I. Cristea

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The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome

B. Chait, M. Niepel, M. Rout, 2013, Molecular biology of the cell.

Proteomics and integrative omic approaches for understanding host–pathogen interactions and infectious diseases

I. Cristea, Pierre M. Jean Beltran, Joel D. Federspiel, 2017, Molecular systems biology.

Proteomic approaches to uncovering virus–host protein interactions during the progression of viral infection

I. Cristea, K. Lum, 2016, Expert review of proteomics.

Protein interactions and consensus clustering analysis uncover insights into herpesvirus virion structure and function relationships

M. Topf, I. Cristea, B. Vollmer, 2019, PLoS biology.

A Proteomic Perspective of Sirtuin 6 (SIRT6) Phosphorylation and Interactions and Their Dependence on Its Catalytic Activity*

I. Cristea, Y. Miteva, 2013, Molecular & Cellular Proteomics.

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

S. Rafii, D. Zheng, Scott B. Dewell, 2010, Cell.

Consensus clustering of herpesvirus protein interaction networks provides insights into their evolutionary relationship with bacteriophages

M. Topf, I. Cristea, B. Vollmer, 2018, bioRxiv.

Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA

I. Cristea, K. Lum, Timothy R Howard, 2019, mBio.

Research on The Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, according to the HUPO Human Proteome Project.

Eric W. Deutsch, Nuno Bandeira, Ruedi Aebersold, 2020, Journal of proteome research.

A proteomic investigation of drug-induced steatosis in rat liver.

R. Mortishire-Smith, G. Meneses‐Lorente, I. Cristea, 2004, Chemical research in toxicology.

Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection

I. Cristea, X. Sheng, Yutaka Hashimoto, 2020, Nature Communications.

Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective

I. Cristea, Timothy R Howard, Timothy R. Howard, 2020, Biomolecules.

S. Gygi, M. Rezaeian, R. Martins, 2017, Scientific Reports.

Human Sirtuin 2 Localization, Transient Interactions, and Impact on the Proteome Point to Its Role in Intracellular Trafficking*

I. Cristea, Hanna G. Budayeva, 2016, Molecular & Cellular Proteomics.

The Emerging Role of Nuclear Viral DNA Sensors*

Ileana M Cristea, I. Cristea, K. Lum, 2015, The Journal of Biological Chemistry.

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection

D. C. Hancks, I. Cristea, D. Knipe, 2015, Proceedings of the National Academy of Sciences.

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA

I. Cristea, T. Greco, Jennifer Wang, 2015, Molecular systems biology.

A mass spectrometry view of stable and transient protein interactions.

I. Cristea, Hanna G. Budayeva, 2014, Advances in experimental medicine and biology.

Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor.

Manuel Llinás, Ileana M Cristea, Philipp Ross, 2017, Cell host & microbe.

Conservation and divergence of protein pathways in the vertebrate heart

Laura E. Herring, F. Conlon, I. Cristea, 2019, PLoS biology.

Systematic profiling of protein complex dynamics reveals DNA-PK phosphorylation of IFI16 en route to herpesvirus immunity

Joshua L. Justice, I. Cristea, Dawei Liu, 2021, Science Advances.

Subcellular proteomics

A. Emili, A. Gingras, L. Foster, 2021, Nature Reviews Methods Primers.

A TRUSTED targeted mass spectrometry assay for pan-herpesvirus protein detection

Jesse H. Arbuckle, I. Cristea, Joel D. Federspiel, 2022, Cell reports.

A proteomics perspective on viral DNA sensors in host defense and viral immune evasion mechanisms.

I. Cristea, Aaron Javitt, Marni S. Crow, 2015, Journal of molecular biology.

Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA.

I. Cristea, Pierre M. Jean Beltran, Joel D. Federspiel, 2020, Cell reports.

Nuclear antiviral innate responses at the intersection of DNA sensing and DNA repair.

Joshua L. Justice, I. Cristea, 2022, Trends in microbiology.

HIV – host interactome revealed directly from infected cells

B. Chait, J. Binley, D. Fenyö, 2016 .

Affinity purification of protein complexes.

B. Chait, I. Cristea, 2011, Cold Spring Harbor protocols.

Stimulatory effects of advanced glycation endproducts (AGEs) on fibronectin matrix assembly.

