H. Tai

发表

Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2.

Hoon Cho, Lingyu Huang, A. Hamza, 2006, Bioorganic & medicinal chemistry.

Free-energy perturbation simulation on transition states and redesign of butyrylcholinesterase.

Fang Zheng, Chang-Guo Zhan, C. Zhan, 2009, Biophysical journal.

15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers.

J. Lutterbaugh, R. Rerko, J. Willis, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Activation of Thromboxane A2 Receptor (TP) Increases the Expression of Monocyte Chemoattractant Protein -1 (MCP-1)/Chemokine (C-C motif) Ligand 2 (CCL2) and Recruits Macrophages to Promote Invasion of Lung Cancer Cells

H. Tai, Xiuling Li, 2013, PloS one.

Novel human mPGES-1 inhibitors identified through structure-based virtual screening.

Chang-Guo Zhan, Adel Hamza, A. Hamza, 2011, Bioorganic & medicinal chemistry.

Immunoassay detection of drugs in racing horses: detection of ethacrynic acid and bumetanide in equine urine by ELISA.

H. Tai, D. Watt, S. Stanley, 1994, Journal of analytical toxicology.

15-Hydroxyprostaglandin Dehydrogenase Protein Expression in Human Fetal Membranes With and Without Subclinical Inflammation

H. Tai, A. Bocking, S. Keating, 2007, Reproductive Sciences.

Structural and functional characterization of human microsomal prostaglandin E synthase-1 by computational modeling and site-directed mutagenesis.

Chang-Guo Zhan, D. Gao, C. Zhan, 2006, Bioorganic & medicinal chemistry.

15-hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer.

B. Karlan, H. Tai, H. Koeffler, 2006, Cancer research.

Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells.

H. Tai, M. Tong, 2004, Endocrinology.

The role of N-glycosylation of human thromboxane A2 receptor in ligand binding.

H. Tai, N. Chiang, 1998, Archives of biochemistry and biophysics.

Prostaglandin E2 receptor EP3alpha subtype: the role of N-glycosylation in ligand binding as revealed by site-directed mutagenesis.

H. Tai, C. Huang, 1998, Prostaglandins, leukotrienes, and essential fatty acids.

15‐hydroxyprostaglandin dehydrogenase suppresses K‐RasV12‐dependent tumor formation in Nu/Nu mice

H. Tai, G. Eibl, L. Slice, 2008, Molecular carcinogenesis.

Arachidonic Acid and Its Metabolites in Cerebral Ischemia a

H. Tai, J. Chao, E. Hogan, 1989, Annals of the New York Academy of Sciences.

Thiamine transporter gene expression and exogenous thiamine modulate the expression of genes involved in drug and prostaglandin metabolism in breast cancer cells.

A. Stromberg, H. Tai, Shuqiang Liu, 2004, Molecular cancer research : MCR.

C-Terminal region of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates.

H. Tai, H. Zhou, F. Yan, 2001, European journal of biochemistry.

Squalene epoxidase of rat liver.

H. Tai, K. Bloch, H H Tai, 1972, The Journal of biological chemistry.

Preparation of 125I-labeled secretin of high specific radioactivity.

H. Tai, W. Chey, B. Korsch, 1975, Analytical biochemistry.

Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation.

A. Hamza, C. Zhan, H. Tai, 2005, Bioorganic & medicinal chemistry.

Structure and function of human NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase.

H. Tai, Huiping Zhou, F. Yan, 2002, Advances in experimental medicine and biology.

Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesis.

A. Hamza, C. Zhan, H. Tai, 2010, The journal of physical chemistry. B.

Histone deacetylase inhibitors and transforming growth factor-β induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells

H. Tai, M. Tong, Yunfei Ding, 2006 .

15-Hydroxyprostaglandin Dehydrogenase Is Down-regulated in Colorectal Cancer*

H. Tai, V. Holla, M. Backlund, 2005, Journal of Biological Chemistry.

15-hydroxyprostaglandin dehydrogenase (15-PGDH) and lung cancer.

H. Tai, M. Tong, Yunfei Ding, 2007, Prostaglandins & other lipid mediators.

NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer.

H. Tai, Shuqiang Liu, M. Tong, 2004, Carcinogenesis.

Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

K. Bae, J. Sanabria, L. Kasturi, 2015, Science.

(15-PGDH) BEHAVES AS A TUMOR SUPPRESSOR IN LUNG CANCER 1

H. Tai, Shuqiang Liu, M. Tong, 2004 .

Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine.

Zhenyu Jin, C. Zhan, H. Tai, 2013, The Biochemical journal.

15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells.

H. Tai, M. Tong, X. Chi, 2009, Archives of biochemistry and biophysics.

Polycyclic aromatic hydrocarbons affect the calcium ionophore induced activation of rabbit platelet

H. Tai, A. Yamauchi, Hiroyasu Yamazaki, 1990 .

Serine 331 is major site of phosphorylation and desensitization induced by protein kinase C in thromboxane receptor alpha.

H. Tai, Huiping Zhou, D. Liao, 2002, Acta pharmacologica Sinica.

15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors

M. Bertagnolli, J. Lutterbaugh, R. Rerko, 2009, Proceedings of the National Academy of Sciences.

Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes.

