H. Helminen

J. Arokoski, H. Helminen, S. Soimakallio, 1992, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Changes in subchondral bone mineral density and collagen matrix organization in growing horses.

P. R. van Weeren, M. Hyttinen, H. Helminen, 2008, Bone.

Studies on mammary gland involution. IV. Histochemical and biochemical observations on alterations in lysosomes and lysosomal enzymes.

S. Orrenius, H. Helminen, J. Ericsson, 1968, Journal of ultrastructure research.

Ultrastructural studies on prostatic involution in the rat. Mechanism of autophagy in epithelial cells, with special reference to the rough-surfaced endoplasmic reticulum.

H. Helminen, J. Ericsson, 1971, Journal of ultrastructure research.

Effect of radiosynovectomy with holmium-166 ferric hydroxide macroaggregate on adult equine cartilage.

M. Hyttinen, E. Vuorio, H. Helminen, 2004, The Journal of rheumatology.

Fixation, decalcification, and tissue processing effects on articular cartilage proteoglycans

H. Helminen, J. Jurvelin, A. Säämänen, 2004, Histochemistry.

Hsp90 inhibitor geldanamycin increases hsp70 mRNA stabilisation but fails to activate HSF1 in cells exposed to hydrostatic pressure.

H. Helminen, K. Kaarniranta, M. Lammi, 2005, Biochimica et biophysica acta.

Neuronal cells show regulatory differences in the hsp70 gene response.

T. Suuronen, A. Salminen, H. Helminen, 2002, Brain research. Molecular brain research.

Reticulon 4 in chondrocytic cells: barosensitivity and intracellular localization.

M. Hyttinen, K. Törrönen, H. Helminen, 2004, The international journal of biochemistry & cell biology.

High hydrostatic pressure induces ERK and PI3 kinase phosphorylation in human HCS-2/8 chondrosarcoma cells.

H. Helminen, R. Sironen, M. Lammi, 2004, Cellular and molecular biology.

Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation.

H. Helminen, J. Eriksson, L. Sistonen, 1998, Proceedings of the National Academy of Sciences of the United States of America.

CHAPTER VIII – THE CELLULAR MECHANISMS OF HORMONALLY INDUCED TISSUE ATROPHY

H. Helminen, 1975 .

Long-term voluntary exercise of male mice induces more beneficial effects on cancellous and cortical bone than on the collagenous matrix

H. Helminen, J. Jurvelin, P. Brama, 2009, Experimental Gerontology.

Articular cartilage thickness and glycosaminoglycan distribution in the young canine knee joint after remobilization of the immobilized limb

J. Arokoski, I. Kiviranta, H. Helminen, 1994, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone.

H. Helminen, R. Fässler, D. Prockop, 1995, Genes & development.

Effects of joint loading on articular cartilage collagen metabolism: assay of procollagen prolyl 4-hydroxylase and galactosylhydroxylysyl glucosyltransferase.

L. Peltonen, I. Kiviranta, H. Helminen, 1988, Connective tissue research.

Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility.

M. Hyttinen, H. Helminen, G. Kopen, 2001, The Biochemical journal.

More knee joint osteoarthritis (OA) in mice after inactivation of one allele of type II procollagen gene but less OA after lifelong voluntary wheel running exercise.

M. Hyttinen, H. Helminen, D. Prockop, 2001, Osteoarthritis and cartilage.

A histoquantitative study on the effects of castration on the rat ventral prostate lobe.

H. Helminen, E. Huttunen, T. Romppanen, 1981, Journal of anatomy.

Lifelong voluntary joint loading increases osteoarthritis in mice housing a deletion mutation in type II procollagen gene, and slightly also in non-transgenic mice

M. Hyttinen, E. Vuorio, H. Helminen, 2002, Annals of the rheumatic diseases.

The effects of various fixatives on the relative thickness of cellular membranes in the ventral lobe of the rat prostate

H. Helminen, A. Pelttari, 1979, The Histochemical Journal.

Improvements in the method for the electron microscopic localization of arylsulphatase activity

G. Glenner, H. Helminen, H. Kalimo, 1966, Histochemie.

Coordinated regulation of hyaluronan and aggrecan content in the articular cartilage of immobilized and exercised dogs.