I. Cristea, J. Schwarzbauer, T. Greco, 2017, Matrix biology : journal of the International Society for Matrix Biology.

Evidence for a Genetic and Physical Interaction between Nonstructural Proteins NS1 and NS4B That Modulates Replication of West Nile Virus

D. Fremont, M. Diamond, M. A. Edeling, 2012, Journal of Virology.

Tracking and Elucidating Alphavirus-Host Protein Interactions*

Ileana M Cristea, Brian T Chait, B. Chait, 2006, Journal of Biological Chemistry.

DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV‐1 infection

I. Cristea, T. Greco, A. Lin, 2015, Proteomics.

Immunoisolation of protein complexes from Xenopus.

F. Conlon, I. Cristea, T. Greco, 2012, Methods in molecular biology.

Host factors associated with the Sindbis virus RNA-dependent RNA polymerase : 1 a role for G 3 BP 1 and G 3 BP 2 in virus replication 2 3

B. Chait, C. Rice, M. Rout, 2010 .

The human cytomegalovirus protein pUL13 targets mitochondrial cristae architecture to increase cellular respiration during infection

I. Cristea, Pierre M. Jean Beltran, Joel D. Federspiel, 2021, Proceedings of the National Academy of Sciences.

Identification of Sirtuin4 (SIRT4) Protein Interactions: Uncovering Candidate Acyl-Modified Mitochondrial Substrates and Enzymatic Regulators.

I. Cristea, T. Greco, Rommel A Mathias, 2016, Methods in molecular biology.

K+ regulates relocation of Pellino‐2 to the site of NLRP3 inflammasome activation in macrophages

I. Cristea, O. Bruland, E. Rødahl, 2021, FEBS letters.

Virus integration : integration of the virus genome into host chromosomes INTEGRATION OF VIRAL GENOMES INTO HOST CELL

I. Cristea, V. Vogt, T. Greco, 2015 .

HTT-OMNI: A Web-based Platform for Huntingtin Interaction Exploration and Multi-omics Data Integration

I. Cristea, T. Greco, M. A. Kennedy, 2022, Molecular & cellular proteomics : MCP.

FIGURES FOR : A conserved coatomer-related complex containing Sec 13 and Seh 1 dynamically associates with the vacuole in Saccharomyces cerevisiae

Mark C. Field, B. Chait, A. Sali, 2011 .

Infection-Induced Peroxisome Biogenesis Is a Metabolic Strategy for Herpesvirus Replication.

O. Vitek, Cyril Galitzine, I. Cristea, 2018, Cell host & microbe.

Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa

B. Bassler, I. Cristea, T. Greco, 2022, bioRxiv.

The axonal sorting activity of pseudorabies virus Us9 protein depends on the state of neuronal maturation

Nikhila S Tanneti, L. Enquist, I. Cristea, 2020, bioRxiv.

The 2022 Report on the Human Proteome from the HUPO Human Proteome Project.

R. Aebersold, C. Lindskog, R. Moritz, 2022, Journal of proteome research.

Restructured membrane contacts rewire organelles for human cytomegalovirus infection

I. Cristea, S. Thompson, Katelyn C Cook, 2022, Nature Communications.

Intricate Roles of Mammalian Sirtuins in Defense against Viral Pathogens

I. Cristea, Hanna G. Budayeva, E. Rowland, 2015, Journal of Virology.

Syddansk Universitet Kinetics of nebivolol and its active metabolite after single dose oral administration of

I. Cristea, D. Muntean, L. Vlase, 2016 .

Kinetics of nebivolol and its active metabolite after single dose oral administration of nebivolol

I. Cristea, D. Muntean, L. Vlase, 2016 .

Peroxisome Plasticity at the Virus-Host Interface.

I. Cristea, Pierre M. Jean Beltran, Jorge A. Moreno, 2019, Trends in microbiology.

DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase.

I. Cristea, V. Zakian, Nasim Sabouri, 2012, Genes & development.

Influence of palladium(II) complexes on the cycloaddition of α-bromoalkyl ketenes to cyclopentadiene

J. M. Dickinson, I. Cristea, I. Fairlamb, 2001 .

Protein lipoylation: an evolutionarily conserved metabolic regulator of health and disease.

Ileana M Cristea, I. Cristea, Caroline K Snowden, 2018, Current opinion in chemical biology.

Sirtuin 4 Is a Lipoamidase Regulating Pyruvate Dehydrogenase Complex Activity

Ileana M. Cristea, Thomas Shenk, Yibin Kang, 2014, Cell.

