C. Mecucci

C. Mecucci, M. Martelli, L. Ruggeri, 2017, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

A novel germline variant in PIK3R1 results in SHORT syndrome associated with TAL/LMO T‐cell acute lymphoblastic leukemia

S. Bortoluzzi, A. Coppe, C. Mecucci, 2020, American journal of hematology.

The short arm of chromosome 6 is nonrandomly rearranged in secondary myelodysplastic syndromes.

C. Mecucci, H. van den Berghe, M. Boogaerts, 1988, Cancer genetics and cytogenetics.

Paracentric inversions on the long arm of chromosome 5 in secondary myelodysplastic disorders.

C. Mecucci, H. van den Berghe, C. Doyen, 1987, Cancer genetics and cytogenetics.

Acute Myeloblastic Leukemia after Adjuvant Chemotherapy with Melphalan in Breast Cancer. Case Report with Cytogenetic Analysis

L. Crinò, M. Tonato, C. Mecucci, 1983, Tumori.

The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing

C. Mecucci, Viktoryia Sidarovich, G. Basso, 2020, Journal of Hematology & Oncology.

NPM1 mutations may reveal acute myeloid leukemia in cases otherwise morphologically diagnosed as myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms

B. Falini, C. Mecucci, G. Martinelli, 2015, Leukemia & lymphoma.

Chronic myelogenous leukemia after treatment with 131I for thyroid carcinoma. Report of a case and review of the literature.

C. Mecucci, M. Stul, G. Verhoef, 1991, Cancer genetics and cytogenetics.

Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

K. Stegmaier, G. Alexe, C. Mecucci, 2022, Cell Death & Disease.

The detection of E2A rearrangement or E2A‐PBXI fusion transcript in t(1;19) leukemia to the editors

C. Mecucci, C. de Wolf‐Peeters, M. Stul, 1995, Genes, chromosomes & cancer.

14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T and myeloid immature acute leukemia.

S. Aerts, C. Mecucci, Zeynep Kalender Atak, 2021, Blood.

Myeloid cell diff erentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation Most chromosomal translocations in myelodysplastic syndromes (MDS)

P. Brousset, P. Marynen, A. Hagemeijer, 2008 .

Burkitt-type ALL with variant t(2;8) and complex additional rearrangements at diagnosis.

G. Tricot, A. Aventín, C. Mecucci, 1987, Annales de Genetique.

Chromothripsis is a frequent event and underlies typical genetic changes in early T-cell precursor lymphoblastic leukemia in adults

C. Mecucci, P. Gorello, C. Matteucci, 2022, Leukemia.

Modern treatment approaches to adult acute T-lymphoblastic and myeloid/T-lymphoblastic leukemia: from current standards to precision medicine

C. Mecucci, R. la Starza, R. Bassan, 2022, Current opinion in oncology.

New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia.

C. Mecucci, P. Gorello, M. Giordan, 2013, Blood.

Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts

C. Mecucci, J. Maciejewski, U. Germing, 2013, Leukemia.

Myelodysplastic syndromes: recent advances.

M Cazzola, M. Cazzola, C. Mecucci, 2001, Haematologica.

Translocation (Y;1)(q12;q12) in hematologic malignancies. Report on two new cases, FISH characterization, and review of the literature.

C. Mecucci, L. Michaux, G. Verhoef, 1996, Cancer genetics and cytogenetics.

An identical translocation between chromosome 1 and 15 in two patients with myelodysplastic syndromes

G. Tricot, C. Mecucci, H. Berghe, 1986, British journal of haematology.

Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors

C. Mecucci, T. Schulz, D. Wolf, 2003, Nature Medicine.

MLL tandem duplication in two cases of acute myelocytic leukemia with unbalanced translocations: der(16)t(11;16)(q23;p13) and der(18)t(11;18)(q22;p11.2).

S. Casas, A. Aventín, J. Sierra, 2003, Cancer genetics and cytogenetics.

Interstitial insertion of AF10 into the ALL1 gene in a case of infant acute lymphoblastic leukemia.

C. Mecucci, G. Cimino, C. Matteucci, 1998, Cancer genetics and cytogenetics.

Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin

S. Ascani, C. Mecucci, P. Covarelli, 2018, Molecular Cytogenetics.

Detection of amplified sequences at 5q11-->q13 in a homogenously staining region found by fluorescent in situ hybridization in a case of B-cell non-Hodgkin's lymphoma.

C. Mecucci, C. de Wolf‐Peeters, J. Cassiman, 1994, Cytogenetics and cell genetics.

"Jumping" translocation of 9q in a case of follicular lymphoma.

C. Mecucci, C. de Wolf‐Peeters, H. Weier, 1994, Cancer genetics and cytogenetics.

FISH identifies different types of duplications with 12q13-15 as the commonly involved segment in B-cell lymphoproliferative malignancies characterized by partial trisomy 12.

J. Vermeesch, A. Hagemeijer, A. Delannoy, 1997, Genes, chromosomes & cancer.

A simple prognostic scoring system for newly diagnosed cytogenetically normal acute myeloid leukemia: retrospective analysis of 530 patients

R. Foà, M. Gobbi, P. Mazza, 2011, Leukemia & lymphoma.

Significant reduction of the hybrid BCR/ABL transcripts after induction and consolidation therapy is a powerful predictor of treatment response in adult Philadelphia-positive acute lymphoblastic leukemia

G. Specchia, R. Foà, A. Vitale, 2005, Leukemia.

Cytogenetic analysis of B cell chronic lymphoid leukemias classified according to morphologic and immunophenotypic (FAB) criteria.

C. Mecucci, G. Verhoef, J. Hernández, 1995, Leukemia.

Chromosome 11q rearrangements in B non Hodgkin's lymphoma

C. Mecucci, M. Stul, G. Verhoef, 1992, British journal of haematology.

Lenalidomide treatment of myelodysplastic syndromes with chromosome 5q deletion: Results from the National Registry of the Italian Drug Agency

C. Mecucci, S. Tura, A. Covezzoli, 2018, European journal of haematology.

MN1-ETV6 fusion gene arising from MDS with 5q-.

Valeria Nofrini, C. Mecucci, P. Gorello, 2011, Leukemia research.

Deletions of the long arm of chromosome 7 in myeloid disorders: loss of band 7q32 implies worst prognosis

C. Mecucci, J. Dierlamm, Jesús M. Hernández, 1996, British journal of haematology.

Association of Unbalanced Translocation der(1;7) with Germline GATA2 Mutations.

J. Tchinda, S. Holland, C. Mecucci, 2021, Blood.

Leukemic recombinations involving heterochromatin in myeloproliferative disorders with t(1;9).

C. Mecucci, D. Koumbi, P. Vandenberghe, 2005, Cancer genetics and cytogenetics.

Dicentric (1;15) in myeloid disorders.

C. Mecucci, J. Dierlamm, L. Michaux, 1996, Cancer genetics and cytogenetics.

Review of guidelines for the identification and clinical care of patients with genetic predisposition for hematological malignancies

C. Mecucci, M. Wlodarski, B. Schlegelberger, 2021, Familial Cancer.

Polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes: not always a POEMS syndrome.

M. Mancini, C. Mecucci, A. Cuneo, 2006, Haematologica.

H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor beta gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22).

J. Kutok, C. Mecucci, D. Gilliland, 2001, Blood.

FISH analysis reveals frequent co-occurrence of 4q24/TET2 and 5q and/or 7q deletions.

Valeria Nofrini, C. Mecucci, S. Paolini, 2012, Leukemia research.

Update on the prognostic implication of morphology, histology, and karyotype in primary myelodysplastic syndromes.

C. Mecucci, C. de Wolf‐Peeters, H. van den Berghe, 1991, Hematologic pathology.

Short communication Typical CBF b /MYH11 fusion due to insertion of the 3 9 - MYH11 gene into 16q22 in acute monocytic leukemia with normal chromosomes 16 and trisomies 8 and 22

A. Aventín, J. Sierra, C. Mecucci, 2000 .

New dead/H-box helicase gene (ddx41) mutation in an Italian family with recurrent leukemia

R. Latagliata, C. Mecucci, C. Matteucci, 2021, Leukemia & lymphoma.

T‐cell lymphoma developing in Hodgkin's disease: Evidence for two clones

J. Delabie, C. Mecucci, C. de Wolf‐Peeters, 1993, The Journal of pathology.

Totipotent stem cells bearing del(20q) maintain multipotential differentiation in Shwachman Diamond syndrome

Valeria Nofrini, C. Mecucci, M. Martelli, 2009, British journal of haematology.

Cytogenetic characterization of acute myeloid leukemia in Shwachman's syndrome. A case report.

