?

H. Manji, D. Chuang, 2007, Biological Psychiatry.

The Antiapoptotic Actions of Mood Stabilizers

D. Chuang, 2005 .

beta-amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment.

D. Chuang, P. Leeds, W. Wei, 2000, European journal of pharmacology.

PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat

Robert B. Innis, Victor W. Pike, Sami S. Zoghbi, 2007, Neuroscience Letters.

Lithium protection from glutamate excitotoxicity: therapeutic implications

D. Chuang, 2004, Clinical Neuroscience Research.

Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity

D. Chuang, B. Lu, N. Takei, 2002, Neuropharmacology.

GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder

D. Chuang, Michael K. Rowe, C. Wiest, 2007, Neuroscience & Biobehavioral Reviews.

Effect of eukaryote DNA on amino acid incorporation in extracts of E. coli.

H. Weissbach, D. Chuang, 1973, Archives of biochemistry and biophysics.

Maitotoxin Induces Phosphoinositide Turnover and Modulates Glutamatergic and Muscarinic Cholinergic Receptor Function in Cultured Cerebellar Neurons

Wan-Wan Lin, D. Chuang, T. Yasumoto, 1990, Journal of neurochemistry.

Chronic haloperidol treatment attenuates receptor-mediated phosphoinositide turnover in rat brain slices

Rena Li, R. Wyatt, D. Chuang, 1991, Neuroscience Letters.

The mitochondrial hypothesis of bipolar disorder.

D. Chuang, C. Hough, 2000, Bipolar disorders.

An antisense oligodeoxynucleotide to glyceraldehyde-3-phosphate dehydrogenase blocks age-induced apoptosis of mature cerebrocortical neurons in culture.

D. Chuang, M. Kimura, M. Tanaka, 1996, The Journal of pharmacology and experimental therapeutics.

Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes

P. Gean, D. Chuang, Sufen Yang, 2006, Molecular Psychiatry.

Effect of cocaine, lidocaine kindling and carbamazepine on batrachotoxin-induced phosphoinositide hydrolysis in rat brain slices

R. Post, R. Margolis, D. Chuang, 1993, Brain Research.

Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases?

D. Chuang, 2004, Critical reviews in neurobiology.

Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition

D. Chuang, M. Ren, V. Senatorov, 2003, FEBS letters.

Serotonin‐Elicited Amplification of Adenylate Cyclase Activity in Hippocampal Membranes from Adult Rat

M. Barbaccia, D. Chuang, E. Costa, 1983, Journal of neurochemistry.

Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease

D. Chuang, P. Reddy, D. Tagle, 2003, Molecular and Cellular Neuroscience.

Chronic buspirone treatment differentially regulates 5-HT1A and 5-HT2A receptor mRNA and binding sites in various regions of the rat hippocampus.

D. Rubinow, D. Chuang, H. Chen, 1995, Brain research. Molecular brain research.

Polypeptide Hormones and Chromatin‐Associated Proteins Act as Acceptors for Cholera Toxin‐Catalyzed ADP‐Ribosylation

D. Chuang, J. Trepel, N. Neff, 1981, Journal of neurochemistry.

Inhibition of Excitatory Amino Acid‐Induced Phosphoinositide Hydrolysis as a Possible Mechanism of Nitroprusside Neurotoxicity

D. Chuang, O. Yu, 1996, Journal of neurochemistry.

Daily bupropion injections for 3 weeks attenuate the ne-stimulation of adenylate cyclase and the number of β-adrenergic recognition sites in rat frontal cortex

M. Barbaccia, D. Chuang, E. Costa, 1983, Neuropharmacology.

Bidirectional Synaptic Plasticity in the Rat Basolateral Amygdala: Characterization of an Activity-Dependent Switch Sensitive to the Presynaptic Metabotropic Glutamate Receptor Antagonist 2S-α-Ethylglutamic Acid

R. Post, M. Rogawski, D. Chuang, 1998, The Journal of Neuroscience.

Characterization of Two [3H]Ketanserin Recognition Sites in Rat Striatum

D. Chuang, S. Mclean, B. Roth, 1987, Journal of neurochemistry.

5-hydroxytryptamine2A receptor stimulation induces activator protein-1 and cyclic AMP-responsive element binding with cyclic AMP-responsive element-binding protein and jun D as common components in cerebellar neurons

D. Chuang, E. Chalecka‐Franaszek, H. Chen, 1999, Neuroscience.

Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats

D. Chuang, S. Nonaka, 1998, Neuroreport.

Valproic Acid and Other HDAC Inhibitors Upregulate FGF21 Gene Expression and Promote Process Elongation in Glia by Inhibiting HDAC2 and 3

D. Chuang, P. Leeds, Y. Leng, 2016, The international journal of neuropsychopharmacology.

m2- and m3-muscarinic acetylcholine receptor mRNAs have different responses to microtubule-affecting drugs

D. Chuang, F. Fukamauchi, C. Hough, 1991, Molecular and Cellular Neuroscience.

HDAC inhibitors mitigate ischemia-induced oligodendrocyte damage: potential roles of oligodendrogenesis, VEGF, and anti-inflammation.