Human Cytomegalovirus pUL83 Stimulates Activity of the Viral Immediate-Early Promoter through Its Interaction with the Cellular IFI16 Protein

B. Chait, M. Rout, I. Cristea, 2010, Journal of Virology.

The Proteomic Profile of Deleted in Breast Cancer 1 (DBC1) Interactions Points to a Multifaceted Regulation of Gene Expression*

Amanda J. Guise, I. Cristea, Pierre M. Jean Beltran, 2015, Molecular & Cellular Proteomics.

Running Title: Regulatory roles of DBC1 revealed by protein interactions

Amanda J. Guise, I. Cristea, P. Joshi, 2015 .

The CRAPome: a Contaminant Repository for Affinity Purification Mass Spectrometry Data

Amber L. Couzens, Mihaela E. Sardiu, Wade H. Dunham, 2013, Nature Methods.

A Functional Proteomics Perspective of DBC1 as a Regulator of Transcription.

I. Cristea, P. Joshi, S. S. Giguere, 2013, Journal of proteomics & bioinformatics.

Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions.

Ileana M. Cristea, I. Cristea, Y. Miteva, 2013, Analytical chemistry.

A Targeted Spatial-Temporal Proteomics Approach Implicates Multiple Cellular Trafficking Pathways in Human Cytomegalovirus Virion Maturation*

I. Cristea, T. Shenk, Nathaniel J. Moorman, 2009, Molecular & Cellular Proteomics.

Enzyme clustering accelerates processing of intermediates through metabolic channeling

Ned S Wingreen, Maxwell Z. Wilson, Zemer Gitai, 2014, Nature Biotechnology.

Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis

I. Cristea, G. Valesini, C. Alessandri, 2004, Cell Death and Differentiation.

Proteomic Characterization of Pseudorabies Virus Extracellular Virions

L. Enquist, I. Cristea, T. Kramer, 2011, Journal of Virology.

Membrane lipids and cell death: an overview.

Ileana M Cristea, I. Cristea, M. Degli Esposti, 2004, Chemistry and physics of lipids.

The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli

I. Cristea, T. Silhavy, M. Semmelhack, 2011, Molecular microbiology.

The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses

A. Pichlmair, G. Kochs, I. Cristea, 2022, bioRxiv.

Host Innate Immune Response and Viral Immune Evasion During Alphaherpesvirus Infection.

I. Cristea, K. Lum, 2021, Current issues in molecular biology.

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation*

I. Cristea, Marni S. Crow, 2017, Molecular & Cellular Proteomics.

RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters

I. Cristea, E. Hartenian, Joel D. Federspiel, 2020, PLoS pathogens.

Fluorescent Proteins as Proteomic Probes*S

Ileana M Cristea, Brian T Chait, B. Chait, 2005, Molecular & Cellular Proteomics.

The life cycle and pathogenesis of human cytomegalovirus infection: lessons from proteomics

I. Cristea, Pierre M. Jean Beltran, 2014, Expert review of proteomics.

CHD4 is recruited by GATA4 and NKX2-5 silencers to repress non-cardiac gene programs in the developing heart

F. Conlon, W. Pu, I. Cristea, 2021, bioRxiv.

Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16

I. Cristea, Benjamin A. Diner, Tuo Li, 2012, Proceedings of the National Academy of Sciences.

Proteomic profiling of cardiac tissue by isolation of nuclei tagged in specific cell types (INTACT)

F. Conlon, J. Wallingford, I. Cristea, 2014, Development.

Functional Proteomics Establishes the Interaction of SIRT7 with Chromatin Remodeling Complexes and Expands Its Role in Regulation of RNA Polymerase I Transcription*

I. Cristea, T. Greco, Y. Miteva, 2011, Molecular & Cellular Proteomics.

Functional Proteomics Establishes the Interaction of SIRT7 with Chromatin Remodeling Complexes and Expands Its Role in Regulation of RNA Polymerase I Transcription*

I. Cristea, T. Greco, Y. Miteva, 2011, Molecular & Cellular Proteomics.

Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription

I. Cristea, E. Hartenian, Joel D. Federspiel, 2018, bioRxiv.

Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation.

A. Arnold, F. Conlon, I. Cristea, 2021, Developmental cell.

Cardiac Sex Differences are Established Prior to Gonad Formation

A. Arnold, F. Conlon, I. Cristea, 2020, bioRxiv.

Transcriptional Elongation of HSV Immediate Early Genes by the Super Elongation Complex Drives Lytic Infection and Reactivation from Latency.