H. Tai, K. Subbaramaiah, A. Dannenberg, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Dexamethasone inhibits the induction of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase by phorbol ester in human promonocytic U937 cells.

H. Tai, M. Tong, 2000, Biochimica et biophysica acta.

Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme.

H. Tai, C. Ensor, 1991, Biochemical and biophysical research communications.

Thromboxanes: synthase and receptors.

H. Tai, R. Shen, 1998, Journal of biomedical science.

L. Muglia, H. Tai, Kikuko Watanabe, 2022 .

The porcine thromboxane synthase-encoding cDNA: sequence, mRNA expression and enzyme production in Sf9 insect cells.

H. Tai, S. Baek, L. Zhang, 1994, Gene.

Altered hepatic eicosanoid concentrations in rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid

M. Wilson, H. Tai, L. Robertson, 2009, Archives of Toxicology.

NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase Regulates Levels of Bioactive Lipids in Non–Small Cell Lung Cancer

R. Yantiss, M. Mazumdar, S. Markowitz, 2008, Cancer Prevention Research.

Alteration of platelet activating factor (PAF) metabolism in rat pulmonary alveolar macrophages and plasma by cigarette smoking.

H. Tai, T. Ichimaru, 1992, Prostaglandins, leukotrienes, and essential fatty acids.

Oxidoreductases in Lipoxin A4 Metabolic Inactivation

B. Levy, C. Clish, H. Tai, 2000, The Journal of Biological Chemistry.

Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA.

C. Clish, H. Tai, T. Takano, 1998, The Journal of pharmacology and experimental therapeutics.

Development of radioimmunoassay for thromboxane B2.

H. Tai, B. Yuan, 1978, Analytical biochemistry.

Metabolism of Prostaglandin Glycerol Esters and Prostaglandin Ethanolamides in Vitro and in Vivo *

J. Morrow, L. Marnett, H. Tai, 2001, The Journal of Biological Chemistry.

Expression and site-directed mutagenesis of mouse prostaglandin E2 receptor EP3 subtype in insect cells.

H. Tai, C. Huang, 1995, The Biochemical journal.

Prostaglandin catabolizing enzymes.

H. Tai, Huiping Zhou, M. Tong, 2002, Prostaglandins & other lipid mediators.

Stimulation of 12-lipoxygenase activity in rat platelets by 17β-estradiol

S. Murota, H. Tai, H. Orimo, 1982 .

Agonist-induced lipoxin A4 generation: Detection by a novel lipoxin A4-ELISA

E. Israel, J. Drazen, B. Levy, 1993, Lipids.

Stimulation of prostaglandin E2 synthesis by interleukin-1beta is amplified by interferons but inhibited by interleukin-4 in human amnion-derived WISH cells.

H. Tai, Z. Wang, L. Harding, 1996, Biochimica et biophysica acta.

Cloning and expression of the cDNA for rat NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.

H. Tai, H. Zhou, H. Zhang, 1997, Gene.

Intramolecular ADP-ribose transfer reactions and calcium signalling. Potential role of 2'-phospho-cyclic ADP-ribose in oxidative stress.

H. Tai, E. Jacobson, M. Jacobson, 1997, Advances in experimental medicine and biology.

Simultaneous radioimmunoassay of Secretin and gastrin.

H. Tai, W. Chey, 1976, Analytical biochemistry.

Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells.

H. Tai, M. Tong, Yunfei Ding, 2006, Carcinogenesis.

Polyamine and prostaglandin markers in focal cerebral ischemia.

H. Tai, R. Dempsey, J. W. Olson, 1985, Neurosurgery.

Expression of rat steroid 5α-reductase (isozyme-1) in Spodoptera Frugiperda, SF21, insect cells: Expression of rat steroid 5α-reductase

H. Tai, A. Bhattacharyya, N. Chiang, 1997, Steroids.

Hypoxia provokes leukotriene-dependent neutrophil sequestration in perfused rabbit hearts.

H. Tai, M. Gillespie, M. Jay, 1987, The Journal of pharmacology and experimental therapeutics.

Stimulation of cyclic nucleotide phosphodiesterase by products of phosphatidylinositol metabolism catalyzed by phospholipase A2.

H. Tai, C. Tai, 1982, Archives of biochemistry and biophysics.

Leukotriene B4 Release and Polymorphonuclear Cell Infiltration in Spinal Cord Injury

P. Perot, H. Tai, E. Hogan, 1990, Journal of neurochemistry.

Development of cyclooxygenase and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia.

H. Tai, R. Dempsey, K. Meyer, 1986, Journal of neurosurgery.

Monoglyceride and diglyceride lipases from human platelet microsomes.

H. Tai, L. Chau, 1988, Biochimica et biophysica acta.

Diglyceride/monoglyceride lipases pathway is not essential for arachidonate release in thrombin-activated human platelets.

H. Tai, L. Chau, 1983, Biochemical and biophysical research communications.

Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function.

G. Weissmann, H. Tai, S. Hoffstein, 1974, The Journal of clinical investigation.

Platelet-activating factor raises airway and vascular pressures and induces edema in lungs perfused with platelet-free solution.