J. Arokoski, I. Kiviranta, H. Helminen, 1996, The Journal of rheumatology.

Effects of enforced milk stasis on mammary gland epithelium, with special reference to changes in lysosomes and lysosomal enzymes.

H. Helminen, J. Ericsson, 1971, Experimental cell research.

Quantitation of lysosomal enzyme changes during enforced mammary gland involution.

H. Helminen, J. Ericsson, 1970, Experimental cell research.

Studies on mammary gland involution. I. On the ultrastructure of the lactating mammary gland.

H. Helminen, J. Ericsson, Jan L. E. Ericsson, 1968, Journal of ultrastructure research.

Studies on mammary gland involution. 3. Alterations outside auto- and heterophagocytic pathways for cytoplasmic degradation.

H. Helminen, J. Ericsson, 1968, Journal of ultrastructure research.

Proteoglycan alterations following immobilization and remobilization in the articular cartilage of young canine knee (stifle) joint

I. Kiviranta, H. Helminen, J. Jurvelin, 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Collagenase-Induced Changes in Articular Cartilage as Detected by Electron-Microscopic Stereology, Quantitative Polarized Light Microscopy and Biochemical Assays

H. Helminen, N. Oksala, V. Kovanen, 2002, Cells Tissues Organs.

Remobilization does not fully restore immobilization induced articular cartilage atrophy.

J. Arokoski, M. Hyttinen, I. Kiviranta, 1999, Clinical orthopaedics and related research.

Apoptosis of chondrocytes in transgenic mice lacking collagen II.

H. Helminen, D. Prockop, S. W. Li, 1997, Experimental cell research.

Short-term exercise-induced improvements in bone properties are for the most part not maintained during aging in hamsters

J. Arokoski, H. Helminen, J. Jurvelin, 2014, Experimental Gerontology.

Mutations in Type 1 Procollagen That Cause Osteogenesis Imperfecta: Effects of the Mutations on the Assembly of Collagen into Fibrils, the Basis of Phenotypic Variations, and Potential Antisense Therapies

H. Helminen, D. Prockop, A. Colige, 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The loss of enzyme reaction products from ultrathin sections during the staining for electron microscopy

H. Helminen, H. Kalimo, A. Arstila, 2004, Histochemie.

Lysosomal changes during castration-induced prostatic involution in the rat.

H. Helminen, J. Ericsson, M. Niemi, 1970, Acta pathologica et microbiologica Scandinavica. Section A, Pathology.

Studies on mammary gland involution. II. Ultrastructural evidence for auto- and heterophagocytosis.

H. Helminen, J. Ericsson, 1968, Journal of ultrastructure research.

Histochemical and biochemical studies on the localization and activity of lysosomal enzymes in fracture callus

H. Helminen, J. Ericsson, B. Arborgh, 1973, Histochemie.

Distribution of hyaluronan in articular cartilage as probed by a biotinylated binding region of aggrecan

J. Arokoski, H. Helminen, M. Tammi, 1996, Histochemistry and Cell Biology.

Cells and nuclei of articular cartilage chondrocytes in young rabbits enlarged after non-strenuous physical exercise.

I. Kiviranta, H. Helminen, J. Jurvelin, 1985, Journal of anatomy.

Morphometry of articular cartilage: A stereological method using light microscopy

H. Helminen, J. Jurvelin, K. Paukkonen, 1984, The Anatomical record.

A mouse model for Stickler's syndrome: ocular phenotype of mice carrying a targeted heterozygous inactivation of type II (pro)collagen gene (Col2a1).

H. Helminen, H. Uusitalo, K. Kaarniranta, 2006, Experimental eye research.

Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia.