C. Mecucci, M. Martelli, C. Matteucci, 2000, Haematologica.

Comparative genomic hybridization identifies 17q11.2 approximately q12 duplication as an early event in cutaneous T-cell lymphomas.

C. Mecucci, M. Martelli, G. Girolomoni, 2008, Cancer genetics and cytogenetics.

Clonal chromosome rearrangements in hairy cell leukemia: personal experience and review of literature.

C. Mecucci, D. Trafalis, G. Pantelias, 2001, Cancer genetics and cytogenetics.

Characterization of deletions of chromosome 7 short arm occurring as primary karyotypic anomaly in acute myeloid leukaemia

C. Mecucci, H. van den Berghe, M. Boogaerts, 1989, British journal of haematology.

Characterization by chromosome painting of balanced and unbalanced X chromosome translocations in myelodysplastic syndromes.

C. Mecucci, L. Michaux, H. van den Berghe, 1995, Cancer genetics and cytogenetics.

11q-chromosome is associated with abnormal iron stores in myelodysplastic syndromes.

G. Tricot, A. Delannoy, C. Mecucci, 1987, Cancer genetics and cytogenetics.

High incidence of chromosome abnormalities in IgG3 myeloma.

C. Mecucci, H. van den Berghe, A. Louwagie, 1984, Cancer genetics and cytogenetics.

Cytogenetic and molecular studies of the Philadelphia translocation in myelodysplastic syndromes. Report of two cases and review of the literature.

C. Mecucci, M. Stul, J. Cassiman, 1992, Cancer genetics and cytogenetics.

Megakaryoblastic leukemia with an N-ras mutation and late acquisition of a Philadelphia chromosome.

C. Mecucci, M. Stul, P. Martiat, 1991, Leukemia.

MYB deregulation from a EWSR1-MYB fusion at leukemic evolution of a JAK2V617F positive primary myelofibrosis

C. Mecucci, P. Gorello, G. Barba, 2016, Molecular Cytogenetics.

Cytogenetic characterization of three cases of unusual B-cell non-Hodgkin's lymphoma.

J. Delabie, C. Mecucci, C. de Wolf‐Peeters, 1991, Cancer genetics and cytogenetics.

Molecular Cytogenetics Detect an Unbalanced t(2;13)(q36;q14) and PAX3–FOXO1 Fusion in Rhabdomyosarcoma With Mixed Embryonal/Alveolar Features

Valeria Nofrini, C. Mecucci, R. la Starza, 2015, Pediatric blood & cancer.

Sensitivity of cutaneous chronic myelomonocytic leukaemia lesions to hypomethylating treatment

C. Mecucci, C. Matteucci, P. Di Bartolomeo, 2017, European Journal of Dermatology.

Chromosome 1p abnormalities in B non Hodgkin's lymphoma.

P. Cin, C. Mecucci, C. Wolf‐peeters, 1991, Leukemia & lymphoma.

Highly aggressive T-cell acute lymphoblastic leukemia with t(8;14)(q24;q11): extensive genetic characterization and achievement of early molecular remission and long-term survival in an adult patient

C. Mecucci, C. Matteucci, A. Rambaldi, 2014, Blood Cancer Journal.

Rearrangements of the short arm of chromosome No. 6 in T-cell lymphomas.

G. Tricot, C. Mecucci, H. van den Berghe, 1985, Leukemia research.

Some karyotypic aspects of human leukemia.

C. Mecucci, H. van den Berghe, 1987, Haematology and blood transfusion.

Multiple EWSR1-WT1 and WT1-EWSR1 copies in two cases of desmoplastic round cell tumor.

P. D. Dal Cin, Valeria Nofrini, C. Mecucci, 2013, Cancer genetics.

Born to be exported: COOH-terminal nuclear export signals of different strength ensure cytoplasmic accumulation of nucleophosmin leukemic mutants.

Brunangelo Falini, Maria Paola Martelli, Niccolò Bolli, 2007, Cancer research.

Nanopore sequencing for the screening of myeloid and lymphoid neoplasms with eosinophilia and rearrangement of PDGFRα, PDGFRβ, FGFR1 or PCM1-JAK2

C. Mecucci, P. Guglielmelli, F. Mannelli, 2021, Biomarker research.

Hypereosinophilic SyndromeResearch Paper

P. Marynen, A. Aventín, C. Mecucci, 2005 .

Rapid Reversion of Loeffler's Endocarditis by Imatinib in Early Stage Clonal Hypereosinophilic Syndrome

C. Mecucci, M. Galderisi, A. D’Errico, 2004, Leukemia & lymphoma.

Successful use of the same slide for consecutive fluorescence in situ hybridization experiments

C. Mecucci, J. Dierlamm, L. Michaux, 1996, Genes, chromosomes & cancer.

Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin

N. Bolli, B. Falini, C. Mecucci, 2005, Leukemia.

NPM1 Mutational Status Underlines Different Biological Features in Pediatric AML

C. Mecucci, F. Locatelli, A. Marchetti, 2021, Cancers.

Aberrant subcellular expression of nucleophosmin and NPM-MLF1 fusion protein in acute myeloid leukaemia carrying t(3;5): A comparison with NPMc+ AML

N. Bolli, B. Falini, C. Mecucci, 2006, Leukemia.

Chromothripsis is a frequent event and underlies typical genetic changes in early T-cell precursor lymphoblastic leukemia in adults

C. Mecucci, P. Gorello, C. Matteucci, 2022, Leukemia.

Shwachman syndrome as mutator phenotype responsible for myeloid dysplasia/neoplasia through karyotype instability and chromosomes 7 and 20 anomalies

C. Mecucci, G. Menna, C. Danesino, 2006, Genes, chromosomes & cancer.

MYB rearrangements and over‐expression in T‐cell acute lymphoblastic leukemia

S. Chiaretti, A. Vitale, C. Mecucci, 2021, Genes, chromosomes & cancer.

Exon-12 nucleophosmin (NPM) mutation and aberrant cytoplasmic expression of NPM protein in leukemia cell line OCI-AML3

N. Bolli, B. Falini, C. Mecucci, 2005 .

Simultaneous detection of NPM1 and FLT3-ITD mutations by capillary electrophoresis in acute myeloid leukemia

B. Falini, F. Lo‐Coco, C. Mecucci, 2005, Leukemia.

Interphase FISH for Y chromosome, VNTR polymorphisms, and RT-PCR for BCR-ABL in the monitoring of HLA-matched and mismatched transplants.

C. Mecucci, M. Martelli, F. Aversa, 2000, Cancer genetics and cytogenetics.

t(2;18) and t(18;22) variant chromosomal translocations and bcl-2 gene rearrangements in human malignant lymphomas.

C. Mecucci, C. Larsen, D. Leroux, 1990, Nouvelle revue francaise d'hematologie.

Involvement of a member of the histone cluster 1 at 6p21 in NUP98-positive MDS/AML

C. Mecucci, G. Rossi, R. la Starza, 2017, Leukemia & lymphoma.

NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group

F. Locatelli, D. D. Giacomo, C. Mecucci, 2017, Leukemia.

Inv(11)(p15q22)/NUP98-DDX10 fusion and isoforms in a new case of de novo acute myeloid leukemia.

Valeria Nofrini, C. Mecucci, P. Gorello, 2013, Cancer genetics.

Nucleophosmin Gene Mutations Are Predictors of Favourable Prognosis in Acute Myeloid Leukemia with a Normal Kayotype and Can Be Used as a New Marker for Quantitative PCR To Detect Minimal Residual Disease.

W. Hiddemann, T. Haferlach, B. Falini, 2005 .

The Italian External Quality Assessment Scheme in Classical Cytogenetics: Four Years of Activity

E. Calzolari, D. Taruscio, C. Mecucci, 2008, Public Health Genomics.

From cloning of a new fusion involving the nucleoporin 98 (NUP98) gene to a common NUP98-homedomain fusion gene genetic footpri

C. Mecucci, P. Gorello, J., 2008 .

Cytogenetic studies in T-cell malignancies.

C. Mecucci, H. van den Berghe, M. Boogaerts, 1988, Cancer genetics and cytogenetics.

Haploidentical age-adapted myeloablative transplant and regulatory and effector T cells for acute myeloid leukemia.

B. Falini, C. Mecucci, M. Martelli, 2021, Blood advances.

CMRL-T, a novel T-cell line showing asynchronous phenotype (CD34+/CD1a−/TCRαβ+) and dual T-cell receptor β chain

C. Mecucci, F. Salvatore, P. Mirabelli, 2006, Leukemia.

A novel dic(1;10) in a patient with myelodysplastic syndrome.