H. Tai, T. Saga, M. Mojarad, 2015, The American review of respiratory disease.

Development of radioimmunoassay for motilin.

H. Tai, W. Chey, 1978, Analytical biochemistry.

Radioimmunoassay of vasoactive intestinal polypeptide.

H. Tai, W. Chey, T. Chang, 1979, Analytical biochemistry.

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

L. Muglia, H. Tai, M. Asada, 2008, Molecular endocrinology.

Prostaglandin catabolic enzymes as tumor suppressors

H. Tai, 2011, Cancer and Metastasis Reviews.

Oxygen radicals in the nonvagal component of noncholinergic airway constriction.

H. Tai, Y. Lai, H. Q. Zhang, 1996, Respiration physiology.

Age-dependent mechanism in guinea pig bronchoconstriction induced by exsanguination.

H. Tai, Y. Lai, H. Q. Zhang, 1995, Respiration physiology.

Abnormal platelet response to thromboxane A2

H. Tai, 2018 .

Activation of extracellular signal-regulated kinase by 12-hydroxyheptadecatrienoic acid in prostate cancer PC3 cells.

H. Tai, Xiuling Li, Jingyan Wei, 2007, Archives of biochemistry and biophysics.

Thromboxanes: Synthase and Receptors

H. Tai, R. Shen, 1998, Journal of Biomedical Science.

Quantitation of 13-hydroxyoctadecadienoic acid (13-HODE) by radioimmunoassay.

H. Tai, Y. Tonogai, 1990, Prostaglandins, leukotrienes, and essential fatty acids.

Alterations of arachidonate metabolism in cardiovascular system by cigarette smoking.

H. Tai, S. Fukuda, W. Chang, 1990, Advances in experimental medicine and biology.

Changes in arachidonate metabolism in aortas and platelets in aging rats.

H. Tai, W. Chang, 1983, Prostaglandins, leukotrienes, and medicine.

Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.

H. Tai, H. Tanizawa, 1990, Prostaglandins, leukotrienes, and essential fatty acids.

Phorbol ester induces inhibition of arachidonate incorporation into phospholipids in human neutrophils.

H. Tai, H. Yamazaki, 1990, Prostaglandins, leukotrienes, and essential fatty acids.

A sensitive and specific radioimmunoassay for platelet-activating factor

H. Tai, Chang-jin Wang, 1992, Lipids.

A facile synthesis of an aldehydic analog of platelet activating factor and its use in the production of specific antibodies.

H. Tai, C. Wang, 1990, Chemistry and physics of lipids.

Synthesis and SAR of thiazolidinedione derivatives as 15-PGDH inhibitors.

Hoon Cho, H. Tai, Ying Wu, 2010, Bioorganic & medicinal chemistry.

12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT) is an excellent substrate for NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.

H. Tai, R. Shen, Y. Liu, 1985, Biochemical and biophysical research communications.

Stimulations of arachidonate release and inositol-1,4,5-triphosphate formation are mediated by distinct G-proteins in human platelets.

H. Tai, I. Fuse, 1987, Biochemical and biophysical research communications.

Pioglitazone and Rosiglitazone Decrease Prostaglandin E2 in Non–Small-Cell Lung Cancer Cells by Up-Regulating 15-Hydroxyprostaglandin Dehydrogenase

H. Tai, S. Dubinett, Sherven Sharma, 2007, Molecular Pharmacology.

Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD−/−) mice due to requirement for embryo 15-HPGD activity

L. Muglia, H. Tai, M. Asada, 2019, Scientific Reports.

Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets?

H. Tai, I. Fuse, 1988, Biochimica et biophysica acta.

Enzymatic synthesis of (15s)-[15-3h]prostaglandins and their use in the development of a simple and sensitive assay for 15-hydroxyprostaglandin dehydrogenase.

H. Tai, 1976, Biochemistry.

Selective inhibition of 5-lipoxygenase pathway in rat pulmonary alveolar macrophages by cigarette smoking.

H. Tai, T. Iwanaga, C. Tai, 1987, Biochimica et biophysica acta.

Differential changes in 15-hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium.

H. Tai, S. Lye, J. Challis, 2002, The Journal of clinical endocrinology and metabolism.

Characterization of the genomic structure and promoter of the mouse NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene.

H. Tai, C. Ensor, M. Matsuo, 1997, Biochemical and biophysical research communications.

Immunohistochemical localization, messenger ribonucleic acid abundance, and activity of 15-hydroxyprostaglandin dehydrogenase in placenta and fetal membranes during term and preterm labor.

H. Tai, J. Challis, C. Ensor, 1994, The Journal of clinical endocrinology and metabolism.

Immunocytochemical distribution and localization of 15-hydroxyprostaglandin dehydrogenase in human fetal membranes, decidua, and placenta.

H. Tai, J. Challis, S. Riley, 1990, American journal of obstetrics and gynecology.

NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase: immunochemical characterization of the lung enzyme from pregnant rabbits.

R. Markwald, H. Tai, J. Okita, 1990, Archives of biochemistry and biophysics.

Interleukin-1 beta and dexamethasone regulate gene expression of prostaglandin H synthase-2 via the NF-kB pathway in human amnion derived WISH cells.

