J. Simorre

发表

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit

N. Daigle, J. Ellenberg, C. Bougault, 2007, Nature Structural &Molecular Biology.

Interlocking structural motifs mediate molecular discrimination by a theophylline-binding RNA

Grant R. Zimmermann, A. Pardi, G. Zimmermann, 1997, Nature Structural Biology.

Kissing-Loop Interaction in the 3′ End of the Hepatitis C Virus Genome Essential for RNA Replication

Ralf Bartenschlager, Peter Friebe, R. Bartenschlager, 2005, Journal of Virology.

Outer-membrane lipoprotein LpoB spans the periplasm to stimulate the peptidoglycan synthase PBP1B

C. Bougault, A. Typas, J. Simorre, 2014, Proceedings of the National Academy of Sciences.

LpoA : Implications for PBP 1 A Stimulation

C. Bougault, I. Ayala, J. Simorre, 2014 .

Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.

P. Gans, J. Simorre, R. Cross, 2003, Biochemistry.

Hybrid Potential Simulation of the Acylation of Enterococcus faecium l,d-Transpeptidase by Carbapenems.

M. Field, C. Bougault, J. Simorre, 2016, The journal of physical chemistry. B.

Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase

E. Brown, J. Simorre, N. Strynadka, 2020, The Journal of Biological Chemistry.

Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus

C. Bougault, I. Ayala, J. Simorre, 2019, Front. Microbiol..

Method for evaluating the reliability of distances and rotational correlation times deduced from 2D 1H NMR NOESY experiments

J. Simorre, D. Genest, 1990 .

Defining the function of OmpA in the Rcs stress response

J. Simorre, J. Collet, B. Iorga, 2020, bioRxiv.

1H, 13C and 15N resonance assignments of YajG, an Escherichiacoli protein of unknown structure and function

C. Bougault, B. Joris, J. Boudet, 2007, Biomolecular NMR Assignments.

The interactions of substituted pyrido[1,2-e]purines with oligonucleotides depend on the amphiphilic properties of their side chain.

J. Simorre, A. Gueiffier, V. Dabouis, 1999, Archives of biochemistry and biophysics.

Suppression of artifacts induced by homonuclear decoupling in amino-acid-type edited methyl 1H-13C correlation experiments.

J. Simorre, B. Brutscher, H. Van Melckebeke, 2004, Journal of magnetic resonance.

Base-type-selective high-resolution 13C edited NOESY for sequential assignment of large RNAs

J. Boisbouvier, E. Kupče, J. Simorre, 2001, Journal of biomolecular NMR.

Central Domain of DivIB Caps the C-terminal Regions of the FtsL/DivIC Coiled-coil Rod*

T. Vernet, J. Simorre, F. Gabel, 2009, The Journal of Biological Chemistry.

Isolation and analysis of cell wall components from Streptococcus pneumoniae.

A. Tomasz, C. Bougault, J. Simorre, 2012, Analytical biochemistry.

Solid-state NMR on bacterial cells: selective cell wall signal enhancement and resolution improvement using dynamic nuclear polarization.

I. Ayala, J. Simorre, M. Bardet, 2013, Journal of the American Chemical Society.

Structure of the heterotrimeric complex that regulates type III secretion needle formation

J. Simorre, C. Contreras-Martel, A. Dessen, 2007, Proceedings of the National Academy of Sciences.

DltC acts as an interaction hub for AcpS, DltA and DltB in the teichoic acid d-alanylation pathway of Lactiplantibacillus plantarum

I. Ayala, J. Simorre, C. Grangeasse, 2022, Scientific reports.

Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme.

O. Uhlenbeck, A. Pardi, J. Simorre, 1998, Biochemistry.

Combined structural and biochemical analysis of the H-T complex in the glycine decarboxylase cycle: evidence for a destabilization mechanism of the H-protein.

P. Gans, M. Blackledge, J. Simorre, 2000, Biochemistry.

Solid State NMR Studies of Intact Lipopolysaccharide Endotoxin.