C. Mecucci, R. la Starza, K. Manola, 2002, Cancer genetics and cytogenetics.

Short communication A novel dic(1;10) in a patient with myelodysplastic syndrome

C. Mecucci, R. L. Starza, K. Manola, 2002 .

Philadelphia-positive acute lymphoblastic leukemia with multiple subclones including duplication of the Philadelphia chromosome and Abelson oncogene.

R. Foà, A. Vitale, C. Mecucci, 2002, Cancer genetics and cytogenetics.

Characterization of 12p molecular events outside ETV6 in complex karyotypes of acute myeloid malignancies

P. Marynen, F. Mandelli, C. Mecucci, 1999, British journal of haematology.

Identification of multiple copies of a 20q-chromosome in a case of myelodysplastic syndrome: a FISH study.

T. L. Hood, P. Marynen, J. Vermeesch, 1999, Leukemia research.

Unbalanced 6p translocation as primary karyotypic anomaly in secondary acute nonlymphocytic leukemia.

M. Mancini, C. Mecucci, G. Alimena, 1992, Cancer genetics and cytogenetics.

Reciprocal translocation involving 3q21 in an unusual myeloproliferative disorder with myelodysplastic features and prominent dysmegakaryopoiesis.

C. Mecucci, G. Alimena, V. Burgio, 1991, Cancer genetics and cytogenetics.

Translocation (14;19)(q32;q13.1) in a Young Patient who Developed a Large Cell Lymphoma after an Initial Diagnosis of CLL.

C. Mecucci, M. Stul, J. Cassiman, 1991, Leukemia & lymphoma.

The karyotype in secondary hematologic disorders after treatment for Hodgkin's disease. A study of 19 patients.

C. Mecucci, H. van den Berghe, M. Boogaerts, 1988, Cancer genetics and cytogenetics.

Translocation t(11;21)(q24;q11.2) is a new nonrandomly occurring chromosome change in myelodysplastic syndromes.

C. Mecucci, H. van den Berghe, M. Boogaerts, 1988, Cancer genetics and cytogenetics.

Morphologic, Immunologic, and Cytogenetic Classification of the Chronic (Mature) B and T Lymphoid Leukemias: Fourth Meeting of the MIC Cooperative Study Group

C. Mecucci, G. Juliusson, J. Bennett, 1990 .

Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): biologic and clinical features.

Brunangelo Falini, B. Falini, C. Mecucci, 2007, Blood.

with t(8;11)(p11.2;p15) gene in acute myeloid leukemia associated NSD3 is fused to the NUP98

A. Veronese, M. Negrini, C. Mecucci, 2011 .

Different boundaries characterize isolated and non-isolated 5q deletions in myelodysplastic syndromes and acute myeloid leukemias

Valeria Nofrini, C. Mecucci, G. Barba, 2012, Haematologica.

Myelodysplastic disorders carrying both isolated del(5q) and JAK2V617F mutation: concise review, with focus on lenalidomide therapy

M. Voso, C. Mecucci, V. Simeon, 2014, OncoTargets and therapy.

VARIANT (3:21) TRANSLOCATION AND MEGAKARYOCYTIC INVOLVEMENT IN BLASTIC CRISIS OF PHILADELPHIA POSITIVE CHRONIC MYELOID LEUKAEMIA

A. Aventín, A. Delannoy, C. Mecucci, 1989, British journal of haematology.

Combined trisomy 1q and monosomy 7q due to translocation 1;7 in myelodysplastic syndromes.

G. Tricot, C. Mecucci, H. van den Berghe, 1985, Cancer genetics and cytogenetics.

Submicroscopic deletions in 5 q-associated malignancies

P. Marynen, C. Mecucci, M. Martelli, 2004 .

Molecular analysis of Fanconi anemia: the experience of the Bone Marrow Failure Study Group of the Italian Association of Pediatric Onco-Hematology

S. Perrotta, C. Mecucci, A. Savoia, 2014, Haematologica.

Activating somatic and germline TERT promoter variants in myeloid malignancies

S. Colla, Valeria Nofrini, C. Mecucci, 2020, Leukemia.

dup(12)(q13→qter) in two t(14;18)‐negative follicular b‐non‐hodgkin's lymphomas

P. Marynen, C. Mecucci, C. de Wolf‐Peeters, 1992, Genes, chromosomes & cancer.

Light chain plasmacytoid lymphocytic lymphoma

B. Falini, C. Mecucci, M. Martelli, 1981, Postgraduate medical journal.

14Q+ CHROMOSOME MARKER IN A T‐CELL‐RICH B‐CELL LYMPHOMA

B. Falini, C. Mecucci, M. Martelli, 1996, The Journal of pathology.

Rearrangements of immunoglobulin and TCR genes in lymphoid blast crisis of Ph + chronic myeloid leukaemia

P. Cin, C. Mecucci, M. Stul, 1990 .

A new subtype of pre-B acute lymphoblastic leukemia with t(5;12)(q31q33;p12), molecularly and cytogenetically distinct from t(5;12) in chronic myelomonocytic leukemia.

P. Marynen, A. Aventín, C. Mecucci, 1997, Blood.

A new t(2;5) translocation in a null cell type CD30 positive anaplastic large cell lymphoma case.

C. Mecucci, C. de Wolf‐Peeters, L. Michaux, 1995, Leukemia.

Trisomy 12 does not correlate with EBV infection in chronic B-cell leukemias.

C. Mecucci, M. Stul, J. Cassiman, 1995, Cancer genetics and cytogenetics.

Cytogenetics and immunophenotype.

C. Mecucci, H. van den Berghe, 1994, Leukemia & lymphoma.

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma.

Alexander V Penson, L. Pasqualucci, R. Rabadán, 2018, Blood.

3q-, 3q+ anomaly in malignant proliferations in humans.

G. Tricot, C. Mecucci, H. van den Berghe, 1983, Cancer Genetics and Cytogenetics.

A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome

P. Marynen, C. Mecucci, M. Martelli, 2007, Leukemia.

Cytogenetic and FISH investigations on tetrasomy 8 in ANLL.

C. Mecucci, M. Martelli, C. Matteucci, 1995, Cancer genetics and cytogenetics.

A chromosomal profile of polycythemia vera.

G. Tricot, C. Mecucci, H. van den Berghe, 1987, Cancer genetics and cytogenetics.

Characterization of a new case of trisomy 8 in acute lymphoblastic leukemia.

C. Mecucci, A. Angioni, D. Rosati, 1994, Cancer genetics and cytogenetics.

4q12 translocations with GSX2 expression identify a CD7+ acute myeloid leukaemia subset

C. Mecucci, C. Storlazzi, G. Barba, 2015, British journal of haematology.

Translocation (11;15)(q23;q14) in three patients with acute non-lymphoblastic leukemia (ANLL): clinical, cytogenetic and molecular studies.

C. Mecucci, M. Stul, L. Michaux, 1995, Leukemia.

The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberration in different hematological malignancies.

P. Marynen, C. Mecucci, H. van den Berghe, 1996, Cytogenetics and cell genetics.

CD5-Negative Primary Mantle Cell Lymphoma Presenting with a Bilateral Conjunctival Mass: A Potential Diagnostic Pitfall

S. Ascani, C. Mecucci, F. Sanguedolce, 2023, Current oncology.

Philadelphia chromosome-positive chronic myelogenous leukemia in treated Hodgkin's disease.

C. Mecucci, M. Stul, J. Cassiman, 1990, Cancer genetics and cytogenetics.

Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations.

S. Chiaretti, C. Mecucci, G. Basso, 2014, Blood.

A common 93-kb duplicated DNA sequence at 1q21.2 in acute lymphoblastic leukemia and Burkitt lymphoma.

C. Mecucci, M. Martelli, P. Gorello, 2007, Cancer genetics and cytogenetics.

Further characterization of morphologically defined typical and atypical CLL: a clinical, immunophenotypic, cytogenetic and prognostic study on 390 cases

Robert Vlietinck, Herman Van den Berghe, C. Mecucci, 1997, British journal of haematology.

Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations

B. Falini, C. Mecucci, M. Martelli, 2006, Leukemia.

Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype.

B. Falini, C. Mecucci, M. Martelli, 2005, Blood.

Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance.

Natalia Meani, Myriam Alcalay, Pier Giuseppe Pelicci, 2005, Blood.

C-kit mutations in core binding factor leukemias.

P. Peterlongo, C. Mecucci, R. Cairoli, 2000, Blood.

Full haplotype-mismatched hematopoietic stem-cell transplantation: a phase II study in patients with acute leukemia at high risk of relapse.