Jesse H. Arbuckle, I. Cristea, Pierre M. Jean Beltran, 2017, Cell host & microbe.

HIV–host interactome revealed directly from infected cells

David Fenyö, Ileana M. Cristea, Michael P. Rout, 2016, Nature Microbiology.

The functional interactome landscape of the human histone deacetylase family

Amanda J. Guise, A. Nesvizhskii, Yang Luo, 2013, Molecular systems biology.

TRANSPIRE: A computational pipeline to elucidate intracellular protein movements from spatial proteomics datasets.

I. Cristea, M. A. Kennedy, William A Hofstadter, 2020, Journal of the American Society for Mass Spectrometry.

Location is everything: protein translocations as a viral infection strategy

I. Cristea, Katelyn C Cook, Katelyn C. Cook, 2018, Current Opinion in Chemical Biology.

Pellino‐2 in nonimmune cells: novel interaction partners and intracellular localization

I. Cristea, O. Bruland, E. Rødahl, 2021, FEBS letters.

TGF-β-induced DACT1 Biomolecular Condensates Repress Wnt Signaling To Promote Bone Metastasis

C. Brangwynne, Yibin Kang, I. Cristea, 2021, Nature Cell Biology.

Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex.

B. Chait, M. Rout, I. Cristea, 2008, Cell host & microbe.

Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project.

R. Aebersold, C. Lindskog, R. Moritz, 2021, Journal of proteome research.

Proteomic Studies of a Single CNS Synapse Type: The Parallel Fiber/Purkinje Cell Synapse

B. Chait, N. Heintz, I. Cristea, 2009, PLoS biology.

Diverse mechanisms evolved by DNA viruses to inhibit early host defenses

I. Cristea, X. Sheng, K. Lum, 2016, Critical reviews in biochemistry and molecular biology.

Identification of Staphylococcal Nuclease Domain-containing 1 (SND1) as a Metadherin-interacting Protein with Metastasis-promoting Functions*

Yibin Kang, I. Cristea, Zhen Xu, 2011, The Journal of Biological Chemistry.

The Impact of Mass Spectrometry-Based Proteomics on Fundamental Discoveries in Virology.

I. Cristea, T. Greco, Benjamin A. Diner, 2014, Annual review of virology.

Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivity.

I. Cristea, T. Shenk, T. Greco, 2012, Cell host & microbe.

Systematic Discovery of Structural Elements Governing Mammalian mRNA Stability

Reza Salavati, Saeed Tavazoie, Ileana M. Cristea, 2012, Nature.

Aurora B-dependent Regulation of Class IIa Histone Deacetylases by Mitotic Nuclear Localization Signal Phosphorylation*

Amanda J. Guise, I. Cristea, T. Greco, 2012, Molecular & Cellular Proteomics.

Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus Replication

B. Chait, C. Rice, M. Rout, 2010, Journal of Virology.

Lamin post-translational modifications: emerging toggles of nuclear organization and function.

I. Cristea, Laura A Murray-Nerger, 2021, Trends in biochemical sciences.

Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair

Joshua L. Justice, I. Cristea, Josiah E. Hutton, 2021, Nucleic acids research.

Sirtuin 7 Plays a Role in Ribosome Biogenesis and Protein Synthesis*

Ileana M Cristea, I. Cristea, T. Greco, 2013, Molecular & Cellular Proteomics.

Proteomics Tracing the Footsteps of Infectious Disease*

I. Cristea, T. Greco, 2017, Molecular & Cellular Proteomics.

A Proteomic Perspective of Inbuilt Viral Protein Regulation: pUL46 Tegument Protein is Targeted for Degradation by ICP0 during Herpes Simplex Virus Type 1 Infection*

I. Cristea, T. Greco, B. Sodeik, 2013, Molecular & Cellular Proteomics.

Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection

Jared E. Toettcher, J. Toettcher, I. Cristea, 2016, mBio.

Approaches for Studying the Subcellular Localization, Interactions, and Regulation of Histone Deacetylase 5 (HDAC5).

Amanda J. Guise, I. Cristea, Amanda J Guise, 2016, Methods in molecular biology.

Nuclear Import of Histone Deacetylase 5 by Requisite Nuclear Localization Signal Phosphorylation*

Amanda J. Guise, I. Cristea, T. Greco, 2010, Molecular & Cellular Proteomics.

Running title: HDAC5 regulation via NLS phosphorylation

Amanda J. Guise, I. Cristea, T. Greco, 2010 .

Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length

Amanda J. Guise, I. Cristea, V. Zakian, 2015, Nature Communications.

A high-stringency blueprint of the human proteome

Rebekah L. Gundry, Joshua L. Justice, R. Aebersold, 2020, Nature Communications.

Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP 2I Transcription Factor Graphical Abstract Highlights

M. Llinás, Tracey L. Campbell, I. Cristea, 2022 .

Induction of Autophagy in Axonal Dystrophy and Degeneration

Ileana M. Cristea, Qing Jun Wang, Michael P. Rout, 2006, The Journal of Neuroscience.

Identification of RNA Binding Proteins Associated with Dengue Virus RNA in Infected Cells Reveals Temporally Distinct Host Factor Requirements

I. Cristea, S. Thompson, T. Greco, 2016, PLoS neglected tropical diseases.

Determining the Composition and Stability of Protein Complexes Using an Integrated Label-Free and Stable Isotope Labeling Strategy.

Amanda J. Guise, I. Cristea, T. Greco, 2016, Methods in molecular biology.

Discovery of host-viral protein complexes during infection.

I. Cristea, S. Terhune, Daniel Rowles, 2013, Methods in molecular biology.

Resolving the composition of protein complexes using a MALDI LTQ orbitrap

Yang Luo, I. Cristea, T. Kramer, 2010, Journal of the American Society for Mass Spectrometry.

A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection.

I. Cristea, Pierre M. Jean Beltran, Rommel A Mathias, 2016, Cell systems.

The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation.

F. Conlon, I. Cristea, X. Yang, 2016, Developmental cell.

Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion.

I. Cristea, Tuo Li, Jin Chen, 2013, Cell host & microbe.

Bone Vascular Niche E-selectin Induces Mesenchymal-Epithelial Transition and Wnt Activation in Cancer Cells to Promote Bone Metastasis

Yibin Kang, I. Cristea, T. Greco, 2019, Nature Cell Biology.

Post-translational Modifications Regulate Class IIa Histone Deacetylase (HDAC) Function in Health and Disease*

Amanda J. Guise, I. Cristea, Rommel A Mathias, 2015, Molecular & Cellular Proteomics.

Histone Deacetylases in Herpesvirus Replication and Virus-Stimulated Host Defense

Amanda J. Guise, I. Cristea, Hanna G. Budayeva, 2013, Viruses.

Kinesin-3 mediates axonal sorting and directional transport of alphaherpesvirus particles in neurons.

L. Enquist, Matthew P. Taylor, I. Cristea, 2012, Cell host & microbe.

Post-translational modification control of viral DNA sensors and innate immune signaling.

I. Cristea, T. Greco, Dawei Liu, 2021, Advances in virus research.

Mechanical Force Induces Phosphorylation-Mediated Signaling that Underlies Tissue Response and Robustness in Xenopus Embryos.

N. Ueno, I. Cristea, Pierre M. Jean Beltran, 2019, Cell systems.

Contribution of Mass Spectrometry-Based Proteomics to Discoveries in Developmental Biology.

I. Cristea, T. Greco, Yutaka Hashimoto, 2019, Advances in experimental medicine and biology.

Virus-host protein interactions as footprints of human cytomegalovirus replication.

I. Cristea, Cora N. Betsinger, Matthew D. Tyl, 2021, Current opinion in virology.

Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection

I. Cristea, X. Sheng, Yutaka Hashimoto, 2020, Nature Communications.

Sirtuins Are Evolutionarily Conserved Viral Restriction Factors

Ileana M. Cristea, Thomas Shenk, I. Cristea, 2014, mBio.

A complex of YlbF, YmcA and YaaT regulates sporulation, competence and biofilm formation by accelerating the phosphorylation of Spo0A

Ileana M Cristea, D. Dubnau, I. Cristea, 2013, Molecular microbiology.

Considerations for Identifying Endogenous Protein Complexes from Tissue via Immunoaffinity Purification and Quantitative Mass Spectrometry.

