J. Gorham

J. Seidman, A. Robling, C. Seidman, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Early post-zygotic mutations contribute to congenital heart disease

K. B. Manheimer, W. Chung, J. Seidman, 2019, bioRxiv.

In Vivo and In Vitro Methods to Identify DNA Sequence Variants that Alter RNA Splicing

Parth N. Patel, C. Seidman, J. Gorham, 2018, Current protocols in human genetics.

J. Seidman, T. Kurtz, C. Seidman, 2011, Physiological genomics.

Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors

K. B. Manheimer, W. Chung, J. Seidman, 2017, bioRxiv.

BET Bromodomain Proteins Regulate Transcriptional Reprogramming in Genetic Dilated Cardiomyopathy

Saptarsi M. Haldar, Michael A. Burke, J. Seidman, 2020, bioRxiv.

LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart

J. Seidman, W. Roberts, B. Maron, 2021, Journal of the American Heart Association.

Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers

J. Seidman, J. Spudich, R. Cooke, 2018, Proceedings of the National Academy of Sciences.

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

Catherine L. Worth, S. Teichmann, J. Seidman, 2022, Science.

An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations

J. Seidman, R. Eavey, C. Seidman, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Title : Hypertrophic Cardiomyopathy Mutations in MYBPC 3 Dysregulate Myosin : Implications for Therapy

J. Seidman, H. Watkins, H. Wakimoto, 2018 .

Neither cardiac mitochondrial DNA variation or copy number contribute to congenital heart disease risk

J. Seidman, Yufeng Shen, D. Bernstein, 2022, The American Journal of Human Genetics.

Histone deacetylase inhibitors enhance oncolytic herpes simplex virus therapy for malignant meningioma

H. Wakimoto, R. Martuza, S. Rabkin, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Multiplexed Single‐Nucleus RNA Sequencing Using Lipid‐Oligo Barcodes

J. Seidman, C. Seidman, Tarsha L Ward, 2022, Current protocols.

Molecular Genetics of Lidocaine-Containing Cardioplegia in the Human Heart During Cardiac Surgery.

J. Seidman, S. Aranki, M. Heydarpour, 2018, The Annals of thoracic surgery.

The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development.

J. Seidman, C. Seidman, J. Gorham, 2018, The Annals of thoracic surgery.

Damaging variants in FOXI3 cause microtia and craniofacial microsomia

Gloria L. Porras-Hurtado, J. Seidman, R. Eavey, 2022, Genetics in medicine : official journal of the American College of Medical Genetics.

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model

J. Seidman, L. Leinwand, N. Hübner, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere

S. Gygi, J. Seidman, J. Paulo, 2022, Circulation.

Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice.

J. Seidman, R. Lieber, C. Seidman, 2014, Human molecular genetics.

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

J. Seidman, J. Taube, D. Roden, 2016, The New England journal of medicine.

ORE identifies extreme expression effects enriched for rare variants

F. Richter, G. E. Hoffman, K. B. Manheimer, 2019, Bioinform..

poly(UG)-tailed RNAs in genome protection and epigenetic inheritance

M. Wickens, J. Seidman, Scott Kennedy, 2020, Nature.

poly(UG)-tailed RNAs in Genome Protection and Epigenetic Inheritance

M. Wickens, J. Seidman, Scott Kennedy, 2019, bioRxiv.

Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma

Monica Stanciu, H. Wakimoto, R. Martuza, 2019, Nature Communications.

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis

Gregory M. Fomovsky, Richard T. Lee, J. Seidman, 2015, Proceedings of the National Academy of Sciences.

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies

Stephan J Sanders, M. Daly, W. Chung, 2015, Science.

Genomic analyses implicate noncoding de novo variants in congenital heart disease

Kathleen M. Chen, K. B. Manheimer, G. Marth, 2020, Nature Genetics.

Cells and gene expression programs in the adult human heart

Matthias Heinig, Daniel Reichart, Sarah A. Teichmann, 2020, bioRxiv.

De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease

Michael F Swartz, K. B. Manheimer, W. Chung, 2020, Circulation. Genomic and precision medicine.

Isolation of Nuclei from Mammalian Cells and Tissues for Single‐Nucleus Molecular Profiling

J. Seidman, N. Hübner, C. Seidman, 2021, Current protocols.

5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.

J. Seidman, M. Bulyk, P. D. De Jager, 2014, The Journal of clinical investigation.

Direct Reprogramming of Non-limb Fibroblasts to Cells with Properties of Limb Progenitors

J. Seidman, C. Tabin, O. Pourquié, 2021, bioRxiv.

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice

Gregory A. Newby, J. Seidman, H. Wakimoto, 2023, Nature Medicine.