C. Mecucci, M. Martelli, L. Ruggeri, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Comprehensive analysis of mitochondrial and nuclear DNA variations in patients affected by hemoglobinopathies: A pilot study

Valeria Nofrini, C. Mecucci, P. Gorello, 2020, PloS one.

Amylase‐producing IgD‐type multiple myeloma

J. Hamels, A. Delannoy, C. Mecucci, 1992, Journal of internal medicine.

NOTCH1 PEST domain mutation is an adverse prognostic factor in B‐CLL

I. Screpanti, C. Mecucci, M. Martelli, 2010, British journal of haematology.

Microdissection and FISH investigations in acute myeloid leukemia: a step forward to full identification of complex karyotypic changes.

P. Marynen, J. Vermeesch, C. Mecucci, 2000, Cancer genetics and cytogenetics.

European standard clinical practice - Key issues for the medical care of individuals with familial leukemia.

F. Solé, J. Fitzgibbon, C. Mecucci, 2023, European journal of medical genetics.

Genomic gain at 6p21: a new cryptic molecular rearrangement in secondary myelodysplastic syndrome and acute myeloid leukemia

P. Marynen, A. Aventín, C. Mecucci, 2006, Leukemia.

T-Cell Acute Lymphoblastic Leukemia: Biomarkers and Their Clinical Usefulness

C. Mecucci, P. Gorello, R. la Starza, 2021, Genes.

Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia

J. Soulier, E. Clappier, C. Mecucci, 2015, Haematologica.

Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

Dominique Leroux, Peter Marynen, Eric Lippert, 2008, The Journal of experimental medicine.

BCL‐6 EXPRESSION IN REACTIVE LYMPHOID TISSUE AND IN B‐CELL NON‐HODGKIN'S LYMPHOMAS

S. Pittaluga, W. V. D. Van de Ven, C. Mecucci, 1996, The Journal of pathology.

Blast crisis Ph+ chronic myeloid leukemia with NUP98/HOXA13 up-regulating MSI2

C. Mecucci, G. Barba, V. Pierini, 2014, Molecular Cytogenetics.

Surfaceome interrogation using an RNA-seq approach highlights leukemia initiating cell biomarkers in an LMO2 T cell transgenic model

P. Kearns, C. Mecucci, T. Rabbitts, 2019, Scientific Reports.

Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice.

S. Minucci, P. Pelicci, M. Odero, 2007, The Journal of clinical investigation.

Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias.

Brunangelo Falini, Maria Paola Martelli, Niccolò Bolli, 2007, Haematologica.

Clinico-biologic features and treatment outcome of adult pro-B-ALL patients enrolled in the GIMEMA 0496 study: absence of the ALL1/AF4 and of the BCR/ABL fusion genes correlates with a significantly better clinical outcome.

R. Foà, A. Vitale, F. Mandelli, 2003, Blood.

A prospective study of residual-disease monitoring of the ALL1/AF4 transcript in patients with t(4;11) acute lymphoblastic leukemia.

M. Mancini, R. Foà, F. Mandelli, 2000, Blood.

A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol.

R. Foà, A. Vitale, M. Vignetti, 2005, Blood.

T-Cell Lymphoblastic Lymphoma Arising in the Setting of Myeloid/Lymphoid Neoplasms with Eosinophilia: LMO2 Immunohistochemistry as a Potentially Useful Diagnostic Marker

S. Pileri, S. Ascani, E. Sabattini, 2021, Cancers.

BCL3 rearrangement and t(14;19)(q32;q13) in lymphoproliferative disorders

C. Mecucci, M. Stul, Jesús M. Hernández, 1996, Genes, chromosomes & cancer.

Diagnosis, classification, and cytogenetics of myelodysplastic syndromes.

C. Mecucci, C. Preudhomme, P. Fenaux, 1998, Haematologica.

Myelodysplastic Syndromes Myelodysplastic syndromes : recent advances

M. Cazzola, C. Mecucci, F. Locatelli, 2001 .

NUP98/11p15 translocations affect CD34+ cells in myeloid and T lymphoid leukemias.

A. Vitale, B. Beverloo, Valeria Nofrini, 2015, Leukemia research.

NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15).

A. Veronese, M. Negrini, C. Mecucci, 2002, Blood.

P190 BCR/ABL transcript in a case of Philadelphia-positive multiple myeloma.

C. Mecucci, M. Stul, P. Martiat, 1990, Leukemia.

Acute lymphoblastic leukaemia in Noonan syndrome

R. Foà, C. Mecucci, F. Aversa, 2006, British journal of haematology.

High grade B-cell lymphoma with MYC, BCL2 and/or BCL6 rearrangements: unraveling the genetic landscape of a rare aggressive subtype of non-Hodgkin lymphoma

S. Ascani, C. Mecucci, G. Martinelli, 2022, Leukemia & lymphoma.

The myelodysplastic syndromes

Valeria Nofrini, C. Mecucci, V. D. Battista, 2016 .

Regions of juxtaposition in unbalanced 1q rearrangements of malignant hemopathies

A. Aventín, C. Mecucci, S. Ciolli, 2001, Leukemia.

Increased Plasma Levels of lncRNAs LINC01268, GAS5 and MALAT1 Correlate with Negative Prognostic Factors in Myelofibrosis

M. Voso, C. Mecucci, M. Luppi, 2021, Cancers.

Molecular features of primary MDS with cytogenetic changes.

C. Mecucci, 1998, Leukemia research.

Molecular delineation of 13q deletion boundaries in 20 patients with myeloid malignancies.

A. Aventín, C. Mecucci, M. Martelli, 1998, Blood.

RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications

R. Foà, S. Chiaretti, A. Vitale, 2016, Haematologica.

Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults

R. Foà, S. Chiaretti, A. Vitale, 2010, Haematologica.

Characterization of ABL1 expression in adult T-cell acute lymphoblastic leukemia by oligonucleotide array analysis.

E. Ghia, R. Foà, S. Chiaretti, 2007, Haematologica.

CSNK1A1 mutations and gene expression analysis in myelodysplastic syndromes with del(5q)

M. Calasanz, C. Mecucci, P. Fenaux, 2015, British journal of haematology.

Unusual t(3;12)(q28;q13) in childhood acute lymphoblastic leukemia.

C. Mecucci, A. Angioni, D. Rosati, 1991, Cancer genetics and cytogenetics.

Incidence and significance of cryptic chromosome aberrations detected by fluorescence in situ hybridization in acute myeloid leukemia with normal karyotype

M. Mancini, C. Mecucci, A. Cuneo, 2002, Leukemia.

CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12

C. Lottaz, C. Buske, S. Bohlander, 2012, Leukemia.

Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia.

P. Marynen, A. Hagemeijer, R. Foà, 2002, Cancer research.

Genetic susceptibility and familial malignant mesothelioma

S. Knuutila, C. Mecucci, V. Ascoli, 2001, The Lancet.

Typical genomic imbalances in primary MALT lymphoma of the orbit

P. Galieni, C. Mecucci, M. Martelli, 2003, The Journal of pathology.

Different mechanisms lead to a karyotypically identical t(20;21) in myelodysplastic syndrome and in acute myelocytic leukemia.

C. Mecucci, M. Martelli, C. Matteucci, 2003, Cancer genetics and cytogenetics.

Interpretation of the complex karyotype and identification of a new 6p amplicon by integrated comparative genomic hybridization and fluorescence in situ hybridization on the U937-I cell line.

P. Marynen, C. Mecucci, A. Orlacchio, 2002, Cancer Genetics and Cytogenetics.

Regression of lymphoproliferative disorder after treatment for hepatitis C virus infection in a patient with partial trisomy 3, Bcl-2 overexpression, and type II cryoglobulinemia.

C. Mecucci, J. Kay, C. Matteucci, 2002, Blood.

Clonal eosinophils are a morphologic hallmark of ETV6/ABL1 positive acute myeloid leukemia.

P. Pelicci, C. Mecucci, M. Martelli, 2002, Haematologica.

Fusion of ETV6 to GOT1 in a case with myelodysplastic syndrome and t(10;12)(q24;p13).

P. Marynen, A. Hagemeijer, C. Mecucci, 2006, Haematologica.

Fluorescence in situ hybridization characterization of new translocations involving TEL (ETV6) in a wide spectrum of hematologic malignancies.

P. Marynen, A. Hagemeijer, C. Mecucci, 1998, Blood.

Multipotent stem cell involvement in megakaryoblastic leukemia: cytologic and cytogenetic evidence in 15 patients.