L. Ala‐Kokko, H. Helminen, D. Prockop, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Site-specific immunostaining for type X collagen in noncalcified articular cartilage of canine stifle knee joint.

M. Hyttinen, I. Kiviranta, H. Helminen, 2002, Bone.

Spatial assessment of articular cartilage proteoglycans with Gd‐DTPA‐enhanced T1 imaging

Juha Töyräs, Jarno Rieppo, Johanna Silvennoinen, 2002, Magnetic resonance in medicine.

Levels of chondroitin-6-sulfate and nonaggregating proteoglycans at articular cartilage contact sites in the knees of young dogs subjected to moderate running exercise.

I. Kiviranta, H. Helminen, J. Jurvelin, 1989, Arthritis and rheumatism.

Biomechanical properties of the canine knee articular cartilage as related to matrix proteoglycans and collagen.

H J Helminen, M Tammi, J Jurvelin, 1988, Engineering in medicine.

Weight bearing controls glycosaminoglycan concentration and articular cartilage thickness in the knee joints of young beagle dogs.

H J Helminen, M Tammi, J Jurvelin, 1987, Arthritis and rheumatism.

Hydrostatic pressure-induced changes in cellular protein synthesis.

H. Helminen, K. Kaarniranta, R. Sironen, 2004, Biorheology.

An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice have osteoarthritic changes in joints.

L. Ala‐Kokko, H. Helminen, M. Tammi, 1993, The Journal of clinical investigation.

Proteoglycan alterations in rabbit knee articular cartilage following physical exercise and immobilization.

I. Kiviranta, H. Helminen, A. Säämänen, 1983, Connective tissue research.

Changes in spatial collagen content and collagen network architecture in porcine articular cartilage during growth and maturation.

H J Helminen, J Rieppo, J S Jurvelin, 2009, Osteoarthritis and cartilage.

The rate of calcium extraction during EDTA decalcification from thin bone slices as assessed with atomic absorption spectrophotometry

I. Kiviranta, H. Helminen, M. Tammi, 2004, Histochemistry.

Rough endoplasmic reticulum and fine intracytoplasmic filaments in articular cartilage chondrocytes of young rabbits; a stereological morphometric study using transmission electron microscopy.

H. Helminen, K. Paukkonen, 1987, Journal of anatomy.

Association between friction and wear in diarthrodial joints lacking lubricin

Khaled Elsaid, Heikki J Helminen, Gregory D Jay, 2007, Arthritis and rheumatism.

Decrease of proteoglycan granule number but increase of their size in articular cartilage of young rabbits after physical exercise and immobilization by splinting

H. Helminen, K. Paukkonen, Kari Paukkonen, 1987, The Anatomical record.

Application of selected cationic dyes for the semiquantitative estimation of glycosaminoglycans in histological sections of articular cartilage by microspectrophotometry

K. Törrönen, J. Arokoski, I. Kiviranta, 1996, The Histochemical Journal.

Effect of loading on the organization of the collagen fibril network in juvenile equine articular cartilage

P. R. van Weeren, M. Hyttinen, H. Helminen, 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Blood flow, histomorphology and elemental composition of the canine femur after physical training or immobilization.

I. Kiviranta, H. Helminen, J. Jurvelin, 1988, Acta physiologica Scandinavica.

Specimen preparation and quantification of collagen birefringence in unstained sections of articular cartilage using image analysis and polarizing light microscopy

J. Arokoski, M. Hyttinen, I. Kiviranta, 1997, The Histochemical Journal.

Effect of access to a running wheel on behavior of C57BL/6J mice.

H J Helminen, T Lapveteläinen, M. Hyttinen, 1999, Laboratory animal science.

Immobilisation causes longlasting matrix changes both in the immobilised and contralateral joint cartilage

I. Kiviranta, H. Helminen, M. Tammi, 1997, Annals of the rheumatic diseases.

Normal and pathological adaptations of articular cartilage to joint loading

H J Helminen, J S Jurvelin, J. Arokoski, 2000, Scandinavian journal of medicine & science in sports.

Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage.

Juha Töyräs, Rami K Korhonen, Jukka S Jurvelin, 2003, Journal of biomechanics.

Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation.

H J Helminen, R K Korhonen, M S Laasanen, 2002, Journal of biomechanics.

Biomechanical, biochemical and structural correlations in immature and mature rabbit articular cartilage.

M J Lammi, H J Helminen, J S Jurvelin, 2009, Osteoarthritis and cartilage.

Comparison of single-phase isotropic elastic and fibril-reinforced poroelastic models for indentation of rabbit articular cartilage.

Petro Julkunen, Jukka S Jurvelin, Heikki J Helminen, 2009, Journal of biomechanics.

Transgenic mouse models for studying the role of cartilage macromolecules in osteoarthritis.

M. Hyttinen, H. Helminen, H. Salminen, 2002, Rheumatology.

High hydrostatic pressure inhibits the biosynthesis of eukaryotic elongation factor‐2

H. Helminen, G. Browne, N. Redpath, 2005, Journal of cellular biochemistry.

Decline after immobilisation and recovery after remobilisation of synovial fluid IL1, TIMP, and chondroitin sulphate levels in young beagle dogs

V. Kosma, J. Arokoski, I. Kiviranta, 2001, Annals of the rheumatic diseases.

Regular joint loading in youth assists in the establishment and strengthening of the collagen network of articular cartilage and contributes to the prevention of osteoarthrosis later in life: a hypothesis

Mikko J. Lammi, Heikki J. Helminen, J. Arokoski, 2000, Journal of Bone and Mineral Metabolism.

Adaptation of canine femoral head articular cartilage to long distance running exercise in young beagles.

M. Hyttinen, H. Helminen, M. Tammi, 1993, Annals of the rheumatic diseases.

Effect of motion and load on articular cartilage in animal models

J. Arokoski, I. Kiviranta, H. Helminen, 1992 .

Joint loading-induced alterations in articular cartilage

Jukka S. Jurvelin, Heikki J. Helminen, I. Kiviranta, 1987 .

Separate lysosomal and secretory acid phosphatases in the rat ventral prostate.

H. Helminen, T. Vanha-Perttula, R. Niemi, 1972, Investigative urology.

Topographical variation of glycosaminoglycan content and cartilage thickness in canine knee (stifle) joint cartilage. Application of the microspectrophotometric method.

I. Kiviranta, H. Helminen, J. Jurvelin, 1987, Journal of anatomy.

Decreased birefringence of the superficial zone collagen network in the canine knee (stifle) articular cartilage after long distance running training, detected by quantitative polarised light microscopy.

T Lapveteläinen, J. Arokoski, M. Hyttinen, 1996, Annals of the rheumatic diseases.

Softening of the lateral condyle articular cartilage in the canine knee joint after long distance (up to 40 km/day) running training lasting one year.

J. Arokoski, I. Kiviranta, H. Helminen, 1994, International journal of sports medicine.

Proteoglycan and collagen alterations in canine knee articular cartilage following 20 km daily running exercise for 15 weeks.

I. Kiviranta, H. Helminen, J. Jurvelin, 1994, Connective tissue research.

Articular cartilage thickness and glycosaminoglycan distribution in the canine knee joint after strenuous running exercise.

H J Helminen, M Tammi, J Jurvelin, 1992, Clinical orthopaedics and related research.

Inactivation of one allele of the type II collagen gene alters the collagen network in murine articular cartilage and makes cartilage softer

M. Hyttinen, H. Helminen, J. Jurvelin, 2001, Annals of the rheumatic diseases.

The lack of effect of glucosamine sulphate on aggrecan mRNA expression and (35)S-sulphate incorporation in bovine primary chondrocytes.

H. Helminen, M. Lammi, C. Qu, 2006, Biochimica et biophysica acta.

Elevated levels of synovial fluid PLA2, stromelysin (MMP-3) and TIMP in early osteoarthrosis after tibial valgus osteotomy in young beagle dogs.