P. Schanda, J. Simorre, A. Molinaro, 2018, ACS chemical biology.

1H and 13C NMR assignment and secondary structure of Chlorobium limicola f. thiosulfatophilum ferrocytochrome c 555

J. Simorre, D. Marion, M. Caffrey, 1995, FEBS letters.

Solution structure of 2-(pyrido[1,2-e]purin-4-yl)amino-ethanol intercalated in the DNA duplex d(CGATCG)2.

M. Blackledge, J. Simorre, D. Marion, 2001, Biochemistry.

A Peptidoglycan Fragment Triggers β-lactam Resistance in Bacillus licheniformis

A. Luxen, B. Joris, J. Boudet, 2012, PLoS pathogens.

Three-dimensional structure in solution of a wheat lipid-transfer protein from multidimensional 1H-NMR data. A new folding for lipid carriers.

M Ptak, D. Marion, J. Simorre, 1994, European journal of biochemistry.

, François Pseudomonas aeruginosa the Type III Secretion System of the Major Translocator Protein PopB of Membrane and Chaperone Recognition by Protein Structure and Folding :

J. Simorre, A. Förster, A. Dessen, 2014 .

Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosa*

J. Simorre, A. Förster, A. Dessen, 2013, The Journal of Biological Chemistry.

Resolution-Enhanced Base-Type-Edited HCN Experiment for RNA

A. Pardi, J. Boisbouvier, J. Simorre, 2005, Journal of biomolecular NMR.

Studying intact bacterial peptidoglycan by proton-detected NMR spectroscopy at 100 kHz MAS frequency.

C. Bougault, I. Ayala, P. Schanda, 2019, Journal of structural biology.

Amino acid-type edited NMR experiments for methyl-methyl distance measurement in 13C-labeled proteins.

J. Simorre, B. Brutscher, H. Van Melckebeke, 2004, Journal of the American Chemical Society.

Structure–function analysis of the extracellular domain of the pneumococcal cell division site positioning protein MapZ

C. Bougault, J. Simorre, C. Grangeasse, 2016, Nature Communications.

Longitudinal-relaxation-enhanced NMR experiments for the study of nucleic acids in solution.

A. Pardi, J. Boisbouvier, P. Schanda, 2009, Journal of the American Chemical Society.

Transverse relaxation optimized HCN experiment for nucleic acids: Combining the advantages of TROSY and MQ spin evolution

J. Simorre, B. Brutscher, 2001, Journal of biomolecular NMR.

Improved Sensitivity and Resolution in 1 H- 13 C NMR Experiments of RNA

A. Pardi, J. Boisbouvier, J. Simorre, 1998 .

Design of a Complete Set of Two-Dimensional Triple-Resonance Experiments for Assigning Labeled Proteins

J. Simorre, D. Marion, B. Brutscher, 1994 .

Assignment of NMR spectra of proteins using triple-resonance two-dimensional experiments

B Brutscher, J. Simorre, D. Marion, 1994, Journal of biomolecular NMR.

The lipopolysaccharide-transporter complex LptB2FG also displays adenylate kinase activity in vitro dependent on the binding partners LptC/LptA

I. Ayala, J. Simorre, E. C. M. Moura, 2021, The Journal of biological chemistry.

LptB2FG is an ABC transporter with Adenylate Kinase activity regulated by LptC/A recruitment

I. Ayala, J. Simorre, E. C. M. Moura, 2021, bioRxiv.

Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division

C. Gross, K. C. Huang, J. Simorre, 2015, eLife.

Conformational and thermodynamic changes of the repressor/DNA operator complex upon monomerization shed new light on regulation mechanisms of bacterial resistance against β-lactam antibiotics

M. Blackledge, B. Joris, J. Boudet, 2007, Nucleic acids research.

Triple resonance HNCCCH experiments for correlating exchangeable and nonexchangeable cytidine and uridine base protons in RNA

L. Mueller, B. Farmer, A. Pardi, 1995, Journal of biomolecular NMR.

TRIPLE-RESONANCE EXPERIMENTS FOR ASSIGNMENT OF ADENINE BASE RESONANCES IN 13C/15N-LABELED RNA

L. Mueller, A. Pardi, G. Zimmermann, 1996 .

Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni

M. Murphy, J. Simorre, L. McIntosh, 2021, The Journal of biological chemistry.

C5-epimerase and 2-O-sulfotransferase associate in vitro to generate contiguous epimerized and 2-O-sulfated heparan sulfate domains.