C. Mecucci, P. Martiat, A. Cuneo, 1989, Blood.

Lineage switch from pro-B acute lymphoid leukemia to acute myeloid leukemia in a case with t(12;17)(p13;q11)/TAF15–ZNF384 rearrangement

R. Foà, A. Vitale, C. Mecucci, 2013, Leukemia and Lymphoma.

Trisomy 12 is uncommon in typical chronic lymphocytic leukaemias

C. Mecucci, M. Stul, H. Berghe, 1994, British journal of haematology.

Chromosome Abnormalities in Cutaneous B-Cell Lymphomas

C. Mecucci, M. Stul, J. Cassiman, 1994 .

OKT8-positive T-cell lymphoma associated with a chromosome rearrangement t(2;17) possibly involving the T8 locus.

C. Mecucci, H. van den Berghe, 1985, The New England journal of medicine.

The 5q-anomaly.

G. Tricot, C. Mecucci, H. van den Berghe, 1985, Cancer genetics and cytogenetics.

HUGO Gene Nomenclature Committee (HGNC) recommendations for the designation of gene fusions

R. Verhaak, C. Antonescu, B. Johansson, 2021, Leukemia.

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM / AF 10-positive leukemia

W. Hiddemann, S. Bohlander, C. Buske, 2022 .

Trisomy 3 in marginal zone B‐cell lymphoma: a study based on cytogenetic analysis and fluorescence in situ hybridization

S. Pittaluga, C. Mecucci, C. de Wolf‐Peeters, 1996, British journal of haematology.

MDR1 protein expression is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia.

R. Foà, A. Vitale, M. Vignetti, 2002, Blood.

Translocation t(8;16)(p11;p13) in acute non-lymphocytic leukemia: report on two new cases and review of the literature.

C. Mecucci, M. Stul, L. Michaux, 1996, Leukemia & lymphoma.

Translocation t(8;10)(q12;p14) in lymphoproliferative disorders.

C. Mecucci, H. van den Berghe, J. Michaux, 1984, Leukemia research.

Combined translocation with ZNF198-FGFR1 gene fusion and deletion of potential tumor suppressors in a myeloproliferative disorder.

D. Birnbaum, F. Birg, C. Mecucci, 2007, Cancer genetics and cytogenetics.

Translocation (11;14): A cytogenetic anomaly associated with B‐cell lymphomas of non‐follicle centre cell lineage

J. Delabie, C. Mecucci, J. J. van den Oord, 1991, The Journal of pathology.

Two Translocations: a Follicular Variant 2; 18 and a Burkitt 8;14 in a Small Non Cleaved Non Hodgkin's Lymphoma.

C. Mecucci, C. Wolf‐peeters, H. van den Berghe, 1991, Leukemia & lymphoma.

Molecular breakpoints of t(11;14)(q13;q32) in multiple myeloma.

C. Mecucci, M. Stul, J. Cassiman, 1995, Cancer genetics and cytogenetics.

AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features.

A. Kohlmann, T. Haferlach, M. Vignetti, 2009, Blood.

ACUTE MYELOID LEUKEMIA CARRYING CYTOPLASMIC / MUTATED NUCLEOPHOSMIN ( NPMc + AML ) : BIOLOGICAL AND CLINICAL FEATURES

B. Falini, C. Mecucci, M. Martelli, 2006 .

Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification.

S. Pileri, L. Pasqualucci, N. Bolli, 2006, Blood.

Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia.

Myriam Alcalay, Giovanni Roti, Brunangelo Falini, 2006, Blood.

Double CEBPE-IGH rearrangement due to chromosome duplication and cryptic insertion in an adult with B-cell acute lymphoblastic leukemia.

A. Vitale, Valeria Nofrini, C. Mecucci, 2011, Cancer genetics.

Characterization of a recurrent translocation t(2;3)(p15–22;q26) occurring in acute myeloid leukaemia

M. Mancini, M. Rocchi, G. Specchia, 2006, Leukemia.

Linking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia.

Valeria Nofrini, C. Mecucci, F. Aversa, 2013, Leukemia research.

Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia

R. Foà, S. Chiaretti, C. Mecucci, 2016, Haematologica.

Rare HRAS1 alleles outside the VTR region in lymph nodes from patients with malignant lymphoma.

C. Mecucci, M. Stul, J. Cassiman, 1993, Cancer genetics and cytogenetics.

NUP98 fusion oncoproteins promote aneuploidy by attenuating the mitotic spindle checkpoint.

C. Mecucci, P. Gorello, V. Salsi, 2014, Cancer research.

Molecular and Cellular Pathobiology NUP 98 Fusion Oncoproteins Promote Aneuploidy by Attenuating the Mitotic Spindle Checkpoint

C. Mecucci, P. Gorello, V. Salsi, 2014 .

Use of dual-color interphase FISH for the detection of inv(16) in acute myeloid leukemia at diagnosis, relapse and during follow-up: a study of 23 patients

M. Mancini, A. Hagemeijer, C. Mecucci, 2000, Leukemia.

Genomic organization of human JAK2 and mutation analysis of its JH2-domain in leukemia

P. Marynen, T. Voet, A. Aventín, 1999, Cytogenetic and Genome Research.

Submicroscopic deletions in 5q- associated malignancies.

P. Marynen, C. Mecucci, M. Martelli, 2004, Haematologica.

Adult T-cell acute lymphoblastic leukemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol.

R. Foà, P. Mazza, A. Vitale, 2006, Blood.

Cytogenetic and clinical investigations in 76 cases with therapy-related leukemia and myelodysplastic syndrome.

C. Mecucci, H. van den Berghe, M. Boogaerts, 1989, Cancer genetics and cytogenetics.

Cytogenetic follow-up after allogeneic bone-marrow transplantation for Ph1-positive chronic myelogenous leukemia.

M. Mancini, C. Mecucci, W. Arcese, 1990, Bone marrow transplantation.

Cryptic insertion producing two NUP98/NSD1 chimeric transcripts in adult refractory anemia with an excess of blasts

A. Veronese, M. Negrini, C. Mecucci, 2004, Genes, chromosomes & cancer.

Isodicentric (X)(q13) in haematological malignancies: presentation of five new cases, application of fluorescence in situ hybridization (FISH) and review of the literature

C. Mecucci, J. Dierlamm, L. Michaux, 1995, British journal of haematology.

Congenital and Acquired Chronic Neutropenias: Challenges, Perspectives and Implementation of the EuNet-INNOCHRON Action

J. Palmblad, K. Stamatopoulos, C. Mecucci, 2020, HemaSphere.

Acute Myeloid Leukemia: Impact on Who Classification Mutated Nucleophosmin Detects Clonal Multilineage Involvement In

L. Pasqualucci, N. Bolli, F. Mandelli, 2022 .

Announcements

C. Mecucci, J. Bennett, G. Juliusson, 1990 .

Trisomy 3 is a consistent chromosome change in malignant lymphoproliferative disorders preceded by cold agglutinin disease

A. Delannoy, C. Mecucci, M. Stul, 1995, British journal of haematology.

Genomic and clinical findings in myeloid neoplasms with PDGFRB rearrangement

C. Mecucci, A. Cuneo, M. Luppi, 2021, Annals of Hematology.

The importance of cytogenetic and molecular analyses in eosinophilia-associated myeloproliferative neoplasms: an unusual case with normal karyotype and TNIP1- PDGFRB rearrangement and overview of PDGFRB partner genes

D. D. Giacomo, C. Mecucci, R. Marasca, 2017, Leukemia & lymphoma.

Molecular cytogenetic findings in a four-way t(1;12;5;12)(p36;p13;q33;q24) underlying the ETV6-PDGFRB fusion gene in chronic myelomonocytic leukemia.

P. Marynen, C. Mecucci, M. Martelli, 2007, Cancer genetics and cytogenetics.

TPM3/PDGFRB fusion transcript and its reciprocal in chronic eosinophilic leukemia

C. Mecucci, M. Martelli, P. Gorello, 2006, Leukemia.

The hypereosinophilic syndrome: fluorescence in situ hybridization detects the del(4)(q12)-FIP1L1/PDGFRA but not genomic rearrangements of other tyrosine kinases.