I. Kiviranta, H. Helminen, L. Lohmander, 1998, Acta orthopaedica Scandinavica.

Electromechanical film sensor device for dynamic force recordings from canine limbs

I. Kiviranta, T. Lyyra, H. Helminen, 1997 .

On the mechanism of lysosomal enzyme secretion. Electron microscopic and histochemical studies on the epithelial cells of the rat's ventral prostate lobe.

H. Helminen, J. Ericsson, 1970, Journal of ultrastructure research.

Ultrastructural studies on prostatic involution in the rat changes in the secretory pathways.

H. Helminen, J. Ericsson, 1972, Journal of ultrastructure research.

Transgenic mice expressing a partially deleted gene for type I procollagen (COL1A1). A breeding line with a phenotype of spontaneous fractures and decreased bone collagen and mineral.

H. Helminen, D. Prockop, E. Hume, 1993, The Journal of clinical investigation.

Differing patterns of acid phosphatase and cathepsin D activities in the rat ventral prostate gland during castration-induced prostatic involution.

H. Helminen, J. Ericsson, B. Arborgh, 1972, Acta endocrinologica.

Effect of long-term suppression and stimulation of rat thyroid with special reference to lysosomes.

H. Helminen, R. Seljelid, G. Thies, 1971, Experimental cell research.

Ultrastructural studies on prostatic involution in the rat. Evidence for focal irreversible damage to epithelium, and heterophagic digestion in macrophages.

H. Helminen, J. Ericsson, 1972, Journal of ultrastructure research.

Demonstration of chondroitin sulphate and glycoproteins in articular cartilage matrix using periodic acid-Schiff (PAS) method

I. Kiviranta, H. Helminen, J. Jurvelin, 2004, Histochemistry.

Functional adaptation of articular cartilage from birth to maturity under the influence of loading: a biomechanical analysis.

P. R. van Weeren, H. Helminen, J. Jurvelin, 2010, Equine veterinary journal.

Superficial zone of articular cartilage after immobilization and running training: is proteoglycan depletion the clue to the pathogenesis of osteoarthrosis

J. Arokoski, M. Hyttinen, I. Kiviranta, 1993 .

Fixation, decalcification, and tissue processing effects on articular cartilage proteoglycans

I. Kiviranta, H. Helminen, J. Jurvelin, 2004, Histochemistry.

Proteoglycan synthesis in canine intervertebral discs after long‐distance running training

I. Kiviranta, H. Helminen, M. Tammi, 1993, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Running training alters fiber type composition in spinal muscles

H. Helminen, M. Tammi, L. Paljärvi, 2006, European Spine Journal.

Practical considerations in the use of polarized light microscopy in the analysis of the collagen network in articular cartilage

Jukka S Jurvelin, Jarmo Hallikainen, Jarno Rieppo, 2008, Microscopy research and technique.

Gene expression profiles in chondrosarcoma cells subjected to cyclic stretching and hydrostatic pressure. A cDNA array study.

H. Helminen, M. Takigawa, K. Kaarniranta, 2003, Biorheology.

cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure.

K. Törrönen, H. Helminen, M. Takigawa, 2002, Biochimica et biophysica acta.

Increased bone mineral content and bone size in the femoral neck of men with hip osteoarthritis

J. Arokoski, H. Helminen, J. Jurvelin, 2002, Annals of the rheumatic diseases.

Lifelong moderate running training increases the incidence and severity of osteoarthritis in the knee joint of C57BL mice

J. Arokoski, M. Hyttinen, H. Helminen, 1995, The Anatomical record.

Prediction of biomechanical properties of articular cartilage with quantitative magnetic resonance imaging.

Juha Töyräs, Jukka S Jurvelin, Miika T Nieminen, 2004, Journal of biomechanics.