J. Simorre, H. Lortat-Jacob, C. Laguri, 2015, ACS chemical biology.

NMR characterization of the interaction between the C-terminal domain of interferon-gamma and heparin-derived oligosaccharides.

Hugues Lortat-Jacob, P. Gans, J. Simorre, 2004, The Biochemical journal.

Induced conformational changes activate the peptidoglycan synthase PBP1B

C. Bougault, I. Ayala, J. Simorre, 2018, Molecular microbiology.

NMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C Virus*

C. Chipot, F. Penin, J. Dubuisson, 2010, The Journal of Biological Chemistry.

Dynamics characterization of fully hydrated bacterial cell walls by solid-state NMR: evidence for cooperative binding of metal ions.

C. Bougault, B. Joris, J. Simorre, 2010, Journal of the American Chemical Society.

Thanatin Impairs Lipopolysaccharide Transport Complex Assembly by Targeting LptC–LptA Interaction and Decreasing LptA Stability

J. Simorre, A. Romanelli, E. C. M. Moura, 2020, Frontiers in Microbiology.

Interaction of lipopolysaccharides at intermolecular sites of the periplasmic Lpt transport assembly

C. Bougault, I. Ayala, J. Simorre, 2017, Scientific Reports.

SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli

J. Simorre, E. Breukink, N. Strynadka, 2020, mBio.

Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK.

S. Cusack, J. Simorre, G. Núñez, 2007, Journal of molecular biology.

A conformational change in the catalytic core of the hammerhead ribozyme upon cleavage of an RNA substrate.

A. Pardi, J. Simorre, P. Legault, 1997, Biochemistry.

The noncatalytic triad of α‐amylases: A novel structural motif involved in conformational stability

J. Simorre, G. Feller, P. Ramteke, 2008, Proteins.

Dynamics induced by β-lactam antibiotics in the active site of Bacillus subtilis L,D-transpeptidase.

C. Bougault, J. Simorre, O. Pessey, 2012, Structure.

Guanidinium chloride denaturation of the dimeric Bacillus licheniformis BlaI repressor highlights an independent domain unfolding pathway.

J. Frère, B. Joris, J. Simorre, 2004, The Biochemical journal.

Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain.

Andrew A McCarthy, Winfried Weissenhorn, W. Weissenhorn, 2010, Cell host & microbe.

DltC acts as an interaction hub for AcpS, DltA and DltB in the teichoic acid d-alanylation pathway of Lactiplantibacillus plantarum

I. Ayala, J. Simorre, C. Grangeasse, 2022, Scientific Reports.

Sequential 1H and 15N NMR resonance assignment and secondary structure of ferrocytochrome c2 from Rhodobacter sphaeroides.

P. Gans, J. Simorre, D. Marion, 1996, Journal of biochemistry.

Assignment of the 13C and 13CO resonances for Rhodobacter capsulatus ferrocytochrome c2 using double-resonance and triple-resonance NMR spectroscopy.

J. Simorre, D. Marion, B. Brutscher, 1994, European journal of biochemistry.

Windowed R-PDLF recoupling: a flexible and reliable tool to characterize molecular dynamics.

J. Simorre, S. Hediger, A. Gansmüller, 2013, Journal of magnetic resonance.

Identification and characterization of a novel high affinity metal-binding site in the hammerhead ribozyme.

A. Pardi, J. Simorre, L. Beigelman, 1999, RNA.

Profiling sulfation/epimerization pattern of full-length heparan sulfate by NMR following cell culture 13C-glucose metabolic labeling.

P. Gans, J. Simorre, H. Lortat-Jacob, 2015, Glycobiology.

Two- and three-dimensional 1H NMR studies of a wheat phospholipid transfer protein: sequential resonance assignments and secondary structure.