P. Marynen, A. Aventín, C. Mecucci, 2005, Haematologica.

The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia – analysis of 848 patients

M. Gobbi, R. Fanin, F. Mandelli, 2001, Leukemia.

VARIANT t(2;18) TRANSLOCATION IN A BURKITT CONVERSION OF FOLLICULAR LYMPHOMA

A. Aventín, C. Mecucci, S. Brunet, 1990, British journal of haematology.

Philadelphia‐like translocation t(9;22)(q34;q11) found in a follicular lymphoma involving not BCR and ABL but IGL‐mediated rearrangement of an unknown gene on 9q34

S. Pittaluga, C. Mecucci, C. de Wolf‐Peeters, 1997, Genes, chromosomes & cancer.

Blastic phase of Ph1-positive chronic myeloid leukemia and t(3;21) [letter]

A. Aventín, C. Mecucci, H. Berghe, 1988 .

Chronic eosinophilic leukaemia with ETV6‐NTRK3 fusion transcript in an elderly patient affected with pancreatic carcinoma

B. Falini, C. Mecucci, R. Marasca, 2011, European journal of haematology.

3q aberration and monosomy 7 in ANLL presenting with high platelet count and diabetes insipidus.

C. Mecucci, M. Martelli, A. Tabilio, 1994, Haematologica.

Thrombocytosis and inv(3)(q21q26) [letter]

C. Mecucci, H. Berghe, 1983 .

Clinical and cytogenetic findings in monocyte--macrophage system malignancies with initial spontaneous regression.

C. Mecucci, M. Martelli, A. Tabilio, 1983, Cancer genetics and cytogenetics.

A translocation (8;14) in a cutaneous large B-cell lymphoma.

C. Mecucci, M. Stul, J. Cassiman, 1993, American journal of clinical pathology.

Clustering of genomic breakpoints at the MLL locus in therapy‐related acute leukemia with t(4;11)(q21;q23)

B. Falini, F. Lo‐Coco, C. Mecucci, 2014, Genes, chromosomes & cancer.

Partial duplication of the MLL oncogene in patients with aggressive acute myeloid leukemia.

C. Mecucci, M. Martelli, C. Preudhomme, 2004, Haematologica.

Comparison between Sickle Cell Disease Patients and Healthy Donors: Untargeted Lipidomic Study of Erythrocytes

C. Mecucci, R. Pellegrino, P. Gorello, 2023, International journal of molecular sciences.

The Molecular Spectrum of β- and α-Thalassemia Mutations in Non-Endemic Umbria, Central Italy

C. Mecucci, P. Gorello, A. Piga, 2016, Hemoglobin.

A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function.

C. Mecucci, L. Ruggeri, U. Grohmann, 2020, Journal of autoimmunity.

6p+ and 9q- in two chromosomally distinct clones occurring in a case of myelodysplastic syndrome evolving to acute nonlymphocytic leukemia.

C. Mecucci, P. Bernabei, H. van den Berghe, 1988, Cancer genetics and cytogenetics.

Variant translocation t(15q;17q) accompanying a promyelocytic accelerated phase of Ph-positive chronic myeloid leukemia.

C. Mecucci, H. van den Berghe, A. Louwagie, 1987, Cancer genetics and cytogenetics.

acute myeloid leukemia mutations in (NPM) Immunohistochemistry predicts nucleophosmin

N. Bolli, E. Ghia, F. Mandelli, 2011 .

Accumulation of Nucleophosmin Leukemic Mutants Signals of Different Strength Ensure Cytoplasmic Born to Be Exported : COOH-Terminal Nuclear Export

N. Bolli, B. Falini, C. Mecucci, 2007 .

Inversions of chromosome 12 in human malignancies.

C. Mecucci, H. van den Berghe, C. Doyen, 1987, Cancer genetics and cytogenetics.

Molecular cytogenetics localizes two new breakpoints on 11q23.3 and 21q11.2 in myelodysplastic syndrome with t(11;21) translocation

G. Evans, C. Mecucci, L. Selleri, 1999, Genes, chromosomes & cancer.

genes involved in stem cell maintenance shows a distinct gene expression profile characterized by up-regulation of Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+AML)

E. Venturini, C. Mecucci, L. Luzi, 2013 .

Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in acute myeloid leukemia.

B. Falini, C. Mecucci, M. Martelli, 2006, The Journal of molecular diagnostics : JMD.

A Valid Approach for Identifying NPM1 Mutations in Acute Myeloid Leukemia

B. Falini, C. Mecucci, M. Martelli, 2006 .

A novel germline mutation in CDK4 codon 24 associated to familial melanoma

C. Mecucci, I. Bottillo, A. Paiardini, 2018, Clinical genetics.

NPM1 mutations and cytoplasmic nucleophosmin are mutually exclusive of recurrent genetic abnormalities: a comparative analysis of 2562 patients with acute myeloid leukemia

S. Pileri, T. Haferlach, B. Falini, 2008, Haematologica.

Metachronous cardiac and cerebral sarcomas: case report with focus on molecular findings and review of the literature.

C. Mecucci, R. la Starza, G. Montesi, 2015, Human pathology.

Phytohemagglutinin-conditioned medium modulates adherence properties and morphology of hairy cells.

B. Falini, C. Mecucci, J. Cassiman, 1986, Leukemia research.

Clinical management of primary non-acute promyelocytic leukemia acute myeloid leukemia: practice Guidelines by the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation

M. Vignetti, C. Mecucci, G. Martinelli, 2009, Haematologica.

Trisomy-4 Identifies a Subset of Acute Nonlymphocytic Leukemias

G. Tricot, A. Delannoy, C. Mecucci, 1986 .

A PDGFRB-positive acute myeloid malignancy with a new t(5;12)(q33;p13.3) involving the ERC1 gene

R. Foà, C. Mecucci, M. Martelli, 2008, Leukemia.

Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia.

C. Mecucci, P. Gorello, J. Schwaller, 2008, Blood.

Characteristics and outcome of therapy‐related myeloid neoplasms: Report from the Italian network on secondary leukemias

M. Gobbi, M. Voso, L. Pagano, 2015, American journal of hematology.

Hypereosinophilic syndrome and cyclic oscillations in blood cell counts. A clonal disorder of hematopoiesis originating in a pluripotent stem cell.

M. Cazzola, C. Mecucci, L. Malcovati, 2004, Haematologica.

Lack of efficacy of convalescent plasma in COVID‐19 patients with concomitant hematological malignancies: An Italian retrospective study

F. Gherlinzoni, C. Mecucci, F. Lanza, 2022, Hematological Oncology.

Trisomy 6 is the hallmark of a dysplastic clone in bone marrow aplasia.

C. Mecucci, M. Martelli, H. van den Berghe, 1998, Cancer genetics and cytogenetics.

Breakpoints of 11q25 in three similar cases of B non Hodgkin's lymphoma.

C. Mecucci, H. van den Berghe, J. Michaux, 1991, Leukemia & lymphoma.

Rare t(1;11)(q23;p15) in therapy-related myelodysplastic syndrome evolving into acute myelomonocytic leukemia: a case report and review of the literature.

C. Mecucci, R. Alsabeh, P. Gorello, 2007, Cancer Genetics and Cytogenetics.

Human homeobox gene HOXC13 is the partner of NUP98 in adult acute myeloid leukemia with t(11;12)(p15;q13)

Massimo Negrini, Pier Giuseppe Pelicci, M. Negrini, 2003, Genes, chromosomes & cancer.

Molecular evaluation of the NUP98/RAP1GDS1 gene frequency in adults with T-acute lymphoblastic leukemia.

R. Foà, F. Mandelli, C. Mecucci, 2001, Haematologica.

Distinct genomic events in the myeloid and lymphoid lineages in simultaneous presentation of chronic myeloid leukemia and B-chronic lymphocytic leukemia

S. Sacchi, C. Mecucci, M. Martelli, 2002, Leukemia.

Blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia: a shared clonal origin

B. Falini, S. Ascani, C. Mecucci, 2017, Leukemia.

Idiopathic Hypereosinophilic Syndrome (HES) with FIP1L1-PDGFRA Rearrangement Can Be Effectively Treated with Imatinib.

S. Pileri, M. Cazzola, M. Gobbi, 2004 .

HCV-associated lymphomas.

C. Mecucci, P. Farci, M. Fiorilli, 2003, Reviews in clinical and experimental hematology.

Trisomy 8 in PDGFRB-negative cells in a patient with imatinib-sensitive chronic myelomonocytic leukemia and t(5;16)(q33;p13), PDGFRB-NDE1 fusion.

C. Mecucci, A. Cuneo, P. Gorello, 2009, Cancer genetics and cytogenetics.

Multiple chromosomally distinct cell populations in myelodysplastic syndromes and their possible significance in the evolution of the disease

G. Tricot, C. Mecucci, H. Berghe, 1986, British journal of haematology.

Translocation t(3;17)(q26;q22): a marker of acute disease in myeloproliferative disorders?