T2 relaxation reveals spatial collagen architecture in articular cartilage: A comparative quantitative MRI and polarized light microscopic study

J Silvennoinen, H J Helminen, J Töyräs, 2001, Magnetic resonance in medicine.

Quantitative MR microscopy of enzymatically degraded articular cartilage

J Silvennoinen, H J Helminen, J Töyräs, 2000, Magnetic Resonance in Medicine.

Comparison between Infrared and Raman Spectroscopic Analysis of Maturing Rabbit Cortical Bone

H. Helminen, J. Jurvelin, S. Saarakkala, 2011, Applied spectroscopy.

Hip muscle strength and muscle cross sectional area in men with and without hip osteoarthritis.

Markku Kankaanpää, Heikki J Helminen, J. Arokoski, 2002, The Journal of rheumatology.

Slowly progressive osteoarthritis after tibial valgus osteotomy in young beagle dogs.

I. Kiviranta, H. Helminen, H. Panula, 1997, Clinical orthopaedics and related research.

Topographical variation of the elastic properties of articular cartilage in the canine knee.

E B Hunziker, H J Helminen, J S Jurvelin, 2000, Journal of biomechanics.

Rabbit cortical bone tissue increases its elastic stiffness but becomes less viscoelastic with age.

H. Helminen, J. Jurvelin, H. Isaksson, 2010, Bone.

Physical function in men with and without hip osteoarthritis.

Heikki J Helminen, J. Arokoski, H. Helminen, 2004, Archives of physical medicine and rehabilitation.

Quantitative study of articular cartilage and subchondral bone remodeling in the knee joint of dogs after strenuous running training

J. Arokoski, H. Helminen, K. Abendroth, 1992, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro

H. Helminen, M. Tammi, M. Lammi, 1992, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage explants.

H. Helminen, M. Tammi, M. Lammi, 1993, Archives of biochemistry and biophysics.

Indentation stiffness of young canine knee articular cartilage--influence of strenuous joint loading.

H J Helminen, M Tammi, J Jurvelin, 1990, Journal of biomechanics.

Effects of aerobic long distance running training (up to 40 km · day−1) of 1-year duration on blood and endocrine parameters of female beagle dogs

J. Arokoski, H. Helminen, A. Säämänen, 2004, European Journal of Applied Physiology and Occupational Physiology.

Effects of growth and exercise on composition, structural maturation and appearance of osteoarthritis in articular cartilage of hamsters

Petro Julkunen, Jukka S Jurvelin, Jari Arokoski, 2010, Journal of anatomy.

Quantitative analysis of spatial proteoglycan content in articular cartilage with Fourier transform infrared imaging spectroscopy: Critical evaluation of analysis methods and specificity of the parameters

H J Helminen, J Rieppo, J S Jurvelin, 2009, Microscopy research and technique.

Training a large number of laboratory mice using running wheels and analyzing running behavior by use of a computer-assisted system.

P Halonen, A Tiihonen, H J Helminen, 1997, Laboratory animal science.

Do More Highly Organized Collagen Fibrils Increase Bone Mechanical Strength in Loss of Mineral Density After One‐Year Running Training?

M. Hyttinen, H. Helminen, V. Kovanen, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Maturation of collagen fibril network structure in tibial and femoral cartilage of rabbits.

H J Helminen, J S Jurvelin, P Julkunen, 2010, Osteoarthritis and cartilage.

Electron microscopic stereological study of collagen fibrils in bovine articular cartilage: volume and surface densities are best obtained indirectly (from length densities and diameters) using isotropic uniform random sampling

J. Arokoski, M. Hyttinen, H. Helminen, 1999, Journal of anatomy.

An improved light microscopical histoquantitative method for the stereological analysis of the rat ventral prostate lobe.

H. Helminen, E. Huttunen, T. Romppanen, 1980, Investigative urology.

Kuormituksen vaikutus nivelrustoon [The effects of loading on articular cartilage].

I. Kiviranta, H. Helminen, J. Jurvelin, 1992 .

[The effect of loading on articular cartilage].