J. Simorre, D. Marion, M. Ptak, 1991, Biochemistry.

Suppressor Mutations in LptF Bypass Essentiality of LptC by Forming a Six-Protein Transenvelope Bridge That Efficiently Transports Lipopolysaccharide

J. Simorre, D. Kahne, E. C. M. Moura, 2022, mBio.

Antibacterial potency of type VI amidase effector toxins is dependent on substrate topology and cellular context

L. Starita, J. Simorre, P. Brzovic, 2022, bioRxiv.

Substrate topology and cognate immunity modulate antibacterial toxicity of Tae cell wall hydrolases

L. Starita, J. Simorre, P. Brzovic, 2022 .

Progress in multidimensional NMR investigations of peptide and protein 3-D structures in solution. From structure to functional aspects.

J. Simorre, X. Gallet, J. Bonmatin, 1992, Biochimie.

13C-labeled heparan sulfate analogue as a tool to study protein/heparan sulfate interactions by NMR spectroscopy: application to the CXCL12α chemokine.

P. Gans, A. Imberty, J. Simorre, 2011, Journal of the American Chemical Society.

Structural features of the interaction of MapZ with FtsZ and membranes in Streptococcus pneumoniae

C. Bougault, I. Ayala, B. Habenstein, 2020, Scientific Reports.

Coupling of polymerase and carrier lipid phosphatase prevents product inhibition in peptidoglycan synthesis

J. Simorre, E. Breukink, M. VanNieuwenhze, 2018, Cell surface.

NMR Determination of Sugar Puckers in Nucleic Acids from CSA−Dipolar Cross-Correlated Relaxation

A. Pardi, J. Boisbouvier, J. Simorre, 2000 .

The unique three-dimensional arrangement of Macrophage Galactose Lectin enables E. coli LipoPolySaccharides recognition through two distinct interfaces

I. Ayala, J. Simorre, J. Kleman, 2023, bioRxiv.

Negative Impact of Carbapenem Methylation on the Reactivity of β-Lactams for Cysteine Acylation as Revealed by Quantum Calculations and Kinetic Analyses

M. Field, C. Bougault, J. Simorre, 2019, Antimicrobial Agents and Chemotherapy.

Kinetic Features of L,D-Transpeptidase Inactivation Critical for β-Lactam Antibacterial Activity

C. Bougault, L. Rice, J. Simorre, 2013, PloS one.

Structure of Enterococcus faeciuml,d-transpeptidase acylated by ertapenem provides insight into the inactivation mechanism.

C. Bougault, J. Simorre, M. Arthur, 2013, ACS chemical biology.

Elongated Structure of the Outer-Membrane Activator of Peptidoglycan Synthesis LpoA: Implications for PBP1A Stimulation

Waldemar Vollmer, C. Bougault, I. Ayala, 2014, Structure.

A gp41 MPER-specific Llama VHH Requires a Hydrophobic CDR3 for Neutralization but not for Antigen Recognition

W. Weissenhorn, R. Weiss, J. Simorre, 2013, PLoS pathogens.

Solution structural study of BlaI: implications for the repression of genes involved in beta-lactam antibiotic resistance.

P. Gans, B. Joris, J. Simorre, 2003, Journal of molecular biology.

Compensated second-order recoupling: application to third spin assisted recoupling.

R. Griffin, J. Simorre, M. Bardet, 2012, Physical chemistry chemical physics : PCCP.

Refinement of local and long-range structural order in theophylline-binding RNA using (13)C-(1)H residual dipolar couplings and restrained molecular dynamics.

A. Pardi, M. Blackledge, J. Simorre, 2001, Journal of the American Chemical Society.

Atomic model of a cell-wall cross-linking enzyme in complex with an intact bacterial peptidoglycan.

C. Bougault, I. Ayala, P. Schanda, 2014, Journal of the American Chemical Society.

NMR assignment of Rhodobacter capsulatus ferricytochrome c', a 28 kDa paramagnetic heme protein.

B Brutscher, J. Simorre, D. Marion, 1995, Biochemistry.