H. Tai, Z. Wang, 1998, Prostaglandins, leukotrienes, and essential fatty acids.

Activation of thromboxane receptor alpha induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells.

H. Tai, Wen-Chang Chang, Xiuling Li, 2007, Biochemical pharmacology.

Serine 331 is the major site of receptor phosphorylation induced by agents that activate protein kinase G in HEK 293 cells overexpressing thromboxane receptor alpha.

H. Tai, H. Zhou, S. Yamamoto, 2001, Archives of biochemistry and biophysics.

Regulation of synthesis and activity of NAD(+)-dependent 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) by dexamethasone and phorbol ester in human erythroleukemia (HEL) cells.

H. Tai, C. Ensor, C. Xun, 1991, Biochemical and biophysical research communications.

Cigarette smoking stimulates lipoxygenase but not cyclooxygenase pathway in platelets.

H. Tai, S. Fukuda, W. Chang, 1983, Biochemical and biophysical research communications.

Anti-inflammatory pharmacology and mechanism of the orally active capsaicin analogs, NE-19550 and NE-28345

H. Tai, R. Fanelli, C. Chiabrando, 1990, Agents and Actions.

Cyclic AMP response element mediates dexamethasone induced suppression of prostaglandin H synthase-2 gene expression in human amnion derived WISH cells.

H. Tai, Z. Wang, 1999, Prostaglandins, leukotrienes, and essential fatty acids.

Characterization of (5Z)-7-[3-endo-[(4-iodophenylsulfonyl) amino] -bicyclo[2.2.1]hep-2-exo-yl]heptenoic acid (IS-145) as an antagonist for the study of thromboxane A2 receptor.

H. Tai, W. Kan, W. M. Kan, 1993, Prostaglandins, leukotrienes, and essential fatty acids.

Gossypol, a potent inhibitor of arachidonate 5- and 12-lipoxygenases.

H. Tai, Y. Hamasaki, 1985, Biochimica et biophysica acta.

Changes in prostacyclin and thromboxane biosynthesis and their catabolic enzyme activity in kidneys of aging rats.

H. Tai, W. Chang, 1984, Life sciences.

Increase in thromboxane B2 and decrease in prostaglandin E2 and 6-keto-prostaglandin F1 alpha release into rat bronchoalveolar fluid as a consequence of cigarette smoking.

H. Tai, T. Iwanaga, H. Tanizawa, 1987, Prostaglandins, leukotrienes, and medicine.

Abnormal platelet response to thromboxane A2.

H. Tai, G. L. Le Breton, K. Wu, 1981, The Journal of clinical investigation.

Purification and characterization of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney.

H. Tai, O. Mak, Y. Liu, 1990, Biochimica et biophysica acta.

Phosphorylation and desensitization of the human thromboxane receptor-alpha by G protein-coupled receptor kinases.

H. Tai, H. Zhou, F. Yan, 2001, The Journal of pharmacology and experimental therapeutics.

Characterization of two enzyme proteins catalyzing NADP+/NADPH-dependent oxidoreduction of prostaglandins at C-9 and C-15 from swine kidney.

H. Tai, D. Chang, 1982, Archives of biochemistry and biophysics.

Expression of the cDNA for NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase as a catalytically active enzyme in Escherichia coli.

H. Tai, C. Ensor, 1992, Prostaglandins, leukotrienes, and essential fatty acids.

Interleukin-4 up-regulates 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in human lung cancer cells.

H. Tai, X. Chi, 2010, Experimental cell research.

Calcium stimulation of a novel 12-lipoxygenase from rat basophilic leukemia (RBL-1) cells.

H. Tai, Y. Hamasaki, 1984, Biochimica et biophysica acta.

Photoaffinity labeling of NAD(+)-linked enzymes.

H. Tai, C. Ensor, 1997, Methods in enzymology.

Transformation of arachidonate into 6-oxoprostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 by sheep lung microsomal fraction.

H. Tai, A. Wu, B. Yuan, 1978, The Biochemical journal.

Intracellular translocation of rap 1-B G-protein induced by prostaglandin E1 is blocked by phorbol ester in human platelets.

H. Tai, H. Tau, 1994, Prostaglandins, leukotrienes, and essential fatty acids.

Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester.

H. Tai, S. Lo, K. Wu, 1988, The Journal of biological chemistry.

Selective inhibition of thromboxane synthetase by pyridine and its derivatives.

H. Tai, C. Tai, N. Lee, 1980, Archives of biochemistry and biophysics.

[17] Assay of thromboxane a synthase inhibitors☆

H. Tai, 1982 .

Radioimmunological assay of prostacyclin synthetase activity.

H. Tai, C. Tai, 1980, Prostaglandins and medicine.

Studies on the thromboxane synthesizing system in human platelet microsomes.

H. Tai, B. Yuan, 1978, Biochimica et biophysica acta.

NAD+-linked 15-hydroxyprostaglandin dehydrogenase: structure and biological functions.

H. Tai, M. Tong, H. Cho, 2006, Current pharmaceutical design.

Immunoaffinity purification and characterization of thromboxane synthase from porcine lung.