I. Kiviranta, H. Helminen, J. Jurvelin, 1992, Duodecim; laaketieteellinen aikakauskirja.

H. Helminen, J. Jurvelin, S. Saarakkala, 2012, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Altered Golgi apparatus in hydrostatically loaded articular cartilage chondrocytes.

J J Parkkinen, M J Lammi, H J Helminen, 1993, Annals of the rheumatic diseases.

High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis.

K. Törrönen, H. Helminen, M. Takigawa, 2002, Biorheology.

Effects of glucosamine sulfate on intracellular UDP-hexosamine and UDP-glucuronic acid levels in bovine primary chondrocytes.

H. Helminen, S. Auriola, M. Lammi, 2007, Osteoarthritis and cartilage.

Articular cartilage superficial zone collagen birefringence reduced and cartilage thickness increased before surface fibrillation in experimental osteoarthritis

Alpo Pelttari, Heikki J Helminen, J. Arokoski, 1998, Annals of the rheumatic diseases.

Effect of endurance training on atrial natriuretic peptide gene expression in normal and hypertrophied hearts.

J. Arokoski, T. Takala, H. Helminen, 1994, Journal of applied physiology.

Joint Loading: Biology and Health of Articular Fractures

H. Helminen, 1988 .

Disturbed Synthesis of Type II Collagen Interferes with Rate of Bone Formation and Growth and Increases Bone Resorption in Transgenic Mice

H. Helminen, H. Malluche, M. Miettinen, 2008, Calcified Tissue International.

Sports, loading of cartilage, osteoarthritis and its prevention

H. Helminen, 2009, Scandinavian journal of medicine & science in sports.

Biomechanical and structural characteristics of canine femoral and tibial cartilage.

H J Helminen, J S Jurvelin, J. Arokoski, 1999, Journal of biomedical materials research.

Infrared spectroscopic analysis of human and bovine articular cartilage proteoglycans using carbohydrate peak or its second derivative

Simo Saarakkala, Jukka S Jurvelin, Lassi Rieppo, 2013, Journal of biomedical optics.

Cartilage Collagen Fibril Network in Newborn Transgenic Mice Analyzed by Electron Microscopic Stereology

H. Helminen, T. Långsjö, M. Arita, 2009, Cells Tissues Organs.

Orthopedics and Clinical Science

J. Arokoski, I. Kiviranta, T. Lyyra, 2022 .

In situ and ex vivo evaluation of an arthroscopic indentation instrument to estimate the health status of articular cartilage in the equine metacarpophalangeal joint.

P. R. van Weeren, H. Helminen, J. Jurvelin, 2006, Veterinary surgery : VS.

Chondrocyte ultrastructure in exercise and experimental osteoarthrosis. A stereologic morphometric study of articular cartilage of young rabbits using transmission electron microscopy.

H. Helminen, K. Paukkonen, 1987, Clinical orthopaedics and related research.

Quantitative morphological and biochemical investigations on the effects of physical exercise and immobilization on the articular cartilage of young rabbits.

I. Kiviranta, H. Helminen, J. Jurvelin, 1984, Acta biologica Hungarica.

Quantitation of autoradiographic grains in different zones of articular cartilage with image analyzer

H. Helminen, M. Tammi, M. Lammi, 2004, Histochemistry.

Effects of immobilization on the articular cartilage in young rabbits. A quantitative light microscopic stereological study.

H. Helminen, J. Jurvelin, K. Paukkonen, 1986, Clinical orthopaedics and related research.

A mechanical apparatus with microprocessor controlled stress profile for cyclic compression of cultured articular cartilage explants.

J J Parkkinen, M J Lammi, S Karjalainen, 1989, Journal of biomechanics.