1H, 13C, 15N-NMR resonance assignments of oxidized thioredoxin h from the eukaryotic green alga Chlamydomonas reinhardtii using new methods based on two-dimensional triple-resonance NMR spectroscopy and computer-assisted backbone assignment.

J. Simorre, D. Marion, B. Brutscher, 1995, European journal of biochemistry.

Cell division of Streptococcus pneumoniae: think positive!

J. Simorre, C. Brochier-Armanet, C. Grangeasse, 2016, Current opinion in microbiology.

Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.

E. Brown, J. Simorre, N. Strynadka, 2020 .

Characterization of the dynamic properties of Rhodobacter capsulatus ferricytochrome c′ — a 28 kDa paramagnetic heme protein

J. Simorre, D. Marion, M. Caffrey, 1995, FEBS letters.

Macromolecular import into Escherichia coli: the TolA C-terminal domain changes conformation when interacting with the colicin A toxin.

J. Simorre, M. Gavioli, D. Marion, 2002, Biochemistry.

Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa

I. Ayala, J. Simorre, E. Breukink, 2020, Structure.

Chemical shift perturbations induced by the acylation of Enterococcus faeciuml,d-transpeptidase catalytic cysteine with ertapenem

C. Bougault, J. Simorre, M. Arthur, 2014, Biomolecular NMR Assignments.

Acyl acceptor recognition by Enterococcus faecium l,d‐transpeptidase Ldtfm

C. Bougault, J. Simorre, M. Arthur, 2015, Molecular microbiology.

Toward the characterization of peptidoglycan structure and protein-peptidoglycan interactions by solid-state NMR spectroscopy.

C. Bougault, B. Joris, J. Simorre, 2008, Journal of the American Chemical Society.

Optimization of multidimensional NMR using band-selective pulses

J. Simorre, D. Marion, B. Brutscher, 1992 .

Dynamics induced by β-lactam antibiotics in the active site of Bacillus subtilis L,D-transpeptidase.

C. Bougault, J. Simorre, M. Arthur, 2012, Structure.

High-resolution 3D HNCOCA experiment applied to a 28 kDa paramagnetic protein

J. Simorre, D. Marion, B. Brutscher, 1995, Journal of biomolecular NMR.

Computer assignment of the backbone resonances of labelled proteins using two-dimensional correlation experiments

J. Simorre, B. Brutscher, Dominique Marion, 1995, Journal of biomolecular NMR.

13C spin relaxation measurements in RNA: Sensitivity and resolution improvement using spin-state selective correlation experiments

J. Boisbouvier, J. Simorre, D. Marion, 1999 .

Solution NMR assignment of LpoB, an outer-membrane anchored Penicillin-Binding Protein activator from Escherichia coli

C. Bougault, J. Simorre, W. Vollmer, 2014, Biomolecular NMR assignments.

Backbone and side-chain 1H, 15N and 13C assignment of apo- and imipenem-acylated l,d-transpeptidase from Bacillus subtilis

C. Bougault, J. Simorre, J. Hugonnet, 2012, Biomolecular NMR Assignments.

Solid-state NMR on bacterial cells: selective cell wall signal enhancement and resolution improvement using dynamic nuclear polarization.

I. Ayala, J. Simorre, M. Bardet, 2013, Journal of the American Chemical Society.

Deciphering the structural attributes of protein-heparan sulfate interactions using chemo-enzymatic approaches and NMR spectroscopy.

J. Simorre, C. Laguri, Aurélie Préchoux, 2021, Glycobiology.

Monitoring Drug-Protein Interactions in the Bacterial Periplasm by Solution Nuclear Magnetic Resonance Spectroscopy.

C. Bougault, J. Simorre, A. Dessen, 2024, Journal of the American Chemical Society.

Chemical shift perturbations induced by the acylation of Enterococcus faeciuml,d-transpeptidase catalytic cysteine with ertapenem

C. Bougault, J. Simorre, M. Arthur, 2013, Biomolecular NMR Assignments.

Acquisition schemes and quadrature artifacts in phase-sensitive two-dimensional NMR

J. Simorre, D. Marion, 1990 .