H. Tai, R. Shen, 1986, The Journal of biological chemistry.

Pharmacologic effects and detection methods of methylated analogs of fentanyl in horses.

H. Tai, T. Tobin, W. E. Woods, 1989, American journal of veterinary research.

Cloning and expression of the cDNA for mouse NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.

H. Tai, C. Ensor, M. Matsuo, 1996, Biochimica et biophysica acta.

Elevated thromboxane B2 levels in periodontal disease.

H. Tai, B. Rifkin, 1981, Journal of periodontal research.

Glycogen Synthase Kinase-3 Phosphorylation, T-Cell Factor Signaling Activation, and Cell Morphology Change following Stimulation of Thromboxane Receptor α

H. Tai, Weili Yan, 2006, Journal of Pharmacology and Experimental Therapeutics.

AN 125I‐LABELED N6‐SUBSTITUTED AZIDO ANALOG OF NAD+ FOR THE PHOTOAFFINITY LABELING OF NAD+‐LINKED ENZYMES

H. Tai, C. Ensor, P. Chen, 1994, Photochemistry and photobiology.

Synthesis and biological evaluation of novel thiazolidinedione analogues as 15-hydroxyprostaglandin dehydrogenase inhibitors.

C. Jang, Hoon Cho, H. Tai, 2011, Journal of medicinal chemistry.

Formation of Prostaglandins E2 and D2 via the Isoprostane Pathway

J. Morrow, S. Dey, H. Tai, 2003, Journal of Biological Chemistry.

Characterization of recombinant human CXCR4 in insect cells: role of extracellular domains and N-glycosylation in ligand binding.

H. Tai, H. Zhou, H. Zhou, 1999, Archives of biochemistry and biophysics.

NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney. I. Purification and partial characterization.

H. Tai, D. T. Kung-Chao, Hsin-Hsiung Tai, 1980, Biochimica et biophysica acta.

Urinary Prostaglandin F2α Is Generated from the Isoprostane Pathway and Not the Cyclooxygenase in Humans*

J. Morrow, H. Tai, H. Yin, 2007, Journal of Biological Chemistry.

On the inhibitory potency of imidazole and its derivatives on thromboxane synthetase.

H. Tai, B. Yuan, 1978, Biochemical and biophysical research communications.

A simple and sensitive assay for 9-hydroxyprostaglandin dehydrogenase.

H. Tai, B. Yuan, 1977, Analytical Biochemistry.

Purification and assay of 9-hydroxyprostaglandin dehydrogenase from rat kidney.

H. Tai, B. Yuan, 1982, Methods in enzymology.

Assay of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase using (15S)-[15-3H]PGE2.

H. Tai, 1982, Methods in enzymology.

Metabolism of prostaglandins in spontaneously hypertensive rats: NAD"-dependent 15-hydroxyprostaglandin dehydrogenase activity is decreased in kidney and increased in lung.

H. Tai, M. Sun, B. Yuan, 1979, Life sciences.

Regulation of prostaglandin metabolism: activation of 15-hydroxyprostaglandin dehydrogenase by chlorpromazine and imipramine related drugs.

H. Tai, C. Hollander, 1976, Biochemical and biophysical research communications.

Enzyme immunoassay of two nicergoline metabolites, 10 alpha-methoxy-9, 10-dihydrolysergol (MDL) and 1-methyl-10 alpha-methoxy-9, 10-dihydrolysergol (MMDL).

H. Tai, G. Digenis, Z. Tian, 1996, Research communications in molecular pathology and pharmacology.

Release of arachidonate from diglyceride in human platelets requires the sequential action of a diglyceride lipase and a monoglyceride lipase.

H. Tai, L. Chau, 1981, Biochemical and biophysical research communications.

High-sensitivity radioimmunoassay screening method for fentanyl.

H. Tai, T. Tobin, T. Wood, 1986, American journal of veterinary research.

Activation of thromboxane A(2) receptors induces orphan nuclear receptor Nurr1 expression and stimulates cell proliferation in human lung cancer cells.

H. Tai, Xiuling Li, 2009, Carcinogenesis.

Expression and Stimulates Cell Proliferation in Human Lung Cancer Cells

H. Tai, Xiuling Li, 2009 .

Mechanism of prostaglandin biosynthesis in rabbit kidney medulla. A rate-limiting step and the differential stimulatory actions of L-adrenaline and glutathione.

H. Tai, 1976, The Biochemical journal.

Biosynthesis of prostaglandins in rabbit kidney medulla. Properties of prostaglandin synthase.

H. Tai, C. Hollander, C. Tai, 1976, The Biochemical journal.

Prostaglandin 9-ketoreductase and type II 15-hydroxyprostaglandin dehydrogenase from swine kidney are alternate activities of a single enzyme protein.

H. Tai, M. Sun, D. Chang, 1981, Biochemical and biophysical research communications.

NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney. I. Purification and partial characterization.

H. Tai, D. T. Kung-Chao, 1980, Biochimica et biophysica acta.

9-Hydroxyprostaglandin dehydrogenase from rat kidney. Purification to homogeneity and partial characterization.