Early bone growth on the surface of titanium implants in rat femur is enhanced by an amorphous diamond coating

H. Helminen, R. Korhonen, R. Lappalainen, 2011, Acta orthopaedica.

Long‐distance running alters bone anthropometry, elemental composition and mineral density of young dogs

H. Helminen, M. Tammi, L. Niemitukia, 1995, Scandinavian journal of medicine & science in sports.

Influence of age, site, and degenerative state on the speed of sound in equine articular cartilage.

P. R. van Weeren, A. Barneveld, H. Helminen, 2005, American journal of veterinary research.

A ten-track treadmill for running training of dogs.

J. Arokoski, I. Kiviranta, A. Tiihonen, 1991, Laboratory animal science.

Minor Influence of Lifelong Voluntary Exercise on Composition, Structure, and Incidence of Osteoarthritis in Tibial Articular Cartilage of Mice Compared with Major Effects Caused by Growth, Maturation, and Aging

J. Arokoski, M. Hyttinen, H. Helminen, 2011, Connective tissue research.

Age matters: collagen birefringence of superficial articular cartilage is increased in young guinea-pigs but decreased in older animals after identical physiological type of joint loading.

J J Parkkinen, M J Lammi, H J Helminen, 2001, Osteoarthritis and cartilage.

Functional consequences of cartilage degeneration in the equine metacarpophalangeal joint: quantitative assessment of cartilage stiffness.

H J Helminen, M S Laasanen, J S Jurvelin, 2010, Equine veterinary journal.

Transgenic Mice Expressing a Partially

H. Helminen, D. Prockop, E. Hume, 2013 .

Articular cartilage collagen birefringence is altered concurrent with changes in proteoglycan synthesis during dynamic in vitro loading

K Törrönen, J J Parkkinen, H J Helminen, 1998, The Anatomical record.

Effects of Long-term running on spinal mineral content in dogs

J. Arokoski, H. Helminen, S. Soimakallio, 2007, Calcified Tissue International.

Effects of mechanical loading and immobilization on the articular cartilage

J. Arokoski, M. Hyttinen, I. Kiviranta, 1997 .

A human COL2A1 gene with an Arg519Cys mutation causes osteochondrodysplasia in transgenic mice.

H. Helminen, D. Prockop, M. Lammi, 2004, Arthritis and rheumatism.

THE LOCALIZATION OF ARYL SULFATASE ACTIVITY IN THYROID FOLLICLE CELLS

H. Helminen, R. Seljelid, 1968, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Flat bed scanner in the quantitative assay of 35SO4-incorporation by X-ray film autoradiography of intervertebral disc sections

I. Kiviranta, H. Helminen, M. Tammi, 2004, Histochemistry.

Effects of immobilization for 6 weeks on rabbit knee articular surfaces as assessed by the semiquantitative stereomicroscopic method.

I. Kiviranta, H. Helminen, J. Jurvelin, 1983, Acta anatomica.

Influences of joint immobilization and running exercise on articular cartilage surfaces of young rabbits. A semiquantitative stereomicroscopic and scanning electron microscopic study.

I. Kiviranta, H. Helminen, J. Jurvelin, 1985, Acta anatomica.

INHIBITION OF RENAL ACID PHOSPHATASE AND ARYL SULFATASE ACTIVITY BY GLUTARALDEHYDE FIXATION

H. Helminen, J. Ericsson, B. Arborgh, 1971, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Effect of Running Exercise on Proteoglycans and Collagen Content in the Intervertebral Disc of Young Dogs

I. Kiviranta, H. Helminen, J. Jurvelin, 1993, International Journal of Sports Medicine.

Combination of digital image analysis and polarization microscopy: Theoretical considerations and experimental data

M. Hyttinen, H. Helminen, L. Módis, 1998, Microscopy research and technique.

The relative thickness of intracellular membranes in epithelial cells of the ventral lobe of the rat prostate

H. Helminen, A. Pelttari, 1979, The Histochemical Journal.

Effects of intra-articular injections of bufexamac suspension in healthy horses.

H. Helminen, R. Tulamo, Satu M. Sankari, 2001, American journal of veterinary research.