B. Pike

发表

Diffusion Magnetic Resonance Imaging Study of a Rat Hippocampal Slice Model for Acute Brain Injury

S. Blackband, T. Shepherd, P. Thelwall, 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Effects of injury severity on regional and temporal mRNA expression levels of calpains and caspases after traumatic brain injury in rats.

B. Pike, R. Hayes, P. Tolentino, 2004, Journal of neurotrauma.

Concurrent Assessment of Calpain and Caspase-3 Activation after Oxygen–Glucose Deprivation in Primary Septo-Hippocampal Cultures

B. Pike, R. Hayes, Kevin K. W. Wang, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Stretch injury causes calpain and caspase-3 activation and necrotic and apoptotic cell death in septo-hippocampal cell cultures.

B. Pike, R. Hayes, D. Anderson, 2000, Journal of neurotrauma.

Systemic administration of a calpain inhibitor reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat.

F. Angileri, A. Day, P. Bramanti, 2002, Journal of neurotrauma.

TNF‐α stimulates caspase‐3 activation and apoptotic cell death in primary septo‐hippocampal cultures

Douglas K. Anderson, B. Pike, R. Hayes, 2001, Journal of neuroscience research.

Characterization of the bovine neurofilament NF-M protein and cDNA sequence, and identification of in vitro and in vivo calpain cleavage sites.

B. Pike, G. Shaw, Lu Zhang, 2004, Biochemical and biophysical research communications.

Up‐regulation of tissue‐type transglutaminase after traumatic  brain injury

B. Pike, R. Hayes, Kevin K. W. Wang, 2002, Journal of neurochemistry.

Regional calpain and caspase‐3 proteolysis of α‐spectrin after traumatic brain injury

B. Pike, R. Hayes, Kevin K. W. Wang, 1998, Neuroreport.

Activation of phosphatidylinositol 3‐kinase by brain‐derived neurotrophic factor gene transfection in septo‐hippocampal cultures

G. Clifton, B. Pike, R. Hayes, 1998, Journal of neuroscience research.

Novel Characteristics of Glutamate-Induced Cell Death in Primary Septohippocampal Cultures: Relationship to Calpain and Caspase-3 Protease Activation

B. Pike, R. Hayes, Kevin K. W. Wang, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Subcellular Localization and Duration of μ-Calpain and m-Calpain Activity after Traumatic Brain Injury in the Rat: A Casein Zymography Study

G. Clifton, B. Pike, R. Hayes, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Altered calpastatin protein levels following traumatic brain injury in rat.

B. Pike, R. Hayes, X. Zhao, 1999, Journal of neurotrauma.

Temporal Profile of Apoptotic-like Changes in Neurons and Astrocytes Following Controlled Cortical Impact Injury in the Rat

B. Pike, R. Hayes, X. Zhao, 1999, Experimental Neurology.

Award Number : DAMD 17-011-0765 TITLE : Common Mechanisms of Neuronal Cell Death After Exposure to Diverse Environmental Insults : Implications for Treatment PRINCIPAL INVESTIGATOR :

B. Pike, G. Shaw, D. Ph., 2022 .

Temporal and spatial profile of caspase 8 expression and proteolysis after experimental traumatic brain injury

John Calvin Reed, S. Krajewski, B. Pike, 2001, Journal of neurochemistry.

Accumulation of non‐erythroid αII‐spectrin and calpain‐cleaved αII‐spectrin breakdown products in cerebrospinal fluid after traumatic brain injury in rats

Jeremy J. Flint, Ronald L. Hayes, B. Pike, 2001 .

The Effect of Postinjury Kindled Seizures on Cognitive Performance of Traumatically Brain-Injured Rats

B. Pike, R. Hamm, B. Lyeth, 1995, Experimental Neurology.

The rotarod test: an evaluation of its effectiveness in assessing motor deficits following traumatic brain injury.

B. Pike, L. Jenkins, R. Hamm, 1994, Journal of neurotrauma.

Maitotoxin Induces Calpain But Not Caspase-3 Activation and Necrotic Cell Death in Primary Septo-Hippocampal Cultures

R. L. Hayes, B. Pike, R. Hayes, 1999, Neurochemical Research.

Temporal relationships between de novo protein synthesis, calpain and caspase 3‐like protease activation, and DNA fragmentation during apoptosis in septo‐hippocampal cultures

B. Pike, R. Hayes, Kevin K. W. Wang, 1998, Journal of neuroscience research.

Cell-specific upregulation of survivin after experimental traumatic brain injury in rats.

B. Pike, R. Hayes, Kevin K. W. Wang, 2004, Journal of neurotrauma.

Temporal and Spatial Profile of Bid Cleavage after Experimental Traumatic Brain Injury

John Calvin Reed, S. Krajewski, B. Pike, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Temporal Profile and Cell Subtype Distribution of Activated Caspase‐3 Following Experimental Traumatic Brain Injury

B. Pike, R. Hayes, W. Poewe, 2000, Journal of neurochemistry.

Accumulation of Calpain and Caspase-3 Proteolytic Fragments of Brain-Derived αII-Spectrin in Cerebral Spinal Fluid after Middle Cerebral Artery Occlusion in Rats

F. Tortella, B. Pike, R. Hayes, 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Post-injury administration of BIBN 99, a selective muscarinic M2 receptor antagonist, improves cognitive performance following traumatic brain injury in rats

B. Pike, R. Hamm, 1995, Brain Research.

pH dependency of μ-calpain and m-calpain activity assayed by casein zymography following traumatic brain injury in the rat

B. Pike, R. Hayes, X. Zhao, 1998, Neuroscience Letters.

Accumulation of non-erythroid alpha II-spectrin and calpain-cleaved alpha II-spectrin breakdown products in cerebrospinal fluid after traumatic brain injury in rats.

B. Pike, R. Hayes, K. Wang, 2001, Journal of neurochemistry.

Protective effects of moderate hypothermia on behavioral deficits but not necrotic cavitation following cortical impact injury in the rat.

F. Angileri, G. Clifton, B. Pike, 1998, Journal of neurotrauma.

Increased expression and processing of caspase‐12 after traumatic brain injury in rats

B. Pike, R. Hayes, Kevin K. W. Wang, 2003, Journal of neurochemistry.

Hyperphosphorylated neurofilament NF-H is a serum biomarker of axonal injury.

Gerry Shaw, Douglas K. Anderson, S. Scheff, 2005, Biochemical and biophysical research communications.