H. Tai, B. Yuan, C. Tai, 1980, The Journal of biological chemistry.

Identification of metabolites of azaperone in horse urine.

R. Sams, H. Tai, D. Watt, 1996, Journal of pharmaceutical sciences.

Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase.

K. Black, H. Tai, H. Koeffler, 2008, Cancer research.

Plasma secretin concentrations in fasting and postprandial state in man

H. Tai, W. Chey, Y. H. Lee, 1978, The American Journal of Digestive Diseases.

Observations on plasma secretion levels by radioimmunoassay in response to duodenal acidification and to a meat meal in humans

H. Tai, W. Chey, Ross A. Rhodes, 1976, The American Journal of Digestive Diseases.

Restoration of leukotriene B(4)-12-hydroxydehydrogenase/15- oxo-prostaglandin 13-reductase (LTBDH/PGR) expression inhibits lung cancer growth in vitro and in vivo.

H. Tai, M. Tong, Jingyan Wei, 2010, Lung cancer.

Induction of NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase expression by androgens in human prostate cancer cells.

H. Tai, M. Tong, 2000, Biochemical and biophysical research communications.

Differential production of prostaglandin E(2) in male and female mice subjected to thermal injury contributes to the gender difference in immune function: possible role for 15-hydroxyprostaglandin dehydrogenase.

H. Tai, D. E. Faunce, E. Kovacs, 2000, Cellular immunology.

14-3-3ζ interacts with human thromboxane receptors and is involved in the agonist-induced activation of the extracellular-signal-regulated kinase

H. Tai, Weili Yan, Yunfei Ding, 2006 .

Induction of a decrease in renal NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity by estradiol in rats.

H. Tai, W. Chang, 1985, Biochemical pharmacology.

Radioimmunoassay of motilin

H. Tai, W. Chey, H. Yajima, 1978, The American Journal of Digestive Diseases.

Rapid extraction of secretin from plasma by XAD-2 resin and its application in the radioimmunoassay of secretin.

H. Tai, W. Chey, 1978, Analytical biochemistry.

Plasma secretin and gastrin responses to a meat meal and duodenal acidification in dogs.

H. Tai, W. Chey, K. Lee, 1976, The American journal of physiology.

Effects of testosterone on the metabolism of arachidonic acid by aortas and platelets in rats.

S. Murota, H. Tai, J. Nakao, 1982, Prostaglandins, leukotrienes, and medicine.

Computational redesign of human butyrylcholinesterase for anticocaine medication.

Guangfu Yang, Chang-Guo Zhan, D. Gao, 2005, Proceedings of the National Academy of Sciences of the United States of America.

15-Hydroxyprostaglandin Dehydrogenase Is Down-regulated in Gastric Cancer

O. Monni, C. Haglund, A. Ristimäki, 2009, Clinical Cancer Research.

Inactivation of pulmonary NAD+-dependent 15-hydroxyprostaglandin dehydrogenase by acrolein.

H. Tai, Y. Liu, 1985, Biochemical pharmacology.

Most efficient cocaine hydrolase designed by virtual screening of transition states.

Fang Zheng, Chang-Guo Zhan, D. Gao, 2008, Journal of the American Chemical Society.

Localization of 15-hydroxy prostaglandin dehydrogenase in human fetal membranes, decidua, and placenta during pregnancy.

H. Tai, J. Challis, S. Riley, 1992, Gynecologic and obstetric investigation.

Prostaglandin 9-ketoreductase/type II 15-hydroxyprostaglandin dehydrogenase is not a prostaglandin specific enzyme.

H. Tai, D. Chang, 1981, Biochemical and biophysical research communications.

Photoaffinity labeling of human placental NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase with [alpha-32P]2N3NAD+. Identification of a peptide in the adenine ring binding domain.

H. Tai, C. Ensor, B. Haley, 1993, Journal of Biological Chemistry.

Oxidoreductases in Lipoxin A4 Metabolic Inactivation. A Novel Role for 15-oxoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in Inflammation

B. Levy, C. Clish, H. Tai, 2000 .

Threonine 188 is critical for interaction with NAD+ in human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.

H. Tai, H. Zhou, H Zhou, 1999, Biochemical and biophysical research communications.

15-Hydroxyprostaglandin dehydrogenase.

H. Tai, C. Ensor, 1995, Journal of lipid mediators and cell signalling.

Thromboxane receptor alpha mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells.

H. Tai, Xiuling Li, Jingyan Wei, 2010, Lung cancer.

Inhibition of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by cyclooxygenase inhibitors and chemopreventive agents.

H. Tai, H. Cho, 2002, Prostaglandins, leukotrienes, and essential fatty acids.

Cloning and sequence analysis of the cDNA for human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.

H. Tai, R. Okita, C. Ensor, 1990, The Journal of biological chemistry.

Thromboxane A2 receptor‐mediated release of matrix metalloproteinase‐1 (MMP‐1) induces expression of monocyte chemoattractant protein‐1 (MCP‐1) by activation of protease‐activated receptor 2 (PAR2) in A549 human lung adenocarcinoma cells

H. Tai, Xiuling Li, 2014, Molecular carcinogenesis.

Design, Preparation, and Characterization of High-Activity Mutants of Human Butyrylcholinesterase Specific for Detoxification of Cocaine

C. Zhan, H. Tai, F. Zheng, 2011, Molecular Pharmacology.

Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase.