D. Chuang, H. Kim, 2014, American journal of translational research.

Further studies on eukaryote DNA stimulation of amino acid incorporation in E. coli extracts.

H. Weissbach, D. Chuang, N. Chatterjee, 1974, Archives of biochemistry and biophysics.

A translocation-associated ribosomal conformational change detected by hydrogen exchange and sedimentation velocity.

D. Chuang, M. Simpson, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Paradoxical increase of 5-hydroxytryptamine2 receptors and 5-hydroxytryptamine2 receptor mRNA in cerebellar granule cells after persistent 5-hydroxytryptamine2 receptor stimulation.

D. Chuang, J. Akiyoshi, C. Hough, 1993, Molecular pharmacology.

The role of ribosomal conformation in protein synthesis: conformational changes in the ribosome during the tranlocation step.

D. Chuang, M. Simpson, H. A. Silberstein, 1971, Archives of biochemistry and biophysics.

Up-regulation of delta opioid receptors in neuroblastoma hybrid cells: evidence for differences in the mechanisms of action of sodium butyrate and naltrexone.

D. Chuang, J. Barg, X. M. Gao, 1991, The Journal of pharmacology and experimental therapeutics.

Phasic and tonic components in 5-HT2 receptor-mediated rat aorta contraction: participation of Ca++ channels and phospholipase C.

B. Roth, D. Chuang, E. Costa, 1985, The Journal of pharmacology and experimental therapeutics.

Characterization of Bradykinin‐Induced Phosphoinositide Turnover in Neurohybrid NCB‐20 Cells

D. Chuang, Ora Dillon‐Carter, Ora Dillon‐Carter, 1988, Journal of neurochemistry.

Regulation by batrachotoxin, veratridine, and monensin of basal and carbachol-induced phosphoinositide hydrolysis in neurohybrid NCB-20 cells

D. Chuang, 1990, Neurochemical Research.

Regulation of bradykinin-induced phosphoinositide turnover in cultured cerebellar astrocytes: possible role of protein kinase C

Wan-Wan Lin, D. Chuang, 1992, Neurochemistry International.

Carbachol-induced accumulation of inositol-1-phosphate in neurohybridoma NCB-20 cells: effects of lithium and phorbol esters.

D. Chuang, 1986, Biochemical and biophysical research communications.

5-Hydroxytryptamine2 receptors coupled to phospholipase C in rat aorta: modulation of phosphoinositide turnover by phorbol ester.

B. Roth, D. Chuang, E. Costa, 1986, The Journal of pharmacology and experimental therapeutics.

Increase in nerve growth factor content of C6 glioma cells by the activation of a β-adrenergic receptor

J. P. Schwartz, D. Chuang, E. Costa, 1977, Brain Research.

Glutamate-Modulating Drugs as a Potential Therapeutic Strategy in Obsessive-Compulsive Disorder

N. Fineberg, Z. Marinova, D. Chuang, 2017, Current neuropharmacology.

Serotonergic, adrenergic and histaminergic receptors coupled to phospholipase C in cultured cerebellar granule cells of rats.

D. Chuang, J. Xu, Jian Xu, 1987, Biochemical pharmacology.

Cross-desensitization of endothelin- and sarafotoxin-induced phosphoinositide turnover in neurons.

D. Chuang, C. Y. Lee, W. W. Lin, 1989, European journal of pharmacology.

Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder

Paul M. Jenkins, C. Ross, Shanshan Zhu, 2017, Proceedings of the National Academy of Sciences.

Endothelin- and sarafotoxin-induced phosphoinositide hydrolysis in cultured cerebellar granule cells: biochemical and pharmacological characterization.

D. Chuang, C. Y. Lee, W. W. Lin, 1991, The Journal of pharmacology and experimental therapeutics.

Effects of Depolarization and NMDA Antagonists on the Survival of Cerebellar Granule Cells: A Pivotal Role for Protein Kinase C Isoforms

Wan-Wan Lin, D. Chuang, Ching-Wen Wang, 1997, Journal of neurochemistry.