I. Cristea, Joel D. Federspiel, 2019, Methods in molecular biology.

The nuclear basket proteins Mlp 1 p and Mlp 2 p are part of a dynamic interactome including Esc 1 p and the proteaosme

B. Chait, M. Niepel, M. Rout, 2013 .

YfmK is an Nε-lysine acetyltransferase that directly acetylates the histone-like protein HBsu in Bacillus subtilis

D. Dubnau, I. Cristea, T. Greco, 2019, Proceedings of the National Academy of Sciences.

Regulation, Function, and Detection of Protein Acetylation in Bacteria

I. Cristea, Valerie J. Carabetta, 2017, Journal of bacteriology.

Temporal Regulation of the Bacillus subtilis Acetylome and Evidence for a Role of MreB Acetylation in Cell Wall Growth

D. Dubnau, I. Cristea, T. Greco, 2016, mSystems.

Running title: SIRT7 regulates Pol III transcription

I. Cristea, T. Greco, Y. Tsai, 2013 .

Methods for characterizing protein acetylation during viral infection.

I. Cristea, Ashton N. Combs, L. A. Murray, 2019, Methods in enzymology.

Orchestration of protein acetylation as a toggle for cellular defense and virus replication

I. Cristea, X. Sheng, L. A. Murray, 2018, Nature Communications.

The DNA Sensor IFIX Drives Proteome Alterations To Mobilize Nuclear and Cytoplasmic Antiviral Responses, with Its Acetylation Acting as a Localization Toggle

I. Cristea, K. Lum, T. Greco, 2021, mSystems.

Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.

E. Wanker, J. Botas, I. Cristea, 2022, Cell systems.

Proteomics techniques and their application to hematology.

Ileana M Cristea, Anthony D Whetton, I. Cristea, 2004, Blood.

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression*

Ileana M Cristea, I. Cristea, K. Lum, 2015, Molecular & Cellular Proteomics.

Thiouracil Cross-Linking Mass Spectrometry: a Cell-Based Method To Identify Host Factors Involved in Viral Amplification

I. Cristea, S. Thompson, T. Greco, 2013, Journal of Virology.

The Number of Alphaherpesvirus Particles Infecting Axons and the Axonal Protein Repertoire Determines the Outcome of Neuronal Infection

L. Enquist, I. Cristea, T. Greco, 2015, mBio.

Proteomic Technologies for Deciphering Local and Global Protein Interactions.

I. Cristea, T. Greco, M. A. Kennedy, 2020, Trends in biochemical sciences.

Cell-cycle-dependent phosphorylation of the nuclear pore Nup107–160 subcomplex

G. Blobel, B. Chait, I. Cristea, 2007, Proceedings of the National Academy of Sciences.

The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection

I. Cristea, X. Sheng, Xinlei Sheng, 2021, PLoS pathogens.

Global Analysis of Cdc14 Phosphatase Reveals Diverse Roles in Mitotic Processes*

Ileana M Cristea, Brian T Chait, F. Cross, 2010, The Journal of Biological Chemistry.

Glycoproteins gE and gI Are Required for Efficient KIF1A-Dependent Anterograde Axonal Transport of Alphaherpesvirus Particles in Neurons

L. Enquist, Matthew P. Taylor, I. Cristea, 2013, Journal of Virology.

Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 (SIRT4) Functions.

I. Cristea, Cora N. Betsinger, 2019, Journal of proteome research.

The Response Regulator SprE (RssB) Is Required for Maintaining Poly(A) Polymerase I-Degradosome Association during Stationary Phase

I. Cristea, T. Silhavy, Valerie J. Carabetta, 2010, Journal of bacteriology.

Sirtuin Lipoamidase Activity Is Conserved in Bacteria as a Regulator of Metabolic Enzyme Complexes

Ileana M. Cristea, I. Cristea, T. Silhavy, 2017, mBio.

Complementary proteomic analysis of protein complexes.

Ileana M Cristea, F. Conlon, I. Cristea, 2012, Methods in molecular biology.

Proapoptotic Bid binds to monolysocardiolipin, a new molecular connection between mitochondrial membranes and cell death

I. Cristea, S. Gaskell, C. Dive, 2003, Cell Death and Differentiation.

The DNA Sensor cGAS is Decorated by Acetylation and Phosphorylation Modifications in the Context of Immune Signaling

I. Cristea, K. Lum, T. Greco, 2020, Molecular & Cellular Proteomics.

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

I. Cristea, Joel D. Federspiel, K. Lum, 2018, Cell systems.

The Host-Pathogen Ecosystem Viewed Through the Prism of Proteomics*

I. Cristea, 2017, Molecular & Cellular Proteomics.

Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis

Laura E. Herring, F. Conlon, I. Cristea, 2017, PLoS genetics.

Workflows and considerations for investigating protein interactions of viral DNA sensors.