C. Mecucci, H. van den Berghe, M. Boogaerts, 1984, Cancer genetics and cytogenetics.

EVOLUTION OF THE MYELODYSPLASTIC SYNDROMES

G. Tricot, C. Mecucci, H. van den Berghe, 1986, British journal of haematology.

B-cell non-Hodgkin's lymphomas of follicle mantle lineage: part of a biological spectrum?

C. Mecucci, J. J. van den Oord, C. de Wolf‐Peeters, 1991, Leukemia.

Germline GATA2 variant disrupting endothelial eNOS function and angiogenesis can be restored by c-Jun/AP-1 upregulation

C. Mecucci, P. Gresele, C. Matteucci, 2021, Haematologica.

5q- in a case of blastic phase chronic myeloid leukemia.

C. Mecucci, E. Donti, G. Venti, 1985, Cancer genetics and cytogenetics.

Herpesvirus 8-negative primary effusion lymphoma associated with hepatitis C virus [3] (multiple letters)

C. Mecucci, V. Ascoli, R. Ichinohasama, 2000 .

Herpesvirus 8-negative primary effusion lymphoma associated with hepatitis C virus.

C. Mecucci, F. Lo Coco, V. Ascoli, 2000, American Journal of Surgical Pathology.

A Novel t(5;7)(q31;q21)/CDK6::IL3 in Immature T-cell Acute Lymphoblastic Leukemia With IL3 Expression and Eosinophilia

E. Sabattini, C. Mecucci, L. Ruggeri, 2022, HemaSphere.

The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling.

H. Fröhlich, D. Huylebroeck, C. Mecucci, 2017, Blood.

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

C. Mecucci, G. Cavaletti, S. Citterio, 2020, Nature Communications.

Chronic lymphocytic leukaemia Is terminal del(14)(q24) a new marker for prognostic stratification?

C. Mecucci, M. Martelli, C. Matteucci, 2006, Leukemia research.

patients enrolled in the GIMEMA LAL 0496 protocol presentation and correlation with response to induction treatment in Adult T-cell acute lymphoblastic leukemia: biologic profile at

P. Mazza, A. Vitale, M. Vignetti, 2013 .

The Gimema Lal 0496 Protocol and Correlation with Response to Induction Treatment in Patients Enrolled in Adult T-cell Acute Lymphoblastic Leukemia: Biologic Profile at Presentation

R. Foà, P. Mazza, A. Vitale, 2022 .

About the t(8;13)(p11;q12) clinico-pathologic entity.

C. Mecucci, J. Dierlamm, L. Michaux, 1996, Blood.

A novel gene, AF-1p, fused to HRX in t(1;11)(p32;q23), is not related to AF-4, AF-9 nor ENL.

R. Berger, C. Mecucci, H. van den Berghe, 1994, Oncogene.

CIZ gene rearrangements in acute leukemia: report of a diagnostic FISH assay and clinical features of nine patients

P. Marynen, A. Hagemeijer, R. Foà, 2005, Leukemia.

Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation

Diana M. Mitrea, Chunxu Qu, J. Klco, 2021, Cancer discovery.

Detection of BCR/ABL rearrangements in adult acute lymphoblastic leukemia using a highly sensitive interphase fluorescence in situ hybridization method (D-FISH).

R. Foà, C. Mecucci, G. Cimino, 2001, The hematology journal : the official journal of the European Haematology Association.

11q23 involvement in a complex insertion (10; 11) in acute monocytic leukemia.

G. Tricot, C. Mecucci, H. van den Berghe, 1986, Leukemia research.

A Prospective Study in Ph+ Chronic Myeloid Leukemia (CML) Patients Showing That Interphase Fluorescence in Situ Hybridization (FISH) Is Effective as Conventional Cytogenetics for Definition of Cytogenetic Response. Correlation with Molecular Response (by the GIMEMA CML WP).

M. Mancini, M. Baccarani, C. Mecucci, 2006 .

ider(9)(q10)t(9;22)(q34;q11) is a recurrent chromosomal abnormality in acute lymphoblastic leukemia and lymphatic blastic phase of chronic myelogenous leukemia.

N. Kröger, C. Mecucci, J. Dierlamm, 1996, Cancer genetics and cytogenetics.

T-lymphoid/myeloid biphenotypic leukemia morphologically resembling malignant histiocytosis. Immunological, cytogenetic and molecular studies.

B. Falini, C. Mecucci, M. Martelli, 1993, Haematologica.

The role of BCR/ABL isoforms in the presentation and outcome of patients with Philadelphia-positive acute lymphoblastic leukemia: a seven-year update of the GIMEMA 0496 trial.

R. Foà, F. Mandelli, C. Mecucci, 2006, Haematologica.

New MLLT 10 gene recombinations in pediatric T-acute lymphoblastic leukemia

D. D. Giacomo, C. Mecucci, G. Kronnie, 2013 .

Mast Cell Leukemia: An Update with a Practical Review

S. Ascani, C. Mecucci, F. Sanguedolce, 2023, Cancers.

Trisomy 4 identifies a subset of acute nonlymphocytic leukemias.

G. Tricot, A. Delannoy, C. Mecucci, 1986, Blood.

The origin of trisomy 12 in B-cell chronic lymphocytic leukemia.

A. Delannoy, C. Mecucci, H. van den Berghe, 1988, Cancer genetics and cytogenetics.

Isochromosome 17q- in acute promyelocytic leukemia. Molecular characterization by fluorescence in situ hybridization.

A. Aventín, C. Mecucci, G. Martín-Henao, 1994, Cancer genetics and cytogenetics.

Design of a comprehensive fluorescence in situ hybridization assay for genetic classification of T-cell acute lymphoblastic leukemia.

R. Foà, S. Chiaretti, A. Vitale, 2020, The Journal of molecular diagnostics : JMD.

Prognostic impact of genetic characterization in the GIMEMA LAM99P multicenter study for newly diagnosed acute myeloid leukemia

Paola Fazi, Marco Vignetti, Pier Giuseppe Pelicci, 2008, Haematologica.

Dual-color split signal fluorescence in situ hybridization assays for the detection of CALM/AF10 in t(10;11)(p13;q14-q21)-positive acute leukemia.

S. Bohlander, A. Aventín, C. Mecucci, 2006, Haematologica.

Molecular analysis of Fanconi anemia: the experience of the Bone Marrow Failure Study Group of the Italian Association of Pediatric Onco-Hematology

S. Perrotta, C. Mecucci, A. Savoia, 2014, Haematologica.

CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12

C. Lottaz, C. Buske, S. Bohlander, 2012, Leukemia.

Circulating extracellular particles from severe COVID-19 patients show altered profiling and innate lymphoid cell-modulating ability

V. Ranieri, C. Mecucci, T. Lazzarotto, 2023, Frontiers in Immunology.

New Recurrently Mutated Genes in Classical Hodgkin Lymphoma Revealed By Whole-Exome Sequencing of Microdissected Tumor Cells

L. Pasqualucci, R. Rabadán, B. Falini, 2016 .

Partial deletions of long arm of chromosome 6: biologic and clinical implications in adult acute lymphoblastic leukemia

G. Specchia, R. Foà, F. Mandelli, 2002, Leukemia.

AML1/MTG16 fusion gene from a t(16;21)(q24;q22) translocation in treatment-induced leukemia after breast cancer.

C. Mecucci, M. Martelli, C. Matteucci, 2001, Haematologica.

Small B cell NHL and their leukemic counterpart: differences in subtyping and assessment of leukemic spread.

S. Pittaluga, C. Mecucci, C. de Wolf‐Peeters, 1996, Leukemia.

Aberrant subcellular expression of nucleophosmin and NPM-MLF1 fusion protein in acute myeloid leukaemia carrying t(3;5): A comparison with NPMc+ AML

N. Bolli, B. Falini, C. Mecucci, 2006, Leukemia.

Implication of MAPK1/MAPK3 signalling pathway in t(8;9)(p22;24)/PCM1‐JAK2 myelodysplastic/myeloproliferative neoplasms

C. Mecucci, F. Aversa, M. Vitale, 2013, British journal of haematology.

Genomic arrays for the identification of high-risk chronic lymphocytic leukemia: ready for prime time?

C. Mecucci, A. Cuneo, G. Rigolin, 2021, Haematologica.

A variant translocation t(2;18) in follicular lymphoma involves the 5' end of bcl-2 and Ig kappa light chain gene.

A. Aventín, C. Mecucci, C. Larsen, 1991, Oncogene.

Guiding the global evolution of cytogenetic testing for hematologic malignancies

P. D. Dal Cin, F. Solé, R. Levine, 2022, Blood.

Identification of chromosome changes in acute myeloid leukemia (AML-M2) by molecular cytogenetics.