A. Hamza, C. Zhan, H. Tai, 2005, Archives of biochemistry and biophysics.

Expression and functional characterization of mutant human CXCR4 in insect cells: role of cysteinyl and negatively charged residues in ligand binding.

H. Tai, H. Zhou, H Zhou, 2000, Archives of biochemistry and biophysics.

15-Hydroxyprostaglandin dehydrogenase can be induced by dexamethasone and other glucocorticoids at the therapeutic level in A549 human lung adenocarcinoma cells.

H. Tai, M. Tong, 2005, Archives of biochemistry and biophysics.

Agents that elevate cyclic AMP induce receptor phosphorylation primarily at serine 331 in HEK 293 cells overexpressing human thromboxane receptor alpha.

H. Tai, Huiping Zhou, Fengxiang Yan, 2002, Biochemical pharmacology.

Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer.

D. Carbone, H. Tai, D. Billheimer, 2007, Cancer research.

Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha.

S. Dey, H. Tai, K. Subbaramaiah, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Purification, cDNA cloning and expression of 15-oxoprostaglandin 13-reductase from pig lung.

H. Tai, H. Zhang, H H Tai, 1998, The Biochemical journal.

Stimulation of 12-lipoxygenase activity in rat platelets by 17 beta-estradiol.

S. Murota, H. Tai, H. Orimo, 1982, Biochemical pharmacology.

Induction of fatty acid cyclooxygenase in rat aortic smooth muscle cells by estradiol.

S. Murota, H. Tai, J. Nakao, 1983, Prostaglandins, leukotrienes, and medicine.

Prostaglandin E2 alterations during sepsis are partially mediated by endotoxin-induced inhibition of prostaglandin 15-hydroxydehydrogenase.

R. Gamelli, H. Tai, J. Ricken, 1997, The Journal of trauma.

Phenylalanine 138 in the second intracellular loop of human thromboxane receptor is critical for receptor-G-protein coupling.

H. Tai, H. Zhou, S. Yamamoto, 1999, Biochemical and biophysical research communications.

Synergistic stimulation of thromboxane biosynthesis by calcium ionophore and phorbol ester or thrombin in human platelets.

H. Tai, A. Mobley, 1985, Biochemical and biophysical research communications.

Monoclonal anti-idiotypic antibody to a potent thromboxane A2 receptor antagonist and its interaction with thromboxane A2 receptor.

H. Tai, W. Kan, 1993, The Journal of biological chemistry.

Streptococcus pneumoniae-induced alterations in levels of circulating thromboxane and prostacyclin: dissociation from granulocytopenia, thrombocytopenia, and pulmonary leukostasis.

H. Tai, S. Goldblum, K. M. Wu, 1986, The Journal of infectious diseases.

Purification of thromboxane synthetase and evidence of two distinct mechanisms for the formation of 12-L-hydroxy-5,8,10-heptadecatrienoic acid by porcine lung microsomes.

H. Tai, E. Hall, 1981, Biochimica et biophysica acta.

Monoclonal anti-idiotypic antibodies to platelet activating factor (PAF) and their interaction with PAF receptors.

H. Tai, C. Wang, 1991, The Journal of biological chemistry.

Impairment of secretin release in celiac sprue

H. Tai, W. Chey, Ross A. Rhodes, 1978, The American Journal of Digestive Diseases.

Morphine and etorphine: XIV. Detection by ELISA in equine urine.

H. Tai, D. Watt, S. Stanley, 1991, Journal of analytical toxicology.

Non-isotopic immunoassay drug tests in racing horses: a review of their application to pre- and post-race testing, drug quantitation, and human drug testing.

H. Tai, D. Watt, T. Tobin, 1988, Research communications in chemical pathology and pharmacology.

Pulmonary NAD+-linked 15-hydroxyprostaglandin dehydrogenase activity is decreased by cigarette smoking.

H. Tai, S. Fukuda, W. Chang, 1984, Life sciences.

Purification and characterization of an NAD(+)-dependent dehydrogenase that catalyzes the oxidation of thromboxane B2 at C-11 from porcine liver. Development and application of 11-dehydro-thromboxane B2 radioimmunoassay to enzyme assay.

H. Tai, P. Wu, M. Fritzo, 1990, Biochimica et biophysica acta.

Phorbol ester, 1,2-diacylglycerol, and collagen induce inhibition of arachidonic acid incorporation into phospholipids in human platelets.

H. Tai, I. Fuse, T. Iwanaga, 1989, The Journal of biological chemistry.

Purification and characterization of phosphatidylinositol kinase from porcine liver microsomes.

H. Tai, Z. Zhang, W. Hou, 1988, Biochimica et biophysica acta.

Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells.

H. Tai, M. Tong, Yunfei Ding, 2006, Biochemical pharmacology.

The Escherichia coli-derived Fab fragment of the IgM/kappa antibody IN-1 recognizes and neutralizes myelin-associated inhibitors of neurite growth.