I. Cristea, Bokai Song, Timothy R. Howard, 2019, Methods in enzymology.

Exploring and Exploiting Proteome Organization during Viral Infection

I. Cristea, Pierre M. Jean Beltran, Katelyn C Cook, 2017, Journal of Virology.

Human Cytomegalovirus UL29/28 Protein Interacts with Components of the NuRD Complex Which Promote Accumulation of Immediate-Early RNA

B. Chait, M. Rout, I. Cristea, 2010, PLoS pathogens.

herpes simplex virus-1 immunosuppression

I. Cristea, K. Lum, Aaron Javitt, 2015 .

Particles in Neurons Axonal Transport of Alphaherpesvirus Efficient KIF1A-Dependent Anterograde Glycoproteins gE and gI Are Required for

P. Taylor, I. Cristea, T. Greco, 2014 .

Palladium-catalysed [ p2a+ p2s] cycloadditions of a-bromoalkyl ketenes to cyclopentadiene

J. M. Dickinson, I. Cristea, I. Fairlamb, 2000 .

Palladium-Catalyzed [π2a+π2s] Cycloadditions of α-Bromoalkyl Ketenes to Cyclopentadiene.

J. M. Dickinson, I. Cristea, I. Fairlamb, 2000 .

Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity

Amanda J. Guise, I. Cristea, J. Capra, 2016, PLoS genetics.

A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.

F. Conlon, I. Cristea, T. Greco, 2013, Journal of proteome research.

Tcf21 regulates the specification and maturation of proepicardial cells

F. Conlon, I. Cristea, Y. Miteva, 2013, Development.

HVint: A Strategy for Identifying Novel Protein-Protein Interactions in Herpes Simplex Virus Type 1*

A. Shepherd, M. Topf, P. Ashford, 2016, Molecular & Cellular Proteomics.

ComGA‐RelA interaction and persistence in the Bacillus subtilis K‐state

D. Dubnau, I. Cristea, J. Hahn, 2015, Molecular microbiology.

Integrating Lys-N proteolysis and N-terminal guanidination for improved fragmentation and relative quantification of singly-charged ions

I. Cristea, T. Greco, Anisha Shakya, 2010, Journal of the American Society for Mass Spectrometry.

Complex formation and processing of the minor transformation pilins of Bacillus subtilis

D. Dubnau, I. Cristea, J. Mann, 2013, Molecular microbiology.

Two Modes of the Axonal Interferon Response Limit Alphaherpesvirus Neuroinvasion

L. Enquist, I. Cristea, T. Greco, 2016, mBio.

The Nuclear DNA Sensor IFI16 Indiscriminately Binds to and Diminishes Accessibility of the HSV-1 Genome to Suppress Infection

I. Cristea, K. Lum, M. A. Kennedy, 2022, mSystems.

Statistical Inference of Peroxisome Dynamics

Olga Vitek, Cyril Galitzine, Ileana M. Cristea, 2018, RECOMB.

Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development.

F. Conlon, I. Cristea, T. Greco, 2023, Developmental cell.

Quantitative Proteomic Profiling of Murine Embryonic Heart Development Reveals a Role for the Mevalonate Pathway in Cardiomyocyte Proliferation

Laura E. Herring, F. Conlon, I. Cristea, 2022, bioRxiv.

Probing phosphorylation‐dependent protein interactions within functional domains of histone deacetylase 5 (HDAC5)

Amanda J. Guise, I. Cristea, Rommel A Mathias, 2014, Proteomics.

Guanidination chemistry for qualitative and quantitative proteomics.

S. Mohammed, I. Cristea, S. Gaskell, 2006, Rapid communications in mass spectrometry : RCM.

Orchestration of Mitochondrial Function and Remodeling by Post-Translational Modifications Provide Insight into Mechanisms of Viral Infection

I. Cristea, Ji Woo Park, Matthew D. Tyl, 2023, Biomolecules.

A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates With the Vacuole in Saccharomyces cerevisiae*

Avner Schlessinger, Jean Salamero, Ursula Pieper, 2011, Molecular & Cellular Proteomics.

Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR/Erk2 Signaling Pathway during Embryogenesis.

N. Ueno, I. Cristea, N. Kinoshita, 2020, Cell reports.

purification–mass spectrometry data

Amber L. Couzens, Mihaela E. Sardiu, Wade H. Dunham, 2022 .

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

I. Cristea, Joel D. Federspiel, K. Lum, 2019, Molecular & Cellular Proteomics.

Blowing Off Steam: Virus Inhibition of cGAS DNA Sensing.