A. Hagemeijer, C. Mecucci, M. Martelli, 1997, Cancer genetics and cytogenetics.

Philadelphia-positive T-acute lymphoblastic leukemia.

C. Mecucci, H. van den Berghe, C. Verfaillie, 1985, Cancer genetics and cytogenetics.

Role of BCL2L10 methylation and TET2 mutations in higher risk myelodysplastic syndromes treated with 5-Azacytidine

M. Vignetti, M. Voso, S. Hohaus, 2011, Leukemia.

NUP98 Fusion Proteins Are Recurrent Aberrancies in Childhood Acute Myeloid Leukemia: A Report from the AIEOP AML-2001-02 Study Group

C. Mecucci, G. Basso, F. Locatelli, 2014 .

5q- syndrome terminating in acute myeloid leukemia. Karyotype evolution and immunologic characterization of blast cells.

C. Mecucci, M. Martelli, A. Tabilio, 1988, Cancer genetics and cytogenetics.

5q-Syndrome in a patient with chronic exposure to ionizing radiation.

C. Mecucci, M. Martelli, A. Tabilio, 1982, Cancer genetics and cytogenetics.

e6a2 BCR/ABL1 fusion with cryptic der(9)t(9;22) deletions in a patient with chronic myeloid leukemia.

C. Mecucci, M. Martelli, P. Gorello, 2005, Haematologica.

Genomic integrity and mitochondrial metabolism defects in Warsaw syndrome cells: a comparison with Fanconi anemia

C. Mecucci, A. Savoia, N. Zini, 2021, Journal of cellular physiology.

The Clinical Picture of the ERCC6L2 Disease - from Bone Marrow Failure to Acute Leukemia.

J. Soulier, O. Kilpivaara, T. Vulliamy, 2023, Blood.

ZNF384 (zinc finger protein 384)

C. Mecucci, P. Gorello, Starza R La, 2011 .

MYB deregulation from a EWSR1-MYB fusion at leukemic evolution of a JAK2V617F positive primary myelofibrosis

C. Mecucci, P. Gorello, R. la Starza, 2016, Molecular Cytogenetics.

14Q+ CHROMOSOME MARKER IN A T‐CELL‐RICH B‐CELL LYMPHOMA

B. Falini, C. Mecucci, M. Martelli, 1996, The Journal of pathology.

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

W. Hiddemann, T. Haferlach, B. Falini, 2005 .

Cytoplasmic nucleophosmin in myeloid sarcoma occurring 20 years after diagnosis of acute myeloid leukaemia.

N. Bolli, B. Falini, C. Mecucci, 2006, The Lancet. Oncology.

Molecular and alternative methods for diagnosis of acute myeloid leukemia with mutated NPM1: flexibility may help

S. Pileri, B. Falini, C. Mecucci, 2010, Haematologica.

Cytoplasmic mutated nucleophosmin is stable in primary leukemic cells and in a xenotransplant model of NPMc+ acute myeloid leukemia in SCID mice

S. Pileri, N. Bolli, T. Haferlach, 2008, Haematologica.

Imatinib Mesylate Can Induce Molecular Complete Remission in Idiopathic Hypereosinophilic Syndrome (HES). A Phase II Multicentric Italian Clinical Trial.

M. Baccarani, C. Mecucci, P. Piccaluga, 2005 .

E2A-PBX1 fusion in adult acute lymphoblastic leukemia (ALL) with t(l;19) translocation: Biologic and clinical features

M. Mancini, R. Foà, A. Vitale, 2000 .

Translocation (4;11) in ALL: a new morphologic aspect?

C. Mecucci, L. Madero, M. Ferrò, 1986, Cancer genetics and cytogenetics.

t(5;10)(q33;q21)

C. Mecucci, 2011 .

Typical CBFbeta/MYH11 fusion due to insertion of the 3'-MYH11 gene into 16q22 in acute monocytic leukemia with normal chromosomes 16 and trisomies 8 and 22.

A. Aventín, J. Sierra, C. Mecucci, 2000, Cancer genetics and cytogenetics.

patients enrolled in the GIMEMA LAL 0496 protocol presentation and correlation with response to induction treatment in Adult T-cell acute lymphoblastic leukemia: biologic profile at

R. Foà, P. Mazza, A. Vitale, 2013 .

A t(9;11)(q11;p15) translocation in a myelodysplastic syndrome with erythroleukemic trait.

C. Mecucci, H. van den Berghe, A. Louwagie, 1986, Cancer Genetics and Cytogenetics.

Nanopore sequencing for the screening of myeloid and lymphoid neoplasms with eosinophilia and rearrangement of PDGFRα, PDGFRβ, FGFR1 or PCM1-JAK2

C. Mecucci, P. Guglielmelli, F. Mannelli, 2021, Biomarker research.

Erratum: Simultaneous detection of NPM1 and FLT3-ITD mutations by capillary electrophoresis in acute myeloid leukemia (Leukemia (2005) vol. 19 (1479-1482) 10.1038/sj.leu.2403846)

B. Falini, F. Lo‐Coco, C. Mecucci, 2007 .

New reciprocal translocation t(5;10)(q33;q22) associated with atypical chronic myeloid leukemia.

C. Mecucci, M. Roncalli, C. Carlo-Stella, 1999, Haematologica.

Deletion of 5q by t(5;17) in therapy-related myelodysplastic syndrome.

A. Delannoy, C. Mecucci, H. van den Berghe, 1990, Cancer genetics and cytogenetics.

5q- anomaly in lymphoid disorders.

C. Mecucci, M. Stul, A. Cuneo, 1990, Leukemia.

Myelodysplastic disorders carrying both isolated del(5q) and JAK2 V617F mutation: concise review, with focus on lenalidomide therapy

M. Voso, C. Mecucci, V. Simeon, 2014 .

FOXP1 and TP63 involvement in the progression of myelodysplastic syndrome with 5q- and additional cytogenetic abnormalities

C. Mecucci, C. Agostinelli, A. Guarini, 2014, BMC Cancer.

Variant translocation t(7;922) during lymphoid blastic crisis in a case of Ph1-positive chronic myelogenous leukemia with previous EBV infection.

C. Mecucci, H. van den Berghe, A. Louwagie, 1986, Acta haematologica.

Lineage switch from pro-B acute lymphoid leukemia to acute myeloid leukemia in a case with t(12;17)(p13;q11)/TAF15–ZNF384 rearrangement

R. Foà, A. Vitale, C. Mecucci, 2013, Leukemia & lymphoma.

Metachronous cardiac and cerebral sarcomas: case report with focus on molecular findings and review of the literature.

C. Mecucci, R. la Starza, G. Montesi, 2015, Human Pathology.

NOTCH1 PEST domain mutation is an adverse prognostic factor in B‐CLL

I. Screpanti, C. Mecucci, M. Martelli, 2010, British journal of haematology.

New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia.

C. Mecucci, P. Gorello, M. Giordan, 2013, Blood.

MN1-ETV6 fusion gene arising from MDS with 5q-.

Valeria Nofrini, C. Mecucci, P. Gorello, 2011, Leukemia research.

Practical considerations for diagnosis and management of patients and carriers.

C. Mecucci, C. Niemeyer, 2017, Seminars in hematology.

Molecular analysis of Fanconi anemia: the experience of the Bone Marrow Failure Study Group of the Italian Association of Pediatric Onco-Hematology

S. Perrotta, C. Mecucci, A. Savoia, 2014, Haematologica.

A CYTOGENETIC ANOMALY ASSOCIATED WITH B-CELL LYMPHOMAS OF NON-FOLLICLE CENTRE

C. Wolf‐Peeters, C. Mecucci, M. Stul, 2005 .

MDR1 protein expression is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia.

R. Foà, A. Vitale, M. Vignetti, 2002, Blood.

Molecular Cytogenetics Detect an Unbalanced t(2;13)(q36;q14) and PAX3–FOXO1 Fusion in Rhabdomyosarcoma With Mixed Embryonal/Alveolar Features

Valeria Nofrini, C. Mecucci, R. la Starza, 2015, Pediatric blood & cancer.

Myelodysplastic syndromes: recent advances.

M. Cazzola, C. Mecucci, F. Locatelli, 2001, Haematologica.

Translocation t(11;14) and trisomy 11q13----qter in multiple myeloma.

C. Mecucci, A. Tabilio, E. Donti, 1984, Annales de genetique.

Cytogenetic investigations in childhood chronic myelocytic leukemia.

C. Mecucci, H. van den Berghe, J. Michaux, 1986, Cancer genetics and cytogenetics.

AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation.

Diana M. Mitrea, Chunxu Qu, J. Klco, 2022, Clinical lymphoma, myeloma & leukemia.