Contribution of Noncanonical Splice Variants to TTN Truncating Variant Cardiomyopathy

Parth N. Patel, J. Seidman, S. Cook, 2021, Circulation. Genomic and precision medicine.

Discovery and analyses of pathogenic variants in explanted hearts from primary cardiomyopathy patients

J. Seidman, C. Seidman, J. Gorham, 2020 .

Genetic Variants Associated With Cancer Therapy–Induced Cardiomyopathy

Parth N. Patel, J. Seidman, D. O’Regan, 2019, Circulation.

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin

Christine E Seidman, Sakthivel Sadayappan, J. Seidman, 2019, Science Translational Medicine.

Abstract 571: MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy

J. Seidman, H. Watkins, C. Seidman, 2018, Circulation Research.

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

Christine E. Seidman, James A. Spudich, Robert S. McDowell, 2016, Science.

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm

W. Chung, J. Seidman, D. Srivastava, 2020, eLife.

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

Roger R Markwald, Christine E Seidman, J. Schmitt, 2010, The Journal of clinical investigation.

Glycogen storage diseases presenting as hypertrophic cardiomyopathy.

J. Seidman, J. Saul, B. Maron, 2005, The New England journal of medicine.

Droplet Digital PCR with EvaGreen Assay: Confirmational Analysis of Structural Variants

J. Gorham, Michael G Parfenov, Angela C. Tai, 2018, Current protocols in human genetics.

Robust identification of mosaic variants in congenital heart disease

K. B. Manheimer, W. Chung, J. Seidman, 2018, Human Genetics.

Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases

Adrian W. Briggs, G. Church, J. Seidman, 2012, PloS one.

Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency

Craig C. Benson, W. Chung, J. Seidman, 2021, Circulation research.

Novel and Annotated Long Noncoding RNAs Associated with Ischemia in the Human Heart

J. Seidman, V. Cameron, S. Aranki, 2021, International journal of molecular sciences.

Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

George Church, Wolfgang A. Linke, Stuart A. Cook, 2015, Science.

Loss of RNA expression and allele-specific expression associated with congenital heart disease

Yufeng Shen, Andrew J Sharp, Nihir Patel, 2016, Nature Communications.

Molecular profiling of dilated cardiomyopathy that progresses to heart failure.

Michael A. Burke, J. Seidman, C. Seidman, 2016, JCI insight.

Sex differences in gene expression in response to ischemia in the human myocardium

J. Seidman, B. Stranger, S. Aranki, 2018, bioRxiv.

Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation

Jourdan K. Ewoldt, S. Gygi, J. Seidman, 2021, Circulation research.

Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation

J. Seidman, J. Krieger, C. Seidman, 2023, Frontiers in Cellular and Infection Microbiology.

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

V. Mootha, J. Seidman, C. Seidman, 2017, Proceedings of the National Academy of Sciences.

Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease.

J. Seidman, J. Gorham, Danos C. Christodoulou, 2011, Current protocols in molecular biology.

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Michael A. Burke, J. Seidman, R. Gerszten, 2017, Cell reports.

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Michael A. Burke, J. Seidman, R. Gerszten, 2016, Cell reports.

Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia

J. Seidman, S. Aranki, S. Body, 2017, Cardiovascular Diabetology.

Robust identification of mosaic variants in congenital heart disease

K. B. Manheimer, J. Seidman, Yufeng Shen, 2018, Human Genetics.

Tbx5 maintains atrial identity by regulating an atrial enhancer network

J. Seidman, W. Pu, C. Seidman, 2023, bioRxiv.

Short Communication: The Cardiac Myosin Binding Protein C Arg502Trp Mutation: A Common Cause of Hypertrophic Cardiomyopathy

W. Chung, J. Seidman, H. Rehm, 2010, Circulation research.

Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice.

J. Seidman, C. Seidman, J. Gorham, 2015, Journal of molecular and cellular cardiology.

Sex differences in gene expression in response to ischemia in the human left ventricular myocardium.

J. Seidman, B. Stranger, S. Aranki, 2019, Human molecular genetics.

Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3

Craig C. Benson, P. Sorger, J. Seidman, 2018, Cell reports.

De novo mutations in Congenital Heart Disease with Neurodevelopmental and Other Birth Defects

Stephan J Sanders, M. Daly, W. Chung, 2016 .

as a genetic modifier in cardiomyopathy

M. Bulyk, A. Aboukhalil, C. Seidman, 2014 .

Genomic analyses implicate noncoding de novo variants in congenital heart disease

Gabor T. Marth, Kathleen M. Chen, K. B. Manheimer, 2020, Nature Genetics.

Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease

Parth N. Patel, J. Seidman, Yufeng Shen, 2023, Circulation. Genomic and precision medicine.

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease

K. B. Manheimer, W. Chung, J. Seidman, 2020, Genome Medicine.