I. Cristea, Benjamin A. Diner, 2015, Cell host & microbe.

IFI16 phase separation via multi-phosphorylation drives innate immune signaling

I. Cristea, K. Lum, Dawei Liu, 2023, Nucleic acids research.

Conjugation of magnetic beads for immunopurification of protein complexes.

B. Chait, I. Cristea, 2011, Cold Spring Harbor protocols.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics*

Ileana M. Cristea, I. Cristea, Joel D. Federspiel, 2019, Molecular & Cellular Proteomics.

The Biochemical Evolution of Protein Complexes.

I. Cristea, T. Greco, 2016, Trends in biochemical sciences.

The viral packaging motor potentiates Kaposi’s sarcoma-associated herpesvirus gene expression late in infection

I. Cristea, B. Glaunsinger, Dawei Liu, 2023, PLoS pathogens.

Bone Vascular Niche E-selectin Induces Mesenchymal-Epithelial Transition and Wnt Activation in Cancer Cells to Promote Bone Metastasis

Yibin Kang, I. Cristea, T. Greco, 2019, Nature Cell Biology.

Molecular Systems Biology Peer Review Process File the Functional Interactome of Pyhin Immune Regulators Reveals Ifix Is a Sensor of Viral Dna Transaction Report

I. Cristea, T. Greco, Jennifer Wang, 2022 .

Orchestration of protein acetylation as a toggle for cellular defense and virus replication

I. Cristea, L. A. Murray, Xinlei Sheng, 2018, Nature Communications.

YlaN is an iron(II) binding protein that functions to relieve Fur-mediated repression of gene expression in Staphylococcus aureus

Timothy G. Stephens, Eric P. Skaar, I. Cristea, 2023, bioRxiv.

Proteomic profiling of cardiac tissue by isolation of nuclei tagged in specific cell types (INTACT)

F. Conlon, J. Wallingford, I. Cristea, 2014, Development.

The Emerging Role of Nuclear Viral DNA Sensors*

I. Cristea, K. Lum, Benjamin A. Diner, 2015, The Journal of Biological Chemistry.

Intercellular communication within the virus microenvironment affects the susceptibility of cells to secondary viral infections

Joshua L. Justice, I. Cristea, K. Lum, 2023, Science advances.

Resolving the composition of protein complexes using a MALDI LTQ orbitrap

Yang Luo, I. Cristea, T. Kramer, 2010, Journal of the American Society for Mass Spectrometry.

Exploring alternative proteases and fragmentation methods for proteomics

Kiyoko F. Aoki-Kinoshita, Monika S. Doblin, Kristina L. Ford, 2022 .

Initiating Events in Direct Cardiomyocyte Reprogramming.

F. Conlon, I. Cristea, T. Greco, 2018, Cell reports.

Differential Contributions of Interferon Classes to Host Inflammatory Responses and Restricting Virus Progeny Production.

I. Cristea, K. Lum, Tavis J Reed, 2024, Journal of Proteome Research.

Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts.

I. Cristea, Matthew D. Tyl, A. Tadych, 2024, Nature methods.

Liquid-liquid phase separation in innate immunity.

I. Cristea, Jinhang Yang, Dawei Liu, 2024, Trends in immunology.

Sirtuin 2 promotes human cytomegalovirus replication by regulating cell cycle progression

Joshua L. Justice, I. Cristea, Hanna G. Budayeva, 2023, mSystems.

ARPE-19 Epithelial Cells Fail To Initiate Type-I Interferon Signaling in Response to Human Cytomegalovirus Infection

I. Cristea, T. Greco, Mariana Andrade-Medina, 2024, bioRxiv.

Infection-induced peripheral mitochondria fission drives ER encapsulations and inter-mitochondria contacts that rescue bioenergetics

I. Cristea, V. Pražák, E. Quemin, 2024, Nature communications.

The 2023 Report on the Proteome from the HUPO Human Proteome Project.

C. Lindskog, I. Cristea, N. Bandeira, 2024, Journal of proteome research.

Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signatures

Joshua L. Justice, I. Cristea, T. Greco, 2024, bioRxiv.

Mapping protein-protein interactions by mass spectrometry.

M. Varjosalo, I. Cristea, Xiaonan Liu, 2024, Mass spectrometry reviews.

Virology meets Proteomics

I. Cristea, David R. Graham, 2015, Proteomics.