M. Schwab, C. Bandtlow, H. Tai, 1996, European journal of biochemistry.

Cloning, Expression and Site-Directed Mutagenesis of the cDNA for Human Placental NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase

H. Tai, C. Ensor, 1991 .

Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).

H. Tai, M. Tong, X. Chi, 2011, Prostaglandins & other lipid mediators.

Inhibition of thromboxane synthesis and platelet aggregation by pyridine and its derivatives.

H. Tai, C. Tai, N. Lee, 1980, Advances in prostaglandin and thromboxane research.

Increase in enzyme activities of prostaglandin biosynthesis and catabolism by acute ureteral ligation in rat kidney.

H. Tai, S. Fukuda, Y. Hamasaki, 1985, Life sciences.

A radioimmunoassay for prostaglandin endoperoxide synthetase.

H. Tai, C. Tai, 1984, Prostaglandins, leukotrienes, and medicine.

Group B Streptococcus Promotes Oxygen Radical-Dependent Thromboxane Accumulation in Young Piglets

H. Tai, B. Bowdy, S. Marple, 1990, Pediatric Research.

Cigarette smoke-induced alterations in the release of arachidonate metabolites by pulmonary alveolar macrophage from selenium-fed and selenium-deficient rats.

H. Tai, C. Gairola, 1986, Biochemical pharmacology.

Rubber additives inhibit the calcium ionophore and thrombin induced activation of rabbit platelets

H. Tai, A. Yamauchi, Takako Yamaguchi, 1991 .

Thiazolidinediones as a novel class of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

H. Tai, Hoon Cho, 2002, Archives of biochemistry and biophysics.

Molecular dynamics simulation of cocaine binding with human butyrylcholinesterase and its mutants.

Chang-Guo Zhan, Adel Hamza, A. Hamza, 2005, The journal of physical chemistry. B.

Computational design of a human butyrylcholinesterase mutant for accelerating cocaine hydrolysis based on the transition-state simulation.

Guangfu Yang, Chang-Guo Zhan, D. Gao, 2006, Angewandte Chemie.

Bacterial expression and site-directed mutagenesis of two critical residues (tyrosine-151 and lysine-155) of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.

H. Tai, H H Tai, C. Ensor, 1994, Biochimica et biophysica acta.

Hypoxia stimulates prostacyclin generation by dog lung in vitro.

H. Tai, S. Said, Y. Hamasaki, 1982, Prostaglandins, leukotrienes, and medicine.

A radioimmunoassay for 6-ketoprostaglandin E1.

H. Tai, D. Chang, 1982, Prostaglandins Leukotrienes and Medicine.

Butyric acid enhances cyclooxygenase activity in rat basophilic leukemia 2H3 cells.

H. Tai, S. Miyazaki, Y. Hamasaki, 1988, Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society.

Regulatory mechanism of arachidonic acid metabolism in rat basophilic leukemia (RBL)-2H3 cells.

H. Tai, S. Miyazaki, Y. Hamasaki, 1987, Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society.

Burn injury with infection alters prostaglandin E2 synthesis and metabolism.

R. Gamelli, H. Tai, E. Hahn, 1998, The Journal of trauma.

Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.

H. Tai, Hoon Cho, M. Oliveira, 2003, Archives of biochemistry and biophysics.

Monoclonal antibodies to thromboxane synthase from porcine lung. Production and application to development of a tandem immunoradiometric assay.

H. Tai, R. Shen, 1986, Journal of Biological Chemistry.

Synthesis of [5,6-3H]arachidonic acid and its use in development of a sensitive assay for prostacyclin synthetase.

H. Tai, C. Sih, C. T. Hsu, 1980, Biochemistry.

Assay of prostacyclin synthase using [5,6-3H]PGH2.

H. Tai, C. Sih, 1982, Methods in Enzymology.

Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

K. Bae, J. Sanabria, L. Kasturi, 2015, Science.

Expression of two different forms of cDNA for thromboxane synthase in insect cells and site-directed mutagenesis of a critical cysteine residue.

H. Tai, S. Baek, R. Shen, 1993, The Biochemical journal.

Partial characterization of a low-molecular-weight, macrophage-derived inhibitor of DNA synthesis: a possible immunoregulatory molecule.

H. Tai, D. Coleman, R. Evans, 1989, Cellular immunology.

Design, Preparation, and Characterization of High-Activity Mutants of Human Butyrylcholinesterase Specific for Detoxification of Cocaine

C. Zhan, H. Tai, F. Zheng, 2011, Molecular Pharmacology.

Most efficient cocaine hydrolase designed by virtual screening of transition states.

D. Gao, C. Zhan, H. Tai, 2008, Journal of the American Chemical Society.

Site-directed mutagenesis studies of the NADPH-binding domain of rat steroid 5alpha-reductase (isozyme-1) I: analysis of aromatic and hydroxylated amino acid residues.

H. Tai, A. Bhattacharyya, D. Collins, 1999, Steroids.

Purification of NADP+/NADPH-dependent 15-hydroxyprostaglandin dehydrogenase and prostaglandin 9-ketoreductase from porcine kidney.

H. Tai, D. Chang, 1982, Methods in enzymology.