Yan Xu

Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.

Mark S. Sundrud, A. Regev, R. Young, 2014, Immunity.

Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders.

J. D. Elliott, Wei Zhang, Yan Xu, 2016, ACS medicinal chemistry letters.

Indole-propionic acid derivatives as potent, S1P3-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P1) receptor agonists.

J. D. Elliott, Wei Zhang, Yan Xu, 2012, Bioorganic & medicinal chemistry letters.

Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors.

J. D. Elliott, Yonghui Wang, Zhijun Xiang, 2015, ACS medicinal chemistry letters.

Discovery of novel N-(5-(arylcarbonyl)thiazol-2-yl)amides and N-(5-(arylcarbonyl)thiophen-2-yl)amides as potent RORγt inhibitors.

J. D. Elliott, Wei Zhang, Yonghui Wang, 2014, Bioorganic & medicinal chemistry.

Discovery of thiadiazole amides as potent, S1P₃-sparing agonists of sphingosine-1-phosphate 1 (S1P₁) receptor.

J. D. Elliott, Wei Zhang, Yonghui Wang, 2012, Bioorganic & medicinal chemistry letters.

Discovery of thiadiazole amides as potent, S1P₃-sparing agonists of sphingosine-1-phosphate 1 (S1P₁) receptor.

J. D. Elliott, Wei Zhang, Yonghui Wang, 2012, Bioorganic & medicinal chemistry letters.