Molecular mechanisms in the action of imipramine

M. Barbaccia, D. Chuang, E. Costa, 1983, Experientia.

Lithium‐induced inhibition of Src tyrosine kinase in rat cerebral cortical neurons: a role in neuroprotection against N‐methyl‐D‐aspartate receptor‐mediated excitotoxicity

D. Chuang, K. Fujimaki, R. Hashimoto, 2003, FEBS letters.

Protein phosphorylation in nuclei of adrenal medulla incubated with cyclic adenosine 3':5'-monophosphate-dependent protein kinase.

D. Chuang, E. Costa, R. Hollenbeck, 1977, The Journal of biological chemistry.

Safety and efficacy of valproic acid treatment in SCA3/MJD patients.

D. Chuang, B. Tang, Hong Jiang, 2016, Parkinsonism & related disorders.

Novel integrative genomic tool for interrogating lithium response in bipolar disorder

M. Alda, A. Elkahloun, D. Chuang, 2015, Translational Psychiatry.

Lentivirally mediated GSK-3β silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice.

D. Chuang, P. Leeds, Y. Leng, 2011, The international journal of neuropsychopharmacology.

Role of second messengers in agonist up-regulation of 5-HT2A (5-HT2) receptor binding sites in cerebellar granule neurons: involvement of calcium influx and a calmodulin-dependent pathway.

D. Chuang, H. Chen, H. Li, 1995, The Journal of pharmacology and experimental therapeutics.

ONO-1603, a potential antidementia drug, shows neuroprotective effects and increases m3-muscarinic receptor mRNA levels in differentiating rat cerebellar granule neurons

D. Chuang, K. Sunaga, N. Katsube, 1996, Neuroscience Letters.

Control of Nuclear Function in Chromaffin Cells by Persistent Activation of Nicotinic Receptors

A. Guidotti, D. Chuang, E. Costa, 1978 .

Neurotrophin Protection Against Toxicity Induced by Low Potassium and Nitroprusside in Cultured Cerebellar Granule Neurons

D. Chuang, O. Yu, 1997, Journal of neurochemistry.

Enhanced template activity in chromatin from adrenal medulla after phosphorylation of chromosomal proteins.

D. Chuang, E. Costa, R. Hollenbeck, 1976, Science.

Translocation of cytosol protein kinase into nuclei and the induction of tyrosine hydroxylase in NBD-2 neuroblastoma cells

D. Chuang, E. Costa, R. Hollenbeck, 1979, Brain Research.

Molecular biology of tyrosine hydroxylase induction

A. Guidotti, E. Costa, K. Kumakura, 1981 .

Trans-synaptic regulation of ribonucleic acid biosynthesis in rat adrenal medulla.

D. Chuang, E. Costa, 1976, Molecular pharmacology.

Tryptamine Induces Phosphoinositide Turnover and Modulates Adrenergic and Muscarinic Cholinergic Receptor Function in Cultured Cerebellar Granule Cells

D. Chuang, M. Kimura, R. Ishitani, 1994, Journal of neurochemistry.

Assessment of lithium treatment using fMRI during stroke recovery in rats

Y. R. Kim, J. Mandeville, B. Rosen, 2005 .

Antagonist-induced transient down-regulation of delta-opioid receptors in NG108-15 cells.

D. Chuang, J. Barg, X. M. Gao, 1992, Molecular pharmacology.

Endothelin-induced activation of phosphoinositide turnover, calcium mobilization, and transmitter release in cultured neurons and neurally related cell types.

D. Chuang, C. Y. Lee, W. W. Lin, 1991, Journal of cardiovascular pharmacology.

Preventing the Sequelae of Concussions and Traumatic Brain Injury

D. Chuang, 2014 .

Carbamazepine-induced neurotoxicity and its prevention by NMDA in cultured cerebellar granule cells

D. Chuang, Xiao-Ming Gao, 1992, Neuroscience Letters.

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

S. Haggarty, S. Carr, R. Sidman, 2017, Proceedings of the National Academy of Sciences.

Potential mechanisms underlying lithium treatment for Alzheimer's disease and COVID-19.

D. Chuang, G. Liang, H. Wei, 2022, European review for medical and pharmacological sciences.

GABA pretreatment enhances glutamate mediated phosphoinositide hydrolysis in neurons.

D. Chuang, O. Yu, 1988, European journal of pharmacology.

Characterization of 5-HT2 receptors linked to phospholipase C in rat aorta

B. Roth, D. Chuang, T. Nakaki, 1985 .